MCID: VTM002
MIFTS: 45

Vitamin B12 Deficiency malady

Categories: Metabolic diseases

Aliases & Classifications for Vitamin B12 Deficiency

Aliases & Descriptions for Vitamin B12 Deficiency:

Name: Vitamin B12 Deficiency 12 52 14
Cobalamin Deficiency 12 29
Vitamin B 12 Deficiency 69
Hypocobalaminemia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050731

Summaries for Vitamin B12 Deficiency

Disease Ontology : 12 A vitamin metabolic disorder that results from low blood levels of vitamin B12.

MalaCards based summary : Vitamin B12 Deficiency, also known as cobalamin deficiency, is related to megaloblastic anemia and congenital intrinsic factor deficiency. An important gene associated with Vitamin B12 Deficiency is MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase), and among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and Carbon metabolism. The drugs Hydroxocobalamin and Iron have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and testes, and related phenotype is Increased shRNA abundance.

Related Diseases for Vitamin B12 Deficiency

Diseases related to Vitamin B12 Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
id Related Disease Score Top Affiliating Genes
1 megaloblastic anemia 32.3 GPT TCN2
2 congenital intrinsic factor deficiency 29.9 ACADVL ADAM17 CD79A EPO GIF GPT
3 poems syndrome 29.8 EPO GIF TF
4 transcobalamin ii deficiency 11.4
5 megaloblastic anemia-1, finnish type 11.4
6 atrophic gastritis 11.3
7 autoimmune atrophic gastritis 11.0
8 diphyllobothriasis 11.0
9 blind loop syndrome 11.0
10 pernicious anemia 10.9
11 neuropathy 10.4
12 myh7-related myosin storage myopathy 10.3 MTHFR MTR
13 homocystinuria due to mthfr deficiency 10.3 MTHFR MTR
14 deafness, autosomal recessive 45 10.3 MTHFR MTR
15 warburg micro syndrome 3 10.3 MTHFR MTR
16 houlston ironton temple syndrome 10.3 MTHFR MTR
17 cdkn2a-related cutaneous malignant melanoma 10.2 MTR TCN2
18 whipple disease 10.2 MTHFR TF
19 purulent endophthalmitis 10.2 CD79A MTR
20 amyotrophic lateral sclerosis type 10 10.2 CD79A GIF
21 autosomal dominant sideroblastic anemia 10.2 MTHFR MTR
22 dementia 10.2
23 calcaneonavicular coalition 10.2 MTR TCN2
24 male genital organ stricture 10.2 CD79A TF
25 pancytopenia 10.2
26 hyperhomocysteinemia 10.2
27 coronary artery dissection, spontaneous 10.2 CD79A TF
28 akinetopsia 10.2 CD79A GIF
29 tmem216-related meckel syndrome 10.2 EPO TF
30 atrial fibrillation, familial, 4 10.2 ACADVL MTHFR
31 cerebral sarcoidosis 10.1 EPO TF
32 myosclerosis, congenital 10.1 MTHFR MTR TCN2
33 hyperekplexia 2, autosomal recessive 10.1 MTHFR MTR TCN2
34 post-thrombotic syndrome 10.1 EPO TF
35 malignant hyperthermia susceptibility 1 10.1 CD79A TF
36 adenosine triphosphate, elevated, of erythrocytes 10.1 EPO MTHFR
37 cleft lip 10.1 MTHFR MTR TCN2
38 female infertility of uterine origin 10.1 GPT TF
39 somatostatinoma 10.1 CD79A GIF
40 rhabdomyosarcoma 10.1 MTR TCN2
41 central nervous system origin vertigo 10.1 CD79A TF
42 deficiency anemia 10.1
43 spinal cord lipoma 10.1 ADAM17 MTHFR
44 spastic entropion 10.0 CD79A TF
45 hnrnpa1-related amyotrophic lateral sclerosis 10.0 MTHFR TCN2
46 color blindness 10.0 GIF TCN1 TCN2
47 sennetsu fever 10.0 GPT TCN2
48 familial nephrotic syndrome 10.0 CD79A EPO TF
49 calcinosis 10.0 CD79A EPO TF
50 membranoproliferative glomerulonephritis 10.0 CD79A EPO TF

Graphical network of the top 20 diseases related to Vitamin B12 Deficiency:



Diseases related to Vitamin B12 Deficiency

Symptoms & Phenotypes for Vitamin B12 Deficiency

GenomeRNAi Phenotypes related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance GR00327-A 8.92 CD79A EPO MTHFR MTR

Drugs & Therapeutics for Vitamin B12 Deficiency

Drugs for Vitamin B12 Deficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 237)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydroxocobalamin Approved Phase 4,Phase 2,Phase 3 13422-51-0 11953898 5460373 44475014
2
Iron Approved Phase 4,Phase 2,Phase 3 7439-89-6 23925
3
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
4
Copper Approved Phase 4,Phase 3,Phase 2 15158-11-9, 7440-50-8 27099
5
Zinc Approved Phase 4,Phase 3 7440-66-6 32051 23994
6
Selenium Approved, Vet_approved Phase 4,Phase 3 7782-49-2
7
Cyanocobalamin Approved, Nutraceutical Phase 4,Phase 2,Phase 3 68-19-9 44176380
8
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 59-30-3 6037
9
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 11103-57-4, 68-26-8 445354
10
Thiamine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 59-43-8 1130
11
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 50-14-6 5280793
12
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-02-9 14985
13
leucovorin Approved, Nutraceutical Phase 4,Phase 2,Phase 3 58-05-9 54575, 6560146 143
14
Niacin Approved, Investigational, Nutraceutical Phase 4,Phase 3,Phase 2 59-67-6 938
15
Nicotinamide Approved, Nutraceutical Phase 4,Phase 3,Phase 2 98-92-0 936
16
Pyridoxal Approved, Nutraceutical Phase 4,Phase 3,Phase 2 66-72-8 1050
17
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 65-23-6 1054
18
Riboflavin Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 83-88-5 493570
19
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Phase 2 50-81-7 5785 54670067
20
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1 67-97-0 6221 10883523 5280795
21 Hematinics Phase 4,Phase 2,Phase 3
22 Micronutrients Phase 4,Phase 3,Phase 2,Phase 1
23 Retinol palmitate Phase 4,Phase 3,Phase 2
24 Trace Elements Phase 4,Phase 3,Phase 2,Phase 1
25 Vitamin B 12 Phase 4,Phase 2,Phase 3
26 Vitamin B Complex Phase 4,Phase 2,Phase 3,Phase 1
27 Vitamins Phase 4,Phase 3,Phase 2,Phase 1
28 Antacids Phase 4,Phase 2,Phase 3
29 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3
30 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
31
Proton pump inhibitors Phase 4
32 Bone Density Conservation Agents Phase 4,Phase 2,Phase 3,Phase 1
33 Calcifediol Phase 4 19356-17-3
34 Ergocalciferols Phase 4,Phase 3,Phase 2,Phase 1
35 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2
36 vitamin d Phase 4,Phase 2,Phase 3,Phase 1
37 Antioxidants Phase 4,Phase 3,Phase 2
38 Protective Agents Phase 4,Phase 3,Phase 2
39 Tocopherols Phase 4,Phase 3,Phase 2
40 Tocotrienols Phase 4,Phase 3,Phase 2
41 Antimetabolites Phase 4,Phase 3,Phase 2
42 Dermatologic Agents Phase 4,Phase 3,Phase 2
43 Hypolipidemic Agents Phase 4,Phase 3
44
Iodine Phase 4,Phase 3,Phase 2 7553-56-2 807
45 Lipid Regulating Agents Phase 4,Phase 3
46 Nicotinic Acids Phase 4,Phase 3,Phase 2
47 Photosensitizing Agents Phase 4,Phase 3
48 Vitamin B 6 Phase 4,Phase 3,Phase 2
49 cadexomer iodine Phase 4,Phase 3,Phase 2
50 Vasodilator Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 175)
id Name Status NCT ID Phase
1 Vitamin Deficiencies and Suppletion in Morbid Obesity Unknown status NCT02270749 Phase 4
2 How Many Patients Are in Need of Vitamin B12 Injections? Unknown status NCT00326833 Phase 4
3 Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC Unknown status NCT01795794 Phase 4
4 Prevention of Renal Complications of Diabetes With Thiamine Unknown status NCT01725412 Phase 4
5 Value Antiproteinuric Effects From Vitamin D Derivatives in Patient With Chronic Kidney Illness and the Lack of Vitamin D Unknown status NCT01442272 Phase 4
6 The Role of Methycobalamin in Early Dementia Patients With Vitamin B12 Deficiency and Hyperhomocysteinaemia. Completed NCT00165711 Phase 4
7 Vitamin B12 Acceptance and Biomarker Response Study Completed NCT01832129 Phase 4
8 Vitamin B12 Supplement to Prevent Cognitive Decline Completed NCT02457507 Phase 4
9 Postoperative Vitamin Supplementation in Morbidly Obese Patient (VITAAL Study) Completed NCT01609387 Phase 4
10 Effect of Prenatal Nutritional Supplementation on Birth Outcome in Hounde District, Burkina Faso Completed NCT00909974 Phase 4
11 Effectiveness of Selling Micronutrient Sprinkles in Rural Kenya Completed NCT01088958 Phase 4
12 Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso Completed NCT00642408 Phase 4
13 Iodine Status of Preschoolers Given Micronutrient Powder for 6 Months Completed NCT02280330 Phase 4
14 Effect of Folic Acid Supplementation on Plasma Homocysteine Level in Obese Children Completed NCT01766310 Phase 4
15 Vitamin Deficiency in Immigrants, a Treatment Study Completed NCT01419119 Phase 4
16 Impact of Preoperative Treatment of Anemia and Iron Deficiency in Cardiac Surgery on Outcome. Recruiting NCT02031289 Phase 4
17 FLIPS: Ferfer Liposomal Iron Performance Study Not yet recruiting NCT03112187 Phase 4
18 Long-term Impact and Intervention for Diarrhea in Brazil Unknown status NCT00133406 Phase 3
19 Vitamin B12 Supplementation During Pregnancy Completed NCT01795131 Phase 2, Phase 3
20 Study of Pylopass Versus Placebo in Subjects Who Are Helicobacter Pylori Carriers and With Mild Indigestion Completed NCT02051348 Phase 2, Phase 3
21 Efficacy of a Novel Multivitamin-Mineral Supplement in Preventing Vitamin Deficiency in Postoperative Bariatric Patients Completed NCT01475617 Phase 2, Phase 3
22 WENBIT - Western Norway B Vitamin Intervention Trial Completed NCT00354081 Phase 3
23 Maintenance of Multivitamin Supplements After Sleeve Gastrectomy Completed NCT02620137 Phase 3
24 Trace Element Replenishment Study in Hemodialysis Patients Completed NCT01473914 Phase 3
25 Effects of Low-dose Complex B-vitamins on Homocysteine and Framingham Risk Score Among Chinese Elderly Completed NCT00755664 Phase 3
26 Prevention of Recurrent Aphthous Stomatitis Using Vitamins Completed NCT00527306 Phase 3
27 Antenatal Micronutrient Supplementation and Infant Survival Completed NCT00860470 Phase 3
28 A Prospective, Multi-center Study to Evaluate the Efficacy and Safety of Vitamin D3 B.O.N. Intramuscular Injection in Adults With Vitamin D Deficiency Completed NCT02443246 Phase 3
29 Efficacy Trial to Examine Efficacy of Multimicronutrient Home Supplementation in Infants Completed NCT00276198 Phase 3
30 Trial of Vitamins Among Children of HIV-infected Women Completed NCT00197730 Phase 3
31 A Trial of Vitamins and HAART in HIV Disease Progression Completed NCT00383669 Phase 3
32 A Study in Patients With Amyotrophic Lateral Sclerosis (ALS) Completed NCT00444613 Phase 2, Phase 3
33 Trial of Vitamins in HIV Progression and Transmission Completed NCT00197743 Phase 3
34 The Effects of 8-week Choline, Betaine, and Folic Acid Supplementation on Plasma Homocysteine Concentration During Guanidinoacetic Acid Loading in Young Healthy Volunteers Completed NCT01371357 Phase 3
35 Effectiveness of Iron-Fortified Milk on Iron Status and Anemia in Young Children in Mexico Completed NCT00508131 Phase 3
36 Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome Completed NCT00294593 Phase 2, Phase 3
37 Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh Completed NCT00198822 Phase 3
38 Impact of an Amino Acid Composition With Micronutrients on Wellbeing of Patients With Chronic Exhaustion Conditions Completed NCT02997137 Phase 3
39 Vitamin B12 Supplementation During Pregnancy on Cognitive Development Recruiting NCT03071666 Phase 2, Phase 3
40 Vitamin B12, Neurodevelopment and Growth in Nepal Active, not recruiting NCT02272842 Phase 2, Phase 3
41 Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes Active, not recruiting NCT01665378 Phase 3
42 Low-dose Iron Supplementation and Markers of Iron Status Among Non-anemic, Iron-deficient Women Active, not recruiting NCT02683369 Phase 2, Phase 3
43 Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer Active, not recruiting NCT00217737 Phase 3
44 Vitamin D in the Treatment of Primary Restless Legs Syndrome Not yet recruiting NCT02256215 Phase 2, Phase 3
45 Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair or Microsatellite Instability Not yet recruiting NCT02912559 Phase 3
46 Vitamin B12 Status and Response to Vitamin B12 Supplementation in Patients With Parkinson's Disease Terminated NCT00208611 Phase 2, Phase 3
47 Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy Completed NCT00699478 Phase 2
48 Can Recombinant Human Intrinsic Factor Be Used for Evaluation of the Vitamin B12 Absorption? Completed NCT00279552 Phase 2
49 EPI-743 in Cobalamin C Defect: Effects on Visual and Neurological Impairment Completed NCT01793090 Phase 2
50 Vitamin D and Cardiac Autonomic Tone in Hemodialysis Completed NCT01774812 Phase 2

Search NIH Clinical Center for Vitamin B12 Deficiency

Genetic Tests for Vitamin B12 Deficiency

Genetic tests related to Vitamin B12 Deficiency:

id Genetic test Affiliating Genes
1 Cobalamin Deficiency 29

Anatomical Context for Vitamin B12 Deficiency

MalaCards organs/tissues related to Vitamin B12 Deficiency:

39
Spinal Cord, Bone, Testes, Breast, Skin, Brain, Heart

Publications for Vitamin B12 Deficiency

Articles related to Vitamin B12 Deficiency:

(show top 50) (show all 619)
id Title Authors Year
1
Pseudo-Foster Kennedy Syndrome as a Rare Presentation of Vitamin B12 Deficiency. ( 27621919 )
2016
2
Nitrous oxide misuse and vitamin B12 deficiency. ( 27247211 )
2016
3
Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency. ( 27446930 )
2016
4
Reversible Facial Hyperpigmentation Associated With Vitamin B12 Deficiency. ( 27702910 )
2016
5
Prevalence of vitamin B12 deficiency in type 2 diabetic patients using metformin: a cross-sectional study. ( 27276084 )
2016
6
Delayed auditory conduction in diabetes: is metformin-induced vitamin B12 deficiency responsible? ( 27358222 )
2016
7
Study of Vitamin B12 deficiency and peripheral neuropathy in metformin-treated early Type 2 diabetes mellitus. ( 27730072 )
2016
8
Profound Vitamin B12 Deficiency in a 1-Year-Old Child in Botswana: A Call to Initiate Early Empiric Therapy. ( 27306229 )
2016
9
Erratum: Study of Vitamin B12 deficiency and peripheral neuropathy in metformin-treated early Type 2 diabetes mellitus. ( 27867908 )
2016
10
Zotepine-associated vitamin B12 deficiency and pancytopenia. ( 27872328 )
2016
11
Study of correlation between vitamin B12 deficiency and clinical, haematological and electrophysiological parameters. ( 27728753 )
2016
12
Vitamin B12 Deficiency Presenting with Neurological Dysfunction in an Adolescent. ( 27473652 )
2016
13
Association of Vitamin B12 Deficiency and Use of Reverse Osmosis Processed Water for Drinking: A Cross-Sectional Study from Western India. ( 27437269 )
2016
14
Mathematical Modeling of Glutathione Status in Type 2 Diabetics with Vitamin B12 Deficiency. ( 27047940 )
2016
15
Chronic diarrhea in a patient with severe vitamin B12 deficiency: a rare clinical manifestation. ( 26794081 )
2016
16
Holotranscobalamin (HoloTC, Active-B12) and Herbert's model for the development of vitamin B12 deficiency: a review and alternative hypothesis. ( 27350907 )
2016
17
Vitamin B12 deficiency results in severe oxidative stress, leading to memory retention impairment in Caenorhabditis elegans. ( 27840283 )
2016
18
Reticulate pigmentation associated with vitamin B12 deficiency. ( 27294067 )
2016
19
Metformin and Vitamin B12 Deficiency: Where Do We Stand? ( 27806244 )
2016
20
Vitamin B12 Deficiency Across Three Generations Adversely Influences Long-chain Polyunsaturated Fatty Acid Status and Cardiometabolic Markers in Rats. ( 27986122 )
2016
21
Vitamin B12 deficiency in metformin-treated type-2 diabetes patients, prevalence and association with peripheral neuropathy. ( 27716423 )
2016
22
Reference interval of methylmalonic acid concentrations in dried blood spots of healthy, term newborns to facilitate neonatal screening of vitamin B12 deficiency. ( 27040901 )
2016
23
Can vitamin B12 deficiency manifest with acute posterolateral or posterior cord syndrome? ( 28053750 )
2016
24
Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal Hemoglobin. ( 28070432 )
2016
25
Diabetes: Metformin linked to vitamin B12 deficiency. ( 26965381 )
2016
26
Is Metformin-Induced Vitamin B12 Deficiency Responsible for Cognitive Decline in Type 2 Diabetes? ( 27570337 )
2016
27
Maternal vitamin B12 deficiency and abnormal cell-free DNA results in pregnancy. ( 27328203 )
2016
28
Drug-Induced Vitamin B12 Deficiency: A Focus on Proton Pump Inhibitors and Histamine-2 Antagonists. ( 27520327 )
2016
29
Evaluation of Reticulocyte Parameters in Iron Deficiency, Vitamin B12 Deficiency and Mixed Anemia. ( 27156322 )
2016
30
A observational study in patients of diabetes using metformin causing vitamin B12 deficiency causing peripheral neuropathy. ( 27728101 )
2016
31
A case of vitamin B12 deficiency with involuntary movements and bilateral basal ganglia lesions. ( 27356735 )
2016
32
Functional vitamin B12 deficiency in advanced malignancy: implications for the management of neuropathy and neuropathic pain. ( 27003903 )
2016
33
When the picture is fragmented: Vitamin B12 deficiency masquerading as thrombotic thrombocytopenic purpura. ( 27308258 )
2016
34
Effect of vitamin B12 deficiency on olfactory function. ( 27119316 )
2016
35
Prevalence of vitamin B12 deficiency in type 2 diabetic patients using metformin: a cross-sectional study. ( 28076635 )
2016
36
Vitamin B12 Deficiency in Infancy: The Case for Screening. ( 26806811 )
2016
37
Pseudo-Thrombotic Thrombocytopenic Purpura due to Severe Vitamin B12 Deficiency. ( 28045688 )
2016
38
Vitamin B12 Deficiency Induced by the Use of Gastric Acid Inhibitors: Calcium Supplements as a Potential Effect Modifier. ( 27102797 )
2016
39
Oxidative Stress Markers in Vitamin B12 Deficiency. ( 26843105 )
2016
40
Toe pseudoathetosis in vitamin B12 deficiency. ( 27079552 )
2016
41
Vitamin B12 deficiency is associated with cardiovascular autonomic neuropathy in patients with type 2 diabetes. ( 27638143 )
2016
42
Experimental vitamin B12 deficiency in a human subject: a longitudinal investigation of the performance of the holotranscobalamin (HoloTC, Active-B12) immunoassay. ( 27026880 )
2016
43
Reversible ecchymosis and hyperpigmented lesions: A rare presentation of dietary Vitamin B12 deficiency. ( 27843871 )
2016
44
Urinary levels of early kidney injury molecules in children with vitamin B12 deficiency. ( 27606644 )
2016
45
Visual and somotosensory evoked potentials in asymptomatic patients with vitamin B12 deficiency. ( 27874946 )
2016
46
Severe but Not Moderate Vitamin B12 Deficiency Impairs Lipid Profile, Induces Adiposity, and Leads to Adverse Gestational Outcome in Female C57BL/6 Mice. ( 26835453 )
2016
47
Reversible Cutaneous Hyperpigmentation in Vitamin B12 Deficiency. ( 27731562 )
2016
48
Subclinical vitamin B12 deficiency and heart rate variability across life cycle. ( 26864037 )
2016
49
Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study. ( 26900641 )
2016
50
Hematogones detected by flow cytometry in a child with vitamin B12 deficiency: A case report. ( 27285990 )
2016

Variations for Vitamin B12 Deficiency

Expression for Vitamin B12 Deficiency

Search GEO for disease gene expression data for Vitamin B12 Deficiency.

Pathways for Vitamin B12 Deficiency

Pathways related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.16 GIF MTHFR MTR TCN1 TCN2
2
Show member pathways
11.9 GPT MTHFR MTR
3
Show member pathways
11.69 GIF MTHFR MTR TCN1 TCN2
4
Show member pathways
11.65 MTHFR MTR TCN2
5
Show member pathways
11.42 GIF MTR TCN2
6 11.11 EPO TF
7 10.75 GIF TCN2
8 10.27 GIF MTR TCN1 TCN2

GO Terms for Vitamin B12 Deficiency

Cellular components related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 EPO GIF GPT TCN1 TCN2 TF

Biological processes related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ion transport GO:0006811 9.71 GIF TCN1 TCN2 TF
2 blood circulation GO:0008015 9.46 EPO MTHFR
3 cellular amino acid biosynthetic process GO:0008652 9.43 GPT MTR
4 response to hypoxia GO:0001666 9.43 ADAM17 EPO MTHFR
5 response to interleukin-1 GO:0070555 9.37 EPO MTHFR
6 cobalamin transport GO:0015889 9.33 GIF TCN1 TCN2
7 response to axon injury GO:0048678 9.32 EPO MTR
8 cobalt ion transport GO:0006824 9.13 GIF TCN1 TCN2
9 cobalamin metabolic process GO:0009235 8.92 GIF MTR TCN1 TCN2

Molecular functions related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cobalamin binding GO:0031419 8.92 GIF MTR TCN1 TCN2

Sources for Vitamin B12 Deficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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