MCID: VRL005
MIFTS: 47

Viral Pneumonia malady

Respiratory diseases category

Summaries for Viral Pneumonia

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9Disease Ontology, 66Wikipedia, 34MalaCards
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Disease Ontology:9 A pneumonia described as an inflammatory illness of the lung commonly caused by viruses such as influenza virus, parainfluenza, adenovirus, rhinovirus, herpes simplex virus, respiratory syncytial virus, hantavirus, and cytomegalovirus.

MalaCards: Viral Pneumonia, also known as pneumonia, viral, is related to pneumonia and viral meningitis. An important gene associated with Viral Pneumonia is FCRL6 (Fc receptor-like 6), and among its related pathways are Complement Pathway and IL6-mediated signaling events. The compounds alpha-hydroxybutyrate and lactulose have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and endothelial.

Wikipedia:66 Viral pneumonia is a pneumonia caused by a virus. Viruses are one of the two major causes of pneumonia,... more...

Aliases & Classifications for Viral Pneumonia

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 28ICD9CM, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

viral pneumonia 9 11
pneumonia, viral 63


External Ids:

Disease Ontology9 DOID:10533
ICD9CM28 480, 480.9
MeSH36 D011024
ICD1026 J12

Related Diseases for Viral Pneumonia

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Sources:
18GeneCards, 19GeneDecks
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Diseases in the Pneumonia family:

viral pneumonia

Diseases related to Viral Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 109)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia31.5FCRL6, IL6, CRP, CR1
2viral meningitis30.3CRP, IL6
3vascular disease30.1IL6
4malaria30.1CR1, ALB
5respiratory failure30.0CRP, IL6
6adult respiratory distress syndrome30.0IL6, CR1
7synovitis30.0IL6, CRP
8sepsis29.9IL6, ALB, CRP, CR1
9influenza10.6
10herpes simplex10.4
11bronchiolitis10.2
12measles10.2
13endotheliitis10.2
14bacteriuria10.1CRP
15cardiac rupture10.1CHKB
16pericardial effusion10.1CHKB
17neuroleptic malignant syndrome10.1CHKB
18pyelonephritis10.1CRP
19aortic aneurysm10.1CRP
20cholecystitis10.1GPT
21fatty liver disease10.1CRP
22crohn's disease10.1ALB, CRP
23choledocholithiasis10.1SLC17A5, GPT
24scrub typhus10.1SLC17A5, GPT
25pyridoxine deficiency10.1SLC17A5, GPT
26obstructive jaundice10.1GPT, SLC17A5
27kawasaki disease10.1GPT, CRP
28hellp syndrome10.1SLC17A5, GPT
29alcohol abuse10.0GPT, SLC17A5
30splenomegaly10.0SLC17A5, GPT
31wilson disease10.0SLC17A5, GPT
32congenital stationary night blindness, type 1f10.0SLC17A5, GPT
33bacterial meningitis10.0CRP, CR1
34reactive arthritis10.0CRP, CR1
35ulcerative colitis10.0CRP, ALB
36metabolic acidosis10.0CHKB, ALB
37autoimmune hepatitis10.0SLC17A5, GPT
38hyperhomocysteinemia10.0ALB, CRP
39membranous glomerulonephritis10.0ALB, CR1
40adult-onset still's disease10.0IL6, CRP
41myositis10.0CHKB, SLC17A5
42viral hepatitis10.0GPT, SLC17A5
43chorioamnionitis10.0IL6, CRP
44pulmonary disease, chronic obstructive10.0CRP, IL6
45eye disease10.0CRP, IL6
46juvenile rheumatoid arthritis10.0IL6, CRP
47lupus nephritis10.0CR1, ALB
48familial hyperlipidemia10.0SLC17A5, CRP, GPT
49acute kidney failure10.0GPT, CHKB, ALB
50rheumatic disease10.0CR1, CRP

Graphical network of the top 20 diseases related to Viral Pneumonia:



Diseases related to viral pneumonia

Symptoms for Viral Pneumonia

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Drugs & Therapeutics for Viral Pneumonia

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Viral Pneumonia

Drug clinical trials:

Search ClinicalTrials for Viral Pneumonia

Search NIH Clinical Center for Viral Pneumonia

Search CenterWatch for Viral Pneumonia

Genetic Tests for Viral Pneumonia

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Anatomical Context for Viral Pneumonia

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34MalaCards
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MalaCards organs/tissues related to Viral Pneumonia:

34
Lung, Testes, Endothelial, Kidney, Monocytes

Animal Models for Viral Pneumonia or affiliated genes

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Publications for Viral Pneumonia

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Sources:
53PubMed
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Articles related to Viral Pneumonia:

(show top 50)    (show all 124)
idTitleAuthorsYear
1
Influenza and endemic viral pneumonia. (24094391)
2013
2
Are statins beneficial for viral pneumonia? (23633609)
2013
3
Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia. (23344833)
2013
4
A Patient who Survived Primary Seasonal Influenza Viral Pneumonia: Histologic Findings Obtained via Bronchoscopy. (24334588)
2013
5
Predictors of viral pneumonia: the need for viral testing in all patients hospitalized for nursing home-acquired pneumonia. (23441872)
2013
6
H7N9 viral pneumonia: asymmetric and irregular changes on computed tomography. (24342341)
2013
7
Clinical significance of pleural effusion in the new influenza A (H1N1) viral pneumonia in children and adolescent. (22028096)
2012
8
Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque. (22491448)
2012
9
Role of procalcitonin and C-reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia. (21668682)
2011
10
Viral pneumonia. (21435708)
2011
11
Case of the month #165: Swine-origin influenza A (H1N1) viral pneumonia presenting as crazy-paving on computed tomography: case report and literature review. (20850032)
2010
12
Epidemic viral pneumonia. (20087179)
2010
13
Mycoplasma pneumoniae pneumonia, bacterial pneumonia and viral pneumonia. (21140042)
2010
14
H1N1 pandemic flu found to cause viral pneumonia in severe cases, says WHO. (19843570)
2009
15
Viral pneumonia: epidemiological, clinical, pathophysiological and therapeutic aspects. (19820817)
2009
16
Viral pneumonia in older adults. (16421796)
2006
17
Measurement of complement receptor 1 on neutrophils in bacterial and viral pneumonia. (16433910)
2006
18
Viral pneumonia: coinfection of cytomegalovirus and herpes simplex virus. (15942111)
2005
19
Non-specific host response markers in the differentiation between pneumococcal and viral pneumonia: what is the most accurate combination? (15491381)
2004
20
Comparison of serum biochemical features between SARS and other viral pneumonias]. (15535901)
2004
21
Herpes simplex viral pneumonia after coronary artery bypass grafting. (12723587)
2003
22
8-nitroguanosine formation in viral pneumonia and its implication for pathogenesis. (12522148)
2003
23
Use of a large national database for comparative evaluation of the effect of a bronchiolitis/viral pneumonia clinical care guideline on patient outcome and resource utilization. (12413334)
2002
24
Viral pneumonia as a serious complication of etanercept therapy. (11790076)
2002
25
Plasma endothelin-1 in infants and young children with acute bronchiolitis and viral pneumonia. (12744623)
2002
26
Tumor necrosis factor as a mediator of inflammation in influenza A viral pneumonia. (8559046)
1995
27
Nosocomial viral pneumonia in the intensive care unit. (7768085)
1995
28
Herpes simplex viral pneumonia in the postthoracotomy patient. (7656651)
1995
29
Replication of equid herpesvirus 4 in endothelial cells and synovia of a field case of viral pneumonia and synovitis in a foal. (7769144)
1995
30
Experimental transmission of an apparent viral pneumonia in conventional and gnotobiotic pigs. (8465501)
1993
31
Bronchoalveolar lavage cell analysis in measles viral pneumonia. (8112435)
1993
32
Intratracheal surfactant administration restores gas exchange in experimental adult respiratory distress syndrome associated with viral pneumonia. (1850209)
1991
33
Viral pneumonia in recipients of solid organ transplants. (2160718)
1990
34
Viral pneumonia attenuates adenylate cyclase but not beta-adrenergic receptors in murine lung. (2557784)
1989
35
Amelioration of established Sendai viral pneumonia in the nude mouse using a monoclonal antibody to the virus fusion protein. (2557882)
1989
36
Diagnosis of viral pneumonia. (2840725)
1988
37
The participation of antiviral immune mechanisms in alveolar macrophage dysfunction during viral pneumonia. (6871495)
1983
38
Pulmonary inflammatory responses during viral pneumonia and secondary bacterial infection. (6305835)
1983
39
Necrotising aspergillosis complicating fulminating viral pneumonia. (6992331)
1980
40
Alterations in lung macrophage antimicrobial activity associated with viral pneumonia. (232689)
1979
41
Alterations in lung macrophage immune receptor(s) activity associated with viral pneumonia. (229220)
1979
42
Clinical course, management, and long-term sequelae of respiratory failure due to influenza viral pneumonia. (894855)
1977
43
Severe viral pneumonia in young adults. (776544)
1976
44
Intermittent positive-pressure therapy in treatment of viral pneumonia in a horse. (4609034)
1974
45
The effect of air ions on bacterial and viral pneumonia in mice. (5490693)
1970
46
Possible occurrence of viral pneumonia in indigenous sheep and goats--a morphological study of pneumonic lung lesions. (5815284)
1969
47
Pulmonary calcification in viral pneumonia. (5784985)
1969
48
Influenza viral pneumonia of human beings. (13711552)
1960
49
Viral pneumonia of the mother with hemorrhagic otitis in the fetus. (14405210)
1960
50
Viral pneumonia. (18909867)
1948

Variations for Viral Pneumonia

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Expression for genes affiliated with Viral Pneumonia

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Viral Pneumonia

Search GEO for disease gene expression data for Viral Pneumonia.

Pathways for genes affiliated with Viral Pneumonia

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Sources:
51PathCards, 54QIAGEN, 61Thomson Reuters, 56Reactome, 58SinoBiological, 39NCBI BioSystems Database, 31KEGG, 13EMD Millipore
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Pathways related to Viral Pneumonia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Immune response Alternative complement pathway61
Immune response Lectin Induced complement pathway61
Immune response Classic complement pathway61
9.6CR1, CRP
29.5IL6, CRP
39.3CR1, IL6
49.3CR1, IL6
59.3CRP, ALB
69.0CD3D, CR1, IL6
7
Show member pathways
thioredoxin pathway39
8.7CRP, ALB, IL6

Compounds for genes affiliated with Viral Pneumonia

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Sources:
46Novoseek, 12DrugBank, 30IUPHAR, 52PharmGKB, 25HMDB, 62Tocris Bioscience
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Compounds related to Viral Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 148)
idCompoundScoreTop Affiliating Genes
1alpha-hydroxybutyrate469.7CHKB, SLC17A5, GPT
2lactulose469.6SLC17A5, CRP, GPT
3ezetimibe46 1210.4SLC17A5, CRP, GPT
4bezafibrate46 30 1211.3SLC17A5, CRP, CHKB, GPT
5malondialdehyde469.2GPT, CRP, SLC17A5, CHKB
6gamma globulin469.2CRP, SLC17A5, ALB
7hepaplastin469.2ALB, SLC17A5, GPT
8fluvastatin46 52 30 1212.0IL6, CRP, CHKB, GPT
9sevoflurane52 46 1211.0ALB, GPT, SLC17A5
10fenofibrate46 52 1211.0IL6, CRP, SLC17A5, GPT
11pravastatin46 52 30 25 1213.0CRP, IL6, CHKB, GPT
12pioglitazone30 46 52 1211.9GPT, CRP, IL6, SLC17A5
13isoflurane52 46 1210.9ALB, SLC17A5, GPT
14vitamin b6468.9CRP, SLC17A5, ALB
15phosphorus468.8SLC17A5, ALB, CHKB, GPT
16polyethylene glycol468.8SLC17A5, CRP, CHKB, ALB
17pyridoxal 5-phosphate468.8SLC17A5, ALB, GPT
18vitamin b12468.8ALB, SLC17A5, CRP, GPT
19alpha tocopherol468.8CRP, CHKB, GPT, ALB
20neopterin468.7CHKB, GPT, CRP, SLC17A5, IL6
21atorvastatin46 52 30 25 1212.7CRP, SLC17A5, IL6, GPT, CHKB
22simvastatin46 52 62 30 25 1213.7GPT, CHKB, CRP, IL6, SLC17A5
23thyroxine46 259.7CHKB, ALB, SLC17A5, GPT
24n acetylcysteine468.6CHKB, IL6, CRP, SLC17A5, GPT
25endotoxin468.6CRP, CHKB, SLC17A5, IL6, CR1
26ivig468.6IL6, ALB, CRP, GPT
27tacrolimus46 52 1210.6GPT, SLC17A5, ALB, CHKB
28cyclosporin a46 30 6210.4GPT, SLC17A5, CR1, IL6, CHKB
29urea46 25 1210.3SLC17A5, ALB, LCN1, CHKB, GPT
30vitamin a46 25 1210.3GPT, SLC17A5, LCN1, CRP, ALB
31rosiglitazone30 46 52 25 1212.2ALB, SLC17A5, GPT, CRP, IL6
32potassium46 25 1210.2GPT, LCN1, ALB, SLC17A5, CHKB
33iron46 259.1ALB, CRP, SLC17A5, LCN1, GPT
34hyaluronic acid46 259.1SLC17A5, ALB, LCN1, IL6, GPT
35vitamin d468.0CHKB, CR1, ALB, IL6, GPT
36uric acid46 259.0GPT, CHKB, LCN1, ALB, CRP, SLC17A5
37sodium46 258.9LCN1, ALB, CR1, GPT, SLC17A5
38aspartate467.9ALB, SLC17A5, LCN1, CHKB, GPT, CRP
39rosuvastatin46 52 30 1210.9GPT, CRP, SLC17A5, ALB, IL6, CHKB
40methotrexate52 46 129.9GPT, CHKB, SLC17A5, CRP, IL6, ALB
41fibrinogen467.9SLC17A5, IL6, CRP, ALB, CHKB, GPT
42magnesium46 25 129.6LCN1, CR1, GPT, ALB, SLC17A5
43testosterone46 62 25 1210.6CRP, IL6, CHKB, SLC17A5, ALB
44prednisolone46 30 129.4GPT, IL6, CHKB, ALB, CRP, CR1
45lactate467.4CHKB, GPT, ALB, CRP, SLC17A5, LCN1
46creatinine467.4CHKB, SLC17A5, GPT, IL6, LCN1, ALB
47cholesterol46 30 25 1210.4SLC17A5, ALB, LCN1, IL6, CHKB, GPT
48alanine467.3GPT, LCN1, IL6, CHKB, CRP, SLC17A5
49glucose467.3SLC17A5, ALB, IL6, CRP, CHKB, LCN1
50lipid467.3GPT, SLC17A5, CRP, ALB, LCN1, IL6

GO Terms for genes affiliated with Viral Pneumonia

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17Gene Ontology
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Cellular components related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.1CRP, ALB, LCN1, IL6

Biological processes related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1complement activation, classical pathwayGO:0069589.6CR1, CRP
2negative regulation of lipid storageGO:0108889.5CRP, IL6
3defense response to Gram-positive bacteriumGO:0508309.5CRP, IL6
4acute-phase responseGO:0069539.2CRP, IL6
5retina homeostasisGO:0018959.0LCN1, ALB

Molecular functions related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1pyridoxal phosphate bindingGO:0301709.2ALB, GPT

Products for genes affiliated with Viral Pneumonia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Viral Pneumonia

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet