Aliases & Classifications for Vestibular Nystagmus

MalaCards integrated aliases for Vestibular Nystagmus:

Name: Vestibular Nystagmus 12 14
Nystagmus Associated with Disorder of the Vestibular System 12 69

Classifications:



External Ids:

Disease Ontology 12 DOID:14070
ICD9CM 35 379.54
SNOMED-CT 64 46888001
UMLS 69 C0155379

Summaries for Vestibular Nystagmus

MalaCards based summary : Vestibular Nystagmus, also known as nystagmus associated with disorder of the vestibular system, is related to regular astigmatism and neuronitis, and has symptoms including deficiencies of smooth pursuit movements An important gene associated with Vestibular Nystagmus is TIMELESS (Timeless Circadian Clock). The drugs Histamine and Meclizine have been mentioned in the context of this disorder. Affiliated tissues include testes and eye, and related phenotypes are growth/size/body region and mortality/aging

Related Diseases for Vestibular Nystagmus

Diseases related to Vestibular Nystagmus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
id Related Disease Score Top Affiliating Genes
1 regular astigmatism 10.3 FUT2 MED12
2 neuronitis 10.3
3 orbital granuloma 10.2 MED12 TWIST1
4 natural killer cell leukemia 10.2 MED12 TWIST1
5 vestibular neuronitis 10.0
6 cerebritis 9.9
7 ametropic amblyopia 9.8 CYCS DPT
8 foodborne botulism 9.8 DPT FUT2
9 congenital nystagmus 9.7
10 cervicitis 9.7
11 strabismus 9.7
12 epicondylitis 5.2 CETP CYCS DEGS1 DPT DTNA FOXD3

Comorbidity relations with Vestibular Nystagmus via Phenotypic Disease Network (PDN):


Labyrinthitis

Graphical network of the top 20 diseases related to Vestibular Nystagmus:



Diseases related to Vestibular Nystagmus

Symptoms & Phenotypes for Vestibular Nystagmus

UMLS symptoms related to Vestibular Nystagmus:


deficiencies of smooth pursuit movements

MGI Mouse Phenotypes related to Vestibular Nystagmus:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.91 FOXD3 GBA MED12 NF2 TWIST1 CYCS
2 mortality/aging MP:0010768 9.85 CYCS DEGS1 DTNA FOXD3 GBA MED12
3 craniofacial MP:0005382 9.72 CYCS FOXD3 MED12 NF2 TWIST1
4 nervous system MP:0003631 9.56 CYCS DTNA FOXD3 GBA MED12 MYRF
5 skeleton MP:0005390 9.23 CYCS DEGS1 DTNA FOXD3 GBA MED12

Drugs & Therapeutics for Vestibular Nystagmus

Drugs for Vestibular Nystagmus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
2
Meclizine Approved Phase 4 569-65-3 4034
3 Anti-Bacterial Agents Phase 4
4 Anti-Infective Agents Phase 4
5 Gentamicins Phase 4
6 Adjuvants, Anesthesia Phase 4
7 Anesthetics Phase 4
8 Anti-Allergic Agents Phase 4
9 Antiemetics Phase 4
10 Autonomic Agents Phase 4
11 Bromides Phase 4
12 Butylscopolammonium Bromide Phase 4
13 Cholinergic Agents Phase 4
14 Cholinergic Antagonists Phase 4
15 Gastrointestinal Agents Phase 4
16 Histamine Antagonists Phase 4
17 Histamine H1 Antagonists Phase 4
18
Histamine Phosphate Phase 4 51-74-1 65513
19 Muscarinic Antagonists Phase 4
20 Mydriatics Phase 4
21 Neurotransmitter Agents Phase 4
22 Parasympatholytics Phase 4
23 Peripheral Nervous System Agents Phase 4
24 Scopolamine hydrobromide Phase 4 114-49-8
25
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
26 Anti-Inflammatory Agents Phase 2
27 Antineoplastic Agents, Hormonal Phase 2
28 glucocorticoids Phase 2
29 Hormone Antagonists Phase 2
30 Hormones Phase 2
31 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2

Interventional clinical trials:

(show all 17)

id Name Status NCT ID Phase Drugs
1 Motion Sickness Medications and Vestibular Time Constant Recruiting NCT03270839 Phase 4 Bonine 25Mg Chewable Tablet;Kwells;Placebo Oral Tablet
2 Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function Recruiting NCT02415257 Phase 4 Gentamicin
3 Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function Recruiting NCT02379754 Phase 4 Gentamicins
4 Prednisone Treatment for Vestibular Neuronitis Completed NCT00271791 Phase 2 Prednisone;Prednisone
5 Effect of Vestibular Rehabilitation - a Randomized Controlled Trial Completed NCT00702832
6 Vertigo Perception and Quality of Life in Patients After Surgical Treatment of Vestibular Schwannoma Completed NCT02963896 gentamicin
7 Vestibular Evoked Myogenic Potentials in Benign Paroxysmal Positional Vertigo (VEMP in BPPV) Completed NCT01004913
8 Telemedical Examination of a Three-Component Oculomotor Testing Battery Completed NCT02938221
9 Clinical Aspects of Patients With Benign Paroxysmal Positional Vertigo (BPPV) and Migraine Completed NCT02615314
10 Study of the Effectiveness of Vestibular Stimulation Treatment in the Depressive Phase of Bipolar Disorder Recruiting NCT02778256
11 Gaze Holding in Cerebellar Patients Recruiting NCT02185313
12 Functional Link Between Hippocampal and Vestibular Systems: a Pilot Study in Epilepsy Surgery Active, not recruiting NCT01285921
13 Helpfulness of the Vibration Test Performed in Room Light on Clients With Inner Ear Problems Enrolling by invitation NCT02626052
14 Simultaneous Recordings of Cervical and Ocular Vestibular-evoked Myogenic Potentials Enrolling by invitation NCT03049683
15 Reactivity of the Vestibular System to Caloric Vestibular Stimulation in Schizophrenia Not yet recruiting NCT03048370
16 Boosting Reward-based Attention Through VEstibular STimulation Not yet recruiting NCT03213119
17 Prospective Assessment of Peripheral-vestibular Function After Skull Base Surgery Not yet recruiting NCT02773277

Search NIH Clinical Center for Vestibular Nystagmus

Genetic Tests for Vestibular Nystagmus

Anatomical Context for Vestibular Nystagmus

MalaCards organs/tissues related to Vestibular Nystagmus:

39
Testes, Eye

Publications for Vestibular Nystagmus

Articles related to Vestibular Nystagmus:

(show top 50) (show all 153)
id Title Authors Year
1
Mental Tasking and Caloric-Induced Vestibular Nystagmus Utilizing Videonystagmography. ( 27657668 )
2016
2
Comparison of techniques for identification of peripheral vestibular nystagmus. ( 23098070 )
2012
3
Optimal estimator models for spatial orientation and vestibular nystagmus. ( 21416377 )
2011
4
The effect of mental alerting on peripheral vestibular nystagmus during spontaneous, gaze (30 degrees left, 30 degrees right) and body positional (left & right lateral lying) testing using electronystagmography (ENG). ( 18923981 )
2008
5
Latent nystagmus: vestibular nystagmus with a twist. ( 14769597 )
2004
6
Behavioural characteristics of the quick phase of vestibular nystagmus before and after unilateral labyrinthectomy in guinea pig. ( 12632231 )
2003
7
On the distribution of fast-phase intervals in optokinetic and vestibular nystagmus. ( 12111270 )
2002
8
Otolith effect on torsional quick phases of vestibular nystagmus in humans. ( 11960870 )
2002
9
Generation of the quick phase of horizontal vestibular nystagmus. ( 11914784 )
2002
10
Both actual and imagined locomotion suppress spontaneous vestibular nystagmus. ( 12438939 )
2002
11
Three-dimensional binocular kinematics of torsional vestibular nystagmus during convergence on head-fixed targets in humans. ( 11431493 )
2001
12
Shift of the beating field of vestibular nystagmus: an orientation strategy? ( 9779928 )
1998
13
Visual suppression of vestibular nystagmus. ( 9581190 )
1998
14
Effect of unilateral section of cervical afferent nerve upon optokinetic response and vestibular nystagmus induced by sinusoidal rotation in guinea pigs. ( 9870641 )
1998
15
Elicitation of vestibular nystagmus by a step mode of horizontal linear acceleration. ( 12212621 )
1998
16
Suppression of vestibular nystagmus by forced convergence in normal human subjects. ( 9027681 )
1997
17
Asymmetry of motion VEP in infantile strabismus and in central vestibular nystagmus. ( 7493538 )
1995
18
Maturation of the fast component of vestibular nystagmus during childhood and young adulthood. ( 8073857 )
1994
19
Three-dimensional characteristics of rhesus monkey vestibular nystagmus after velocity steps. ( 7921349 )
1994
20
Transient analysis of vestibular nystagmus. ( 8274538 )
1993
21
The influence of gravity on vestibular nystagmus in humans. ( 11538541 )
1993
22
Shortening of vestibular nystagmus in response to velocity steps by microinjection of carbachol in the rabbit's cerebellar flocculus. ( 8454004 )
1993
23
The neurotransmitter of inhibitory synaptic inputs on inhibitory burst neurons (IBNs) controlling vestibular nystagmus in the cat. ( 8095121 )
1993
24
Visual suppression of torsional vestibular nystagmus in rhesus monkeys. ( 1509697 )
1992
25
Effects of serotonin, GABA and glycine on the activity of pause neurons during vestibular nystagmus in the cat. ( 1662457 )
1991
26
The caloric vestibular nystagmus during short lasting microgravity. ( 11537150 )
1991
27
Monocular and binocular visual suppression of vestibular nystagmus. ( 1927433 )
1991
28
Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo? ( 2257903 )
1990
29
Influence of gravitoinertial force on vestibular nystagmus in man observed in a centrifuge. ( 11537334 )
1989
30
Effect of betahistine dihydrochloride compared with cinnarizine on induced vestibular nystagmus. ( 2612026 )
1989
31
Effects of afloqualone on vestibular nystagmus and the lateral vestibular nucleus. ( 2570880 )
1989
32
Transfer of optokinetic activity to vestibular nystagmus. ( 3260439 )
1988
33
Vestibular and non-vestibular nystagmus in examination of dizzy patients. ( 3265257 )
1988
34
The role of the vestibular system in eye-head coordination and the generation of vestibular nystagmus. ( 3265010 )
1988
35
Effect of betahistine dihydrochloride on induced vestibular nystagmus: a double blind study. ( 3581491 )
1987
36
The effects of alerting tasks on caloric induced vestibular nystagmus. ( 3556813 )
1987
37
Fast component threshold for vestibular nystagmus in the rabbit. ( 3612590 )
1987
38
Influence of voluntary ocular deviation on vestibular nystagmus. ( 3491488 )
1986
39
The relationship of optokinetic nystagmus to pursuit eye movements, vestibular nystagmus and to saccades in humans. A clinical study. ( 3487909 )
1986
40
Computer simulation of fixation suppression of vestibular nystagmus in normal persons. ( 6534191 )
1984
41
On the predictive control of foveal eye tracking and slow phases of optokinetic and vestibular nystagmus. ( 6707954 )
1984
42
Vertical optokinetic nystagmus and vestibular nystagmus in the monkey: up-down asymmetry and effects of gravity. ( 6608454 )
1984
43
Non-linear effects in visual suppression of vestibular nystagmus. ( 6605258 )
1983
44
Neuronal organization of the premotor system controlling horizontal conjugate eye movements and vestibular nystagmus. ( 6660109 )
1983
45
Different time constants for optokinetic and vestibular nystagmus with a single velocity-storage element. ( 6605178 )
1983
46
The effects of strobe rate of head-fixed visual targets on suppression of vestibular nystagmus. ( 6605870 )
1983
47
Interference between synchronous optokinetic nystagmus and vestibular nystagmus. ( 7102295 )
1982
48
Asymmetries of vertical vestibular nystagmus in the cat. ( 7215503 )
1981
49
Cat medial pontine neurons in vestibular nystagmus. ( 6951436 )
1981
50
Cat medial pontine reticular neurons related to vestibular nystagmus: firing pattern, location and projection. ( 6975150 )
1981

Variations for Vestibular Nystagmus

Expression for Vestibular Nystagmus

Search GEO for disease gene expression data for Vestibular Nystagmus.

Pathways for Vestibular Nystagmus

GO Terms for Vestibular Nystagmus

Biological processes related to Vestibular Nystagmus according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ceramide biosynthetic process GO:0046513 8.96 DEGS1 GBA
2 oligodendrocyte development GO:0014003 8.62 MED12 MYRF

Sources for Vestibular Nystagmus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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