MCID: VTR013
MIFTS: 50

Vitreoretinopathy, Neovascular Inflammatory malady

Categories: Genetic diseases, Eye diseases, Rare diseases

Aliases & Classifications for Vitreoretinopathy, Neovascular Inflammatory

About this section

Aliases & Descriptions for Vitreoretinopathy, Neovascular Inflammatory:

Name: Vitreoretinopathy, Neovascular Inflammatory 52 24 70 27 12
Proliferative Vitreoretinopathy 11 24 70 13 68
Adniv 54 70
Vrni 24 70
Pvr 24 70
Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy 54
 
Neovascular Inflammatory Vitreoretinopathy Autosomal Dominant 70
Vitreoretinopathy, Proliferative 39
Proliferative Vitreo-Retinopathy 68
Vitreoretinopathy Proliferative 50
Retinitis Proliferans 11

Characteristics:

Orphanet epidemiological data:

54
adniv:
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: All ages

HPO:

64
vitreoretinopathy, neovascular inflammatory:
Inheritance: autosomal dominant inheritance

Classifications:

Orphanet: 54 
Rare eye diseases


External Ids:

OMIM52 193235
Disease Ontology11 DOID:9719
MeSH39 D018630
Orphanet54 ORPHA329211
ICD10 via Orphanet31 H35.2
MedGen37 C1860404

Summaries for Vitreoretinopathy, Neovascular Inflammatory

About this section
UniProtKB/Swiss-Prot:70 Vitreoretinopathy, neovascular inflammatory: An autoimmune condition of the eye that sequentially mimics uveitis, retinitis pigmentosa, and proliferative diabetic retinopathy as it progresses to complete blindness. Patients present during the second or third decade of life with posterior uveitis and reduction of the electroretinogram b-wave. They become more symptomatic when cataracts, cystoid macular edema, and disk edema diminish visual acuity during the second stage. Severe vision loss begins during the third stage when proliferative retinal neovascularization and epiretinal membranes appear. There is an ongoing pigmentary retinal degeneration and peripheral visual field loss during all stages. In the fourth stage, proliferative vitreoretinopathy causes tractional retinal detachments at the macula and vitreous base. The fifth or end-stage disease is marked by phthisis.

MalaCards based summary: Vitreoretinopathy, Neovascular Inflammatory, also known as proliferative vitreoretinopathy, is related to poliomyelitis and paralytic poliomyelitis, and has symptoms including abnormal electroretinogram, retinal detachment and uveitis. An important gene associated with Vitreoretinopathy, Neovascular Inflammatory is CAPN5 (Calpain 5), and among its related pathways are IL-4 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. Affiliated tissues include eye and retina, and related mouse phenotypes are muscle and respiratory system.

OMIM:52 Autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV) is a blinding disorder that shares some clinical... (193235) more...

Related Diseases for Vitreoretinopathy, Neovascular Inflammatory

About this section

Diseases related to Vitreoretinopathy, Neovascular Inflammatory via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 83)
idRelated DiseaseScoreTop Affiliating Genes
1poliomyelitis11.0
2paralytic poliomyelitis10.9
3bile acid synthesis defect, congenital, 210.8
4pericardium disease10.8
5heart conduction disease10.8
6cardiac tamponade10.8
7pericardial effusion10.8
8enterocele10.8
9prolapse of female genital organ10.8
10basilar artery insufficiency10.8
11ovarian cystic teratoma10.8
12urethral diverticulum10.8
13retinitis10.8
14retinal detachment10.7
15diamond-blackfan anemia10.5TGFB1, TGFB2
16lymphogranuloma venereum10.5CTGF, TGFB1
17thrombocytosis10.5FGF2, TGFB1
18pericardial mesothelioma10.5FGF2, TGFB1
19hypohidrosis10.5CTGF, TGFB1
20scrotum paget's disease10.5FGF2, TGFB1
21stomatitis10.5CTGF, TGFB1
22colorectal adenoma10.5FGF2, HGF
23fibrosclerosis of breast10.4TGFB1, TGFB2
24acromicric dysplasia10.4CTGF, TGFB1, TGFB2
25fibromatosis, gingival, 110.4HGF, TGFB1
26strawberry gallbladder10.4TGFB1, TGFB2
27citrullinemia, adult-onset type ii10.3CTGF, FGF2, TGFB2
28degeneration of macula and posterior pole10.3FGF2, GFAP, TGFB1
29vibrio vulnificus infection10.3CCL2, TGFB1
30gallbladder squamous cell carcinoma10.3HGF, MET
31medullomyoblastoma10.2HGF, MET
32endotheliitis10.2
33esophagus verrucous carcinoma10.2FGF2, HGF
34twin-to-twin transfusion syndrome10.2CCL2, TGFB1, TGFB2
35hypopigmentation of eyelid10.2CCL2, CTGF, TGFB1
36benign neonatal seizures10.2CCL2, CTGF, TGFB1
37benign struma ovarii10.2CCL2, CTGF, TGFB1
38drachtman weinblatt sitarz syndrome10.2HGF, MET
39perrault syndrome10.2CCL2, CTGF, TGFB1
40nonspecific interstitial pneumonia10.2CCL2, CTGF, TGFB1
41renal oncocytoma10.1CCL2, CTGF, TGFB1
42hereditary renal cell carcinoma10.1CAPN5, CCL2
43gasserian ganglion meningioma10.1CCL2, TGFB2
44prostatic urethral cancer10.1HGF, MET
4546 xy gonadal dysgenesis10.0TGFB1, TGFB2, TIMP1
46salt and pepper syndrome10.0CTGF, TGFB1, TIMP1
47echinococcosis10.0CTGF, TGFB1, TIMP1
48nephropathy familial with hyperuricemia10.0CTGF, TGFB1, TIMP1
49paranasal sinus sarcoma10.0CTGF, TGFB1, TIMP1
50angiomyoma10.0FGF2, SPARC

Graphical network of the top 20 diseases related to Vitreoretinopathy, Neovascular Inflammatory:



Diseases related to vitreoretinopathy, neovascular inflammatory

Symptoms & Phenotypes for Vitreoretinopathy, Neovascular Inflammatory

About this section

Symptoms by clinical synopsis from OMIM:

193235

Clinical features from OMIM:

193235

Human phenotypes related to Vitreoretinopathy, Neovascular Inflammatory:

 64 (show all 7)
id Description HPO Frequency HPO Source Accession
1 abnormal electroretinogram64 HP:0000512
2 retinal detachment64 HP:0000541
3 uveitis64 HP:0000554
4 blindness64 HP:0000618
5 large hyperpigmented retinal spots64 HP:0007658
6 posterior retinal neovascularization64 HP:0007778
7 vitreous hemorrhage64 HP:0007902

UMLS symptoms related to Vitreoretinopathy, Neovascular Inflammatory:


eye manifestations

MGI Mouse Phenotypes related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.1ADM, FGF2, GFAP, MET, TGFB1, TGFB2
2MP:00053888.8ADM, CTGF, MET, TGFB1, TGFB2, TIMP1
3MP:00053858.0ADM, CTGF, FGF2, GFAP, HGF, MET
4MP:00053917.7CTGF, FGF2, GFAP, MET, SPARC, TGFB1
5MP:00107687.7ADM, CAPN5, CTGF, FGF2, GFAP, HGF
6MP:00053787.6CAPN5, CTGF, GFAP, HGF, MET, SPARC
7MP:00053877.4ADM, CAPN5, CCL2, GFAP, MET, SPARC
8MP:00053977.4ADM, FGF1, FGF2, HGF, SPARC, TGFB1
9MP:00053766.6ADM, CTGF, FGF1, FGF2, GFAP, MET

Drugs & Therapeutics for Vitreoretinopathy, Neovascular Inflammatory

About this section

Drugs for Vitreoretinopathy, Neovascular Inflammatory (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 45)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Triamcinoloneapproved, vet_approvedPhase 4, Phase 3482124-94-731307
Synonyms:
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
124-94-7
4-08-00-03629 (Beilstein Handbook Reference)
83474-03-7
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy
9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-16alpha-hydroxyprednisolone
9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-16α-hydroxyprednisolone
AC-2072
AC1L1LDH
AC1Q5HJC
Adcortyl
Aristocort
Aristocort A
Aristocort Tablets
Aristogel
Aristospan
Azmacort
BPBio1_000154
BRD-K77554836-001-03-3
BRN 2341955
BSPBio_000140
Bio-0662
C21H27FO6
CHEMBL1451
CID31307
CL 19823
Celeste
Cinolone
Cinolone-T
D00385
D014221
DB00620
Delphicort
EINECS 204-718-7
EU-0101179
Fluoxiprednisolone
Fluoxyprednisolone
Flutex
Fougera
HMS1568G22
HMS2090D12
HSDB 3194
Kenacort
Kenacort (TN)
Kenacort-A
Kenacort-AG
Kenacort-Ag
Kenalog
Kenalog in Orabase
Kenalog-10
Kenalog-40
Kenalog-H
LS-698
Ledercort
Lopac0_001179
 
MLS000028542
MLS001066543
MLS002695935
MolPort-002-528-981
Mycolog
NCGC00021580-03
NCGC00021580-04
NCGC00021580-05
NCGC00021580-06
NCGC00021580-07
NCI60_000750
NSC 13397
NSC13397
Nasacort
Nasacort Aq
Nasacort Hfa
Omcilon
Omicilon
Oracort
Oralone
Orion
Polcortolon
Pregna-1,4-diene-3,20-dio
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI)
Prestwick0_000120
Prestwick1_000120
Prestwick2_000120
Prestwick3_000120
Prestwick_438
Rodinolone
S1933_Selleck
SK-Triamcinolone
SMP1_000300
SMR000058333
SPBio_002079
Sk-Triamcinolone
T6376_SIGMA
TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7))
Tiamcinolonum
Tiamcinolonum [INN-Latin]
Tri-Nasal
Triacet
Triacort
Triam-Tablinen
Triamcet
Triamcinalone
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolona [INN-Spanish]
Triamcinolone (JP15/USP/INN)
Triamcinolone [USAN:INN:BAN:JAN]
Triamcinolone acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Triamcinolonum
Triamcinolonum [INN]
Triatex
Tricortale
Triderm
Trilone
Tristoject
Trymex
UNII-1ZK20VI6TY
Vetalog
Volon
Volon A
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ
ZINC03882036
droxypregna-1,4-diene-3,20-dione
ione
nchembio.2007.53-comp7
triamcinolone
2
IsotretinoinapprovedPhase 41184759-48-25538, 5282379
Synonyms:
(13-cis)-Retinoate
(13-cis)-Retinoic acid
(13cis)-retinoic acid
(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
(2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
(7E,9E,11E,13Z)-retinoic acid
(7e,9e,11e,13Z)-Retinoic acid
13 Cis-Retinoic Acid
13 cis retinoic acid
13-RA
13-cis RA
13-cis retinoic acid
13-cis-Retinoate
13-cis-Retinoic acid
13-cis-Vitamin A acid
13-cis-Vitamin a acid
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-trans-6-trans-8-trans-nonatetraenoic acid
4-09-00-02388 (Beilstein Handbook Reference)
4759-48-2
97950-17-9
AC-15388
AC1NQZZ4
Accutane
Accutane (TN)
Ambap302-79-4
Amnesteem
BML2-E07
BPBio1_000080
BRD-K76723084-001-05-9
BRN 1885770
BSPBio_000072
BSPBio_001331
BSPBio_003345
CCRIS 4286
CHEBI:6067
CHEMBL547
CID5282379
CIP-Isotretinoin
CPD000471891
Claravis
D00348
D015474
EINECS 225-296-0
EU-0101081
HMS1361C13
HMS1568D14
HMS1791C13
HMS1921D08
HMS1989C13
HMS2092N07
HSDB 3929
IDI1_033801
Isotane
Isotretinoin
Isotretinoin (USP)
Isotretinoin Retinoic acid
 
Isotretinoin Zinc Salt, 13 cis Isomer
Isotretinoin Zinc Salt, 13-cis-Isomer
Isotretinoin [USAN:BAN:INN]
Isotretinoin [USAN:INN:BAN]
Isotretinoina
Isotretinoine
Isotretinoine [INN-French]
Isotretinoino
Isotretinoino [INN-Spanish]
Isotretinoinum
Isotretinoinum [INN-Latin]
Isotrex
LMPR01090021
LS-143465
Lopac0_001081
MLS001074662
MolPort-003-666-394
NCGC00094358-01
NCGC00094358-02
NCGC00094358-03
NCGC00094358-04
NCGC00094358-05
NCGC00094358-06
NCGC00094358-07
NCGC00094358-08
NCGC00094358-09
NCGC00094358-13
Neovitamin A acid
Neovitamin a acid
Prestwick2_000256
Prestwick3_000256
Prestwick_642
R 3255
R3255_SIGMA
Retinoate
Retinoic acid
Ro 4 3780
Ro 4-3780
Ro 43780
Ro-4-3780
Ro-43780
Roaccutan
Roaccutane
Roacutan
SAM002548955
SMR000471891
SPECTRUM1502013
Sotret
Sotret (TN)
Spectrum5_001795
Spectrum5_001937
Teriosal
UNII-EH28UP18IF
cis-RA
cis-Retinoate
cis-Retinoic acid
isotretinoino
3
Bupivacaineapproved, investigationalPhase 411312180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
4Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 312767
5Peripheral Nervous System AgentsPhase 4, Phase 322776
6Triamcinolone diacetatePhase 4, Phase 3482
7Dermatologic AgentsPhase 45674
8Triamcinolone hexacetonidePhase 4, Phase 3482
9HormonesPhase 4, Phase 313979
10triamcinolone acetonidePhase 4, Phase 3482
11glucocorticoidsPhase 4, Phase 34920
12Anti-Inflammatory AgentsPhase 4, Phase 310355
13Hormone AntagonistsPhase 4, Phase 312778
14AnestheticsPhase 49001
15Anesthetics, LocalPhase 43272
16Immunosuppressive AgentsPhase 4, Phase 312770
17Central Nervous System DepressantsPhase 412806
18
FluorouracilapprovedPhase 3179151-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen
19
Heparinapproved, investigationalPhase 38129005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Unfractionated heparin
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
20
ColchicineapprovedPhase 311164-86-86167, 2833
Synonyms:
(S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
30512-31-3
5843-86-7
64-86-8
7-alpha-H-Colchicine
7.alpha.H-Colchicine
7alphaH-Colchicine
AC1L1LXO
ACon1_000353
AI3-31149
AKOS001582887
BB_NC-0737
BPBio1_000535
BRD-K00259736-001-06-5
BSPBio_000485
BSPBio_002083
Benzo(a)heptalen-9(5H)-one
C 9754
C07592
C22H25NO6
C3915_SIGMA
C9754_SIGMA
CCRIS 691
CHEBI:27882
CHEMBL107
CID6167
CPD-9785
Colchicin
Colchicin [German]
Colchicina
Colchicina [Italian]
Colchicine (JP15/USP)
Colchicine (TN)
Colchicine [JAN]
Colchicine, (+-)-Isomer
Colchicine, (R)-Isomer
Colchicine, Colchicum autumnale
Colchicinum
Colchineos
Colchisol
Colchysat
Colcin
Colcrys
Colsaloid
Colstat
Condylon
D003078
D00570
DB01394
DB08117
DivK1c_000753
EINECS 200-598-5
EU-0100310
Goutnil
HMS1569I07
HMS1920A08
HMS2091G16
HMS502F15
HSDB 3044
IDI1_000753
KBio1_000753
KBio2_001322
KBio2_003890
 
KBio2_006458
KBio3_001303
KBioGR_000856
KBioSS_001322
Kolkicin
LOC
LS-279
Lopac0_000310
MEGxp0_001879
MLS001055448
MLS001055448-02
MLS001304089
MLS002153786
MPC-004
MolPort-001-742-594
N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)- acetamide
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[.alpha.]heptalen-7-yl)-acetamide
N-Acetyl trimethylcolchicinic acid methylether
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide
NCGC00025125-01
NCGC00025125-02
NCGC00025125-03
NCGC00025125-04
NCGC00025125-05
NCGC00025125-06
NCGC00025125-07
NCGC00025125-11
NCGC00169157-01
NCGC00169157-02
NCGC00169157-03
NCI60_041659
NChemBio.2007.10-comp20
NINDS_000753
NSC 757
NSC757
Prestwick0_000363
Prestwick1_000363
Prestwick2_000363
Prestwick3_000363
Prestwick_695
S2284_Selleck
SDCCGMLS-0066633.P001
SMR000058323
SPBio_000289
SPBio_002406
SPECTRUM1500205
Spectrum2_000075
Spectrum3_000362
Spectrum4_000298
Spectrum5_000787
Spectrum_000842
Tocris-1364
UNII-SML2Y3J35T
UPCMLD-DP065
UPCMLD-DP065:001
WLN: L B677 MV&T&J CO1 DO1 EO1 JMV1 NO1
ZINC00621853
binds to tubulin
colchicine
inhibits microtubular assembly
nchembio853-comp2
spindle poison
21
DalteparinapprovedPhase 33039041-08-1
Synonyms:
Daltepariininatrium
Dalteparin Sodyum
Dalteparin sodium
Dalteparin sodná sůl
Dalteparin-nátrium
Dalteparina sódica
 
Dalteparinnatrium
Dalteparino natrio druska
Dalteparinum Natricum
Dalteparyna sodowa
Daltéparine sodique
Heparin Fragment KABI 2165
Tedelparin
22
Dexamethasoneapproved, investigational, vet_approvedPhase 3208450-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
23
Vitamin Capproved, nutraceuticalPhase 351450-81-75785, 54670067
Synonyms:
(+)-Sodium L-ascorbate
(+)-ascorbate
(+)-ascorbic acid
(2R)-2-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-furan-3-one
(2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
129940-97-2
134-03-2 (monosodium salt)
14536-17-5
154170-90-8
2-(1,2-Dihydroxyethyl)-4,5-dihydroxyfuran-3-one
255564_SIAL
259133-78-3
3-Keto-L-gulofuranolactone
3-Oxo-L-gulofuranolactone
3-Oxo-L-gulofuranolactone (enol form)
30208-61-8
33034_RIEDEL
33034_SIAL
47863_SUPELCO
47A605F0-4187-47A8-B0CE-F9E7DA1B0076
50-81-7
50976-75-5
56172-55-5
56533-05-2
57304-74-2
57606-40-3
623158-95-2
6730-29-6
882690-91-7
884381-69-5
885512-24-3
88845-26-5
89924-69-6
95209_FLUKA
95209_SIGMA
95210_FLUKA
95210_SIAL
95212_FLUKA
A0278_SIGMA
A0537
A2174_SIGMA
A2218_SIGMA
A2343_SIGMA
A4403_SIGMA
A4544_SIGMA
A5960_SIGMA
A7506_SIGMA
A92902_ALDRICH
A92902_SIAL
AA
AB00376923
AB1002440
AC1L1L4T
AC1Q77S6
AR-1J3435
Acid Ascorbic
Acide ascorbique
Acide ascorbique [INN-French]
Acido ascorbico
Acido ascorbico [INN-Spanish]
Acidum ascorbicum
Acidum ascorbicum [INN-Latin]
Acidum ascorbinicum
Adenex
Allercorb
Ambap36431-82-0
Antiscorbic Vitamin
Antiscorbic vitamin
Antiscorbutic Vitamin
Antiscorbutic factor
Antiscorbutic vitamin
Arco-Cee
Arco-cee
Ascoltin
Ascoltin (TN)
Ascor-B.I.D.
Ascorb
Ascorbajen
Ascorbate
Ascorbic Acid
Ascorbic Acid, Monosodium Salt
Ascorbic acid
Ascorbic acid (JP15/USP/INN)
Ascorbic acid [BAN:INN:JAN]
Ascorbic acid [INN:BAN:JAN]
Ascorbicab
Ascorbicap
Ascorbicap (TN)
Ascorbicin
Ascorbin
Ascorbinsaeure
Ascorbinsäure
Ascorbutina
Ascorbyl radical
Ascorin
Ascorteal
Ascorvit
BPBio1_000363
BSPBio_000329
C-Level
C-Long
C-Quin
C-Span
C-Vimin
C00072
C6H8O6
CCRIS 57
CE-VI-Sol
CHEBI:29073
CHEMBL196
CID5785
Cantan
Cantaxin
Caswell No. 061B
Catavin C
Ce Lent
Ce lent
Ce-Mi-Lin
Ce-mi-lin
Ce-vi-sol
Cebicure
Cebid
Cebion
Cebione
Cecon
Cee-Caps TD
Cee-Caps Td
Cee-Vite
Cee-caps TD
Cee-vite
Cegiolan
Ceglion
Ceklin
Celaskon
Celin
Cell C
Cemagyl
Cemill
Cenetone
Cenolate
Cereon
Cergona
Cescorbat
Cetamid
Cetane
Cetane-Caps TC
Cetane-Caps TD
Cetane-Caps Tc
Cetane-Caps Td
Cetane-caps TC
Cetane-caps TD
Cetebe
 
Cetemican
Cevalin
Cevatine
Cevex
Cevi-Bid
Cevi-bid
Cevimin
Cevital
Cevitamate
Cevitamic Acid
Cevitamic acid
Cevitamin
Cevitan
Cevitex
Cewin
Chewcee
Ciamin
Cipca
Citriscorb
Citrovit
Colascor
Concemin
Cortalex
D00018
DB00126
Davitamon C
Dora-C-500
Duoscorb
EINECS 200-066-2
FEMA No. 2109
Ferancee
Ferrous ascorbate
HSDB 818
HiCee
Hicee
Hybrin
IDO-C
Ido-C
Iron(II) ascorbate
Iron-ascorbic acid complexes
Juvamine
Kangbingfeng
Kyselina Askorbova
Kyselina askorbova
Kyselina askorbova [Czech]
L(+)-Ascorbate
L(+)-Ascorbic acid
L-(+)-Ascorbate
L-(+)-Ascorbic Acid
L-(+)-Ascorbic acid
L-(+)-ascorbic acid
L-3-Ketothreohexuronic acid lactone
L-3-ketothreohexuronic acid
L-Ascorbate
L-Ascorbic Acid
L-Ascorbic acid
L-Ascorbic acid, free radical form
L-Lyxoascorbate
L-Lyxoascorbic Acid
L-Lyxoascorbic acid
L-Threo-ascorbic acid
L-Threoascorbic acid
L-Xyloascorbate
L-Xyloascorbic Acid
L-Xyloascorbic acid
L-ascorbate
L-threo-Hex-2-enonic acid, gamma-lactone
L-threo-ascorbic acid
L-threo-hex-2-enono-1,4-lactone
LS-145
Laroscorbine
Lemascorb
Liqui-Cee
Liqui-cee
MLS002153776
Magnesium Ascorbicum
Magnorbin
Meri-C
Meri-c
MolPort-001-792-501
Monodehydroascorbic acid
NCGC00091517-01
NCGC00091517-02
NCGC00164357-01
NCI-C54808
NSC 33832
Natrascorb
Natrascorb injectable
Oral Vitamin C
Planavit C
Prestwick3_000325
Proscorbin
Redoxon
Ribena
Ronotec 100
Rontex 100
Roscorbic
Rovimix C
SMR001233160
Scorbacid
Scorbu C
Scorbu-C
Secorbate
Semidehydroascorbate
Sodascorbate
Sodium Ascorbate (Ascorbic Acid)
Stuartinic
Suncoat VC 40
Sunkist
Testascorbic
Tolfrinic
UNII-PQ6CK8PD0R
VASC
Vicelat
Vicin
Vicomin C
Viforcit
Viscorin
Viscorin 100M
Vitace
Vitacee
Vitacimin
Vitacin
Vitamin C
Vitamin- C
Vitamin-?C
Vitamisin
Vitascorbol
W210901_ALDRICH
Xitix
acide ascorbique
acidum ascorbicum
acidum ascorbinicum
antiscorbic vita min
ascor-b.i.d
ascorbate
ascorbic acid
bmse000182
cee-caps td
cevibid
component of Cortalex
component of E and C-Level
component of Endoglobin Forte
component of Ferancee
gamma-Lactone L-threo-Hex-2-enonate
gamma-Lactone L-threo-Hex-2-enonic acid
l-ascorbic acid
l-threo-hex-1-eofuranos-3-ulose
nchembio.174-comp5
nchembio.89-comp1
nchembio.92-comp2
nchembio821-comp9
roscorbi c
vitamin C
ácido ascórbico
24Fibrinolytic AgentsPhase 32317
25HIV Protease InhibitorsPhase 35319
26Dexamethasone acetatePhase 320841177-87-3
27
protease inhibitorsPhase 35320
Synonyms:
 
protease inhibitors
28Heparin, Low-Molecular-WeightPhase 3320
29Gastrointestinal AgentsPhase 38109
30Autonomic AgentsPhase 39774
31Antimitotic AgentsPhase 35498
32Dexamethasone 21-phosphatePhase 32084
33AnticoagulantsPhase 32516
34Antineoplastic Agents, HormonalPhase 35407
35AntiemeticsPhase 33888
36Antirheumatic AgentsPhase 310627
37Calcium, DietaryPhase 35525
38calcium heparinPhase 3812
39BB 1101Phase 32084
40Pharmaceutical SolutionsPhase 37793
41Antimetabolites, AntineoplasticPhase 37171
42AntimetabolitesPhase 311774
43
Bevacizumabapproved, investigationalPhase 21968216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
44Angiogenesis InhibitorsPhase 24143
45Angiogenesis Modulating AgentsPhase 24072

Interventional clinical trials:

(show all 19)
idNameStatusNCT IDPhase
1Isotretinoin for Proliferative VitreoretinopathyUnknown statusNCT01445028Phase 4
2Postoperative Pain Control Following Vitreoretinal SurgeryCompletedNCT01995045Phase 4
3Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR)Unknown statusNCT00370760Phase 3
4Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal DetachmentUnknown statusNCT00370201Phase 3
5The Effect of 5-FU and LMW Heparin on the Rate of Retinal Redetachment After Silicone Oil Removal in Cases of PVRUnknown statusNCT00371020Phase 3
6Comparison High-Density Silicone Oils in Retinal DetachmentUnknown statusNCT00403702Phase 2, Phase 3
7Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical TrialUnknown statusNCT00370279Phase 3
8Triamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative VitreoretinopathyCompletedNCT00373282Phase 3
9The Silicone StudyCompletedNCT00000140Phase 3
10Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment.RecruitingNCT02834559Phase 3
11Adjunctive Steroid Combination in Ocular Trauma (ASCOT) StudyRecruitingNCT02873026Phase 3
12Bevacizumab Against Recurrent Retinal DetachmentUnknown statusNCT02192970Phase 2
13Dacorin for Proliferative VitreoretinopathyCompletedNCT02865031Phase 1, Phase 2
14Eye Injections of Bevacizumab to See if Medication Helps to Lower Risk of Scar Tissue Development in the Retina and Repeated Retinal Detachment.Unknown statusNCT01860586
15Comparison of Two Techniques for Epiretinal or Internal Limiting Membrane PeelUnknown statusNCT00892619
16Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal DetachmentsCompletedNCT01255293
17Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery.RecruitingNCT01959568
18Optical Coherence Tomography - Rescan During Dissection of Macular MembranesNot yet recruitingNCT02748421
19Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment in Patients With Extended CriteriaNot yet recruitingNCT02871531

Search NIH Clinical Center for Vitreoretinopathy, Neovascular Inflammatory


Cochrane evidence based reviews: vitreoretinopathy, proliferative

Genetic Tests for Vitreoretinopathy, Neovascular Inflammatory

About this section

Genetic tests related to Vitreoretinopathy, Neovascular Inflammatory:

id Genetic test Affiliating Genes
1 Vitreoretinopathy, Neovascular Inflammatory27 24 CAPN5

Anatomical Context for Vitreoretinopathy, Neovascular Inflammatory

About this section

MalaCards organs/tissues related to Vitreoretinopathy, Neovascular Inflammatory:

36
Eye, Retina

Publications for Vitreoretinopathy, Neovascular Inflammatory

About this section

Variations for Vitreoretinopathy, Neovascular Inflammatory

About this section

UniProtKB/Swiss-Prot genetic disease variations for Vitreoretinopathy, Neovascular Inflammatory:

70
id Symbol AA change Variation ID SNP ID
1CAPN5p.Arg243LeuVAR_069277rs397514601
2CAPN5p.Leu244ProVAR_069278rs397514602

Clinvar genetic disease variations for Vitreoretinopathy, Neovascular Inflammatory:

5
id Gene Variation Type Significance SNP ID Assembly Location
1CAPN5NM_004055.4(CAPN5): c.728G> T (p.Arg243Leu)SNVPathogenicrs397514601GRCh37Chr 11, 76826469: 76826469
2CAPN5NM_004055.4(CAPN5): c.731T> C (p.Leu244Pro)SNVPathogenicrs397514602GRCh37Chr 11, 76826472: 76826472

Expression for genes affiliated with Vitreoretinopathy, Neovascular Inflammatory

About this section
Search GEO for disease gene expression data for Vitreoretinopathy, Neovascular Inflammatory.

Pathways for genes affiliated with Vitreoretinopathy, Neovascular Inflammatory

About this section

Pathways related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

(show all 43)
idSuper pathwaysScoreTop Affiliating Genes
19.9TGFB1, TGFB2
29.9TGFB1, TGFB2
39.6FGF2, TGFB1, TGFB2
49.6FGF2, TGFB1, TGFB2
5
Show member pathways
9.5TGFB1, TGFB2, VTN
6
Show member pathways
9.5FGF2, TGFB1, VTN
79.4CCL2, TGFB1, TGFB2
89.4CCL2, TGFB1, TGFB2
99.4CCL2, GFAP, TGFB1
109.4CCL2, TIMP1
119.3HGF, MET, TGFB1
129.1FGF1, FGF2, MET
139.1FGF1, FGF2, MET
149.1CTGF, FGF1, TGFB1, TGFB2
159.1FGF1, HGF, MET
169.1FGF1, FGF2, TGFB1, TGFB2
179.1SPARC, TGFB1, TGFB2
189.0FGF2, HGF, MET, TGFB1
199.0SPARC, TGFB1, VTN
20
Show member pathways
8.8FGF1, FGF2, HGF, MET
218.8FGF2, SPARC, TGFB1, TGFB2
228.7SPARC, TGFB1, TGFB2, VTN
238.7SPARC, TIMP1, VTN
248.6CCL2, HGF, MET, TGFB1, TGFB2
258.4FGF1, FGF2, HGF, MET, VTN
268.4FGF2, HGF, MET, TGFB1, TGFB2, VTN
278.2FGF1, FGF2, HGF, MET, TGFB1, TGFB2
287.8CTGF, FGF1, FGF2, HGF, TGFB1, TGFB2
29
Show member pathways
7.7CCL2, FGF1, FGF2, HGF, TGFB1, TGFB2
30
Show member pathways
7.5CAPN5, FGF2, SPARC, TGFB1, TGFB2, TIMP1
31
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
32
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
33
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
34
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
35
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
36
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
37
Show member pathways
6.9CTGF, FGF1, FGF2, HGF, MET, TGFB1
38
Show member pathways
6.9CCL2, CTGF, FGF1, FGF2, HGF, MET
39
Show member pathways
6.9CCL2, CTGF, FGF1, FGF2, HGF, MET
40
Show member pathways
6.9CCL2, CTGF, FGF1, FGF2, HGF, MET
41
Show member pathways
6.9CCL2, CTGF, FGF1, FGF2, HGF, MET
42
Show member pathways
6.9CCL2, CTGF, FGF1, FGF2, HGF, MET
43
Show member pathways
6.3CAPN5, CCL2, CTGF, FGF1, FGF2, GFAP

GO Terms for genes affiliated with Vitreoretinopathy, Neovascular Inflammatory

About this section

Cellular components related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrixGO:00310129.7TGFB1, TGFB2, TIMP1, VTN
2basement membraneGO:00056049.4SPARC, TIMP1, VTN
3platelet alpha granule lumenGO:00310938.7HGF, SPARC, TGFB1, TGFB2, TIMP1
4proteinaceous extracellular matrixGO:00055787.5CTGF, FGF1, SPARC, TGFB1, TIMP1, VTN
5extracellular spaceGO:00056156.4ADM, CCL2, CTGF, FGF1, FGF2, HGF
6extracellular regionGO:00055766.0ADM, CCL2, CTGF, FGF1, FGF2, HGF

Biological processes related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1cartilage condensationGO:000150210.8CTGF, TGFB2
2cell-cell junction organizationGO:004521610.7TGFB1, TGFB2
3negative regulation of immune responseGO:005077710.7TGFB1, TGFB2
4negative regulation of macrophage cytokine productionGO:001093610.7TGFB1, TGFB2
5pathway-restricted SMAD protein phosphorylationGO:006038910.7TGFB1, TGFB2
6positive regulation of protein localization to nucleusGO:190018210.7TGFB1, TGFB2
7hyaluronan catabolic processGO:003021410.6FGF2, TGFB1
8salivary gland morphogenesisGO:000743510.6TGFB1, TGFB2
9negative regulation of blood vessel endothelial cell migrationGO:004353710.6FGF2, TGFB1
10positive regulation of blood vessel endothelial cell migrationGO:004353610.6FGF2, TGFB1
11neuron projection regenerationGO:003110210.6ADM, GFAP
12glial cell migrationGO:000834710.6CCL2, TGFB2
13SMAD protein import into nucleusGO:000718410.5TGFB1, TGFB2
14organ inductionGO:000175910.4FGF1, FGF2
15positive regulation of sprouting angiogenesisGO:190367210.4FGF1, FGF2
16regulation of endothelial cell chemotaxis to fibroblast growth factorGO:200054410.4FGF1, FGF2
17hepatocyte growth factor receptor signaling pathwayGO:004801210.4HGF, MET
18negative regulation of hydrogen peroxide-mediated programmed cell deathGO:190129910.4HGF, MET
19epithelial to mesenchymal transitionGO:000183710.4HGF, TGFB1, TGFB2
20cell activationGO:000177510.3TGFB1, TIMP1
21positive regulation of collagen biosynthetic processGO:003296710.2CCL2, CTGF, TGFB1
22positive regulation of peptidyl-tyrosine phosphorylationGO:005073110.2HGF, TGFB1, VTN
23response to progesteroneGO:003257010.2CCL2, TGFB1, TGFB2
24fibroblast growth factor receptor signaling pathwayGO:000854310.2CTGF, FGF1, FGF2
25activation of MAPK activityGO:000018710.1FGF1, FGF2, HGF
26positive regulation of epithelial cell proliferationGO:005067910.1FGF1, FGF2, TGFB1
27positive regulation of gene expressionGO:001062810.1CTGF, FGF2, TGFB1, TGFB2
28positive regulation of MAP kinase activityGO:004340610.1FGF1, FGF2, TGFB1
29positive chemotaxisGO:005091810.1FGF2, HGF, MET
30negative regulation of cell proliferationGO:000828510.0ADM, FGF2, TGFB1, TGFB2
31transforming growth factor beta receptor signaling pathwayGO:000717910.0CCL2, TGFB1, TGFB2
32response to organic substanceGO:00100339.9ADM, TGFB1, TIMP1
33positive regulation of cell divisionGO:00517819.9FGF1, FGF2, TGFB1, TGFB2
34positive regulation of protein phosphorylationGO:00019349.8CTGF, FGF1, FGF2, TGFB1
35response to hypoxiaGO:00016669.8ADM, CCL2, TGFB1, TGFB2
36animal organ regenerationGO:00311009.7ADM, CCL2, HGF, TGFB1
37positive regulation of ERK1 and ERK2 cascadeGO:00703749.7CCL2, CTGF, FGF1, FGF2
38positive regulation of angiogenesisGO:00457669.7ADM, FGF1, FGF2, HGF
39MAPK cascadeGO:00001659.7CCL2, FGF1, FGF2, TGFB1
40positive regulation of endothelial cell migrationGO:00105959.6FGF1, FGF2, SPARC
41response to glucocorticoidGO:00513849.5ADM, CCL2, SPARC
42response to peptide hormoneGO:00434349.5CTGF, SPARC, TIMP1
43angiogenesisGO:00015259.5CCL2, CTGF, FGF1, FGF2, TGFB2
44lung developmentGO:00303249.4CTGF, FGF1, FGF2, SPARC
45cell proliferationGO:00082839.3FGF1, HGF, MET, TGFB1, TGFB2
46extracellular matrix organizationGO:00301989.2FGF2, GFAP, SPARC, TGFB2, VTN
47response to woundingGO:00096119.2ADM, CCL2, CTGF, GFAP, TGFB1, TGFB2
48agingGO:00075688.9ADM, CCL2, CTGF, FGF2, TGFB1, TIMP1
49platelet degranulationGO:00025768.9HGF, SPARC, TGFB1, TGFB2, TIMP1
50positive regulation of cell proliferationGO:00082848.2ADM, CTGF, FGF1, FGF2, HGF, TGFB1

Molecular functions related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1chemoattractant activityGO:004205610.7FGF2, HGF
2fibroblast growth factor receptor bindingGO:000510410.5FGF1, FGF2
3extracellular matrix bindingGO:005084010.1SPARC, VTN
4type II transforming growth factor beta receptor bindingGO:00051149.9TGFB1, TGFB2
5type III transforming growth factor beta receptor bindingGO:00347149.9TGFB1, TGFB2
6integrin bindingGO:00051789.8CTGF, FGF1, GFAP, VTN
7heparin bindingGO:00082019.4CCL2, CTGF, FGF1, FGF2, VTN
8protein tyrosine kinase activityGO:00047139.4FGF1, FGF2, MET
9cytokine activityGO:00051259.3CCL2, FGF2, TGFB1, TGFB2, TIMP1
10growth factor activityGO:00080838.7CTGF, FGF1, FGF2, HGF, TGFB1, TGFB2
11protein bindingGO:00055155.5ADM, CCL2, CTGF, FGF1, FGF2, GFAP

Sources for Vitreoretinopathy, Neovascular Inflammatory

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet