MCID: VLV044
MIFTS: 47

Vulvar Intraepithelial Neoplasia malady

Categories: Reproductive diseases, Rare diseases

Aliases & Classifications for Vulvar Intraepithelial Neoplasia

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Sources:
31ICD10 via Orphanet, 54Orphanet, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Vulvar Intraepithelial Neoplasia:

Name: Vulvar Intraepithelial Neoplasia 54
Vulval Intraepithelial Neoplasia 68
 
Vulvar Intraepithelial Tumor 54

Classifications:



External Ids:

Orphanet54 ORPHA137583
ICD10 via Orphanet31 D07.1
UMLS via Orphanet69 C0346210

Summaries for Vulvar Intraepithelial Neoplasia

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Wikipedia:71 The term Vulvar intraepithelial neoplasia (VIN) refers to particular changes that can occur in the skin... more...

MalaCards based summary: Vulvar Intraepithelial Neoplasia, also known as vulval intraepithelial neoplasia, is related to vulva cancer and squamous cell carcinoma, and has symptoms including pruritus and macule. An important gene associated with Vulvar Intraepithelial Neoplasia is TP53 (Tumor Protein P53), and among its related pathways are Hepatitis C and Hepatocellular Carcinoma and RHO GTPases activate IQGAPs. Affiliated tissues include skin, t cells and testes, and related mouse phenotypes are digestive/alimentary and reproductive system.

Related Diseases for Vulvar Intraepithelial Neoplasia

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Diseases related to Vulvar Intraepithelial Neoplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 159)
idRelated DiseaseScoreTop Affiliating Genes
1vulva cancer11.4
2squamous cell carcinoma10.5
3facio skeletal genital syndrome rippberger type10.4MMP2, MMP9
4cervicitis10.4
5linitis plastica10.3CDH1, TP53
6kleptomania10.3MMP1, MMP2, MMP9
7senile atrophy of choroid10.3MMP1, MMP2, MMP9
8linear porokeratosis10.3MMP1, MMP2, MMP9
9clear cell adenofibroma10.3CDKN2A, TP53
10onychocytic matricoma10.3MMP1, MMP2, MMP9
11gallbladder papillomatosis10.3BIRC5, MMP2, TP53
12appendix carcinoid tumor10.3MMP2, MMP9, TIMP1
13statin toxicity10.3BIRC5, MMP9, TP53
14lacrimal gland adenoid cystic carcinoma10.3CDKN2A, TP53
15laryngostenosis10.3MMP1, MMP2, MMP9
16chondrodysplasia punctata, rhizomelic, type 110.3CDH1, MMP9, TIMP1
17zika fever10.3MMP1, MMP2, TIMP1
18spinal meninges cancer10.3CTNNB1, MMP2, MMP9
19lichen sclerosus10.2
20esophageal neuroendocrine tumor10.2CDH1, MMP2, TIMP1
21lower lip cancer10.2BIRC5, MMP2, MMP9
22cervical verrucous carcinoma10.2CDKN2A, KRT10, TP53
23vascular myelopathy10.2CDKN2A, SOX2, TP53
24mitochondrial encephalomyopathy10.2CDKN2A, MMP2, TP53
25charcot-marie-tooth disease type 2n10.2BIRC5, CDKN2A, TERT
26optic nerve neoplasm10.2MMP1, MMP9, TIMP1
27pityriasis rosea10.2CDKN2A, TIMP2, TP53
28schwannomatosis10.2MMP2, MMP9, TIMP1, TIMP2
29central nervous system teratoma10.2MMP1, MMP2, MMP9, TIMP1
30retinal drusen10.2MMP2, MMP9, TIMP1, TIMP2
31breast papillary carcinoma10.2CDH1, MMP2, MMP9, TIMP1
32angiomyoma10.2MMP1, MMP2, TIMP1, TIMP2
33renal oncocytoma10.2MMP1, MMP9, TIMP1, TIMP2
34megalencephaly-capillary malformation-polymicrogyria syndrome, somatic10.2KRT10, KRT5, TP53
35ideomotor apraxia10.2CDH1, CTNNB1, TP53
36histiocytosis10.2MMP1, MMP2, MMP9, TIMP1
37acute tricyclic antidepressant poisoning10.2MMP2, MMP9
38marginal zone b-cell lymphoma10.2CDKN2A, MMP2, MMP9, TP53
39fallopian tube leiomyosarcoma10.2CDH1, CDKN2A, TP53
40lattice corneal dystrophy10.2CDKN2A, MMP2, MMP9, TP53
41spinal cord oligodendroglioma10.2CDKN2A, KRT5, TP53
42puerperal pulmonary embolism10.2MMP2, MMP9, TIMP1, TIMP2
43connective tissue benign neoplasm10.2CDH1, CDKN2A, TP53
44basaloid squamous cell carcinoma10.2CDH1, KRT10, KRT5
45vascular dementia10.2KRT10, MMP2, MMP9
46hepatic flexure cancer10.2CDKN2A, MMP2, TERT, TP53
47hypotrichosis 810.2CDKN2A, MMP2, MMP9, TP53
48subglottis neoplasm10.2CDKN2A, MMP1, MMP2, TIMP2
49pseudo-meigs syndrome10.2CDH1, CDKN2A, CTNNB1
50glucosephosphate isomerase deficiency10.2CDKN2A, MMP2, MMP9, TP53

Graphical network of the top 20 diseases related to Vulvar Intraepithelial Neoplasia:



Diseases related to vulvar intraepithelial neoplasia

Symptoms & Phenotypes for Vulvar Intraepithelial Neoplasia

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UMLS symptoms related to Vulvar Intraepithelial Neoplasia:


pruritus, macule

MGI Mouse Phenotypes related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

41 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.6CDH1, CDKN2A, CTNNB1, KRT5, MMP9, SOX2
2MP:00053898.3CDH1, CDKN2A, CTNNB1, H2AFX, MMP9, SOX2
3MP:00053888.0CDKN2A, CTNNB1, KLRC1, MMP2, MMP9, SOX2
4MP:00053858.0CDH1, CDKN2A, CTNNB1, H2AFX, MMP2, MMP9
5MP:00053797.9BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, RPS6
6MP:00020067.9CDH1, CDKN2A, CTNNB1, H2AFX, MMP1, MMP2
7MP:00053787.4CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2, KRT5
8MP:00053976.9BIRC5, CDKN2A, CTNNB1, H2AFX, HAVCR2, KLRC1
9MP:00107686.6BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
10MP:00053846.4BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
11MP:00053876.1BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2
12MP:00053765.4BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, KLRC1

Drugs & Therapeutics for Vulvar Intraepithelial Neoplasia

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Drugs for Vulvar Intraepithelial Neoplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1VaccinesPhase 4, Phase 3, Phase 26611
2
Imiquimodapproved, investigationalPhase 2, Phase 314099011-02-657469
Synonyms:
1-(2-Methylpropyl)-1H-imidazole[4,5-c]quinoline-4-amine
1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
1-isobutyl-1H-imidazo(4,5-c)quinolin-4-amine
1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
3M Brand of Imiquimod
4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline
4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
99011-02-6
AC-529
AC1L1N2I
AC1Q4YO9
Aldara
Aldara (TN)
Aldara, Imiquimod
BB_SC-2107
BIDD:GT0859
Beselna
C056493
CHEBI:36704
CHEMBL1282
CID57469
D02500
DB00724
DZ-2636
FT-0080222
HMS2090M14
 
I06-0624
I06-2289
I0747
I5159_SIGMA
IMIQUIMOD
Imiquimod
Imiquimod (JAN/USAN/INN)
Imiquimod [USAN:INN]
Imiquimod acetate
Imiquimodum
LS-178395
MLS000083577
MTD-39
MolPort-002-507-845
NCGC00070736-02
NSC369100
R 837
R-837
S 26308
S-26308
S1211_Selleck
SMR000048307
STK583860
TL8006059
TMX-101
UNII-P1QW714R7M
ZINC19632912
Zartra
Zyclara
imiquimod
3
Aluminum hydroxideapprovedPhase 321021645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
4
MentholapprovedPhase 326062216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
5interferonsPhase 2, Phase 32175
6Adjuvants, ImmunologicPhase 2, Phase 32554
7Interferon InducersPhase 2, Phase 3294
8Aluminum sulfatePhase 392
9AnestheticsPhase 39596
10Immunosuppressive Agents13086

Interventional clinical trials:

(show all 29)
idNameStatusNCT IDPhase
1HPV Vaccine Therapy in Interrupting Progression in Patients With High-Grade Vulvar or Anal LesionsNot yet recruitingNCT03051516Phase 4
2Scientific Evaluation of One or Two Doses of the Bivalent or Nonavalent Prophylactic HPV VaccinesNot yet recruitingNCT03180034Phase 4
3Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED)CompletedNCT00092521Phase 3
4A Randomized Trial of Surgical Treatments for Vulvar and Vaginal DysplasiaCompletedNCT00394758Phase 3
5ITIC (Imiquimod Therapy in Cervical Intraepithelial Neoplasia)-TrialCompletedNCT00941252Phase 2, Phase 3
6A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019)CompletedNCT00090220Phase 3
7Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial NeoplasiaRecruitingNCT01861535Phase 3
8Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )VaccineActive, not recruitingNCT01735006Phase 3
9A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent GirlsActive, not recruitingNCT02562508Phase 3
10Imiquimod Treatment of CIN LesionsTerminatedNCT02329171Phase 3
11Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cancer, or Endometrial CancerTerminatedNCT00577317Phase 3
12Immunevasion of Human Papillomavirus (HPV) in Vulvar Intraepithelial Neoplasia 2/3 and Anogenital Warts and Efficiency and Mechanisms of Imiquimod TreatmentCompletedNCT00941811Phase 2
13The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom PrevalenceCompletedNCT01986725Phase 2
14Dose-Ranging Study of Quadrivalent Human Papillomavirus (HPV) (Types 6,11,16,18) L1 Virus-Like Particle (VLP) Vaccine (V501-007)(COMPLETED)CompletedNCT00365716Phase 2
15Pharmacodynamics, Safety/Tolerability and Efficacy of Topical Omiganan in Patients With uVINActive, not recruitingNCT02596074Phase 2
16VGX-3100 Followed by Electroporation Alone or in Combination With Imiquimod for the Treatment of Human Papilloma Virus HPV-16 and/or HPV-18 Related High Grade Squamous Intraepithelial Lesion (HSIL) of the VulvaNot yet recruitingNCT03180684Phase 2
17A New Patient Reported Outcome Instrument to Assess Symptom Experience in Women With Vulvar Neoplasms (WOMAN-PRO)Unknown statusNCT01300663
18SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous CondylomaCompletedNCT01676792Early Phase 1
19Immunogenicity to Human Papillomavirus Vaccine (Gardasil) Among IBD Patients on Immunosuppressive TherapyCompletedNCT00727636
20GARDASIL™ Vaccine Impact in Population Study (V501-033)CompletedNCT01077856
21Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial NeoplasiaRecruitingNCT02875561
22Prevalence of Anal Dysplasia and Anal Cancer in Women With Cervical, Vaginal and Vulvar Dysplasia and CancerRecruitingNCT02140021
23Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their PrecursorsRecruitingNCT02735109
24Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval DiseaseRecruitingNCT02223975
25Long-term Follow-up of Broad Spectrum Human Papillomavirus (HPV) Vaccine Study in Women (V503-021)Active, not recruitingNCT02653118
26Evaluation of Long-term HPV Vaccine EfficacyEnrolling by invitationNCT01393470
27Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer.Not yet recruitingNCT03061435
28Human Papillomavirus and Cervical Dysplasia in Women With Cystic FibrosisNot yet recruitingNCT03052556
29Colposcopy and High Resolution Anoscopy in Screening For Anal Dysplasia in Patients With Cervical, Vaginal, or Vulvar Dysplasia or CancerWithdrawnNCT01313104

Search NIH Clinical Center for Vulvar Intraepithelial Neoplasia

Genetic Tests for Vulvar Intraepithelial Neoplasia

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Anatomical Context for Vulvar Intraepithelial Neoplasia

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MalaCards organs/tissues related to Vulvar Intraepithelial Neoplasia:

36
Skin, T cells, Testes, Endothelial, Lung

Publications for Vulvar Intraepithelial Neoplasia

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Articles related to Vulvar Intraepithelial Neoplasia:

(show top 50)    (show all 228)
idTitleAuthorsYear
1
Committee Opinion No. 675: Management of Vulvar Intraepithelial Neoplasia: Correction. (28092302)
2017
2
The Natural History of Vulvar Intraepithelial Neoplasia, Differentiated Type: Evidence for Progression and Diagnostic Challenges. (26974999)
2016
3
Committee Opinion No.675: Management of Vulvar Intraepithelial Neoplasia. (27661656)
2016
4
Extra-Genital Bowen's Disease on Abdomen Co-existing with Vulvar Intraepithelial Neoplasia. (27298533)
2016
5
Vulvar intraepithelial neoplasia grade 3 associated with BehAset's disease. (26983442)
2016
6
Differentiated Vulvar Intraepithelial Neoplasia: What Criteria Do We Use in Practice? (27105329)
2016
7
Distinguishing Erosive Lichen Planus From Differentiated Vulvar Intraepithelial Neoplasia. (26796658)
2016
8
Type-specific HPV infection correlates with risk of recurrence of vulvar intraepithelial neoplasia usual type. (28006842)
2016
9
Assessment of CK17 as a Marker for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia. (27513074)
2016
10
Medical and Surgical Treatments for Usual-Type Vulvar Intraepithelial Neoplasia. (27490514)
2016
11
Vulvar intraepithelial neoplasia: clinical presentation, management and outcomes in women infected with HIV. (26959352)
2016
12
Vulvar and Vaginal Cancer, Vulvar Intraepithelial Neoplasia 3 and Vaginal Intraepithelial Neoplasia 3: Experience of a Referral Institute. (27430086)
2016
13
Usual-type vulvar intraepithelial neoplasia: report of a case and its dermoscopic features. (27419656)
2016
14
MALDI Mass Spectrometry Imaging Reveals Decreased CK5 Levels in Vulvar Squamous Cell Carcinomas Compared to the Precursor Lesion Differentiated Vulvar Intraepithelial Neoplasia. (27399691)
2016
15
Committee Opinion No. 675 Summary: Management of Vulvar Intraepithelial Neoplasia. (27661648)
2016
16
Dermoscopic findings of vulvar intraepithelial neoplasia (VIN): a series of 4 cases. (27291788)
2016
17
No viral association found in a set of differentiated vulvar intraepithelial neoplasia cases by human papillomavirus and pan-viral microarray testing. (25894343)
2015
18
Imiquimod in cervical, vaginal and vulvar intraepithelial neoplasia: A review. (26335596)
2015
19
LASER VAPORIZATION IN VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), VAGINAL INTRAEPITHELIAL NEOPLASIA (VAIN) AND CONDYLOMATA ACUMINATA: IGCS-0093 Vulvar and Vaginal Cancer. (25955950)
2015
20
Efficacy of 5% imiquimod cream on vulvar intraepithelial neoplasia in Korea: pilot study. (25673934)
2015
21
Vulvar Intraepithelial Neoplasia (VIN) and Condylomata. (26133495)
2015
22
Localized amyloidosis of the vulva with and without vulvar intraepithelial neoplasia: report of a series. (25149547)
2014
23
Alterations in classical and nonclassical HLA expression in recurrent and progressive HPV-induced usual vulvar intraepithelial neoplasia and implications for immunotherapy. (24415578)
2014
24
Surgical treatment of usual type vulvar intraepithelial neoplasia: a study at three academic hospitals. (24534242)
2014
25
Vulvar intraepithelial neoplasia. (25106700)
2014
26
Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence-free survival. (25220367)
2014
27
An update on vulvar intraepithelial neoplasia: terminology and a practical approach to diagnosis. (24399036)
2014
28
Aberrant staining patterns of E-cadherin and I^-catenin: a potential diagnostic value for distinguishing vulvar intraepithelial neoplasia from non-neoplastic vulvar lesions. (23826417)
2013
29
Quality of life and female sexual function after skinning vulvectomy with split-thickness skin graft in women with vulvar intraepithelial neoplasia or vulvar Paget disease. (24090498)
2013
30
Pathways of vulvar intraepithelial neoplasia and squamous cell carcinoma. (23190170)
2013
31
Treatment of vulvar intraepithelial neoplasia with CO(2) laser vaporization and excision surgery. (23609594)
2013
32
Coexisting high-grade vulvar intraepithelial neoplasia (VIN) and condyloma acuminatum: independent lesions due to different HPV types occurring in immunocompromised patients. (23026935)
2013
33
Immunohistochemical expression of SOX2 in vulvar intraepithelial neoplasia and squamous cell carcinoma. (23518916)
2013
34
The use of argon beam coagulation in treating vulvar intraepithelial neoplasia III: a retrospective review. (23887037)
2013
35
Fascin and cyclin D1 immunoreactivity in non-neoplastic vulvar squamous epithelium, vulvar intraepithelial neoplasia and invasive squamous carcinoma: correlation with Ki67 and p16 protein expression. (24218024)
2013
36
Clinical characteristics associated with development of recurrence and progression in usual-type vulvar intraepithelial neoplasia. (24257562)
2013
37
Phosphorylated S6 as an immunohistochemical biomarker of vulvar intraepithelial neoplasia. (23765247)
2013
38
Safety and efficacy of topical cidofovir to treat high-grade perianal and vulvar intraepithelial neoplasia in HIV-positive men and women. (23032420)
2013
39
Treatment of vulvar intraepithelial neoplasia with topical 5% imiquimod cream. (23219095)
2013
40
Focused ultrasound therapy for vulvar intraepithelial neoplasia in a mice model. (23187305)
2013
41
Interobserver variability and the effect of education in the histopathological diagnosis of differentiated vulvar intraepithelial neoplasia. (23370772)
2013
42
Rapid spontaneous regression of acute-onset vulvar intraepithelial neoplasia 3 in young women: a case series. (22207153)
2012
43
Human papillomavirus distribution in vulvar intraepithelial neoplasia. (22300742)
2012
44
Optical coherence tomography in vulvar intraepithelial neoplasia. (23214182)
2012
45
Prevalence of human papillomavirus types in invasive vulvar cancers and vulvar intraepithelial neoplasia 3 in the United States before vaccine introduction. (22652576)
2012
46
Treatment failure in patients with HPV 16-induced vulvar intraepithelial neoplasia: understanding different clinical responses to immunotherapy. (22913259)
2012
47
Management of vulvar intraepithelial neoplasia. (22020407)
2012
48
Photodynamic therapy of vulvar intraepithelial neoplasia using methyl aminolevulinate. (21254852)
2012
49
CO2 laser total superficial vulvectomy: an outpatient treatment for wide multifocal vulvar intraepithelial neoplasia grade 3. (23084682)
2012
50
A multicenter study of the clinical characteristics of usual-type vulvar intraepithelial neoplasia in China. (22261126)
2012

Variations for Vulvar Intraepithelial Neoplasia

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Expression for genes affiliated with Vulvar Intraepithelial Neoplasia

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Search GEO for disease gene expression data for Vulvar Intraepithelial Neoplasia.

Pathways for genes affiliated with Vulvar Intraepithelial Neoplasia

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Pathways related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

(show all 36)
idSuper pathwaysScoreTop Affiliating Genes
19.9BIRC5, MMP1, TP53
29.9CDH1, CTNNB1
39.8MMP1, MMP2, MMP9
49.8MMP1, MMP9, TIMP2
59.8MMP9, TIMP1, TIMP2
69.8BIRC5, CDKN2A, TP53
79.8CDKN2A, MMP2, TP53
89.7KRT5, MMP1, TP53
99.7CDH1, CTNNB1, TP53
109.7BIRC5, MMP9, TERT, TP53
11
Show member pathways
9.6BIRC5, MMP1, MMP2, MMP9
129.6MMP2, MMP9, TERT, TIMP1
139.5CTNNB1, MMP2, MMP9, TP53
14
Show member pathways
9.5BIRC5, CDH1, CTNNB1, TP53
159.5CDH1, CTNNB1, MMP1, TP53
169.5CDH1, CTNNB1, MMP2, MMP9
179.4CDKN2A, CTNNB1, MMP2, TP53
189.4CDKN2A, CTNNB1, TERT, TP53
199.4BIRC5, CDH1, CTNNB1, SOX2
209.3MMP1, MMP2, MMP9, TIMP1, TIMP2
21
Show member pathways
9.3MMP1, MMP2, MMP9, TIMP1, TIMP2
22
Show member pathways
9.3MMP1, RPS6, TIMP1, TP53
23
Show member pathways
9.3BIRC5, CTNNB1, MMP2, TIMP1, TP53
24
Show member pathways
9.3CDH1, CTNNB1, MMP2, MMP9, TP53
259.2CDH1, CTNNB1, MMP2, MMP9, TERT
26
Show member pathways
9.1CDH1, MMP1, MMP2, MMP9, TIMP1, TIMP2
27
Show member pathways
9.1CDH1, CDKN2A, MMP1, MMP2, MMP9, TP53
28
Show member pathways
9.0MMP2, MMP9, TIMP1, TIMP2, VWF
299.0CTNNB1, MMP2, MMP9, RPS6, TP53
308.9BIRC5, MMP1, MMP2, MMP9, SOX2, TIMP1
318.8BIRC5, CDH1, CTNNB1, MMP1, MMP2, MMP9
328.5BIRC5, CDH1, CDKN2A, CTNNB1, MMP1, MMP2
33
Show member pathways
8.4CDH1, CDKN2A, CTNNB1, MMP2, MMP9, RPS6
34
Show member pathways
8.0BIRC5, HAVCR2, MMP1, MMP2, MMP9, SOX2
35
Show member pathways
6.8CTNNB1, H2AFX, KRT10, KRT5, KRT7, MMP2
36
Show member pathways
6.7BIRC5, CDH1, CTNNB1, HAVCR2, KLRC1, MMP1

GO Terms for genes affiliated with Vulvar Intraepithelial Neoplasia

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Cellular components related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1catenin complexGO:001634210.6CDH1, CTNNB1
2flotillin complexGO:001660010.5CDH1, CTNNB1
3extracellular matrixGO:00310129.5MMP1, MMP2, MMP9, TIMP1, TIMP2, VWF
4proteinaceous extracellular matrixGO:00055788.8MMP1, MMP2, MMP9, TIMP1, TIMP2, VWF
5extracellular exosomeGO:00700626.8CDH1, CTNNB1, H2AFX, HAVCR2, KRT10, KRT5

Biological processes related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of membrane protein ectodomain proteolysisGO:005104510.6TIMP1, TIMP2
2negative regulation of metallopeptidase activityGO:190504910.6TIMP1, TIMP2
3cellular response to indole-3-methanolGO:007168110.6CDH1, CTNNB1
4entry of bacterium into host cellGO:003563510.6CDH1, CTNNB1
5collagen catabolic processGO:003057410.5MMP1, MMP2, MMP9
6positive regulation of vascular smooth muscle cell proliferationGO:190470710.1MMP2, MMP9, TERT
7positive regulation of MAPK cascadeGO:004341010.0CTNNB1, SOX2, TIMP2
8extracellular matrix disassemblyGO:00226179.8CDH1, MMP1, MMP2, MMP9, TIMP1, TIMP2
9replicative senescenceGO:00903999.7CDKN2A, TERT, TP53
10negative regulation of apoptotic processGO:00430669.5BIRC5, MMP9, RPS6, TERT, TIMP1, TP53
11positive regulation of apoptotic processGO:00430659.4CDKN2A, CTNNB1, MMP9, RPS6, TP53

Molecular functions related to Vulvar Intraepithelial Neoplasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chaperone bindingGO:005108710.2BIRC5, TERT, TP53, VWF
2protease bindingGO:000202010.1TIMP1, TIMP2, TP53, VWF
3protein bindingGO:00055154.0BIRC5, CDH1, CDKN2A, CTNNB1, H2AFX, HAVCR2

Sources for Vulvar Intraepithelial Neoplasia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet