Aliases & Classifications for Vulvitis

Summaries for Vulvitis

MalaCards based summary : Vulvitis is related to alcoholic neuropathy and camptodactyly vertebral fusion, and has symptoms including pruritus vulvae An important gene associated with Vulvitis is NXN (Nucleoredoxin), and among its related pathways/superpathways is B Cell Development Pathways. The drugs Acetylcholine and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include testes.

Wikipedia : 71 Vulvitis is inflammation of the vulva, the external female mammalian genitalia that include the labia... more...

Related Diseases for Vulvitis

Diseases related to Vulvitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 105)
id Related Disease Score Top Affiliating Genes
1 alcoholic neuropathy 10.3 CD40LG CD79A
2 camptodactyly vertebral fusion 10.3 CD40LG CD79A
3 spinal polio 10.3 CD40LG CD79A
4 rabies 10.3 CD40LG CD79A
5 unilateral retinoblastoma 10.3 CD40LG CD79A
6 mesangial proliferative glomerulonephritis 10.3 CD40LG CD79A
7 delta chain disease 10.3 CD40LG CD79A
8 discitis 10.3 CD40LG CD79A
9 spinal canal and spinal cord meningioma 10.3 CD40LG CD79A
10 trichostrongyloidiasis 10.3 CD40LG CD79A
11 colloid adenoma 10.3 CD40LG CD79A
12 diabetic peripheral angiopathy 10.3 CD40LG MRAP
13 heart septal defect 10.3 CD40LG CD79A
14 cutaneous polyarteritis nodosa 10.3 CD40LG CD79A
15 mild pre-eclampsia 10.3 CD40LG CD79A
16 retinal microaneurysm 10.3 CD40LG CD79A
17 toxic shock syndrome 10.3 ELANE MRAP
18 tonsil cancer 10.3 CD40LG CD79A
19 indomethacin antenatal infection 10.3 CD40LG CD79A
20 postcricoid region cancer 10.3 CD40LG CD79A
21 beach ear 10.3 CD40LG CD79A
22 acute kidney tubular necrosis 10.3 CD40LG CD79A
23 jaw cancer 10.3 CD40LG MPO
24 angiolipoma 10.3 CD40LG MRAP
25 atheroembolism of kidney 10.3 CD40LG CD79A
26 partial sensory epilepsy 10.3 CD40LG CD79A
27 ritscher-schinzel syndrome 1 10.2 CD40LG CD79A
28 diabetic angiopathy 10.2 CD40LG CD79A
29 muscular dystrophy 10.2 CD40LG CD79A
30 fallopian tube adenomatoid tumor 10.2 MPO MRAP
31 dancing eyes-dancing feet syndrome 10.2 ELANE MPO
32 cannabis dependence 10.2 CD40LG MPO
33 endocarditis 10.2 CD40LG CD79A HSF4
34 perinatal necrotizing enterocolitis 10.2 CD40LG CD79A GYPC
35 dumping syndrome 10.2 CD40LG CD79A
36 primary thrombocytopenia 10.2 CD40LG CD79A MRAP
37 primary lacrimal atrophy 10.2 CD40LG CD79A MRAP
38 striatonigral degeneration 10.2 CD40LG CD79A
39 basilar artery occlusion 10.2 CD40LG CD79A MRAP
40 vulvovaginal candidiasis 10.2 CD40LG CD79A MRAP
41 hairy tongue 10.2 CD40LG CD79A MRAP
42 tularemia 10.2 CD40LG CD79A MRAP
43 intravascular angioleiomyoma 10.2 CD40LG CD79A MRAP
44 conjunctival vascular disease 10.2 CD40LG CD79A MRAP
45 subacute glomerulonephritis 10.2 CD79A ELANE MPO
46 anthracosis 10.2 CD40LG CD79A MRAP
47 hemangioma of orbit 10.2 CD40LG CD79A ELANE
48 newcastle disease 10.2 CD40LG CD79A MRAP
49 lacrimal gland carcinoma 10.2 CD40LG CD79A CR2
50 celiac disease 10.2 CD40LG CD79A MRAP

Graphical network of the top 20 diseases related to Vulvitis:



Diseases related to Vulvitis

Symptoms & Phenotypes for Vulvitis

UMLS symptoms related to Vulvitis:


pruritus vulvae

Drugs & Therapeutics for Vulvitis

Drugs for Vulvitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 97)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 4,Phase 3 51-84-3 187
2
Clotrimazole Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 23593-75-1 2812
3
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
4 Dequalinium Approved Phase 4 6707-58-0
5
Fluconazole Approved Phase 4,Phase 3,Phase 2 86386-73-4 3365
6
Terconazole Approved Phase 4 67915-31-5 441383
7
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 1 137-58-6 3676
8 abobotulinumtoxinA Phase 4,Phase 3
9 Botulinum Toxins Phase 4,Phase 3
10 Botulinum Toxins, Type A Phase 4,Phase 3
11 Cholinergic Agents Phase 4,Phase 3
12 incobotulinumtoxinA Phase 4,Phase 3
13 Neurotransmitter Agents Phase 4,Phase 3
14 onabotulinumtoxinA Phase 4,Phase 3
15 Antifungal Agents Phase 4,Phase 3,Phase 2
16 Anti-Infective Agents Phase 4,Phase 3,Phase 2
17 Anti-Infective Agents, Local Phase 4,Phase 3
18 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3,Phase 2
19 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 3
20 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
21 Hormone Antagonists Phase 4,Phase 3,Phase 2
22 Hormones Phase 4,Phase 3,Phase 2
23 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
24 Steroid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
25 Anesthetics Phase 4,Phase 2,Phase 1
26 Anesthetics, Local Phase 4,Phase 2,Phase 1
27 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 1
28 Central Nervous System Depressants Phase 4,Phase 2,Phase 1
29 Diuretics, Potassium Sparing Phase 4,Phase 2,Phase 1
30 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
31 Sodium Channel Blockers Phase 4,Phase 2,Phase 1
32
Nifedipine Approved Phase 3 21829-25-4 4485
33
Milnacipran Approved Phase 3 92623-85-3 65833
34
Butoconazole Approved Phase 3 64872-77-1, 64872-76-0 47472
35
Clindamycin Approved, Vet_approved Phase 3 18323-44-9 29029
36
Amphotericin B Approved, Investigational Phase 3,Phase 2 1397-89-3 14956 5280965
37
Ketoconazole Approved, Investigational Phase 3 65277-42-1 47576 3823
38
Tetracycline Approved, Vet_approved Phase 3 60-54-8 5353990
39
Capsaicin Approved Phase 2, Phase 3,Phase 1 404-86-4 1548943
40
Acetaminophen Approved Phase 2, Phase 3 103-90-2 1983
41 calcium channel blockers Phase 3,Phase 2
42 Calcium, Dietary Phase 3,Phase 2
43 Tocolytic Agents Phase 3
44 Vasodilator Agents Phase 3
45 Adrenergic Agents Phase 3
46 Antidepressive Agents Phase 3
47 Neurotransmitter Uptake Inhibitors Phase 3
48 Psychotropic Drugs Phase 3,Phase 2
49
Serotonin Phase 3 50-67-9 5202
50 Serotonin Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 76)
id Name Status NCT ID Phase
1 Botox on Vulvar Vestibulitis Unknown status NCT00119886 Phase 4
2 Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis Completed NCT02248506 Phase 4
3 Comparative Efficacy Study of 10 mg Dequalinium Chloride (Fluomizin) in the Treatment of Vulvovaginal Candidiasis Completed NCT02242695 Phase 4
4 Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasis Completed NCT02180828 Phase 4
5 Terconazole Vaginal Suppository vs Fluconazole for the Treatment of Severe Vulvovaginal Candidiasis Completed NCT02180100 Phase 4
6 Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina Completed NCT00194324 Phase 4
7 Study to Compare the Efficacy of Cognitive-behavioral Couple Therapy and Lidocaine for Provoked Vestibulodynia Recruiting NCT01935063 Phase 4
8 Dysbiosis in Localized Provoked Vulvodynia (LPV) Unknown status NCT02393911 Phase 3
9 Efficacy Study of Topical Application of Nifedipine Cream to Treat Vulvar Vestibulitis Completed NCT00496184 Phase 3
10 Savella in Treatment for Provoked Vestibulodynia Completed NCT01304589 Phase 3
11 Vaginal Infection Study Completed NCT00616330 Phase 3
12 Study of the Efficacy and Tolerance of Intra-vaginal Treatment With a Total Freeze-dried Culture of Lcr Regenerans® in the Prevention of Relapses of Recurrent Vulvovaginal Candidiasis Completed NCT02251093 Phase 3
13 The Study Of Fluconazole For Vulvovaginal Candidiasis Completed NCT01806623 Phase 3
14 A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077) Completed NCT01293643 Phase 3
15 Comparative Efficacy of Ovule vs Tablet Completed NCT00755053 Phase 3
16 Diabetes Mellitus and Vulvovaginal Candidiasis Completed NCT00353561 Phase 3
17 A Pilot Study of the Effects of Botulinum Toxin in the Treatment of Provoked Vestibulodynia Recruiting NCT02858219 Phase 3
18 A Study of the Effects of Topical Capsaicin in the Treatment of Provoked Vestibulodynia Recruiting NCT02854670 Phase 2, Phase 3
19 ProF-001_Phase IIa Recruiting NCT03115073 Phase 2, Phase 3
20 Botulinum Toxin A as a Treatment for Provoked Vestibulodynia Not yet recruiting NCT02773641 Phase 3
21 Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Cream. Not yet recruiting NCT03005353 Phase 2, Phase 3
22 Efficacy, Safety LactiSal 1% Gel, LactSal 50 mg, Clotrimazole 100 mg Tablet in Treatment Vulvovaginal Candidiasis Not yet recruiting NCT02907307 Phase 3
23 Phase I/II Randomized, Placebo-Controlled Study of Capsaicin for Interstitial Cystitis and Vulvar Vestibulitis Completed NCT00004316 Phase 1, Phase 2
24 RADIANT: CD101 vs Standard of Care in Subjects With Acute Vaginal Yeast Infections Completed NCT02733432 Phase 2
25 Safety and Efficacy of Oral SCY-078 vs. Oral Fluconazole in Subjects With Vulvovaginal Candidiasis Completed NCT02679456 Phase 2
26 Safety, Tolerability, Immunogenicity and Efficacy of NDV-3A Vaccine in Preventing Recurrent Vulvovaginal Candidiasis Completed NCT01926028 Phase 1, Phase 2
27 A Study to Evaluate Oral VT-1161 in the Treatment of Patients With Acute Vaginal Candidiasis (Yeast Infection) Completed NCT01891331 Phase 2
28 MGCD290 and Fluconazole Versus Fluconazole Alone for the Treatment of Moderate to Severe Vulvovaginal Candidiasis Completed NCT01497223 Phase 2
29 Arasertaconazole Nitrate Pessaries - Dose Finding Study for the Vulvovaginal Candidiasis (VVC) Treatment Completed NCT01144286 Phase 2
30 Safety and Efficacy of Oral Encochleated Amphotericin B (CAMB/MAT2203) in the Treatment of Vulvovaginal Candidiasis (VVC) Recruiting NCT02971007 Phase 2
31 TOL-463 Phase 2 Study for Vaginitis Active, not recruiting NCT02866227 Phase 2
32 A Study to Evaluate Oral VT-1161 in the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection) Active, not recruiting NCT02267382 Phase 2
33 Efficacy and Safety of Oral Encochleated Amphotericin B (CAMB) in the Treatment of Fluconazole-Resistant Vulvovaginal Candidiasis Not yet recruiting NCT03167957 Phase 2
34 Patients With Vulvovaginal Candidiasis Not yet recruiting NCT03024502 Phase 1, Phase 2
35 Pregabalin for the Treatment of Vulvodynia Terminated NCT00853229 Phase 2
36 5% Lidocaine Ointment in the Treatment of Vulvar Vestibulitis Terminated NCT00450242 Phase 2
37 Efficacy Vulvovaginitis Candida Terminated NCT00199264 Phase 2
38 Study Evaluating the Optimal Dosage for Equivalence Between Lcr Regenerans® Capsules and Tablets (Lactobacillus Rhamnosus Lcr35®) on the Vaginal Flora Colonisation Completed NCT02730494 Phase 1
39 Safety and Immunogenicity Study of a Virosomal Vaccine Against Recurrent Vulvovaginal Candida Infection Completed NCT01067131 Phase 1
40 Provoked, Localized Vulvodynia Treatment With Acupuncture and Lidocaine Pilot Study Active, not recruiting NCT01996384 Phase 1
41 Vulvar Vestibulitis Clinical Trial: Desipramine-Lidocaine Completed NCT00276068
42 Effectiveness of Cognitive Behavioural Therapy and Physical Therapy for Provoked Vestibulodynia Completed NCT02494934
43 The Use of Acupuncture for the Treatment of Vulvar Vestibulitis Completed NCT02362763
44 Cold Laser: A Modality to Promote Vulvar Healing and Pain Relief Completed NCT02204319
45 A Search for Helicobacter Pylori in Localized Vulvodynia Completed NCT00501774
46 To Evaluate if the Medication Gabapentin Lessens Vulvar Pain Completed NCT00390013
47 "Vestibulitis Educational Seminar Trial" Study Completed NCT00278850
48 Long-Term Assessment of Quality of Life and Effectiveness of Onabotulinumtoxina Injections in Provoked Vestibulodynia Completed NCT02858375
49 Efficacy of Transcranial Direct-Current Stimulation (tDCS) for Provoked Vestibulodynia : a Triple Blind Randomized Controlled Trial Completed NCT02543593
50 Pregnancy, Childbirth Intentions and Outcomes Under Sexual Pain Completed NCT01731288

Search NIH Clinical Center for Vulvitis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: vulvitis

Genetic Tests for Vulvitis

Anatomical Context for Vulvitis

MalaCards organs/tissues related to Vulvitis:

39
Testes

Publications for Vulvitis

Articles related to Vulvitis:

(show top 50) (show all 123)
id Title Authors Year
1
Successful treatment of intractable vulvitis circumscripta plasmacellularis via combination therapy with topical tacrolimus and tetracycline. ( 27786391 )
2016
2
Case 4: Vulvitis in a nonsexually active adolescent girl. ( 26941554 )
2016
3
Symptoms in plasma cell vulvitis: first observational cohort study on type, frequency and severity. ( 25633048 )
2015
4
Plasma cell vulvitis. ( 26692614 )
2015
5
Comparative study on topical immunomodulatory and anti-inflammatory treatments for plasma cell vulvitis: long-term efficacy and safety. ( 25059818 )
2014
6
Zoon vulvitis as a differential diagnosis in an HIV-infected patient: a short report. ( 23449712 )
2013
7
Longstanding Crohn's vulvitis successfully treated with combined anti-TNFI+ antibody and azathioprine. ( 23815219 )
2013
8
Granulomatous cheilitis with granulomatous vulvitis: a rare association. ( 24177613 )
2013
9
Vulvitis granulomatosa, Melkersson-Rosenthal syndrome, and Crohn's disease: dramatic response to infliximab therapy. ( 22788815 )
2012
10
Plasma cell vulvitis: a vulvar itching dilemma. ( 22421677 )
2012
11
Asymptomatic granulomatous vulvitis and granulomatous cheilitis in childhood: the need for Crohn disease workup. ( 21694543 )
2011
12
Diagnosis and treatment of Zoon's vulvitis. ( 21823840 )
2011
13
Clinical effectiveness of a special silk textile in the treatment of recurrent pediatric inflammatory vulvitis: an open label pilot study. ( 21956267 )
2011
14
Case series of Zoon vulvitis. ( 20040837 )
2010
15
Chronic vulvitis in pre-pubertal girls. ( 20546218 )
2010
16
Vulvitis plasmacellularis circumscripta in pre-existing lichen sclerosus: treatment with imiquimod 5% cream. ( 20542167 )
2010
17
Zoon's vulvitis (vulvitis circumscripta plasmacellularis). ( 20333391 )
2010
18
Idiopathic pustular vulvitis. ( 19778311 )
2009
19
'HPV vulvitis' revisited: frequent and persistent detection of novel epidermodysplasia verruciformis-associated HPV genotypes. ( 18251739 )
2008
20
Ulcerative vulvitis and balanitis in sheep flocks. ( 18641377 )
2008
21
Tacrolimus 0.1% ointment: is it really effective in plasma cell vulvitis? Report of four cases. ( 18182819 )
2008
22
Contact vulvitis due to Pseudowintera Colorata in a topical herbal medicament. ( 17340033 )
2007
23
A case of idiopathic granulomatous cheilitis and vulvitis. ( 17614801 )
2007
24
Extensive mucinous metaplasia of the vulva arising within Zoon's vulvitis. ( 17263821 )
2007
25
Imiquimod treatment of vulvitis circumscripta plasmacellularis. ( 16777111 )
2006
26
Vulvitis circumscripta plasmacellularis: success with a modified treatment regimen using imiquimod. ( 16390720 )
2006
27
Successful treatment of Zoon's vulvitis with high potency topical steroid. ( 15834511 )
2006
28
Ulcerative balanitis and vulvitis of Dorper sheep in South Africa: a study on its aetiology and clinical features. ( 16642715 )
2005
29
In vitro antimicrobial susceptibility of Mycoplasma mycoides mycoides large colony and Arcanobacterium pyogenes isolated from clinical cases of ulcerative balanitis and vulvitis in Dorper sheep in South Africa. ( 16642716 )
2005
30
Retrospective histopathologic reevaluation of 18 cases of plasma cell vulvitis. ( 15730165 )
2005
31
Plasma cell vulvitis: a rare cause of intractable vulvar pruritus. ( 15967935 )
2005
32
Apareunia in a patient with Zoon's vulvitis. ( 16147756 )
2005
33
A case of vulvitis granulomatosa. ( 16361737 )
2005
34
Topical misoprostol therapy for plasma cell vulvitis: a case series. ( 16044059 )
2005
35
Ulcerative vulvitis circumscripta plasmacellularis. ( 14986474 )
2004
36
Idiopathic granulomatous vulvitis. ( 15250899 )
2004
37
Squamous cell carcinoma of the bladder presenting as vulvitis and cliteromegaly. ( 15581990 )
2004
38
Vulvitis granulomatosa and unilateral hypertrophy of the vulva related to Crohn's disease: a case report. ( 15547549 )
2004
39
Are patch tests useful in plasma cell vulvitis? ( 15018438 )
2004
40
Resolution of vulvitis circumscripta plasmacellularis with topical imiquimod: two case reports. ( 14511002 )
2003
41
Ulcerative vulvitis in atypical Reiter's syndrome. ( 12664030 )
2003
42
Plasma cell vulvitis and response to topical steroids: a case report. ( 12935388 )
2003
43
Chronic vulvar purpura: persistent pigmented purpuric dermatitis (lichen aureus) of the vulva or plasma cell (Zoon's) vulvitis? ( 14507407 )
2003
44
Retrospective study of proliferative papillary vulvitis in Florida panthers. ( 11838202 )
2002
45
Re: K. Reddy et al.'s case report on a rare case of plasma cell vulvitis (Zoon's vulvitis). ( 12528723 )
2002
46
Fungal culture findings in cyclic vulvitis. ( 10908782 )
2000
47
Vulvitis circumscripta plasmacellularis mimicking child abuse. ( 10827417 )
2000
48
Vulvitis attributed to hypersensitivity to estrogen. A report of 11 cases. ( 10900584 )
2000
49
A case of vulvitis circumscripta plasmacellularis positive for herpes simplex type II antigen. ( 10233608 )
1998
50
Etretinate: therapy for plasma cell vulvitis. ( 9764673 )
1998

Variations for Vulvitis

Expression for Vulvitis

Search GEO for disease gene expression data for Vulvitis.

Pathways for Vulvitis

Pathways related to Vulvitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.52 CD40LG CR2 TNFRSF8

GO Terms for Vulvitis

Biological processes related to Vulvitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 B cell differentiation GO:0030183 9.33 CD40LG CD79A CR2
2 negative regulation of growth of symbiont in host GO:0044130 9.26 ELANE MPO
3 response to yeast GO:0001878 8.96 ELANE MPO
4 B cell proliferation GO:0042100 8.8 CD40LG CD79A CR2

Sources for Vulvitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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