MCID: VTM021
MIFTS: 12

Vitamin K Antagonists Toxicity or Dose Selection malady

Categories: Rare diseases

Aliases & Classifications for Vitamin K Antagonists Toxicity or Dose Selection

Aliases & Descriptions for Vitamin K Antagonists Toxicity or Dose Selection:

Name: Vitamin K Antagonists Toxicity or Dose Selection 56

Classifications:



External Ids:

Orphanet 56 ORPHA413674

Summaries for Vitamin K Antagonists Toxicity or Dose Selection

MalaCards based summary : Vitamin K Antagonists Toxicity or Dose Selection is related to discoid lupus erythematosus and undifferentiated carcinoma of esophagus. An important gene associated with Vitamin K Antagonists Toxicity or Dose Selection is CYP2C9 (Cytochrome P450 Family 2 Subfamily C Member 9), and among its related pathways/superpathways are Arachidonic acid metabolism and Linoleic acid metabolism.

Related Diseases for Vitamin K Antagonists Toxicity or Dose Selection

Diseases related to Vitamin K Antagonists Toxicity or Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 discoid lupus erythematosus 9.9 CYP2C9 VKORC1
2 undifferentiated carcinoma of esophagus 9.6 CYP2C9 CYP4F2 VKORC1
3 kawasaki disease 9.5 CYP2C9 CYP4F2 VKORC1

Symptoms & Phenotypes for Vitamin K Antagonists Toxicity or Dose Selection

Drugs & Therapeutics for Vitamin K Antagonists Toxicity or Dose Selection

Search Clinical Trials , NIH Clinical Center for Vitamin K Antagonists Toxicity or Dose Selection

Genetic Tests for Vitamin K Antagonists Toxicity or Dose Selection

Anatomical Context for Vitamin K Antagonists Toxicity or Dose Selection

Publications for Vitamin K Antagonists Toxicity or Dose Selection

Variations for Vitamin K Antagonists Toxicity or Dose Selection

Expression for Vitamin K Antagonists Toxicity or Dose Selection

Search GEO for disease gene expression data for Vitamin K Antagonists Toxicity or Dose Selection.

Pathways for Vitamin K Antagonists Toxicity or Dose Selection

GO Terms for Vitamin K Antagonists Toxicity or Dose Selection

Cellular components related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum membrane GO:0005789 9.13 CYP2C9 CYP4F2 VKORC1
2 organelle membrane GO:0031090 8.62 CYP2C9 CYP4F2

Biological processes related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.43 CYP2C9 CYP4F2 VKORC1
2 blood coagulation GO:0007596 9.32 CYP4F2 VKORC1
3 epoxygenase P450 pathway GO:0019373 9.16 CYP2C9 CYP4F2
4 omega-hydroxylase P450 pathway GO:0097267 8.96 CYP2C9 CYP4F2
5 drug metabolic process GO:0017144 8.8 CYP2C9 CYP4F2 VKORC1

Molecular functions related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 iron ion binding GO:0005506 9.37 CYP2C9 CYP4F2
2 oxidoreductase activity GO:0016491 9.33 CYP2C9 CYP4F2 VKORC1
3 heme binding GO:0020037 9.32 CYP2C9 CYP4F2
4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.26 CYP2C9 CYP4F2
5 monooxygenase activity GO:0004497 8.96 CYP2C9 CYP4F2
6 arachidonic acid epoxygenase activity GO:0008392 8.62 CYP2C9 CYP4F2

Sources for Vitamin K Antagonists Toxicity or Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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37 KEGG
38 LifeMap
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42 MeSH
43 MESH via Orphanet
44 MGI
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48 NDF-RT
51 NINDS
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54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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