MCID: VRL007
MIFTS: 54

Viral Encephalitis malady

Categories: Neuronal diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Viral Encephalitis

Aliases & Descriptions for Viral Encephalitis:

Name: Viral Encephalitis 12 14 69
Encephalitis, Arbovirus 42
Arbovirus Encephalitis 69
Epidemic Encephalitis 12
Encephalitis Viral 52

Classifications:



External Ids:

Disease Ontology 12 DOID:646
MeSH 42 D004671
NCIt 47 C34576
UMLS 69 C0014055

Summaries for Viral Encephalitis

Disease Ontology : 12 An encephalitis that involves inflammation of the brain caused by viral infection.

MalaCards based summary : Viral Encephalitis, also known as encephalitis, arbovirus, is related to hepatitis and rift valley fever. An important gene associated with Viral Encephalitis is VCAM1 (Vascular Cell Adhesion Molecule 1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Ethanol and Formaldehyde have been mentioned in the context of this disorder. Affiliated tissues include brain, t cells and monocytes, and related phenotypes are hematopoietic system and cardiovascular system

Wikipedia : 71 Viral encephalitis is a type of encephalitis caused by a... more...

Related Diseases for Viral Encephalitis

Diseases in the Encephalitis family:

Viral Encephalitis Autoimmune Encephalitis

Diseases related to Viral Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 265)
id Related Disease Score Top Affiliating Genes
1 hepatitis 29.9 IL10 IL6 TNF
2 rift valley fever 29.5 IL1B IL6 TNF
3 conduct disorder 29.5 IL10 IL6 TNF
4 cerebral palsy 10.8
5 encephalitis 10.8
6 japanese encephalitis 10.6
7 tick-borne encephalitis 10.4
8 intussusception 10.3 IL1B TNF
9 pyridoxal 5'-phosphate-dependent epilepsy 10.2 IL10 TNF
10 tau syndrome 10.2 IL1B TNF
11 von economo's disease 10.2
12 oculomotor nerve paralysis 10.2 IL1B IL6
13 dyslexia 5 10.2 IL6 TNF
14 tubular renal disease-cardiomyopathy syndrome 10.2 IL10 TNF
15 common peroneal nerve lesion 10.2 IL1B IL6
16 aortic atherosclerosis 10.2 IL6 TNF
17 degenerative disc disease 10.2 IL6 TNF
18 stocco dos santos syndrome 10.2 IL1B TNF
19 muscular dystrophy-dystroglycanopathy , type a, 12 10.2 CCL2 IL1B
20 lagophthalmos 10.2 IL10 TNF
21 vogt-koyanagi-harada disease 10.2 CXCL10 IL6 TNF
22 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 10.2 IL1B TNF
23 encephalopathy, acute, infection-induced, 4 10.2
24 la crosse encephalitis 10.2
25 eastern equine encephalitis 10.2
26 western equine encephalitis 10.2
27 st. louis encephalitis 10.2
28 anal paget's disease 10.2 IL1B IL6 TNF
29 bipolar i disorder 10.2 IL1B IL6 TNF
30 human immunodeficiency virus infectious disease 10.2 IL1B IL6 TNF
31 interval angle-closure glaucoma 10.2 CCL2 IL1B
32 uterine corpus cancer 10.2 CXCL10 IL1B TNF
33 tinea capitis 10.2 IL1B IL6 TNF
34 pemphigus vulgaris, familial 10.2 IL6 TNF VCAM1
35 measles 10.2 IL1B IL6 TNF
36 dextrocardia 10.2 IL1B IL6 TNF
37 mikulicz disease 10.2 IL1B IL6 TNF
38 unilateral multicystic dysplastic kidney 10.2 IL6 TNF
39 acquired thrombocytopenia 10.2 IL1B IL6 TNF
40 benign neonatal seizures 10.2 IL1B IL6 TNF
41 migraine with aura 10.2 IL1B IL6 TNF
42 focal dystonia 10.2 CCL2 IL6 VCAM1
43 neuropathy 10.2 IL1B IL6 TNF
44 keratoconus 10.2 IL1B IL6 TNF
45 ureter inverted papilloma 10.2 IL10 IL6
46 splenic artery aneurysm 10.2 IL1B IL6 TNF
47 multiple vertebral anomalies unusual facies 10.2 IL10 TNF
48 pancreas lymphoma 10.1 IL1B IL6 TNF
49 cervix small cell carcinoma 10.1 IL6 TNF VCAM1
50 peripheral artery disease 10.1 IL10 TNF VCAM1

Graphical network of the top 20 diseases related to Viral Encephalitis:



Diseases related to Viral Encephalitis

Symptoms & Phenotypes for Viral Encephalitis

MGI Mouse Phenotypes related to Viral Encephalitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.07 VCAM1 IL6 TNF CCL5 MBP CXCL10
2 cardiovascular system MP:0005385 10.03 TNF VCAM1 IL6 CXCL10 PTGS1 IL10
3 cellular MP:0005384 10.01 TNF VCAM1 IL6 MBP CXCL10 PTGS1
4 immune system MP:0005387 10 VCAM1 TNF CCL2 CCL5 MBP CXCL10
5 homeostasis/metabolism MP:0005376 9.97 TNF VCAM1 IL6 MBP CXCL10 PTGS1
6 neoplasm MP:0002006 9.63 IL6 TNF PTGS1 IL10 PTGS2 IL1B
7 nervous system MP:0003631 9.56 TNF IL6 MBP CXCL10 PTGS1 IL10
8 reproductive system MP:0005389 9.17 TNF VCAM1 IL6 MBP PTGS1 IL10

Drugs & Therapeutics for Viral Encephalitis

Drugs for Viral Encephalitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 165)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 4 64-17-5 702
2
Formaldehyde Approved, Vet_approved Phase 4,Phase 3 50-00-0 712
3
Natalizumab Approved, Investigational Phase 4 189261-10-7
4
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
5
Dimenhydrinate Approved Phase 4 523-87-5 441281
6
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
7
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
8 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
9 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1
10 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
11 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
12 Antibodies Phase 4,Phase 3,Phase 2,Phase 1
13 Gastrointestinal Agents Phase 4,Phase 3,Phase 1
14 Heptavalent Pneumococcal Conjugate Vaccine Phase 4,Phase 3
15 Disinfectants Phase 4,Phase 3
16 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Phase 2
17 Hormone Antagonists Phase 4,Phase 3,Phase 2
18 Hormones Phase 4,Phase 3,Phase 2
19 Peripheral Nervous System Agents Phase 4,Phase 3
20 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
21 Vasoconstrictor Agents Phase 4
22 Epinephryl borate Phase 4
23 Antiemetics Phase 4,Phase 3
24 Racepinephrine Phase 4
25 Autonomic Agents Phase 4,Phase 3
26 glucocorticoids Phase 4,Phase 3
27 Anti-Inflammatory Agents Phase 4,Phase 3
28 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
29 Prednisolone acetate Phase 4
30 Neuroprotective Agents Phase 4
31 Prednisolone hemisuccinate Phase 4
32 Prednisolone phosphate Phase 4
33 Methylprednisolone acetate Phase 4
34 Methylprednisolone Hemisuccinate Phase 4
35
Famciclovir Approved Phase 3 104227-87-4 3324
36
Zanamivir Approved, Investigational Phase 3 139110-80-8 60855
37
Aluminum hydroxide Approved Phase 3,Phase 1 21645-51-2
38
rituximab Approved Phase 3 174722-31-7 10201696
39
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
40
chloroquine Approved, Vet_approved Phase 3 54-05-7 2719
41 DEET Phase 3
42 Insect Repellents Phase 3
43 Antimetabolites Phase 3,Phase 2,Phase 1
44 Antiviral Agents Phase 3,Phase 2,Phase 1
45 Acyclovir Phase 3
46 valacyclovir Phase 3
47
Lactitol Phase 3 585-86-4 3871
48 2-Aminopurine Phase 3
49 Antimalarials Phase 3,Phase 2,Phase 1
50 Antirheumatic Agents Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 203)
id Name Status NCT ID Phase
1 Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Unknown status NCT01954810 Phase 4
2 Cellular and Humoral Immunity in Elderly After Immunization With a Japanese Encephalitis Vaccine Unknown status NCT01398540 Phase 4
3 Kaiser Permanente HIV Cohort Study Completed NCT01339403 Phase 4
4 Cervicovaginal Immune Responses to 3 Deltoid or Thigh Intramuscular (IM) TicoVac Completed NCT01710189 Phase 4
5 Study to Investigate the Seropersistence of TBE Virus Antibodies Approx. 3 Years After a Booster Vaccination With FSME-IMMUN 0.25 mL JUNIOR in Children Completed NCT00163618 Phase 4
6 Immunogenicity of a Live Attenuated Chimeric JE Vaccine (IMOJEV) as a Booster Dose in Thai Children Primed With CD.JEVAX Completed NCT02526550 Phase 4
7 Post-licensure Safety Study of IMOJEV® in Thailand Completed NCT01981967 Phase 4
8 Influence of Persistent CMV-infection on Immune Senescence Completed NCT00461695 Phase 4
9 TBE Seropersistence up to 10 Years After First Booster in Adults Completed NCT01582698 Phase 4
10 TBE Antibody Persistence and Booster Vaccination Study in Adults (Follow-up to Study 223) Completed NCT00503529 Phase 4
11 Immunogenicity and Safety Study of a Third Vaccination With FSME-IMMUN 0.5 mL in Subjects Previously Vaccinated According to a Rapid Immunization Schedule (Follow-up to Study 225) Completed NCT00163540 Phase 4
12 Immunogenicity of Co-administration of Measles and Japanese Encephalitis Vaccines Completed NCT02643433 Phase 4
13 TBE Antibody Persistence and Booster Vaccination Study in Children and Adolescents (Follow-up to Study 209) Completed NCT00161967 Phase 4
14 A Prospective, Open Label Study of Human T Cell Responses to Live Attenuated Japanese Encephalitis Vaccine SA14-14-2 Completed NCT01656200 Phase 4
15 Long-term Immunogenicity and Safety of Fourth Administration of Boryung Cell-Culture Japanese Encephalitis Vaccineinj Completed NCT02532569 Phase 4
16 Study to Evaluate Long Term Immunogenicity up to 10 Years After the First Booster Immunization With Tick Borne Encephalitis Vaccine in Adults Who Received 1 of 3 Different Primary Vaccination Schedules Completed NCT01562444 Phase 4
17 6-year Antibody Check After Third Vaccination Against Japanese Encephalitis Completed NCT02039440 Phase 4
18 An Extension Study to Determine the Persistence of Tick-borne Encephalitis (TBE)-Specific Antibody Responses Among Children and Adolescents Previously Immunized Against TBE Completed NCT01106482 Phase 4
19 Long-term Immunogenicity After Receipt of JE Vaccine and Antibody Response and Safety to a Booster Dose Completed NCT02514746 Phase 4
20 This is a Study to Assess the Safety and Immunogenicity of Ixiaro® (IC51) in an Elderly Population Completed NCT01158599 Phase 4
21 Immunogenicity and Safety Study of a Rapid Immunization Schedule With FSME-IMMUN 0.5 mL in Healthy Adults Aged 16 - 65 Years Completed NCT00161954 Phase 4
22 Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination Completed NCT00804219 Phase 4
23 Evaluation of Long-Term Immunogenicity in Subjects Boosted With a TBE Vaccine for Adults Completed NCT00311493 Phase 4
24 Study of the Safety, Tolerability and Immune Response of TBE Vaccines Administered to Healthy Children Completed NCT00311441 Phase 4
25 Lot-to-lot Consistency Trial of JE Live Attenuated SA 14-14-2 Vaccine Completed NCT01567865 Phase 4
26 Evaluation of Long-Term Immunogenicity in Children and Adolescents Boosted With a New Pediatric TBE Vaccine After Five Years Completed NCT00452621 Phase 4
27 Investigation of the Seropersistence of TBE Antibodies and the Booster Response to FSME-IMMUN 0.5 ml in Adults Aged 18 - 67 Years Completed NCT00161785 Phase 4
28 Immunogenicity and Safety of Live Attenuated Varicella Vaccine Combined With Live Attenuated JE Vaccine Completed NCT01815073 Phase 4
29 Immediate Versus Deferred Antiretroviral Therapy in HIV-infected Patients Presenting With Acute AIDS-defining Events Completed NCT01417949 Phase 4
30 Study of Evaluating Safety and Immunogenicity of 23-Valent Pneumococcal Polysaccharide Vaccine With Influenza Vaccine in Children and Adults Completed NCT02062281 Phase 4
31 Postmarketing Surveillance Study for IMOJEV® in Republic of Korea Recruiting NCT02933710 Phase 4
32 Immunogenicity and Safety of Japanese Encephalitis Vaccine When Given With Measles-Mumps-Rubella Vaccine Recruiting NCT02880865 Phase 4
33 TBE Vaccination in Allergic Patients Recruiting NCT02511535 Phase 4
34 SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies Recruiting NCT02951559 Phase 4
35 Tick-Borne Encephalitis (TBE) Seropersistence After First Booster in Children, Adolescents and Young Adults (Follow-Up to Study 700401) Active, not recruiting NCT00894686 Phase 4
36 Safety and Effectiveness of Switching Relapsing MS Patients Treated With Natalizumab at Risk for PML to Teriflunomide Active, not recruiting NCT01970410 Phase 4
37 Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS) Terminated NCT01211665 Phase 4
38 Clinical Evaluation of Insect Repellent and Insecticide Treated Nets in Lao PDR Unknown status NCT00938379 Phase 3
39 Immunogenicity and Safety of Inactivated Vero Cell Derived Japanese Encephalitis Vaccine in Thai Children Completed NCT01408537 Phase 3
40 Live Attenuated Japanese Encephalitis (JE) Vaccine Coadministered With Measles Vaccine in Infants 9 Months of Age Completed NCT00463684 Phase 3
41 Boosterability of Live Attenuated Japanese Encephalitis (JE) Vaccine in Children Who Have Previously Received Inactivated JE Vaccine Completed NCT00463476 Phase 3
42 Determining Long-Term Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles Vaccine Completed NCT00412516 Phase 3
43 Determining Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles Vaccine Completed NCT00249769 Phase 3
44 Study of a Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV™) Compared to CD.JEVAX™ in Toddlers Completed NCT01396512 Phase 3
45 Study of Japanese Encephalitis Chimeric Virus Vaccine Given With Measles-Mumps-Rubella Vaccine in Taiwanese Toddlers Completed NCT01188343 Phase 3
46 A Study of Japanese Encephalitis Chimeric Virus Vaccine Compared With SA14-14-2 Vaccine in Infants and Toddlers Completed NCT01092507 Phase 3
47 Study of Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Previously Immunized With JE-CV Completed NCT01190228 Phase 3
48 Long-term Follow-up of Immunogenicity of a Single Dose of Japanese Encephalitis Chimeric Virus Vaccine in Toddlers Completed NCT01001988 Phase 3
49 Study of a Single Primary Dose Live Attenuated Japanese Encephalitis Chimeric Virus Vaccine (IMOJEV®) in Healthy Subjects Completed NCT02492165 Phase 3
50 Study of a Booster Dose of IMOJEV® Vaccine One Year After Primary Immunization in Healthy Children in South Korea Completed NCT01900444 Phase 3

Search NIH Clinical Center for Viral Encephalitis

Cochrane evidence based reviews: encephalitis, arbovirus

Genetic Tests for Viral Encephalitis

Anatomical Context for Viral Encephalitis

MalaCards organs/tissues related to Viral Encephalitis:

39
Brain, T Cells, Monocytes, Thalamus, Liver, Cortex, Cerebellum

Publications for Viral Encephalitis

Articles related to Viral Encephalitis:

(show top 50) (show all 313)
id Title Authors Year
1
Seasonality of Viral Encephalitis and Associated Environmental Risk Factors in Son La and Thai Binh Provinces in Vietnam from 2004 to 2013. ( 27799646 )
2017
2
Microglia retard dengue virus-induced acute viral encephalitis. ( 27279150 )
2016
3
Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis. ( 27307572 )
2016
4
Perspectives in Diagnosis and Treatment of Rabies Viral Encephalitis: Insights from Pathogenesis. ( 27324391 )
2016
5
Neuroprotection mediated by inhibition of calpain during acute viral encephalitis. ( 27345730 )
2016
6
Fulminant bilateral acute retinal necrosis syndrome associated with viral encephalitis: A case report. ( 27698716 )
2016
7
A clinico-radiological study on viral encephalitis patients- A hospital based study. ( 27727853 )
2016
8
Post-malaria neurological syndrome or viral encephalitis? ( 26744539 )
2016
9
Antiepileptic drugs for the primary and secondary prevention of seizures in viral encephalitis. ( 27209627 )
2016
10
The evaluation of a tailored intervention to improve the management of suspected viral encephalitis: protocol for a cluster randomised controlled trial. ( 25623603 )
2015
11
Viral encephalitis complicated by acute retinal necrosis syndrome: A case report. ( 26622338 )
2015
12
Probable toxic cause for suspected lychee-linked viral encephalitis. ( 25897979 )
2015
13
Early microlesion of viral encephalitis confirmed by galectin-3 expression after a virus inoculation. ( 25736950 )
2015
14
Herpes Simplex Viral Encephalitis Masquerading as a Classic Left MCA Stroke. ( 26770849 )
2015
15
Clinical characteristics and outcome of clinically diagnosed viral encephalitis in southwest China. ( 26205533 )
2015
16
The development of an intervention to promote adherence to national guidelines for suspected viral encephalitis. ( 25889994 )
2015
17
Differential Diagnosis of Restricted Diffusion of the Thalamus-Focus on Viral Encephalitis. ( 26425255 )
2015
18
Epidemiological features of viral encephalitis in Cangzhou of China with use of multiplex RT-PCR for five RNA viruses. ( 26118966 )
2015
19
Influence of malnutrition on adverse outcome in children with confirmed or probable viral encephalitis: a prospective observational study. ( 25695076 )
2015
20
Viral encephalitis in travellers. ( 25650207 )
2015
21
Viral encephalitis and its management through advanced molecular diagnostic methods: a review. ( 23737611 )
2014
22
Case of the season: dural arteriovenous fistula mimicking a bithalamic neoplasm or viral encephalitis. ( 24342671 )
2014
23
Antiepileptic drugs for the primary and secondary prevention of seizures in viral encephalitis. ( 25300175 )
2014
24
Immune system's role in viral encephalitis. ( 25189678 )
2014
25
Clinical approach to the syndromes of viral encephalitis, myelitis, and meningitis. ( 25015482 )
2014
26
Acute psychosis followed by fever--malignant neuroleptic syndrome or viral encephalitis? ( 25039118 )
2014
27
Gliomatosis cerebri mimicking acute viral encephalitis and with malignant transformation of partial lesions: A case report. ( 25120625 )
2014
28
Defining the chemokine basis for leukocyte recruitment during viral encephalitis. ( 24899190 )
2014
29
Clinical presentation of severe viral encephalitis with known causative agents in children: a retrospective study on 16 patients hospitalized in a pediatric intensive care unit (2008-2011). ( 24464514 )
2014
30
Acute viral encephalitis co-existing with fulminant hepatitis caused by Epstein-Barr virus. ( 25041777 )
2014
31
Secondary viral encephalitis in a patient with pyogenic liver abscess. ( 24967776 )
2014
32
Indoleamine 2,3-dioxygenase 1 is upregulated in activated microglia in mice cerebellum during acute viral encephalitis. ( 24530381 )
2014
33
Gliomatosis cerebri mimicking viral encephalitis in a 4-year-old child. ( 24717581 )
2014
34
Deep sequencing to identify the causes of viral encephalitis. ( 24699691 )
2014
35
Acute viral encephalitis. ( 23622326 )
2013
36
A case of Hashimoto's encephalopathy misdiagnosed as viral encephalitis. ( 24046804 )
2013
37
Subacute sclerosing panencephalitis and chronic viral encephalitis. ( 23622327 )
2013
38
Recombination in human coxsackievirus B5 strains that caused an outbreak of viral encephalitis in Henan, China. ( 23624679 )
2013
39
Generalized periodic epileptiform discharges in a case of viral encephalitis with a good prognosis. ( 23294491 )
2013
40
Mosquito-Host Interactions during and after an Outbreak of Equine Viral Encephalitis in Eastern Panama. ( 24339965 )
2013
41
IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis. ( 23992866 )
2013
42
Prospects for cannabinoid therapies in viral encephalitis. ( 24021420 )
2013
43
Underreporting of viral encephalitis and viral meningitis, Ireland, 2005-2008. ( 23965781 )
2013
44
Human cord blood-derived mononuclear cell transplantation for viral encephalitis-associated cognitive impairment: a case report. ( 23835552 )
2013
45
Dyschromatosis symmetrica hereditaria by ADAR1 mutations and viral encephalitis: a hidden link? ( 24261734 )
2013
46
Neuroimaging of six neurosyphilis cases mimicking viral encephalitis. ( 24007871 )
2013
47
Viral encephalitis in the ICU. ( 23830656 )
2013
48
Viral encephalitis. ( 24141509 )
2013
49
Management of suspected viral encephalitis in adults--Association of British Neurologists and British Infection Association National Guidelines. ( 22120595 )
2012
50
Novel inhibitors of neurotropic alphavirus replication that improve host survival in a mouse model of acute viral encephalitis. ( 22428985 )
2012

Variations for Viral Encephalitis

Expression for Viral Encephalitis

Search GEO for disease gene expression data for Viral Encephalitis.

Pathways for Viral Encephalitis

Pathways related to Viral Encephalitis according to GeneCards Suite gene sharing:

(show top 50) (show all 59)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.97 CCL2 CCL5 CXCL10 IL10 IL1B IL6
2
Show member pathways
13.78 CCL2 CCL5 CXCL10 IL10 IL1B IL6
3
Show member pathways
13.61 CCL2 CCL5 CXCL10 IL10 IL1B IL6
4
Show member pathways
13.39 CCL2 CCL5 CXCL10 IL10 IL1B IL6
5
Show member pathways
13.29 CCL2 CCL5 CXCL10 IL10 IL1B IL6
6
Show member pathways
13.26 CCL2 CCL5 CXCL10 IL10 IL1B IL6
7
Show member pathways
12.98 CCL2 CCL5 IL1B IL6 PTGS2 TNF
8
Show member pathways
12.93 CCL2 CCL5 CXCL10 IL10 IL1B IL6
9
Show member pathways
12.82 CCL2 CCL5 CXCL10 IL1B IL6 MX1
10
Show member pathways
12.73 CCL5 CXCL10 IL1B IL6 TNF
11
Show member pathways
12.59 CCL2 IL10 IL1B IL6 TNF
12
Show member pathways
12.55 IL10 IL1B IL6 TNF
13
Show member pathways
12.42 IL10 IL1B IL6 TNF
14
Show member pathways
12.4 CCL2 PTGS1 PTGS2 VCAM1
15
Show member pathways
12.36 CCL2 CXCL10 IL1B IL6 PTGS2 TNF
16
Show member pathways
12.31 CCL2 CCL5 IL1B IL6 PTGS1 PTGS2
17 12.3 CCL2 CCL5 CXCL10 IL10 IL1B PTGS1
18
Show member pathways
12.28 IL1B IL6 PTGS2 TNF
19
Show member pathways
12.27 IL10 IL1B PTGS2 TNF
20 12.24 IL10 IL1B IL6 TNF
21
Show member pathways
12.21 IL10 IL1B IL6 MX1 TNF
22
Show member pathways
12.2 CXCL10 IL1B IL6 TNF
23 12.19 IL10 IL1B IL6 TNF
24 12.11 CCL2 IL1B TNF VCAM1
25
Show member pathways
11.99 CCL2 CCL5 CXCL10
26
Show member pathways
11.98 IL10 IL1B IL6 TNF
27 11.96 IL10 IL6 TNF
28 11.96 CCL2 IL1B IL6 TNF VCAM1
29 11.94 CCL2 CXCL10 IL1B IL6 MBP PTGS2
30 11.92 IL10 IL1B IL6 TNF
31 11.91 IL1B PTGS2 TNF VCAM1
32 11.91 CCL2 CCL5 IL1B IL6 TNF
33 11.87 IL1B IL6 TNF
34 11.86 CCL2 IL10 IL1B IL6 PTGS2 TNF
35 11.81 IL10 IL1B IL6 TNF
36 11.8 IL10 IL1B IL6 TNF
37 11.79 IL10 IL1B TNF
38 11.76 IL10 IL6 TNF VCAM1
39 11.72 CCL2 CCL5 IL1B IL6 TNF
40
Show member pathways
11.71 IL1B IL6 PTGS2 TNF VCAM1
41 11.62 IL1B IL6 TNF
42 11.59 CCL2 CCL5 CXCL10 IL1B IL6 PTGS2
43 11.56 CCL2 IL1B TNF
44 11.54 CCL2 IL10 IL1B IL6 TNF VCAM1
45 11.52 IL1B IL6 TNF
46 11.44 IL10 IL1B IL6 TNF
47 11.4 IL10 IL1B IL6 TNF VCAM1
48 11.39 CCL5 IL1B IL6
49 11.35 IL1B IL6 TNF
50 11.35 IL10 IL1B IL6 TNF

GO Terms for Viral Encephalitis

Cellular components related to Viral Encephalitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 CCL2 CCL5 CXCL10 IL10 IL1B IL6
2 external side of plasma membrane GO:0009897 9.26 CXCL10 IL6 TNF VCAM1
3 extracellular space GO:0005615 9.23 CCL2 CCL5 CXCL10 IL10 IL1B IL6

Biological processes related to Viral Encephalitis according to GeneCards Suite gene sharing:

(show top 50) (show all 78)
id Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.97 CCL2 CCL5 IL1B MBP TNF
2 regulation of cell proliferation GO:0042127 9.96 CXCL10 IL6 PTGS1 PTGS2 TNF
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.95 CCL2 CCL5 IL6 TNF
4 cytokine-mediated signaling pathway GO:0019221 9.93 CCL2 IL1B IL6
5 defense response GO:0006952 9.92 CXCL10 MX1 TNF
6 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.92 IL1B IL6 TNF
7 cellular response to tumor necrosis factor GO:0071356 9.91 CCL2 CCL5 IL6 VCAM1
8 response to virus GO:0009615 9.9 CCL5 CXCL10 MX1 TNF
9 response to organic substance GO:0010033 9.89 IL10 PTGS2 TNF
10 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.89 IL10 IL1B IL6 TNF
11 aging GO:0007568 9.89 CCL2 IL10 IL6 PTGS2 VCAM1
12 cellular response to interleukin-1 GO:0071347 9.87 CCL2 CCL5 IL6
13 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.87 IL6 PTGS2 TNF
14 chemokine-mediated signaling pathway GO:0070098 9.86 CCL2 CCL5 CXCL10
15 regulation of insulin secretion GO:0050796 9.86 CCL5 IL1B TNF
16 neutrophil chemotaxis GO:0030593 9.85 CCL2 CCL5 IL1B
17 response to cytokine GO:0034097 9.85 CCL5 IL6 PTGS2
18 cellular response to organic cyclic compound GO:0071407 9.85 CCL2 CCL5 IL1B TNF
19 humoral immune response GO:0006959 9.84 CCL2 IL6 TNF
20 cell chemotaxis GO:0060326 9.84 CCL2 CCL5 CXCL10 VCAM1
21 positive regulation of cell adhesion GO:0045785 9.83 CCL2 CCL5 TNF
22 cellular response to lipopolysaccharide GO:0071222 9.83 CCL2 CXCL10 IL10 IL6 TNF
23 positive regulation of interleukin-6 production GO:0032755 9.82 IL1B IL6 TNF
24 negative regulation of viral genome replication GO:0045071 9.82 CCL5 MX1 TNF
25 monocyte chemotaxis GO:0002548 9.81 CCL2 CCL5 IL6
26 positive regulation of T cell proliferation GO:0042102 9.81 CCL5 IL1B IL6 VCAM1
27 cellular response to estradiol stimulus GO:0071392 9.79 CCL2 IL10 IL6
28 response to tumor necrosis factor GO:0034612 9.79 CCL2 CCL5 PTGS2
29 positive regulation of smooth muscle cell proliferation GO:0048661 9.78 CCL5 IL6 PTGS2 TNF
30 positive regulation of NF-kappaB import into nucleus GO:0042346 9.76 IL1B PTGS2 TNF
31 positive regulation of nitric oxide biosynthetic process GO:0045429 9.76 IL1B IL6 PTGS2 TNF
32 immune response GO:0006955 9.76 CCL2 CCL5 CXCL10 IL10 IL1B IL6
33 prostaglandin metabolic process GO:0006693 9.75 PTGS1 PTGS2
34 negative regulation of myoblast differentiation GO:0045662 9.75 CXCL10 TNF
35 response to vitamin D GO:0033280 9.75 CXCL10 PTGS2
36 positive regulation of interleukin-6 secretion GO:2000778 9.75 IL1B MBP
37 defense response to protozoan GO:0042832 9.75 IL10 IL6
38 positive regulation of JAK-STAT cascade GO:0046427 9.74 CCL5 IL6
39 negative regulation of lipid catabolic process GO:0050995 9.74 IL1B TNF
40 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.74 IL10 TNF
41 positive regulation of chemokine production GO:0032722 9.74 IL6 TNF
42 negative regulation of growth of symbiont in host GO:0044130 9.74 IL10 TNF
43 positive regulation of monocyte chemotaxis GO:0090026 9.74 CCL2 CCL5 CXCL10
44 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.73 IL1B TNF
45 positive regulation of macrophage chemotaxis GO:0010759 9.73 CCL2 CCL5
46 prostaglandin biosynthetic process GO:0001516 9.73 PTGS1 PTGS2
47 cellular response to hepatocyte growth factor stimulus GO:0035729 9.73 IL10 IL6
48 leukocyte tethering or rolling GO:0050901 9.73 TNF VCAM1
49 acute inflammatory response GO:0002526 9.73 IL6 VCAM1
50 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.72 IL1B TNF

Molecular functions related to Viral Encephalitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CCL2 CCL5 CXCL10
2 cytokine activity GO:0005125 9.17 CCL2 CCL5 CXCL10 IL10 IL1B IL6
3 prostaglandin-endoperoxide synthase activity GO:0004666 8.96 PTGS1 PTGS2

Sources for Viral Encephalitis

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10 dbSNP
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16 ExPASy
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