MCID: VTM001
MIFTS: 29

Vitamin K Deficiency Hemorrhagic Disease malady

Metabolic diseases category

Aliases & Classifications for Vitamin K Deficiency Hemorrhagic Disease

About this section

Aliases & Descriptions for Vitamin K Deficiency Hemorrhagic Disease:

Name: Vitamin K Deficiency Hemorrhagic Disease 10 12
Vitamin K Deficiency 10 47 65 36
Vitamin K Deficiency Coagulation Disorder 65
 
Deficiency of Vitamin K 10
Vitamin K 35


Classifications:



External Ids:

Disease Ontology10 DOID:11249
ICD9CM29 269.0
SNOMED-CT59 52675005, 124892003
MeSH36 D014813
ICD1027 E56.1

Summaries for Vitamin K Deficiency Hemorrhagic Disease

About this section
MedlinePlus:35 Vitamin k helps your body by making proteins for healthy bones and tissues. it also makes proteins for blood clotting. if you don't have enough vitamin k, you may bleed too much. newborns have very little vitamin k. they usually get a shot of vitamin k soon after they are born. if you take blood thinners, you need to be careful about how much vitamin k you get. you also need to be careful about taking vitamin e supplements. vitamin e can interfere with how vitamin k works in your body. ask your health care provider for recommendations about these vitamins. there are different types of vitamin k. most people get vitamin k from plants such as green vegetables, and dark berries. bacteria in your intestines also produce small amounts of another type of vitamin k.

MalaCards based summary: Vitamin K Deficiency Hemorrhagic Disease, also known as vitamin k deficiency, is related to thrombophilia due to thrombin defect and blood protein disease. An important gene associated with Vitamin K Deficiency Hemorrhagic Disease is F2 (Coagulation Factor II (Thrombin)), and among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2 and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include bone, and related mouse phenotypes are cardiovascular system and homeostasis/metabolism.

Related Diseases for Vitamin K Deficiency Hemorrhagic Disease

About this section

Diseases related to Vitamin K Deficiency Hemorrhagic Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 560)
idRelated DiseaseScoreTop Affiliating Genes
1thrombophilia due to thrombin defect30.9F2, F3
2blood protein disease30.5F2, F3
3factor x deficiency30.4F2, F3
4galactosemia30.1AFP, BGLAP, F2, F3
5viral infectious disease30.0AFP, F2
6hypoprothrombinemia10.8
7vascular hemostatic disease10.7
8prothrombin deficiency10.7
9atrial fibrillation10.6
10hepatocellular carcinoma10.6
11greenberg skeletal dysplasia10.6
12familial atrial fibrillation10.6
13blood coagulation disease10.6
14factor v leiden thrombophilia10.6
15vitamin metabolic disorder10.5
16hereditary combined deficiency of vitamin k-dependent clotting factors10.5
17calcinosis10.5
18kidney disease10.5
19stroke, ischemic10.5
20coronary heart disease 210.5
21atrial fibrillation and stroke10.5
22vitamin k-dependent clotting factors, combined deficiency of, 110.4
23coronary heart disease 310.4
24bone fracture10.4
25calcium metabolism disease10.4
26coronary heart disease 410.4
27chronic kidney failure10.4
28heart valve disease10.4
29coronary thrombosis10.4
30metabolic syndrome x10.4
31myocardial infarction10.4
32coagulation protein disease10.4
33primary hyperoxaluria10.4
34secondary syphilis10.4
35bone remodeling disease10.4
36vascular disease10.4
37vein disease10.4
38marchiafava bignami disease10.4
39coronary artery disease10.3
40coronary heart disease 510.3
41aortic valve disease 210.3
42ischemic heart disease10.3
43calciphylaxis10.3
44aortic disease10.3
45congenital heart disease10.3
46impaired renal function disease10.3
47mineral metabolism disease10.3
48biliary atresia10.3
49chondrodysplasia punctata10.3
50diabetes mellitus, noninsulin-dependent10.3

Graphical network of the top 20 diseases related to Vitamin K Deficiency Hemorrhagic Disease:



Diseases related to vitamin k deficiency hemorrhagic disease

Symptoms for Vitamin K Deficiency Hemorrhagic Disease

About this section

Drugs & Therapeutics for Vitamin K Deficiency Hemorrhagic Disease

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Vitamin K Deficiency Hemorrhagic Disease


Cochrane evidence based reviews: Vitamin K Deficiency

Genetic Tests for Vitamin K Deficiency Hemorrhagic Disease

About this section

Anatomical Context for Vitamin K Deficiency Hemorrhagic Disease

About this section

MalaCards organs/tissues related to Vitamin K Deficiency Hemorrhagic Disease:

33
Bone

Animal Models for Vitamin K Deficiency Hemorrhagic Disease or affiliated genes

About this section

MGI Mouse Phenotypes related to Vitamin K Deficiency Hemorrhagic Disease:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.7F2, F3, GGCX, MGP, PROS1
2MP:00053766.8AFP, F2, F3, GGCX, MGP, PROS1

Publications for Vitamin K Deficiency Hemorrhagic Disease

About this section

Variations for Vitamin K Deficiency Hemorrhagic Disease

About this section

Expression for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

About this section
Search GEO for disease gene expression data for Vitamin K Deficiency Hemorrhagic Disease.

Pathways for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

About this section

Pathways related to Vitamin K Deficiency Hemorrhagic Disease according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7BGLAP, MGP
29.7AFP, F2
3
Show member pathways
9.1GGCX, VKORC1
4
Show member pathways
9.0F2, F3, PROS1
5
Show member pathways
9.0F2, F3, PROS1
6
Show member pathways
9.0F2, F3, PROS1
7
Show member pathways
8.2F2, GGCX, PROS1, VKORC1
87.4BGLAP, F2, GGCX, MGP, PROS1, VKORC1

GO Terms for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

About this section

Cellular components related to Vitamin K Deficiency Hemorrhagic Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrixGO:00310128.9F2, F3, MGP
2extracellular spaceGO:00056158.2AFP, BGLAP, F2, F3, PROS1

Biological processes related to Vitamin K Deficiency Hemorrhagic Disease according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1regulation of bone mineralizationGO:003050010.1BGLAP, MGP
2response to woundingGO:000961110.1F2, F3
3fibrinolysisGO:004273010.1F2, PROS1
4bone developmentGO:00603489.8BGLAP, VKORC1
5response to mechanical stimulusGO:00096129.8BGLAP, F3
6peptidyl-glutamic acid carboxylationGO:00171878.7F2, GGCX, PROS1, VKORC1
7post-translational protein modificationGO:00436878.4F2, GGCX, PROS1, VKORC1
8cellular protein metabolic processGO:00442678.4F2, GGCX, PROS1, VKORC1
9blood coagulationGO:00075967.6F2, F3, GGCX, PROS1, VKORC1

Molecular functions related to Vitamin K Deficiency Hemorrhagic Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of boneGO:000814710.3BGLAP, MGP
2calcium ion bindingGO:00055098.7BGLAP, F2, MGP, PROS1

Sources for Vitamin K Deficiency Hemorrhagic Disease

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet