MCID: VRT001
MIFTS: 31

Vertebral Artery Occlusion

Categories: Cardiovascular diseases

Aliases & Classifications for Vertebral Artery Occlusion

MalaCards integrated aliases for Vertebral Artery Occlusion:

Name: Vertebral Artery Occlusion 12 14 69
Occlusion and Stenosis of Vertebral Artery 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11299
ICD10 32 I65.0
ICD9CM 34 433.2

Summaries for Vertebral Artery Occlusion

MalaCards based summary : Vertebral Artery Occlusion, also known as occlusion and stenosis of vertebral artery, is related to basilar artery occlusion and cervicitis. An important gene associated with Vertebral Artery Occlusion is AARS (Alanyl-TRNA Synthetase), and among its related pathways/superpathways are GDNF-Family Ligands and Receptor Interactions and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Affiliated tissues include brain and bone, and related phenotypes are growth/size/body region and integument

Related Diseases for Vertebral Artery Occlusion

Diseases related to Vertebral Artery Occlusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 basilar artery occlusion 29.4 FOSB PLG SLC25A16
2 cervicitis 10.4
3 conjugate gaze palsy 10.4 F3 PLG
4 cerebral falx meningioma 10.3 F3 PLG
5 intestinal impaction 10.3 F3 PLG
6 leech infestation 10.3 F3 PLG
7 giant hemangioma 10.3 F3 PLG
8 blue toe syndrome 10.3 F3 PLG
9 intracranial embolism 10.3 F3 PLG
10 nodular ganglioneuroblastoma 10.3 BDNF NTRK2
11 femoral neuropathy 10.3 F3 PLG
12 aneurysm 10.3
13 dysbaric osteonecrosis 10.3 F3 PLG
14 anterior cranial fossa meningioma 10.3 F3 PLG
15 hemometra 10.2 F3 SLC25A16
16 undetermined early-onset epileptic encephalopathy 10.2 AARS NTRK2
17 lemierre's syndrome 10.2 F3 PLG SLC25A16
18 korean hemorrhagic fever 10.2 F3 PLG
19 cerebral arterial disease 10.1 MRAS SLC25A16
20 carotid artery thrombosis 10.1 CSF2 F3
21 vertebrobasilar insufficiency 10.0
22 hepatic vascular disease 10.0 F3 PLG SST
23 vein disease 10.0 F3 PLG SST
24 status epilepticus 10.0 BDNF NTRK2 SST
25 intermediate coronary syndrome 9.9 F3 PLG
26 rheumatoid arthritis 9.9
27 arthritis 9.9
28 ischemia 9.9
29 lateral medullary syndrome 9.9
30 brain stem infarction 9.9
31 osteochondroma 9.9
32 headache 9.9
33 nervous system disease 9.8 BDNF CSF2 NOS2 RBFOX3
34 nevus, epidermal 9.7
35 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 9.7
36 nasopharyngeal carcinoma 9.7
37 glass syndrome 9.7
38 hydrocephalus 9.7
39 hemidystonia 9.7
40 thrombosis 9.7
41 nasopharyngitis 9.7
42 acute cervicitis 9.7
43 intracranial aneurysm 9.7
44 vestibular neuronitis 9.7
45 locked-in syndrome 9.7
46 spondylosis 9.7
47 central nervous system origin vertigo 9.7
48 cerebritis 9.7
49 neuronitis 9.7
50 carotid artery dissection 9.7

Graphical network of the top 20 diseases related to Vertebral Artery Occlusion:



Diseases related to Vertebral Artery Occlusion

Symptoms & Phenotypes for Vertebral Artery Occlusion

MGI Mouse Phenotypes related to Vertebral Artery Occlusion:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.96 NTRK2 PLG AARS SOCS2 SST BDNF
2 integument MP:0010771 9.7 PLG AARS SOCS2 BDNF CSF2 F3
3 nervous system MP:0003631 9.61 NTRK2 PLG AARS SST BDNF CSF2
4 respiratory system MP:0005388 9.17 NTRK2 PLG SOCS2 BDNF CSF2 F3

Drugs & Therapeutics for Vertebral Artery Occlusion

Search Clinical Trials , NIH Clinical Center for Vertebral Artery Occlusion

Genetic Tests for Vertebral Artery Occlusion

Anatomical Context for Vertebral Artery Occlusion

MalaCards organs/tissues related to Vertebral Artery Occlusion:

38
Brain, Bone

Publications for Vertebral Artery Occlusion

Articles related to Vertebral Artery Occlusion:

(show top 50) (show all 141)
# Title Authors Year
1
Cryptic Recanalization of Chronic Vertebral Artery Occlusion by Head Rotation. ( 28117210 )
2017
2
Combined Use of Intraoperative Indocyanine Green and Dynamic Angiography in Rotational Vertebral Artery Occlusion. ( 29114306 )
2017
3
Evaluation of a Traumatic Vertebral Artery Occlusion. ( 28254602 )
2017
4
Rapid Progression of Vertebral Artery Occlusion After Radiotherapy for Nasopharyngeal Carcinoma. ( 29250760 )
2017
5
Therapeutic internal carotid or vertebral artery occlusion using the WEB device. ( 26861025 )
2016
6
Congenital Spinal Malformation and Stroke: Aneurysmal Dilatations and Bilateral Rotational Vertebral Artery Occlusion. ( 26679068 )
2016
7
Bilateral vertebral artery occlusion without headache in giant cell arteritis. ( 27508209 )
2016
8
Duplex Ultrasonography-Detected Positional Vertebral Artery Occlusion in Upper Cervical Rheumatoid Arthritis. ( 26583470 )
2016
9
Bilateral sub-axial rotational vertebral artery occlusion in a setting of a prior cervical construct. ( 27609452 )
2016
10
Delayed bilateral vertebral artery occlusion after cervical spine injury: a case report. ( 28053772 )
2016
11
Vertebral artery occlusion and recanalization after cervical facet dislocation. ( 27535628 )
2016
12
Combined use of intraoperative indocyanine green and dynamic angiography in rotational vertebral artery occlusion. ( 27041076 )
2016
13
Temporary vertebral artery occlusion after C3 fracture dislocation injury and spontaneous resolution following reduction and instrumented fusion: case report and literature review. ( 27798854 )
2016
14
A Novel Canine Model of Acute Vertebral Artery Occlusion. ( 26545253 )
2015
15
Wake-up stroke in a young woman with rotational vertebral artery occlusion due to far-lateral cervical disc herniation. ( 25932602 )
2015
16
Bilateral Medial Medullary Infarction with Nondominant Vertebral Artery Occlusion. ( 26175270 )
2015
17
Ruptured Anterior Spinal Artery Aneurysm Associated with Bilateral Vertebral Artery Occlusion Treated by Surgical Clipping. ( 26079782 )
2015
18
Corrective spinal surgery may be protective against stroke in patients with blunt traumatic vertebral artery occlusion. ( 26186525 )
2015
19
Rotational vertebral artery occlusion syndrome: Misnomers and classification. ( 25660966 )
2015
20
Rotational vertebral artery occlusion secondary to adjacent-level degeneration following anterior cervical discectomy and fusion. ( 24745352 )
2014
21
Preoperative visualization of the marginal tentorial artery as an unusual collateral pathway in a patient with symptomatic bilateral vertebral artery occlusion undergoing arterial bypass surgery: A 7.0-T magnetic resonance imaging study. ( 25422785 )
2014
22
Distal embolic brain infarction due to recanalization of asymptomatic vertebral artery occlusion resulting from cervical spine injury: a case report. ( 25435840 )
2014
23
Delayed Brain Infarction due to Bilateral Vertebral Artery Occlusion Which Occurred 5 Days after Cervical Trauma. ( 25328652 )
2014
24
Atypical Anterior Spinal Artery Infarction due to Left Vertebral Artery Occlusion Presenting with Bilateral Hand Weakness. ( 24829605 )
2014
25
Evaluation of Rotational Vertebral Artery Occlusion Using Ultrasound Facilitates the Detection of Arterial Dissection in the Atlas Loop. ( 25307799 )
2014
26
Upbeat nystagmus during head rotation in rotational vertebral artery occlusion. ( 24691903 )
2014
27
Fusion Surgery for Recurrent Cerebellar Infarctions due to Bilateral Atlanto-axial Rotational Vertebral Artery Occlusion. ( 24732857 )
2014
28
Fusion surgery for recurrent cerebellar infarctions due to bilateral atlantoaxial rotational vertebral artery occlusion. ( 24918470 )
2014
29
Spontaneous atraumatic vertebral artery occlusion due to physiological cervical extension: case report. ( 24438424 )
2014
30
Rotational vertebral artery occlusion: mechanisms and long-term outcome. ( 23696552 )
2013
31
Endovascular angioplasty for extracranial vertebral artery occlusion without visualization of the stump of the artery ostium. ( 23803622 )
2013
32
Bilateral mechanical rotational vertebral artery occlusion. ( 23465174 )
2013
33
Endovascular reconstruction of vertebral artery occlusion prior to basilar thrombectomy in a series of six patients presenting with acute symptomatic basilar thrombosis. ( 23737492 )
2013
34
Osteochondroma of C1 causing vertebral artery occlusion. ( 22844969 )
2013
35
A Ruptured Aneurysm Arising at the Leptomeningeal Collateral Circulation from the Extracranial Vertebral Artery to the Posterior Inferior Cerebellar Artery Associated with Bilateral Vertebral Artery Occlusion. ( 24321776 )
2013
36
Coronary subclavian steal from a left internal thoracic artery coronary bypass graft due to ipsilateral subclavian artery stenosis and an arteriovenous graft in a hemodialysis patient with left vertebral artery occlusion. ( 23728554 )
2013
37
Impact of contralateral carotid or vertebral artery occlusion in patients undergoing carotid endarterectomy or carotid artery stenting. ( 24360588 )
2013
38
Traumatic, high-cervical, coronal-plane spondyloptosis with unilateral vertebral artery occlusion: treatment using a prophylactic arterial bypass graft, open reduction, and instrumented segmental fusion. ( 24286529 )
2013
39
Rotational vertebral artery occlusion associated with occipitoatlantal assimilation, atlantoaxial subluxation, and basilar impression. ( 23287744 )
2013
40
Death due to extensive cervicomedullary infarction following iatrogenic vertebral artery occlusion. ( 22350824 )
2012
41
Fatal outcome after brain stem infarction related to bilateral vertebral artery occlusion - case report of a detrimental complication of cervical spine trauma. ( 21756312 )
2011
42
Vertebral artery occlusion with Amplatzer vascular plug 4 to prevent subsequent endoleak in stent-graft treatment of subclavian artery gunshot injury. ( 21724841 )
2011
43
Traumatic Carotid Artery Dissection and Bilateral Vertebral Artery Occlusion after a Horse Attack: An Unusual Combination and Etiology. ( 21830193 )
2011
44
Dominant vertebral artery occlusion during ipsilateral head tilt. ( 21555738 )
2011
45
A rare complication of a unilateral vertebral artery occlusion, which resulted in a basilar emboli after a C5-C6 bifacet dislocation in a professional rugby player: case study. ( 21377596 )
2011
46
Impact of carotid disease on posterior circulation in patients with vertebral artery occlusion--a functional transcranial Doppler study. ( 22141282 )
2011
47
Stenting of a symptomatic long-segment extracranial vertebral artery occlusion. ( 21990790 )
2011
48
Clinical outcome of patients with acute posterior circulation stroke and bilateral vertebral artery occlusion. ( 22518265 )
2011
49
Rotational vertebral artery occlusion in a child with multiple strokes: a case-based update. ( 20959996 )
2010
50
Artery-to-artery embolism with a mobile mural thrombus due to rotational vertebral artery occlusion. ( 19021833 )
2010

Variations for Vertebral Artery Occlusion

Expression for Vertebral Artery Occlusion

Search GEO for disease gene expression data for Vertebral Artery Occlusion.

Pathways for Vertebral Artery Occlusion

Pathways related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.55 BDNF MRAS NTRK2
2 11.34 BDNF NTRK2 SST
3 9.77 BDNF NTRK2

GO Terms for Vertebral Artery Occlusion

Biological processes related to Vertebral Artery Occlusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron apoptotic process GO:0043524 9.13 AARS BDNF NTRK2
2 brain-derived neurotrophic factor receptor signaling pathway GO:0031547 8.62 BDNF NTRK2

Sources for Vertebral Artery Occlusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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