MCID: VNZ002
MIFTS: 42

Venezuelan Equine Encephalitis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Venezuelan Equine Encephalitis

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Aliases & Descriptions for Venezuelan Equine Encephalitis:

Name: Venezuelan Equine Encephalitis 10 45 12
Encephalomyelitis, Venezuelan Equine 36
Venezuelan Equine Encephalomyelitis 65
 
Encephalitis Venezuelan Equine 47
Venezuelan Equine Fever 10

Classifications:



External Ids:

Disease Ontology10 DOID:9584
ICD1027 A92.2
ICD9CM29 066.2
MeSH36 D004685
NCIt42 C35121
UMLS65 C0014078

Summaries for Venezuelan Equine Encephalitis

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Disease Ontology:10 A viral infectious disease that results in inflammation located in brain of horses and humans, has material basis in Venezuelan equine encephalitis virus, which is transmitted by Culex mosquitoes. The infection has symptom fever, has symptom chills, has symptom malaise, has symptom severe headache, has symptom photophobia, and has symptom myalgia in the legs and lumbosacral region.

MalaCards based summary: Venezuelan Equine Encephalitis, also known as encephalomyelitis, venezuelan equine, is related to encephalitis and lymphoma, and has symptoms including fever, chills and malaise. An important gene associated with Venezuelan Equine Encephalitis is RPSA (Ribosomal Protein SA), and among its related pathways are IL6-mediated signaling events and Interferon Pathway. Affiliated tissues include brain of horses, brain and breast, and related mouse phenotype hematopoietic system.

Related Diseases for Venezuelan Equine Encephalitis

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Graphical network of the top 20 diseases related to Venezuelan Equine Encephalitis:



Diseases related to venezuelan equine encephalitis

Symptoms for Venezuelan Equine Encephalitis

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Symptoms:

 10
  • fever
  • chills
  • malaise
  • severe headache
  • photophobia
  • myalgia in the legs

Drugs & Therapeutics for Venezuelan Equine Encephalitis

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Drugs for Venezuelan Equine Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1VaccinesPhase 2, Phase 16085
2Immunologic FactorsPhase 118483
3MitogensPhase 11386

Interventional clinical trials:

idNameStatusNCT IDPhase
1Safety and Immunogenicity Study of the Venezuelan Equine Encephalomyelitis VaccineEnrolling by invitationNCT00582504Phase 2
2Safety and Immunogenicity of Venezuelan Equine Encephalomyelitis Vaccine (VEE C-84) as a Booster to VEE TC-83SuspendedNCT00582088Phase 2
3Study of a DNA-based Venezuelan Equine Encephalitis Virus DNA Vaccine Administered by Electroporation in Healthy VolunteersCompletedNCT01984983Phase 1
4A Phase I Study To Evaluate The Antitumor Activity And Safety Of AVX901Active, not recruitingNCT01526473Phase 1
5Safety, Tolerability and Immunogenicity of the Venezuelan Equine Encephalitis (VEE) Attenuated Live-Virus VaccineWithdrawnNCT00109304Phase 1

Search NIH Clinical Center for Venezuelan Equine Encephalitis


Cochrane evidence based reviews: encephalomyelitis, venezuelan equine

Genetic Tests for Venezuelan Equine Encephalitis

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Anatomical Context for Venezuelan Equine Encephalitis

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MalaCards organs/tissues related to Venezuelan Equine Encephalitis:

33
Brain, Breast, Bone, T cells, Lung, Endothelial, Spinal cord

FMA organs/tissues related to Venezuelan Equine Encephalitis:

16
Brain of horses

Animal Models for Venezuelan Equine Encephalitis or affiliated genes

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MGI Mouse Phenotypes related to Venezuelan Equine Encephalitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.6ERF, LGALS3, RPSA, STAT1, STAT2

Publications for Venezuelan Equine Encephalitis

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Articles related to Venezuelan Equine Encephalitis:

(show top 50)    (show all 409)
idTitleAuthorsYear
1
Combined Analysis of Plasma Amphiregulin and Heregulin Predicts Response to Cetuximab in Metastatic Colorectal Cancer. (26569500)
2015
2
Comparative analysis of MCP-1 and TF in elderly patients with acute exacerbations of COPD and its clinical significance. (25683933)
2015
3
Cat-scratch disease: a wide spectrum of clinical pictures. (26161064)
2015
4
Positive clinical outcome with IVIg as monotherapy in recurrent pemphigoid gestationis. (25765353)
2015
5
Investigating the antiviral role of cell death-inducing DFF45-like effector B in HCV replication. (24980280)
2014
6
Structure and function of the ascending aorta in palliated transposition of the great arteries. (21930312)
2013
7
Transfusion-related acute lung injury: A dangerous and underdiagnosed noncardiogenic pulmonary edema. (23913451)
2013
8
Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels. (22100703)
2012
9
Autobiographical accounts of sensing in Asperger syndrome and high-functioning autism. (22999038)
2012
10
Esophagitis dissecans superficialis. (21549372)
2011
11
Acute paediatric compartment syndrome of the hand caused by hereditary angiooedema. (22004624)
2011
12
Comparative utility of cytokine levels and quantitative RD-1-specific T cell responses for rapid immunodiagnosis of tuberculous meningitis. (21880971)
2011
13
Chronic periapical periodontitis containing mature human hair shaft: a case report. (21667835)
2011
14
Serum apolipoproteins C-I and C-III are reduced in stomach cancer patients: results from MALDI-based peptidome and immuno-based clinical assays. (21267442)
2011
15
Carnitine palmitoyltransferase 2: New insights on the substrate specificity and implications for acylcarnitine profiling. (20538056)
2010
16
Decreases in human dendritic cell-dependent T(H)2-like responses after acute in vivo IgE neutralization. (20132969)
2010
17
Inhibition of evi1 expression by siRNA in HEL cell line]. (21176350)
2010
18
A study of monoamine neuronal systems of schizophrenic patients: using forensic autopsy brains. (19282221)
2009
19
Interaction between a chromosome 10 RET enhancer and chromosome 21 in the Down syndrome-Hirschsprung disease association. (19306335)
2009
20
Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. (17292824)
2007
21
Parkin enhances mitochondrial biogenesis in proliferating cells. (16449237)
2006
22
Differential toxicity of antimonial compounds and their effects on glutathione homeostasis in a human leukaemia monocyte cell line. (16318845)
2006
23
Steroid-responsive subacute polymyositis in an adult following respiratory syncytial virus infection. (16409434)
2006
24
Avascular necrosis of the femoral head as the first manifestation of acute lymphoblastic leukemia. (16502568)
2006
25
Regulation of collagen type I in vascular smooth muscle cells by competition between Nkx2.5 and deltaEF1/ZEB1. (15226419)
2004
26
Sydenham's chorea--an entity in progress. (15326832)
2004
27
Phosphatidylserine receptor cooperates with high-density lipoprotein receptor in recognition of apoptotic cells by thymic nurse cells. (15072554)
2004
28
MA1ller cells express the neuronal progenitor cell marker nestin in both differentiated and undifferentiated human foetal retina. (12786777)
2003
29
Clinical and genetic heterogeneity in benign hereditary chorea. (12196653)
2002
30
Endocrine activities of alexamorelin (Ala-His-d-2-methyl-Trp-Ala-Trp-d-Phe-Lys-NH2), a synthetic GH secretagogue, in humans. (11022186)
2000
31
Apolipoprotein E gene polymorphism and risk of hypercholesterolemia: a case control study in a working population of Valencia]. (10996872)
2000
32
Low-dose expression of a human apolipoprotein E transgene in macrophages restores cholesterol efflux capacity of apolipoprotein E-deficient mouse plasma. (9636193)
1998
33
Inhibition of Fcgamma receptor-mediated phagocytosis by a nonphagocytic Fcgamma receptor. (9473244)
1998
34
Role of opioid tone in the pathophysiology of hyperinsulinemia and insulin resistance in polycystic ovarian disease. (9472963)
1998
35
Production of hepatocyte growth factor is increased in chronic renal failure. (9031263)
1997
36
Molecular and cellular mechanisms of antidepressant drugs. (9166647)
1996-1997
37
The efficacy of 9-cis retinoic acid in experimental models of cancer. (8825126)
1996
38
Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage. (8682794)
1996
39
Sequence analysis of the human hTg737 gene and its polymorphic sites in patients with autosomal recessive polycystic kidney disease. (8597639)
1995
40
One-megabase yeast artificial chromosome and 400-kilobase cosmid-phage contigs containing the von Hippel-Lindau tumor suppressor and Ca(2+)-transporting adenosine triphosphatase isoform 2 genes. (8162598)
1994
41
Qualitative and quantitative studies of cytokines synthesized and secreted by non-human primate peripheral blood mononuclear cells. (8142603)
1993
42
Interleukin-2: a possible trigger for autoimmunity. (1597345)
1992
43
Inhibition of Ca(2+)-induced calcitonin secretion by somatostatin: roles of voltage dependent Ca2+ channels and G-proteins. (1349229)
1992
44
A blocking monoclonal antibody to endothelial-leukocyte adhesion molecule-1 (ELAM1). (1697461)
1990
45
Hemorrhagic fever with renal syndrome. (2647265)
1989
46
Nailfold capillary microscopy in essential mixed cryoglobulinemia: a report of several cases. (4037423)
1985
47
Recent upper respiratory tract infection and pityriasis rosea: a case-control study of 249 matched pairs. (6849825)
1983
48
A case of focal dermal hypoplasia. (7083620)
1982
49
C1 inhibitor deficiency simulating systemic lupus erythematosus. (7073969)
1982
50
Management of chronic or intermittent primary angle-closure glaucoma: a long-term follow-up of the results of peripheral iridectomy used as an initial procedure. (760772)
1979

Variations for Venezuelan Equine Encephalitis

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Expression for genes affiliated with Venezuelan Equine Encephalitis

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Search GEO for disease gene expression data for Venezuelan Equine Encephalitis.

Pathways for genes affiliated with Venezuelan Equine Encephalitis

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GO Terms for genes affiliated with Venezuelan Equine Encephalitis

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Biological processes related to Venezuelan Equine Encephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of type I interferon-mediated signaling pathwayGO:00603389.8STAT1, STAT2
2defense response to virusGO:00516079.4STAT1, STAT2

Sources for Venezuelan Equine Encephalitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet