MCID: VRL005
MIFTS: 47

Viral Pneumonia malady

Respiratory diseases category
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Summaries for Viral Pneumonia

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Disease Ontology:8 A pneumonia described as an inflammatory illness of the lung commonly caused by viruses such as influenza virus, parainfluenza, adenovirus, rhinovirus, herpes simplex virus, respiratory syncytial virus, hantavirus, and cytomegalovirus.

MalaCards based summary: Viral Pneumonia, also known as pneumonia, viral, is related to pneumonia and vascular disease. An important gene associated with Viral Pneumonia is FCRL6 (Fc receptor-like 6), and among its related pathways are Complement Pathway and IL6-mediated signaling events. The compounds alpha-hydroxybutyrate and lactulose have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and endothelial.

Wikipedia:65 Viral pneumonia is a pneumonia caused by a virus. Viruses are one of the two major causes of pneumonia,... more...

Aliases & Classifications for Viral Pneumonia

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Viral Pneumonia, Aliases & Descriptions:

Name: Viral Pneumonia 8 10
 
Pneumonia, Viral 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


External Ids:

Disease Ontology8 DOID:10533
MeSH34 D011024
ICD9CM27 480, 480.9
ICD1025 J12

Related Diseases for Viral Pneumonia

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Diseases in the Pneumonia family:

viral pneumonia

Diseases related to Viral Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 109)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia31.2IL6, CR1, CRP, FCRL6
2vascular disease30.5IL6
3viral meningitis30.5CRP, IL6
4respiratory failure30.4CRP, IL6
5malaria30.3ALB, CR1
6adult respiratory distress syndrome30.0CR1, IL6
7synovitis29.7CRP, IL6
8sepsis29.5CR1, IL6, ALB, CRP
9influenza10.7
10bacteriuria10.5CRP
11cardiac rupture10.5CHKB
12neuroleptic malignant syndrome10.5CHKB
13pericardial effusion10.5CHKB
14pyelonephritis10.5CRP
15aortic aneurysm10.5CRP
16cholecystitis10.4GPT
17herpes simplex10.4
18fatty liver disease10.4CRP
19crohn's disease10.3CRP, ALB
20choledocholithiasis10.3GPT, SLC17A5
21scrub typhus10.3SLC17A5, GPT
22pyridoxine deficiency10.3GPT, SLC17A5
23obstructive jaundice10.2SLC17A5, GPT
24kawasaki disease10.2CRP, GPT
25hellp syndrome10.2GPT, SLC17A5
26alcohol abuse10.2GPT, SLC17A5
27splenomegaly10.2SLC17A5, GPT
28wilson disease10.2SLC17A5, GPT
2921-hydroxylase deficiency10.2SLC17A5, GPT
30bacterial meningitis10.2CRP, CR1
31reactive arthritis10.2CR1, CRP
32ulcerative colitis10.2ALB, CRP
33bronchiolitis10.2
34measles10.2
35endotheliitis10.2
36autoimmune hepatitis10.2SLC17A5, GPT
37metabolic acidosis10.2ALB, CHKB
38membranous glomerulonephritis10.1CR1, ALB
39hyperhomocysteinemia10.1ALB, CRP
40viral hepatitis10.1GPT, SLC17A5
41adult-onset still's disease10.1IL6, CRP
42myositis10.1CHKB, SLC17A5
43chorioamnionitis10.1IL6, CRP
44chronic obstructive pulmonary disease10.1IL6, CRP
45spiradenoma10.1CRP, IL6
46juvenile rheumatoid arthritis10.1IL6, CRP
47lupus nephritis10.1ALB, CR1
48familial hyperlipidemia10.1GPT, CRP, SLC17A5
49periodontal disease10.1CRP, IL6
50acute kidney failure10.1GPT, CHKB, ALB

Graphical network of the top 20 diseases related to Viral Pneumonia:



Diseases related to viral pneumonia

Symptoms for Viral Pneumonia

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Drugs & Therapeutics for Viral Pneumonia

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Drug clinical trials:

Search ClinicalTrials for Viral Pneumonia

Search NIH Clinical Center for Viral Pneumonia

Genetic Tests for Viral Pneumonia

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Anatomical Context for Viral Pneumonia

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MalaCards organs/tissues related to Viral Pneumonia:

32
Lung, Testes, Endothelial, Neutrophil, Kidney, Monocytes

Animal Models for Viral Pneumonia or affiliated genes

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Publications for Viral Pneumonia

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Articles related to Viral Pneumonia:

(show top 50)    (show all 130)
idTitleAuthorsYear
1
Viral pneumonia in severe respiratory failure. (24602995)
2014
2
Influenza and endemic viral pneumonia. (24094391)
2013
3
Are statins beneficial for viral pneumonia? (23633609)
2013
4
Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia. (23344833)
2013
5
A Patient who Survived Primary Seasonal Influenza Viral Pneumonia: Histologic Findings Obtained via Bronchoscopy. (24334588)
2013
6
Predictors of viral pneumonia: the need for viral testing in all patients hospitalized for nursing home-acquired pneumonia. (23441872)
2013
7
Clinical significance of pleural effusion in the new influenza A (H1N1) viral pneumonia in children and adolescent. (22028096)
2012
8
Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-induced viral pneumonia in the rhesus macaque. (22491448)
2012
9
Role of procalcitonin and C-reactive protein in differentiation of mixed bacterial infection from 2009 H1N1 viral pneumonia. (21668682)
2011
10
Viral pneumonia. (21435708)
2011
11
Case of the month #165: Swine-origin influenza A (H1N1) viral pneumonia presenting as crazy-paving on computed tomography: case report and literature review. (20850032)
2010
12
Epidemic viral pneumonia. (20087179)
2010
13
Mycoplasma pneumoniae pneumonia, bacterial pneumonia and viral pneumonia. (21140042)
2010
14
H1N1 pandemic flu found to cause viral pneumonia in severe cases, says WHO. (19843570)
2009
15
Viral pneumonia: epidemiological, clinical, pathophysiological and therapeutic aspects. (19820817)
2009
16
Viral pneumonia in older adults. (16421796)
2006
17
Measurement of complement receptor 1 on neutrophils in bacterial and viral pneumonia. (16433910)
2006
18
Viral pneumonia: coinfection of cytomegalovirus and herpes simplex virus. (15942111)
2005
19
Non-specific host response markers in the differentiation between pneumococcal and viral pneumonia: what is the most accurate combination? (15491381)
2004
20
Comparison of serum biochemical features between SARS and other viral pneumonias]. (15535901)
2004
21
Herpes simplex viral pneumonia after coronary artery bypass grafting. (12723587)
2003
22
8-nitroguanosine formation in viral pneumonia and its implication for pathogenesis. (12522148)
2003
23
Use of a large national database for comparative evaluation of the effect of a bronchiolitis/viral pneumonia clinical care guideline on patient outcome and resource utilization. (12413334)
2002
24
Viral pneumonia as a serious complication of etanercept therapy. (11790076)
2002
25
Plasma endothelin-1 in infants and young children with acute bronchiolitis and viral pneumonia. (12744623)
2002
26
Tumor necrosis factor as a mediator of inflammation in influenza A viral pneumonia. (8559046)
1995
27
Nosocomial viral pneumonia in the intensive care unit. (7768085)
1995
28
Herpes simplex viral pneumonia in the postthoracotomy patient. (7656651)
1995
29
Replication of equid herpesvirus 4 in endothelial cells and synovia of a field case of viral pneumonia and synovitis in a foal. (7769144)
1995
30
Experimental transmission of an apparent viral pneumonia in conventional and gnotobiotic pigs. (8465501)
1993
31
Bronchoalveolar lavage cell analysis in measles viral pneumonia. (8112435)
1993
32
Intratracheal surfactant administration restores gas exchange in experimental adult respiratory distress syndrome associated with viral pneumonia. (1850209)
1991
33
Viral pneumonia in recipients of solid organ transplants. (2160718)
1990
34
Viral pneumonia attenuates adenylate cyclase but not beta-adrenergic receptors in murine lung. (2557784)
1989
35
Amelioration of established Sendai viral pneumonia in the nude mouse using a monoclonal antibody to the virus fusion protein. (2557882)
1989
36
Diagnosis of viral pneumonia. (2840725)
1988
37
The participation of antiviral immune mechanisms in alveolar macrophage dysfunction during viral pneumonia. (6871495)
1983
38
Pulmonary inflammatory responses during viral pneumonia and secondary bacterial infection. (6305835)
1983
39
Necrotising aspergillosis complicating fulminating viral pneumonia. (6992331)
1980
40
Alterations in lung macrophage antimicrobial activity associated with viral pneumonia. (232689)
1979
41
Alterations in lung macrophage immune receptor(s) activity associated with viral pneumonia. (229220)
1979
42
Clinical course, management, and long-term sequelae of respiratory failure due to influenza viral pneumonia. (894855)
1977
43
Severe viral pneumonia in young adults. (776544)
1976
44
Intermittent positive-pressure therapy in treatment of viral pneumonia in a horse. (4609034)
1974
45
Fatal influenza A2 viral pneumonia in a newborn infant. (4759372)
1973
46
The effect of air ions on bacterial and viral pneumonia in mice. (5490693)
1970
47
Possible occurrence of viral pneumonia in indigenous sheep and goats--a morphological study of pneumonic lung lesions. (5815284)
1969
48
Influenza viral pneumonia of human beings. (13711552)
1960
49
Viral pneumonia of the mother with hemorrhagic otitis in the fetus. (14405210)
1960
50
Viral pneumonia. (18909867)
1948

Variations for Viral Pneumonia

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Expression for genes affiliated with Viral Pneumonia

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Expression patterns in normal tissues for genes affiliated with Viral Pneumonia

Search GEO for disease gene expression data for Viral Pneumonia.

Pathways for genes affiliated with Viral Pneumonia

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Pathways related to Viral Pneumonia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Immune response Alternative complement pathway60
Immune response Lectin Induced complement pathway60
Immune response Classic complement pathway60
9.6CRP, CR1
29.5IL6, CRP
39.3CR1, IL6
49.3IL6, CR1
59.3ALB, CRP
69.0CD3D, CR1, IL6
7
Show member pathways
thioredoxin pathway37
8.7IL6, ALB, CRP

Compounds for genes affiliated with Viral Pneumonia

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Compounds related to Viral Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 148)
idCompoundScoreTop Affiliating Genes
1alpha-hydroxybutyrate449.7CHKB, SLC17A5, GPT
2lactulose449.6SLC17A5, CRP, GPT
3ezetimibe44 1110.4SLC17A5, CRP, GPT
4bezafibrate44 28 1111.3SLC17A5, CRP, CHKB, GPT
5malondialdehyde449.2GPT, CRP, SLC17A5, CHKB
6gamma globulin449.2CRP, SLC17A5, ALB
7hepaplastin449.2ALB, SLC17A5, GPT
8fluvastatin44 50 28 1112.0IL6, CRP, CHKB, GPT
9sevoflurane50 44 1111.0ALB, GPT, SLC17A5
10fenofibrate44 50 1111.0IL6, CRP, SLC17A5, GPT
11pravastatin44 50 28 24 1113.0CRP, IL6, CHKB, GPT
12pioglitazone28 44 50 1111.9GPT, CRP, IL6, SLC17A5
13isoflurane50 44 1110.9ALB, SLC17A5, GPT
14vitamin b6448.9CRP, SLC17A5, ALB
15phosphorus448.8SLC17A5, ALB, CHKB, GPT
16polyethylene glycol448.8SLC17A5, CRP, CHKB, ALB
17pyridoxal 5-phosphate448.8SLC17A5, ALB, GPT
18vitamin b12448.8ALB, SLC17A5, CRP, GPT
19alpha tocopherol448.8CRP, CHKB, GPT, ALB
20neopterin448.7CHKB, GPT, CRP, SLC17A5, IL6
21atorvastatin44 50 28 24 1112.7CRP, SLC17A5, IL6, GPT, CHKB
22simvastatin44 50 61 28 24 1113.7GPT, CHKB, CRP, IL6, SLC17A5
23thyroxine44 249.7CHKB, ALB, SLC17A5, GPT
24n acetylcysteine448.6CHKB, IL6, CRP, SLC17A5, GPT
25endotoxin448.6CRP, CHKB, SLC17A5, IL6, CR1
26ivig448.6IL6, ALB, CRP, GPT
27tacrolimus44 50 1110.6GPT, SLC17A5, ALB, CHKB
28cyclosporin a44 28 6110.4GPT, SLC17A5, CR1, IL6, CHKB
29urea44 24 1110.3SLC17A5, ALB, LCN1, CHKB, GPT
30vitamin a44 24 1110.3GPT, SLC17A5, LCN1, CRP, ALB
31rosiglitazone28 44 50 24 1112.2ALB, SLC17A5, GPT, CRP, IL6
32potassium44 24 1110.2GPT, LCN1, ALB, SLC17A5, CHKB
33iron44 249.1ALB, CRP, SLC17A5, LCN1, GPT
34hyaluronic acid44 249.1SLC17A5, ALB, LCN1, IL6, GPT
35vitamin d448.0CHKB, CR1, ALB, IL6, GPT
36uric acid44 249.0GPT, CHKB, LCN1, ALB, CRP, SLC17A5
37sodium44 248.9LCN1, ALB, CR1, GPT, SLC17A5
38aspartate447.9ALB, SLC17A5, LCN1, CHKB, GPT, CRP
39rosuvastatin44 50 28 1110.9GPT, CRP, SLC17A5, ALB, IL6, CHKB
40methotrexate50 44 119.9GPT, CHKB, SLC17A5, CRP, IL6, ALB
41fibrinogen447.9SLC17A5, IL6, CRP, ALB, CHKB, GPT
42magnesium44 24 119.6LCN1, CR1, GPT, ALB, SLC17A5
43testosterone44 61 24 1110.6CRP, IL6, CHKB, SLC17A5, ALB
44prednisolone44 28 119.4GPT, IL6, CHKB, ALB, CRP, CR1
45lactate447.4CHKB, GPT, ALB, CRP, SLC17A5, LCN1
46creatinine447.4CHKB, SLC17A5, GPT, IL6, LCN1, ALB
47cholesterol44 28 24 1110.4SLC17A5, ALB, LCN1, IL6, CHKB, GPT
48alanine447.3GPT, LCN1, IL6, CHKB, CRP, SLC17A5
49glucose447.3SLC17A5, ALB, IL6, CRP, CHKB, LCN1
50lipid447.3GPT, SLC17A5, CRP, ALB, LCN1, IL6

GO Terms for genes affiliated with Viral Pneumonia

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Cellular components related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.1CRP, ALB, LCN1, IL6

Biological processes related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1complement activation, classical pathwayGO:0069589.6CR1, CRP
2negative regulation of lipid storageGO:0108889.5IL6, CRP
3defense response to Gram-positive bacteriumGO:0508309.5IL6, CRP
4acute-phase responseGO:0069539.2IL6, CRP
5retina homeostasisGO:0018959.0ALB, LCN1

Molecular functions related to Viral Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1pyridoxal phosphate bindingGO:0301709.2ALB, GPT

Products for genes affiliated with Viral Pneumonia

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  • Antibodies
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Sources for Viral Pneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet