MCID: VNF001
MIFTS: 25

Vein of Galen Aneurysm malady

Categories: Rare diseases, Neuronal diseases, Cardiovascular diseases, Fetal diseases

Aliases & Classifications for Vein of Galen Aneurysm

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Sources:
46NIH Rare Diseases, 52Orphanet, 66UMLS, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Vein of Galen Aneurysm:

Name: Vein of Galen Aneurysm 46 52 66
Vein of Galen Arteriovenous Malformations 52
Ectasia or Varix of the Vein of Galen 46
Vein of Galen Aneurysm Malformation 46
 
Galenic Arteriovenous Malformation 46
Galen Vein Aneurysm 46
Vgam 46

Characteristics:

Orphanet epidemiological data:

52
vein of galen aneurysm:
Inheritance: Not applicable; Age of onset: Antenatal,Infancy,Neonatal

Classifications:



External Ids:

Orphanet52 ORPHA1053
ICD10 via Orphanet29 Q28.2
MESH via Orphanet38 C536535
UMLS via Orphanet67 C0431420

Summaries for Vein of Galen Aneurysm

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NIH Rare Diseases:46 Vein of galen aneurysm is a rare form of arteriovenous malformation in which the embryonic precursor to the vein of galen, a vein at the base of the brain, dilates causing too much blood to rush to the heart. this can lead to rapid heart failure. other features may include increased head circumference resulting from hydrocephalus, unusually prominent veins on the face and scalp, developmental delay, persistent headache, and other neurological findings.  vein of galen aneurysm is often recognized on an ultrasound late in pregnancy. in other cases, it is diagnosed after birth. although the exact cause remains unknown, this condition appears to result from a defect in early fetal development. treatment is aimed at decreasing the blood flow through the malformation while maximizing the blood supply to the brain. minimally invasive surgical techniques are preferred, such as endovascular embolization. last updated: 9/11/2016

MalaCards based summary: Vein of Galen Aneurysm, also known as vein of galen arteriovenous malformations, is related to aneurysm and congestive heart failure, and has symptoms including abnormality of the cerebral vasculature, aneurysm and peripheral arteriovenous fistula. Affiliated tissues include heart, brain and pineal.

Related Diseases for Vein of Galen Aneurysm

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Diseases related to Vein of Galen Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
idRelated DiseaseScoreTop Affiliating Genes
1aneurysm10.8
2congestive heart failure10.1
3hydrocephalus10.1
4parkes weber syndrome10.0
5galactosemia10.0
6pulmonary hypertension10.0
7spastic diplegia10.0
8arteriovenous malformation10.0
9aseptic meningitis10.0
10meningitis10.0
11hemoglobinemia10.0
12weber syndrome10.0
13spasticity10.0

Graphical network of diseases related to Vein of Galen Aneurysm:



Diseases related to vein of galen aneurysm

Symptoms for Vein of Galen Aneurysm

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Symptoms:

 52
  • aneurysm
  • abnormality of the cerebral vasculature
  • peripheral arteriovenous fistula

HPO human phenotypes related to Vein of Galen Aneurysm:

id Description Frequency HPO Source Accession
1 abnormality of the cerebral vasculature hallmark (90%) HP:0100659
2 aneurysm typical (50%) HP:0002617
3 peripheral arteriovenous fistula typical (50%) HP:0100784

Drugs & Therapeutics for Vein of Galen Aneurysm

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Vein of Galen Aneurysm

Genetic Tests for Vein of Galen Aneurysm

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Anatomical Context for Vein of Galen Aneurysm

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MalaCards organs/tissues related to Vein of Galen Aneurysm:

34
Heart, Brain, Pineal

Animal Models for Vein of Galen Aneurysm or affiliated genes

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Publications for Vein of Galen Aneurysm

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Articles related to Vein of Galen Aneurysm:

(show top 50)    (show all 52)
idTitleAuthorsYear
1
EP02.09: Early and uncommon prenatal diagnosis of vein of Galen aneurysm. (27645455)
2016
2
Pure word deafness after resection of a Vein of Galen aneurysm and arteriovenous malformation: report of a case. (24956543)
2014
3
Teaching neuroimages: vein of Galen aneurysm mimicking pineal mass in a young adult. (23713094)
2013
4
Endovascular management of vein of galen aneurysm malformation: A series of two case reports. (21977085)
2011
5
MR and Diffusion Tensor Imaging of Vein of Galen Aneurysmal Malformation in an Infant Presenting with Spastic Diplegia and Seizures. A Case Report. (24148343)
2010
6
Confirmation of T1-bright vein of Galen aneurysm spontaneous thrombosis by subtraction magnetic resonance venography: a case report. (19626473)
2009
7
Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fast-flow vascular anomalies are caused by RASA1 mutations. (18446851)
2008
8
Prenatal magnetic resonance imaging of vein of Galen aneurysm associated with congestive heart failure. (19067899)
2008
9
Vein of Galen aneurysmal malformation and galactosemia in a neonate: a previously unreported association. (17986048)
2007
10
Vein of Galen aneurysm complicated with pulmonary hypertension: report of one newborn case. (17016967)
2006
11
Vein of Galen aneurysm in an adult: case report. (17057899)
2006
12
Vein of Galen aneurysm: anatomical study of an adult autopsy case. (15300864)
2004
13
Spectrum of clinical presentations of vein of galen aneurysm. (15163883)
2004
14
Vein of Galen aneurysm malformation (VGAM): closing the management loop. (15055912)
2004
15
Hemodynamic analysis of an adult vein of Galen aneurysm malformation by use of 3D image-based computational fluid dynamics. (12812929)
2003
16
Prenatal diagnosis of a vein of galen aneurysm. (12566774)
2003
17
Surgical treatment of the thrombosed vein of galen aneurysm. (12376772)
2002
18
Disseminated coagulopathy associated with transtorcular embolization of vein of Galen aneurysm in a neonate. (10685204)
1999
19
Prenatal diagnosis and prognosis of a vein of Galen aneurysm assessed by pulsed and color Doppler sonography. (8705421)
1996
20
Special imaging casebook. Vein of Galen aneurysm. (8817440)
1996
21
A vein of Galen aneurysm with an abnormal drain system: MRI findings. (7491195)
1995
22
Prenatal sonographic diagnosis of a vein of Galen aneurysm: relevance of associated malformations for timing and mode of delivery. (8590193)
1995
23
Pathologic findings in a patient with a vein of Galen aneurysm treated by staged endovascular embolization. (8481943)
1993
24
The increase in plethysmographic amplitude due to the clipping of the vein of Galen aneurysm. (8346849)
1993
25
Prenatal magnetic resonance imaging detection of a vein of Galen aneurysm. (8306350)
1993
26
Color Doppler sonography as a primary diagnostic tool in the diagnosis of vein of Galen aneurysm in a critically ill neonate. (7904055)
1993
27
Vein of Galen aneurysm: MRI with a fast gradient refocusing pulse sequence. (8332410)
1993
28
Vein of Galen aneurysm presenting in middle age. (1449674)
1992
29
Early diagnosis of a vein of Galen aneurysm: report of a case. (1363216)
1992
30
Case report: in utero diagnosis of a vein of Galen aneurysm using colour flow Doppler. (1959310)
1991
31
Vein of Galen aneurysm and hydrocephalus. (1794114)
1991
32
Vein of Galen aneurysm presenting with recurrent aseptic meningitis and subsequent spontaneous thrombosis. (2330533)
1990
33
Vein of Galen aneurysm. (2228099)
1990
34
Vein of Galen aneurysm associated with dural AVM and straight sinus thrombosis. Case report. (3339446)
1988
35
Successful surgical and anesthetic management of vein of Galen aneurysm in a neonate in congestive heart failure. (3380281)
1988
36
Anesthetic management of hemodynamic changes during vein of Galen aneurysm clipping. (3195776)
1988
37
Spontaneous thrombosis of a vein of Galen aneurysm. (3120540)
1987
38
In utero diagnosis of a vein of Galen aneurysm by ultrasound. (6399929)
1984
39
Vascular steal associated with vein of Galen aneurysm. (6544380)
1984
40
Vein of Galen aneurysm. (6619087)
1983
41
Unusual manifestation of vein of Galen aneurysm. (6810676)
1982
42
Thrombosed vein of Galen aneurysm. (7070623)
1982
43
Diagnosis of a vein of Galen aneurysm by ultrasound. (6811625)
1982
44
Turner's syndrome and vein of Galen aneurysm--a previously unreported association. (7349577)
1981
45
Vein of Galen aneurysm - diagnosis by real-time ultrasound. (7328101)
1981
46
Hydrocephalus associated with arterio-venous malformation - the vein of Galen aneurysm. (551620)
1979
47
Vein of Galen aneurysm: successful excision of a completely thrombosed aneurysm in an infant. (4810450)
1974
48
Vein of Galen aneurysm. (4722476)
1973
49
Pneumoencephalographic findings in a case of vein of Galen aneurysm. (5117054)
1971
50
Excision of thrombosed vein of Galen aneurysm in an infant. Case report. (5304310)
1968

Variations for Vein of Galen Aneurysm

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Expression for genes affiliated with Vein of Galen Aneurysm

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Search GEO for disease gene expression data for Vein of Galen Aneurysm.

Pathways for genes affiliated with Vein of Galen Aneurysm

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GO Terms for genes affiliated with Vein of Galen Aneurysm

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Sources for Vein of Galen Aneurysm

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet