MCID: VNT009
MIFTS: 16

Ventricular Tachycardia, Idiopathic malady

Categories: Genetic diseases, Rare diseases

Aliases & Classifications for Ventricular Tachycardia, Idiopathic

About this section

Aliases & Descriptions for Ventricular Tachycardia, Idiopathic:

Name: Ventricular Tachycardia, Idiopathic 52 12
 
Familial Ventricular Tachycardia 48 27 68

Characteristics:

HPO:

64
ventricular tachycardia, idiopathic:
Inheritance: autosomal dominant inheritance

Classifications:



External Ids:

OMIM52 192605

Summaries for Ventricular Tachycardia, Idiopathic

About this section
MalaCards based summary: Ventricular Tachycardia, Idiopathic, also known as familial ventricular tachycardia, is related to catecholaminergic polymorphic ventricular tachycardia, and has symptoms including sudden cardiac death, abnormality of metabolism/homeostasis and paroxysmal ventricular tachycardia. An important gene associated with Ventricular Tachycardia, Idiopathic is GNAI2 (G Protein Subunit Alpha I2).

Description from OMIM:52 192605

Related Diseases for Ventricular Tachycardia, Idiopathic

About this section

Diseases related to Ventricular Tachycardia, Idiopathic via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1catecholaminergic polymorphic ventricular tachycardia11.0

Symptoms & Phenotypes for Ventricular Tachycardia, Idiopathic

About this section

Symptoms by clinical synopsis from OMIM:

192605

Clinical features from OMIM:

192605

Human phenotypes related to Ventricular Tachycardia, Idiopathic:

 64
id Description HPO Frequency HPO Source Accession
1 sudden cardiac death64 HP:0001645
2 abnormality of metabolism/homeostasis64 HP:0001939
3 paroxysmal ventricular tachycardia64 HP:0004751

Drugs & Therapeutics for Ventricular Tachycardia, Idiopathic

About this section

Drugs for Ventricular Tachycardia, Idiopathic (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
SpironolactoneapprovedPhase 32321952-01-7, 52-01-75833
Synonyms:
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
AB00513806
AC-4214
AC1L1L8Q
Abbolactone
Acelat
Aldace
Aldactazide
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Alphapharm Brand of Spironolactone
Alpharma Brand of Spironolactone
Alter Brand of Spironolactone
Altex
Aquareduct
Ashbourne Brand of Spironolactone
Azupharma Brand of Spironolactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
CHEBI:428201
CHEBI:45692
CHEBI:9241
CHEMBL1393
CID5833
CPD000471892
Cardel Brand of Spironolactone
D00443
D013148
DB00421
Deverol
Dexo Brand of Spironolactone
Diatensec
Dira
Duraspiron
EINECS 200-133-6
Espironolactona
Espironolactona Alter
Espironolactona Mundogen
Espironolactona [INN-Spanish]
Euteberol
Flumach
Frumikal
Generosan Brand of Spironolactone
HMS1568I18
HMS2090N21
HSDB 3184
Hormosan Brand of Spironolactone
I06-1970
Jenapharm Brand of Spironolactone
Jenaspiron
LS-118614
LT00772287
Lacalmin
Lacdene
Laractone
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
Mayoly-Spindler Brand of Spironolactone
Melarcon
Merck dura Brand of Spironolactone
Mundogen Brand of Spironolactone
NCGC00164397-01
 
NCGC00164397-02
NSC 150399
NSC150399
Nefurofan
Novo Spiroton
Novo-Spiroton
NovoSpiroton
Novopharm Brand of Spironolactone
Osyrol
Pfizer Brand of Spironolactone
Pharmafrid Brand of Spironolactone
Practon
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Roche Brand of Spironolactone
S0260
S3378_SIGMA
SAM002264648
SC 9420
SC-9420
SC9420
SMR000471892
SNL
SPBio_002115
Sagisal
Searle Brand of Spironolactone
Sincomen
Spiractin
Spiresis
Spiretic
Spiridon
Spiro L.U.T.
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro-Tablinen
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spirobeta
Spiroctan
Spiroctanie
Spiroderm
Spirogamma
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spirono Isis
Spirono-Isis
Spironocompren
Spironolactone
Spironolactone (JP15/USP/INN)
Spironolactone A
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactonum
Spironolactonum [INN-Latin]
Spironolattone
Spironolattone [DCIT]
Spironone
Spirospare
Sprioderm
Supra-puren
Suracton
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Worwag Brand of Spironolactone
Xenalon
ZINC03861599
betapharm Brand of Spironolactone
ct Arzneimittel Brand of Spironolactone
ct-Arzneimittel Brand of Spironolactone
spiro von ct
spironolactone
spironolattone
von ct, spiro
2
EplerenoneapprovedPhase 396107724-20-9150310, 443872
Synonyms:
107724-20-9
7alpha-methoxycarbonyl-3-oxo-9,11alpha-epoxy-17alpha-pregn-4-ene-21,17-carbolactone
AC-4213
AC1L9FDC
C12512
CGP-30083
CHEBI:31547
CHEBI:726453
CHEMBL1095097
CID443872
D01115
Eplerenone
 
Eplerenone (JAN/USAN/INN)
Epoxymexrenone
Inspra
Inspra (TN)
Inspra, Epoxymexrenone, CGP30083, SC-66110,Eplerenone
MolPort-003-986-216
NCGC00159559-01
NCGC00159559-02
S1707_Selleck
SC-66110
Selara
TL8000270
ZINC03985982
3MineralocorticoidsPhase 3367
4Natriuretic AgentsPhase 31697
5diureticsPhase 31418
6Mineralocorticoid Receptor AntagonistsPhase 3346
7Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 313168
8Diuretics, Potassium SparingPhase 31917
9Hormone AntagonistsPhase 313180
10HormonesPhase 314415
11
LenograstimapprovedPhase 21220135968-09-1
Synonyms:
G-CSF (CHO cell derived)
Glycosylated recombinant G-CSF
Glycosylated recombinant granulocyte colony stimulating factor
 
Granulocyte colony stimulating factor 3 (CHO cell derived)
Granulocyte colony-stimulating factor lenograstim
Lenograstim (genetical recombination)
Lenograstim rDNA
12Adjuvants, ImmunologicPhase 22554
13
Remifentanilapproved471132875-61-760815
Synonyms:
1-Piperidinepropanoic acid, 4-(methoxy-carbonyl)-4-((1-oxopropyl)phenylamino)-, methyl ester
132539-07-2 (mono-hydrochloride)
132875-61-7
3-(4-methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic acid methyl ester
4-carboxy-4-(n-phenylpropionamido)-1-piperidinepropionic acid dimethyl ester
AC1L1TZ8
AC1Q5ZGR
BIDD:GT0029
C08021
CHEBI:8802
CHEMBL1005
CID60815
D08473
DB00899
 
DEA No. 9739
GI 87084B
GI 87084X
GI87084B
L001266
LS-115982
MolPort-004-286-006
REMIFENTANIL
Remifentanil (INN)
Remifentanil [INN:BAN]
Remifentanyl
UNII-P10582JYYK
Ultiva
Ultiva (TN)
methyl 1-(3-methoxy-3-oxopropyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
14Hypnotics and Sedatives2616
15Narcotics3646
16Peripheral Nervous System Agents23689
17Central Nervous System Depressants13403
18Anesthetics, Intravenous2538
19Analgesics, Opioid3238
20Anesthetics9596
21Anesthetics, General2934
22Analgesics11733

Interventional clinical trials:

idNameStatusNCT IDPhase
1PHOspholamban RElated CArdiomyopathy STudy - InterventionRecruitingNCT01857856Phase 3
2Registry of Unexplained Cardiac ArrestRecruitingNCT00292032Phase 3
3Bone Marrow Derived Adult Stem Cells for Dilated CardiomyopathyCompletedNCT01302171Phase 2
4Remifentanil Intravenous Patient Controlled Analgesia (IVPCA) for Ablation of Idiopathic Ventricular TachycardiaCompletedNCT01901575
5EGM Analysis in Idiopathic Outflow Tract Ventricular ArrhythmiaCompletedNCT02722577
6Idiopathic Reactive Hypoglycaemia and Treatment With Fructo-OligosaccharideCompletedNCT00802971
7Zero-fluoroscopic Ablation Versus Conventional Fluoroscopic Ablation for the Treatment of Ventricular ArrhythmiasRecruitingNCT03041519
8Calmodulin Gene Mutations in Patients With Ventricular Arrhythmia of Unknown Origin - A Screening StudyNot yet recruitingNCT01947543
9Stereotaxis Idiopathic Ventricular Tachycardia (VT) StudyTerminatedNCT01401608

Search NIH Clinical Center for Ventricular Tachycardia, Idiopathic

Genetic Tests for Ventricular Tachycardia, Idiopathic

About this section

Genetic tests related to Ventricular Tachycardia, Idiopathic:

id Genetic test Affiliating Genes
1 Familial Ventricular Tachycardia27

Anatomical Context for Ventricular Tachycardia, Idiopathic

About this section

Publications for Ventricular Tachycardia, Idiopathic

About this section

Variations for Ventricular Tachycardia, Idiopathic

About this section

Expression for genes affiliated with Ventricular Tachycardia, Idiopathic

About this section
Search GEO for disease gene expression data for Ventricular Tachycardia, Idiopathic.

Pathways for genes affiliated with Ventricular Tachycardia, Idiopathic

About this section

GO Terms for genes affiliated with Ventricular Tachycardia, Idiopathic

About this section

Sources for Ventricular Tachycardia, Idiopathic

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet