MCID: VTM002
MIFTS: 46

Vitamin B12 Deficiency

Categories: Metabolic diseases

Aliases & Classifications for Vitamin B12 Deficiency

MalaCards integrated aliases for Vitamin B12 Deficiency:

Name: Vitamin B12 Deficiency 12 51 14
Cobalamin Deficiency 12 28
Vitamin B 12 Deficiency 69
Hypocobalaminemia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050731
UMLS 69 C0042847

Summaries for Vitamin B12 Deficiency

Disease Ontology : 12 A vitamin metabolic disorder that results from low blood levels of vitamin B12.

MalaCards based summary : Vitamin B12 Deficiency, also known as cobalamin deficiency, is related to pernicious anemia and transcobalamin ii deficiency. An important gene associated with Vitamin B12 Deficiency is MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase), and among its related pathways/superpathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. The drugs Hydroxocobalamin and Iron have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and testes, and related phenotypes are Increased shRNA abundance and homeostasis/metabolism

Related Diseases for Vitamin B12 Deficiency

Diseases related to Vitamin B12 Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 186)
# Related Disease Score Top Affiliating Genes
1 pernicious anemia 32.8 GIF TCN1 TCN2
2 transcobalamin ii deficiency 31.5 GIF MTHFR MTR TCN1 TCN2
3 megaloblastic anemia 31.4 GIF MTHFR MTR TCN1 TCN2
4 neural tube defects, folate-sensitive 30.3 MTHFR MTR
5 iron metabolism disease 30.2 EPO TF
6 homocystinuria 30.1 MTHFR MTR TCN2
7 deficiency anemia 30.0 EPO PON1 TF
8 hemoglobin h disease 29.8 EPO TF
9 iron deficiency anemia 29.7 EPO TF
10 neural tube defects 29.1 MTHFR MTR TCN2
11 megaloblastic anemia 1 11.6
12 congenital intrinsic factor deficiency 11.5
13 atrophic gastritis 11.4
14 diphyllobothriasis 11.0
15 blind loop syndrome 11.0
16 autoimmune atrophic gastritis 11.0
17 bothriocephalosis 11.0
18 homocystinuria due to deficiency of n -methylenetetrahydrofolate reductase activity 10.5 MTHFR MTR
19 neuropathy 10.4
20 ariboflavinosis 10.4 MTHFR TF
21 amino acid metabolic disorder 10.4 MTHFR MTR
22 myelomeningocele 10.4 MTHFR MTR
23 ophthalmia neonatorum 10.3 CD79A MTR
24 dowling-degos disease 1 10.3
25 marasmus 10.3 CD79A TF
26 gamma heavy chain disease 10.3 CD79A GIF
27 yellow nail syndrome 10.3 CD79A TF
28 small intestine lymphoma 10.3 CD79A GIF
29 dementia 10.3
30 central nervous system lymphoma 10.3 MTR TCN2
31 aging 10.2
32 pancytopenia 10.2
33 lipoid nephrosis 10.2 CD79A TF
34 dysentery 10.2 CD79A TF
35 vernal conjunctivitis 10.2 CD79A TF
36 pure red-cell aplasia 10.2 EPO TF
37 stomach disease 10.2 CD79A GIF
38 methylmalonic aciduria, cblb type 10.2 MTHFR MTR TCN2
39 diabetes mellitus 10.1
40 multiple sclerosis 10.1
41 thrombotic thrombocytopenic purpura 10.1
42 purpura 10.1
43 galactosemia 10.1 GIF TF
44 hemoglobinopathy 10.1 EPO TF
45 microcytic anemia 10.1 EPO TF
46 phenylketonuria 10.0
47 cerebritis 10.0
48 gastritis 10.0
49 folic acid deficiency anemia 10.0 EPO GIF TF
50 parasitic protozoa infectious disease 10.0 CD79A TCN2

Graphical network of the top 20 diseases related to Vitamin B12 Deficiency:



Diseases related to Vitamin B12 Deficiency

Symptoms & Phenotypes for Vitamin B12 Deficiency

GenomeRNAi Phenotypes related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance GR00327-A 8.92 CD79A EPO MTHFR MTR

MGI Mouse Phenotypes related to Vitamin B12 Deficiency:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.23 ACADVL CD79A EPO GIF MTHFR MTR

Drugs & Therapeutics for Vitamin B12 Deficiency

Drugs for Vitamin B12 Deficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 73)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydroxocobalamin Approved Phase 4,Phase 2,Phase 3 13422-51-0 5460373 44475014 11953898
2
Iron Approved Phase 4 7439-89-6 23925
3
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
4
Cyanocobalamin Approved, Nutraceutical Phase 4,Phase 2,Phase 3 68-19-9 44176380
5
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3 59-30-3 6037
6
Methylcobalamin Approved, Experimental, Investigational, Nutraceutical Phase 4,Phase 2,Phase 3 13422-55-4
7
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 68-26-8, 11103-57-4 445354
8 Tocopherol Approved, Investigational, Nutraceutical Phase 4
9
Vitamin E Approved, Nutraceutical, Vet_approved Phase 4 59-02-9 14985
10
Pyridoxal Approved, Nutraceutical Phase 4,Phase 3 66-72-8 1050
11
Pyridoxine Approved, Investigational, Nutraceutical, Vet_approved Phase 4,Phase 3 65-23-6 1054
12
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 4 59-43-8 1130
13 Hematinics Phase 4,Phase 2,Phase 3
14 Micronutrients Phase 4,Phase 2,Phase 3
15 Retinol palmitate Phase 4
16 Trace Elements Phase 4,Phase 2,Phase 3
17 Vitamin B 12 Phase 4,Phase 2,Phase 3
18 Vitamin B Complex Phase 4,Phase 2,Phase 3
19 Vitamins Phase 4,Phase 2,Phase 3
20 Antacids Phase 4
21 Anti-Ulcer Agents Phase 4
22 Gastrointestinal Agents Phase 4
23 Proton pump inhibitors Phase 4
24 Antioxidants Phase 4,Phase 2
25 Protective Agents Phase 4
26 Tocopherols Phase 4
27 Tocotrienols Phase 4
28 Vitamin B 6 Phase 4,Phase 3
29
Cobalamin Nutraceutical Phase 4,Phase 2,Phase 3 13408-78-1 6438156
30 Folate Nutraceutical Phase 4,Phase 2,Phase 3
31 retinol Nutraceutical Phase 4
32 Vitamin B12 Nutraceutical Phase 4,Phase 2,Phase 3
33 Vitamin B9 Nutraceutical Phase 4,Phase 2,Phase 3
34 Tocotrienol Investigational, Nutraceutical Phase 4 6829-55-6
35 Thiamin Nutraceutical Phase 4
36
Levodopa Approved Phase 2, Phase 3 59-92-7 6047
37
leucovorin Approved, Nutraceutical Phase 2, Phase 3 58-05-9 143 6006
38 Vaccines Phase 2, Phase 3
39 Ubiquinone Phase 2
40
Metformin Approved 657-24-9 4091 14219
41
Acetylcysteine Approved, Investigational 616-91-1 12035
42
Nitrous oxide Approved, Vet_approved 10024-97-2 948
43
Dextromethorphan Approved 125-71-3 5362449 5360696
44
Memantine Approved, Investigational 19982-08-2 4054
45
Quinidine Approved, Investigational 56-54-2 441074
46
Vitamin D Approved, Nutraceutical, Vet_approved 1406-16-2
47 Antidepressive Agents
48 Neurotransmitter Agents
49 Neurotransmitter Uptake Inhibitors
50 Psychotropic Drugs

Interventional clinical trials:

(show top 50) (show all 57)

# Name Status NCT ID Phase Drugs
1 Vitamin Deficiencies and Suppletion in Morbid Obesity Unknown status NCT02270749 Phase 4 Hydroxocobalamin;FitForMe vitamin B12
2 How Many Patients Are in Need of Vitamin B12 Injections? Unknown status NCT00326833 Phase 4 vitamin B12
3 Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC Unknown status NCT01795794 Phase 4 omeprazole
4 The Role of Methycobalamin in Early Dementia Patients With Vitamin B12 Deficiency and Hyperhomocysteinaemia. Completed NCT00165711 Phase 4 Mecobalamin
5 Vitamin B12 Acceptance and Biomarker Response Study Completed NCT01832129 Phase 4 Oral administration of vitamin B12;i.m. injection of vitamin B12
6 Vitamin B12 Supplement to Prevent Cognitive Decline Completed NCT02457507 Phase 4
7 Postoperative Vitamin Supplementation in Morbidly Obese Patient (VITAAL Study) Completed NCT01609387 Phase 4
8 Megadose of Hydroxocobalamin for the Treatment of Pernicious Anemia Recruiting NCT03372447 Phase 4 Hydroxocobalamin 10,000mcg, Thiamin 100mg, Pyridoxine 50mg
9 Vitamin B12 Supplementation During Pregnancy Completed NCT01795131 Phase 2, Phase 3
10 Study of Pylopass Versus Placebo in Subjects Who Are Helicobacter Pylori Carriers and With Mild Indigestion Completed NCT02051348 Phase 2, Phase 3
11 WENBIT - Western Norway B Vitamin Intervention Trial Completed NCT00354081 Phase 3 folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine);folic acid, vitamin B12 (cyanocobalamin);vitamin B6 (pyridoxine);placebo
12 Vitamin B12 Supplementation During Pregnancy on Cognitive Development Recruiting NCT03071666 Phase 2, Phase 3
13 Vitamin B12, Neurodevelopment and Growth in Nepal Active, not recruiting NCT02272842 Phase 2, Phase 3
14 Vitamin B12 Status and Response to Vitamin B12 Supplementation in Patients With Parkinson's Disease Terminated NCT00208611 Phase 2, Phase 3
15 Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy Completed NCT00699478 Phase 2 mecobalamin
16 Can Recombinant Human Intrinsic Factor Be Used for Evaluation of the Vitamin B12 Absorption? Completed NCT00279552 Phase 2 Recombinant human intrinsic factor
17 EPI-743 in Cobalamin C Defect: Effects on Visual and Neurological Impairment Completed NCT01793090 Phase 2 Epi-743
18 Cracking the Egg Potential: Improving Young Child Nutrition in Ecuador Unknown status NCT02446873
19 Comparison of Vitamin B12 Supplementation to Selective Serotonin Reuptake Inhibitor (SSRI) Versus SSRI Antidepressant Treatment Alone Unknown status NCT00939718
20 Resting Energy Expenditure and Nutritional Status in IBD Unknown status NCT02275676
21 Long-term Use of Proton Pump Inhibitors May Cause Vitamin B12 Deficiency in the Institutionalized Elderly Completed NCT00843453 treatment (cyanocobalamin nasal spray)
22 Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients Completed NCT01876329
23 Oral/Intramuscular B12 to Treat Cobalamin Deficiency Completed NCT01476007 oral Cobalamin (vitamin B12);intramuscular Cobalamin (vitamin B12)
24 Metformin Use and Vitamin B12 Deficiency Completed NCT01136512
25 Vitamin B12 Supplementation Study Completed NCT00826657
26 Impact of Vitamin B12 Replacement on Epogen Dosing and Improvement of Quality of Life in Hemodialysis Patients Completed NCT01876732 Vitamin B12
27 Cobalamin Status in Young Children With Gastrointestinal Symptoms or Feeding Problems Completed NCT00710359
28 Cobalamin Status in Young Children With Developmental Delay Completed NCT00710138
29 The Association Between Religious Origin and Age, and Vitamin B12 and Folic Acid Plasma Levels in Non Jewish Population in Western Galilee Completed NCT01297361
30 Study to Identify Adequate Biomarker to Detect Vitamin B12 Deficiency in Type 2 Diabetic Patients Treated With Metformin Completed NCT02111967
31 Cobalamin Supplementation During Infancy; Effect on B-vitamin Status, Growth and Psychomotor Development Completed NCT00479479 Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
32 Relative Bioavailability of Folic Acid and L-5-Methlytetrahydrofolate Completed NCT01584050
33 Efficacy and Safety Study of Oral Eligen® B12 in Subjects With Low Serum Cobalamin Completed NCT01312831
34 Holotranscobalamin Remains Unchanged During Pregnancy Completed NCT00467623
35 Supplementary Vitamin B12 Effects on Elevated Homocysteine Levels of Vegetarians - Clinical Trial Completed NCT01661309
36 Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin Completed NCT02076347
37 Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status Completed NCT02679833
38 Study of the Association of Muscle Strength, Balance and Other Factors With Vitamin Levels Among Elderly Diabetics Completed NCT03376490
39 Cobalamin Absorption From Fortified Food Completed NCT01399164
40 Effect of Vitamin B12 Supplementation on Glycaemic Control in Uncontrolled Hyperhomocysteinemic Type 2 Diabetic Patients Completed NCT02540642
41 The Vitamin B Status in Type 2 Diabetes (VITA) Study Completed NCT03447275
42 Oral Vitamin B12 Supplementation and Cognitive Performance in Elderly People Completed NCT00111267
43 Evaluation of Holotranscobalamin as an Indicator of Vitamin B12 Absorption Completed NCT00235573
44 NAC-003 P.L.U.S. Program (Progress Through Learning Understanding & Support) Completed NCT01370954
45 The Bread Trial: Effects of Bread Fortified With Folic Acid and Vitamin B12 Completed NCT00353353
46 Acid Suppressive Therapy - Review of Appropriateness Completed NCT02259270
47 Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly Completed NCT00212147 general anesthesia
48 B Vitamin Status in Premature and Small for Gestational Age(SGA) Infants Completed NCT01201005
49 Natural Versus Synthetic Vitamin B Complexes in Human Completed NCT03444155
50 COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE Completed NCT02860338

Search NIH Clinical Center for Vitamin B12 Deficiency

Genetic Tests for Vitamin B12 Deficiency

Genetic tests related to Vitamin B12 Deficiency:

# Genetic test Affiliating Genes
1 Cobalamin Deficiency 28

Anatomical Context for Vitamin B12 Deficiency

MalaCards organs/tissues related to Vitamin B12 Deficiency:

38
Spinal Cord, Bone, Testes, Brain, Colon, Skin, Heart

Publications for Vitamin B12 Deficiency

Articles related to Vitamin B12 Deficiency:

(show top 50) (show all 650)
# Title Authors Year
1
Identification of vitamin B12 deficiency in vegetarian Indians. ( 29446340 )
2018
2
Evaluation of Vitamin B12 Deficiency and Associated Factors in Patients With Systemic Sclerosis. ( 29384828 )
2018
3
Vitamin B12 deficiency and impaired expression of amnionless during aging. ( 29159972 )
2018
4
Investigation of the vitamin B12 deficiency with peripheral neuropathy in patients with type 2 diabetes mellitus treated using metformin. ( 29270571 )
2017
5
Vitamin B12-Loaded Buccoadhesive Films as a Noninvasive Supplement in Vitamin B12 Deficiency: InA Vitro Evaluation and InA Vivo Comparative Study With Intramuscular Injection. ( 28400198 )
2017
6
Corrigendum: Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency. ( 28798917 )
2017
7
Perspectives on Peripheral Neuropathy as a Consequence of Metformin-Induced Vitamin B12 Deficiency in T2DM. ( 28932240 )
2017
8
Pseudothrombotic microangiopathy and vitamin B12 deficiency in pernicious anemia. ( 28670082 )
2017
9
The Efficacy of Oral Vitamin B12 Replacement for Nutritional Vitamin B12 Deficiency. ( 29189512 )
2017
10
Nitrous oxide-induced vitamin B12 deficiency. ( 28405070 )
2017
11
Microangiopathic Hemolytic Anemia - A Rare Presentation of Vitamin B12 Deficiency. ( 29071581 )
2017
12
Recurrent anaemia in a patient with lymphocytic gastritis and vitamin B12 deficiency. ( 28943131 )
2017
13
The risks of folic acid to the nervous system in vitamin B12 deficiency: rediscovered in the era of folic acid fortification policies. ( 28596250 )
2017
14
Methylcobalamin in Vitamin B12 Deficiency: To Give or not to Give? ( 28405134 )
2017
15
The histopathological evaluation of small fiber neuropathy in patients with vitamin B12 deficiency. ( 29052170 )
2017
16
Response to 'Vitamin B12 deficiency may coexist with endocrine causes of hyperpigmentation'. ( 29025026 )
2017
17
Behavioral alterations are associated with vitamin B12 deficiency in the transcobalamin receptor/CD320 KO mouse. ( 28545069 )
2017
18
Re: Vitamin B12 Deficiency in Patients after Enterocystoplasty. ( 28618704 )
2017
19
Metformin Use and Vitamin B12 Deficiency: Untangling the Association. ( 28864375 )
2017
20
Characteristics of Vitamin B12 Deficiency in Patients With Plasma Cell Disorders. ( 28757000 )
2017
21
Association between the MTHFR C677T polymorphism, blood folate and vitamin B12 deficiency, and elevated serum total homocysteine in healthy individuals in Yunnan Province, China. ( 28094233 )
2017
22
Vitamin B12 Deficiency: Recognition and Management. ( 28925645 )
2017
23
Vitamin B12 deficiency. ( 28660890 )
2017
24
Prevalence of Vitamin B12 Deficiency in Patients with Type II Diabetes Mellitus on Metformin: A Study from Khyber Pakhtunkhwa. ( 29057189 )
2017
25
Correction: Vitamin B12 deficiency. ( 28726793 )
2017
26
Efficacy of oral methylcobalamin in treatment of vitamin B12 deficiency anemia in children. ( 28667789 )
2017
27
Vitamin B12 deficiency in inflammatory bowel disease: a prospective observational pilot study. ( 28953003 )
2017
28
Vitamin B12 deficiency might be related to sarcopenia in older adults. ( 28549839 )
2017
29
High Serum Folate Is Associated with Brain Atrophy in Older Diabetic People with Vitamin B12 Deficiency. ( 29083449 )
2017
30
Vitamin B12 deficiency. ( 28660905 )
2017
31
Oxidative Stress, Hepcidin and Nesfatin-I Status in Childhood Iron and Vitamin B12 Deficiency Anemias. ( 28691407 )
2017
32
Subclinical vitamin B12 deficiency and heart rate variability across life cycle. ( 26864037 )
2016
33
Vitamin B12 Deficiency in Infancy: The Case for Screening. ( 26806811 )
2016
34
Can vitamin B12 deficiency manifest with acute posterolateral or posterior cord syndrome? ( 28053750 )
2016
35
When the picture is fragmented: Vitamin B12 deficiency masquerading as thrombotic thrombocytopenic purpura. ( 27308258 )
2016
36
A observational study in patients of diabetes using metformin causing vitamin B12 deficiency causing peripheral neuropathy. ( 27728101 )
2016
37
Study of correlation between vitamin B12 deficiency and clinical, haematological and electrophysiological parameters. ( 27728753 )
2016
38
Vitamin B12 Deficiency Induced by the Use of Gastric Acid Inhibitors: Calcium Supplements as a Potential Effect Modifier. ( 27102797 )
2016
39
Delayed auditory conduction in diabetes: is metformin-induced vitamin B12 deficiency responsible? ( 27358222 )
2016
40
Erratum: Study of Vitamin B12 deficiency and peripheral neuropathy in metformin-treated early Type 2 diabetes mellitus. ( 27867908 )
2016
41
Metformin and Vitamin B12 Deficiency: Where Do We Stand? ( 27806244 )
2016
42
Association of Vitamin B12 Deficiency and Use of Reverse Osmosis Processed Water for Drinking: A Cross-Sectional Study from Western India. ( 27437269 )
2016
43
Severe but Not Moderate Vitamin B12 Deficiency Impairs Lipid Profile, Induces Adiposity, and Leads to Adverse Gestational Outcome in Female C57BL/6 Mice. ( 26835453 )
2016
44
Vitamin B12 deficiency results in severe oxidative stress, leading to memory retention impairment in Caenorhabditis elegans. ( 27840283 )
2016
45
Evaluation of Reticulocyte Parameters in Iron Deficiency, Vitamin B12 Deficiency and Mixed Anemia. ( 27156322 )
2016
46
Holotranscobalamin (HoloTC, Active-B12) and Herbert's model for the development of vitamin B12 deficiency: a review and alternative hypothesis. ( 27350907 )
2016
47
Zotepine-associated vitamin B12 deficiency and pancytopenia. ( 27872328 )
2016
48
Reference interval of methylmalonic acid concentrations in dried blood spots of healthy, term newborns to facilitate neonatal screening of vitamin B12 deficiency. ( 27040901 )
2016
49
Drug-Induced Vitamin B12 Deficiency: A Focus on Proton Pump Inhibitors and Histamine-2 Antagonists. ( 27520327 )
2016
50
Prevalence of vitamin B12 deficiency in type 2 diabetic patients using metformin: a cross-sectional study. ( 27276084 )
2016

Variations for Vitamin B12 Deficiency

Expression for Vitamin B12 Deficiency

Search GEO for disease gene expression data for Vitamin B12 Deficiency.

Pathways for Vitamin B12 Deficiency

Pathways related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.64 ACADVL GIF GPT MTHFR MTR PON1
2
Show member pathways
12.16 GIF MTHFR MTR TCN1 TCN2
3
Show member pathways
11.93 GPT MTHFR MTR
4
Show member pathways
11.69 GIF MTHFR MTR TCN1 TCN2
5
Show member pathways
11.65 MTHFR MTR TCN2
6
Show member pathways
11.42 GIF MTR TCN2
7 11.14 EPO TF
8 10.75 GIF TCN2
9 10.27 GIF MTR TCN1 TCN2

GO Terms for Vitamin B12 Deficiency

Cellular components related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 EPO GIF PON1 TCN1 TCN2 TF
2 extracellular space GO:0005615 9.17 EPO GIF GPT PON1 TCN1 TCN2

Biological processes related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ion transport GO:0006811 9.67 GIF TCN1 TCN2 TF
2 cellular amino acid biosynthetic process GO:0008652 9.43 GPT MTR
3 blood circulation GO:0008015 9.4 EPO MTHFR
4 cobalamin transport GO:0015889 9.33 GIF TCN1 TCN2
5 response to interleukin-1 GO:0070555 9.32 EPO MTHFR
6 response to axon injury GO:0048678 9.26 EPO MTR
7 cobalt ion transport GO:0006824 9.13 GIF TCN1 TCN2
8 cobalamin metabolic process GO:0009235 8.92 GIF MTR TCN1 TCN2

Molecular functions related to Vitamin B12 Deficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin binding GO:0031419 8.92 GIF MTR TCN1 TCN2

Sources for Vitamin B12 Deficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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