MCID: VNZ002
MIFTS: 60

Venezuelan Equine Encephalitis malady

Rare diseases, Infectious diseases categories

Summaries for Venezuelan Equine Encephalitis

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9Disease Ontology, 66Wikipedia, 34MalaCards
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Disease Ontology:9 A viral infectious disease that results in inflammation located in brain of horses and humans, has material basis in venezuelan equine encephalitis virus, which is transmitted by culex mosquitoes. the infection has symptom fever, has symptom chills, has symptom malaise, has symptom severe headache, has symptom photophobia, and has symptom myalgia in the legs and lumbosacral region.

MalaCards: Venezuelan Equine Encephalitis, also known as venezuelan equine encephalomyelitis, is related to encephalitis and eastern equine encephalitis, and has symptoms including myalgia in the legs, photophobia and severe headache. An important gene associated with Venezuelan Equine Encephalitis is IL32 (interleukin 32), and among its related pathways are Immune response IL 12 signaling pathway and Cytokines and Inflammatory Response. The compounds mumps and p113 have been mentioned in the context of this disorder. Affiliated tissues include brain of horses, brain and t cells, and related mouse phenotypes are liver/biliary system and tumorigenesis.

Wikipedia:66 Venezuelan equine encephalitis virus is a mosquito-borne viral pathogen that causes Venezuelan equine... more...

Aliases & Classifications for Venezuelan Equine Encephalitis

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9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 28ICD9CM, 36MeSH, 41NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


Aliases & Descriptions:

venezuelan equine encephalitis 9 44 11
venezuelan equine encephalomyelitis 63
encephalitis venezuelan equine 46


External Ids:

Disease Ontology9 DOID:9584
ICD9CM28 066.2
MeSH36 D004685
NCIt41 C35121

Related Diseases for Venezuelan Equine Encephalitis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Venezuelan Equine Encephalitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1encephalitis32.5IFNA1, CCL2
2eastern equine encephalitis30.9SH2D3C
3chikungunya30.8SH2D3A, SH2D3C
4mumps30.6STAT2, STAT1
5hepatitis30.5IFNB1, STAT1, IFNA1
6herpes simplex30.4IFNA1, IFNB1, STAT1
7encephalomyelitis30.4IFNG, IFNB1, CCL2
8influenza30.3STAT1, IFNG, IFNB1, IFNA1, FURIN
9vaccinia10.7
10tick-borne encephalitis10.5
11neuronitis10.5
12st. louis encephalitis10.5
13cowpox10.3
14rift valley fever10.3
15western equine encephalitis10.3
16japanese encephalitis10.3
17lyme disease10.3
18yellow fever10.3
19ebola hemorrhagic fever10.3
20cerebritis10.3
21mouth disease10.3
22stomatitis10.3
23hemorrhagic fever10.3
24hiv-110.3
25chronic inflammatory demyelinating polyradiculoneuropathy10.1IFNB1
26autosomal dominant hyper ige syndrome10.1TYK2
27severe acute respiratory syndrome10.1SH2D3A, SH2D3C
28periapical granuloma10.1CCL2
29gastroenteritis10.1SH2D3A, SH2D3C
30thyroiditis10.1IFNA1
31newcastle disease10.1IFNB1, IFNA1
32hypothyroidism10.1IFNA1, IFNB1
33congenital stationary night blindness, type 1f10.0IFNA1, IFNB1
34fibrosarcoma10.0TYK2, STAT2, IFNB1, STAT1
35tropical spastic paraparesis10.0IFNB1, IFNG
36candidiasis10.0IFNG
37viral hepatitis10.0IFNB1, IFNA1, STAT1
38hairy cell leukemia10.0IFNB1, IFNA1
39severe combined immunodeficiency10.0IFNG, IFNB1, TYK2
40pleural tuberculosis10.0CCL2, IFNG
41sezary's disease10.0IFNA1, IFNG
42squamous cell carcinoma of the head and neck10.0CCL2, LGALS3, FURIN
43relapsing-remitting multiple sclerosis10.0IFNB1, IFNG, IFNA1
44factor vii deficiency10.0IFNB1, IFNG, IFNA1
45malignant glioma10.0FURIN, IL32, STAT1, IFNB1, LGALS3
46monocytic leukemia10.0CCL2, IFNB1, IFNG
47cutaneous t cell lymphoma10.0STAT1, IFNG, IFNA1
48colon cancer10.0STAT1, LGALS3, IL32, RPSA, SAT1, STAT2
49lung cancer10.0RPSA, FURIN, SAT1, IFNB1, STAT1
50atopic dermatitis10.0IFNG, LGALS3, CCL2

Graphical network of the top 20 diseases related to Venezuelan Equine Encephalitis:



Diseases related to venezuelan equine encephalitis

Symptoms for Venezuelan Equine Encephalitis

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Sources:
9Disease Ontology
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Symptoms:

9
  • myalgia in the legs
  • photophobia
  • severe headache
  • malaise
  • chills
  • fever

Drugs & Therapeutics for Venezuelan Equine Encephalitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Venezuelan Equine Encephalitis

Drug clinical trials:

Search ClinicalTrials for Venezuelan Equine Encephalitis

Search NIH Clinical Center for Venezuelan Equine Encephalitis

Search CenterWatch for Venezuelan Equine Encephalitis

Genetic Tests for Venezuelan Equine Encephalitis

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Anatomical Context for Venezuelan Equine Encephalitis

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34MalaCards, 15FMA
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MalaCards organs/tissues related to Venezuelan Equine Encephalitis:

34
Brain, T cells, Olfactory bulb, Myeloid, Testes, Pancreas, Kidney, Spleen

FMA organs/tissues related to Venezuelan Equine Encephalitis:

15
Brain of horses

Animal Models for Venezuelan Equine Encephalitis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Venezuelan Equine Encephalitis:

38 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.8IFNG, CCL2, STAT1, SAT1, FURIN
2MP:00020068.8IFNG, IFNB1, CCL2, STAT1, SAT1
3MP:00053908.5ERF, LGALS3, STAT1, TYK2, IFNG, CCL2
4MP:00028738.3IFNG, IFNB1, CCL2, SAT1, STAT1, FURIN
5MP:00053858.3CCL2, ERF, RPSA, IFNG, LGALS3, STAT1
6MP:00053788.0STAT1, TYK2, FURIN, SAT1, CCL2, IFNG
7MP:00053847.9TYK2, SAT1, STAT1, LGALS3, CCL2, SH2D3C
8MP:00053767.8IFNG, SAT1, STAT1, LGALS3, CCL2, IFNB1
9MP:00053877.6CCL2, IFNG, IFNB1, LGALS3, STAT1, STAT2
10MP:00107687.3ERF, RPSA, IFNG, CCL2, LGALS3, STAT1
11MP:00053977.1RPSA, TYK2, FURIN, SH2D3C, STAT2, LGALS3
12MP:00036317.0ERF, IFNB1, FURIN, STAT1, LGALS3, CCL2

Publications for Venezuelan Equine Encephalitis

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Sources:
53PubMed
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Articles related to Venezuelan Equine Encephalitis:

(show top 50)    (show all 386)
idTitleAuthorsYear
1
Artificial microRNAs can effectively inhibit replication of Venezuelan equine encephalitis virus. (23988697)
2013
2
Specific detection of all members of the Venezuelan Equine Encephalitis complex: development of a RT-Nested PCR. (22609888)
2012
3
Venezuelan equine encephalitis in a teenager visiting Central America. (22472656)
2012
4
Infected dendritic cells are sufficient to mediate the adjuvant activity generated by Venezuelan equine encephalitis virus replicon particles. (22531556)
2012
5
First detection of Rio Negro virus (Venezuelan equine encephalitis complex subtype VI) in CA^rdoba, Argentina. (22310545)
2012
6
Analysis of intrahost variation in Venezuelan equine encephalitis virus reveals repeated deletions in the 6-kilodalton protein gene. (21715498)
2011
7
4.4 A8 cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus. (21829169)
2011
8
T cells facilitate recovery from Venezuelan equine encephalitis virus-induced encephalomyelitis in the absence of antibody. (20181704)
2010
9
Interplay of acute and persistent infections caused by Venezuelan equine encephalitis virus encoding mutated capsid protein. (20668087)
2010
10
Alpha interferon as an adenovirus-vectored vaccine adjuvant and antiviral in Venezuelan equine encephalitis virus infection. (19264673)
2009
11
Isolation and phylogenetic analysis of Mucambo virus (Venezuelan equine encephalitis complex subtype IIIA) in Trinidad. (19631956)
2009
12
IRES-dependent replication of Venezuelan equine encephalitis virus makes it highly attenuated and incapable of replicating in mosquito cells. (18501401)
2008
13
Vector competence of eastern and western forms of Psorophora columbiae (Diptera: Culicidae) mosquitoes for enzootic and epizootic Venezuelan equine encephalitis virus. (18337337)
2008
14
A human dendritic cell subset receptive to the Venezuelan equine encephalitis virus-derived replicon particle constitutively expresses IL-32. (18768856)
2008
15
Adaptation of Venezuelan equine encephalitis virus lacking 51-nt conserved sequence element to replication in mammalian and mosquito cells. (17292936)
2007
16
Venezuelan equine encephalitis virus vaccine candidate (V3526) safety, immunogenicity and efficacy in horses. (17240002)
2007
17
Purification, crystallization and X-ray diffraction analysis of the C-terminal protease domain of Venezuelan equine encephalitis virus nsP2. (16754969)
2006
18
Determining functionally important amino acid residues of the E1 protein of Venezuelan equine encephalitis virus. (16607494)
2006
19
Venezuelan equine encephalitis virus entry mechanism requires late endosome formation and resists cell membrane cholesterol depletion. (16427678)
2006
20
Postepizootic persistence of Venezuelan equine encephalitis virus, Venezuela. (16485478)
2005
21
Ecological characterization of the aquatic habitats of mosquitoes (Diptera: Culicidae) in enzootic foci of Venezuelan equine encephalitis virus in western Venezuela. (15962775)
2005
22
Development of immunofiltration assay by light addressable potentiometric sensor with genetically biotinylated recombinant antibody for rapid identification of Venezuelan equine encephalitis virus. (15251409)
2004
23
Susceptibility of Ochlerotatus taeniorhynchus (Diptera: Culicidae) to infection with epizootic (subtype IC) and enzootic (subtype ID) Venezuelan equine encephalitis viruses: evidence for epizootic strain adaptation. (15535633)
2004
24
Functional enhancement of a partially active single-chain variable fragment antibody to Venezuelan equine encephalitis virus. (12828872)
2003
25
Immune protection against staphylococcal enterotoxin-induced toxic shock by vaccination with a Venezuelan equine encephalitis virus replicon. (11930333)
2002
26
Short report: Isolation and identification of Venezuelan equine encephalitis virus from a human in Panama. (12363053)
2002
27
Role of interferon and interferon regulatory factors in early protection against Venezuelan equine encephalitis virus infection. (10208925)
1999
28
Limited potential for mosquito transmission of genetically engineered, live-attenuated Venezuelan equine encephalitis virus vaccine candidates. (10403340)
1999
29
Gene gun mediated vaccination is superior to manual delivery for immunisation with DNA vaccines expressing protective antigens from Yersinia pestis or Venezuelan Equine Encephalitis virus. (10547416)
1999
30
Effect of salt concentration in larval rearing water on susceptibility of Aedes Mosquitoes (Diptera: Culicidae) to eastern equine and Venezuelan equine encephalitis viruses. (9775590)
1998
31
Nucleotide sequences of the 26S mRNAs of the viruses defining the Venezuelan equine encephalitis antigenic complex. (9886206)
1998
32
Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector. (9060663)
1997
33
Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. (9434729)
1997
34
Apoptotic cell death is an important cause of neuronal injury in experimental Venezuelan equine encephalitis virus infection of mice. (9113200)
1997
35
Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America. (7777497)
1995
36
Murine T-helper cell immune response to recombinant vaccinia-Venezuelan equine encephalitis virus. (8085379)
1994
37
Molecular evidence that epizootic Venezuelan equine encephalitis (VEE) I-AB viruses are not evolutionary derivatives of enzootic VEE subtype I-E or II viruses. (8445371)
1993
38
Venezuelan equine encephalitis virus propagation in the olfactory tract of normal and immunized mice. (1841630)
1991
39
Protection against lethal Venezuelan equine encephalitis (VEE) virus infection by cell-free supernatant obtained from immune spleen cells. (1698216)
1990
40
Genetic variation of Venezuelan equine encephalitis virus strains of the ID variety in Colombia. (3341520)
1988
41
Recombinant vaccinia virus/Venezuelan equine encephalitis (VEE) virus protects mice from peripheral VEE virus challenge. (3184276)
1988
42
Central nervous system alterations as sequelae of Venezuelan equine encephalitis virus infection in the rat. (469656)
1979
43
Production of Venezuelan equine encephalitis virus in cells grown on artificial capillaries. (637540)
1978
44
Human Venezuelan equine encephalitis virus infection in Florida. (4823800)
1974
45
Experimental infection and intracage transmission of Venezuelan equine encephalitis virus (subtype IB) among cotton rats, Sigmodon hispidus (Say and Ord). (4429187)
1974
46
Venezuelan equine encephalitis virus infection in man. (4824504)
1974
47
Surveillance of Venezuelan equine encephalitis in the United States--1972. (4149690)
1973
48
Alterations in immune responses by attenuated Venezuelan equine encephalitis vaccine. II. Pathology and soluble antigen localization in guinea pigs. (4890323)
1969
49
Ecology of Venezuelan equine encephalitis virus in Panama. (4904962)
1969
50
Epidemiological aspects of venezuelan equine encephalitis virus infections. (16350203)
1967

Variations for Venezuelan Equine Encephalitis

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Expression for genes affiliated with Venezuelan Equine Encephalitis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Venezuelan Equine Encephalitis

Search GEO for disease gene expression data for Venezuelan Equine Encephalitis.

Pathways for genes affiliated with Venezuelan Equine Encephalitis

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Sources:
51PathCards, 61Thomson Reuters, 39NCBI BioSystems Database, 54QIAGEN, 56Reactome, 31KEGG, 55R&D Systems, 5Cell Signaling Technology
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Pathways related to Venezuelan Equine Encephalitis according to GeneCards/GeneDecks:

(show all 34)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8TYK2, IFNG
29.8IFNB1, IFNG
3
Show member pathways
9.7RAB5A, RAB7A
49.7STAT2, STAT1, TYK2
5
Show member pathways
9.7STAT2, STAT1, TYK2
69.5TYK2, STAT1, CCL2
7
Show member pathways
MAPK Cascade39
Immune response Oncostatin M signaling via MAPK in human cells61
Oncostatin M Signaling Pathway39
9.5CCL2, STAT1, TYK2
8
Show member pathways
IFN-gamma pathway39
9.5IFNG, STAT1, STAT2
9
Show member pathways
9.5STAT1, TYK2, IFNG
10
Show member pathways
9.5TYK2, IFNG, STAT1
11
Show member pathways
Transcription NF kB signaling pathway61
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response61
9.5STAT1, IFNB1, IFNG
129.4LGALS3, CCL2, IFNG
13
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways61
Immune response IL 1 signaling pathway61
9.4STAT1, IFNA1, IFNB1
149.3IFNG, RAB5A, RAB7A
15
Show member pathways
Immune response CD16 signaling in NK cells61
9.3IFNA1, IFNB1, IFNG
169.3IFNA1, IFNB1, IFNG
17
Show member pathways
IL27-mediated signaling events39
9.3IFNG, TYK2, STAT1, STAT2
18
Show member pathways
Development Thrombopoetin signaling via JAK STAT pathway61
9.3STAT2, STAT1, IFNG, TYK2
19
Show member pathways
Immune response IL 12 induced IFN gamma production61
9.3TYK2, IFNG, STAT1, RAB7A
209.3STAT1, STAT2, IFNB1, IFNG
219.2IFNA1, RAB5A, IFNB1
22
Show member pathways
IL23-mediated signaling events39
Immune response IL 10 signaling pathway61
Angiopoietin receptor Tie2-mediated signaling39
Development PDGF signaling via STATs and NF kB61
Development Angiopoietin Tie2 signaling61
9.1IFNG, CCL2, TYK2, STAT1
239.0STAT2, IFNB1, TYK2, IFNG, STAT1
24
Show member pathways
8.9STAT2, STAT1, IFNB1, IFNA1, TYK2
258.9STAT1, TYK2, IFNB1, STAT2, IFNA1
268.8STAT2, SH2D3C, RAB5A, STAT1
27
Show member pathways
8.6TYK2, CCL2, IFNA1, IFNB1, IFNG
288.5IFNG, STAT2, IFNB1, IFNA1, STAT1, TYK2
29
Show member pathways
Type III interferon signaling39
8.5IFNA1, TYK2, IFNB1, STAT2, STAT1, IFNG
30
Show member pathways
8.5STAT2, STAT1, IFNA1, IFNB1, IFNG, TYK2
31
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
8.4IFNA1, IFNB1, CCL2, STAT1, STAT2, IFNG
328.2RAB7A, RAB5A, IFNB1, IFNA1, IFNG, STAT1
33
Show member pathways
8.1IFNB1, IFNG, IFNA1, CCL2, STAT2, TYK2
34
Show member pathways
7.8CCL2, IFNA1, IFNB1, STAT1, STAT2, FURIN

Compounds for genes affiliated with Venezuelan Equine Encephalitis

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Sources:
46Novoseek, 12DrugBank, 62Tocris Bioscience, 30IUPHAR, 52PharmGKB, 3BitterDB, 25HMDB
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Compounds related to Venezuelan Equine Encephalitis according to GeneCards/GeneDecks:

(show top 50)    (show all 83)
idCompoundScoreTop Affiliating Genes
1mumps4610.3STAT2, STAT1
2p1134610.1STAT2, IFNA1
3cycloferon469.9IFNA1, IFNG
4rebif469.9IFNB1, IFNA1
5avonex469.8IFNA1, IFNB1
6betaseron469.7IFNB1, IFNG, IFNA1
7mezerein469.7IFNG, IFNB1, IFNA1
8kynurenine469.7IFNA1, IFNB1, IFNG
9glatiramer acetate46 1210.7IFNG, IFNB1, IFNA1
10tetracycline46 1210.6IFNB1, FURIN, CCL2, SAT1
11inosine monophosphate469.6IFNA1, STAT1, IFNB1
12acyclovir46 1210.6IFNG, IFNA1, IFNB1
13il-12469.5CCL2, IFNA1, IFNG
14il 10469.5CCL2, IFNG, IFNB1
15tarc469.4CCL2, IFNB1, IFNG
16herbimycin a46 6210.4CCL2, IFNG, STAT1, IFNB1
17indoleamine469.4IFNG, STAT1, IFNA1, IFNB1
18imiquimod46 62 30 1212.4STAT1, IFNA1, IFNB1, IFNG
19polyinosinic-polycytidylic acid469.4IFNG, STAT1, IFNA1, IFNB1
20poly(i-c)469.4IFNG, STAT1, IFNA1, IFNB1
21ribavirin46 52 1211.4IFNG, IFNB1, IFNA1, STAT1
22matrigel469.4STAT1, LGALS3, RPSA, IL32
23endotoxin469.4IFNB1, CCL2, STAT1, IFNG
24ccl346 3010.3CCL2, IFNG, IFNB1, IFNA1
25sb 20358046 6210.2SAT1, IFNG, IFNB1, CCL2, STAT1
26genistein46 30 62 3 25 1214.2STAT1, IFNG, STAT2, CCL2, IFNB1
272,5-oligoadenylate469.2STAT2, STAT1, IFNB1, IFNG, IFNA1
28etoposide46 52 62 1212.2STAT1, RPSA, LGALS3, IFNB1, IFNA1
295-aza-2deoxycytidine469.2IFNG, IFNA1, STAT1, IFNB1
30pge2469.1CCL2, IFNG, IFNB1, STAT1, SAT1
315fluorouracil469.1SAT1, IFNA1, CCL2, IFNG, IFNB1
32wortmannin469.1STAT1, RAB5A, TYK2, CCL2, LGALS3
33superoxide46 2510.0IFNB1, CCL2, LGALS3, FURIN, STAT1
34rantes469.0IFNB1, IFNA1, CCL2, IFNG, STAT1
35ifn-alpha468.9IFNA1, STAT1, STAT2, TYK2, IFNB1, IFNG
36cisplatin46 52 62 1211.9LGALS3, CCL2, IFNB1, IFNA1, STAT1, SAT1
37retinoid468.9IFNG, IFNB1, IFNA1, STAT1
38arginine468.8SAT1, FURIN, STAT1, CCL2, IFNG, LGALS3
39alanine468.8IFNB1, IFNA1, LGALS3, TYK2, FURIN, SAT1
40actinomycin d468.8IFNA1, IFNB1, IFNG, SAT1, STAT1, CCL2
41phosphatidylinositol468.8STAT1, TYK2, RAB5A, RAB7A, CCL2, LGALS3
42cycloheximide468.7SAT1, STAT1, CCL2, IFNB1, IFNA1, IFNG
43retinoic acid46 259.6IFNG, STAT1, TYK2, IFNA1, LGALS3, IFNB1
44vegf468.5STAT1, IL32, IFNG, IFNB1, IFNA1, LGALS3
45cysteine468.4IFNB1, IFNG, RPSA, LGALS3, FURIN, RAB5A
46estrogen468.3IFNB1, FURIN, STAT1, LGALS3, RPSA, BCAR3
47lipid468.2CCL2, LGALS3, STAT1, RAB7A, FURIN, RPSA
48glucose468.1RAB5A, IFNB1, CCL2, STAT1, SAT1, FURIN
49serine468.1LGALS3, TYK2, CCL2, IFNB1, FURIN, STAT2
50tyrosine468.0STAT1, TYK2, FURIN, STAT2, LGALS3, IFNA1

GO Terms for genes affiliated with Venezuelan Equine Encephalitis

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Sources:
17Gene Ontology
See all sources

Cellular components related to Venezuelan Equine Encephalitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.5IL32, FURIN, LGALS3, CCL2, IFNB1, IFNG
2cytosolGO:0058298.4SAT1, TYK2, STAT2, RPSA, RAB5A, ERF
3extracellular vesicular exosomeGO:0700628.2FURIN, LGALS3, RPSA, RAB7A, RAB5A, TYK2

Biological processes related to Venezuelan Equine Encephalitis according to GeneCards/GeneDecks:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of metanephric nephron tubule epithelial cell differentiationGO:07230810.0STAT1, IFNG
2negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:00334010.0IFNG, STAT1
3macrophage chemotaxisGO:04824610.0CCL2, LGALS3
4positive regulation of membrane protein ectodomain proteolysisGO:0510449.9IFNG, FURIN
5monocyte chemotaxisGO:0025489.9CCL2, LGALS3
6regulation of interferon-gamma-mediated signaling pathwayGO:0603349.9STAT1, IFNG
7JAK-STAT cascadeGO:0072599.9CCL2, STAT1, STAT2
8positive regulation of peptidyl-serine phosphorylation of STAT proteinGO:0331419.8IFNG, IFNB1
9regulation of type I interferon-mediated signaling pathwayGO:0603389.7TYK2, STAT2, STAT1, IFNB1
10type I interferon signaling pathwayGO:0603379.7IFNB1, STAT1, STAT2, TYK2
11neutrophil chemotaxisGO:0305939.7LGALS3, CCL2, IFNG
12humoral immune responseGO:0069599.6IFNG, IFNB1, CCL2
13defense response to virusGO:0516079.5IFNG, IFNB1, STAT1, STAT2
14lipopolysaccharide-mediated signaling pathwayGO:0316639.5CCL2, STAT1
15cell surface receptor signaling pathwayGO:0071669.3CCL2, IFNB1, IFNG
16viral processGO:0160329.3RPSA, STAT1, STAT2, FURIN
17cytokine-mediated signaling pathwayGO:0192219.0IFNG, IFNB1, CCL2, STAT1, STAT2, TYK2
18response to drugGO:0424938.8STAT1, CCL2, IFNG, BCAR3
19small GTPase mediated signal transductionGO:0072648.1SH2D3A, SH2D3C, BCAR3, RAB7A, RAB5A

Molecular functions related to Venezuelan Equine Encephalitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1laminin bindingGO:0432369.9RPSA, LGALS3
2cytokine activityGO:0051259.3IFNB1, IFNG, IL32
3guanyl-nucleotide exchange factor activityGO:0050858.6BCAR3, SH2D3C, SH2D3A
4protein bindingGO:0055157.0TYK2, SAT1, STAT2, STAT1, LGALS3, IL32

Products for genes affiliated with Venezuelan Equine Encephalitis

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Sources for Venezuelan Equine Encephalitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet