MCID: VRN004
MIFTS: 48

Vernal Keratoconjunctivitis malady

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Vernal Keratoconjunctivitis

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Sources:
46NIH Rare Diseases, 52Orphanet, 48Novoseek, 66UMLS, 67UMLS via Orphanet, 29ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Vernal Keratoconjunctivitis:

Name: Vernal Keratoconjunctivitis 46 52
Keratoconjunctivitis, Vernal 66
Keratoconjunctivitis Vernal 48
 
Spring Catarrh 52
Vkc 46

Characteristics:

Orphanet epidemiological data:

52
vernal keratoconjunctivitis:
Inheritance: Not applicable; Age of onset: Childhood; Age of death: normal life expectancy

Classifications:

Orphanet: 52 
Rare eye diseases


External Ids:

Orphanet52 ORPHA70476
UMLS via Orphanet67 C0022577
ICD10 via Orphanet29 H16.2

Summaries for Vernal Keratoconjunctivitis

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NIH Rare Diseases:46 Vernal keratoconjunctivitis (vkc) is a chronic, severe allergy that affects the surfaces of the eyes. it most commonly occurs in boys living in warm, dry climates. attacks associated with vkc are common in the spring (hence the name "vernal") and summer but often reoccur in the winter. signs and symptoms usually begin before 10 years of age and may include hard, cobblestone-like bumps (papillae) on the upper eyelid; sensitivity to light; redness; sticky mucus discharge; and involuntary blinking or spasms of the eyelid (blepharospasm). the condition usually subsides at the onset of puberty. it is caused by a hypersensitivity (allergic reaction) to airborne-allergens. management focuses on preventing "flare ups" and relieving the symptoms of the condition. last updated: 12/7/2011

MalaCards based summary: Vernal Keratoconjunctivitis, also known as keratoconjunctivitis, vernal, is related to keratoconjunctivitis and papillary conjunctivitis. An important gene associated with Vernal Keratoconjunctivitis is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways are TSLP Signaling Pathway and Immune response_MIF-mediated glucocorticoid regulation. Affiliated tissues include eye, testes and neutrophil, and related mouse phenotypes are neoplasm and digestive/alimentary.

Wikipedia:69 Vernal keratoconjunctivitis (VKC) or spring catarrh is a recurrent, bilateral, and self-limiting... more...

Related Diseases for Vernal Keratoconjunctivitis

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Diseases related to Vernal Keratoconjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 216)
idRelated DiseaseScoreTop Affiliating Genes
1keratoconjunctivitis32.0IL4, IL5, RNASE3
2papillary conjunctivitis30.4CCL11, IL4, RNASE3
3atopy29.9CCL11, IL4, IL5, RNASE3
4uveitis29.4CCL2, ICAM1, TGFB1
5asthma27.4CCL11, ICAM1, IL4, IL5, IL6, RNASE3
6merkel cell carcinoma10.6IL5, RNASE3
7giant ganglionic hyperplasia10.6CCL11, IL5
8hypotrichosis simplex10.6IL5, RNASE3
9orbital plasma cell granuloma10.6IL5, RNASE3
10solitary cyst of breast10.6CCL11, IL5
11granulomatous endometritis10.6IL5, RNASE3
12antley-bixler syndrome with genital anomalies and disordered steroidogenesis10.6CCL11, IL5
13mixed connective tissue disease10.6IL5, RNASE3
14aortic arch interruption10.5IL5, IL6
15tarsal tunnel syndrome10.5IL5, IL6
16conjunctivitis10.5
17angioma hereditary neurocutaneous10.5IL5, IL6
18keratoconus10.4
19queensland tick typhus10.4IL5, IL6
20allergic conjunctivitis10.4
21non-gestational choriocarcinoma10.4CCL11, CCL2
22paratyphoid fever10.4IL5, RNASE3
23cytomegalovirus retinitis10.4CCL2, ICAM1
24idiopathic neutropenia10.4IL5, IL6
25arteriolosclerosis10.4ICAM1, IL6
26urinary bladder cancer10.4ICAM1, IL6
27radioulnar synostosis retinal pigment abnormalities10.4IL5, RNASE3
28fungal gastritis10.4CCL11, IL5, RNASE3
29retroperitoneal cancer10.3CCL11, IL5, RNASE3
30antigen-peptide-transporter 2 deficiency10.3CCL2, IL6
31keratitis10.3
32papillary squamous carcinoma10.3IL4, IL5
33myositis fibrosa10.3IL4, IL5
34intracranial hypertension10.3CCL11, IL4
35acute conjunctivitis10.3IL4, IL5
36glucose intolerance10.3IL4, IL5
37ileitis10.3ICAM1, IL4
38histoplasmosis10.3CCL2, IL6
39cerebellopontine angle primitive neuroectodermal10.3CCL2, IL6
40gasserian ganglion meningioma10.3CCL2, IL6
41autoimmune neuropathy10.3ICAM1, IL5, RNASE3
42sterility due to immotile flagella10.3CCL2, IL6
43benign fibrous mesothelioma10.3IL4, IL5
44cysticercosis10.3ICAM1, IL4
45bolivian hemorrhagic fever10.2CXCR3, ICAM1
46adenomatoid tumor10.2IL4, IL5
47skin disease10.2IL5, IL6, RNASE3
48african histoplasmosis10.2IL4, IL5
49congenital disorder of glycosylation, type ih10.2CCL11, IL6, RNASE3
50spermatic cord cancer10.2IL4, IL5

Graphical network of the top 20 diseases related to Vernal Keratoconjunctivitis:



Diseases related to vernal keratoconjunctivitis

Symptoms for Vernal Keratoconjunctivitis

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Drugs & Therapeutics for Vernal Keratoconjunctivitis

About this section

Drugs for Vernal Keratoconjunctivitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DexamethasonePhase 4200150-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
2
Histamine PhosphatePhase 4, Phase 3100851-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
 
EINECS 200-118-4
H0147
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
3
TacrolimusPhase 4, Phase 3, Phase 21058104987-11-3445643, 439492
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
Anhydrous tacrolimus
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
 
FR900506
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus anhydrous
Tacrolimus hydrate
Tacrolimus, anhydrous
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
4
protease inhibitorsPhase 45157
Synonyms:
 
protease inhibitors
5
histaminePhase 4, Phase 3100975614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
6
MiconazolePhase 4, Phase 3, Phase 2357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
7Dexamethasone acetatePhase 420011177-87-3
8glucocorticoidsPhase 44756
9
PseudoephedrinePhase 3, Phase 256990-82-47028
Synonyms:
( )-Pseudoephedrine
(+)-(1S,2S)-Pseudoephedrine
(+)-Pseudoephedrine
(+)-Psi-ephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(1S,2S)-(+)-Pseudoephedrine
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
(1S,2S)-2-Methylamino-1-phenyl-1-propanol
(1S,2S)-Pseudoephedrine
(1S,2S)-Pseudoephedrine, polymer-bound
1-Ephedrine
2-(Methylamino)-1-phenyl-1-propanol
287636_ALDRICH
304-87-0
30987-59-8
37577-31-4
649031_ALDRICH
90-82-4
AC-20292
AC1L1NUA
Acunaso
Acunaso (TN)
Afrinol
BIDD:GT0817
BRD-K84175871-003-02-2
BSPBio_003261
Balminil Decongestant Syrup
Benylin Decongestant
Benzenemethanol, alpha-((1S)-1-(methylamino)ethyl)-, (alpha-S)- (9CI)
Besan
C02765
C10H15NO
CHEBI:51209
CHEMBL1590
CID7028
CPD-9954
Cenafed
D-Isoephedrine
D-Pseudoephedrine
D-Pseudoephedrine base
D-Psi-2-Methylamino-1-phenyl-1-propanol
D-Psi-2-methylamino-1-phenyl-1-propanol
D-Psi-Ephedrine
D-Psi-ephedrine
D08449
DB00852
Decofed
Dimetapp Decongestant
Dimetapp Decongestant Pediatric Drops
DivK1c_000451
Drixoral N.D.
Drixoral Nasal Decongestant
EINECS 202-018-6
Efidac 24 Pseudoephedrine Hcl
Efidac/24
Eltor 120
Ephedrine
Genaphed
HSDB 3177
I01-8928
IDI1_000451
 
Isoephedrine
KBio1_000451
KBio2_001358
KBio2_003926
KBio2_006494
KBio3_002762
KBioGR_001763
KBioSS_001358
L(+)-Psi-Ephedrine
L(+)-Psi-ephedrine
L(+)-psi-Ephedrine
L-(+)-Pseudoephedrine
LS-125922
Lopac-E-3250
Maxenal
MolPort-001-684-474
Myfedrine
NCGC00015408-01
NCGC00178180-01
NCI60_002955
NINDS_000451
Neodurasina
Neodurasina (TN)
Novafed
PDSP1_001347
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoefedrina [INN-Spanish]
Pseudoephedrine
Pseudoephedrine (D)
Pseudoephedrine (INN)
Pseudoephedrine D-form
Pseudoephedrine Ephedrine
Pseudoephedrine [INN:BAN]
Pseudoephedrine d-form
Pseudoephedrinum
Pseudoephedrinum [INN-Latin]
Psi-ephedrin
Psi-ephedrine
Robidrine
SPBio_001365
STOCK1N-42675
Spectrum2_001303
Spectrum3_001771
Spectrum4_001162
Spectrum5_000650
Spectrum_000878
Sudafed
Sudafed Decongestant
Sudafed Decongestant 12 Hour
Sudafed Decongestant Extra Strength
Triaminic AM Decongestant Formula
Triaminic Infant Oral Decongestant Drops
UNII-7CUC9DDI9F
alpha-(1-(Methylamino)ethyl)benzyl alcohol
d-Isoephedrine
d-Pseudoephedrine
d-psi-2-Methylamino-1-phenyl-1-propanol
d-psi-Ephedrine
trans-Ephedrine
10
EphedrinePhase 3, Phase 2569299-42-39294
Synonyms:
( )-Pseudoephedrine
(+)-Ephedrin
(+)-Ephedrine
(+)-Pseudoephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(+-)-Ephedrine
(-)-Ephedrine
(-)-Pseudoephedrine
(-)-psi-Ephedrine
(-)-threo-Ephedrine
(1R,2R)-Ephedrine
(1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane
(1S,2R)-Ephedrine
(L)-EPHEDRINE
--EPHEDRINE
1-EPHEDRINE
1-Sedrin
134910_ALDRICH
287636_ALDRICH
287644_ALDRICH
299-42-3
304-87-0
30987-59-8
321-96-0
321-97-1
321-98-2
37577-31-4
38732-95-5
45261_FLUKA
4607-45-8
50-98-6
50906-05-3
53214-57-6
649031_ALDRICH
6912-63-6
7009-81-6
90-82-4
968-63-8
AC-20231
AC-20292
AC1L1JGK
AC1L1NUA
AC1L1RFA
AC1L1SR1
AC1L1T31
AC1L1Y3M
AC1O8JUO
AC1Q3XJE
AC1Q3XJM
AC1Q3XJN
AC1Q59F5
AC1Q7701
AI3-02761
AKOS000268842
AR-1A0126
AR-1I7143
Acunaso
Acunaso (TN)
Afrinol
Ambap299-42-3
BIDD:GT0817
BRN 3197916
BRN 4231286
BSPBio_001946
BSPBio_001968
BSPBio_003261
Benylin Decongestant
Besan
Biophedrin
C01575
C02765
C10H15NO
CHEBI:15407
CHEBI:51209
CHEMBL1590
CHEMBL211456
CHEMBL357080
CID11972440
CID5032
CID62946
CID6710657
CID7028
CID8650
CID9294
CID9457
CPD-9954
CPDD 0049
Cenafed
D00124
D08449
DB00852
DB01364
Decofed
DivK1c_000181
DivK1c_000451
DivK1c_000461
Drixoral N.D.
EINECS 202-017-0
EINECS 202-018-6
EINECS 206-080-5
EINECS 206-292-8
EINECS 206-293-3
Eciphin
Efedrin
Efidac/24
Eltor 120
Ephedral
Ephedremal
Ephedrin
Ephedrine
Ephedrine (TN)
Ephedrine (USP)
Ephedrine [USAN:BAN]
Ephedrine l-form
Ephedrital
Ephedrol
Ephedrosan
Ephedrotal
Ephedsol
Ephendronal
Ephoxamin
Fedrin
Genaphed
HSDB 3072
HSDB 3177
I-Sedrin
I01-3584
I01-8925
I01-8928
 
IDI1_000181
IDI1_000451
IDI1_000461
Isoephedrine
Jsp005664
KBio1_000181
KBio1_000451
KBio1_000461
KBio2_001358
KBio2_001500
KBio2_003926
KBio2_004068
KBio2_006494
KBio2_006636
KBio3_001188
KBio3_001446
KBio3_002762
KBioGR_001013
KBioGR_001763
KBioSS_001358
KBioSS_001500
KST-1A9168
Kratedyn
L(+)-psi-Ephedrine
L(-)-Ephedrine
L-(+)-Ephedrine
L-(-)-Ephedrine
L-Ephedrine
L-erythro-2-(Methylamino)-1-phenylpropan-1-ol
L000968
LS-125921
LS-125922
LS-43083
LS-63961
LS-63962
LS-63963
LS-63964
Lexofedrin
Lopac-E-3250
Lopac0_000501
MLS000069657
Manadrin
Mandrin
Maxenal
MolPort-001-684-474
MolPort-001-684-477
MolPort-001-684-478
MolPort-001-684-479
MolPort-001-769-085
Myfedrine
NCGC00015408-01
NCGC00015408-02
NCGC00162174-01
NCGC00178180-01
NCGC00178889-01
NCI-C55652
NCI60_002955
NINDS_000181
NINDS_000451
NINDS_000461
NSC 165609
NSC 170951
NSC 8971
NSC165609
NSC170951
NSC8971
Nasol
Neodurasina
Neodurasina (TN)
Oprea1_287330
PDSP1_000168
PDSP1_001106
PDSP1_001343
PDSP1_001345
PDSP1_001346
PDSP1_001347
PDSP2_000167
PDSP2_001090
PDSP2_001327
PDSP2_001329
PDSP2_001330
PDSP2_001331
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoephedrine (D)
Pseudoephedrinum
Psi-ephedrin
Psi-ephedrine
Robidrine
SMR000059174
SPBio_000214
SPBio_001365
SPBio_001377
ST023802
STK367993
STOCK1N-42675
Sanedrine
Spectrum2_000137
Spectrum2_001303
Spectrum2_001309
Spectrum3_000414
Spectrum3_000563
Spectrum3_001771
Spectrum4_000497
Spectrum4_001162
Spectrum5_000650
Spectrum5_000879
Spectrum5_001106
Spectrum_000878
Spectrum_001020
Sudafed
Sudafed Decongestant
UNII-03VRY66076
UNII-7CUC9DDI9F
UNII-GN83C131XS
Vencipon
WLN: QYR & Y1 & M1
WLN: QYR&Y1&M1
Zephrol
d-Ephedrine
d-Isoephedrine
d-Pseudoephedrine
d-psi-Ephedrine
l-Ephedrine
l-Pseudoephedrine
racephedrine
trans-Ephedrine
11
KetotifenPhase 32134580-14-8, 34580-13-73827
Synonyms:
10H-Benzo[4,5]cyclohepta[1,2-b]thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, (2E)-2-butenedioate (1:1)
116655-74-4
34580-13-7
4,9-Dihydro-4-(1-methyl-4-piperidinylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophen-10-one
4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one
4-(1-Methyl-4-piperidylidene)-9-hydrobenzo[a]thiopheno[3,2-d][7]annulen-10-one
4-(1-Methyl-piperidin-4-ylidene)-4,9-dihydro-1-thia-benzo[f]azulen-10-one
4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
AB00053575
AC-15945
AC1L1GSZ
AKOS000541268
Alaway (TN)
BAS 00444483
BIDD:GT0509
BPBio1_000575
BRD-K28936863-051-05-8
BRN 3983897
BSPBio_000521
BSPBio_002964
C19H19NOS
CAS-34580-14-8
CHEBI:112957
CHEMBL534
CID3827
D08105
DB00920
DivK1c_000111
EINECS 252-099-7
HC 20-511
HMS2090F16
HSDB 7283
IDI1_000111
KBio1_000111
KBio2_000906
KBio2_003474
KBio2_006042
KBio3_002184
KBioGR_001289
KBioSS_000906
Ketotifen (INN)
Ketotifen Fumarate
 
Ketotifen [INN:BAN]
Ketotifene
Ketotifene [INN-French]
Ketotifene fumarate
Ketotifeno
Ketotifeno [INN-Spanish]
Ketotifenum
Ketotifenum [INN-Latin]
Ketotifin
Ketotiphen
Ketotiphene
L000753
LS-33820
Lopac-K-2628
Lopac0_000706
MolPort-001-933-278
NCGC00015580-01
NCGC00015580-02
NCGC00015580-03
NCGC00015580-09
NCGC00022572-02
NCGC00022572-04
NCGC00022572-05
NINDS_000111
Oprea1_335550
Oprea1_553550
Prestwick0_000371
Prestwick1_000371
Prestwick2_000371
Prestwick3_000371
SPBio_001275
SPBio_002442
STK048448
STOCK1S-14132
Spectrum2_001198
Spectrum3_001382
Spectrum4_000805
Spectrum5_001395
Spectrum_000426
Tocris-0784
UNII-X49220T18G
Zaditor
ketotifen
12ACIDOPHILUSNutraceuticalPhase 2, Phase 3502

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1Topical Cyclosporine for Vernal Keratoconjunctivitis (VKC) in RwandaCompletedNCT01211327Phase 4
2Study of the Clinical and Biological Efficacity of NAAXIA SINE® in Vernal KeratoconjunctivitisCompletedNCT00357019Phase 4
3Topical Tacrolimus in Vernal KeratoconjunctivitisRecruitingNCT02456025Phase 4
4Cyclosporin A Eye Drop Treatment in Vernal KeratoconjunctivitisCompletedNCT00426023Phase 3
5Lactobacillus Rhamnosus GG Oral Treatment Efficacy on Vernal Keratoconjunctivitis TreatmentCompletedNCT00445120Phase 2, Phase 3
6Phase III Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal KeratoconjunctivitisCompletedNCT00567762Phase 3
7Phase III, Long-Term, Open-Label, Extension Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal KeratoconjunctivitisCompletedNCT00567918Phase 3
8Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis (VKC)CompletedNCT00328653Phase 2, Phase 3
9Efficacy Study of FK-506 and Cyclosporine in Vernal Keratoconjunctivits (VKC)CompletedNCT01068054Phase 2, Phase 3
10Double-Masked Trial of NOVA22007 (1mg/mL Ciclosporin/Cyclosporine) Versus Vehicle in Pediatric Patients With Active Severe Vernal KeratoconjunctivitisActive, not recruitingNCT01751126Phase 3
11Cytokine Assay in Tears of Healthy Children and With Vernal Keratoconjunctivitis: Case Control Study and Monitoring of Cases at 6 MonthsRecruitingNCT02057822

Search NIH Clinical Center for Vernal Keratoconjunctivitis

Genetic Tests for Vernal Keratoconjunctivitis

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Anatomical Context for Vernal Keratoconjunctivitis

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MalaCards organs/tissues related to Vernal Keratoconjunctivitis:

34
Eye, Testes, Neutrophil, T cells, Thyroid

Animal Models for Vernal Keratoconjunctivitis or affiliated genes

About this section

MGI Mouse Phenotypes related to Vernal Keratoconjunctivitis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020067.8CXCR3, ICAM1, IL5, IL6, TGFB1
2MP:00053817.8ICAM1, IL4, IL5, IL6, TGFB1
3MP:00053887.3CCL11, CXCR3, IL4, IL5, IL6, TGFB1
4MP:00053976.6CCL11, CXCR3, ICAM1, IL4, IL5, IL6
5MP:00053876.6CCL11, CCL2, CXCR3, ICAM1, IL4, IL5

Publications for Vernal Keratoconjunctivitis

About this section

Articles related to Vernal Keratoconjunctivitis:

(show top 50)    (show all 311)
idTitleAuthorsYear
1
Omalizumab Treatment of Vernal Keratoconjunctivitis. (26795360)
2016
2
Tacrolimus Ointment for Treatment of Vernal Keratoconjunctivitis. (26957853)
2016
3
Quiescent and Active Tear Protein Profiles to Predict Vernal Keratoconjunctivitis Reactivation. (26989694)
2016
4
New Finding in Vernal Keratoconjunctivitis: Splendore-Hoeppli Phenomenon. (27027918)
2016
5
Vernal Keratoconjunctivitis and immune-mediated diseases: One unique way to symptom control? (25692810)
2015
6
Intracellular IL-4, IL-5, and IFN-I^ as the main characteristic of CD4+CD30+ T cells after allergen stimulation in patients with vernal keratoconjunctivitis. (25999672)
2015
7
In vivo confocal microscopy of meibomian glands and palpebral conjunctiva in vernal keratoconjunctivitis. (26044472)
2015
8
Sex hormones in allergic conjunctivitis: altered levels of circulating androgens and estrogens in children and adolescents with vernal keratoconjunctivitis. (25756057)
2015
9
Increased incidence of thyroid dysfunction and autoimmunity in patients with vernal keratoconjunctivitis. (25140177)
2014
10
Vernal keratoconjunctivitis with giant papillae on the inferior tarsal conjunctiva. (24240487)
2014
11
Severe vernal keratoconjunctivitis successfully treated with subcutaneous omalizumab. (23607979)
2013
12
Vernal keratoconjunctivitis: an update. (23038763)
2013
13
Vernal keratoconjunctivitis: atopy and autoimmunity. (23740459)
2013
14
Vernal keratoconjunctivitis in school children in Rwanda and its association with socio-economic status: a population-based survey. (21976577)
2011
15
Vernal keratoconjunctivitis with limbal stem cell deficiency. (21598432)
2011
16
Vernal keratoconjunctivitis: a major review. (18786127)
2009
17
Efficacy of topical cyclosporin A 0.05% in conjunctival impression cytology specimens and clinical findings of severe vernal keratoconjunctivitis in children. (18991035)
2008
18
Natural killer cells in vernal keratoconjunctivitis. (17893656)
2007
19
Clinical and biological efficacy of preservative-free NAAGA eye-drops versus levocabastine eye-drops in vernal keratoconjunctivitis patients. (17585003)
2007
20
Systematic review and meta-analysis of randomised clinical trials on topical treatments for vernal keratoconjunctivitis. (17588996)
2007
21
Vernal keratoconjunctivitis: modes of presentation in Nepalese population. (18604088)
2007
22
Vernal keratoconjunctivitis presenting unilaterally. (16761642)
2006
23
Immunopathogenesis of conjunctival remodelling in vernal keratoconjunctivitis. (15746957)
2006
24
Low dose mitomycin-C in severe vernal keratoconjunctivitis: a randomized prospective double blind study. (16770028)
2006
25
Atopy and serum eosinophil cationic protein in 110 white children with vernal keratoconjunctivitis: differences between tarsal and limbal forms. (12614446)
2003
26
Surgical treatment of limbal vernal keratoconjunctivitis by resection of a limbal lesion. (12543198)
2002
27
Cytokine mRNA expression in vernal keratoconjunctivitis]. (12187821)
2002
28
Langerhans' cells in vernal keratoconjunctivitis express the costimulatory molecule B7-2 (CD86), but not B7-1 (CD80). (11702979)
2001
29
Cyclosporine effects on clinical findings and impression cytology specimens in severe vernal keratoconjunctivitis. (11399937)
2001
30
Incidence of keratoconus in subjects with vernal keratoconjunctivitis: a videokeratographic study. (11305286)
2001
31
Respiratory syncytial virus and chlamydia are not detectable by PCR in ongoing vernal keratoconjunctivitis. (11935435)
2001
32
A randomized trial of low-dose, topical mitomycin-C in the treatment of severe vernal keratoconjunctivitis. (10690822)
2000
33
Nedocromil sodium eye drops are more effective than sodium cromoglycate eye drops for the long-term management of vernal keratoconjunctivitis. (10202368)
1999
34
Vernal keratoconjunctivitis in a Stockholm ophthalmic centre--epidemiological, functional, and immunologic investigations. (10551301)
1999
35
Serum levels of soluble intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and interleukin-2 receptor in patients with vernal keratoconjunctivitis and allergic conjunctivitis. (10221436)
1999
36
Effects of lodoxamide, disodium cromoglycate and fluorometholone on tear leukotriene levels in vernal keratoconjunctivitis. (9683957)
1998
37
Topical cyclosporin A 2% in the treatment of vernal keratoconjunctivitis. (9246280)
1997
38
Lodoxamide in vernal keratoconjunctivitis. (8740338)
1996
39
Efficacy of lodoxamide 0.1% versus N-acetyl aspartyl glutamic acid 6% ophthalmic solutions in patients with vernal keratoconjunctivitis. (8792357)
1996
40
Increased plasma levels of nerve growth factor in vernal keratoconjunctivitis and relationship to conjunctival mast cells. (7657550)
1995
41
Topical flurbiprofen therapy in vernal keratoconjunctivitis. (8906937)
1995
42
Collagen types I and III in giant papillae of vernal keratoconjunctivitis. (7612563)
1995
43
Eosinophil cationic protein in tears of normal subjects and patients affected by vernal keratoconjunctivitis. (8588697)
1995
44
Lodoxamide for vernal keratoconjunctivitis. (8121328)
1994
45
Efficacy of lodoxamide 0.1% ophthalmic solution in resolving corneal epitheliopathy associated with vernal keratoconjunctivitis. (8154531)
1994
46
Treatment of vernal keratoconjunctivitis a double-masked study. (22822779)
1993
47
Treatment of vernal keratoconjunctivitis: a retrospective clinical case study. Wallace F. Molinari Ocular Pharmacology Award. (1923330)
1991
48
Conjunctival deposition of eosinophil granule major basic protein in vernal keratoconjunctivitis and contact lens-associated giant papillary conjunctivitis. (2750834)
1989
49
Limbal vernal keratoconjunctivitis with a hypertrophic limbal mass lesion. (3566030)
1987
50
Vernal keratoconjunctivitis and keratoconus. (6846462)
1983

Variations for Vernal Keratoconjunctivitis

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Expression for genes affiliated with Vernal Keratoconjunctivitis

About this section
Search GEO for disease gene expression data for Vernal Keratoconjunctivitis.

Pathways for genes affiliated with Vernal Keratoconjunctivitis

About this section

Pathways related to Vernal Keratoconjunctivitis according to GeneCards Suite gene sharing:

(show all 42)
idSuper pathwaysScoreTop Affiliating Genes
19.7CCL11, IL6
29.6ICAM1, IL6
39.6ICAM1, IL6
49.6CCL11, CXCR3
59.6CCL11, CCL2
69.5CCL2, ICAM1
79.5CCL2, IL6
89.5IL4, IL5
99.5IL4, IL5
109.1CCL11, IL4, IL5
119.1CCL11, IL4, IL5
129.1CCL2, ICAM1, IL6
13
Show member pathways
9.1CCL2, ICAM1, IL6
14
Show member pathways
9.1CCL11, CCL2, CXCR3
15
Show member pathways
9.1CCL11, IL4, IL6
169.0IL4, TGFB1
17
Show member pathways
9.0IL4, IL5, IL6
189.0IL4, IL5, IL6
19
Show member pathways
9.0IL4, IL5, IL6
209.0IL4, IL5, IL6
219.0CXCR3, IL4, IL5
22
Show member pathways
8.8ICAM1, IL6, TGFB1
238.6ICAM1, IL4, IL5, IL6
24
Show member pathways
8.6IL4, IL6, TGFB1
25
Show member pathways
8.5CCL2, ICAM1, IL4, IL6
268.3CCL2, ICAM1, IL6, TGFB1
278.3CCL2, ICAM1, IL6, TGFB1
288.3CCL2, ICAM1, IL6, TGFB1
298.2IL4, IL5, IL6, TGFB1
30
Show member pathways
8.2IL4, IL5, IL6, TGFB1
318.2IL4, IL5, IL6, TGFB1
328.2CCL11, CCL2, IL4, IL5, IL6
33
Show member pathways
7.9CCL11, CCL2, CXCR3, ICAM1, TGFB1
347.8ICAM1, IL4, IL5, IL6, TGFB1
357.6CCL2, ICAM1, IL4, IL6, TGFB1
36
Show member pathways
7.3CCL11, CCL2, IL4, IL5, IL6, TGFB1
37
Show member pathways
7.1CCL11, ICAM1, IL4, IL5, IL6, RNASE3
38
Show member pathways
6.9CCL11, CCL2, ICAM1, IL4, IL5, IL6
39
Show member pathways
6.8CCL11, CCL2, CXCR3, IL4, IL5, IL6
40
Show member pathways
6.8CCL11, CCL2, CXCR3, IL4, IL5, IL6
41
Show member pathways
6.8CCL11, CCL2, CXCR3, IL4, IL5, IL6
42
Show member pathways
6.8CCL11, CCL2, CXCR3, IL4, IL5, IL6

GO Terms for genes affiliated with Vernal Keratoconjunctivitis

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Cellular components related to Vernal Keratoconjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.8CXCR3, ICAM1, IL4, IL6
2extracellular regionGO:00055767.3CCL11, CCL2, IL5, IL6, RNASE3, TGFB1
3extracellular spaceGO:00056156.6CCL11, CCL2, ICAM1, IL4, IL5, IL6

Biological processes related to Vernal Keratoconjunctivitis according to GeneCards Suite gene sharing:

(show all 46)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of immunoglobulin secretionGO:005102410.4IL5, IL6
2cellular response to nutrient levelsGO:003166910.3ICAM1, IL6
3positive regulation of cellular extravasationGO:000269310.2CCL2, ICAM1
4lymphocyte chemotaxisGO:004824710.2CCL11, CCL2
5regulation of vascular endothelial growth factor productionGO:001057410.2CCL2, IL6
6positive regulation of JAK-STAT cascadeGO:004642710.2IL5, IL6
7negative regulation of endothelial cell apoptotic processGO:200035210.2ICAM1, IL4
8positive regulation of B cell activationGO:005087110.1IL4, IL6
9positive regulation of B cell proliferationGO:003089010.1IL4, IL5
10response to antibioticGO:004667710.1CCL2, IL6
11innate immune response in mucosaGO:000222710.0IL4, RNASE3
12defense response to protozoanGO:004283210.0IL4, IL6
13response to bacteriumGO:000961710.0CCL2, IL6
14lipopolysaccharide-mediated signaling pathwayGO:00316639.8CCL2, TGFB1
15protein kinase B signalingGO:00434919.8CCL2, TGFB1
16monocyte chemotaxisGO:00025489.8CCL11, CCL2, IL6
17positive regulation of mononuclear cell migrationGO:00716779.8IL4, TGFB1
18negative regulation of T cell activationGO:00508689.8IL4, TGFB1
19positive regulation of collagen biosynthetic processGO:00329679.7CCL2, TGFB1
20cellular response to lipopolysaccharideGO:00712229.6CCL2, ICAM1, IL6
21cytokine-mediated signaling pathwayGO:00192219.6CCL2, IL5, IL6
22chemokine-mediated signaling pathwayGO:00700989.6CCL11, CCL2, CXCR3
23myeloid dendritic cell differentiationGO:00430119.5IL4, TGFB1
24positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.5IL4, IL5, IL6
25response to lipopolysaccharideGO:00324969.5CCL2, ICAM1, IL6
26response to amino acidGO:00432009.4CCL2, ICAM1, IL6
27cellular response to interleukin-1GO:00713479.3CCL11, CCL2, ICAM1, IL6
28cellular response to tumor necrosis factorGO:00713569.3CCL11, CCL2, ICAM1, IL6
29positive regulation of NF-kappaB transcription factor activityGO:00510929.3ICAM1, IL6, TGFB1
30response to woundingGO:00096119.2CCL2, IL6, TGFB1
31regulation of cell shapeGO:00083609.2CCL11, CCL2, ICAM1, IL6
32agingGO:00075689.1CCL2, IL6, TGFB1
33positive regulation of GTPase activityGO:00435479.1CCL11, CCL2, ICAM1, IL5
34cellular response to dexamethasone stimulusGO:00715499.1CCL2, IL6, TGFB1
35cell adhesionGO:00071559.0CCL11, CCL2, CXCR3, ICAM1
36chemotaxisGO:00069358.9CCL11, CCL2, CXCR3, IL4
37response to hypoxiaGO:00016668.9CCL2, ICAM1, TGFB1
38positive regulation of ERK1 and ERK2 cascadeGO:00703748.9CCL11, CCL2, ICAM1, IL6
39response to ethanolGO:00454718.8CCL2, ICAM1, IL4
40cellular calcium ion homeostasisGO:00068748.8CCL11, CCL2, TGFB1
41response to organic cyclic compoundGO:00140708.6ICAM1, IL4, IL6, TGFB1
42positive regulation of transcription, DNA-templatedGO:00458938.6IL4, IL5, IL6, TGFB1
43positive regulation of peptidyl-tyrosine phosphorylationGO:00507318.4ICAM1, IL4, IL5, IL6, TGFB1
44positive regulation of cell proliferationGO:00082848.2IL4, IL5, IL6, TGFB1
45inflammatory responseGO:00069547.9CCL11, CCL2, CXCR3, IL5, IL6, TGFB1
46response to drugGO:00424937.7CCL2, ICAM1, IL4, IL6, TGFB1

Molecular functions related to Vernal Keratoconjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1growth factor activityGO:00080838.2IL4, IL5, IL6, TGFB1
2cytokine activityGO:00051257.4CCL2, IL4, IL5, IL6, TGFB1

Sources for Vernal Keratoconjunctivitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet