MCID: VST003
MIFTS: 31

Vestibular Nystagmus malady

Category: Eye diseases

Aliases & Classifications for Vestibular Nystagmus

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Aliases & Descriptions for Vestibular Nystagmus:

Name: Vestibular Nystagmus 11 13
 
Nystagmus Associated with Disorder of the Vestibular System 11 66

Classifications:



External Ids:

Disease Ontology11 DOID:14070
SNOMED-CT60 46888001
ICD9CM30 379.54

Summaries for Vestibular Nystagmus

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MalaCards based summary: Vestibular Nystagmus, also known as nystagmus associated with disorder of the vestibular system, is related to neuronitis and blind hypertensive eye, and has symptoms including ataxia, cerebellar ataxia and ophthalmoplegia. An important gene associated with Vestibular Nystagmus is DTNA (Dystrobrevin Alpha). Affiliated tissues include eye and testes, and related mouse phenotypes are craniofacial and skeleton.

Related Diseases for Vestibular Nystagmus

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Diseases related to Vestibular Nystagmus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1neuronitis10.4
2blind hypertensive eye10.3FUT2, MED12
3natural killer cell leukemia10.3MED12, TWIST1
4vestibular neuronitis10.1
5cerebritis10.0
6cervicitis9.8
7strabismus9.8
8congenital nystagmus9.8
9ametropic amblyopia9.8CYCS, DPT
10foodborne botulism9.8DPT, FUT2
11toxic labyrinthitis5.1CACNA1A, CETP, CYCS, DEGS1, DPT, DTNA

Comorbidity relations with Vestibular Nystagmus via Phenotypic Disease Network (PDN):


Labyrinthitis

Graphical network of diseases related to Vestibular Nystagmus:



Diseases related to vestibular nystagmus

Symptoms for Vestibular Nystagmus

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UMLS symptoms related to Vestibular Nystagmus:


ataxia, cerebellar ataxia, ophthalmoplegia, vertigo, smooth pursuit movement deficiency, difficulty standing, abnormal coordination, equilibration disorder, inner ear signs and symptoms

Drugs & Therapeutics for Vestibular Nystagmus

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Drugs for Vestibular Nystagmus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
PrednisonePhase 2131853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
 
Juvason
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
2glucocorticoidsPhase 24756

Interventional clinical trials:

(show all 18)
idNameStatusNCT IDPhase
1Gentamicin Treatment Prior to Schwannoma Surgery - No Residual FunctionRecruitingNCT02415257Phase 4
2Gentamicin Treatment Prior to Schwannoma Surgery - Residual FunctionRecruitingNCT02379754Phase 4
3Treatment of Geotropic Horizontal Canal Benign Paroxysmal Positional VertigoCompletedNCT01366430Phase 3
4Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional VertigoCompletedNCT00810641Phase 3
5Prednisone Treatment for Vestibular NeuronitisCompletedNCT00271791Phase 2
6Treatment of Apogeotropic Horizontal Canal Benign Paroxysmal Positional VertigoCompletedNCT02046980Phase 2
7Effect of Vestibular Rehabilitation - a Randomized Controlled TrialCompletedNCT00702832
8Vestibular Evoked Myogenic Potentials in Benign Paroxysmal Positional Vertigo (VEMP in BPPV)CompletedNCT01004913
9Clinical Aspects of Patients With Benign Paroxysmal Positional Vertigo (BPPV) and MigraineCompletedNCT02615314
10Accuracy of a Diagnostic Algorithm for the Differential Diagnosis of Vertigo in the ED: the STANDING.CompletedNCT02782962
11Study of the Effectiveness of Vestibular Stimulation Treatment in the Depressive Phase of Bipolar DisorderRecruitingNCT02778256
12Gaze Holding in Cerebellar PatientsRecruitingNCT02185313
13BPPV Treatment in Biaxial Rotational ChairRecruitingNCT01905800
14Treatment of Posterior Canal Type of Benign Paroxysmal Positional VertigoRecruitingNCT01822002
15BPPV With CRP: Single Versus Multiple CyclesRecruitingNCT02701218
16Functional Link Between Hippocampal and Vestibular Systems: a Pilot Study in Epilepsy SurgeryActive, not recruitingNCT01285921
17Helpfulness of the Vibration Test Performed in Room Light on Clients With Inner Ear ProblemsEnrolling by invitationNCT02626052
18Prospective Assessment of Peripheral-vestibular Function After Skull Base SurgeryNot yet recruitingNCT02773277

Search NIH Clinical Center for Vestibular Nystagmus

Genetic Tests for Vestibular Nystagmus

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Anatomical Context for Vestibular Nystagmus

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MalaCards organs/tissues related to Vestibular Nystagmus:

34
Eye, Testes

Animal Models for Vestibular Nystagmus or affiliated genes

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MGI Mouse Phenotypes related to Vestibular Nystagmus:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.3CYCS, FOXD3, MED12, NF2, TWIST1
2MP:00053907.7CYCS, DEGS1, DTNA, FOXD3, GBA, MED12
3MP:00036317.5CACNA1A, CYCS, DTNA, FOXD3, GBA, MED12
4MP:00053867.1CACNA1A, CYCS, DEGS1, DTNA, GBA, MYRF
5MP:00053786.8CACNA1A, CYCS, DEGS1, DPT, DTNA, FOXD3
6MP:00107686.5CACNA1A, CYCS, DEGS1, DTNA, FOXD3, GBA

Publications for Vestibular Nystagmus

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Articles related to Vestibular Nystagmus:

(show top 50)    (show all 153)
idTitleAuthorsYear
1
The effect of mental alerting on peripheral vestibular nystagmus during spontaneous, gaze (30 degrees left, 30 degrees right) and body positional (left & right lateral lying) testing using electronystagmography (ENG). (18923981)
2008
2
Latent nystagmus: vestibular nystagmus with a twist. (14769597)
2004
3
Generation of the quick phase of horizontal vestibular nystagmus. (11914784)
2002
4
Three-dimensional binocular kinematics of torsional vestibular nystagmus during convergence on head-fixed targets in humans. (11431493)
2001
5
Effect of unilateral section of cervical afferent nerve upon optokinetic response and vestibular nystagmus induced by sinusoidal rotation in guinea pigs. (9870641)
1998
6
Elicitation of vestibular nystagmus by a step mode of horizontal linear acceleration. (12212621)
1998
7
Suppression of vestibular nystagmus by forced convergence in normal human subjects. (9027681)
1997
8
Three-dimensional characteristics of rhesus monkey vestibular nystagmus after velocity steps. (7921349)
1994
9
The neurotransmitter of inhibitory synaptic inputs on inhibitory burst neurons (IBNs) controlling vestibular nystagmus in the cat. (8095121)
1993
10
Shortening of vestibular nystagmus in response to velocity steps by microinjection of carbachol in the rabbit's cerebellar flocculus. (8454004)
1993
11
Transient analysis of vestibular nystagmus. (8274538)
1993
12
Visual suppression of torsional vestibular nystagmus in rhesus monkeys. (1509697)
1992
13
The caloric vestibular nystagmus during short lasting microgravity. (11537150)
1991
14
Effects of afloqualone on vestibular nystagmus and the lateral vestibular nucleus. (2570880)
1989
15
Transfer of optokinetic activity to vestibular nystagmus. (3260439)
1988
16
The role of the vestibular system in eye-head coordination and the generation of vestibular nystagmus. (3265010)
1988
17
The effects of alerting tasks on caloric induced vestibular nystagmus. (3556813)
1987
18
Effect of betahistine dihydrochloride on induced vestibular nystagmus: a double blind study. (3581491)
1987
19
Provoked vestibular nystagmus and caloric reactions after sudden loss of vestibular function. (6976679)
1981
20
Cat medial pontine reticular neurons related to vestibular nystagmus: firing pattern, location and projection. (6975150)
1981
21
Downbeat nystagmus: a type of central vestibular nystagmus. (6970904)
1981
22
Postsynaptic inhibition underlying spike suppression of secondary vestibular neurons during quick phases of vestibular nystagmus. (7052421)
1980
23
Modification of single neural elements in vestibular nystagmus by anesthesia. (7405571)
1980
24
Vestibular nystagmus under hyperbaric conditions. (317701)
1979
25
A model of Alexander's law of vestibular nystagmus. (314822)
1979
26
Presynaptic impulses in the abducens nucleus and their relation to postsynaptic potentials in motoneurons during vestibular nystagmus. (880991)
1977
27
Suppression of vestibular nystagmus. (889309)
1977
28
Horizontal vestibular nystagmus. II. Activity patterns of medial vestibular neurones during nystagmus. (1001388)
1976
29
Horizontal vestibular nystagmus. I. Identification of medial vestibular neurones. (1001387)
1976
30
On the predominance of anti-compensatory eye movements in vestibular nystagmus. (1086101)
1976
31
Effect of visual input on vestibular nystagmus in autistic children. (4547196)
1974
32
Organization of vestibular nystagmus in oblique oculomotor system. (4359789)
1974
33
Neuronal activity underlying vestibular nystagmus in the oblique oculomotor system of the cat. (4468059)
1974
34
Computer analysis of evoked vestibular nystagmus in healthy subjects. 2. Caloric stimulation--sequential analysis. (4616831)
1974
35
A contribution to the mechanism of vestibular nystagmus. The role of afferent impulses. (5068761)
1972
36
Vestibular nystagmus--a differential reaction. (5574305)
1971
37
Computer analysis of induced vestibular nystagmus rotatory stimulation of normal cats. (5316099)
1971
38
On vestibular nystagmus. Definition and identification of nystagmus and a model to explain the genesis of vestibular nystagmus. (5411701)
1970
39
Computer analysis of vestibular nystagmus in cats. (5514921)
1970
40
Influence of head position on the habituation of vertical vestibular nystagmus in the cat. (5785604)
1969
41
Relations between vestibular nystagmus and visual performance. (5301455)
1968
42
Adaptation to vestibular disorientation. X. Modification of vestibular nystagmus and "vertigo" by means of visual stimulation. AM 68-28. (5307250)
1968
43
Vestibular nystagmus in infants and the effect of streptomycin in the neonatal period. (5303312)
1968
44
Nystagmographic analysis of the rapid component of vestibular nystagmus caused by rotatory acceleration. (5215170)
1965
45
Effects of mental activity on vestibular nystagmus and the electroencephalogram. (13694770)
1961
46
Oculomotor function following cerebral hemidecortication in the monkey. A study with special reference to optokinetic and vestibular nystagmus. (14430699)
1960
47
The vestibulogram: a graphic record for the evaluation of vestibular nystagmus. (14422924)
1960
48
Further studies of the effects of mental set upon vestibular nystagmus. (13694771)
1960
49
Role of vestibular nystagmus in the visual perception of a moving target in the dark. (20985345)
1946
50
Vestibular Nystagmus. (19981314)
1920

Variations for Vestibular Nystagmus

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Expression for genes affiliated with Vestibular Nystagmus

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Search GEO for disease gene expression data for Vestibular Nystagmus.

Pathways for genes affiliated with Vestibular Nystagmus

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GO Terms for genes affiliated with Vestibular Nystagmus

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Biological processes related to Vestibular Nystagmus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1oligodendrocyte developmentGO:001400310.1MED12, MYRF
2neuromuscular synaptic transmissionGO:00072749.9CACNA1A, DTNA
3ceramide biosynthetic processGO:00465139.5DEGS1, GBA

Sources for Vestibular Nystagmus

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet