Vein of Galen Aneurysm malady

NIH Rare Diseases: Vein of Galen aneurysm is a rare form of arteriovenous malformation in which a particular vein at the base of the brain, the vein of Galen, dilates causing too much blood to rush to the heart and leading to congestive heart failure. Sometimes the defect will be recognized on an ultrasound before birth, but most often it is seen in infants who experience rapid heart failure. In less severe cases, a child may develop hydrocephalus because the enlarged malformation blocks the normal flow or absorption of cerebrospinal fluid. Although the exact cause remains unknown, this condition appears to be a result of a defect in early fetal development.³⁰

MalaCards: Vein of Galen Aneurysm, also known as ectasia or varix of the vein of galen, is related to weber syndrome and parkes weber syndrome. An important gene associated with Vein of Galen Aneurysm is RASA1 (RAS p21 protein activator (GTPase activating protein) 1). Affiliated tissues include brain, heart and fetal brain.

vein of galen aneurysm 30 ectasia or varix of the vein of galen 30 vein of galen aneurysm malformation 30

galenic arteriovenous malformation 30 galen vein aneurysm 30 vgam 30

Diseases related to vein of galen aneurysm by text searches and GeneDecks gene sharing:

id	Related Disease	Score	Top Affiliating Genes
1	weber syndrome	8.1
2	parkes weber syndrome	8.1

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to vein of galen aneurysm:

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Articles related to vein of galen aneurysm:

id	Title	Authors	Year	Affiliating Genes
1	Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused by RASA1 mutations. (18446851)	Revencu N.... Vikkula M.	2008	RASA1

Genes related to vein of galen aneurysm according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	RASA1	RAS p21 protein activator (GTPase activating protein) 1	11.0	Publications, Disorders