MCID: VRL017
MIFTS: 27

Viral Hemorrhagic Fever malady

Infectious category

Summaries for Viral Hemorrhagic Fever

Sources:
3CDC, 64Wikipedia, 33MalaCards
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CDC:3 VHFs are caused by viruses of five distinct families: Arenaviridae, Bunyaviridae, Filoviridae, Flaviviridae, and Paramyxoviridae. Each of these families share a number of features:

MalaCards: Viral Hemorrhagic Fever, also known as hemorrhagic fevers, viral, is related to hemorrhagic fever and ebola hemorrhagic fever, and has symptoms including fever/chilling, asthenia/fatigue/weakness and conjunctival injection/chemosis/red eye. An important gene associated with Viral Hemorrhagic Fever is LBR (lamin B receptor). Affiliated tissues include kidney, liver and t cells.

Wikipedia:64 The viral hemorrhagic (or haemorrhagic) fevers (VHFs) are a diverse group of animal and human illnesses... more...

Aliases & Classifications for Viral Hemorrhagic Fever

Sources:
43NIH Rare Diseases, 49Orphanet, 61UMLS, 58SNOMED-CT via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Characteristics (Orphanet epidemiological data):

49
viral hemorrhagic fever:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

viral hemorrhagic fever 43 49
hemorrhagic fevers, viral 61


External Ids:

SNOMED-CT via Orphanet58 240523007

Related Diseases for Viral Hemorrhagic Fever

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Viral Hemorrhagic Fever via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 15)
idRelated DiseaseScoreTop Affiliating Genes
1hemorrhagic fever11.0
2ebola hemorrhagic fever10.6
3marburg hemorrhagic fever10.4
4lassa fever10.4
5hantavirus pulmonary syndrome10.4
6omsk hemorrhagic fever10.1
7rift valley fever10.1
8argentine hemorrhagic fever10.1
9lujo hemorrhagic fever10.1
10chapare hemorrhagic fever10.1
11alkhurma hemorrhagic fever10.1
12crimean-congo hemorrhagic fever10.1
13dengue hemorrhagic fever10.1
14balkan hemorrhagic fever10.1
15capillary leak syndrome10.1

Graphical network of diseases related to Viral Hemorrhagic Fever:



Diseases related to viral hemorrhagic fever

Clinical Features for Viral Hemorrhagic Fever

Sources:
49Orphanet
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Symptoms:

49 (show all 26)
  • fever/chilling
  • asthenia/fatigue/weakness
  • conjunctival injection/chemosis/red eye
  • purpura/petichiae
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • acute abdominal pain/colic
  • acute diarrhea
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • thoracic/chest pain
  • metrorrhagia/menorrhagia/hemorrhagic cycles/hyper/poly/spanio/dysmenorrhea
  • facial pain/cephalalgia/migraine
  • myalgia/muscular pain
  • articular/joint pain/arthralgia
  • leukopenia/hypoleukocytosis
  • thrombocytopenia/thrombopenia
  • epistaxis/nose bleeding
  • gingivorrhagia/gingival bleeding
  • mucosal/cutaneous hemorrhage
  • spontaneous abortions
  • hearing loss/hypoacusia/deafness
  • bronchiolitis
  • retrobulbar optic neuritis
  • encephalitis
  • seizures/epilepsy/absences/spasms/status epilepticus
  • obnubilation/coma/lethargia/desorientation
  • early death/lethality

Drugs & Therapeutics for Viral Hemorrhagic Fever

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Viral Hemorrhagic Fever

Drug clinical trials:

Search ClinicalTrials for Viral Hemorrhagic Fever

Search NIH Clinical Center for Viral Hemorrhagic Fever

Search CenterWatch for Viral Hemorrhagic Fever

Genetic Tests for Viral Hemorrhagic Fever

Anatomical Context for Viral Hemorrhagic Fever

Sources:
33MalaCards
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MalaCards organs/tissues related to Viral Hemorrhagic Fever:

33
Kidney, Liver, T cells, B cells

Animal Models for Viral Hemorrhagic Fever or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Viral Hemorrhagic Fever

Sources:
51PubMed
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Articles related to Viral Hemorrhagic Fever:

(show top 50)    (show all 73)
idTitleAuthorsYear
1
The pathogenesis of severe Fever with thrombocytopenia syndrome virus infection in alpha/beta interferon knockout mice: insights into the pathologic mechanisms of a new viral hemorrhagic Fever. (24257618)
2014
2
Genomic analysis of filoviruses associated with four viral hemorrhagic fever outbreaks in Uganda and the Democratic Republic of the Congo in 2012. (23711383)
2013
3
Viral hemorrhagic fever viruses. (24314803)
2013
4
Outbreak of viral hemorrhagic fever caused by dengue virus type 3 in Al-Mukalla, Yemen. (23497142)
2013
5
Alkhurma viral hemorrhagic fever virus: proposed guidelines for detection, prevention, and control in Saudi Arabia. (22860139)
2012
6
In situ rolling circle amplification detection of Crimean Congo hemorrhagic fever virus (CCHFV) complementary and viral RNA. (22341783)
2012
7
Comparison of Hantaan and Seoul viral infections among patients with hemorrhagic fever with renal syndrome (HFRS) in Heilongjiang, China. (21428852)
2011
8
Hantavirus-specific IgA in saliva and viral antigen in the parotid gland in patients with hemorrhagic fever with renal syndrome. (21360546)
2011
9
Simian hemorrhagic fever virus infection of rhesus macaques as a model of viral hemorrhagic fever: clinical characterization and risk factors for severe disease. (22014505)
2011
10
Prompt administration of Crimean-Congo hemorrhagic fever (CCHF) virus hyperimmunoglobulin in patients diagnosed with CCHF and viral load monitorization by reverse transcriptase-PCR. (21937830)
2011
11
Assessing changes in vascular permeability in a hamster model of viral hemorrhagic fever. (20846417)
2010
12
Fatal spotted fever group rickettsiosis due to Rickettsia conorii conorii mimicking a hemorrhagic viral fever in a South African traveler in Brazil. (21771523)
2010
13
Reappearance of viral hemorrhagic fever with renal syndrome in northwestern Greece. (19926507)
2010
14
Gene expression in primate liver during viral hemorrhagic fever. (19216742)
2009
15
Interferon and cytokine responses to Crimean Congo hemorrhagic fever virus; an emerging and neglected viral zonoosis. (19027345)
2008
16
Viral load as predictor of Crimean-Congo hemorrhagic fever outcome. (18217568)
2007
17
Viral load and Crimean-Congo hemorrhagic fever. (18044055)
2007
18
Slower rates of clearance of viral load and virus-containing immune complexes in patients with dengue hemorrhagic fever. (16983615)
2006
19
Viral hemorrhagic fever - an ICU perspective. (16827967)
2006
20
MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fever. (16704825)
2006
21
Role of specific CD8+ T cells in the severity of a fulminant zoonotic viral hemorrhagic fever, hantavirus pulmonary syndrome. (14978138)
2004
22
Correction: Stampidine prevents mortality in an experimental mouse model of viral hemorrhagic fever caused by lassa virus. (15171793)
2004
23
Other viral bioweapons: Ebola and Marburg hemorrhagic fever. (15207310)
2004
24
Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome. (15047846)
2004
25
High levels of plasma dengue viral load during defervescence in patients with dengue hemorrhagic fever: implications for pathogenesis. (12573578)
2003
26
Treating viral hemorrhagic fever. (14600838)
2003
27
Implementation of the Canadian contingency plan for a case of suspected viral hemorrhagic fever. (12725358)
2003
28
Viral hemorrhagic fever--a vascular disease? (12783108)
2003
29
Viral hemorrhagic fevers including hantavirus pulmonary syndrome in the Americas. (12489291)
2002
30
False-negative results of PCR assay with plasma of patients with severe viral hemorrhagic fever. (12409441)
2002
31
Mitogen therapy for biological warfare/terrorist attacks and viral hemorrhagic fever control. (11915170)
2002
32
Viral hemorrhagic fever in Pakistan: awareness among health care personnel. (12174494)
2002
33
Viral hemorrhagic fever hazards for travelers in Africa. (11595975)
2001
34
Relationship between the clinical features and the viral antigen in the extremity blood of the patients with hemorrhagic fever with renal syndrome. (12840882)
1999
35
Effects of viral hemorrhagic fever inactivation methods on the performance of rapid diagnostic tests for Plasmodium falciparum. (9815250)
1998
36
Viral hemorrhagic fever: Admission policy for hospitals in the Arabian Peninsula. (17341986)
1998
37
From the Centers for Disease Control and Prevention. Update: outbreak of Ebola viral hemorrhagic fever--Zaire, 1995. (7769766)
1995
38
Outbreak of Ebola viral hemorrhagic fever--Zaire, 1995. (7739512)
1995
39
Update: outbreak of Ebola viral hemorrhagic fever--Zaire, 1995. (7746265)
1995
40
Localization of Hantaan viral envelope glycoproteins by monoclonal antibodies in renal tissues from patients with Korean hemorrhagic fever H. (7692720)
1993
41
Antibodies against dengue viral proteins in primary and secondary dengue hemorrhagic fever. (2063952)
1991
42
Hemorrhagic fever with renal syndrome. Separation of human peripheral blood T and B cells and detection of viral antigen. (1972048)
1990
43
Hemorrhagic fever with renal syndrome: separation of human peripheral blood T and B cells and detection of viral antigen. (2577361)
1989
44
Inhibition of Crimean-Congo hemorrhagic fever viral infectivity yields in vitro by ribavirin. (2510529)
1989
45
Pathogenesis of viral hemorrhagic fevers: Rift Valley fever and Lassa fever contrasted. (2665011)
1989
46
Viral strain dependent differences in experimental Argentine hemorrhagic fever (Junin virus) infection of guinea pigs. (2846464)
1988
47
Experimental Argentine hemorrhagic fever in rhesus macaques: viral strain-dependent clinical response. (2989384)
1985
48
Crossed immunoelectrophoresis for the detection of split products of the third complement component in dengue hemorrhagic fever. II. In vitro activation by dengue viral antigen. (6391227)
1984
49
Nosocomial outbreak of viral hemorrhagic fever caused by Crimean Hemorrhagic fever-Congo virus in Pakistan, January 1976. (7435795)
1980
50
A report on dengue hemorrhagic fever patients with viral isolation. (1196649)
1975

Genetic Variations for Viral Hemorrhagic Fever

Expression for genes affiliated with Viral Hemorrhagic Fever

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Viral Hemorrhagic Fever

Search GEO for disease gene expression data for Viral Hemorrhagic Fever.

Pathways for genes affiliated with Viral Hemorrhagic Fever

Compounds for genes affiliated with Viral Hemorrhagic Fever

GO Terms for genes affiliated with Viral Hemorrhagic Fever

Products for genes affiliated with Viral Hemorrhagic Fever

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Viral Hemorrhagic Fever

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet