MCID: VLV044
MIFTS: 46

Vulvar Intraepithelial Neoplasia malady

Categories: Reproductive diseases, Rare diseases

Aliases & Classifications for Vulvar Intraepithelial Neoplasia

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Sources:
30ICD10 via Orphanet, 53Orphanet, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Vulvar Intraepithelial Neoplasia:

Name: Vulvar Intraepithelial Neoplasia 53
Vulval Intraepithelial Neoplasia 67
 
Vulvar Intraepithelial Tumor 53

Classifications:



External Ids:

Orphanet53 ORPHA137583
ICD10 via Orphanet30 D07.1
UMLS via Orphanet68 C0346210

Summaries for Vulvar Intraepithelial Neoplasia

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Wikipedia:70 The term Vulvar intraepithelial neoplasia (VIN) refers to particular changes that can occur in the skin... more...

MalaCards based summary: Vulvar Intraepithelial Neoplasia, also known as vulval intraepithelial neoplasia, is related to cervicitis and vulva cancer, and has symptoms including pruritus and macule. An important gene associated with Vulvar Intraepithelial Neoplasia is TP53 (Tumor Protein P53), and among its related pathways are RHO GTPases activate IQGAPs and Validated transcriptional targets of AP1 family members Fra1 and Fra2. Affiliated tissues include skin, t cells and testes, and related mouse phenotypes are digestive/alimentary and reproductive system.

Related Diseases for Vulvar Intraepithelial Neoplasia

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Diseases related to Vulvar Intraepithelial Neoplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 185)
idRelated DiseaseScoreTop Affiliating Genes
1cervicitis31.2MMP2, MMP9, TIMP1, TIMP2
2vulva cancer11.4
3oral tuberculosis10.7CDH1, TP53
4zellweger-like syndrome without peroxisomal anomalies10.7MMP2, MMP9
5salivary gland adenoid cystic carcinoma10.6CDKN2A, TP53
6pasli disease10.6MMP9, TP53
7pathological gambling10.6MMP1, MMP2, MMP9
8biliary papillomatosis10.6CDKN2A, TP53
9emphysematous cholecystitis10.6MMP1, MMP2, MMP9
10antidepressant or antipsychotic toxicity or dose selection10.6BIRC5, MMP9, TP53
11limb reduction defect10.6MMP1, MMP2, MMP9
12retinal degeneration10.6MMP1, MMP2, MMP9
13pauciarticular onset juvenile idiopathic arthritis10.6MMP1, MMP2, MMP9
14cecum adenoma10.6MMP2, MMP9, TIMP1
15benign hypertensive renal disease10.6MMP1, MMP2, MMP9
16salt and pepper syndrome10.5MMP1, MMP2, TIMP1
17myosin storage myopathy10.5MMP2, MMP9
18melorheostosis10.5MMP1, TIMP1, TIMP2
19split hand split foot malformation autosomal recessive10.5CDKN2A, TP53
20oral lichen planus10.5CDH1, MMP9, TP53
21granulomatous orchitis10.5MMP1, MMP2, TIMP1
22renal pelvis inverted papilloma10.5CDH1, TP53
23malignant struma ovarii10.5MMP2, MMP9, TIMP1
24meningothelial meningioma10.5CTNNB1, MMP2, MMP9
25renal pelvis carcinoma10.5MMP2, MMP9
26x-linked congenital generalized hypertrichosis10.5CDKN2A, TERT, TP53
27glossopharyngeal nerve neoplasm10.5MMP1, MMP9, TIMP1
28renal hypodysplasia10.5CDKN2A, MMP1, TP53
29adult astrocytic tumour10.5MMP2, MMP9, TP53
30subacute monocytic leukemia10.5KRT10, MMP2, MMP9
31hypoglossal nerve neoplasm10.5CDKN2A, SOX2, TP53
32actinic keratosis10.5CDKN2A, TIMP2, TP53
33extrahepatic bile duct adenocarcinoma10.5CDH1, CTNNB1, TP53
34pregnancy adenoma10.4CDH1, KRT5
35keratopathy10.4MMP1, MMP2, TIMP2, TP53
36duodenal somatostatinoma10.4BIRC5, CDKN2A, TP53
37mesenchymoma10.4CDKN2A, KRT10, TP53
38penis carcinoma in situ10.4CDKN2A, MMP2, TP53
39fallopian tube carcinoma10.4CDH1, CDKN2A, TP53
40extraosseous osteosarcoma10.4MMP2, MMP9, TIMP1, TP53
41adenosine monophosphate deaminase 1 deficiency10.4MMP1, MMP2, MMP9, TIMP2
42pulmonary sarcoidosis10.4MMP1, MMP2, MMP9, TIMP1
43periapical granuloma10.4CDH1, CTNNB1, TP53
44gallbladder papillary carcinoma10.4MMP9, TIMP1, TIMP2, TP53
45penis squamous cell carcinoma10.4MMP2, MMP9, TIMP1, TIMP2
46palmoplantar keratosis10.4MMP1, MMP2, MMP9, TIMP1
47schwannomatosis10.4MMP2, MMP9, TIMP1, TIMP2
48classic endocrine tumor of appendix10.4MMP1, MMP9
49cyclotropia10.4MMP2, TIMP1, TIMP2
50adenoid squamous cell carcinoma10.4CDKN2A, TP53

Graphical network of the top 20 diseases related to Vulvar Intraepithelial Neoplasia:



Diseases related to vulvar intraepithelial neoplasia

Symptoms for Vulvar Intraepithelial Neoplasia

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UMLS symptoms related to Vulvar Intraepithelial Neoplasia:


pruritus, macule

Drugs & Therapeutics for Vulvar Intraepithelial Neoplasia

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Drugs for Vulvar Intraepithelial Neoplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Imiquimodapproved, investigationalPhase 2, Phase 313899011-02-657469
Synonyms:
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
1-isobutyl-1H-imidazo(4,5-c)quinolin-4-amine
1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
3M Brand of Imiquimod
4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline
4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
99011-02-6
AC-529
AC1L1N2I
AC1Q4YO9
Aldara
Aldara (TN)
Aldara, Imiquimod
BB_SC-2107
BIDD:GT0859
Beselna
C056493
CHEBI:36704
CHEMBL1282
CID57469
D02500
DB00724
DZ-2636
FT-0080222
HMS2090M14
 
I06-0624
I06-2289
I0747
I5159_SIGMA
IMIQUIMOD
Imiquimod
Imiquimod (JAN/USAN/INN)
Imiquimod [USAN:INN]
Imiquimod acetate
Imiquimodum
LS-178395
MLS000083577
MTD-39
MolPort-002-507-845
NCGC00070736-02
NSC369100
R 837
R-837
S 26308
S-26308
S1211_Selleck
SMR000048307
STK583860
TL8006059
TMX-101
UNII-P1QW714R7M
ZINC19632912
Zartra
Zyclara
imiquimod
2
Aluminum hydroxideapprovedPhase 320121645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
3
MentholapprovedPhase 323532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
4VaccinesPhase 3, Phase 26428
5interferonsPhase 2, Phase 32137
6Adjuvants, ImmunologicPhase 2, Phase 32484
7Interferon InducersPhase 2, Phase 3285
8Aluminum sulfatePhase 387
9AnestheticsPhase 39001
10Immunosuppressive Agents12770

Interventional clinical trials:

(show all 24)
idNameStatusNCT IDPhase
1Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED)CompletedNCT00092521Phase 3
2A Randomized Trial of Surgical Treatments for Vulvar and Vaginal DysplasiaCompletedNCT00394758Phase 3
3ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-TrialCompletedNCT00941252Phase 2, Phase 3
4A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019)CompletedNCT00090220Phase 3
5Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial NeoplasiaRecruitingNCT01861535Phase 3
6Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )VaccineActive, not recruitingNCT01735006Phase 3
7A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent GirlsActive, not recruitingNCT02562508Phase 3
8Long-term Follow-up of Broad Spectrum Human Papillomavirus (HPV) Vaccine Study in Women (V503-021)Active, not recruitingNCT02653118Phase 3
9Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial NeoplasiaNot yet recruitingNCT02875561Phase 3
10Imiquimod Treatment of CIN LesionsTerminatedNCT02329171Phase 3
11Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cancer, or Endometrial CancerTerminatedNCT00577317Phase 3
12Immunevasion of Human Papillomavirus (HPV) in Vulvar Intraepithelial Neoplasia 2/3 and Anogenital Warts and Efficiency and Mechanisms of Imiquimod TreatmentCompletedNCT00941811Phase 2
13The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom PrevalenceCompletedNCT01986725Phase 2
14Dose-Ranging Study of Quadrivalent Human Papillomavirus (HPV) (Types 6,11,16,18) L1 Virus-Like Particle (VLP) Vaccine (V501-007)(COMPLETED)CompletedNCT00365716Phase 2
15Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVINActive, not recruitingNCT02596074Phase 2
16A New Patient Reported Outcome Instrument to Assess Symptom Experience in Women With Vulvar Neoplasms (WOMAN-PRO)Unknown statusNCT01300663
17SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous CondylomaCompletedNCT01676792Early Phase 1
18Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive TherapyCompletedNCT00727636
19GARDASIL™ Vaccine Impact in Population Study (V501-033)CompletedNCT01077856
20Prevalence of Anal Dysplasia and Anal Cancer in Women With Cervical, Vaginal and Vulvar Dysplasia and CancerRecruitingNCT02140021
21Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their PrecursorsRecruitingNCT02735109
22Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval DiseaseRecruitingNCT02223975
23Evaluation of Long-term HPV Vaccine EfficacyEnrolling by invitationNCT01393470
24Colposcopy and High Resolution Anoscopy in Screening For Anal Dysplasia in Patients With Cervical, Vaginal, or Vulvar Dysplasia or CancerWithdrawnNCT01313104

Search NIH Clinical Center for Vulvar Intraepithelial Neoplasia

Genetic Tests for Vulvar Intraepithelial Neoplasia

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Anatomical Context for Vulvar Intraepithelial Neoplasia

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MalaCards organs/tissues related to Vulvar Intraepithelial Neoplasia:

35
Skin, T cells, Testes, Endothelial, Lung

Animal Models for Vulvar Intraepithelial Neoplasia or affiliated genes

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MGI Mouse Phenotypes related to Vulvar Intraepithelial Neoplasia:

40 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.6CDH1, CDKN2A, CTNNB1, KRT5, MMP9, SOX2
2MP:00053898.3CDH1, CDKN2A, CTNNB1, H2AFX, MMP9, SOX2
3MP:00053888.2CDKN2A, CTNNB1, KLRC1, MMP2, MMP9, SOX2
4MP:00053858.0CDH1, CDKN2A, CTNNB1, H2AFX, MMP2, MMP9
5MP:00053797.9BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, RPS6
6MP:00020067.9CDH1, CDKN2A, CTNNB1, H2AFX, MMP1, MMP2
7MP:00053787.4CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2, KRT5
8MP:00053976.9BIRC5, CDKN2A, CTNNB1, H2AFX, HAVCR2, KLRC1
9MP:00107686.6BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
10MP:00053846.4BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
11MP:00053876.1BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
12MP:00053765.4BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, KLRC1

Publications for Vulvar Intraepithelial Neoplasia

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Articles related to Vulvar Intraepithelial Neoplasia:

(show top 50)    (show all 228)
idTitleAuthorsYear
1
Vulvar and Vaginal Cancer, Vulvar Intraepithelial Neoplasia 3 and Vaginal Intraepithelial Neoplasia 3: Experience of a Referral Institute. (27430086)
2016
2
Usual-type vulvar intraepithelial neoplasia: report of a case and its dermoscopic features. (27419656)
2016
3
Type-specific HPV infection correlates with risk of recurrence of vulvar intraepithelial neoplasia usual type. (28006842)
2016
4
Localized amyloidosis of the vulva with and without vulvar intraepithelial neoplasia: report of a series. (25149547)
2014
5
Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival. (25220367)
2014
6
Pathways of vulvar intraepithelial neoplasia and squamous cell carcinoma. (23190170)
2013
7
Focused ultrasound therapy for vulvar intraepithelial neoplasia in a mice model. (23187305)
2013
8
Treatment of vulvar intraepithelial neoplasia with topical 5% imiquimod cream. (23219095)
2013
9
Rapid spontaneous regression of acute-onset vulvar intraepithelial neoplasia 3 in young women: a case series. (22207153)
2012
10
Optical coherence tomography in vulvar intraepithelial neoplasia. (23214182)
2012
11
Vulvar intraepithelial neoplasia (VIN 2/3): comparing clinical outcomes and evaluating risk factors for recurrence. (22867736)
2012
12
Expression pattern of class I histone deacetylases in vulvar intraepithelial neoplasia and vulvar cancer: a tissue microarray study. (22029821)
2011
13
HPV-negative vulvar intraepithelial neoplasia (VIN) with basaloid histologic pattern: an unrecognized variant of simplex (differentiated) VIN. (19730361)
2009
14
Women's perception of the outcome of the surgical management of vulvar intraepithelial neoplasia. (19160655)
2008
15
Women's experiences with vulvar intraepithelial neoplasia. (19012714)
2008
16
A nonsurgical treatment for vulvar intraepithelial neoplasia. (18769666)
2008
17
Imiquimod 5% cream reduced lesion size in vulvar intraepithelial neoplasia. (18836111)
2008
18
Vulvar intraepithelial neoplasia (erythroplasia of Queyrat). (18786281)
2008
19
Langerhans cell density and high-grade vulvar intraepithelial neoplasia in women with human immunodeficiency virus infection. (17576336)
2007
20
Concordance of gross surgical and final fixed margins in vulvar intraepithelial neoplasia 3 and vulvar cancer. (16967630)
2006
21
Synchronous vulvar intraepithelial neoplasia (VIN) of warty type and cervical intraepithelial neoplasia (CIN): case report. (17183865)
2006
22
Use of the female sexual function index in women with vulvar intraepithelial neoplasia. (16809252)
2006
23
p53 immunostaining in lichen sclerosus is related to ischaemic stress and is not a marker of differentiated vulvar intraepithelial neoplasia (d-VIN). (16430473)
2006
24
Vulvar intraepithelial neoplasia: varied signs, varied symptoms: what you need to know. (15777042)
2005
25
Vulvar intraepithelial neoplasia (VIN)--diagnostic and therapeutic challenges. (12807248)
2003
26
Loop electrosurgical excision procedure in vulvar intraepithelial neoplasia treatment. (17051029)
2002
27
Vulvar intraepithelial neoplasia treated with cavitational ultrasonic surgical aspiration. (11925129)
2002
28
Epidemiology, diagnosis and treatment of vulvar intraepithelial neoplasia. (11801875)
2002
29
Photodynamic therapy of vulvar intraepithelial neoplasia III using topically applied 5-aminolevulinic acid. (11136571)
2001
30
Trends in vulvar neoplasia. Increasing incidence of vulvar intraepithelial neoplasia and squamous cell carcinoma of the vulva in young women. (10986677)
2000
31
A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive. (10999722)
2000
32
Immunohistochemical localization of telomerase hTERT protein and analysis of clonality in multifocal vulvar intraepithelial neoplasia. (10989637)
2000
33
The contribution of MIB 1 in the accurate grading of vulvar intraepithelial neoplasia. (10690171)
1999
34
Human papillomavirus DNA in multicentric vulvar intraepithelial neoplasia. (9475186)
1998
35
Differentiating vulvar intraepithelial neoplasia from nonneoplastic epithelial disorders. The toluidine blue test. (9749417)
1998
36
Vulvar intraepithelial neoplasia in women with HIV. (11361951)
1998
37
Pattern of various cytokeratins of normal vulva, vulvar intraepithelial neoplasia (VIN) and vulvar carcinoma]. (9746912)
1998
38
Angiogenesis in vulvar intraepithelial neoplasia. (9062159)
1997
39
Clinicopathologic analysis of 370 cases of vulvar intraepithelial neoplasia. Italian Study Group on Vulvar Disease. (8887191)
1996
40
Vulvar intraepithelial neoplasia and vulvar cancer. (8784883)
1996
41
The natural history of vulvar intraepithelial neoplasia. (7547730)
1995
42
Biologic behavior of vulvar intraepithelial neoplasia. Histologic and clinical parameters. (8383203)
1993
43
Keratin expression in normal vulva, non-neoplastic epithelial disorders, vulvar intraepithelial neoplasia, and invasive squamous cell carcinoma. (1723057)
1991
44
Vulvar intraepithelial neoplasia. A clinicopathologic study of 60 cases. (2177508)
1990
45
Expression of the human papillomavirus type 16 genome in SK-v cells, a line derived from a vulvar intraepithelial neoplasia. (2157796)
1990
46
Combination of surgical excision and carbon dioxide laser vaporization for multifocal vulvar intraepithelial neoplasia. (3348303)
1988
47
Association of human papillomavirus infection and vulvar intraepithelial neoplasia: a morphological and immunohistochemical study of 30 cases. (3030906)
1987
48
Human fibroblast interferon in cervical and vulvar intraepithelial neoplasia associated with papilloma virus infection. (6099344)
1984
49
Management of vulvar intraepithelial neoplasia by carbon dioxide laser. (6806733)
1982
50
Vulvar intraepithelial neoplasia: correlation of nuclear DNA content and the presence of a human papilloma virus (HPV) structural antigen. (6277449)
1982

Variations for Vulvar Intraepithelial Neoplasia

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Expression for genes affiliated with Vulvar Intraepithelial Neoplasia

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Search GEO for disease gene expression data for Vulvar Intraepithelial Neoplasia.

Pathways for genes affiliated with Vulvar Intraepithelial Neoplasia

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Pathways related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

(show all 22)
idSuper pathwaysScoreTop Affiliating Genes
19.9CDH1, CTNNB1
29.8MMP1, MMP2, MMP9
39.8MMP1, MMP9, TIMP2
49.7KRT5, MMP1, TP53
59.7CDH1, CTNNB1, TP53
69.7BIRC5, MMP9, TERT, TP53
7
Show member pathways
9.5BIRC5, CDH1, CTNNB1, TP53
89.5CDH1, CTNNB1, MMP1, TP53
99.5CDH1, CTNNB1, MMP2, MMP9
109.4CDKN2A, CTNNB1, MMP2, TP53
119.4CDKN2A, CTNNB1, TERT, TP53
129.4BIRC5, CDH1, CTNNB1, SOX2
139.3MMP1, MMP2, MMP9, TIMP1, TIMP2
14
Show member pathways
9.3MMP1, MMP2, MMP9, TIMP1, TIMP2
15
Show member pathways
9.3MMP1, RPS6, TIMP1, TP53
169.2CDH1, CTNNB1, MMP2, MMP9, TERT
17
Show member pathways
9.1CDH1, MMP1, MMP2, MMP9, TIMP1, TIMP2
189.1CDH1, CDKN2A, MMP1, MMP2, MMP9, TP53
19
Show member pathways
9.0MMP2, MMP9, TIMP1, TIMP2, VWF
209.0CTNNB1, MMP2, MMP9, RPS6, TP53
218.8BIRC5, CDH1, CTNNB1, MMP1, MMP2, MMP9
228.5BIRC5, CDH1, CDKN2A, CTNNB1, MMP1, MMP2

GO Terms for genes affiliated with Vulvar Intraepithelial Neoplasia

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Cellular components related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1flotillin complexGO:001660010.4CDH1, CTNNB1
2catenin complexGO:001634210.4CDH1, CTNNB1
3apical junction complexGO:004329610.4CDH1, CTNNB1
4proteinaceous extracellular matrixGO:00055789.1MMP1, MMP2, MMP9, TIMP1, TIMP2, VWF
5extracellular exosomeGO:00700626.1CDH1, CTNNB1, H2AFX, HAVCR2, KRT10, KRT5

Biological processes related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of membrane protein ectodomain proteolysisGO:005104510.6TIMP1, TIMP2
2cellular response to indole-3-methanolGO:007168110.2CDH1, CTNNB1
3replicative senescenceGO:009039910.2CDKN2A, TERT, TP53
4collagen catabolic processGO:003057410.1MMP1, MMP2, MMP9
5positive regulation of vascular smooth muscle cell proliferationGO:190470710.0MMP2, MMP9, TERT
6response to cytokineGO:00340979.9CTNNB1, TIMP1, TIMP2
7extracellular matrix disassemblyGO:00226179.3CDH1, MMP1, MMP2, MMP9, TIMP1, TIMP2
8negative regulation of apoptotic processGO:00430668.9BIRC5, MMP9, RPS6, TERT, TIMP1, TP53

Molecular functions related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chaperone bindingGO:00510879.9BIRC5, TP53, VWF
2protease bindingGO:00020209.5TIMP1, TIMP2, TP53, VWF
3protein bindingGO:00055154.0BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2

Sources for Vulvar Intraepithelial Neoplasia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet