MCID: VRN004
MIFTS: 40

Vernal Keratoconjunctivitis malady

Rare diseases, Eye diseases categories

Aliases & Classifications for Vernal Keratoconjunctivitis

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Sources:
45NIH Rare Diseases, 47Novoseek, 51Orphanet, 65UMLS, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all sources

Aliases & Descriptions for Vernal Keratoconjunctivitis:

Name: Vernal Keratoconjunctivitis 45 51
Keratoconjunctivitis, Vernal 65
Keratoconjunctivitis Vernal 47
 
Spring Catarrh 51
Vkc 45


Classifications:

Orphanet: 51 
Rare eye diseases


Characteristics (Orphanet epidemiological data):

51
vernal keratoconjunctivitis:
Inheritance: Not applicable; Age of onset: Childhood; Age of death: normal life expectancy


External Ids:

Orphanet51 70476
ICD10 via Orphanet28 H16.2
UMLS via Orphanet66 C0022577

Summaries for Vernal Keratoconjunctivitis

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NIH Rare Diseases:45 Vernal keratoconjunctivitis (vkc) is a chronic, severe allergy that affects the surfaces of the eyes. it most commonly occurs in boys living in warm, dry climates. attacks associated with vkc are common in the spring (hence the name "vernal") and summer but often reoccur in the winter. signs and symptoms usually begin before 10 years of age and may include hard, cobblestone-like bumps (papillae) on the upper eyelid; sensitivity to light; redness; sticky mucus discharge; and involuntary blinking or spasms of the eyelid (blepharospasm). the condition usually subsides at the onset of puberty. it is caused by a hypersensitivity (allergic reaction) to airborne-allergens. management focuses on preventing "flare ups" and relieving the symptoms of the condition. last updated: 12/7/2011

MalaCards based summary: Vernal Keratoconjunctivitis, also known as keratoconjunctivitis, vernal, is related to conjunctivitis and atopy. An important gene associated with Vernal Keratoconjunctivitis is RNASE3 (Ribonuclease, RNase A Family, 3), and among its related pathways are Inflammatory Response Pathway and CXCR3-mediated signaling events. Affiliated tissues include eye, testes and neutrophil, and related mouse phenotypes are digestive/alimentary and respiratory system.

Wikipedia:68 Vernal keratoconjunctivitis (VKC) or Spring catarrh is a recurrent, bilateral, and self-limiting... more...

Related Diseases for Vernal Keratoconjunctivitis

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Diseases related to Vernal Keratoconjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 188)
idRelated DiseaseScoreTop Affiliating Genes
1conjunctivitis31.0CCL11, IL13, IL4, IL5, RNASE3
2atopy30.3CCL11, IL13, IL4, IL5, RNASE3
3allergic rhinitis29.4CCL11, CCL5, ICAM1, IL13, IL4, IL5
4asthma29.2CCL11, CCL5, ICAM1, IL13, IL4, IL5
5keratoconjunctivitis11.5
6allergic conjunctivitis10.9
7keratitis10.8
8giant papillary conjunctivitis10.8
9eye disease10.8
10vernal conjunctivitis10.7
11spiradenoma10.7
12conjunctival disease10.7
13corneal disease10.7
14vernal keratitis10.7
15keratoconus10.7
16drug rash with eosinophilia and systemic symptoms10.7
17globe disease10.7
18bowman's membrane folds or rupture10.5
19ocular hyperemia10.4
20conjunctival pigmentation10.4
21trachoma10.4
22allergic asthma10.4
23autonomic nervous system disease10.4
24corneal ulcer10.4
25eosinophilia10.4
26papillary conjunctivitis10.4
27steroid-induced glaucoma10.4
28atopic keratoconjunctivitis10.4
29porphyria10.3
30congenital porphyria10.3
31vascular myelopathy10.3IL5, RNASE3
32pemphigus and fogo selvagem10.2CCL11, IL5
33odontoclasia10.2IL5, RNASE3
34trichohepatoenteric syndrome 210.2
35asthma 110.2
36mucolipidosis iv10.2
37cataract 3310.2
38cataract10.2
39limbal stem cell deficiency10.2
40corneal ectasia10.2
41ocular hypertension10.2
42mooren's ulcer10.2
43atopic dermatitis10.2
44central corneal ulcer10.2
45infertility10.2
46acute conjunctivitis10.2
47amblyopia10.2
48bacterial conjunctivitis10.2
49chronic conjunctivitis10.2
50conjunctival deposit10.2

Graphical network of the top 20 diseases related to Vernal Keratoconjunctivitis:



Diseases related to vernal keratoconjunctivitis

Symptoms for Vernal Keratoconjunctivitis

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Drugs & Therapeutics for Vernal Keratoconjunctivitis

About this section

Drugs for Vernal Keratoconjunctivitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Miconazoleapproved, investigationalPhase 4, Phase 3, Phase 2291222916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
2
Histamine PhosphateapprovedPhase 4, Phase 385251-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
EINECS 200-118-4
 
H0147
Histamine Positive Skin Test Control
Histamine Positive skin test control
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
3
Dexamethasoneapproved, investigationalPhase 4180650-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Baycadron
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
Dexameth
Dexamethansone
 
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone acetate
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone sodium phosphate
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamethsone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
Ozurdex
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
4
Tacrolimusapproved, investigationalPhase 4, Phase 3, Phase 2992104987-11-3445643, 439492, 445647, 439492, 445647
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
8-DEETHYL-8-[but-3-enyl]-ascomycin
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
FR900506
 
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
Hecoria
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus Hydrate
Tacrolimus anhydrous
Tacrolimus hydrate
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
5BB 1101Phase 41848
6N-acetyl-1-aspartylglutamic acidPhase 42
7
histaminePhase 4, Phase 385275614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
8CyclosporinsPhase 4, Phase 3, Phase 2849
9Dexamethasone acetatePhase 418061177-87-3
10Dexamethasone 21-phosphatePhase 41806
11TetrahydrozolinePhase 4, Phase 3, Phase 2484
12Glutamic AcidNutraceuticalPhase 4187
13
KetotifenapprovedPhase 32034580-14-83827
Synonyms:
10H-Benzo[4,5]cyclohepta[1,2-b]thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, (2E)-2-butenedioate (1:1)
116655-74-4
34580-13-7
4,9-Dihydro-4-(1-methyl-4-piperidinylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophen-10-one
4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one
4-(1-Methyl-4-piperidylidene)-9-hydrobenzo[a]thiopheno[3,2-d][7]annulen-10-one
4-(1-Methyl-piperidin-4-ylidene)-4,9-dihydro-1-thia-benzo[f]azulen-10-one
4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
AB00053575
AC-15945
AC1L1GSZ
AKOS000541268
Alaway
Alaway (TN)
Allergy Eye
Allergy Eye Drops
Allergy Eye original prescription strength
Allergy Relief Eye
Allergy Relief Eye Drops
Antihistamine Eye
BAS 00444483
BIDD:GT0509
BPBio1_000575
BRD-K28936863-051-05-8
BRN 3983897
BSPBio_000521
BSPBio_002964
C19H19NOS
CAS-34580-14-8
CHEBI:112957
CHEMBL534
CID3827
Care One Allergy Eye
Care One Eye Itch Relief
D08105
DB00920
DivK1c_000111
EINECS 252-099-7
Equaline Eye Itch Relief
Equate Eye Itch Relief
Equate Itchy Eye
Eye Itch
Eye Itch Relief
Good Neighbor Pharmacy Eye Itch Relief
Good Neighbor Pharmacy Itchy Eye
Good Sense Allergy Eye
Good Sense Eye Itch Relief
Good Sense Itchy Eye original prescription strength
HC 20-511
HMS2090F16
HSDB 7283
Health Mart Eye Itch Relief
IDI1_000111
Itchy Eye
Itchy Eye Drops
Itchy Eye Relief
Itchy Eye original prescription strength
 
KBio1_000111
KBio2_000906
KBio2_003474
KBio2_006042
KBio3_002184
KBioGR_001289
KBioSS_000906
Ketotifen (INN)
Ketotifen Fumarate
Ketotifen [INN:BAN]
Ketotifene
Ketotifene [INN-French]
Ketotifene fumarate
Ketotifeno
Ketotifeno [INN-Spanish]
Ketotifenum
Ketotifenum [INN-Latin]
Ketotifin
Ketotiphen
Ketotiphene
L000753
LS-33820
Leader Allergy Eye
Leader Eye Itch Relief Drops
Lopac-K-2628
Lopac0_000706
MolPort-001-933-278
NCGC00015580-01
NCGC00015580-02
NCGC00015580-03
NCGC00015580-09
NCGC00022572-02
NCGC00022572-04
NCGC00022572-05
NINDS_000111
Oprea1_335550
Oprea1_553550
Prestwick0_000371
Prestwick1_000371
Prestwick2_000371
Prestwick3_000371
SPBio_001275
SPBio_002442
STK048448
STOCK1S-14132
Smart Sense Allergy
Spectrum2_001198
Spectrum3_001382
Spectrum4_000805
Spectrum5_001395
Spectrum_000426
Sunmark Eye Itch Relief
Tocris-0784
Topcare Eye Itch Relief
UNII-X49220T18G
Wal Zyr
Zaditor
Zaditor Antihistamine Eye Drops
ketotifen
14
EphedrineapprovedPhase 3438299-42-39294
Synonyms:
( )-Pseudoephedrine
(+)-Ephedrin
(+)-Ephedrine
(+)-Pseudoephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(+-)-Ephedrine
(-)-Ephedrine
(-)-Pseudoephedrine
(-)-psi-Ephedrine
(-)-threo-Ephedrine
(1R,2R)-Ephedrine
(1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane
(1S,2R)-Ephedrine
(L)-EPHEDRINE
--EPHEDRINE
1-EPHEDRINE
1-Sedrin
134910_ALDRICH
287636_ALDRICH
287644_ALDRICH
299-42-3
304-87-0
30987-59-8
321-96-0
321-97-1
321-98-2
37577-31-4
38732-95-5
45261_FLUKA
4607-45-8
50-98-6
50906-05-3
53214-57-6
649031_ALDRICH
6912-63-6
7009-81-6
90-82-4
968-63-8
AC-20231
AC-20292
AC1L1JGK
AC1L1NUA
AC1L1RFA
AC1L1SR1
AC1L1T31
AC1L1Y3M
AC1O8JUO
AC1Q3XJE
AC1Q3XJM
AC1Q3XJN
AC1Q59F5
AC1Q7701
AI3-02761
AKOS000268842
AR-1A0126
AR-1I7143
Acunaso
Acunaso (TN)
Afrinol
Ambap299-42-3
BIDD:GT0817
BRN 3197916
BRN 4231286
BSPBio_001946
BSPBio_001968
BSPBio_003261
Benylin Decongestant
Besan
Biophedrin
C01575
C02765
C10H15NO
CHEBI:15407
CHEBI:51209
CHEMBL1590
CHEMBL211456
CHEMBL357080
CID11972440
CID5032
CID62946
CID6710657
CID7028
CID8650
CID9294
CID9457
CPD-9954
CPDD 0049
Cenafed
D00124
D08449
DB00852
DB01364
Decofed
DivK1c_000181
DivK1c_000451
DivK1c_000461
Drixoral N.D.
EINECS 202-017-0
EINECS 202-018-6
EINECS 206-080-5
EINECS 206-292-8
EINECS 206-293-3
Eciphin
Efedrin
Efidac/24
Eltor 120
Ephedral
Ephedremal
Ephedrin
Ephedrine
Ephedrine (TN)
Ephedrine (USP)
Ephedrine [USAN:BAN]
Ephedrine l-form
Ephedrital
Ephedrol
Ephedrosan
Ephedrotal
Ephedsol
Ephendronal
Ephoxamin
Fedrin
Genaphed
HSDB 3072
HSDB 3177
I-Sedrin
I01-3584
I01-8925
I01-8928
 
IDI1_000181
IDI1_000451
IDI1_000461
Isoephedrine
Jsp005664
KBio1_000181
KBio1_000451
KBio1_000461
KBio2_001358
KBio2_001500
KBio2_003926
KBio2_004068
KBio2_006494
KBio2_006636
KBio3_001188
KBio3_001446
KBio3_002762
KBioGR_001013
KBioGR_001763
KBioSS_001358
KBioSS_001500
KST-1A9168
Kratedyn
L(+)-psi-Ephedrine
L(-)-Ephedrine
L-(+)-Ephedrine
L-(-)-Ephedrine
L-Ephedrine
L-erythro-2-(Methylamino)-1-phenylpropan-1-ol
L000968
LS-125921
LS-125922
LS-43083
LS-63961
LS-63962
LS-63963
LS-63964
Lexofedrin
Lopac-E-3250
Lopac0_000501
MLS000069657
Manadrin
Mandrin
Maxenal
MolPort-001-684-474
MolPort-001-684-477
MolPort-001-684-478
MolPort-001-684-479
MolPort-001-769-085
Myfedrine
NCGC00015408-01
NCGC00015408-02
NCGC00162174-01
NCGC00178180-01
NCGC00178889-01
NCI-C55652
NCI60_002955
NINDS_000181
NINDS_000451
NINDS_000461
NSC 165609
NSC 170951
NSC 8971
NSC165609
NSC170951
NSC8971
Nasol
Neodurasina
Neodurasina (TN)
Oprea1_287330
PDSP1_000168
PDSP1_001106
PDSP1_001343
PDSP1_001345
PDSP1_001346
PDSP1_001347
PDSP2_000167
PDSP2_001090
PDSP2_001327
PDSP2_001329
PDSP2_001330
PDSP2_001331
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoephedrine (D)
Pseudoephedrinum
Psi-ephedrin
Psi-ephedrine
Robidrine
SMR000059174
SPBio_000214
SPBio_001365
SPBio_001377
ST023802
STK367993
STOCK1N-42675
Sanedrine
Spectrum2_000137
Spectrum2_001303
Spectrum2_001309
Spectrum3_000414
Spectrum3_000563
Spectrum3_001771
Spectrum4_000497
Spectrum4_001162
Spectrum5_000650
Spectrum5_000879
Spectrum5_001106
Spectrum_000878
Spectrum_001020
Sudafed
Sudafed Decongestant
UNII-03VRY66076
UNII-7CUC9DDI9F
UNII-GN83C131XS
Vencipon
WLN: QYR & Y1 & M1
WLN: QYR&Y1&M1
Zephrol
d-Ephedrine
d-Isoephedrine
d-Pseudoephedrine
d-psi-Ephedrine
l-Ephedrine
l-Pseudoephedrine
racephedrine
trans-Ephedrine
15
PseudoephedrineapprovedPhase 343890-82-47028
Synonyms:
( )-Pseudoephedrine
(+)-(1S,2S)-Pseudoephedrine
(+)-Pseudoephedrine
(+)-Psi-ephedrine
(+)-psi-Ephedrine
(+)-threo-Ephedrine
(1S,2S)-(+)-Pseudoephedrine
(1S,2S)-2-(methylamino)-1-phenylpropan-1-ol
(1S,2S)-2-Methylamino-1-phenyl-1-propanol
(1S,2S)-Pseudoephedrine
(1S,2S)-Pseudoephedrine, polymer-bound
1-Ephedrine
2-(Methylamino)-1-phenyl-1-propanol
287636_ALDRICH
304-87-0
30987-59-8
37577-31-4
649031_ALDRICH
90-82-4
AC-20292
AC1L1NUA
Acunaso
Acunaso (TN)
Afrinol
BIDD:GT0817
BRD-K84175871-003-02-2
BSPBio_003261
Balminil Decongestant Syrup
Benylin Decongestant
Benzenemethanol, alpha-((1S)-1-(methylamino)ethyl)-, (alpha-S)- (9CI)
Besan
C02765
C10H15NO
CHEBI:51209
CHEMBL1590
CID7028
CPD-9954
Cenafed
D-Isoephedrine
D-Pseudoephedrine
D-Pseudoephedrine base
D-Psi-2-Methylamino-1-phenyl-1-propanol
D-Psi-2-methylamino-1-phenyl-1-propanol
D-Psi-Ephedrine
D-Psi-ephedrine
D08449
DB00852
Decofed
Dimetapp Decongestant
Dimetapp Decongestant Pediatric Drops
DivK1c_000451
Drixoral N.D.
Drixoral Nasal Decongestant
EINECS 202-018-6
Efidac 24 Pseudoephedrine Hcl
Efidac/24
Eltor 120
Ephed 60
Ephedrine
Genaphed
HSDB 3177
I01-8928
IDI1_000451
Isoephedrine
KBio1_000451
 
KBio2_001358
KBio2_003926
KBio2_006494
KBio3_002762
KBioGR_001763
KBioSS_001358
L(+)-Psi-Ephedrine
L(+)-Psi-ephedrine
L(+)-psi-Ephedrine
L-(+)-Pseudoephedrine
LS-125922
Lopac-E-3250
Maxenal
MolPort-001-684-474
Myfedrine
NCGC00015408-01
NCGC00178180-01
NCI60_002955
NINDS_000451
Neodurasina
Neodurasina (TN)
Novafed
PDSP1_001347
PSEUDOEPHEDRINE
Pedia Care
Pseudo
Pseudo 60's
Pseudo-12
Pseudoefedrina
Pseudoefedrina [INN-Spanish]
Pseudoephedrine
Pseudoephedrine (D)
Pseudoephedrine (INN)
Pseudoephedrine D-form
Pseudoephedrine Ephedrine
Pseudoephedrine Hydrochloride
Pseudoephedrine [INN:BAN]
Pseudoephedrine d-form
Pseudoephedrine hydrochloride
Pseudoephedrine sulfate
Pseudoephedrinum
Pseudoephedrinum [INN-Latin]
Psi-ephedrin
Psi-ephedrine
Robidrine
SPBio_001365
STOCK1N-42675
Spectrum2_001303
Spectrum3_001771
Spectrum4_001162
Spectrum5_000650
Spectrum_000878
Sudafed
Sudafed Decongestant
Sudafed Decongestant 12 Hour
Sudafed Decongestant Extra Strength
Suphedrine
Triaminic AM Decongestant Formula
Triaminic Infant Oral Decongestant Drops
UNII-7CUC9DDI9F
alpha-(1-(Methylamino)ethyl)benzyl alcohol
d-Isoephedrine
d-Pseudoephedrine
d-psi-2-Methylamino-1-phenyl-1-propanol
d-psi-Ephedrine
trans-Ephedrine
16AntipruriticsPhase 3586
17Nasal DecongestantsPhase 3406
18AcidophilusNutraceuticalPhase 2, Phase 3444

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1Topical Cyclosporine for Vernal Keratoconjunctivitis (VKC) in RwandaCompletedNCT01211327Phase 4
2Study of the Clinical and Biological Efficacity of NAAXIA SINE® in Vernal KeratoconjunctivitisCompletedNCT00357019Phase 4
3Topical Tacrolimus in Vernal KeratoconjunctivitisRecruitingNCT02456025Phase 4
4Cyclosporin A Eye Drop Treatment in Vernal KeratoconjunctivitisCompletedNCT00426023Phase 3
5Lactobacillus Rhamnosus GG Oral Treatment Efficacy on Vernal Keratoconjunctivitis TreatmentCompletedNCT00445120Phase 2, Phase 3
6Phase III Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal KeratoconjunctivitisCompletedNCT00567762Phase 3
7Phase III, Long-Term, Open-Label, Extension Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal KeratoconjunctivitisCompletedNCT00567918Phase 3
8Efficacy and Tolerance of Nova22007 Versus Vehicle in Patients With Vernal Keratoconjunctivitis (VKC)CompletedNCT00328653Phase 2, Phase 3
9Efficacy Study of FK-506 and Cyclosporine in Vernal Keratoconjunctivits (VKC)CompletedNCT01068054Phase 2, Phase 3
10Double-Masked Trial of NOVA22007 (1mg/mL Ciclosporin/Cyclosporine) Versus Vehicle in Pediatric Patients With Active Severe Vernal KeratoconjunctivitisActive, not recruitingNCT01751126Phase 3
11Cytokine Assay in Tears of Healthy Children and With Vernal Keratoconjunctivitis: Case Control Study and Monitoring of Cases at 6 MonthsRecruitingNCT02057822

Search NIH Clinical Center for Vernal Keratoconjunctivitis

Genetic Tests for Vernal Keratoconjunctivitis

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Anatomical Context for Vernal Keratoconjunctivitis

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MalaCards organs/tissues related to Vernal Keratoconjunctivitis:

33
Eye, Testes, Neutrophil, T cells, Thyroid

Animal Models for Vernal Keratoconjunctivitis or affiliated genes

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MGI Mouse Phenotypes related to Vernal Keratoconjunctivitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.0ICAM1, IL13, IL4, IL5, MMP9
2MP:00053887.4CCL11, CXCR3, IL13, IL4, IL5, MMP9
3MP:00053976.4CCL11, CCL5, CXCR3, ICAM1, IL13, IL4
4MP:00053876.1CCL11, CCL5, CXCR3, ICAM1, IL13, IL4

Publications for Vernal Keratoconjunctivitis

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Articles related to Vernal Keratoconjunctivitis:

(show top 50)    (show all 292)
idTitleAuthorsYear
1
Microarray-based IgE detection in tears of patients with vernal keratoconjunctivitis. (26235361)
2015
2
Vernal Keratoconjunctivitis and immune-mediated diseases: One unique way to symptom control? (25692810)
2015
3
Intracellular IL-4, IL-5, and IFN-I^ as the main characteristic of CD4+CD30+ T cells after allergen stimulation in patients with vernal keratoconjunctivitis. (25999672)
2015
4
In vivo confocal microscopy of meibomian glands and palpebral conjunctiva in vernal keratoconjunctivitis. (26044472)
2015
5
Increased incidence of thyroid dysfunction and autoimmunity in patients with vernal keratoconjunctivitis. (25140177)
2014
6
CCL20/MIP-3 alpha mRNA expression in the conjunctival epithelium of normal individuals and patients with vernal keratoconjunctivitis. (25172034)
2014
7
Treatment of asymmetrical vernal keratoconjunctivitis with supratarsal corticosteroid injection. (25410033)
2014
8
Surgical resection and amniotic membrane transplantation for treatment of refractory giant papillae in vernal keratoconjunctivitis. (23086371)
2013
9
Management of vernal keratoconjunctivitis. (25135808)
2013
10
Use of cyclosporine A and tacrolimus in treatment of vernal keratoconjunctivitis. (23625179)
2013
11
Severe vernal keratoconjunctivitis successfully treated with subcutaneous omalizumab. (23607979)
2013
12
Vernal keratoconjunctivitis: an update. (23038763)
2013
13
Steroid-induced ocular hypertension in Asian children with severe vernal keratoconjunctivitis. (22927736)
2012
14
Fluid-filled scleral contact lenses in vernal keratoconjunctivitis. (22367220)
2012
15
Ocular surface disease: a case of vernal keratoconjunctivitis. (20971677)
2011
16
In vivo laser scanning confocal microscopy of vernal keratoconjunctivitis. (20662846)
2011
17
Vernal keratoconjunctivitis in school children in Rwanda and its association with socio-economic status: a population-based survey. (21976577)
2011
18
Treatment of severe vernal keratoconjunctivitis with 1% topical cyclosporine in an Italian cohort of 197 children. (19840298)
2010
19
Vernal keratoconjunctivitis: a major review. (18786127)
2009
20
Perilimbal conjunctival pigmentation in Chinese patients with vernal keratoconjunctivitis. (17464306)
2008
21
Vernal keratoconjunctivitis at Guinness Eye Centre, Luth (a five year study). (19062462)
2008
22
Natural killer cells in vernal keratoconjunctivitis. (17893656)
2007
23
Antibody array-generated cytokine profiles of tears of patients with vernal keratoconjunctivitis or giant papillary conjunctivitis. (16767372)
2006
24
Topical cyclosporine 0.5 per cent and preservative-free ketorolac tromethamine 0.5 per cent in vernal keratoconjunctivitis. (15061303)
2004
25
Tumor necrosis factor-alpha (TNF-alpha) in seasonal allergic conjunctivitis and vernal keratoconjunctivitis. (14552593)
2003
26
The T-lymphocyte chemoattractant Mig is highly expressed in vernal keratoconjunctivitis. (14597036)
2003
27
Videokeratography findings in children with vernal keratoconjunctivitis versus those of healthy children. (12414408)
2002
28
Active matrix metalloproteinases in the tear fluid of individuals with vernal keratoconjunctivitis. (12209100)
2002
29
Expression of T lymphocyte chemoattractants and activation markers in vernal keratoconjunctivitis. (12234902)
2002
30
Surgical treatment of limbal vernal keratoconjunctivitis by resection of a limbal lesion. (12543198)
2002
31
Langerhans' cells in vernal keratoconjunctivitis express the costimulatory molecule B7-2 (CD86), but not B7-1 (CD80). (11702979)
2001
32
Expression of chemokine receptors in vernal keratoconjunctivitis. (11673306)
2001
33
Cyclosporine effects on clinical findings and impression cytology specimens in severe vernal keratoconjunctivitis. (11399937)
2001
34
Nedocromil sodium eye drops are more effective than sodium cromoglycate eye drops for the long-term management of vernal keratoconjunctivitis. (10202368)
1999
35
Vernal keratoconjunctivitis in a Stockholm ophthalmic centre--epidemiological, functional, and immunologic investigations. (10551301)
1999
36
Pharmacological mechanism of topical lodoxamide treatment in vernal keratoconjunctivitis: a flow-cytometric study. (9483586)
1998
37
Effects of lodoxamide, disodium cromoglycate and fluorometholone on tear leukotriene levels in vernal keratoconjunctivitis. (9683957)
1998
38
Topical cyclosporin A 2% in the treatment of vernal keratoconjunctivitis. (9246280)
1997
39
Lodoxamide in vernal keratoconjunctivitis. (8740338)
1996
40
IgE, IgE receptors, and other immunocytochemical markers in atopic and nonatopic patients with vernal keratoconjunctivitis. (7777271)
1995
41
Increased plasma levels of nerve growth factor in vernal keratoconjunctivitis and relationship to conjunctival mast cells. (7657550)
1995
42
Increased serum levels of eosinophil cationic protein and eosinophil-derived neurotoxin (protein X) in vernal keratoconjunctivitis. (7800361)
1994
43
Lodoxamide for vernal keratoconjunctivitis. (8121328)
1994
44
Efficacy of lodoxamide 0.1% ophthalmic solution in resolving corneal epitheliopathy associated with vernal keratoconjunctivitis. (8154531)
1994
45
Treatment of vernal keratoconjunctivitis a double-masked study. (22822779)
1993
46
Efficacy and safety of lodoxamide 0.1% vs cromolyn sodium 4% in patients with vernal keratoconjunctivitis. (1598953)
1992
47
Frequency of chlamydia in patients with vernal keratoconjunctivitis. (2488657)
1989
48
Limbal vernal keratoconjunctivitis with a hypertrophic limbal mass lesion. (3566030)
1987
49
A comparison between 2% and 4% sodium cromoglycate eye drops in the treatment of vernal keratoconjunctivitis. (6821197)
1982-1983
50
Vernal keratoconjunctivitis in an Israeli group of patients and its treatment with sodium cromoglycate. (6800400)
1982

Variations for Vernal Keratoconjunctivitis

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Expression for genes affiliated with Vernal Keratoconjunctivitis

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Search GEO for disease gene expression data for Vernal Keratoconjunctivitis.

Pathways for genes affiliated with Vernal Keratoconjunctivitis

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Pathways related to Vernal Keratoconjunctivitis according to GeneCards Suite gene sharing:

(show all 22)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6IL4, IL5
29.6CCL11, CXCR3
39.3CCL11, IL4, IL5
49.2IL13, IL4, IL5
5
Show member pathways
9.2IL13, IL4, IL5
69.2IL13, IL4, IL5
7
Show member pathways
9.2IL13, IL4, IL5
89.2IL13, IL4, IL5
99.1CCL5, MMP9
109.1CCL5, MMP9
119.1CCL5, MMP9
12
Show member pathways
9.1CCL11, CCL5, CXCR3
13
Show member pathways
9.0CCL11, CCL5, ICAM1
148.6ICAM1, IL4, MMP9
158.6ICAM1, IL13, IL4, IL5
16
Show member pathways
8.5CCL5, ICAM1, IL13, IL4
178.5CCL5, ICAM1, MMP9
18
Show member pathways
7.9CCL11, ICAM1, IL13, IL4, IL5, RNASE3
19
Show member pathways
7.8CCL11, CCL5, CXCR3, IL13, IL4, IL5
20
Show member pathways
7.8CCL11, CCL5, CXCR3, IL13, IL4, IL5
21
Show member pathways
7.8CCL11, CCL5, CXCR3, IL13, IL4, IL5
22
Show member pathways
7.6CCL11, CCL5, CXCR3, ICAM1, MMP9

GO Terms for genes affiliated with Vernal Keratoconjunctivitis

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Cellular components related to Vernal Keratoconjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.0CXCR3, ICAM1, IL13, IL4
2extracellular regionGO:00055766.9CCL11, CCL5, IL13, IL4, IL5, MMP9
3extracellular spaceGO:00056156.6CCL11, CCL5, ICAM1, IL13, IL4, IL5

Biological processes related to Vernal Keratoconjunctivitis according to GeneCards Suite gene sharing:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of complement-dependent cytotoxicityGO:190366010.4IL13, IL4
2regulation of proton transportGO:001015510.4IL13, IL4
3microglial cell activationGO:000177410.3IL13, IL4
4positive regulation of immunoglobulin productionGO:000263910.2IL13, IL4
5chronic inflammatory responseGO:000254410.2CCL11, CCL5
6positive regulation of mast cell degranulationGO:004330610.2IL13, IL4
7eosinophil chemotaxisGO:004824510.2CCL11, CCL5
8monocyte chemotaxisGO:000254810.2CCL11, CCL5
9negative regulation of neuron deathGO:190121510.1CCL5, IL13
10positive regulation of release of sequestered calcium ion into cytosolGO:005128110.1CXCR3, IL13
11lymphocyte chemotaxisGO:004824710.1CCL11, CCL5
12positive regulation of actin filament polymerizationGO:003083810.0CCL11, ICAM1
13positive regulation of JAK-STAT cascadeGO:004642710.0CCL5, IL5
14innate immune response in mucosaGO:00022279.9IL4, RNASE3
15leukocyte cell-cell adhesionGO:00071599.9CCL5, ICAM1
16cellular response to cytokine stimulusGO:00713459.8CCL5, IL13
17positive regulation of B cell proliferationGO:00308909.8IL13, IL4, IL5
18negative regulation of endothelial cell apoptotic processGO:20003529.7ICAM1, IL13, IL4
19response to organic cyclic compoundGO:00140709.4CCL5, ICAM1, IL4
20positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.4ICAM1, IL4, IL5
21response to lipopolysaccharideGO:00324969.3CCL5, ICAM1, IL13
22chemokine-mediated signaling pathwayGO:00700989.3CCL11, CCL5, CXCR3
23cellular response to interleukin-1GO:00713479.3CCL11, CCL5, ICAM1
24cellular response to tumor necrosis factorGO:00713569.3CCL11, CCL5, ICAM1
25positive regulation of angiogenesisGO:00457669.1CCL11, CCL5, CXCR3
26response to ethanolGO:00454719.1ICAM1, IL13, IL4
27chemotaxisGO:00069358.8CCL11, CCL5, CXCR3, IL4
28positive regulation of ERK1 and ERK2 cascadeGO:00703748.7CCL11, CCL5, ICAM1
29inflammatory responseGO:00069548.5CCL11, CCL5, CXCR3, IL13, IL5
30immune responseGO:00069558.4CCL11, CCL5, IL13, IL4, IL5

Molecular functions related to Vernal Keratoconjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine receptor bindingGO:000512610.1IL13, IL4
2cytokine activityGO:00051259.2IL13, IL4, IL5

Sources for Vernal Keratoconjunctivitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet