MCID: VLV010
MIFTS: 49

Vulvovaginitis malady

Summaries for Vulvovaginitis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Vaginitis is an inflammation of the vagina. It can result in discharge, itching and pain, and is often... more...

MalaCards: Vulvovaginitis, also known as vulvovaginitis unspecified, is related to vulvovaginal candidiasis and oral candidiasis. An important gene associated with Vulvovaginitis is MBL2 (mannose-binding lectin (protein C) 2, soluble), and among its related pathways are IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types and Beta defensins. The compounds rantes and estrogen have been mentioned in the context of this disorder. Affiliated tissues include skin, lymph node and colon, and related mouse phenotypes are reproductive system and endocrine/exocrine gland.

Aliases & Classifications for Vulvovaginitis

Sources:
8Disease Ontology, 45Novoseek, 61UMLS, 35MeSH, 57SNOMED-CT, 40NCIt
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Aliases & Descriptions:

vulvovaginitis 8 45 61
vulvovaginitis unspecified 8
vulvovaginitis nos 8
vulvo-vaginitis 8


External Ids:

Disease Ontology8 DOID:2273
MeSH35 D014848
NCIt40 C35131

Related Diseases for Vulvovaginitis

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Vulvovaginitis:



Diseases related to vulvovaginitis

Clinical Features for Vulvovaginitis

Drugs & Therapeutics for Vulvovaginitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Vulvovaginitis

Drug clinical trials:

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Search NIH Clinical Center for Vulvovaginitis

Search CenterWatch for Vulvovaginitis

Genetic Tests for Vulvovaginitis

Anatomical Context for Vulvovaginitis

Sources:
33MalaCards
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MalaCards organs/tissues related to Vulvovaginitis:

33
Skin, Lymph node, Colon, B cells

Animal Models for Vulvovaginitis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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Publications for Vulvovaginitis

Sources:
51PubMed
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Articles related to Vulvovaginitis:

(show top 50)    (show all 301)
idTitleAuthorsYear
1
Microbiological findings of vulvovaginitis in prepubertal girls. (24191064)
2014
2
Association of pregnancy and Candida vaginal colonization in women with or without symptoms of vulvovaginitis. (23689173)
2013
3
Voiding dysfunction: another etiology of vulvovaginitis in young girls. (21600807)
2011
4
Severe vulvovaginitis as a presenting problem of type 2 diabetes in adolescent girls: a case series. (21402639)
2011
5
A new approach in the first-line treatment of bacterial and mycotic vulvovaginitis with topical lipohydroperoxides and glycyrrhetic acid: a comparative study. (21995156)
2011
6
Sample-based assessment of the microbial etiology of bovine necrotic vulvovaginitis. (17553557)
2007
7
Prevalence & susceptibility to fluconazole of Candida species causing vulvovaginitis. (18037716)
2007
8
Necrotic vulvovaginitis in dairy cattle in Israel. (17277301)
2007
9
Prevalence, susceptibility profile and proteinase production of yeasts causing vulvovaginitis in Turkish women. (16519751)
2006
10
Bovine necrotic vulvovaginitis associated with Porphyromonas levii. (15109423)
2004
11
Severe vulvovaginitis associated with intravaginal nystatin therapy. (11483943)
2001
12
Allergic vulvovaginitis in infancy: study of a case. (11674928)
2001
13
Antimicrobial Resistance in Vulvovaginitis. (11722813)
2001
14
Semiquantitative bacterial observations with group B streptococcal vulvovaginitis. (10968592)
2000
15
Systemic treatment of recurrent candidal vulvovaginitis by Itraconazole. (8020181)
1994
16
The identification of Mycoplasma mycoides mycoides LC as the aetiological agent of balanoposthitis and vulvovaginitis in sheep in South Africa. (8392679)
1993
17
Candidal vulvovaginitis. (8435940)
1993
18
Management of vulvovaginitis in pregnancy. (8435943)
1993
19
Vulvovaginitis in the postmenopausal woman. (1472888)
1992
20
Vulvovaginitis: causes and management. (1580682)
1992
21
Streptococcus pyogenes vulvovaginitis in children in Nottingham. (2050200)
1991
22
Antifungal agents vs. boric acid for treating chronic mycotic vulvovaginitis. (1941801)
1991
23
Round table on infectious bovine rhinotracheitis/infectious pustular vulvovaginitis virus infection diagnosis and control. (2402878)
1990
24
Clotrimazole treatment of recurrent and chronic candida vulvovaginitis. (2644595)
1989
25
Study of parasitological causes of vulvovaginitis in Egyptian children. (3418144)
1988
26
Mycology of vulvovaginitis. (3284367)
1988
27
Gonococcal vulvovaginitis among female children in Malaysia. (4035521)
1985
28
Vulvovaginitis caused by Yersinia enterocolitica. (6333675)
1984
29
Management of herpetic vulvovaginitis in pregnancy. (6682572)
1983
30
Vulvovaginitis in children. (6627662)
1983
31
Gonococcal vulvovaginitis in a three-month-old infant. (759060)
1979
32
Pediatric vulvovaginitis. (649456)
1978
33
Paediatric vulvovaginitis. (198910)
1977
34
Pediatric management problems (vulvovaginitis). (1049795)
1976
35
Pathology of Mycoplasma agalactiae induced granular vulvovaginitis (GVV) in goats. (1139959)
1975
36
Meningococcal vulvovaginitis. (4214135)
1974
37
Virus isolations from cases of infectious bovine pustlo-vulvovaginitis and posthitis (IPV/IPB) in cattle in Tanzania. (4378003)
1974
38
The therapy of candida vaginitis and candida vulvovaginitis with a new antimycotic substance, clotrimazole. (4591822)
1973
39
Pediatric vulvovaginitis. (4339058)
1972
40
Gonococcal vulvovaginitis and possible peritonitis in prepubertal girls. (4996392)
1971
41
SEASONAL ALLERGIC VULVOVAGINITIS CAUSED BY POLLEN. (14230735)
1964
42
MYCOTIC VULVOVAGINITIS. INCIDENCE AND PERSISTENCE OF SPECIFIC YEAST SPECIES DURING INFECTION. (14082284)
1963
43
Effects of infectious bovine rhinotracheitis-infectious pustular vulvovaginitis (IBR-IPV) virus on newborn calves. (13796009)
1960
44
Treatment of vulvovaginitis with a new combination of nitrofurans. (13606185)
1959
45
Typhoid fever with vulvovaginitis. (13599478)
1958
46
Trichomonal & monilial vulvovaginitis; its treatment with trichomycin]. (13505585)
1957
47
Nystatin vaginal tablets in the treatment of candidal vulvovaginitis. (13359010)
1956
48
Primary herpetic vulvovaginitis; report of a case; isolation and identification of herpes simplex virus. (14929613)
1952
49
Primary herpetic vulvovaginitis. (20277745)
1946
50
Vulvovaginitis in Children. (20781430)
1938

Genetic Variations for Vulvovaginitis

Expression for genes affiliated with Vulvovaginitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Vulvovaginitis

Search GEO for disease gene expression data for Vulvovaginitis.

Pathways for genes affiliated with Vulvovaginitis

Sources:
53R&D Systems, 54Reactome, 30KEGG, 52QIAGEN
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Compounds for genes affiliated with Vulvovaginitis

Sources:
45Novoseek, 50PharmGKB, 29IUPHAR, 11DrugBank, 24HMDB, 2BitterDB, 60Tocris Bioscience
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Compounds related to Vulvovaginitis according to GeneCards/GeneDecks:

(show top 50)    (show all 83)
idCompoundScoreTop Affiliating Genes
1rantes4510.5MBL2, DEFB4A, IL4
2estrogen4510.4DEFB4A, MBL2, CD79A
3glutamate4510.4LAP3, HSPD1
4acetylcholine45 50 29 11 2414.4GGT1
5tuberculin4510.4CD79A, MBL2, HSPD1
6acetaminophen45 2 50 11 2414.4GGT1, IL13
7hbd24510.4DEFA5, DEFB4A, DEFB1
8cyclosporin a45 29 6012.4CD79A, F2, ACTC1
9polymyxin b4510.4IL4, DEFB1, MBL2, HSPD1
10glucose4510.4DEFB1, LAP3, ACTC1
11reticulin4510.3ACTC1, DES, CD79A
12penicillin4510.3CD79A, F2, IL13
13polysaccharide4510.3CD79A, LAP3, HSPD1, MBL2
14oxazolone4510.2IL13, IL4
15heparin45 29 11 2413.2DEFB4A, DES, CD79A, IL13
16anti-fungal4510.2DEFB4A, CD79A, MBL2, SKAP2
17praziquantel45 1111.2IL4, GGT1, CD79A, IL13
18polyethylene glycol4510.2IL4, CD79A, HSPD1, F2
19mannose4510.1HSPD1, MBL2, DEFB4A, CD79A, IL13
20alpha tocopherol4510.1IL4, IL13, HSPA4
21p-nitroaniline4510.1LAP3, GGT1
22biotin45 11 2412.1IL4, CD79A, ACTC1, DES, HSPD1
23bleomycin45 1111.1IL13, IL4, LAP3, HSPD1
24carbamazepine45 50 1112.1CD79A, IL4, LST1, GGT1
25nickel45 2411.1HSPD1, IL13
26con a4510.0CD79A, MBL2, IL4
27aspartate4510.0SKAP2, HSPA4, MBL2, F2, HSPD1
28azathioprine45 50 2 1113.0IL4, GGT1, DES, CD79A
29hyaluronic acid45 2411.0CD79A, DES, F2, IL13, GGT1
30aspirin45 50 29 2412.9IL4, IL13, CD79A, HSPA4, F2
31fibrinogen459.9MBL2, HSPD1, CD79A, HSPA4, DES, F2
32dexamethasone45 50 29 1112.9IL13, GGT1, CD79A, DEFB4A, DEFB1, HSPA4
33thyroxine45 2410.9MBL2, GGT1, HSPA4, IL4, IL13, CD79A
34n acetylcysteine459.9HSPD1, HSPA4, CD79A, IL4, F2, GGT1
35indomethacin45 60 29 1112.8HSPD1, HSPA4, IL13, IL4, GGT1, CD79A
36ethanol45 50 11 2412.8HSPD1, GGT1, MBL2, DES, LAP3
37h2o2459.8HSPA4, CD79A, HSPD1, DES, LAP3, IL13
38iron45 2410.7LAP3, ACTC1, DES, HSPA4, HSPD1, GGT1
39progesterone45 60 29 11 2413.7ACTC1, HSPA4, MBL2, HSPD1, DEFB4A, DES
40steroid459.7DES, IL13, ACTC1, CD79A, HSPA4, MBL2
41doxorubicin45 50 1111.6HMGA2, HSPA4, HSPD1, IL13, DES
42paraffin459.5HSPD1, HSPA4, MBL2, DEFB4A, DES, CD79A
43dihydrotestosterone45 29 11 2412.5DES, CD79A, IL4, GGT1
44alanine459.5LAP3, GGT1, F2, IL13, HSPD1, CD79A
45lactate459.5CD79A, LAP3, GGT1, F2, HSPA4, HSPD1
46cysteine459.4CD79A, HSPD1, LAP3, DEFB4A, GGT1, IL4
47vegf459.4CD79A, HSPA4, HSPD1, IL13, LAP3, ACTC1
48creatinine459.4LAP3, GGT1, ACTC1, HSPA4, F2, DES
49tyrosine459.3DES, DEFB4A, SKAP2, ACTC1, IL13, IL4
50retinoic acid45 2410.2DES, LAP3, ACTC1, HMGA2, IL13, CD79A

GO Terms for genes affiliated with Vulvovaginitis

Sources:
16Gene Ontology
See all sources

Cellular components related to Vulvovaginitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:0057969.6F2, DEFB4A, DEFB1, DEFA5
2extracellular spaceGO:0056159.5MBL2, DEFA5, IL13, IL4, F2, HSPD1

Biological processes related to Vulvovaginitis according to GeneCards/GeneDecks:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of acute inflammatory responseGO:00267410.3NLRP3, IL4
2regulation of proton transportGO:01015510.3IL4, IL13
3positive regulation of macrophage activationGO:04303210.2HSPD1, IL13
4B cell activationGO:04211310.2SKAP2, CD79A, HSPD1
5negative regulation of astrocyte differentiationGO:04871210.1HMGA2, F2
6defense response to bacteriumGO:04274210.1MBL2, DEFA5, DEFB1, DEFB4A
7response to ethanolGO:04547110.1ACTC1, IL4, IL13
8chaperone-mediated protein complex assemblyGO:05113110.0HSPD1, HSPA4
9B cell proliferationGO:0421009.9HSPD1, CD79A
10innate immune responseGO:0450879.8DEFB4A, DEFB1, DEFA5, MBL2, NLRP3
11immune responseGO:0069559.7IL4, IL13, DEFB4A, DEFB1, HLA-DQB1, LST1

Products for genes affiliated with Vulvovaginitis

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  • Proteins
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  • Antibodies

Sources for Vulvovaginitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet