MCID: VNS011
MIFTS: 18

Venous Thrombosis, Protection Against malady

Blood diseases category
Download this MalaCard

Summaries for Venous Thrombosis, Protection Against

About this section


Fully expand this MalaCard
MalaCards based summary: Venous Thrombosis, Protection Against is related to deep venous thrombosis, protection against and venous thrombosis. An important gene associated with Venous Thrombosis, Protection Against is F13A1 (coagulation factor XIII, A1 polypeptide), and among its related pathways are Hemostasis and Collagen biosynthesis and modifying enzymes. The compounds heparinoids and kininogen have been mentioned in the context of this disorder. Related mouse phenotype respiratory system.

Description from OMIM:46 188050

Aliases & Classifications for Venous Thrombosis, Protection Against

About this section

Venous Thrombosis, Protection Against, Aliases & Descriptions:

Name: Venous Thrombosis, Protection Against 46


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood diseases


Related Diseases for Venous Thrombosis, Protection Against

About this section

Diseases related to Venous Thrombosis, Protection Against via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1deep venous thrombosis, protection against10.4
2venous thrombosis10.2F2
3factor xii deficiency10.2F13A1
4dysfibrinogenemia9.9F13A1, F2
5pulmonary embolism9.9F13A1, F2
6thrombophilia9.9F2, F13A1
7liver cancer9.9F13A1, F2
8factor v leiden thrombophilia9.8F13A1, F2

Graphical network of diseases related to Venous Thrombosis, Protection Against:



Diseases related to venous thrombosis, protection against

Symptoms for Venous Thrombosis, Protection Against

About this section


Clinical features from OMIM:

188050

Drugs & Therapeutics for Venous Thrombosis, Protection Against

About this section

Drug clinical trials:

Search ClinicalTrials for Venous Thrombosis, Protection Against

Search NIH Clinical Center for Venous Thrombosis, Protection Against

Genetic Tests for Venous Thrombosis, Protection Against

About this section

Anatomical Context for Venous Thrombosis, Protection Against

About this section

Animal Models for Venous Thrombosis, Protection Against or affiliated genes

About this section

MGI Mouse Phenotypes related to Venous Thrombosis, Protection Against:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.1F13A1, F2

Publications for Venous Thrombosis, Protection Against

About this section

Variations for Venous Thrombosis, Protection Against

About this section

Clinvar genetic disease variations for Venous Thrombosis, Protection Against:

6
id Gene Name Type Significance SNP ID Assembly Location
1F2NM_000506.3(F2): c.*97G> Asingle nucleotide variantPathogenic, risk factorrs1799963GRCh37Chr 11, 46761055: 46761055
2F2NM_000506.3(F2): c.1787G> T (p.Arg596Leu)single nucleotide variantPathogenicrs387907201GRCh37Chr 11, 46760876: 46760876

Expression for genes affiliated with Venous Thrombosis, Protection Against

About this section
Expression patterns in normal tissues for genes affiliated with Venous Thrombosis, Protection Against

Search GEO for disease gene expression data for Venous Thrombosis, Protection Against.

Pathways for genes affiliated with Venous Thrombosis, Protection Against

About this section

Pathways related to Venous Thrombosis, Protection Against according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1F13A1, F2
2
Show member pathways
9.1F13A1, F2
3
Show member pathways
Complement Activation, Classical Pathway37
Complement and Coagulation Cascades37
9.1F13A1, F2
4
Show member pathways
9.1F13A1, F2

Compounds for genes affiliated with Venous Thrombosis, Protection Against

About this section
Sources:
44Novoseek, 50PharmGKB, 28IUPHAR, 24HMDB, 11DrugBank
See all sources

Compounds related to Venous Thrombosis, Protection Against according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1heparinoids449.3F13A1, F2
2kininogen449.2F13A1, F2
3aspirin44 50 28 2412.2F13A1, F2
4fibrinogen449.1F2, F13A1
5estrogen449.1F13A1, F2
6heparin44 28 24 1112.0F13A1, F2
7adp44 28 2410.8F13A1, F2

GO Terms for genes affiliated with Venous Thrombosis, Protection Against

About this section

Cellular components related to Venous Thrombosis, Protection Against according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1F13A1, F2
2blood microparticleGO:0725628.8F13A1, F2

Biological processes related to Venous Thrombosis, Protection Against according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood coagulationGO:0075969.1F13A1, F2
2platelet activationGO:0301688.8F13A1, F2

Products for genes affiliated with Venous Thrombosis, Protection Against

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Venous Thrombosis, Protection Against

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet