Ventricular Tachycardia, Idiopathic malady

MalaCards: Ventricular Tachycardia, Idiopathic, also known as tachycardia, ventricular, is related to catecholaminergic polymorphic ventricular tachycardia and ventricular tachycardia. An important gene associated with Ventricular Tachycardia, Idiopathic is GNAI2 (guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2). The drugs epinephrine hydrochloride and metoprolol have been mentioned in the context of this disorder.

OMIM: 192605

ventricular tachycardia, idiopathic 33 tachycardia, ventricular 43

Diseases related to ventricular tachycardia, idiopathic by text searches and GeneDecks gene sharing:

id	Related Disease	Score	Top Affiliating Genes
1	catecholaminergic polymorphic ventricular tachycardia	8.3
2	ventricular tachycardia	7.9
3	casq2-related catecholaminergic polymorphic ventricular tachycardia	6.5
4	catecholaminergic polymorphic ventricular tachycardia multi-gene panels	6.5
5	ryr2-related catecholaminergic polymorphic ventricular tachycardia	6.5
6	ventricular tachycardia, catecholaminergic polymorphic, 2	6.5
7	ventricular tachycardia, catecholaminergic polymorphic, 1	6.5

Clinical features from OMIM: 192605

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 acebutolol, acebutolol hydrochloride, atenolol, bretylium, bretylium tosylate, edta, edta tetrasodium, epinephrine, epinephrine bitartrate, epinephrine hydrochloride, epinephrine,racemic hydrochloride, epinephryl borate, esmolol, esmolol hydrochloride, flecainide, flecainide acetate, lidocaine, lidocaine hcl pwdr [va product], lidocaine hydrochloride, lidocaine pwdr [va product], metoprolol, metoprolol succinate, metoprolol tartrate, moricizine, moricizine hydrochloride, procainamide, procainamide hydrochloride, propranolol, propranolol hydrochloride, sotalol, sotalol hydrochloride, vasopressin, vasopressin tannate (in oil)

Genes related to ventricular tachycardia, idiopathic according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	11.0	Disorders