MCID: VLV031
MIFTS: 25

Vulva Adenocarcinoma malady

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Vulva Adenocarcinoma

Aliases & Descriptions for Vulva Adenocarcinoma:

Name: Vulva Adenocarcinoma 12 14
Adenocarcinoma of the Vulva 12
Adenocarcinoma of Vulva 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2098
NCIt 47 C6380
UMLS 69 C1336975

Summaries for Vulva Adenocarcinoma

Disease Ontology : 12 A vulva carcinoma that derives from epithelial cells of glandular origin.

MalaCards based summary : Vulva Adenocarcinoma, also known as adenocarcinoma of the vulva, is related to apocrine adenocarcinoma and skeletal tuberculosis. An important gene associated with Vulva Adenocarcinoma is UPK3A (Uroplakin 3A), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Bladder cancer. The drugs Acetaminophen and Imiquimod have been mentioned in the context of this disorder. Related phenotypes are cellular and endocrine/exocrine gland

Related Diseases for Vulva Adenocarcinoma

Diseases related to Vulva Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 139)
id Related Disease Score Top Affiliating Genes
1 apocrine adenocarcinoma 29.5 CDX2 CEACAM5 KRT20 KRT7
2 skeletal tuberculosis 10.3 CDKN2A ERBB2
3 perivascular epithelioid cell tumor 10.3 KRT20 UPK3A
4 split-hand with obstructive uropathy, spina bifida, and diaphragmatic defects 10.3 KRT20 PIP
5 posterior myocardial infarction 10.3 CDKN2A ERBB2
6 microglandular adenosis 10.3 KRT7 UPK3A
7 breast sarcoma 10.3 ERBB2 PIP
8 radiculopathy 10.3 KRT20 KRT7
9 adult myxoid chondrosarcoma 10.3 KRT20 KRT7
10 steroid-induced glaucoma - borderline 10.3 KRT20 KRT7
11 non specific chronic endometritis 10.3 KRT20 KRT7
12 suppurative lymphadenitis 10.3 CDKN2A KRT7
13 nonossifying fibromyxoid tumor 10.3 KRT20 KRT7
14 spasmodic dysphonia 10.2 KRT20 KRT7
15 agenesis and aplasia of uterine body 10.2 KRT20 KRT7
16 pleuropneumonia 10.2 CDKN2A LINC01191
17 decubitus ulcer 10.2 CD86 CDKN2A
18 poliomyelitis 10.2 ERBB2 PIP
19 skin sarcoma 10.2 CEACAM5 ERBB2
20 yaws 10.2 CD86 CEACAM5
21 suppression amblyopia 10.2 CD86 CEACAM5
22 degenerative myopia 10.2 KRT20 KRT7
23 klatskin's tumor 10.2 KRT20 KRT7 UPK3A
24 oro-mandibular-limb hypogenesis syndrome 10.2 CDKN2A ERBB2
25 hypodermyiasis 10.2 CEACAM5 ITGA2
26 central nervous system mature teratoma 10.2 ERBB2 PIP
27 paraphimosis 10.2 CDKN2A KRT20 KRT7
28 hypoglossal nerve disease 10.2 CEACAM5 PIP
29 estrogen-receptor positive breast cancer 10.2 CDKN2A ERBB2 PIP
30 deep angioma 10.2 CEACAM5 KRT7
31 ovarian endometrioid cystadenofibroma 10.2 CD86 CEACAM5
32 osteosarcoma arising in bone paget's disease 10.2 CEACAM5 KRT7
33 progesterone-receptor positive breast cancer 10.2 CDKN2A ERBB2 PIP
34 breast adenocarcinoma 10.2 CEACAM5 KRT7
35 bronchus mucoepidermoid carcinoma 10.2 KRT20 KRT7 PIP
36 adenocarcinoma 10.2
37 anal carcinoma in situ 10.2 CDKN2A KRT7
38 nervous system hibernoma 10.1 ERBB2 KRT7 PIP
39 laryngeal mucoepidermoid carcinoma 10.1 CEACAM5 KRT7
40 infiltrating angiolipoma 10.1 CEACAM5 ERBB2
41 prostate lymphoma 10.1 CEACAM5 KRT7
42 sclerosing breast papilloma 10.1 CEACAM5 KRT7
43 parietal lobe neoplasm 10.1 CEACAM5 PIP
44 pulmonary artery choriocarcinoma 10.1 CD86 CEACAM5 ERBB2
45 ladd syndrome 10.1 CDKN2A ERBB2 KRT20 UPK3A
46 cd40 ligand deficiency 10.1 CDKN2A PTCRA
47 autonomic nervous system neoplasm 10.1 CDKN2A KRT20 KRT7
48 basaloid squamous cell carcinoma 10.1 CD86 CEACAM5 ERBB2
49 trachea squamous cell carcinoma 10.1 CDKN2A CEACAM5 ERBB2
50 female breast axillary tail cancer 10.1 CEACAM5 KRT7

Graphical network of the top 20 diseases related to Vulva Adenocarcinoma:



Diseases related to Vulva Adenocarcinoma

Symptoms & Phenotypes for Vulva Adenocarcinoma

MGI Mouse Phenotypes related to Vulva Adenocarcinoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.56 CD86 CDKN2A CDX2 ERBB2 INPP4B ITGA2
2 endocrine/exocrine gland MP:0005379 9.17 PIP PTCRA CD86 CDKN2A CDX2 ERBB2

Drugs & Therapeutics for Vulva Adenocarcinoma

Drugs for Vulva Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetaminophen Approved Phase 3 103-90-2 1983
2
Imiquimod Approved, Investigational Phase 3 99011-02-6 57469
3
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
4
Petrolatum Approved Phase 3 8009-03-8
5 Adjuvants, Immunologic Phase 3
6 Analgesics Phase 3
7 Analgesics, Non-Narcotic Phase 3
8 Anesthetics Phase 3
9 Anesthetics, Local Phase 3
10 Anti-Arrhythmia Agents Phase 3
11 Antipyretics Phase 3
12 Central Nervous System Depressants Phase 3
13 Dermatologic Agents Phase 3
14 Diuretics, Potassium Sparing Phase 3
15 Emollients Phase 3
16 Interferon Inducers Phase 3
17 interferons Phase 3
18 Peripheral Nervous System Agents Phase 3
19 Sodium Channel Blockers Phase 3
20
Formaldehyde Approved, Vet_approved 50-00-0 712

Interventional clinical trials:


id Name Status NCT ID Phase
1 Topical 5% Imiquimod Cream for Vulvar Paget's Disease Enrolling by invitation NCT02385188 Phase 3
2 Collecting Tumor Samples From Patients With Gynecological Tumors Completed NCT00897442
3 Prevalence of Anal Dysplasia and Anal Cancer in Women With Cervical, Vaginal and Vulvar Dysplasia and Cancer Recruiting NCT02140021
4 A Study of ChemoFx® Chemoresponse Assay in Solid Tumors - ChemoFx® Registry Study Terminated NCT01271959

Search NIH Clinical Center for Vulva Adenocarcinoma

Genetic Tests for Vulva Adenocarcinoma

Anatomical Context for Vulva Adenocarcinoma

Publications for Vulva Adenocarcinoma

Variations for Vulva Adenocarcinoma

Expression for Vulva Adenocarcinoma

Search GEO for disease gene expression data for Vulva Adenocarcinoma.

Pathways for Vulva Adenocarcinoma

Pathways related to Vulva Adenocarcinoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.2 CD86 CEACAM5 ITGA2
2 10.66 CDKN2A ERBB2 UPK3A

GO Terms for Vulva Adenocarcinoma

Biological processes related to Vulva Adenocarcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of immature T cell proliferation in thymus GO:0033088 8.62 CDKN2A ERBB2

Sources for Vulva Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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