MCID: VTM021
MIFTS: 13

Vitamin K Antagonists Toxicity or Dose Selection

Categories: Rare diseases

Aliases & Classifications for Vitamin K Antagonists Toxicity or Dose Selection

MalaCards integrated aliases for Vitamin K Antagonists Toxicity or Dose Selection:

Name: Vitamin K Antagonists Toxicity or Dose Selection 55

Classifications:



External Ids:

Orphanet 55 ORPHA413674

Summaries for Vitamin K Antagonists Toxicity or Dose Selection

MalaCards based summary : Vitamin K Antagonists Toxicity or Dose Selection is related to diffuse alveolar hemorrhage and atrial fibrillation. Among its related pathways/superpathways are Arachidonic acid metabolism and Linoleic acid metabolism.

Related Diseases for Vitamin K Antagonists Toxicity or Dose Selection

Diseases related to Vitamin K Antagonists Toxicity or Dose Selection via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 diffuse alveolar hemorrhage 9.7 CYP2C9 VKORC1
2 atrial fibrillation 9.3 CYP4F2 VKORC1
3 coumarin resistance 9.1 CYP2C9 CYP4F2 VKORC1

Symptoms & Phenotypes for Vitamin K Antagonists Toxicity or Dose Selection

Drugs & Therapeutics for Vitamin K Antagonists Toxicity or Dose Selection

Search Clinical Trials , NIH Clinical Center for Vitamin K Antagonists Toxicity or Dose Selection

Genetic Tests for Vitamin K Antagonists Toxicity or Dose Selection

Anatomical Context for Vitamin K Antagonists Toxicity or Dose Selection

Publications for Vitamin K Antagonists Toxicity or Dose Selection

Variations for Vitamin K Antagonists Toxicity or Dose Selection

Expression for Vitamin K Antagonists Toxicity or Dose Selection

Search GEO for disease gene expression data for Vitamin K Antagonists Toxicity or Dose Selection.

Pathways for Vitamin K Antagonists Toxicity or Dose Selection

GO Terms for Vitamin K Antagonists Toxicity or Dose Selection

Cellular components related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.33 CYP2C9 CYP4F2 VKORC1
2 endoplasmic reticulum membrane GO:0005789 9.13 CYP2C9 CYP4F2 VKORC1
3 organelle membrane GO:0031090 8.62 CYP2C9 CYP4F2

Biological processes related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.43 CYP2C9 CYP4F2 VKORC1
2 blood coagulation GO:0007596 9.32 CYP4F2 VKORC1
3 epoxygenase P450 pathway GO:0019373 9.16 CYP2C9 CYP4F2
4 omega-hydroxylase P450 pathway GO:0097267 8.96 CYP2C9 CYP4F2
5 drug metabolic process GO:0017144 8.8 CYP2C9 CYP4F2 VKORC1

Molecular functions related to Vitamin K Antagonists Toxicity or Dose Selection according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 iron ion binding GO:0005506 9.37 CYP2C9 CYP4F2
2 heme binding GO:0020037 9.32 CYP2C9 CYP4F2
3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.26 CYP2C9 CYP4F2
4 monooxygenase activity GO:0004497 9.16 CYP2C9 CYP4F2
5 oxidoreductase activity GO:0016491 9.13 CYP2C9 CYP4F2 VKORC1
6 arachidonic acid epoxygenase activity GO:0008392 8.62 CYP2C9 CYP4F2

Sources for Vitamin K Antagonists Toxicity or Dose Selection

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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