MCID: VTM001
MIFTS: 28

Vitamin K Deficiency Hemorrhagic Disease malady

Category: Metabolic diseases

Aliases & Classifications for Vitamin K Deficiency Hemorrhagic Disease

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Aliases & Descriptions for Vitamin K Deficiency Hemorrhagic Disease:

Name: Vitamin K Deficiency Hemorrhagic Disease 10 12
Vitamin K Deficiency 10 47 36 65
 
Deficiency of Vitamin K 10
Vitamin K 35

Classifications:



External Ids:

Disease Ontology10 DOID:11249
ICD1027 E56.1
SNOMED-CT59 124892003, 52675005
ICD9CM29 269.0
MeSH36 D014813
UMLS65 C0042880

Summaries for Vitamin K Deficiency Hemorrhagic Disease

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MedlinePlus:35 Vitamins are substances that your body needs to grow and develop normally. vitamin k helps your body by making proteins for healthy bones and tissues. it also makes proteins for blood clotting. if you don't have enough vitamin k, you may bleed too much. newborns have very little vitamin k. they usually get a shot of vitamin k soon after they are born. if you take blood thinners, you need to be careful about how much vitamin k you get. you also need to be careful about taking vitamin e supplements. vitamin e can interfere with how vitamin k works in your body. ask your health care provider for recommendations about these vitamins. there are different types of vitamin k. most people get vitamin k from plants such as green vegetables, and dark berries. bacteria in your intestines also produce small amounts of another type of vitamin k.

MalaCards based summary: Vitamin K Deficiency Hemorrhagic Disease, also known as vitamin k deficiency, is related to factor x deficiency and hereditary combined deficiency of vitamin k-dependent clotting factors. An important gene associated with Vitamin K Deficiency Hemorrhagic Disease is F2 (Coagulation Factor II, Thrombin), and among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2 and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include bone, and related mouse phenotypes are cardiovascular system and homeostasis/metabolism.

Related Diseases for Vitamin K Deficiency Hemorrhagic Disease

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Diseases related to Vitamin K Deficiency Hemorrhagic Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1factor x deficiency31.1F2, F3
2hereditary combined deficiency of vitamin k-dependent clotting factors12.6
3vitamin k-dependent clotting factors, combined deficiency of, 112.0
4vitamin k-dependent clotting factors, combined deficiency of, 212.0
5congenital disorder of glycosylation, type iil10.5
6chondrodysplasia punctata, x-linked dominant10.5
7t cell deficiency10.3AFP, F2
8central nervous system osteosarcoma10.3F2, F3
9esophagus melanoma10.3F2, F3
10epiglottitis10.3F2, F3
11cyclothymic disorder10.3F2, F3
12fowler's syndrome10.3F2, F3
13heart cancer10.3AFP, F2
14von willibrand disease, type 310.3F2, F3
15vaginal villous adenoma10.3F2, F3
16cavernous hemangioma of colon10.3F2, F3
17silo filler's disease10.3F2, F3
18herpes gestationis10.3F2, F3
19acrodermatitis10.3AFP, F2
20acquired thrombocytopenia10.3F2, F3
21abducens nerve neoplasm10.3F2, F3
22hypertrichosis10.3F2, F3
23splenic abscess10.3F2, F3
24skull base meningioma10.3F2, F3
25granulomatous hepatitis10.3F2, F3
26facioscapulohumeral muscular dystrophy 110.3F2, F3
27pre-malignant neoplasm10.3F2, F3
28kidney sarcoma10.3F2, F3
29trichostrongyloidiasis10.3AFP, F2
30nephropathia epidemica10.3F2, F3
31osteopetrosis10.3BGLAP, F2
32blood platelet disease10.3F2, F3
33meniere's disease10.3F2, F3
34vertebral artery insufficiency10.2F2, F3
35acantholytic squamous cell skin carcinoma10.2AFP, F2
36tricuspid valve disease10.2F2, F3
37thrombocytopenia cerebellar hypoplasia short stature10.2F2, F3
38factor v deficiency10.2F2, F3
39thrombophilia, x-linked, due to factor ix defect10.2F2, F3
40tall stature-scoliosis-macrodactyly of the great toes syndrome10.2F2, PROS1
41spinocerebellar ataxia 2710.2F2, F3
42pericardial mesothelioma10.2F2, PROS1
43thrombophilia due to activated protein c resistance10.2F2, F3
44capillariasis10.2F2, F3
45agammaglobulinemia x-linked type 210.2F2, F3
46van maldergem syndrome 210.2F2, F3
47stickler syndrome col2a110.2F2, F3
48hypermobility of coccyx10.2F2, F3
49interstitial cystitis10.2AFP, F3
50dentin dysplasia10.1F2, F3

Graphical network of the top 20 diseases related to Vitamin K Deficiency Hemorrhagic Disease:



Diseases related to vitamin k deficiency hemorrhagic disease

Symptoms for Vitamin K Deficiency Hemorrhagic Disease

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Drugs & Therapeutics for Vitamin K Deficiency Hemorrhagic Disease

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Vitamin K Deficiency Hemorrhagic Disease


Cochrane evidence based reviews: vitamin k deficiency

Genetic Tests for Vitamin K Deficiency Hemorrhagic Disease

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Anatomical Context for Vitamin K Deficiency Hemorrhagic Disease

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MalaCards organs/tissues related to Vitamin K Deficiency Hemorrhagic Disease:

33
Bone

Animal Models for Vitamin K Deficiency Hemorrhagic Disease or affiliated genes

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MGI Mouse Phenotypes related to Vitamin K Deficiency Hemorrhagic Disease:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053856.9F2, F3, GGCX, MGP, PROS1, VKORC1
2MP:00053766.8AFP, F2, F3, GGCX, MGP, PROS1
3MP:00107686.7AFP, F2, F3, GGCX, MGP, PROS1

Publications for Vitamin K Deficiency Hemorrhagic Disease

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Variations for Vitamin K Deficiency Hemorrhagic Disease

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Expression for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

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Search GEO for disease gene expression data for Vitamin K Deficiency Hemorrhagic Disease.

Pathways for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

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Pathways related to Vitamin K Deficiency Hemorrhagic Disease according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7BGLAP, MGP
29.7AFP, F2
3
Show member pathways
9.1GGCX, VKORC1
4
Show member pathways
9.0F2, F3, PROS1
5
Show member pathways
9.0F2, F3, PROS1
6
Show member pathways
9.0F2, F3, PROS1
7
Show member pathways
8.3BGLAP, F2, GGCX, PROS1
87.4BGLAP, F2, GGCX, MGP, PROS1, VKORC1

GO Terms for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

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Biological processes related to Vitamin K Deficiency Hemorrhagic Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to mechanical stimulusGO:000961210.0BGLAP, F3
2response to woundingGO:00096119.8F2, F3
3peptidyl-glutamic acid carboxylationGO:00171878.6F2, GGCX, PROS1, VKORC1
4post-translational protein modificationGO:00436878.5GGCX, PROS1, VKORC1

Sources for Vitamin K Deficiency Hemorrhagic Disease

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet