MCID: VRL005
MIFTS: 47

Viral Pneumonia malady

Respiratory diseases category
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Summaries for Viral Pneumonia

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Sources:
8Disease Ontology, 65Wikipedia, 33MalaCards
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Disease Ontology:8 A pneumonia described as an inflammatory illness of the lung commonly caused by viruses such as influenza virus, parainfluenza, adenovirus, rhinovirus, herpes simplex virus, respiratory syncytial virus, hantavirus, and cytomegalovirus.

MalaCards: Viral Pneumonia, also known as pneumonia, viral, is related to pneumonia and viral meningitis. An important gene associated with Viral Pneumonia is FCRL6 (Fc receptor-like 6), and among its related pathways are Complement Pathway and IL6-mediated signaling events. The compounds alpha-hydroxybutyrate and lactulose have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and endothelial.

Wikipedia:65 Viral pneumonia is a pneumonia caused by a virus. Viruses are one of the two major causes of pneumonia,... more...

Aliases & Classifications for Viral Pneumonia

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8Disease Ontology, 10DISEASES, 62UMLS, 58SNOMED-CT, 27ICD9CM, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

viral pneumonia 8 10
pneumonia, viral 62


External Ids:

Disease Ontology8 DOID:10533
ICD9CM27 480, 480.9
MeSH35 D011024
ICD1025 J12

Related Diseases for Viral Pneumonia

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Pneumonia family:

viral pneumonia

Diseases related to Viral Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 109)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia31.5FCRL6, IL6, CRP, CR1
2viral meningitis30.3CRP, IL6
3vascular disease30.1IL6
4malaria30.1CR1, ALB
5respiratory failure30.0CRP, IL6
6adult respiratory distress syndrome30.0IL6, CR1
7synovitis30.0IL6, CRP
8sepsis29.9IL6, ALB, CRP, CR1
9influenza10.6
10herpes simplex10.4
11bronchiolitis10.2
12measles10.2
13endotheliitis10.2
14bacteriuria10.1CRP
15cardiac rupture10.1CHKB
16pericardial effusion10.1CHKB
17neuroleptic malignant syndrome10.1CHKB
18pyelonephritis10.1CRP
19aortic aneurysm10.1CRP
20cholecystitis10.1GPT
21fatty liver disease10.1CRP
22crohn's disease10.1ALB, CRP
23choledocholithiasis10.1SLC17A5, GPT
24scrub typhus10.1SLC17A5, GPT
25pyridoxine deficiency10.1SLC17A5, GPT
26obstructive jaundice10.1GPT, SLC17A5
27kawasaki disease10.1GPT, CRP
28hellp syndrome10.1SLC17A5, GPT
29alcohol abuse10.0GPT, SLC17A5
30splenomegaly10.0SLC17A5, GPT
31wilson disease10.0SLC17A5, GPT
32congenital stationary night blindness, type 1f10.0SLC17A5, GPT
33bacterial meningitis10.0CRP, CR1
34reactive arthritis10.0CRP, CR1
35ulcerative colitis10.0CRP, ALB
36metabolic acidosis10.0CHKB, ALB
37autoimmune hepatitis10.0SLC17A5, GPT
38hyperhomocysteinemia10.0ALB, CRP
39membranous glomerulonephritis10.0ALB, CR1
40adult-onset still's disease10.0IL6, CRP
41myositis10.0CHKB, SLC17A5
42viral hepatitis10.0GPT, SLC17A5
43chorioamnionitis10.0IL6, CRP
44pulmonary disease, chronic obstructive10.0CRP, IL6
45eye disease10.0CRP, IL6
46juvenile rheumatoid arthritis10.0IL6, CRP
47lupus nephritis10.0CR1, ALB
48familial hyperlipidemia10.0SLC17A5, CRP, GPT
49acute kidney failure10.0GPT, CHKB, ALB
50rheumatic disease10.0CR1, CRP

Graphical network of the top 20 diseases related to Viral Pneumonia:



Diseases related to viral pneumonia

Symptoms for Viral Pneumonia

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Drugs & Therapeutics for Viral Pneumonia

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Viral Pneumonia

Search NIH Clinical Center for Viral Pneumonia

Genetic Tests for Viral Pneumonia

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Anatomical Context for Viral Pneumonia

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33MalaCards
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MalaCards organs/tissues related to Viral Pneumonia:

33
Lung, Testes, Endothelial, Kidney, Monocytes

Animal Models for Viral Pneumonia or affiliated genes

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Publications for Viral Pneumonia

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Sources:
52PubMed
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Articles related to Viral Pneumonia:

(show top 50)    (show all 124)
idTitleAuthorsYear
1
Influenza and endemic viral pneumonia. (24094391)
2013
2
Are statins beneficial for viral pneumonia? (23633609)
2013
3
Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia. (23344833)
2013
4
A Patient who Survived Primary Seasonal Influenza Viral Pneumonia: Histologic Findings Obtained via Bronchoscopy. (24334588)
2013
5
Predictors of viral pneumonia: the need for viral testing in all patients hospitalized for nursing home-acquired pneumonia. (23441872)
2013
6
H7N9 viral pneumonia: asymmetric and irregular changes on computed tomography. (24342341)
2013
7
Clinical significance of pleural effusion in the new influenza A (H1N1) viral pneumonia in children and adolescent. (22028096)
2012
8
Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque. (22491448)
2012
9
Role of procalcitonin and C-reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia. (21668682)
2011
10
Viral pneumonia. (21435708)
2011
11
Case of the month #165: Swine-origin influenza A (H1N1) viral pneumonia presenting as crazy-paving on computed tomography: case report and literature review. (20850032)
2010
12
Epidemic viral pneumonia. (20087179)
2010
13
Mycoplasma pneumoniae pneumonia, bacterial pneumonia and viral pneumonia. (21140042)
2010
14
H1N1 pandemic flu found to cause viral pneumonia in severe cases, says WHO. (19843570)
2009
15
Viral pneumonia: epidemiological, clinical, pathophysiological and therapeutic aspects. (19820817)
2009
16
Viral pneumonia in older adults. (16421796)
2006
17
Measurement of complement receptor 1 on neutrophils in bacterial and viral pneumonia. (16433910)
2006
18
Viral pneumonia: coinfection of cytomegalovirus and herpes simplex virus. (15942111)
2005
19
Non-specific host response markers in the differentiation between pneumococcal and viral pneumonia: what is the most accurate combination? (15491381)
2004
20
Comparison of serum biochemical features between SARS and other viral pneumonias]. (15535901)
2004
21
Herpes simplex viral pneumonia after coronary artery bypass grafting. (12723587)
2003
22
8-nitroguanosine formation in viral pneumonia and its implication for pathogenesis. (12522148)
2003
23
Use of a large national database for comparative evaluation of the effect of a bronchiolitis/viral pneumonia clinical care guideline on patient outcome and resource utilization. (12413334)
2002
24
Viral pneumonia as a serious complication of etanercept therapy. (11790076)
2002
25
Plasma endothelin-1 in infants and young children with acute bronchiolitis and viral pneumonia. (12744623)
2002
26
Tumor necrosis factor as a mediator of inflammation in influenza A viral pneumonia. (8559046)
1995
27
Nosocomial viral pneumonia in the intensive care unit. (7768085)
1995
28
Herpes simplex viral pneumonia in the postthoracotomy patient. (7656651)
1995
29
Replication of equid herpesvirus 4 in endothelial cells and synovia of a field case of viral pneumonia and synovitis in a foal. (7769144)
1995
30
Experimental transmission of an apparent viral pneumonia in conventional and gnotobiotic pigs. (8465501)
1993
31
Bronchoalveolar lavage cell analysis in measles viral pneumonia. (8112435)
1993
32
Intratracheal surfactant administration restores gas exchange in experimental adult respiratory distress syndrome associated with viral pneumonia. (1850209)
1991
33
Viral pneumonia in recipients of solid organ transplants. (2160718)
1990
34
Viral pneumonia attenuates adenylate cyclase but not beta-adrenergic receptors in murine lung. (2557784)
1989
35
Amelioration of established Sendai viral pneumonia in the nude mouse using a monoclonal antibody to the virus fusion protein. (2557882)
1989
36
Diagnosis of viral pneumonia. (2840725)
1988
37
The participation of antiviral immune mechanisms in alveolar macrophage dysfunction during viral pneumonia. (6871495)
1983
38
Pulmonary inflammatory responses during viral pneumonia and secondary bacterial infection. (6305835)
1983
39
Necrotising aspergillosis complicating fulminating viral pneumonia. (6992331)
1980
40
Alterations in lung macrophage antimicrobial activity associated with viral pneumonia. (232689)
1979
41
Alterations in lung macrophage immune receptor(s) activity associated with viral pneumonia. (229220)
1979
42
Clinical course, management, and long-term sequelae of respiratory failure due to influenza viral pneumonia. (894855)
1977
43
Severe viral pneumonia in young adults. (776544)
1976
44
Intermittent positive-pressure therapy in treatment of viral pneumonia in a horse. (4609034)
1974
45
The effect of air ions on bacterial and viral pneumonia in mice. (5490693)
1970
46
Possible occurrence of viral pneumonia in indigenous sheep and goats--a morphological study of pneumonic lung lesions. (5815284)
1969
47
Pulmonary calcification in viral pneumonia. (5784985)
1969
48
Influenza viral pneumonia of human beings. (13711552)
1960
49
Viral pneumonia of the mother with hemorrhagic otitis in the fetus. (14405210)
1960
50
Viral pneumonia. (18909867)
1948

Variations for Viral Pneumonia

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Expression for genes affiliated with Viral Pneumonia

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Viral Pneumonia

Search GEO for disease gene expression data for Viral Pneumonia.

Pathways for genes affiliated with Viral Pneumonia

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Sources:
50PathCards, 53QIAGEN, 60Thomson Reuters, 55Reactome, 57SinoBiological, 38NCBI BioSystems Database, 30KEGG, 12EMD Millipore
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Pathways related to Viral Pneumonia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Immune response Alternative complement pathway60
Immune response Lectin Induced complement pathway60
Immune response Classic complement pathway60
9.6CR1, CRP
29.5IL6, CRP
39.3CR1, IL6
49.3CR1, IL6
59.3CRP, ALB
69.0CD3D, CR1, IL6
7
Show member pathways
thioredoxin pathway38
8.7CRP, ALB, IL6

Compounds for genes affiliated with Viral Pneumonia

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Sources:
45Novoseek, 11DrugBank, 29IUPHAR, 51PharmGKB, 24HMDB, 61Tocris Bioscience
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Compounds related to Viral Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 148)
idCompoundScoreTop Affiliating Genes
1alpha-hydroxybutyrate459.7CHKB, SLC17A5, GPT
2lactulose459.6SLC17A5, CRP, GPT
3ezetimibe45 1110.4SLC17A5, CRP, GPT
4bezafibrate45 29 1111.3SLC17A5, CRP, CHKB, GPT
5malondialdehyde459.2GPT, CRP, SLC17A5, CHKB
6gamma globulin459.2CRP, SLC17A5, ALB
7hepaplastin459.2ALB, SLC17A5, GPT
8fluvastatin45 51 29 1112.0IL6, CRP, CHKB, GPT
9sevoflurane51 45 1111.0ALB, GPT, SLC17A5
10fenofibrate45 51 1111.0IL6, CRP, SLC17A5, GPT
11pravastatin45 51 29 24 1113.0CRP, IL6, CHKB, GPT
12pioglitazone29 45 51 1111.9GPT, CRP, IL6, SLC17A5
13isoflurane51 45 1110.9ALB, SLC17A5, GPT
14vitamin b6458.9CRP, SLC17A5, ALB
15phosphorus458.8SLC17A5, ALB, CHKB, GPT
16polyethylene glycol458.8SLC17A5, CRP, CHKB, ALB
17pyridoxal 5-phosphate458.8SLC17A5, ALB, GPT
18vitamin b12458.8ALB, SLC17A5, CRP, GPT
19alpha tocopherol458.8CRP, CHKB, GPT, ALB
20neopterin458.7CHKB, GPT, CRP, SLC17A5, IL6
21atorvastatin45 51 29 24 1112.7CRP, SLC17A5, IL6, GPT, CHKB
22simvastatin45 51 61 29 24 1113.7GPT, CHKB, CRP, IL6, SLC17A5
23thyroxine45 249.7CHKB, ALB, SLC17A5, GPT
24n acetylcysteine458.6CHKB, IL6, CRP, SLC17A5, GPT
25endotoxin458.6CRP, CHKB, SLC17A5, IL6, CR1
26ivig458.6IL6, ALB, CRP, GPT
27tacrolimus45 51 1110.6GPT, SLC17A5, ALB, CHKB
28cyclosporin a45 29 6110.4GPT, SLC17A5, CR1, IL6, CHKB
29urea45 24 1110.3SLC17A5, ALB, LCN1, CHKB, GPT
30vitamin a45 24 1110.3GPT, SLC17A5, LCN1, CRP, ALB
31rosiglitazone29 45 51 24 1112.2ALB, SLC17A5, GPT, CRP, IL6
32potassium45 24 1110.2GPT, LCN1, ALB, SLC17A5, CHKB
33iron45 249.1ALB, CRP, SLC17A5, LCN1, GPT
34hyaluronic acid45 249.1SLC17A5, ALB, LCN1, IL6, GPT
35vitamin d458.0CHKB, CR1, ALB, IL6, GPT
36uric acid45 249.0GPT, CHKB, LCN1, ALB, CRP, SLC17A5
37sodium45 248.9LCN1, ALB, CR1, GPT, SLC17A5
38aspartate457.9ALB, SLC17A5, LCN1, CHKB, GPT, CRP
39rosuvastatin45 51 29 1110.9GPT, CRP, SLC17A5, ALB, IL6, CHKB
40methotrexate51 45 119.9GPT, CHKB, SLC17A5, CRP, IL6, ALB
41fibrinogen457.9SLC17A5, IL6, CRP, ALB, CHKB, GPT
42magnesium45 24 119.6LCN1, CR1, GPT, ALB, SLC17A5
43testosterone45 61 24 1110.6CRP, IL6, CHKB, SLC17A5, ALB
44prednisolone45 29 119.4GPT, IL6, CHKB, ALB, CRP, CR1
45lactate457.4CHKB, GPT, ALB, CRP, SLC17A5, LCN1
46creatinine457.4CHKB, SLC17A5, GPT, IL6, LCN1, ALB
47cholesterol45 29 24 1110.4SLC17A5, ALB, LCN1, IL6, CHKB, GPT
48alanine457.3GPT, LCN1, IL6, CHKB, CRP, SLC17A5
49glucose457.3SLC17A5, ALB, IL6, CRP, CHKB, LCN1
50lipid457.3GPT, SLC17A5, CRP, ALB, LCN1, IL6

GO Terms for genes affiliated with Viral Pneumonia

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16Gene Ontology
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Cellular components related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.1CRP, ALB, LCN1, IL6

Biological processes related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1complement activation, classical pathwayGO:0069589.6CR1, CRP
2negative regulation of lipid storageGO:0108889.5CRP, IL6
3defense response to Gram-positive bacteriumGO:0508309.5CRP, IL6
4acute-phase responseGO:0069539.2CRP, IL6
5retina homeostasisGO:0018959.0LCN1, ALB

Molecular functions related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1pyridoxal phosphate bindingGO:0301709.2ALB, GPT

Products for genes affiliated with Viral Pneumonia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Viral Pneumonia

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet