MCID: VTR013
MIFTS: 48

Vitreoretinopathy, Neovascular Inflammatory malady

Categories: Genetic diseases, Eye diseases, Rare diseases

Aliases & Classifications for Vitreoretinopathy, Neovascular Inflammatory

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Aliases & Descriptions for Vitreoretinopathy, Neovascular Inflammatory:

Name: Vitreoretinopathy, Neovascular Inflammatory 49 11 22 67 24
Proliferative Vitreoretinopathy 10 22 12 67 65
Adniv 51 67
Vrni 22 67
Pvr 22 67
Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy 51
 
Neovascular Inflammatory Vitreoretinopathy Autosomal Dominant 67
Vitreoretinopathy, Proliferative 36
Proliferative Vitreo-Retinopathy 65
Vitreoretinopathy Proliferative 47
Retinitis Proliferans 10

Characteristics:

Orphanet epidemiological data:

51
adniv:
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: All ages

HPO:

61
vitreoretinopathy, neovascular inflammatory:
Inheritance: autosomal dominant inheritance


Classifications:

Orphanet: 51 
Rare eye diseases


External Ids:

OMIM49 193235
Disease Ontology10 DOID:9719
MeSH36 D018630
Orphanet51 329211
MedGen34 C1860404
UMLS65 C0242852, C2880931

Summaries for Vitreoretinopathy, Neovascular Inflammatory

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UniProtKB/Swiss-Prot:67 Vitreoretinopathy, neovascular inflammatory: An autoimmune condition of the eye that sequentially mimics uveitis, retinitis pigmentosa, and proliferative diabetic retinopathy as it progresses to complete blindness. Patients present during the second or third decade of life with posterior uveitis and reduction of the electroretinogram b-wave. They become more symptomatic when cataracts, cystoid macular edema, and disk edema diminish visual acuity during the second stage. Severe vision loss begins during the third stage when proliferative retinal neovascularization and epiretinal membranes appear. There is an ongoing pigmentary retinal degeneration and peripheral visual field loss during all stages. In the fourth stage, proliferative vitreoretinopathy causes tractional retinal detachments at the macula and vitreous base. The fifth or end-stage disease is marked by phthisis.

MalaCards based summary: Vitreoretinopathy, Neovascular Inflammatory, also known as proliferative vitreoretinopathy, is related to oral candidiasis and myocardial infarction, and has symptoms including vitreous hemorrhage, posterior retinal neovascularization and large hyperpigmented retinal spots. An important gene associated with Vitreoretinopathy, Neovascular Inflammatory is CAPN5 (Calpain 5), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and IL-4 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. Affiliated tissues include eye and retina, and related mouse phenotypes are respiratory system and muscle.

OMIM:49 Autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV) is a blinding disorder that shares some clinical... (193235) more...

Related Diseases for Vitreoretinopathy, Neovascular Inflammatory

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Diseases related to Vitreoretinopathy, Neovascular Inflammatory via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 406)
idRelated DiseaseScoreTop Affiliating Genes
1oral candidiasis30.2CCL2, CTGF, FN1, TGFB1
2myocardial infarction29.3CTGF, FGF2, FN1, HGF, THBS1, TIMP1
3colorectal cancer27.7FN1, FOS, HGF, MET, TGFB1, TGFB2
4poliomyelitis11.5
5paralytic poliomyelitis11.4
6total anomalous pulmonary venous return11.3
7female stress incontinence11.3
8pericardium disease11.3
9heart conduction disease11.3
10hemopericardium11.3
11cardiac tamponade11.3
12pericardial effusion11.3
13enterocele11.3
14prolapse of female genital organ11.3
15urethral intrinsic sphincter deficiency11.3
16basilar artery insufficiency11.3
17akinetic mutism11.3
18ovarian cystic teratoma11.3
19mature teratoma of the ovary11.3
20urethral diverticulum11.3
21leukemia10.5
22breast cancer10.5
23lymphoma10.5
24endotheliitis10.5
25hepatitis10.4
26cerebritis10.4
27thyroiditis10.4
28chronic myeloproliferative disease10.4FN1, TGFB1
29episodic ataxia10.4CTGF, FN1, TGFB1
30inherited metabolic disorder10.3FGF2, FN1, GFAP
31obesity10.3
32sarcoma10.3
33esophagitis10.3
34lateral ventricle meningioma10.3FN1, GFAP
35amyotrophic lateral sclerosis 1210.3CTGF, FN1, TGFB2
36follicular lymphoma10.3
37coronary artery disease10.3
38artery disease10.3
39lung cancer10.3
40prostatitis10.3
41cervicitis10.3
42adenocarcinoma10.3
43pancreatitis10.3
44neuronitis10.3
45encephalitis10.3
46muscular dystrophy10.3
47oppositional defiant disorder10.3CTGF, HGF, TGFB1
48patau syndrome10.3CCL2, CTGF, TGFB1
49suppurative uveitis10.2CCL2, CTGF, TGFB1
50cystic echinococcosis10.2CTGF, TGFB1, TIMP1

Graphical network of the top 20 diseases related to Vitreoretinopathy, Neovascular Inflammatory:



Diseases related to vitreoretinopathy, neovascular inflammatory

Symptoms for Vitreoretinopathy, Neovascular Inflammatory

About this section

Symptoms by clinical synopsis from OMIM:

193235

Clinical features from OMIM:

193235

HPO human phenotypes related to Vitreoretinopathy, Neovascular Inflammatory:

(show all 7)
id Description Frequency HPO Source Accession
1 vitreous hemorrhage HP:0007902
2 posterior retinal neovascularization HP:0007778
3 large hyperpigmented retinal spots HP:0007658
4 blindness HP:0000618
5 uveitis HP:0000554
6 retinal detachment HP:0000541
7 abnormal electroretinogram HP:0000512

Drugs & Therapeutics for Vitreoretinopathy, Neovascular Inflammatory

About this section

Drugs for Vitreoretinopathy, Neovascular Inflammatory (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Bupivacaineapproved, investigationalPhase 49642180-92-92474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Hydrochloride
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
DepoBupivacaine
 
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
Exparel
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
Racemic bupivacaine
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Vivacaine
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
2
TriamcinoloneapprovedPhase 4, Phase 3448124-94-731307
Synonyms:
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11beta,16alpha,17alpha,21-Tetrahydroxy-9alpha-fluoro-1,4-pregnadiene-3,20-dione
124-94-7
4-08-00-03629 (Beilstein Handbook Reference)
83474-03-7
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy
9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-16alpha-hydroxyprednisolone
9α-fluoro-16α-hydroxyprednisolone
AC-2072
AC1L1LDH
AC1Q5HJC
Adcortyl
Allernaze
Aristocort
Aristocort A
Aristocort Tablets
Aristogel
Aristospan
Azmacort
BPBio1_000154
BRD-K77554836-001-03-3
BRN 2341955
BSPBio_000140
Bio-0662
C21H27FO6
CHEMBL1451
CID31307
CL 19823
Celeste
Cinolone
Cinolone-T
D00385
D014221
DB00620
Delphicort
EINECS 204-718-7
EU-0101179
Fluoxiprednisolone
Fluoxyprednisolone
Flutex
Fougera
HMS1568G22
HMS2090D12
HSDB 3194
Kenacort
Kenacort (TN)
Kenacort-A
Kenacort-AG
Kenacort-Ag
Kenalog
Kenalog in Orabase
Kenalog-10
Kenalog-40
Kenalog-H
LS-698
Ledercort
Lopac0_001179
MLS000028542
MLS001066543
 
MLS002695935
MolPort-002-528-981
Mycolog
NCGC00021580-03
NCGC00021580-04
NCGC00021580-05
NCGC00021580-06
NCGC00021580-07
NCI60_000750
NSC 13397
NSC13397
Nasacort
Nasacort Aq
Nasacort Hfa
Omcilon
Omicilon
Oracort
Oralone
Orion
Polcortolon
Pregna-1,4-diene-3,20-dio
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI)
Prestwick0_000120
Prestwick1_000120
Prestwick2_000120
Prestwick3_000120
Prestwick_438
Rodinolone
S1933_Selleck
SK-Triamcinolone
SMP1_000300
SMR000058333
SPBio_002079
Sk-Triamcinolone
T6376_SIGMA
TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7))
Tiamcinolonum
Tiamcinolonum [INN-Latin]
Tri-Nasal
Triacet
Triacort
Triam-Tablinen
Triamcet
Triamcinalone
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolona [INN-Spanish]
Triamcinolone (JP15/USP/INN)
Triamcinolone Acetonide
Triamcinolone [USAN:INN:BAN:JAN]
Triamcinolone acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Triamcinolonum
Triamcinolonum [INN]
Trianex
Triatex
Tricortale
Triderm
Triesence
Trilone
Tristoject
Trymex
UNII-1ZK20VI6TY
Vetalog
Volon
Volon A
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ
ZINC03882036
droxypregna-1,4-diene-3,20-dione
ione
nchembio.2007.53-comp7
triamcinolone
3
IsotretinoinapprovedPhase 41154759-48-25538, 5282379
Synonyms:
(13-cis)-Retinoate
(13-cis)-Retinoic acid
(13cis)-retinoic acid
(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
(2Z,4E6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
(7E,9E,11E,13Z)-retinoic acid
(7e,9e,11e,13Z)-Retinoic acid
13 Cis-Retinoic Acid
13 cis retinoic acid
13-RA
13-cis RA
13-cis retinoic acid
13-cis-Retinoate
13-cis-Retinoic acid
13-cis-Vitamin A acid
13-cis-Vitamin a acid
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-trans-6-trans-8-trans-nonatetraenoic acid
4-09-00-02388 (Beilstein Handbook Reference)
4759-48-2
97950-17-9
AC-15388
AC1NQZZ4
Absorica
Accutane
Accutane (TN)
Ambap302-79-4
Amnesteem
BML2-E07
BPBio1_000080
BRD-K76723084-001-05-9
BRN 1885770
BSPBio_000072
BSPBio_001331
BSPBio_003345
CCRIS 4286
CHEBI:6067
CHEMBL547
CID5282379
CIP-Isotretinoin
CPD000471891
Claravis
Clarus
D00348
D015474
EINECS 225-296-0
EU-0101081
Epuris
HMS1361C13
HMS1568D14
HMS1791C13
HMS1921D08
HMS1989C13
HMS2092N07
HSDB 3929
IDI1_033801
Isotane
Isotretinoin
Isotretinoin (USP)
 
Isotretinoin Retinoic acid
Isotretinoin Zinc Salt, 13 cis Isomer
Isotretinoin Zinc Salt, 13-cis-Isomer
Isotretinoin [USAN:BAN:INN]
Isotretinoin [USAN:INN:BAN]
Isotretinoina
Isotretinoine
Isotretinoine [INN-French]
Isotretinoino
Isotretinoino [INN-Spanish]
Isotretinoinum
Isotretinoinum [INN-Latin]
Isotrex
LMPR01090021
LS-143465
Lopac0_001081
MLS001074662
MolPort-003-666-394
Myorisan
NCGC00094358-01
NCGC00094358-02
NCGC00094358-03
NCGC00094358-04
NCGC00094358-05
NCGC00094358-06
NCGC00094358-07
NCGC00094358-08
NCGC00094358-09
NCGC00094358-13
Neovitamin A acid
Neovitamin a acid
Prestwick2_000256
Prestwick3_000256
Prestwick_642
R 3255
R3255_SIGMA
Retinoate
Retinoic acid
Ro 4 3780
Ro 4-3780
Ro 43780
Ro-4-3780
Ro-43780
Roaccutan
Roaccutane
Roacutan
SAM002548955
SMR000471891
SPECTRUM1502013
Sotret
Sotret (TN)
Spectrum5_001795
Spectrum5_001937
Teriosal
UNII-EH28UP18IF
Zenatane
cis-RA
cis-Retinoate
cis-Retinoic acid
isotretinoino
4Peripheral Nervous System AgentsPhase 4, Phase 318510
5Immunosuppressive AgentsPhase 4, Phase 310422
6Triamcinolone hexacetonidePhase 4, Phase 3448
7AnestheticsPhase 47385
8Immunologic FactorsPhase 4, Phase 318483
9triamcinolone acetonidePhase 4, Phase 3448
10Triamcinolone diacetatePhase 4, Phase 3448
11Central Nervous System DepressantsPhase 410016
12Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 39988
13Anesthetics, LocalPhase 42347
14glucocorticoidsPhase 4, Phase 33896
15HormonesPhase 4, Phase 311748
16Hormone AntagonistsPhase 4, Phase 310002
17Anti-Inflammatory AgentsPhase 4, Phase 38478
18Dermatologic AgentsPhase 44555
19
ColchicineapprovedPhase 310464-86-86167, 2833
Synonyms:
(S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
30512-31-3
5843-86-7
64-86-8
7-alpha-H-Colchicine
7.alpha.H-Colchicine
7alphaH-Colchicine
AC1L1LXO
ACon1_000353
AI3-31149
AKOS001582887
BB_NC-0737
BPBio1_000535
BRD-K00259736-001-06-5
BSPBio_000485
BSPBio_002083
Benzo(a)heptalen-9(5H)-one
C 9754
C07592
C22H25NO6
C3915_SIGMA
C9754_SIGMA
CCRIS 691
CHEBI:27882
CHEMBL107
CID6167
CPD-9785
Colchicin
Colchicin [German]
Colchicina
Colchicina [Italian]
Colchicine
Colchicine (JP15/USP)
Colchicine (TN)
Colchicine [JAN]
Colchicine, (+-)-Isomer
Colchicine, (R)-Isomer
Colchicine, Colchicum autumnale
Colchicinum
Colchineos
Colchisol
Colchysat
Colcin
Colcrys
Colsaloid
Colstat
Condylon
D003078
D00570
DB01394
DB08117
DivK1c_000753
EINECS 200-598-5
EU-0100310
Goutnil
HMS1569I07
HMS1920A08
HMS2091G16
HMS502F15
HSDB 3044
IDI1_000753
KBio1_000753
KBio2_001322
KBio2_003890
KBio2_006458
 
KBio3_001303
KBioGR_000856
KBioSS_001322
Kolkicin
LOC
LS-279
Lopac0_000310
MEGxp0_001879
MLS001055448
MLS001055448-02
MLS001304089
MLS002153786
MPC-004
Mitigare
MolPort-001-742-594
N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)- acetamide
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[.alpha.]heptalen-7-yl)-acetamide
N-Acetyl trimethylcolchicinic acid methylether
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide
NCGC00025125-01
NCGC00025125-02
NCGC00025125-03
NCGC00025125-04
NCGC00025125-05
NCGC00025125-06
NCGC00025125-07
NCGC00025125-11
NCGC00169157-01
NCGC00169157-02
NCGC00169157-03
NCI60_041659
NChemBio.2007.10-comp20
NINDS_000753
NSC 757
NSC757
Prestwick0_000363
Prestwick1_000363
Prestwick2_000363
Prestwick3_000363
Prestwick_695
S2284_Selleck
SDCCGMLS-0066633.P001
SID26747941
SID49671357
SMR000058323
SPBio_000289
SPBio_002406
SPECTRUM1500205
Spectrum2_000075
Spectrum3_000362
Spectrum4_000298
Spectrum5_000787
Spectrum_000842
Tocris-1364
UNII-SML2Y3J35T
UPCMLD-DP065
UPCMLD-DP065:001
WLN: L B677 MV&T&J CO1 DO1 EO1 JMV1 NO1
ZINC00621853
binds to tubulin
colchicine
inhibits microtubular assembly
nchembio853-comp2
spindle poison
20
Heparinapproved, investigationalPhase 37199005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
21
DalteparinapprovedPhase 32819041-08-1
Synonyms:
Daltepariininatrium
Dalteparin Sodyum
Dalteparin sodium
Dalteparin sodná sůl
Dalteparin-nátrium
Dalteparina sódica
 
Dalteparinnatrium
Dalteparino natrio druska
Dalteparinum Natricum
Dalteparyna sodowa
Daltéparine sodique
Fragmin
Heparin Fragment KABI 2165
Tedelparin
22
FluorouracilapprovedPhase 3168451-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen
23
Dexamethasoneapproved, investigationalPhase 3190950-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Baycadron
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
Dexameth
Dexamethansone
 
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone acetate
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone sodium phosphate
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamethsone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
Ozurdex
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
24Gastrointestinal AgentsPhase 36401
25Protease InhibitorsPhase 34558
26Fibrinolytic AgentsPhase 31567
27Tubulin ModulatorsPhase 34279
28HIV Protease InhibitorsPhase 34558
29Heparin, Low-Molecular-WeightPhase 3286
30Antimitotic AgentsPhase 34296
31Dexamethasone acetatePhase 319091177-87-3
32AntiemeticsPhase 33213
33AnticoagulantsPhase 31760
34Antirheumatic AgentsPhase 38496
35Antineoplastic Agents, HormonalPhase 34256
36BB 1101Phase 31909
37Dexamethasone 21-phosphatePhase 31909
38calcium heparinPhase 3719
39
Bevacizumabapproved, investigationalPhase 21875216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
40Angiogenesis InhibitorsPhase 23688
41Angiogenesis Modulating AgentsPhase 23611

Interventional clinical trials:

(show all 15)
idNameStatusNCT IDPhase
1Postoperative Pain Control Following Vitreoretinal SurgeryCompletedNCT01995045Phase 4
2Isotretinoin for Proliferative VitreoretinopathyActive, not recruitingNCT01445028Phase 4
3Triamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative VitreoretinopathyCompletedNCT00373282Phase 3
4The Silicone StudyCompletedNCT00000140Phase 3
5Oral Colchicine Combined With Intravitreal Infusion of Dexamethasone, LMW Heparin and 5-FU for Management of Proliferative Vitreoretinopathy (PVR)RecruitingNCT00370760Phase 3
6Surgical Management of Pseudophakic and Aphakic Retinal Detachment; a Randomized Clinical TrialRecruitingNCT00370279Phase 3
7Comparison High-Density Silicone Oils in Retinal DetachmentRecruitingNCT00403702Phase 2, Phase 3
8Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal DetachmentActive, not recruitingNCT00370201Phase 3
9The Effect of 5-FU and LMW Heparin on the Rate of Retinal Redetachment After Silicone Oil Removal in Cases of PVRActive, not recruitingNCT00371020Phase 3
10Bevacizumab Against Recurrent Retinal DetachmentNot yet recruitingNCT02192970Phase 2
11Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal DetachmentsCompletedNCT01255293
12Comparison of Two Techniques for Epiretinal or Internal Limiting Membrane PeelRecruitingNCT00892619
13Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery.RecruitingNCT01959568
14Eye Injections of Bevacizumab to See if Medication Helps to Lower Risk of Scar Tissue Development in the Retina and Repeated Retinal Detachment.Active, not recruitingNCT01860586
15Optical Coherence Tomography - Rescan During Dissection of Macular MembranesNot yet recruitingNCT02748421

Search NIH Clinical Center for Vitreoretinopathy, Neovascular Inflammatory


Cochrane evidence based reviews: vitreoretinopathy, proliferative

Genetic Tests for Vitreoretinopathy, Neovascular Inflammatory

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Genetic tests related to Vitreoretinopathy, Neovascular Inflammatory:

id Genetic test Affiliating Genes
1 Vitreoretinopathy, Neovascular Inflammatory22 CAPN5

Anatomical Context for Vitreoretinopathy, Neovascular Inflammatory

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MalaCards organs/tissues related to Vitreoretinopathy, Neovascular Inflammatory:

33
Eye, Retina

Animal Models for Vitreoretinopathy, Neovascular Inflammatory or affiliated genes

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MGI Mouse Phenotypes related to Vitreoretinopathy, Neovascular Inflammatory:

38 (show all 17)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.4ADM, CTGF, MET, TGFB1, TGFB2, THBS1
2MP:00053698.1ADM, FGF2, FN1, GFAP, MET, TGFB1
3MP:00053808.1ADM, CTGF, FN1, FOS, HGF, MET
4MP:00053827.9CTGF, FN1, FOS, MET, SPARC, TGFB1
5MP:00053717.9CTGF, FN1, FOS, MET, TGFB2, THBS1
6MP:00053897.8ADM, FGF2, FN1, FOS, TGFB1, TGFB2
7MP:00028737.6CTGF, FGF1, FN1, FOS, GFAP, MET
8MP:00020067.4FGF2, FN1, FOS, MET, SPARC, TGFB1
9MP:00053917.3CTGF, FGF2, FOS, GFAP, MET, SPARC
10MP:00053907.1CTGF, FGF2, FN1, FOS, SPARC, TGFB1
11MP:00053846.9ADM, CTGF, FGF2, FN1, FOS, GFAP
12MP:00053856.4ADM, CTGF, FGF2, FN1, GFAP, HGF
13MP:00053786.2CAPN5, CTGF, FN1, FOS, GFAP, HGF
14MP:00107686.1ADM, CAPN5, CTGF, FGF2, FN1, FOS
15MP:00053875.2ADM, CAPN5, CCL2, FN1, FOS, GFAP
16MP:00053765.0ADM, CTGF, FGF1, FGF2, FN1, FOS
17MP:00053974.9ADM, CAPN5, FGF1, FGF2, FN1, FOS

Publications for Vitreoretinopathy, Neovascular Inflammatory

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Variations for Vitreoretinopathy, Neovascular Inflammatory

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UniProtKB/Swiss-Prot genetic disease variations for Vitreoretinopathy, Neovascular Inflammatory:

67
id Symbol AA change Variation ID SNP ID
1CAPN5p.Arg243LeuVAR_069277
2CAPN5p.Leu244ProVAR_069278

Clinvar genetic disease variations for Vitreoretinopathy, Neovascular Inflammatory:

5
id Gene Variation Type Significance SNP ID Assembly Location
1CAPN5NM_004055.4(CAPN5): c.728G> T (p.Arg243Leu)single nucleotide variantPathogenicrs397514601GRCh37Chr 11, 76826469: 76826469
2CAPN5NM_004055.4(CAPN5): c.731T> C (p.Leu244Pro)single nucleotide variantPathogenicrs397514602GRCh37Chr 11, 76826472: 76826472

Expression for genes affiliated with Vitreoretinopathy, Neovascular Inflammatory

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Search GEO for disease gene expression data for Vitreoretinopathy, Neovascular Inflammatory.

Pathways for genes affiliated with Vitreoretinopathy, Neovascular Inflammatory

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Pathways related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idSuper pathwaysScoreTop Affiliating Genes
110.0TGFB1, TGFB2
210.0TGFB1, TGFB2
39.8FN1, TGFB1, TGFB2
49.7FGF2, TGFB1, TGFB2
59.7CTGF, FN1, VTN
6
Show member pathways
9.7TGFB1, TGFB2, VTN
79.7FGF2, FN1, VTN
89.5FGF2, FN1, TGFB1, TGFB2
9
Show member pathways
9.5FGF2, FN1, TGFB1, TGFB2
109.5FGF2, FN1, THBS1
119.4CTGF, FGF1, TGFB1, TGFB2
129.4FN1, THBS1, VTN
139.4HGF, MET, TGFB1
149.4CCL2, FN1, TGFB1, TGFB2
159.3SPARC, TGFB1, TGFB2, VTN
169.2FGF2, HGF, MET, TGFB1
17
Show member pathways
9.1FGF2, TGFB1, THBS1, VTN
189.1FGF1, FGF2, TGFB1, THBS1
199.1FGF2, FN1, SPARC, TGFB1, TGFB2
208.9ADM, FOS, TIMP1
218.9FOS, TGFB1, THBS1
228.8CCL2, FOS, TGFB1, TGFB2
238.8CCL2, FOS, GFAP, TGFB1
248.7FOS, SPARC, TGFB1, TGFB2
258.7FN1, SPARC, TGFB1, THBS1, VTN
268.6FGF1, FGF2, FOS, TGFB1, TGFB2
27
Show member pathways
8.5FGF1, FGF2, HGF, MET, THBS1
288.5FGF1, FOS, HGF, MET
298.5FN1, SPARC, TIMP1, TIMP2, VTN
30
Show member pathways
8.4FOS, HGF, MET, TGFB1, TGFB2
31
Show member pathways
8.4CCL2, FGF2, FN1, FOS, TIMP1
328.3CCL2, HGF, MET, TGFB1, TGFB2, THBS1
337.9FGF2, FN1, HGF, MET, TGFB1, TGFB2
34
Show member pathways
7.6CAPN5, FN1, FOS, HGF, MET, THBS1
357.6FGF1, FGF2, FN1, HGF, MET, THBS1
36
Show member pathways
7.6CAPN5, CCL2, FN1, FOS, TGFB1, TGFB2
377.5FGF1, FGF2, FN1, FOS, HGF, MET
38
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
39
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
40
Show member pathways
7.3CTGF, FGF1, FGF2, HGF, MET, TGFB1
41
Show member pathways
7.1CTGF, FGF1, FGF2, FN1, HGF, MET
42
Show member pathways
7.0CAPN5, FGF2, FN1, SPARC, TGFB1, TGFB2
43
Show member pathways
6.5CTGF, FGF1, FGF2, FOS, HGF, MET
44
Show member pathways
6.5CTGF, FGF1, FGF2, FOS, HGF, MET
45
Show member pathways
6.2CTGF, FGF1, FGF2, FOS, HGF, MET
46
Show member pathways
6.1CCL2, CTGF, FGF1, FGF2, FOS, HGF
47
Show member pathways
6.1CCL2, CTGF, FGF1, FGF2, FOS, HGF
48
Show member pathways
6.1CCL2, CTGF, FGF1, FGF2, FOS, HGF
49
Show member pathways
6.1CCL2, CTGF, FGF1, FGF2, FOS, HGF
50
Show member pathways
5.5CAPN5, CCL2, CTGF, FGF1, FGF2, FN1

GO Terms for genes affiliated with Vitreoretinopathy, Neovascular Inflammatory

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Cellular components related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.5SPARC, THBS1

Biological processes related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

(show top 50)    (show all 57)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of macrophage cytokine productionGO:001093610.7TGFB1, TGFB2
2SMAD protein import into nucleusGO:000718410.7TGFB1, TGFB2
3negative regulation of immune responseGO:005077710.7TGFB1, TGFB2
4pathway-restricted SMAD protein phosphorylationGO:006038910.7TGFB1, TGFB2
5organ inductionGO:000175910.6FGF1, FGF2
6positive regulation of collagen biosynthetic processGO:003296710.5CCL2, TGFB1
7hyaluronan catabolic processGO:003021410.5FGF2, TGFB1
8salivary gland morphogenesisGO:000743510.5TGFB1, TGFB2
9glial cell migrationGO:000834710.4CCL2, TGFB2
10cell-matrix adhesionGO:000716010.3CTGF, FN1, VTN
11positive regulation of macrophage chemotaxisGO:001075910.2CCL2, THBS1
12epithelial to mesenchymal transitionGO:000183710.2HGF, TGFB1, TGFB2
13positive regulation of cell divisionGO:005178110.2FGF1, FGF2, TGFB2
14positive regulation of fibroblast migrationGO:001076310.2TGFB1, THBS1
15positive regulation of MAP kinase activityGO:004340610.2FGF1, FGF2, TGFB1
16positive regulation of chemotaxisGO:005092110.2TGFB1, THBS1
17cell activationGO:000177510.2FN1, TGFB1, TIMP1
18positive regulation of peptidyl-tyrosine phosphorylationGO:005073110.1HGF, TGFB1, VTN
19organ regenerationGO:003110010.1ADM, CCL2, TGFB1
20negative regulation of blood vessel endothelial cell migrationGO:004353710.1FGF2, TGFB1, THBS1
21cell cycle arrestGO:000705010.1TGFB1, TGFB2, THBS1
22positive regulation of blood vessel endothelial cell migrationGO:004353610.0FGF2, TGFB1, THBS1
23negative regulation of membrane protein ectodomain proteolysisGO:005104510.0TIMP1, TIMP2
24positive regulation of ERK1 and ERK2 cascadeGO:00703749.9CCL2, FGF1, FGF2
25positive regulation of endothelial cell migrationGO:00105959.9FGF2, SPARC, THBS1
26activation of MAPK activityGO:00001879.9FGF2, HGF, THBS1
27positive regulation of protein kinase B signalingGO:00518979.9FGF2, TGFB1, THBS1
28response to gravityGO:00096299.9FOS, SPARC
29peptidyl-tyrosine phosphorylationGO:00181089.9FGF1, FGF2, MET
30positive chemotaxisGO:00509189.8FGF2, HGF, MET
31response to progesteroneGO:00325709.8CCL2, TGFB1, THBS1
32negative regulation of cell proliferationGO:00082859.7ADM, FGF2, TGFB1, TGFB2
33platelet activationGO:00301689.7FN1, SPARC, TGFB1, TGFB2
34negative regulation of angiogenesisGO:00165259.7CCL2, SPARC, THBS1
35response to glucocorticoidGO:00513849.6ADM, CCL2, FN1, SPARC
36positive regulation of angiogenesisGO:00457669.6ADM, FGF1, FGF2, HGF
37response to woundingGO:00096119.6ADM, CCL2, CTGF, FN1, TGFB1
38blood coagulationGO:00075969.6HGF, TGFB1, TGFB2, THBS1
39platelet degranulationGO:00025769.5FN1, HGF, TGFB1, TGFB2, TIMP1
40response to peptide hormoneGO:00434349.5CTGF, SPARC, TIMP1
41transforming growth factor beta receptor signaling pathwayGO:00071799.5CCL2, TGFB1, TGFB2
42female pregnancyGO:00075659.4ADM, FOS, TGFB1
43agingGO:00075689.1ADM, CCL2, FOS, TGFB1
44cell adhesionGO:00071559.1CCL2, CTGF, FN1, THBS1, VTN
45response to hypoxiaGO:00016669.0ADM, CCL2, TGFB2, THBS1
46angiogenesisGO:00015258.8CCL2, CTGF, FGF1, FGF2, FN1, TGFB2
47positive regulation of cell proliferationGO:00082848.3CTGF, FGF1, FGF2, FN1, HGF, TGFB1
48response to drugGO:00424937.8CCL2, FOS, TGFB1, TGFB2, THBS1, TIMP2
49extracellular matrix organizationGO:00301987.8FGF2, FN1, GFAP, TGFB1, TGFB2, THBS1
50signal transductionGO:00071657.7ADM, CCL2, CTGF, FGF1, FGF2, MET

Molecular functions related to Vitreoretinopathy, Neovascular Inflammatory according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1integrin bindingGO:00051789.2CTGF, FN1, THBS1, VTN

Sources for Vitreoretinopathy, Neovascular Inflammatory

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet