VGAM
MCID: VNF001
MIFTS: 23

Vein of Galen Aneurysm (VGAM) malady

Categories: Rare diseases, Neuronal diseases, Cardiovascular diseases, Fetal diseases

Aliases & Classifications for Vein of Galen Aneurysm

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Sources:
31ICD10 via Orphanet, 40MESH via Orphanet, 48NIH Rare Diseases, 54Orphanet, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Vein of Galen Aneurysm:

Name: Vein of Galen Aneurysm 48 54 68
Vein of Galen Arteriovenous Malformations 54
Ectasia or Varix of the Vein of Galen 48
Vein of Galen Aneurysm Malformation 48
 
Galenic Arteriovenous Malformation 48
Galen Vein Aneurysm 48
Vgam 48

Characteristics:

Orphanet epidemiological data:

54
vein of galen aneurysm:
Inheritance: Not applicable; Age of onset: Antenatal,Infancy,Neonatal

Classifications:



External Ids:

Orphanet54 ORPHA1053
MESH via Orphanet40 C536535
ICD10 via Orphanet31 Q28.2
UMLS via Orphanet69 C0431420

Summaries for Vein of Galen Aneurysm

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NIH Rare Diseases:48 Vein of galen aneurysm is a rare form of arteriovenous malformation in which the embryonic precursor to the vein of galen, a vein at the base of the brain, dilates causing too much blood to rush to the heart. this can lead to rapid heart failure. other features may include increased head circumference resulting from hydrocephalus, unusually prominent veins on the face and scalp, developmental delay, persistent headache, and other neurological findings.  vein of galen aneurysm is often recognized on an ultrasound late in pregnancy. in other cases, it is diagnosed after birth. although the exact cause remains unknown, this condition appears to result from a defect in early fetal development. treatment is aimed at decreasing the blood flow through the malformation while maximizing the blood supply to the brain. minimally invasive surgical techniques are preferred, such as endovascular embolization. last updated: 9/11/2016

MalaCards based summary: Vein of Galen Aneurysm, also known as vein of galen arteriovenous malformations, is related to aneurysm and thrombosis, and has symptoms including Array, Array and Array. Affiliated tissues include heart, brain and pineal.

Related Diseases for Vein of Galen Aneurysm

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Diseases related to Vein of Galen Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1aneurysm10.7
2thrombosis10.1
3congestive heart failure10.0
4hydrocephalus10.0
5parkes weber syndrome9.8
6galactosemia9.8
7pulmonary hypertension9.8
8spastic diplegia9.8
9arteriovenous malformation9.8
10aseptic meningitis9.8
11meningitis9.8
12hemoglobinemia9.8
13weber syndrome9.8
14spasticity9.8

Graphical network of diseases related to Vein of Galen Aneurysm:



Diseases related to vein of galen aneurysm

Symptoms & Phenotypes for Vein of Galen Aneurysm

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Human phenotypes related to Vein of Galen Aneurysm:

 54 64
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 aneurysm64 54 Frequent (79-30%) HP:0002617
2 abnormality of the cerebral vasculature64 54 Very frequent (99-80%) HP:0100659
3 peripheral arteriovenous fistula64 54 Frequent (79-30%) HP:0100784

Drugs & Therapeutics for Vein of Galen Aneurysm

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Vein of Galen Aneurysm

Genetic Tests for Vein of Galen Aneurysm

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Anatomical Context for Vein of Galen Aneurysm

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MalaCards organs/tissues related to Vein of Galen Aneurysm:

36
Heart, Brain, Pineal

Publications for Vein of Galen Aneurysm

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Articles related to Vein of Galen Aneurysm:

(show top 50)    (show all 52)
idTitleAuthorsYear
1
EP02.09: Early and uncommon prenatal diagnosis of vein of Galen aneurysm. (27645455)
2016
2
Pure word deafness after resection of a Vein of Galen aneurysm and arteriovenous malformation: report of a case. (24956543)
2014
3
Teaching neuroimages: vein of Galen aneurysm mimicking pineal mass in a young adult. (23713094)
2013
4
Endovascular management of vein of galen aneurysm malformation: A series of two case reports. (21977085)
2011
5
MR and Diffusion Tensor Imaging of Vein of Galen Aneurysmal Malformation in an Infant Presenting with Spastic Diplegia and Seizures. A Case Report. (24148343)
2010
6
Confirmation of T1-bright vein of Galen aneurysm spontaneous thrombosis by subtraction magnetic resonance venography: a case report. (19626473)
2009
7
Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused by RASA1 mutations. (18446851)
2008
8
Prenatal magnetic resonance imaging of vein of Galen aneurysm associated with congestive heart failure. (19067899)
2008
9
Vein of Galen aneurysmal malformation and galactosemia in a neonate: a previously unreported association. (17986048)
2007
10
Vein of Galen aneurysm in an adult: case report. (17057899)
2006
11
Vein of Galen aneurysm complicated with pulmonary hypertension: report of one newborn case. (17016967)
2006
12
Vein of Galen aneurysm: antenatal diagnosis: a case report. (16304858)
2005
13
Vein of Galen aneurysm malformation (VGAM): closing the management loop. (15055912)
2004
14
Spectrum of clinical presentations of vein of galen aneurysm. (15163883)
2004
15
Vein of Galen aneurysm: anatomical study of an adult autopsy case. (15300864)
2004
16
Hemodynamic analysis of an adult vein of Galen aneurysm malformation by use of 3D image-based computational fluid dynamics. (12812929)
2003
17
Prenatal diagnosis of a vein of galen aneurysm. (12566774)
2003
18
Surgical treatment of the thrombosed vein of galen aneurysm. (12376772)
2002
19
Disseminated coagulopathy associated with transtorcular embolization of vein of Galen aneurysm in a neonate. (10685204)
1999
20
Special imaging casebook. Vein of Galen aneurysm. (8817440)
1996
21
Prenatal diagnosis and prognosis of a vein of Galen aneurysm assessed by pulsed and color Doppler sonography. (8705421)
1996
22
Prenatal sonographic diagnosis of a vein of Galen aneurysm: relevance of associated malformations for timing and mode of delivery. (8590193)
1995
23
A vein of Galen aneurysm with an abnormal drain system: MRI findings. (7491195)
1995
24
Prenatal magnetic resonance imaging detection of a vein of Galen aneurysm. (8306350)
1993
25
The increase in plethysmographic amplitude due to the clipping of the vein of Galen aneurysm. (8346849)
1993
26
Pathologic findings in a patient with a vein of Galen aneurysm treated by staged endovascular embolization. (8481943)
1993
27
Color Doppler sonography as a primary diagnostic tool in the diagnosis of vein of Galen aneurysm in a critically ill neonate. (7904055)
1993
28
Vein of Galen aneurysm: MRI with a fast gradient refocusing pulse sequence. (8332410)
1993
29
Early diagnosis of a vein of Galen aneurysm: report of a case. (1363216)
1992
30
Vein of Galen aneurysm presenting in middle age. (1449674)
1992
31
Vein of Galen aneurysm and hydrocephalus. (1794114)
1991
32
Case report: in utero diagnosis of a vein of Galen aneurysm using colour flow Doppler. (1959310)
1991
33
Vein of Galen aneurysm presenting with recurrent aseptic meningitis and subsequent spontaneous thrombosis. (2330533)
1990
34
Vein of Galen aneurysm. (2228099)
1990
35
Vein of Galen aneurysm associated with dural AVM and straight sinus thrombosis. Case report. (3339446)
1988
36
Successful surgical and anesthetic management of vein of Galen aneurysm in a neonate in congestive heart failure. (3380281)
1988
37
Anesthetic management of hemodynamic changes during vein of Galen aneurysm clipping. (3195776)
1988
38
Hemoglobinemia and renal failure from an intracerebral hematoma simulating a vein of Galen aneurysm. (3614590)
1987
39
Spontaneous thrombosis of a vein of Galen aneurysm. (3120540)
1987
40
In utero diagnosis of a vein of Galen aneurysm by ultrasound. (6399929)
1984
41
Vascular steal associated with vein of Galen aneurysm. (6544380)
1984
42
Vein of Galen aneurysm. (6619087)
1983
43
Diagnosis of a vein of Galen aneurysm by ultrasound. (6811625)
1982
44
Thrombosed vein of Galen aneurysm. (7070623)
1982
45
Unusual manifestation of vein of Galen aneurysm. (6810676)
1982
46
Vein of Galen aneurysm - diagnosis by real-time ultrasound. (7328101)
1981
47
Turner's syndrome and vein of Galen aneurysm--a previously unreported association. (7349577)
1981
48
Hydrocephalus associated with arterio-venous malformation - the vein of Galen aneurysm. (551620)
1979
49
Vein of Galen aneurysm: successful excision of a completely thrombosed aneurysm in an infant. (4810450)
1974
50
Vein of Galen aneurysm. (4722476)
1973

Variations for Vein of Galen Aneurysm

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Expression for genes affiliated with Vein of Galen Aneurysm

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Search GEO for disease gene expression data for Vein of Galen Aneurysm.

Pathways for genes affiliated with Vein of Galen Aneurysm

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GO Terms for genes affiliated with Vein of Galen Aneurysm

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Sources for Vein of Galen Aneurysm

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet