MCID: VRL005
MIFTS: 42

Viral Pneumonia

Categories: Respiratory diseases, Infectious diseases

Aliases & Classifications for Viral Pneumonia

MalaCards integrated aliases for Viral Pneumonia:

Name: Viral Pneumonia 12 14
Pneumonia, Viral 41 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10533
ICD10 32 J12.9 J12
ICD9CM 34 480 480.9
MeSH 41 D011024
UMLS 69 C0032310

Summaries for Viral Pneumonia

Disease Ontology : 12 A pneumonia described as an inflammatory illness of the lung commonly caused by viruses such as influenza virus, parainfluenza, adenovirus, rhinovirus, herpes simplex virus, respiratory syncytial virus, hantavirus, and cytomegalovirus.

MalaCards based summary : Viral Pneumonia, also known as pneumonia, viral, is related to pneumonia and malaria. An important gene associated with Viral Pneumonia is NSMCE3 (NSE3 Homolog, SMC5-SMC6 Complex Component), and among its related pathways/superpathways are Innate Immune System and Toll-like receptor signaling pathway. The drugs Oseltamivir and Ganciclovir have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and neutrophil.

Wikipedia : 72 Viral pneumonia is a pneumonia caused by a virus. Viruses are one of the two major causes of pneumonia,... more...

Related Diseases for Viral Pneumonia

Diseases in the Pneumonia family:

Viral Pneumonia

Diseases related to Viral Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 136)
# Related Disease Score Top Affiliating Genes
1 pneumonia 32.0 CRP IL6 TLR9
2 malaria 28.4 CR1 CRP IL17A IL6 TLR9
3 influenza 11.3
4 lung disease, immunodeficiency, and chromosome breakage syndrome 10.9
5 cold agglutinin disease 10.4 CRP IL6
6 diabetic foot ulcers 10.4 CRP IL6
7 cryopyrin-associated periodic syndrome 10.4 CRP IL6
8 neutrophilia, hereditary 10.4 CRP IL6
9 acute cholangitis 10.4 CRP IL6
10 cardiogenic shock 10.4 CRP IL6
11 uremic pruritus 10.4 CRP IL6
12 spinal disease 10.4 CRP IL6
13 angina pectoris 10.4 CRP IL6
14 cecal disease 10.4 CRP IL6
15 relapsing polychondritis 10.4 CRP IL6
16 subacute thyroiditis 10.4 CRP IL6
17 intussusception 10.4 CRP IL6
18 louse-borne relapsing fever 10.4 CRP IL6
19 hypersensitivity reaction type iii disease 10.4 CRP IL6
20 multicentric castleman disease 10.4 CRP IL6
21 ischemic heart disease 10.4 CRP IL6
22 mesenteric lymphadenitis 10.4 CRP IL6
23 systolic heart failure 10.4 CRP IL6
24 intermittent explosive disorder 10.4 CRP IL6
25 intermediate coronary syndrome 10.4 CRP IL6
26 prediabetes syndrome 10.4 CRP IL6
27 acute cystitis 10.4 CRP IL6
28 polyarteritis nodosa 10.4 CRP IL6
29 acute pyelonephritis 10.4 CRP IL6
30 apnea, obstructive sleep 10.4 CRP IL6
31 adult-onset still's disease 10.4 CRP IL6
32 viral meningitis 10.4 CRP IL6
33 lymph node disease 10.4 CRP IL6
34 infective endocarditis 10.4 CRP IL6
35 hemorrhagic fever with renal syndrome 10.4 CRP IL6
36 peripheral artery disease 10.3 CRP IL6
37 bladder disease 10.3 CRP IL6
38 intermittent claudication 10.3 CRP IL6
39 proliferative glomerulonephritis 10.3 CR1 IL6
40 pericardial effusion 10.3 CRP IL6
41 leptospirosis 10.3 CRP IL6
42 pericarditis 10.3 CRP IL6
43 transverse myelitis 10.3 IL17A IL6
44 pancreas disease 10.3 CRP IL6
45 radiculopathy 10.3 IL17A IL6
46 sleep disorder 10.3 CRP IL6
47 myelitis 10.3 IL17A IL6
48 stromal keratitis 10.3 IL17A IL6
49 pulmonary disease, chronic obstructive 10.3 CRP IL6
50 joint disorders 10.3 IL17A IL6

Comorbidity relations with Viral Pneumonia via Phenotypic Disease Network (PDN):


Acute Cystitis Bronchitis
Chronic Myocardial Ischemia Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Hypothyroidism Ischemic Heart Disease
Postinflammatory Pulmonary Fibrosis Respiratory Failure

Graphical network of the top 20 diseases related to Viral Pneumonia:



Diseases related to Viral Pneumonia

Symptoms & Phenotypes for Viral Pneumonia

Drugs & Therapeutics for Viral Pneumonia

Drugs for Viral Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 33)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Oseltamivir Approved Phase 4 196618-13-0, 204255-11-8 65028
2
Ganciclovir Approved, Investigational Phase 4 82410-32-0 3454
3 Anti-Bacterial Agents Phase 4
4 Antibiotics, Antitubercular Phase 4
5 Anti-Infective Agents Phase 4
6 Antitubercular Agents Phase 4
7 Antiviral Agents Phase 4
8 Acyclovir Phase 4
9 Ganciclovir triphosphate Phase 4
10 Nucleic Acid Synthesis Inhibitors Phase 4
11
Hydrocortisone Approved, Vet_approved Phase 3 50-23-7 657311 5754
12
Butyric Acid Experimental, Investigational Phase 3 107-92-6 264
13 Anti-Allergic Agents Phase 3
14 Anti-Asthmatic Agents Phase 3
15 Anti-Inflammatory Agents Phase 3
16 Autonomic Agents Phase 3
17 Bronchodilator Agents Phase 3
18 Dermatologic Agents Phase 3
19
Fluticasone Phase 3 80474-14-2, 90566-53-3 22833648 62924
20 Peripheral Nervous System Agents Phase 3
21 Respiratory System Agents Phase 3
22 Cortisol succinate Phase 3
23 Hydrocortisone 17-butyrate 21-propionate Phase 3
24 Hydrocortisone acetate Phase 3
25 Hydrocortisone-17-butyrate Phase 3
26
Azithromycin Approved 83905-01-5 53477736 447043 55185
27
Erythromycin Approved, Investigational, Vet_approved 114-07-8 12560
28
Nitric Oxide Approved 10102-43-9 145068
29 Cephalosporins
30 Erythromycin Estolate
31 Erythromycin Ethylsuccinate
32 Erythromycin stearate
33 Gastrointestinal Agents

Interventional clinical trials:

(show all 16)

# Name Status NCT ID Phase Drugs
1 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
2 Rapid Empiric Treatment With Oseltamivir Study (RETOS) Completed NCT01248715 Phase 4 oseltamivir
3 PTH - Preemptive Treatment for Herpesviridae Recruiting NCT02152358 Phase 4 Aciclovir;Ganciclovir;Placebo
4 Inhaled Corticosteroids in U-5 Children With Acute Respiratory Infection in Uganda: A Randomised Trial Completed NCT01868113 Phase 3 Inhaled corticosteroid
5 Low Doses Corticosteroids as Adjuvant Therapy for the Treatment of Severe H1N1 Flu Terminated NCT01014364 Phase 3 hydrocortisone;isotonic saline
6 Use of TREM-1 Protein to Differentiate Viral and Bacterial Pneumonias in Intubated Children Unknown status NCT00645619
7 A Registry Study on Xiyanping(a Chinese Medicine Injection) Used in Fifty Hospitals Unknown status NCT01612572
8 The Impact of Simultaneous Presence of Viral and Bacterial Pathogens on Therapy and Course of Severe Pneumonia Unknown status NCT02203110
9 Effectiveness Study of Integrative Treatment for Pediatric Community Acquired Pneumonia Unknown status NCT02362906 Xiyanping injection;wind-heat formula granules;phlegm-heat formula granules;Fu-xiong San;second generation cephalosporin;Erythromycin;Azithromycin
10 Severe Pandemic H1N1 Infection in ICU: Comparative Resource Utilization Completed NCT01485237
11 Long-term Outcome and Lung Capacity in Survivors of ARDS Due to Influenza A (H1N1) v2009 The RESPIFLU Study Completed NCT01271842
12 Pneumonia in the Intensive Care Unit (ICU) Setting Recruiting NCT02685930
13 Surveillance of Hospitalised Pneumonia and Bacterial Meningitis in Tône District, Togo, 2010-2013 Recruiting NCT01747369
14 Managing Bacterial Pneumonia in Children Without Antimicrobials Not yet recruiting NCT03256474
15 Clinical Pediatric Pneumonia Score in Critically Ill Children Withdrawn NCT02139384
16 Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For CAP Withdrawn NCT01662258

Search NIH Clinical Center for Viral Pneumonia

Cochrane evidence based reviews: pneumonia, viral

Genetic Tests for Viral Pneumonia

Anatomical Context for Viral Pneumonia

MalaCards organs/tissues related to Viral Pneumonia:

38
Lung, Testes, Neutrophil, Endothelial, Monocytes, Kidney

Publications for Viral Pneumonia

Articles related to Viral Pneumonia:

(show top 50) (show all 156)
# Title Authors Year
1
Application of extracorporeal membrane oxygenation in patients with severe acute respiratory distress syndrome induced by avian influenza A (H7N9) viral pneumonia: national data from the Chinese multicentre collaboration. ( 29310581 )
2018
2
Hemorrhagic encephalitis associated with H3N2 influenza A viral pneumonia. ( 29440541 )
2018
3
Stewardship opportunities in viral pneumonia: why not the immunocompromised? ( 29423923 )
2018
4
Viral Pneumonia in Patients with Hematologic Malignancy or Hematopoietic Stem Cell Transplantation. ( 28159165 )
2017
5
Vaccines in the Prevention of Viral Pneumonia. ( 28159157 )
2017
6
Epidemiology of Viral Pneumonia. ( 28159152 )
2017
7
Emodin Inhibition of Influenza A Virus Replication and Influenza Viral Pneumonia via the Nrf2, TLR4, p38/JNK and NF-kappaB Pathways. ( 29057806 )
2017
8
Viral Pneumonia in Patients with Hematopoietic Cell Transplantation and Hematologic Malignancies. ( 28477640 )
2017
9
Does atopy affect the course of viral pneumonia? ( 28634031 )
2017
10
Secondary organizing pneumonia following viral pneumonia caused by severe influenza B: a case report and literature reviews. ( 28810835 )
2017
11
The impact of pneumococcal vaccination on bacterial and viral pneumonia in Western Australian children: record linkage cohort study of 469,589 births (1996-2012). ( 29069315 )
2017
12
Severe viral pneumonia in adults: what is important for the ICU physician? ( 28633583 )
2017
13
Retrospective review of epidemic viral pneumonia cases in Turkey: A multicenter study. ( 28413489 )
2017
14
Effect of low-to-moderate-dose corticosteroids on mortality of hospitalized adolescents and adults with influenza A(H1N1)pdm09 viral pneumonia. ( 28464462 )
2017
15
Bacterial and viral pneumonia: New insights from the Drakenstein Child Health Study. ( 28687247 )
2017
16
Viral Pneumonia and Acute Respiratory Distress Syndrome. ( 28159154 )
2017
17
Adjuvant Corticosteroid Treatment in Adults With Influenza A (H7N9) Viral Pneumonia. ( 26934144 )
2016
18
Graft Loss and Clad Onset is Hastened by Viral Pneumonia After Lung Transplantation. ( 27467538 )
2016
19
Protective effects of Yinhuapinggan granule on mice with influenza viral pneumonia. ( 26655878 )
2016
20
CAUSATIVE AGENTS OF SEVERE COMMUNITY ACQUIRED VIRAL PNEUMONIA AMONG CHILDREN IN EASTERN THAILAND. ( 26867384 )
2015
21
Impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: an opportunity for stewardship. ( 26577540 )
2015
22
Review of Non-Bacterial Infections in Respiratory Medicine: Viral Pneumonia. ( 25957460 )
2015
23
Epidemiology, Co-Infections, and Outcomes of Viral Pneumonia in Adults: An Observational Cohort Study. ( 26683973 )
2015
24
The Serum Value of NO and IL-17 were Increased in Children with Influenza A Viral Pneumonia. ( 26642702 )
2015
25
Predictors of viral pneumonia in patients with community-acquired pneumonia. ( 25531901 )
2014
26
Epidemiology, etiology, x-ray features, importance of co-infections and clinical features of viral pneumonia in developing countries. ( 24410617 )
2014
27
Combination therapy with hepatocyte growth factor and oseltamivir confers enhanced protection against influenza viral pneumonia. ( 24894172 )
2014
28
Viral pneumonia in severe respiratory failure. ( 24602995 )
2014
29
Middle East respiratory syndrome (MERS): a new zoonotic viral pneumonia. ( 25089913 )
2014
30
Aging exacerbates damage and delays repair of alveolar epithelia following influenza viral pneumonia. ( 25265939 )
2014
31
Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia. ( 23344833 )
2013
32
Effect of the Haoqinqingdan decoction on damp-heat syndrome in rats with influenza viral pneumonia. ( 23790339 )
2013
33
Influenza and endemic viral pneumonia. ( 24094391 )
2013
34
Are statins beneficial for viral pneumonia? ( 23633609 )
2013
35
IgA level in plasma as a differential factor for influenza infection in severe viral pneumonia. ( 24380719 )
2013
36
H7N9 viral pneumonia: asymmetric and irregular changes on computed tomography. ( 24342341 )
2013
37
Gravity-dependent opacity in pure influenza viral pneumonia. ( 23370759 )
2013
38
Predictors of viral pneumonia: the need for viral testing in all patients hospitalized for nursing home-acquired pneumonia. ( 23441872 )
2013
39
A Patient who Survived Primary Seasonal Influenza Viral Pneumonia: Histologic Findings Obtained via Bronchoscopy. ( 24334588 )
2013
40
Clinical significance of pleural effusion in the new influenza A (H1N1) viral pneumonia in children and adolescent. ( 22028096 )
2012
41
Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque. ( 22491448 )
2012
42
Radiological findings in 210 paediatric patients with viral pneumonia: a retrospective case study. ( 22514104 )
2012
43
Comparison of initial high resolution computed tomography features in viral pneumonia between metapneumovirus infection and severe acute respiratory syndrome. ( 21439753 )
2012
44
Alveolar epithelial cells orchestrate DC function in murine viral pneumonia. ( 22996662 )
2012
45
Type I interferon signaling regulates Ly6C(hi) monocytes and neutrophils during acute viral pneumonia in mice. ( 21383977 )
2011
46
Confirmed swine-origin influenza A(H1N1) viral pneumonia: computed tomographic findings in the immunocompetent and the immunocompromised. ( 21926856 )
2011
47
ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia. ( 22072972 )
2011
48
H1N1: viral pneumonia as a cause of acute respiratory distress syndrome. ( 21157318 )
2011
49
Etiology and epidemiology of viral pneumonia among hospitalized children in rural Mozambique: a malaria endemic area with high prevalence of human immunodeficiency virus. ( 20805786 )
2011
50
Clinical characteristics and computed tomography findings in children with 2009 pandemic influenza A (H1N1) viral pneumonia. ( 20854219 )
2011

Variations for Viral Pneumonia

Expression for Viral Pneumonia

Search GEO for disease gene expression data for Viral Pneumonia.

Pathways for Viral Pneumonia

GO Terms for Viral Pneumonia

Biological processes related to Viral Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of interleukin-6 production GO:0032755 9.32 IL6 TLR9
2 acute-phase response GO:0006953 9.26 CRP IL6
3 inflammatory response GO:0006954 9.26 CRP IL17A IL6 TLR9
4 positive regulation of chemokine production GO:0032722 9.16 IL6 TLR9
5 negative regulation of lipid storage GO:0010888 8.62 CRP IL6

Sources for Viral Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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