MCID: VRL011
MIFTS: 59

Viral Infectious Disease

Categories: Infectious diseases, Respiratory diseases

Aliases & Classifications for Viral Infectious Disease

Summaries for Viral Infectious Disease

MedlinePlus : 41 viruses are very tiny germs. they are made of genetic material inside of a protein coating. viruses cause familiar infectious diseases such as the common cold, flu and warts. they also cause severe illnesses such as hiv/aids, smallpox, and ebola. viruses are like hijackers. they invade living, normal cells and use those cells to multiply and produce other viruses like themselves. this can kill, damage, or change the cells and make you sick. different viruses attack certain cells in your body such as your liver, respiratory system, or blood. when you get a virus, you may not always get sick from it. your immune system may be able to fight it off. for most viral infections, treatments can only help with symptoms while you wait for your immune system to fight off the virus. antibiotics do not work for viral infections. there are antiviral medicines to treat some viral infections. vaccines can help prevent you from getting many viral diseases.

MalaCards based summary : Viral Infectious Disease, also known as arbovirus infections, is related to tick-borne encephalitis and bolivian hemorrhagic fever, and has symptoms including fever, pruritus and pathological conditions, signs and symptoms. An important gene associated with Viral Infectious Disease is TLR9 (Toll Like Receptor 9), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Entecavir and Lamivudine have been mentioned in the context of this disorder. Affiliated tissues include liver, testes and t cells, and related phenotypes are cellular and hematopoietic system

Disease Ontology : 12 A disease by infectious agent that results_in infection, has material basis in Viruses.

Wikipedia : 72 A viral disease (or viral infection) occurs when an organism\'s body is invaded by pathogenic viruses,... more...

Related Diseases for Viral Infectious Disease

Diseases related to Viral Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 303)
id Related Disease Score Top Affiliating Genes
1 tick-borne encephalitis 32.8 CD40LG MX1 TNF
2 bolivian hemorrhagic fever 32.6 IFNG IL2 TNF
3 alkhurma hemorrhagic fever 32.6 CD40LG IL10 TNF
4 louping ill 32.6 IFNG IL2 TNF
5 newcastle disease 32.6 CD40LG CXCL10 IFNA2
6 dengue disease 32.6 IFNG IL10 TLR9 TNF
7 plantar wart 32.5 IFNG IL10 IL2 TNF
8 zika virus infection 12.3
9 immunodeficiency 31b, mycobacterial and viral infections, autosomal recessive 12.2
10 chronic active epstein-barr virus infection 12.2
11 x-linked magnesium deficiency with epstein-barr virus infection and neoplasia 12.2
12 immunodeficiency, x-linked, with magnesium defect, epstein-barr virus infection and neoplasia 12.1
13 congenital herpes simplex virus infection 12.0
14 hendra virus infection 12.0
15 primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection 11.9
16 congenital epstein-barr virus infection 11.9
17 lethal idiopathic viral infection 11.9
18 simian b virus infection 11.9
19 autoimmune lymphoproliferative syndrome, type iib 11.6
20 x-linked intellectual disability-precocious puberty-obesity syndrome 11.2 DDX58 IFIH1
21 hyperinsulinism due to short chain 3-hydroxylacyl-coa dehydrogenase deficiency 11.1 IFNA1 IFNB1
22 cellulitis 11.1 IFNB1 IRF3 TLR7
23 turner syndrome 11.1 CCR5 DDX58 TLR9
24 scirrhous adenocarcinoma 11.1 IL2 TNF
25 bulbospinal polio 11.1 IFNG IL2 TLR3
26 central nervous system leiomyosarcoma 11.1 CD40LG TLR9 TNF
27 pure autonomic failure 11.1 IL10 TNF
28 myeloid and lymphoid neoplasms with eosinophilia and abnormalities of pdgfra, pdgfrb, and fgfr1 11.1 CCR5 IFNG TNF
29 spoan syndrome 11.1 CD40LG IFNB1
30 gonococcal endophthalmia 11.1 CCR5 IRF7 TLR9
31 secretory diarrhea 11.1 CD40LG DDX58 IFNB1 IRF3
32 autoimmune polyglandular syndrome type 3 11.1 IFNG IL2 TNF
33 dumping syndrome 11.1 CD40LG IFNG IL10
34 balkan hemorrhagic fever 11.1 CD40LG IL10
35 testicular infarct 11.1 CD40LG TLR9 TNF
36 tetrahydrobiopterin-responsive hyperphenylalaninemia/phenylketonuria 11.1 TLR3 TLR7 TLR9
37 centronuclear myopathy 5 11.1 CD40LG IFNG IL10
38 acute necrotizing encephalopathy type 1 11.1 IFNG IL2 TLR9
39 acute ackee fruit intoxication 11.1 IL10 TNF
40 nuchal bleb, familial 11.1 CD40LG IFNA1 IFNA2
41 amyotrophic lateral sclerosis type 10 11.1 IFNG IL2 TNF
42 lymphocytic colitis 11.1 IFNG IL2 TNF
43 parametritis 11.0 IFNG IL2 TNF
44 graft-versus-host disease, protection against 11.0 IFNG IL10 IL2
45 non-suppurative otitis media 11.0 IFNA1 IFNB1 TLR7
46 sirenomelia 11.0 DDX58 IFIH1
47 spastic paraplegia 15, autosomal recessive 11.0 IFNA1 IFNB1 MX1
48 acute vascular insufficiency of intestine 11.0 CD40LG IFNG TLR9 TNF
49 spindle cell hemangioma 11.0 IFNG IL10 TNF
50 early-onset zonular cataract 11.0 IFNG IL10 TNF

Graphical network of the top 20 diseases related to Viral Infectious Disease:



Diseases related to Viral Infectious Disease

Symptoms & Phenotypes for Viral Infectious Disease

UMLS symptoms related to Viral Infectious Disease:


fever, pruritus, pathological conditions, signs and symptoms

MGI Mouse Phenotypes related to Viral Infectious Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.25 TNF CCR5 CD40LG CXCL10 DDX58 IFIH1
2 hematopoietic system MP:0005397 10.24 MAVS TLR3 TLR7 TLR9 TNF CCR5
3 homeostasis/metabolism MP:0005376 10.22 CCR5 CD40LG CXCL10 DDX58 IFIH1 IFNB1
4 immune system MP:0005387 10.16 CCR5 CD40LG CXCL10 DDX58 IFIH1 IFNB1
5 digestive/alimentary MP:0005381 10.01 TLR9 TNF CCR5 DDX58 IFNG IL10
6 mortality/aging MP:0010768 9.8 CCR5 CD40LG CXCL10 DDX58 IFIH1 IFNG
7 liver/biliary system MP:0005370 9.76 CCR5 DDX58 IFIH1 IFNG IL10 IL2
8 neoplasm MP:0002006 9.28 TLR3 TNF CCR5 DDX58 IFNB1 IFNG

Drugs & Therapeutics for Viral Infectious Disease

Drugs for Viral Infectious Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1197)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Entecavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 142217-69-4 153941
2
Lamivudine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 134678-17-4 60825
3
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
4
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
5
Ethiodized oil Approved Phase 4,Phase 2 8008-53-5
6
Telbivudine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 3424-98-4 159269
7
Isoniazid Approved Phase 4,Phase 3,Phase 2,Phase 1 54-85-3 3767
8
Amantadine Approved Phase 4,Phase 3,Phase 1,Phase 2 768-94-5 2130
9
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
10
Peginterferon alfa-2a Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 198153-51-4 5360545
11
Ribavirin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 36791-04-5 37542
12
Pentoxifylline Approved, Investigational Phase 4,Phase 3,Phase 1 6493-05-6 4740
13
Peginterferon alfa-2b Approved Phase 4,Phase 3,Phase 2,Phase 1 99210-65-8, 215647-85-1
14
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
15
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
16
Oseltamivir Approved Phase 4,Phase 3,Phase 2,Phase 1 204255-11-8, 196618-13-0 65028
17
Aluminum hydroxide Approved Phase 4,Phase 2,Phase 3,Phase 1 21645-51-2
18
Neomycin Approved, Vet_approved Phase 4,Phase 1,Phase 2 1404-04-2 8378
19
Efavirenz Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 154598-52-4 64139
20
Lopinavir Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 192725-17-0 92727
21
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1994-09-7, 94-09-7 2337
22
Basiliximab Approved, Investigational Phase 4,Phase 3,Phase 2 152923-56-3, 179045-86-4
23
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
24
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
25
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
26
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
27
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
28
Adefovir Dipivoxil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 142340-99-6 60871
29
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
30
Metformin Approved Phase 4,Phase 2,Phase 3,Phase 1 657-24-9 14219 4091
31
Pioglitazone Approved, Investigational Phase 4,Phase 3,Phase 2 111025-46-8 4829
32
Montelukast Approved Phase 4,Phase 3,Phase 2 158966-92-8 5281040
33
Candesartan Approved Phase 4 139481-59-7 2541
34
Lercanidipine Approved, Investigational Phase 4 100427-26-7 65866
35
Emtricitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 143491-57-0 60877
36
Abacavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 136470-78-5 65140 441300
37 Dolutegravir Approved Phase 4,Phase 3,Phase 2,Phase 1 1051375-16-6 54726191
38
Nitazoxanide Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 55981-09-4 41684
39
Darunavir Approved Phase 4,Phase 3,Phase 2,Phase 1 635728-49-3, 206361-99-1 213039
40
Maraviroc Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 376348-65-1 3002977
41
Ritonavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 155213-67-5 392622
42
Insulin Glargine Approved Phase 4 160337-95-1
43
Insulin-glulisine Approved Phase 4 207748-29-6
44
Zinc Approved Phase 4,Phase 2,Phase 3,Phase 1 7440-66-6 32051 23994
45
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 1 51-43-4 5816
46 Racepinephrine Approved Phase 4,Phase 2,Phase 1
47
Dimenhydrinate Approved Phase 4 523-87-5 441281
48
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 124-94-7 31307
49
Foscarnet Approved Phase 4,Phase 3,Phase 2,Phase 1 63585-09-1, 4428-95-9 3415
50
Ganciclovir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 82410-32-0 3454

Interventional clinical trials:

(show top 50) (show all 10000)

id Name Status NCT ID Phase Drugs
1 Study of Immune Responses After Vaccination Against Seasonal Influenza Virus and Against Influenza H1N1-v Pandemic Virus in a Medical Staff. Unknown status NCT01063608 Phase 4
2 Efficacy of Antiviral Therapy After Radical Resection for Hepatitis B Virus-Related Hepatocellular Carcinoma Unknown status NCT00768157 Phase 4 antiviral treatment (lamivudine or entecavir)
3 Hepatitis C in Renal Transplant Recipients Unknown status NCT02108301 Phase 4 tacrolimus-cyclosporine A
4 Synergistic Treatment for Hepatocellular Carcinoma (HCC) Using Transcatheter Arterial Chemoembolization (TACE) With Anti-hepatitis B Virus (Anti-HBV) Therapy Unknown status NCT01102335 Phase 4 Telbivudine
5 Diagnosis and Treatment of Co-infection With Human Immunodeficiency Virus /Latent Tuberculosis Infection (HIV/TBL) Unknown status NCT01875952 Phase 4 Isoniazid
6 Peginterferon Alfa-2a, Ribavirin, Amantadine/Placebo in Hepatitis C Virus (HCV)-Genotype-1-Infection (PRAMA) Unknown status NCT00127777 Phase 4 Amantadine sulphate (in addition to standard treatment)
7 The Impact of Vitamin on the Clinical Course in Cases Infected by Novel H1N1 Influenza Virus A Unknown status NCT01127282 Phase 4 Vitamin (vitamin A 15 mg,C 500 mg, E 400IU);Placebo (digestive tablet)
8 Efficacy of PTX+IFN Alpha+ RBV on Hepatitis C Virus Coinfected HIV Patients Unknown status NCT02008214 Phase 4 Pentoxifylline;Placebo
9 Topical Cyclosporine for the Treatment of Dry Eye in Patients Infected With the Human Immunodeficiency Virus Unknown status NCT00797030 Phase 4 cyclosporine and sodium carboximethycellulose;sodium carboximethycellulose
10 Entecavir for Chronic Hepatitis B Patients With Persistently Normal ALT Unknown status NCT01833611 Phase 4 Entecavir;placebo
11 Entecavir Plus Tenofovir Combination in Subjects With Multi-drug Resistant Chronic Hepatitis B Virus Infection Unknown status NCT01594905 Phase 4 Entecavir + Tenofovir (MDR group)
12 Hepatitis B Virus (HBV) Antibody (Anti-HBs) Booster Program for the Production of Hepatitis B Immune Globulin (HBIG) Unknown status NCT01311674 Phase 4
13 Antibody Response of a Boosted Japanese Encephalitis Chimeric Virus Vaccine (JE-CV) in Children Unknown status NCT01954810 Phase 4
14 Entecavir for Patients With Decompensated Hepatitis B Virus (HBV)-Related Cirrhosis Unknown status NCT00663182 Phase 4 Entecavir
15 Comparison of the Cellular and the Humoral Immunogenicity, Safety of Different Trivalent Influenza Vaccines Unknown status NCT01119157 Phase 4
16 A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD) Unknown status NCT01731301 Phase 4 Ribavirin;Peginterferon;Boceprevir
17 Improved Prevention of Perinatal Hepatitis B Transmission Unknown status NCT01133184 Phase 4
18 Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls? Unknown status NCT01101750 Phase 4
19 Hansenula-derived Pegylated Interferon in Treatment of Patients With Chronic Hepatitis C Unknown status NCT01649245 Phase 4 Reiferon retard
20 The Effect and Safety of the Seasonal Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Not on Dialysis Unknown status NCT02105519 Phase 4
21 Phase IV Study to Evaluate the Efficacy/Safety to Extend Treatment and High Dose of Ribavirin in co-Infected Patients Unknown status NCT00526448 Phase 4 ribavirin;ribavirin;Peginterferon alfa-2a;epoetin beta
22 TO Compare the Triple Drug Therapy and Dual Therapy . Unknown status NCT02075242 Phase 4 Mycophenolate Mofetil;Tacrolimus
23 Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adults Unknown status NCT01811823 Phase 4
24 Chinese Medicinal Herbs Treatment on Novel Influenza A (H1N1)Pneumonia: Multi-centre, Prospective, Randomized Controlled Study Unknown status NCT00936013 Phase 4 oseltamivir;oseltamivir and chinese medicinal herbs
25 Immune Response After Human Papillomavirus Vaccination in Patients With Autoimmune Disease Unknown status NCT00815282 Phase 4 Human papilloma virus vaccine (cervarix)
26 Antiviral Therapy in Hepatitis B Virus (HBV)-Related Advanced Liver Disease Patients Unknown status NCT00823550 Phase 4 Entecavir;Lamivudine
27 High Intensity Focused Ultrasound Ablation Virus Myomectomy to Treat Uterine Fibroids Unknown status NCT01239641 Phase 4
28 Efficacy and Safety Study of Telbivudine to Prevent Perinatal Transmission Unknown status NCT00939068 Phase 4 Telbivudine
29 7-valent Pneumococcal Conjugated Vaccination Unknown status NCT00885625 Phase 4
30 Cellular Immunity in Adult Hepatitis B-vaccinated Serologic Non-responders Unknown status NCT01451801 Phase 4
31 Study to Evaluate the Non-inferiority of Cavir in HBeAg(+)Chronic Hepatitis B Patients Treated With Baraclude Unknown status NCT02523547 Phase 4 Cavir;Baraclude
32 Twinrix Alternative Schedule Study Unknown status NCT00216229 Phase 4
33 Adjusting Antiretroviral Therapy Dosage Using Therapeutic Drug Monitoring Unknown status NCT00836212 Phase 4 Reducing dose of Lopinavir;Reducing dose of efavirenz
34 Optimizing Treatment Programs for Chronic Kidney Disease-mineral and Bone Disorder and Malnutrition Unknown status NCT02005302 Phase 4 1,25(OH)2 Vitamin D3;Vitamin D2
35 Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporineversus an Immunosuppressive Regimen With Mycophenolic Acid and Unknown status NCT02328963 Phase 4 Everolimus;mycophenolic acid
36 The Self-Collection Study: a Study of Self-collected HPV Testing and Results Counseling Unknown status NCT01843478 Phase 4
37 Efficacy Optimizing Research of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy Unknown status NCT01341743 Phase 4 Entecavir;Entecavir, Adefovir;Entecavir, Adefovir
38 Using Entecavir to Reduce Hepatitis in Highly Viremic HBV Patients During Anti-tuberculous Treatment Unknown status NCT01724723 Phase 4 entecavir (BARACLUDE®)
39 A Trial To Study The Effect Of Lamivudine In Adult Patients Who Suffer From Chronic Hepatitis B Alone Unknown status NCT00354653 Phase 4 LAMIVUDINE
40 Cellular and Humoral Immunity in Elderly After Immunization With a Japanese Encephalitis Vaccine Unknown status NCT01398540 Phase 4
41 The Effects of Oral Hypoglycemic Agents on Chronic Hepatitis C Patients Receiving Peg-Intron Plus Ribavirin Unknown status NCT01025765 Phase 4 Pioglitazone;Acarbose;Metformin
42 Pegylated Interferon Alfa-2b Plus Ribavirin in Chronic Hepatitis B and Delta Unknown status NCT00117533 Phase 4 pegylated IFN alfa-2b plus ribavirin
43 Safety and Immunogenicity of Zostavax Vaccine in Patients Undergoing Living Donor Kidney Transplantation Unknown status NCT00940940 Phase 4
44 Montelukast for Persistent Cough in Young People and Adults Unknown status NCT01279668 Phase 4 Montelukast;Placebo
45 Pegylated-Interferon and Ribavirin Plus Metformin in the Treatment of Chronic HCV Infection and Insulin Resistance Unknown status NCT00370617 Phase 4 metformin
46 Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases Unknown status NCT01151644 Phase 4
47 Telbivudine Renoprotective Effect in Patients With the HBV-related Liver Cirrhosis: a Randomized Controlled Trial Unknown status NCT01799486 Phase 4 Telbivudine;Enecavir;Adefovir
48 Effects of Antihypertensive Treatment in HIV Infected Patients: Candesartan Versus Lercanidipine Unknown status NCT00564057 Phase 4 candesartan;lercanidipine
49 HIV Persistence and Viral Reservoirs Unknown status NCT01025427 Phase 4 Raltegravir, tenofovir/emtricitabine
50 Sustained Off-treatment Response After HBeAg Loss in Chronic Hepatitis B Patients Treated With Nucleos(t)Ide Analogues Unknown status NCT01911156 Phase 4 Continue NA treatment;Discontinue NA Treatment

Search NIH Clinical Center for Viral Infectious Disease

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: arbovirus infections

Genetic Tests for Viral Infectious Disease

Anatomical Context for Viral Infectious Disease

MalaCards organs/tissues related to Viral Infectious Disease:

39
Liver, Testes, T Cells, Kidney, Lung, Bone, B Cells

Publications for Viral Infectious Disease

Articles related to Viral Infectious Disease:

id Title Authors Year
1
Evolutionary analysis of the dynamics of viral infectious disease. ( 19564871 )
2009
2
Viral infectious disease and natural products with antiviral activity. ( 22504360 )
2007
3
IL12 in acute viral infectious disease. ( 8839166 )
1995

Variations for Viral Infectious Disease

Expression for Viral Infectious Disease

Search GEO for disease gene expression data for Viral Infectious Disease.

Pathways for Viral Infectious Disease

Pathways related to Viral Infectious Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 60)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
14.01 CCR5 CD40LG CXCL10 DDX58 IFIH1 IFNA1
2
Show member pathways
13.73 CCR5 CD40LG CXCL10 IFNA1 IFNA2 IFNB1
3
Show member pathways
13.48 CCR5 CD40LG CXCL10 IL10 IL2 TLR3
4
Show member pathways
13.43 CCR5 CD40LG CXCL10 DDX58 IFNA1 IFNA2
5
Show member pathways
13.35 IFNA1 IFNA2 IFNB1 IL2 IRF3 IRF7
6
Show member pathways
13.06 IFNA1 IFNA2 IFNB1 IRF3 IRF7 MAVS
7
Show member pathways
12.93 CD40LG IFNA1 IFNA2 IFNG IL10 IL2
8
Show member pathways
12.85 CXCL10 DDX58 IFIH1 IFNA1 IFNA2 IFNB1
9
Show member pathways
12.79 CXCL10 DDX58 IFIH1 IFNA1 IFNA2 IFNB1
10
Show member pathways
12.78 CD40LG IL2 TLR3 TLR7 TLR9 TNF
11 12.75 IFNA1 IFNA2 IFNB1 IL2 IRF3 MX1
12
Show member pathways
12.7 CD40LG IRF3 IRF7 TLR3 TLR7 TLR9
13
Show member pathways
12.67 CD40LG IFNG IL10 IL2 TNF
14
Show member pathways
12.64 DDX58 IFNA1 IFNA2 IFNB1 IFNG IRF3
15
Show member pathways
12.6 IFNA1 IFNA2 IFNB1 IFNG IL2 TNF
16
Show member pathways
12.55 CXCL10 IFNA1 IFNA2 IFNB1 IFNG IL10
17 12.53 CD40LG CXCL10 DDX58 IFIH1 IFNA1 IFNG
18
Show member pathways
12.52 DDX58 IFIH1 IRF3 IRF7 MAVS TLR3
19
Show member pathways
12.52 CCR5 CD40LG IFNG IL10 IL2 TNF
20 12.35 IFNA1 IFNA2 IFNB1 IFNG IL10 TLR9
21
Show member pathways
12.34 IFNA1 IFNA2 IFNB1 IFNG
22
Show member pathways
12.34 CCR5 CD40LG IFNG IL10 TNF
23 12.33 DDX58 IFNG IL10 IRF3
24
Show member pathways
12.31 IFNG IRF3 TLR3 TNF
