MCID: VLV044
MIFTS: 44

Vulvar Intraepithelial Neoplasia malady

Categories: Reproductive diseases, Rare diseases

Aliases & Classifications for Vulvar Intraepithelial Neoplasia

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Sources:
52Orphanet, 66UMLS, 67UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Vulvar Intraepithelial Neoplasia:

Name: Vulvar Intraepithelial Neoplasia 52
Vulval Intraepithelial Neoplasia 66
 
Vulvar Intraepithelial Tumor 52

Classifications:



External Ids:

Orphanet52 ORPHA137583
UMLS via Orphanet67 C0346210

Summaries for Vulvar Intraepithelial Neoplasia

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Wikipedia:69 The term Vulvar intraepithelial neoplasia (VIN) refers to particular changes that can occur in the skin... more...

MalaCards based summary: Vulvar Intraepithelial Neoplasia, also known as vulval intraepithelial neoplasia, is related to cervicitis and oral tuberculosis, and has symptoms including pruritus and macule. An important gene associated with Vulvar Intraepithelial Neoplasia is TP53 (Tumor Protein P53), and among its related pathways are RHO GTPases activate IQGAPs and EGFR Signaling Pathway. Affiliated tissues include skin, t cells and testes, and related mouse phenotypes are respiratory system and digestive/alimentary.

Related Diseases for Vulvar Intraepithelial Neoplasia

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Diseases related to Vulvar Intraepithelial Neoplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 187)
idRelated DiseaseScoreTop Affiliating Genes
1cervicitis30.2MMP2, MMP9, TIMP1, TIMP2
2oral tuberculosis10.8CDH1, TP53
3salivary gland adenoid cystic carcinoma10.7CDKN2A, TP53
4pregnancy adenoma10.7CDH1, KRT5
5biliary papillomatosis10.7CDKN2A, TP53
6renal pelvis inverted papilloma10.7CDH1, TP53
7extrahepatic bile duct adenocarcinoma10.6CDH1, CTNNB1, TP53
8periapical granuloma10.6CDH1, CTNNB1, TP53
9epidural spinal canal angiolipoma10.6CDKN2A, VWF
10split hand split foot malformation autosomal recessive10.6CDKN2A, TP53
11jumping frenchmen of maine10.6TERT, TP53, VWF
12hypoglossal nerve neoplasm10.6CDKN2A, SOX2, TP53
13adenofibroma10.6CDKN2A, TP53, VWF
14oligodendroglioma10.6CDKN2A, KRT5, TP53
15x-linked congenital generalized hypertrichosis10.6CDKN2A, TERT, TP53
1612p12.1 microdeletion syndrome10.6CDH1, CDKN2A, CTNNB1
17fallopian tube carcinoma10.5CDH1, CDKN2A, TP53
18ascending colon cancer10.5CDKN2A, SOX2, TP53
19plasma protein metabolism disease10.5CDH1, CTNNB1, TP53
20pasli disease10.5MMP9, TP53
21duodenal somatostatinoma10.5BIRC5, CDKN2A, TP53
22vulva cancer10.5
23desmoplastic infantile astrocytoma10.5BIRC5, CDKN2A, CTNNB1
24richter's syndrome10.5CDH1, CDKN2A, TP53
25antidepressant or antipsychotic toxicity or dose selection10.5BIRC5, MMP9, TP53
26mediastinal melanocytic neurilemmoma10.5CTNNB1, KRT7
27trochlear nerve neoplasm10.5CDKN2A, H2AFX, KRT5
28cervix endometrial stromal tumor10.5CDKN2A, CTNNB1, TP53
29adenoid squamous cell carcinoma10.5CDKN2A, TP53
30tamoxifen-related endometrial lesion10.5KRT5, KRT7, TP53
31active cochleovestibular meniere's disease10.4CDKN2A, H2AFX
32tumor predisposition syndrome10.4CDH1, CDKN2A, TP53
33nodular degeneration of cornea10.4CDKN2A, CTNNB1, TP53
34dubin-johnson syndrome10.4CDKN2A, TERT, TP53
35oral lichen planus10.4CDH1, MMP9, TP53
36ductal carcinoma in situ10.4CDH1, CDKN2A, KRT5, TP53
37milker's nodule10.4CDH1, CDKN2A, KRT5, TP53
38novak syndrome10.4KRT5, KRT7, TP53
39vulva basal cell carcinoma10.4CDH1, KRT7, TP53
40estrogen-receptor negative breast cancer10.4CDH1, CDKN2A, KRT5, TP53
41nerve fibre bundle defect10.4KRT5, KRT7, TP53
42small cell sarcoma10.4KRT7, SOX2, TP53
43papillary carcinoma10.4BIRC5, KRT7, TP53
44pyoderma10.4KRT7, TERT, TP53
45lichen sclerosus10.4
46hemangioma of lung10.4CDH1, KRT7, TP53
47actinic keratosis10.4CDKN2A, TIMP2, TP53
48persian gulf syndrome10.4CDH1, KRT5, KRT7
49pancreatic somatostatinoma10.3CDH1, CDKN2A, CTNNB1, TP53
50adrenal cortical carcinoma10.3CDH1, CDKN2A, TP53

Graphical network of the top 20 diseases related to Vulvar Intraepithelial Neoplasia:



Diseases related to vulvar intraepithelial neoplasia

Symptoms for Vulvar Intraepithelial Neoplasia

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UMLS symptoms related to Vulvar Intraepithelial Neoplasia:


pruritus, macule

Drugs & Therapeutics for Vulvar Intraepithelial Neoplasia

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Drugs for Vulvar Intraepithelial Neoplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
ImiquimodPhase 2, Phase 313599011-02-657469
Synonyms:
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
1-isobutyl-1H-imidazo(4,5-c)quinolin-4-amine
1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
3M Brand of Imiquimod
4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline
4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
99011-02-6
AC-529
AC1L1N2I
AC1Q4YO9
Aldara
Aldara (TN)
Aldara, Imiquimod
BB_SC-2107
BIDD:GT0859
Beselna
C056493
CHEBI:36704
CHEMBL1282
CID57469
D02500
DB00724
DZ-2636
FT-0080222
HMS2090M14
 
I06-0624
I06-2289
I0747
I5159_SIGMA
IMIQUIMOD
Imiquimod
Imiquimod (JAN/USAN/INN)
Imiquimod [USAN:INN]
Imiquimod acetate
Imiquimodum
LS-178395
MLS000083577
MTD-39
MolPort-002-507-845
NCGC00070736-02
NSC369100
R 837
R-837
S 26308
S-26308
S1211_Selleck
SMR000048307
STK583860
TL8006059
TMX-101
UNII-P1QW714R7M
ZINC19632912
Zartra
Zyclara
imiquimod
2interferonsPhase 2, Phase 32112
3
Aluminum hydroxidePhase 319421645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
4
MentholPhase 321842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol

Interventional clinical trials:

(show all 24)
idNameStatusNCT IDPhase
1A Randomized Trial of Surgical Treatments for Vulvar and Vaginal DysplasiaCompletedNCT00394758Phase 3
2Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED)CompletedNCT00092521Phase 3
3A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501) in Women (V501-019)CompletedNCT00090220Phase 3
4ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-TrialCompletedNCT00941252Phase 2, Phase 3
5Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial NeoplasiaRecruitingNCT01861535Phase 3
6Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )VaccineActive, not recruitingNCT01735006Phase 3
7A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent GirlsActive, not recruitingNCT02562508Phase 3
8Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial NeoplasiaNot yet recruitingNCT02875561Phase 3
9Imiquimod Treatment of CIN LesionsTerminatedNCT02329171Phase 3
10Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cancer, or Endometrial CancerTerminatedNCT00577317Phase 3
11Immunevasion of Human Papillomavirus (HPV) in Vulvar Intraepithelial Neoplasia 2/3 and Anogenital Warts and Efficiency and Mechanisms of Imiquimod TreatmentCompletedNCT00941811Phase 2
12The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom PrevalenceCompletedNCT01986725Phase 2
13Dose-Ranging Study of Quadrivalent Human Papillomavirus (HPV) (Types 6,11,16,18) L1 Virus-Like Particle (VLP) Vaccine (V501-007)(COMPLETED)CompletedNCT00365716Phase 2
14Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVINActive, not recruitingNCT02596074Phase 2
15SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous CondylomaCompletedNCT01676792Phase 0
16GARDASIL™ Vaccine Impact in Population Study (V501-033)CompletedNCT01077856
17Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive TherapyCompletedNCT00727636
18Prevalence of Anal Dysplasia and Anal Cancer in Women With Cervical, Vaginal and Vulvar Dysplasia and CancerRecruitingNCT02140021
19Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their PrecursorsRecruitingNCT02735109
20A New Patient Reported Outcome Instrument to Assess Symptom Experience in Women With Vulvar Neoplasms (WOMAN-PRO)RecruitingNCT01300663
21Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval DiseaseRecruitingNCT02223975
22Long-term Follow-up of Broad Spectrum Human Papillomavirus (HPV) Vaccine Study in Women (V503-021)Active, not recruitingNCT02653118
23Evaluation of Long-term HPV Vaccine EfficacyEnrolling by invitationNCT01393470
24Colposcopy and High Resolution Anoscopy in Screening For Anal Dysplasia in Patients With Cervical, Vaginal, or Vulvar Dysplasia or CancerWithdrawnNCT01313104

Search NIH Clinical Center for Vulvar Intraepithelial Neoplasia

Genetic Tests for Vulvar Intraepithelial Neoplasia

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Anatomical Context for Vulvar Intraepithelial Neoplasia

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MalaCards organs/tissues related to Vulvar Intraepithelial Neoplasia:

34
Skin, T cells, Testes, Endothelial, Lung

Animal Models for Vulvar Intraepithelial Neoplasia or affiliated genes

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MGI Mouse Phenotypes related to Vulvar Intraepithelial Neoplasia:

39 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.4CDKN2A, CTNNB1, KLRC1, MMP2, MMP9, SOX2
2MP:00053818.4CDH1, CDKN2A, CTNNB1, KRT5, MMP9, SOX2
3MP:00053898.1CDH1, CDKN2A, CTNNB1, H2AFX, MMP9, SOX2
4MP:00053857.2CDH1, CDKN2A, CTNNB1, H2AFX, MMP2, MMP9
5MP:00020067.1CDH1, CDKN2A, CTNNB1, H2AFX, MMP1, MMP2
6MP:00053797.0BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, RPS6
7MP:00053976.7BIRC5, CDKN2A, CTNNB1, H2AFX, HAVCR2, KLRC1
8MP:00053786.6CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2, KRT5
9MP:00107686.5BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
10MP:00053846.4BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
11MP:00053876.0BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
12MP:00053764.5BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, KLRC1

Publications for Vulvar Intraepithelial Neoplasia

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Articles related to Vulvar Intraepithelial Neoplasia:

(show top 50)    (show all 226)
idTitleAuthorsYear
1
Vulvar and Vaginal Cancer, Vulvar Intraepithelial Neoplasia 3 and Vaginal Intraepithelial Neoplasia 3: Experience of a Referral Institute. (27430086)
2016
2
Usual-type vulvar intraepithelial neoplasia: report of a case and its dermoscopic features. (27419656)
2016
3
Localized amyloidosis of the vulva with and without vulvar intraepithelial neoplasia: report of a series. (25149547)
2014
4
Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival. (25220367)
2014
5
Pathways of vulvar intraepithelial neoplasia and squamous cell carcinoma. (23190170)
2013
6
Focused ultrasound therapy for vulvar intraepithelial neoplasia in a mice model. (23187305)
2013
7
Treatment of vulvar intraepithelial neoplasia with topical 5% imiquimod cream. (23219095)
2013
8
Rapid spontaneous regression of acute-onset vulvar intraepithelial neoplasia 3 in young women: a case series. (22207153)
2012
9
Optical coherence tomography in vulvar intraepithelial neoplasia. (23214182)
2012
10
Vulvar intraepithelial neoplasia (VIN 2/3): comparing clinical outcomes and evaluating risk factors for recurrence. (22867736)
2012
11
Expression pattern of class I histone deacetylases in vulvar intraepithelial neoplasia and vulvar cancer: a tissue microarray study. (22029821)
2011
12
Differentiated vulvar intraepithelial neoplasia is often found in lesions, previously diagnosed as lichen sclerosus, which have progressed to vulvar squamous cell carcinoma. (21057461)
2011
13
HPV-negative vulvar intraepithelial neoplasia (VIN) with basaloid histologic pattern: an unrecognized variant of simplex (differentiated) VIN. (19730361)
2009
14
Women's perception of the outcome of the surgical management of vulvar intraepithelial neoplasia. (19160655)
2008
15
Women's experiences with vulvar intraepithelial neoplasia. (19012714)
2008
16
A nonsurgical treatment for vulvar intraepithelial neoplasia. (18769666)
2008
17
Imiquimod 5% cream reduced lesion size in vulvar intraepithelial neoplasia. (18836111)
2008
18
Vulvar intraepithelial neoplasia (erythroplasia of Queyrat). (18786281)
2008
19
Langerhans cell density and high-grade vulvar intraepithelial neoplasia in women with human immunodeficiency virus infection. (17576336)
2007
20
Concordance of gross surgical and final fixed margins in vulvar intraepithelial neoplasia 3 and vulvar cancer. (16967630)
2006
21
Synchronous vulvar intraepithelial neoplasia (VIN) of warty type and cervical intraepithelial neoplasia (CIN): case report. (17183865)
2006
22
Use of the female sexual function index in women with vulvar intraepithelial neoplasia. (16809252)
2006
23
p53 immunostaining in lichen sclerosus is related to ischaemic stress and is not a marker of differentiated vulvar intraepithelial neoplasia (d-VIN). (16430473)
2006
24
Vulvar intraepithelial neoplasia: varied signs, varied symptoms: what you need to know. (15777042)
2005
25
Vulvar intraepithelial neoplasia (VIN)--diagnostic and therapeutic challenges. (12807248)
2003
26
Loop electrosurgical excision procedure in vulvar intraepithelial neoplasia treatment. (17051029)
2002
27
Vulvar intraepithelial neoplasia treated with cavitational ultrasonic surgical aspiration. (11925129)
2002
28
Epidemiology, diagnosis and treatment of vulvar intraepithelial neoplasia. (11801875)
2002
29
Photodynamic therapy of vulvar intraepithelial neoplasia III using topically applied 5-aminolevulinic acid. (11136571)
2001
30
Trends in vulvar neoplasia. Increasing incidence of vulvar intraepithelial neoplasia and squamous cell carcinoma of the vulva in young women. (10986677)
2000
31
A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive. (10999722)
2000
32
Immunohistochemical localization of telomerase hTERT protein and analysis of clonality in multifocal vulvar intraepithelial neoplasia. (10989637)
2000
33
The contribution of MIB 1 in the accurate grading of vulvar intraepithelial neoplasia. (10690171)
1999
34
Human papillomavirus DNA in multicentric vulvar intraepithelial neoplasia. (9475186)
1998
35
Differentiating vulvar intraepithelial neoplasia from nonneoplastic epithelial disorders. The toluidine blue test. (9749417)
1998
36
Vulvar intraepithelial neoplasia in women with HIV. (11361951)
1998
37
Pattern of various cytokeratins of normal vulva, vulvar intraepithelial neoplasia (VIN) and vulvar carcinoma]. (9746912)
1998
38
Angiogenesis in vulvar intraepithelial neoplasia. (9062159)
1997
39
Clinicopathologic analysis of 370 cases of vulvar intraepithelial neoplasia. Italian Study Group on Vulvar Disease. (8887191)
1996
40
Vulvar intraepithelial neoplasia and vulvar cancer. (8784883)
1996
41
The natural history of vulvar intraepithelial neoplasia. (7547730)
1995
42
Biologic behavior of vulvar intraepithelial neoplasia. Histologic and clinical parameters. (8383203)
1993
43
Keratin expression in normal vulva, non-neoplastic epithelial disorders, vulvar intraepithelial neoplasia, and invasive squamous cell carcinoma. (1723057)
1991
44
Vulvar intraepithelial neoplasia. A clinicopathologic study of 60 cases. (2177508)
1990
45
Expression of the human papillomavirus type 16 genome in SK-v cells, a line derived from a vulvar intraepithelial neoplasia. (2157796)
1990
46
Combination of surgical excision and carbon dioxide laser vaporization for multifocal vulvar intraepithelial neoplasia. (3348303)
1988
47
Association of human papillomavirus infection and vulvar intraepithelial neoplasia: a morphological and immunohistochemical study of 30 cases. (3030906)
1987
48
Human fibroblast interferon in cervical and vulvar intraepithelial neoplasia associated with papilloma virus infection. (6099344)
1984
49
Management of vulvar intraepithelial neoplasia by carbon dioxide laser. (6806733)
1982
50
Vulvar intraepithelial neoplasia: correlation of nuclear DNA content and the presence of a human papilloma virus (HPV) structural antigen. (6277449)
1982

Variations for Vulvar Intraepithelial Neoplasia

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Expression for genes affiliated with Vulvar Intraepithelial Neoplasia

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Search GEO for disease gene expression data for Vulvar Intraepithelial Neoplasia.

Pathways for genes affiliated with Vulvar Intraepithelial Neoplasia

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Pathways related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

(show all 25)
idSuper pathwaysScoreTop Affiliating Genes
110.0CDH1, CTNNB1
29.8CDH1, CTNNB1, TP53
39.8CDH1, CTNNB1, TP53
49.6KRT5, MMP1, TP53
5
Show member pathways
9.6BIRC5, CDH1, CTNNB1, TP53
69.6BIRC5, CDH1, CTNNB1, SOX2
7
Show member pathways
9.5CDKN2A, CTNNB1, SOX2, TP53
89.5BIRC5, MMP9, TERT, TP53
99.5CDKN2A, CTNNB1, TERT, TP53
109.3CDH1, CTNNB1, MMP1, TP53
119.3CDKN2A, CTNNB1, MMP2, TP53
129.3MMP1, MMP9, TIMP2
139.2MMP1, MMP2, MMP9
14
Show member pathways
9.2CDH1, CTNNB1, MMP2, MMP9
159.2CDH1, CTNNB1, MMP2, MMP9
169.0CDH1, CTNNB1, MMP2, MMP9, TERT
17
Show member pathways
8.8MMP2, MMP9, TIMP1, TIMP2, VWF
18
Show member pathways
8.7MMP1, RPS6, TIMP1, TP53
198.6MMP1, MMP2, MMP9, TIMP1, TIMP2
20
Show member pathways
8.6MMP1, MMP2, MMP9, TIMP1, TIMP2
218.5CDH1, CDKN2A, MMP1, MMP2, MMP9, TP53
228.4CTNNB1, MMP2, MMP9, RPS6, TP53
238.4BIRC5, CDH1, CTNNB1, MMP1, MMP2, MMP9
24
Show member pathways
8.3CDH1, MMP1, MMP2, MMP9, TIMP1, TIMP2
258.1BIRC5, CDH1, CDKN2A, CTNNB1, MMP1, MMP2

GO Terms for genes affiliated with Vulvar Intraepithelial Neoplasia

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Cellular components related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1flotillin complexGO:001660010.5CDH1, CTNNB1
2catenin complexGO:001634210.5CDH1, CTNNB1
3apical junction complexGO:004329610.5CDH1, CTNNB1
4proteinaceous extracellular matrixGO:00055788.7MMP1, MMP2, MMP9, TIMP1, TIMP2, VWF
5extracellular exosomeGO:00700626.6CDH1, CTNNB1, H2AFX, HAVCR2, KRT10, KRT5

Biological processes related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of membrane protein ectodomain proteolysisGO:005104510.4TIMP1, TIMP2
2cellular response to indole-3-methanolGO:007168110.3CDH1, CTNNB1
3replicative senescenceGO:009039910.2CDKN2A, TERT, TP53
4response to cytokineGO:00340979.7CTNNB1, TIMP1, TIMP2
5collagen catabolic processGO:00305749.6MMP1, MMP2, MMP9
6positive regulation of vascular smooth muscle cell proliferationGO:19047079.4MMP2, MMP9, TERT
7extracellular matrix disassemblyGO:00226178.4CDH1, MMP1, MMP2, MMP9, TIMP1, TIMP2
8negative regulation of apoptotic processGO:00430668.3BIRC5, MMP9, RPS6, TERT, TIMP1, TP53

Molecular functions related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chaperone bindingGO:005108710.3BIRC5, TP53, VWF
2protease bindingGO:00020209.8TIMP1, TIMP2, TP53, VWF
3protein bindingGO:00055154.5BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2

Sources for Vulvar Intraepithelial Neoplasia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet