MCID: VTM003
MIFTS: 20

Vitamin Metabolic Disorder

Categories: Metabolic diseases

Aliases & Classifications for Vitamin Metabolic Disorder

MalaCards integrated aliases for Vitamin Metabolic Disorder:

Name: Vitamin Metabolic Disorder 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:0050718

Summaries for Vitamin Metabolic Disorder

Disease Ontology : 12 An inherited metabolic disorder resulting from a deficiency in vitamin or vitamin cofactor transport or metabolism.

MalaCards based summary : Vitamin Metabolic Disorder is related to vitamin b12 deficiency and vitamin e, familial isolated deficiency of. An important gene associated with Vitamin Metabolic Disorder is GIF (Gastric Intrinsic Factor), and among its related pathways/superpathways are Metabolism and HIV Life Cycle.

Related Diseases for Vitamin Metabolic Disorder

Graphical network of the top 20 diseases related to Vitamin Metabolic Disorder:



Diseases related to Vitamin Metabolic Disorder

Symptoms & Phenotypes for Vitamin Metabolic Disorder

Drugs & Therapeutics for Vitamin Metabolic Disorder

Search Clinical Trials , NIH Clinical Center for Vitamin Metabolic Disorder

Genetic Tests for Vitamin Metabolic Disorder

Anatomical Context for Vitamin Metabolic Disorder

Publications for Vitamin Metabolic Disorder

Variations for Vitamin Metabolic Disorder

Expression for Vitamin Metabolic Disorder

Search GEO for disease gene expression data for Vitamin Metabolic Disorder.

Pathways for Vitamin Metabolic Disorder

Pathways related to Vitamin Metabolic Disorder according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.73 AMN CD320 CUBN GIF MMADHC MTHFR
2
Show member pathways
13.41 AMN CD320 CUBN GIF MMADHC MTR
3
Show member pathways
12.46 AMN CD320 CUBN GIF MMADHC MTHFR
4
Show member pathways
12.14 CUBN GIF MTHFR MTR MUT TCN1
5
Show member pathways
11.98 MTHFR MTR MUT
6
Show member pathways
11.78 MTHFR MTR TCN2
7
Show member pathways
11.21 AMN CD320 CUBN GIF MMADHC MTR
8 10.95 AMN CD320 CUBN GIF MMADHC MTR
9 10.92 CUBN GIF TCN2
10
Show member pathways
10.34 AMN CUBN GIF

GO Terms for Vitamin Metabolic Disorder

Cellular components related to Vitamin Metabolic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 9.54 AMN CUBN GIF
2 clathrin-coated pit GO:0005905 9.4 AMN CUBN
3 endosome membrane GO:0010008 9.33 AMN CD320 CUBN
4 endocytic vesicle GO:0030139 9.32 AMN CUBN
5 brush border membrane GO:0031526 9.26 AMN CUBN
6 endosome GO:0005768 9.26 AMN CUBN GIF TCN2
7 lysosomal lumen GO:0043202 8.8 CUBN GIF TCN2

Biological processes related to Vitamin Metabolic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transport GO:0006810 9.85 AMN CUBN GIF TCN1 TCN2 TTPA
2 cobalamin metabolic process GO:0009235 9.61 AMN CD320 CUBN GIF MMADHC MTR
3 cobalt ion transport GO:0006824 9.33 GIF TCN1 TCN2
4 high-density lipoprotein particle clearance GO:0034384 9.32 AMN CUBN
5 homocysteine metabolic process GO:0050667 9.26 MTHFR MUT
6 cobalamin transport GO:0015889 9.1 AMN CD320 CUBN GIF TCN1 TCN2

Molecular functions related to Vitamin Metabolic Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cobalamin binding GO:0031419 9.17 CD320 CUBN GIF MTR MUT TCN1
2 modified amino acid binding GO:0072341 8.96 MTHFR MUT

Sources for Vitamin Metabolic Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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