25
Show member pathways
12.3 IFNA1 IFNA2 IFNB1 IFNG IL10 IL2
26 12.27 IFNG TLR3 TLR7 TLR9 TNF
27
Show member pathways
12.27 CXCL10 IFNB1 IFNG TLR7 TLR9 TNF
28 12.24 IFNA1 IFNA2 IFNB1 IRF3 IRF7
29
Show member pathways
12.09 IL2 TLR3 TLR7 TLR9
30 12.09 DDX58 IFNA1 IFNA2 IFNB1 IRF3 IRF7
31 12.08 IFNA2 IFNG IL10 IL2 TNF
32 12.07 CXCL10 IFNG IL2 TNF
33
Show member pathways
12.07 IFNG IL10 IL2 TLR3 TLR7 TLR9
34 12 CCR5 IFNA1 IFNA2 IFNB1 IFNG IL10
35
Show member pathways
11.99 IFNG TLR3 TLR7 TLR9
36 11.88 IFNG IL10 IL2 TNF
37
Show member pathways
11.85 CD40LG IFNG IL2 TNF
38 11.85 IFNA2 IFNB1 IFNG IL10 IL2 TLR7
39 11.83 TLR3 TLR7 TLR9
40 11.81 CD40LG IL10 TLR9 TNF
41 11.79 IFNB1 IL10 IRF7
42 11.78 IL10 IRF3 TNF
43
Show member pathways
11.76 CD40LG IFNG IL2 TNF
44
Show member pathways
11.68 IFNG IL2 TNF
45 11.66 CD40LG IFNG IL10 TLR9 TNF
46 11.63 CCR5 CXCL10 IL10 TNF
47 11.59 IFNG IL2 TNF
48 11.56 IFNG IL2 TNF
49 11.55 IFNG IL10 IL2
50
Show member pathways
11.53 IFNA1 IFNA2 IFNB1 IFNG IL10 IL2

GO Terms for Viral Infectious Disease

Cellular components related to Viral Infectious Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.9 CD40LG CXCL10 IFNA1 IFNA2 IFNB1 IFNG
2 endosome membrane GO:0010008 9.67 IRF7 TLR3 TLR7 TLR9
3 external side of plasma membrane GO:0009897 9.65 CCR5 CD40LG CXCL10 IFNG TNF
4 extracellular space GO:0005615 9.65 CD40LG CXCL10 IFNA1 IFNA2 IFNB1 IFNG
5 early phagosome GO:0032009 9.32 TLR7 TLR9
6 endolysosome membrane GO:0036020 8.8 TLR3 TLR7 TLR9

Biological processes related to Viral Infectious Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 82)
id Name GO ID Score Top Affiliating Genes
1 type I interferon signaling pathway GO:0060337 9.99 IFNA1 IFNA2 IFNB1 IRF3 IRF7 MX1
2 positive regulation of inflammatory response GO:0050729 9.98 IL2 TLR3 TLR7 TLR9
3 positive regulation of type I interferon production GO:0032481 9.97 IRF3 IRF7 MAVS TLR3
4 humoral immune response GO:0006959 9.97 IFNA1 IFNA2 IFNB1 IFNG TNF
5 positive regulation of tumor necrosis factor production GO:0032760 9.96 IFNG MAVS TLR3 TLR9
6 positive regulation of interleukin-6 production GO:0032755 9.96 DDX58 TLR3 TLR7 TLR9 TNF
7 negative regulation of viral genome replication GO:0045071 9.95 IFNB1 MAVS MX1 TNF
8 negative regulation of type I interferon production GO:0032480 9.94 DDX58 IFIH1 IRF3 MAVS
9 positive regulation of JNK cascade GO:0046330 9.93 TLR3 TLR9 TNF