MCID: VTM001
MIFTS: 31

Vitamin K Deficiency Hemorrhagic Disease malady

Category: Metabolic diseases

Aliases & Classifications for Vitamin K Deficiency Hemorrhagic Disease

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Aliases & Descriptions for Vitamin K Deficiency Hemorrhagic Disease:

Name: Vitamin K Deficiency Hemorrhagic Disease 10 12
Vitamin K Deficiency 10 47 36 65
 
Deficiency of Vitamin K 10
Vitamin K 35

Classifications:



External Ids:

Disease Ontology10 DOID:11249
ICD1027 E56.1
SNOMED-CT59 124892003, 52675005
ICD9CM29 269.0
MeSH36 D014813
UMLS65 C0042880

Summaries for Vitamin K Deficiency Hemorrhagic Disease

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MedlinePlus:35 Vitamins are substances that your body needs to grow and develop normally. vitamin k helps your body by making proteins for healthy bones and tissues. it also makes proteins for blood clotting. if you don't have enough vitamin k, you may bleed too much. newborns have very little vitamin k. they usually get a shot of vitamin k soon after they are born. if you take blood thinners, you need to be careful about how much vitamin k you get. you also need to be careful about taking vitamin e supplements. vitamin e can interfere with how vitamin k works in your body. ask your health care provider for recommendations about these vitamins. there are different types of vitamin k. most people get vitamin k from plants such as green vegetables, and dark berries. bacteria in your intestines also produce small amounts of another type of vitamin k.

MalaCards based summary: Vitamin K Deficiency Hemorrhagic Disease, also known as vitamin k deficiency, is related to factor x deficiency and hereditary combined deficiency of vitamin k-dependent clotting factors. An important gene associated with Vitamin K Deficiency Hemorrhagic Disease is F2 (Coagulation Factor II, Thrombin), and among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2 and FOXA2 and FOXA3 transcription factor networks. Affiliated tissues include bone, spinal cord and kidney, and related mouse phenotypes are cardiovascular system and homeostasis/metabolism.

Related Diseases for Vitamin K Deficiency Hemorrhagic Disease

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Diseases related to Vitamin K Deficiency Hemorrhagic Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 69)
idRelated DiseaseScoreTop Affiliating Genes
1factor x deficiency30.7F2, F3
2hereditary combined deficiency of vitamin k-dependent clotting factors12.3
3vitamin k-dependent clotting factors, combined deficiency of, 111.6
4vitamin k-dependent clotting factors, combined deficiency of, 211.6
5t cell deficiency10.5AFP, F2
6central nervous system osteosarcoma10.4F2, F3
7esophagus melanoma10.4F2, F3
8epiglottitis10.4F2, F3
9cyclothymic disorder10.4F2, F3
10fowler's syndrome10.4F2, F3
11heart cancer10.4AFP, F2
12von willibrand disease, type 310.4F2, F3
13vaginal villous adenoma10.4F2, F3
14cavernous hemangioma of colon10.4F2, F3
15silo filler's disease10.4F2, F3
16herpes gestationis10.4F2, F3
17acrodermatitis10.4AFP, F2
18acquired thrombocytopenia10.4F2, F3
19abducens nerve neoplasm10.4F2, F3
20hypertrichosis10.4F2, F3
21splenic abscess10.4F2, F3
22skull base meningioma10.4F2, F3
23granulomatous hepatitis10.4F2, F3
24facioscapulohumeral muscular dystrophy 110.4F2, F3
25pre-malignant neoplasm10.4F2, F3
26kidney sarcoma10.4F2, F3
27trichostrongyloidiasis10.4AFP, F2
28nephropathia epidemica10.4F2, F3
29osteopetrosis10.4BGLAP, F2
30blood platelet disease10.4F2, F3
31meniere's disease10.4F2, F3
32vertebral artery insufficiency10.4F2, F3
33acantholytic squamous cell skin carcinoma10.4AFP, F2
34tricuspid valve disease10.4F2, F3
35thrombocytopenia cerebellar hypoplasia short stature10.4F2, F3
36factor v deficiency10.3F2, F3
37thrombophilia, x-linked, due to factor ix defect10.3F2, F3
38tall stature-scoliosis-macrodactyly of the great toes syndrome10.3F2, PROS1
39spinocerebellar ataxia 2710.3F2, F3
40pericardial mesothelioma10.3F2, PROS1
41thrombophilia due to activated protein c resistance10.3F2, F3
42capillariasis10.3F2, F3
43agammaglobulinemia x-linked type 210.3F2, F3
44van maldergem syndrome 210.3F2, F3
45stickler syndrome col2a110.3F2, F3
46hypermobility of coccyx10.3F2, F3
47interstitial cystitis10.3AFP, F3
48dentin dysplasia10.2F2, F3
49pregnancy loss, recurrent 210.2F2, F3
50postpartum depression10.2F2, F3

Comorbidity relations with Vitamin K Deficiency Hemorrhagic Disease via Phenotypic Disease Network (PDN):


Familial Atrial FibrillationHeart Disease
Acute Cystitis

Graphical network of the top 20 diseases related to Vitamin K Deficiency Hemorrhagic Disease:



Diseases related to vitamin k deficiency hemorrhagic disease

Symptoms for Vitamin K Deficiency Hemorrhagic Disease

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Drugs & Therapeutics for Vitamin K Deficiency Hemorrhagic Disease

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Vitamin K Deficiency Hemorrhagic Disease


Cochrane evidence based reviews: vitamin k deficiency

Genetic Tests for Vitamin K Deficiency Hemorrhagic Disease

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Anatomical Context for Vitamin K Deficiency Hemorrhagic Disease

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MalaCards organs/tissues related to Vitamin K Deficiency Hemorrhagic Disease:

33
Bone, Spinal cord, Kidney, Breast, Endothelial, T cells, Skin

Animal Models for Vitamin K Deficiency Hemorrhagic Disease or affiliated genes

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MGI Mouse Phenotypes related to Vitamin K Deficiency Hemorrhagic Disease:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053856.9F2, F3, GGCX, MGP, PROS1, VKORC1
2MP:00053766.8AFP, F2, F3, GGCX, MGP, PROS1
3MP:00107686.7AFP, F2, F3, GGCX, MGP, PROS1

Publications for Vitamin K Deficiency Hemorrhagic Disease

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Variations for Vitamin K Deficiency Hemorrhagic Disease

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Expression for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

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Search GEO for disease gene expression data for Vitamin K Deficiency Hemorrhagic Disease.

Pathways for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

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Pathways related to Vitamin K Deficiency Hemorrhagic Disease according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7BGLAP, MGP
29.7AFP, F2
3
Show member pathways
9.1GGCX, VKORC1
4
Show member pathways
9.0F2, F3, PROS1
5
Show member pathways
9.0F2, F3, PROS1
6
Show member pathways
9.0F2, F3, PROS1
7
Show member pathways
8.3BGLAP, F2, GGCX, PROS1
87.4BGLAP, F2, GGCX, MGP, PROS1, VKORC1

GO Terms for genes affiliated with Vitamin K Deficiency Hemorrhagic Disease

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Biological processes related to Vitamin K Deficiency Hemorrhagic Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to mechanical stimulusGO:000961210.0BGLAP, F3
2response to woundingGO:00096119.8F2, F3
3peptidyl-glutamic acid carboxylationGO:00171878.6F2, GGCX, PROS1, VKORC1
4post-translational protein modificationGO:00436878.5GGCX, PROS1, VKORC1

Sources for Vitamin K Deficiency Hemorrhagic Disease

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet