MCID: VLV044
MIFTS: 47

Vulvar Intraepithelial Neoplasia malady

Categories: Reproductive diseases, Cancer diseases, Rare diseases

Aliases & Classifications for Vulvar Intraepithelial Neoplasia

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Sources:
51Orphanet, 65UMLS, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Vulvar Intraepithelial Neoplasia:

Name: Vulvar Intraepithelial Neoplasia 51
Vulval Intraepithelial Neoplasia 65
 
Vulvar Intraepithelial Tumor 51

Classifications:



External Ids:

Orphanet51 137583
UMLS via Orphanet66 C0346210
UMLS65 C0346210

Summaries for Vulvar Intraepithelial Neoplasia

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Wikipedia:68 The term Vulvar intraepithelial neoplasia (VIN) refers to particular changes that can occur in the skin... more...

MalaCards based summary: Vulvar Intraepithelial Neoplasia, also known as vulval intraepithelial neoplasia, is related to urethra inverted papilloma and signet ring basal cell carcinoma, and has symptoms including maculeand pruritus. An important gene associated with Vulvar Intraepithelial Neoplasia is BIRC5 (Baculoviral IAP Repeat Containing 5), and among its related pathways are Validated targets of C-MYC transcriptional activation and RHO GTPases activate IQGAPs. Affiliated tissues include skin, breast and lung, and related mouse phenotypes are taste/olfaction and no phenotypic analysis.

Related Diseases for Vulvar Intraepithelial Neoplasia

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Diseases related to Vulvar Intraepithelial Neoplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 100)
idRelated DiseaseScoreTop Affiliating Genes
1urethra inverted papilloma10.7BIRC5, TP53
2signet ring basal cell carcinoma10.7KRT5, TP53
3uterine corpus adenosarcoma10.7BIRC5, TP53
4histoplasmosis10.7KRT5, TP53
5external ear squamous cell carcinoma10.7KRT5, TP53
6cervical non-keratinizing squamous cell carcinoma10.6KRT5, TP53
7high molecular weight kininogen deficiency10.6KRT5, TP53
8vulvar clear cell hidradenocarcinoma10.6KRT5, TP53
9cystadenoma10.6KRT5, TP53
10secretory meningioma10.6BIRC5, TERT
11intracystic papillary adenoma10.6TP53, VWF
12mucocele of salivary gland10.6KRT5, TP53
13aortic aneurysm10.6KRT5, TP53
14autosomal dominant complex spastic paraplegia type 9a10.5BIRC5, TP53
15spindle cell carcinoma10.5CDH1, TP53
16common bile duct disease10.5TP53, VWF
17vulva cancer10.5
18cervicitis10.5
19lateral ventricle meningioma10.5CDH1, TP53
20familial congenital fourth cranial nerve palsy10.5CDH1, TP53
21breast ductal adenoma10.4CDH1, KRT5
22corneal neovascularization10.4CDH1, TP53
23pyelonephritis10.4CDH1, TP53
24nasal cavity squamous cell carcinoma10.4CDH1, KRT5
25ovary neuroendocrine neoplasm10.4CTNNB1, TP53
26superficial basal cell carcinoma10.4CDH1, TP53
27lichen sclerosus10.4
28ladd syndrome10.4BIRC5, TERT, TP53
29schwannoma of twelfth cranial nerve10.4SOX2, TP53
30intracranial sinus thrombosis10.4CDH1, TP53
31skin pilomatrix carcinoma10.3CTNNB1, KRT5
32cardiovascular organ benign neoplasm10.3CTNNB1, TP53
33multiple skull base meningioma10.3CTNNB1, TP53
34anus basaloid carcinoma10.2KRT5, SOX2
35mediastinal neurilemmoma10.2CTNNB1, TP53
36clove syndrome, somatic10.2KRT5, TP53
37adjustment disorder10.2KRT5, TP53
38pleomorphic carcinoma10.2CDH1, KRT5, TP53
39lipomatosis10.2BIRC5, TP53
40lymphatic system cancer10.2CDH1, KRT5, TP53
41eye carcinoma in situ10.2CDH1, KRT5, TP53
42vascular dementia10.2CDH1, KRT5, TP53
43estrogen-receptor positive breast cancer10.2CDH1, KRT5, TP53
44hallermann-streiff syndrome10.2CDH1, KRT5, TP53
45integumentary system cancer10.2CTNNB1, KRT5
46goldmann-favre syndrome10.2CDH1, CTNNB1
47pasteurellosis10.2CDH1, TERT, TP53
48bone ameloblastoma10.1CTNNB1, TERT, TP53
49malignant peritoneal solitary fibrous tumor10.1CDH1, KRT5
50vaginitis10.1

Graphical network of the top 20 diseases related to Vulvar Intraepithelial Neoplasia:



Diseases related to vulvar intraepithelial neoplasia

Symptoms for Vulvar Intraepithelial Neoplasia

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UMLS symptoms related to Vulvar Intraepithelial Neoplasia:


macule, pruritus

Drugs & Therapeutics for Vulvar Intraepithelial Neoplasia

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FDA approved drugs:

id Drug Name Active Ingredient(s)15 Company Approval Date
1
Gardasil15 41 quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine Merck June 2006
FDA Label: Gardasil
Disease/s that Drug Treats:Cervical Cancer Caused by Human Papillomavirus
Indications and Usage:15 GARDASIL is a vaccine indicated in girls and women 9 through 26years of age for the prevention of the following diseases caused byHuman Papillomavirus (HPV) types included in the vaccine: Cervical, vulvar, vaginal, and anal cancer caused by HPV types 16and 18 (1.1) Genital warts (condyloma acuminata) caused by HPV types 6 and11 (1.1)And the following precancerous or dysplastic lesions caused by HPVtypes 6, 11, 16, and 18: Cervical intraepithelial neoplasia (CIN) grade 2/3 and Cervicaladenocarcinoma in situ (AIS) (1.1) Cervical intraepithelial neoplasia (CIN) grade 1 (1.1) Vulvar intraepithelial neoplasia (VIN) grade 2 and grade 3 (1.1) Vaginal intraepithelial neoplasia (VaIN) grade 2 and grade 3 (1.1) Anal intraepithelial neoplasia (AIN) grades 1, 2, and 3 (1.1)GARDASIL is indicated in boys and men 9 through 26 years of age forthe prevention of the following diseases caused by HPV types includedin the vaccine: Anal cancer caused by HPV types 16 and 18 (1.2) Genital warts (condyloma acuminata) caused by HPV types 6 and11 (1.2)And the following precancerous or dysplastic lesions caused by HPVtypes 6, 11, 16, and 18: Anal intraepithelial neoplasia (AIN) grades 1, 2, and 3. (1.2)Limitations of GARDASIL Use and Effectiveness: GARDASIL does not eliminate the necessity for women tocontinue to undergo recommended cervical cancer screening.(1.3, 17) Recipients of GARDASIL should not discontinue anal cancerscreening if it has been recommended by a health care provider.(1.3, 17) GARDASIL has not been demonstrated to provide protectionagainst disease from vaccine and non-vaccine HPV types to whicha person has previously been exposed through sexual activity.(1.3, 14.4, 14.5) GARDASIL is not intended to be used for treatment of activeexternal genital lesions; cervical, vulvar, vaginal, and analcancers; CIN; VIN; VaIN, or AIN. (1.3) GARDASIL has not been demonstrated to protect againstdiseases due to HPV types not contained in the vaccine. (1.3,14.4, 14.5) Not all vulvar, vaginal, and anal cancers are caused by HPV, andGARDASIL protects only against those vulvar, vaginal, and analcancers caused by HPV 16 and 18. (1.3) GARDASIL does not protect against genital diseases not causedby HPV. (1.3) Vaccination with GARDASIL may not result in protection in allvaccine recipients. (1.3) GARDASIL has not been demonstrated to prevent HPV-relatedCIN 2/3 or worse in women older than 26 years of age. (14.7)
DrugBank Targets: -
Mechanism of Action:15 
Target: humoral immune response
Action: inducer
FDA: HPV only infects human beings. Animal studies with analogous animal papillomaviruses suggest thatthe efficacy of L1 VLP vaccines may involve the development of humoral immune responses. Humanbeings develop a humoral immune response to the vaccine, although the exact mechanism of protectionis unknown.

Drugs for Vulvar Intraepithelial Neoplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Imiquimodapproved, investigationalPhase 2, Phase 313199011-02-657469
Synonyms:
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
1-isobutyl-1H-imidazo(4,5-c)quinolin-4-amine
1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
3M Brand of Imiquimod
4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline
4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
99011-02-6
AC-529
AC1L1N2I
AC1Q4YO9
Aldara
Aldara (TN)
Aldara, Imiquimod
BB_SC-2107
BIDD:GT0859
Beselna
C056493
CHEBI:36704
CHEMBL1282
CID57469
D02500
DB00724
DZ-2636
FT-0080222
HMS2090M14
I06-0624
 
I06-2289
I0747
I5159_SIGMA
IMIQUIMOD
Imiquimod
Imiquimod (JAN/USAN/INN)
Imiquimod [USAN:INN]
Imiquimod acetate
Imiquimodum
LS-178395
MLS000083577
MTD-39
MolPort-002-507-845
NCGC00070736-02
NSC369100
R 837
R-837
S 26308
S-26308
S1211_Selleck
SMR000048307
STK583860
TL8006059
TMX-101
UNII-P1QW714R7M
Vyloma
ZINC19632912
Zartra
Zyclara
imiquimod
2
Aluminum hydroxideapprovedPhase 3178
Synonyms:
Al(OH)3
Aluminiumhydroxid
 
Aluminum Hydroxide
Aluminum hydroxide
Dermadrox
3
MentholapprovedPhase 319992216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
999 Itch Relief
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
Absorbine Back Therapeutic Pain Relief
Absorbine Jr
Absorbine Jr Ultra Strength Pain Relieving
Absorbine Jr.
Absorbine Jr. Back
Algomend Pain Relief
Alhua Huogan Pain Relieving Patch
Aloemint Skin Aid
Amar Ice
Analgesic
Anc Neverpain External Analgesic
Anti Itch
Army Health Pain Reliever
Arthri-support
Arthri-zen Relief
Arthripain Relief
Arthritis Relief
Aspercreme Heat
Aspercreme Max No Mess Roll On
Assured Cold N Hot Pain Relief Menthol
Assured Extra Strength Cold N Hot
Assured Ice Cold Topical Analgesic
Assured Muscle Rub
Assured Pain Relief Hot Menthol
Atopalm Pain Relieving
Aurorae Healing Pain Relieving Roll-on
Avapta
Avedana Pain Relieving Roll On
Avedana Pain-relieving
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
Babyganics Cold Relief Chest Rub
Barox
Barox BODY CARE MASSAGE
Barox Body Care Massage Relax Refresh Revital
Being Well Extra Strength Menthol Heat
Bengay Ultra Strength Large Size
Bengay Ultra Strength Pain Relieving Large Size
Bengay Ultra Strength Pain Relieving Regular Size
Bengay Ultra Strength Regular Size
Bengay Vanishing Scent
Bengay Zero Degrees Menthol Pain Relieving
Bentasil SUGAR FREE BLACKCURRANT SOFT Texture
Bentasil SUGAR FREE CHERRY SOFT Texture
Bentasil SUGAR FREE HONEY LEMON SOFT Texture
Berri-freez
Besthealth Cherry
Besthealth Cough Suppressant Sugar Free Black Cherry Flavor
Besthealth Cough Suppressant Sugar Free Honey Lemon Flavor
Besthealth Honey Lemon
Besthealth Menthol
Bio 2 Brazilian Heat Brazilian Heat
Bio-scriptives Extreme Pr
Bioblast Pain Relief
Bioflexor
Biofreeze
Biofreeze Colorless
Biofreeze Colorless Roll-on
Biofreeze Roll-on
Biorelief Ice Pain Relieving
Blistex Ivarest Medicated Poison Ivy Cleansing Foam
Blue Gel Pain Relieving
Blue Ice
Blue Ice Analgesic
Blue Ice Analgesic Gel
Blue Ice Pain Relieving
Body
Budpack Muscle Rub
Budpak Muscle Rub
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Canker Complete Canker Sore Relief
Caswell No. 540
Celadrin
Cepacol Sore Throat From Post Nasal Drip
Cepacol Sore Throat Regular Strength
Ching Wan Hung Soothing Herbal Balm
Choice Personal Care Theraputic Blue Ice
Cold Hot Patch
Cold Spot Point Relief
Coldaid
Cool N Heat Patch For Back Extra Strength
Coralite Extra Strength Menthol Pain Relief Sleeve - Knee
Coralite Extra Strength Menthol Pain Relief Sleeve - Wrist
Coralite Pain Relief
Counteract Cough Drops Honey Lemon
Counteract Cough Drops Orchard Cherry
Cryogel Island Rain Natural Pain Relieving Vitaminerals
Cvs Cold Hot Medicated
Cvs Soothing Itch Relief
Cvs Sore Muscle Rub Vanishing Scent
Cvs Therapeutic Menthol Gel
Cvs Therapeutic Menthol Pain Reliever
Cvs Tropical Citrus Cough
Cvs Ultra Strength Pain Relieving
Cvs Vanishing Scent Muscle Rub
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
Dg Health Extra Strength Medicated
Dg Health Pain Relieving
Dg Ice Cold Analgesic
Diapedic Foot Treatment
DivK1c_000820
Dorflex Icy Hot Flexible, Large
Dorflex Icy Hot Flexible, Small
Dorflex Icy Hot Flexible, XL
Dr. Blue
Dt Ice Cold Analgesic
Dual Action Cherry Cough Suppressant Oral Anesthetic
Dynafreeze
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
Easy
Eb301ap Pain Relief
Eb301ct Bruise Pain Relief
Eb302 Arthritis Relief
Ecolyptus Pain Relieving Muscle Rub
Efac Pain Relieving
Elgin Pain Relief
Equaline Blue Ice Pain Relieving
Equate Menthol Extra Strength
Eros Iron Man
Eucalyptamint
Eucerin Calming Itch Relief Treatment
Extra Strength Cold N Hot Pain Relief Medicated
Extra Strength Pain Relief Therapy
Extra Strength Stopain Cold Pain Relieving
Extra Strength Stopain Cold Pain Relieving Roll On
FEMA No. 2665
Family Care Maximum Strength Medicated Anti Itch
Fast Freeze
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
Flexall Pain Relieving
Flexgen
Fluaid
Foot Works Achy Foot Massager Pain Relieving
Gold Bond Foot Extra Strength
Gold Bond Medicated Foot
Gold Bond Pain Relieving Foot
Gold Bond Pain Relieving Foot Roll On
Green Bamboo
Green Guard Cough Drop Relief
HMS1922G13
HMS2092L14
HMS502I22
HSDB 5662
HSDB 593
Halls Apple Cider
Halls Butterscotch
Halls Cherry
Halls Extra Strong Menthol
Halls Honey Lemon
Halls Ice Peppermint
Halls MENTHO-LYPTUS
Halls Melon Splash
Halls Menthol
Halls Mentholyptus
Halls Mocha Mint
Halls Naturals Honey Lemon Chamomile
Halls Plus Cherry
Halls Plus Honey
Halls Plus Strawberry
Halls Spearmint
Halls Strawberry
Halls Sugar Free Black Cherry
Halls Sugar Free Citrus Blend
Halls Sugar Free Extra Strong Menthol
Halls Sugar Free Honey Berry
Halls Sugar Free Honey Lemon
Halls Sugar Free Mountain Menthol
Halls Tropical Fruit
Hallsmelon Splash Melon Splash
Hallssugar Free Extra Sugar Free Extra Strong Menthol
Han Honey Loquat Syrup
Hanbang Cataplasma
Harmon Extra Strength Pain Relieving
Harmon Extra Strength Pain Relieving Roll-on
Headache crystals
Health Smart Medicated Foot
Herbion Naturals Honey Lemon
Herbion Naturals Honey Lemon Cough Drops
Herbion Naturals Honey-Lemon Cough Drops
Herbion Naturals Mint Cough Drops
Herbion Naturals Orange
Herbion Naturals Orange Cough Drops
Hexahydrothymol
Hielo Ardiente
Honibe
 
Hot Ice Soothing Analgesic Gel
Huitomi Slimming Sports
Humphreys Bendito Alcoholado
I06-1216
I14-7371
IDI1_000820
Ice
Ice Cold Analgesic
Ice Cold Topical Analgesic Gel
Ice External Analgesic Leader
Ice Quake
Ice Quake Muscle Rub
Icy Cool Maximum Strength
Icy Hot
Icy Hot Back
Icy Hot Medicated
Icy Hot Medicated No Mess Applicator
Icy Hot Medicated Roll Large
Icy Hot Medicated Roll Medium
Icy Hot Medicated Roll, Large
Icy Hot Medicated Roll, Medium
Icy Hot Medicated, Advanced Relief
Icy Hot Medicated, Back
Icy Hot Medicated, XL
Icy Hot Naturals
Icy Hot Power Gel
Icy Hot Vanishing Scent
Icyhot Medicated
Imada Four Seasons Safe Analgesic Balm
Jakemans Blueberry
Jakemans Cherry
Jakemans Peppermint
K2 Cold Therapy
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
Kay Medic Menthol Pain Relief
Kool Comfort
Kool Comfort Pain Relieving Roll-on
Kpp Triple Action
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
La Jiao Feng Shi Gao
Lander Polar Ice
Leader Cough Drops Cherry Flavor
Leader Cough Drops Honey Lemon
Leader Cough Drops Menthol Flavor
Leader Extra Strength Medicated Pain Relief Patch
Leader Sugar Free Cough Drops Black Cherry
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
Linkus Lozenges Cough Suppressant/Oral Anesthetic
Low Sugar Cherry Flavor Fishermans Friend Menthol Cough Suppressant
Ludens Honey Lemon Throat Drops
Ludens Honey Licorice Throat Drops
Ludens Original Menthol Throat Drops
Lurosil
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Makesense Extra Strength Muscle Rub
Maxfit Freeze Gel
Maybelline New York Baby Lips Dr Rescue Medicated Balm
Medi First Plus Cherry Cough Drops
Medi-first Cherry Cough Drops
Medic Ice
Medicated Body Powder
Medicated Pain Relief
Mediflex
Medique Medikoff Drops
Medique Sugar Free Medikoff Drops
Meditowel PAIN RELIEF
Meijer Cherry Cough Drops
Meijer Honey Lemon Cough Drops
Meijer Menthol Cough Drops
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol Fresh Cough Suppressant
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Mentholatum Pain Relief Extra Strength
Mentholatum Sports Pain Relief Cold
Menthomenthol
Menthyl alcohol
Mineral Ice Pain Relieving
Miracle Foot Repair
Miracle Foot Repair Cream
Miracle Of Aloe Rub Roll On
Miracle Pain Cream
Moisture Therapy Anti-Itch
MolPort-000-849-729
MolPort-001-793-392
Moore Medical Cherry Cough Suppressant/anesthetic Drops
Moore Medical Sugar Free Black Cherry Cough Suppressant/anesthetic Drops
Moore Medical Sugar Free Menthol Cough Suppressant/anesthetic Drops
Mr Dudleys Topical Pain Relief
Muscle
Muscle Rub Ultra Strength Pain Relieving
Myo-breathe
Myorx Low Dose Pain Relieving
Myorx Pain Relieving
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Nan San Easy Flex Pain Relieving
Natural Cherry Honey Herb Throat Drops
Natural Herb cough drop
Natural Honey Herb Cough Suppressant Throat Drops
Natural Lemon Mint Herb Throat Drops
Natural Pain Relieving Lavender Breeze Cryogel
Natures Choice Cool Hot Ice
Natures Sunshine Products Everflex Topical Analgesic Pain Relief
Neoisomenthol
Nice Assorted
Nice Cherry
Nice Citrus
Nice Cool Mint
Nice Honey Lemon
Nice Menthol
No Pain More Gain
North Cough Drop
Numotizine
Olbas Lozenges Maximun Strength
Olbas Pastilles
Original Extra Strong All Natural Fishermans Friend Menthol Cough Suppressant
Ortho-nesic
Osmoflex
Oxyrub Pain Relief
Pain Relief Balmpreferred Plus Ph Preferred Plus Pharmacy
Pain Relief Therapy Patch
Pain Reliever
Pain Relieving
Pain Relieving Analgesic
Pain Relieving Patch
Pain Relieving Patch Ultra Strength
Pain Relieving Patch Ultra Strength ULTRA STRENGTH
Panitrol XR
Paraid Extra Strength Menthol Pain Relief Sleeve Knee Large Ankles Elbows
Patch Scherer Labs
Patch Walgreens
Peppermint camphor
Perfect Purity Hotice
Perfect Purity Medicated Foot Powder
Perform
Personal Care Extra Strength Cold Hot
Personal Care Ice Cold
Plaster MandAHerbalPlaster
Po Sum On Medicated
Polar Frost Cold
Power Relief
Preferred Plus Body Powder
Premier Value Medicated Foot Powder
Q Health Pain Relief Spray
Quickflex
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Raw Heat
Raw Ice
Reactice Reactivating Ice Baume
Red Lion Relief
Relief Pain Relieving Cream
Rexall Vanishing Scent Pain Relieving
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Screamin Menthol Toast
Sella Natural
Skin So Soft Bug Guard Plusitch Relief itch relief
Smith Bros Honey Lemon Cough Drops
Smith Bros Menthol Eucalyptus Cough Drops
Smith Bros Sugar-free Black Cherry Cough Drops
Sof Skin Icy Blue
Sofskin Ice Analgesic
Sombra Cool Therapy
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Stopain Cold Pain Relieving
Stopain Cold Professional Strength Pain Relieving
Stopain Extra Strength Pain Relieving
Sub-zero COOL PAIN RELIEVING
Sugar Free Cherry Fishermans Friend Menthol Cough Suppressant
Sugar Free Cherry Herb Throat Drops
Sugar Free Lemon Mint Herb Throat Drops
Sugar Free Mountain Herb Cough Suppressant Throat Drops
Sugar Free Original Swiss Herb Cough Suppressant Throat Drops
Sugar Free Refreshing Mint Fishermans Friend Menthol Cough Suppressant
Sugar Free Swiss Cherry Herb Throat Drops
The Medicine Shoppe Extra Strength Pain Relieving
The Original Natural Herb Cough Drops
Therafreeze
Theraid
Therapeutic Relief Preferred Plus Pharmacy
Theraplus Plus
Throat Coat
Tianhe Guben Yaoshen Tie Gao
Top Care Medicated
Topcare Medicated
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
Ultra Strength Stopain Pain Relieving
Us Favorite Cold Pain Relieving
Vaporizing Colds Rub
Vicks Vapodrops Cough Relief
Vitaminerals Inc. Cryogel Natural Pain Relieving
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
Walgreens Aloe Vera Cooling
Watermelon Frost Sore Throat
Wellpatch Backache Pain Relief
Xtracare Ice Cold Topical Analgesic Gel
Youngevity Invision CM
Yun Xiang Jing
ZINC01482164
Zhong Hua Jiu Patch
Zims Arnica Max
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
4VaccinesPhase 3, Phase 26085
5interferonsPhase 2, Phase 31930
6Adjuvants, ImmunologicPhase 2, Phase 31783
7Immunologic FactorsPhase 2, Phase 318483
8AnestheticsPhase 37385
9Aluminum sulfatePhase 379
10Immunosuppressive Agents10422

Interventional clinical trials:

(show all 23)
idNameStatusNCT IDPhase
1A Randomized Trial of Surgical Treatments for Vulvar and Vaginal DysplasiaCompletedNCT00394758Phase 3
2Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED)CompletedNCT00092521Phase 3
3A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501) in Women (V501-019)CompletedNCT00090220Phase 3
4ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-TrialCompletedNCT00941252Phase 2, Phase 3
5Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial NeoplasiaRecruitingNCT01861535Phase 3
6Imiquimod Treatment of CIN LesionsRecruitingNCT02329171Phase 3
7Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )VaccineActive, not recruitingNCT01735006Phase 3
8A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent GirlsActive, not recruitingNCT02562508Phase 3
9Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cancer, or Endometrial CancerTerminatedNCT00577317Phase 3
10Immunevasion of Human Papillomavirus (HPV) in Vulvar Intraepithelial Neoplasia 2/3 and Anogenital Warts and Efficiency and Mechanisms of Imiquimod TreatmentCompletedNCT00941811Phase 2
11The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom PrevalenceCompletedNCT01986725Phase 2
12Dose-Ranging Study of Quadrivalent Human Papillomavirus (HPV) (Types 6,11,16,18) L1 Virus-Like Particle (VLP) Vaccine (V501-007)(COMPLETED)CompletedNCT00365716Phase 2
13Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVINRecruitingNCT02596074Phase 2
14SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous CondylomaCompletedNCT01676792Phase 0
15GARDASIL™ Vaccine Impact in Population Study (V501-033)CompletedNCT01077856
16Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive TherapyCompletedNCT00727636
17Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their PrecursorsRecruitingNCT02735109
18Prevalence of Anal Dysplasia and Cancer in WomenRecruitingNCT02140021
19A New Patient Reported Outcome Instrument to Assess Symptom Experience in Women With Vulvar Neoplasms (WOMAN-PRO)RecruitingNCT01300663
20Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval DiseaseRecruitingNCT02223975
21Long-term Follow-up of Broad Spectrum Human Papillomavirus (HPV) Vaccine Study in Women (V503-021)Active, not recruitingNCT02653118
22Evaluation of Long-term HPV Vaccine EfficacyEnrolling by invitationNCT01393470
23Colposcopy and High Resolution Anoscopy in Screening For Anal Dysplasia in Patients With Cervical, Vaginal, or Vulvar Dysplasia or CancerWithdrawnNCT01313104

Search NIH Clinical Center for Vulvar Intraepithelial Neoplasia

Genetic Tests for Vulvar Intraepithelial Neoplasia

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Anatomical Context for Vulvar Intraepithelial Neoplasia

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MalaCards organs/tissues related to Vulvar Intraepithelial Neoplasia:

33
Skin, Breast, Lung, Prostate, Eye, T cells, Liver

Animal Models for Vulvar Intraepithelial Neoplasia or affiliated genes

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MGI Mouse Phenotypes related to Vulvar Intraepithelial Neoplasia:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053949.5CTNNB1, SOX2, TERT
2MP:00030128.2CDH1, CTNNB1, KRT5, SOX2, TP53, VWF
3MP:00020067.9CDH1, CTNNB1, H2AFX, SOX2, TERT, TP53
4MP:00053817.9CDH1, CTNNB1, KRT5, SOX2, TERT, TP53
5MP:00053797.2BIRC5, CDH1, CTNNB1, H2AFX, RPS6, SOX2
6MP:00053977.0BIRC5, CTNNB1, H2AFX, HAVCR2, KLRC1, TERT
7MP:00053786.8CDH1, CTNNB1, H2AFX, HAVCR2, KRT5, SOX2
8MP:00053766.1BIRC5, CDH1, CTNNB1, H2AFX, KLRC1, RPS6
9MP:00107686.1BIRC5, CDH1, CTNNB1, H2AFX, HAVCR2, KRT5
10MP:00053846.1BIRC5, CDH1, CTNNB1, H2AFX, HAVCR2, RPS6
11MP:00053875.8BIRC5, CDH1, CTNNB1, H2AFX, HAVCR2, KLRC1

Publications for Vulvar Intraepithelial Neoplasia

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Articles related to Vulvar Intraepithelial Neoplasia:

(show top 50)    (show all 217)
idTitleAuthorsYear
1
Efficacy of 5% imiquimod cream on vulvar intraepithelial neoplasia in Korea: pilot study. (25673934)
2015
2
An update on vulvar intraepithelial neoplasia: terminology and a practical approach to diagnosis. (24399036)
2014
3
Localized amyloidosis of the vulva with and without vulvar intraepithelial neoplasia: report of a series. (25149547)
2014
4
Immunohistochemical expression of SOX2 in vulvar intraepithelial neoplasia and squamous cell carcinoma. (23518916)
2013
5
Safety and efficacy of topical cidofovir to treat high-grade perianal and vulvar intraepithelial neoplasia in HIV-positive men and women. (23032420)
2013
6
Pathways of vulvar intraepithelial neoplasia and squamous cell carcinoma. (23190170)
2013
7
Focused ultrasound therapy for vulvar intraepithelial neoplasia in a mice model. (23187305)
2013
8
Anti-HPV16 E2 protein T-cell responses and viral control in women with usual vulvar intraepithelial neoplasia and their healthy partners. (22590583)
2012
9
Treatment failure in patients with HPV 16-induced vulvar intraepithelial neoplasia: understanding different clinical responses to immunotherapy. (22913259)
2012
10
Rapid spontaneous regression of acute-onset vulvar intraepithelial neoplasia 3 in young women: a case series. (22207153)
2012
11
Optical coherence tomography in vulvar intraepithelial neoplasia. (23214182)
2012
12
Vulvar intraepithelial neoplasia (VIN 2/3): comparing clinical outcomes and evaluating risk factors for recurrence. (22867736)
2012
13
Expression pattern of class I histone deacetylases in vulvar intraepithelial neoplasia and vulvar cancer: a tissue microarray study. (22029821)
2011
14
The re-infection rate of high-risk HPV and the recurrence rate of vulvar intraepithelial neoplasia (VIN) usual type after surgical treatment. (21873951)
2011
15
Cervical and Vulvar Intraepithelial Neoplasia after Treatment with Oral Isotretinoin for Severe Acne Vulgaris. (20652114)
2009
16
A cluster of vulvar cancer and vulvar intraepithelial neoplasia in young Australian indigenous women. (18766449)
2009
17
Women's perception of the outcome of the surgical management of vulvar intraepithelial neoplasia. (19160655)
2008
18
Women's experiences with vulvar intraepithelial neoplasia. (19012714)
2008
19
A nonsurgical treatment for vulvar intraepithelial neoplasia. (18769666)
2008
20
Imiquimod 5% cream reduced lesion size in vulvar intraepithelial neoplasia. (18836111)
2008
21
Pathologic audit of 164 consecutive cases of vulvar intraepithelial neoplasia. (16633069)
2006
22
Concordance of gross surgical and final fixed margins in vulvar intraepithelial neoplasia 3 and vulvar cancer. (16967630)
2006
23
Immunohistochemical expression of p16 and p53 in vulvar intraepithelial neoplasia and squamous cell carcinoma of the vulva. (16998595)
2006
24
Synchronous vulvar intraepithelial neoplasia (VIN) of warty type and cervical intraepithelial neoplasia (CIN): case report. (17183865)
2006
25
Re: "Is the assumed natural history of vulvar intraepithelial neoplasia III based on enough evidence? A systematic review of 3322 published patients". (16472846)
2006
26
Medical management of vulvar intraepithelial neoplasia. (16205189)
2005
27
Squamous vulvar intraepithelial neoplasia: 2004 modified terminology, ISSVD Vulvar Oncology Subcommittee. (16419625)
2005
28
Treatment of undifferentiated vulvar intraepithelial neoplasia with 5% imiquimod cream: a prospective study of 12 cases. (15492184)
2004
29
The role of angiogenesis in vulvar cancer, vulvar intraepithelial neoplasia, and vulvar lichen sclerosus as determined by microvessel density analysis. (12713988)
2003
30
Misdiagnosis of high-grade vulvar intraepithelial neoplasia (VIN III) as mild cervical intraepithelial neoplasia (CIN I) on Papanicolaou tests. (12521370)
2003
31
Loop electrosurgical excision procedure in vulvar intraepithelial neoplasia treatment. (17051029)
2002
32
CO2 laser surgery for vulvar intraepithelial neoplasia. Excisional, destructive and combined techniques. (12497680)
2002
33
Vulvar intraepithelial neoplasia treated with cavitational ultrasonic surgical aspiration. (11925129)
2002
34
Photodynamic therapy of vulvar intraepithelial neoplasia III using topically applied 5-aminolevulinic acid. (11136571)
2001
35
Trends in vulvar neoplasia. Increasing incidence of vulvar intraepithelial neoplasia and squamous cell carcinoma of the vulva in young women. (10986677)
2000
36
A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive. (10999722)
2000
37
Human papillomavirus DNA in multicentric vulvar intraepithelial neoplasia. (9475186)
1998
38
Angiogenesis in vulvar intraepithelial neoplasia. (9062159)
1997
39
Increased prevalence of vulvovaginal condyloma and vulvar intraepithelial neoplasia in women infected with the human immunodeficiency virus. (9166302)
1997
40
Trends in squamous cell carcinoma of the vulva: the influence of vulvar intraepithelial neoplasia. (9277660)
1997
41
Clinicopathologic analysis of 370 cases of vulvar intraepithelial neoplasia. Italian Study Group on Vulvar Disease. (8887191)
1996
42
Vulvar intraepithelial neoplasia and vulvar cancer. (8784883)
1996
43
Biologic behavior of vulvar intraepithelial neoplasia. Histologic and clinical parameters. (8383203)
1993
44
Vulvar intraepithelial neoplasia. A clinicopathologic study of 60 cases. (2177508)
1990
45
Prospective randomized trial of topical alpha-interferon (alpha-interferon gels) for the treatment of vulvar intraepithelial neoplasia III. (2182407)
1990
46
Expression of the human papillomavirus type 16 genome in SK-v cells, a line derived from a vulvar intraepithelial neoplasia. (2157796)
1990
47
Unrecognized invasive carcinoma in vulvar intraepithelial neoplasia (VIN). (3410345)
1988
48
Vulvar intraepithelial neoplasia: a report of two cases. (3744920)
1986
49
Vulvar intraepithelial neoplasia (severe atypia and carcinoma in situ). A clinicopathologic analysis of 41 cases. (6088029)
1984
50
Management of vulvar intraepithelial neoplasia by carbon dioxide laser. (6806733)
1982

Variations for Vulvar Intraepithelial Neoplasia

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Expression for genes affiliated with Vulvar Intraepithelial Neoplasia

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Search GEO for disease gene expression data for Vulvar Intraepithelial Neoplasia.

Pathways for genes affiliated with Vulvar Intraepithelial Neoplasia

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GO Terms for genes affiliated with Vulvar Intraepithelial Neoplasia

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Cellular components related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00058298.3BIRC5, CTNNB1, KRT5, RPS6, SOX2

Biological processes related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of neuron apoptotic processGO:004352510.0CTNNB1, TP53
2pituitary gland developmentGO:00219839.9CDH1, SOX2
3replicative senescenceGO:00903999.9TERT, TP53
4cellular protein localizationGO:00346139.9CTNNB1, TP53
5cellular response to indole-3-methanolGO:00716819.8CDH1, CTNNB1
6cellular response to lithium ionGO:00712859.8CDH1, CTNNB1
7T cell differentiation in thymusGO:00330779.7CTNNB1, RPS6
8adherens junction organizationGO:00343329.2CDH1, CTNNB1
9positive regulation of transcription, DNA-templatedGO:00458938.9CDH1, CTNNB1, SOX2, TP53
10negative regulation of gene expressionGO:00106298.8CTNNB1, HAVCR2, TERT

Sources for Vulvar Intraepithelial Neoplasia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet