MCID: VLV010
MIFTS: 47

Vulvovaginitis malady

Reproductive diseases category

Summaries for Vulvovaginitis

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66Wikipedia, 34MalaCards
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Wikipedia:66 Vaginitis is an inflammation of the vagina. It can result in discharge, itching and pain, and is often... more...

MalaCards: Vulvovaginitis, also known as vulvovaginitis unspecified, is related to cervicitis and diabetes mellitus. An important gene associated with Vulvovaginitis is HSPD1 (heat shock 60kDa protein 1 (chaperonin)), and among its related pathways are Validated targets of C-MYC transcriptional activation and Tuberculosis. The compounds cdcl2 and amp-pnp have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and skin, and related mouse phenotypes are reproductive system and nervous system.

Aliases & Classifications for Vulvovaginitis

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9Disease Ontology, 46Novoseek, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


Aliases & Descriptions:

vulvovaginitis 9 46 63
vulvovaginitis unspecified 9
vulvovaginitis nos 9
vulvo-vaginitis 9


External Ids:

Disease Ontology9 DOID:2273
NCIt41 C35131
MeSH36 D014848

Related Diseases for Vulvovaginitis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Vulvovaginitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 90)
idRelated DiseaseScoreTop Affiliating Genes
1cervicitis30.2HSPD1
2diabetes mellitus30.0HSPD1, HSPA4
3type 1 diabetes mellitus29.9IL10, HSPD1
4oral lichen planus29.9HSPD1, HSPA4
5skin disease29.9IL10, HSPA4
6melanoma29.8HSPD1, HSPA4, IL10
7vulvovaginal candidiasis11.2
8candidiasis11.2
9vaginitis10.8
10rhinotracheitis10.6
11bacterial vaginosis10.4
12vulvovaginal gingival syndrome10.4
13lichen planus10.4
14gingivitis10.4
15candida glabrata10.3
16granuloma inguinale10.2
17vaginal cancer10.2
18balanoposthitis10.1
19rhabdomyosarcoma10.1
20vaginal discharge10.1
21vulvovaginal rhabdomyosarcoma10.1
22connective tissue disease10.1IL10
23trachoma10.1HSPD1
24trichomoniasis10.1
25embryonal rhabdomyosarcoma10.1
26influenza10.1
27lichen sclerosus10.1
28blindness10.1
29vulvar intraepithelial neoplasia10.1
30lepromatous leprosy10.0IL10, HSPD1
31paracoccidioidomycosis10.0IL10, HSPD1
32periodontitis10.0IL10, HSPD1
33uveitis10.0IL10, HSPD1
34tetanus10.0HSPD1, IL10
35hypersensitivity reaction type ii disease10.0IL10, HSPD1
36leishmaniasis10.0HSPA4, IL10
37sepsis10.0IL10, HSPD1
38cork-handlers' disease10.0IL10, HSPA4
39pneumonia10.0HSPA4, IL10
40vascular disease10.0HSPA4, IL10
41cataract10.0HSPD1, HSPA4
42ulcerative colitis10.0HSPA4, IL10
43systemic lupus erythematosus10.0HSPD1, IL10
44coronary artery disease10.0HSPD1, HSPA4
45multiple sclerosis10.0IL10, HSPD1
46non-hodgkin lymphoma10.0HSPD1, HSPA4
47congenital heart disease10.0HSPD1, HSPA4
48cerebrovascular disease10.0HSPD1, HSPA4
49arthritis10.0HSPD1, IL10
50hepatitis c9.9HSPD1, IL10, HSPA4

Graphical network of the top 20 diseases related to Vulvovaginitis:



Diseases related to vulvovaginitis

Symptoms for Vulvovaginitis

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Drugs & Therapeutics for Vulvovaginitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Vulvovaginitis

Drug clinical trials:

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Search NIH Clinical Center for Vulvovaginitis

Search CenterWatch for Vulvovaginitis

Genetic Tests for Vulvovaginitis

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Anatomical Context for Vulvovaginitis

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34MalaCards
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MalaCards organs/tissues related to Vulvovaginitis:

34
Testes, Colon, Skin, Ovary, Lymph node, B cells

Animal Models for Vulvovaginitis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Vulvovaginitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.5IL10, HSPA4, HSPD1
2MP:00036318.5IL10, HSPA4, HSPD1
3MP:00053868.4IL10, HSPA4, HSPD1
4MP:00053848.2HSPD1, HSPA4, IL10

Publications for Vulvovaginitis

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Sources:
53PubMed
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Articles related to Vulvovaginitis:

(show top 50)    (show all 634)
idTitleAuthorsYear
1
Prophylactic strategies in recurrent vulvovaginal candidiasis: a 2-year study testing a phytonutrient vs itraconazole. (24152852)
2013
2
Candida nivariensis as an etiologic agent of vulvovaginal candidiasis in a tertiary care hospital of New Delhi, India. (23537782)
2013
3
Diverse vaginal microbiomes in reproductive-age women with vulvovaginal candidiasis. (24265786)
2013
4
Preparation and characterization of mucoadhesive thermoresponsive systems containing propolis for the treatment of vulvovaginal candidiasis. (23334938)
2013
5
Voiding dysfunction: another etiology of vulvovaginitis in young girls. (21600807)
2011
6
Patient preferences and treatment safety for uncomplicated vulvovaginal candidiasis in primary health care. (21281464)
2011
7
Recurrent vulvovaginal candidiasis - current management. (21597520)
2011
8
Vulvovaginitis in childhood. (19884044)
2010
9
Low-grade epithelial-myoepithelial carcinoma of bartholin gland: report of 2 cases of a distinctive neoplasm arising in the vulvovaginal region. (19620948)
2009
10
Granular Vulvovaginitis Syndrome in Nelore pubertal and post pubertal replacement heifers under tropical conditions: role of Mycoplasma spp., Ureaplasma diversum and BHV-1. (19319656)
2009
11
Preliminary evaluation of a vaginal cream containing lactoferrin in the treatment of vulvovaginal candidosis]. (18487962)
2008
12
Vulvovaginal candidiasis: diagnostic and therapeutic approaches used by Dutch general practitioners. (18464170)
2008
13
Prevalence of vulvovaginitis and bacterial vaginosis in patients with koilocytosis. (19274321)
2008
14
Methylrosaniline chloride stained vaginal smears for the diagnosis of vulvovaginal candidiasis. (17904142)
2007
15
Sample-based assessment of the microbial etiology of bovine necrotic vulvovaginitis. (17553557)
2007
16
Fluconazole reduced the rate of recurrence of vulvovaginal candidiasis. (15830422)
2005
17
Risk factors for recurrent vulvovaginal candidiasis in women receiving maintenance antifungal therapy: results of a prospective cohort study. (15041994)
2004
18
"Not thrush again!" Women's experience of post-antibiotic vulvovaginitis. (12831384)
2003
19
Management of patients with recurrent vulvovaginal candidiasis. (12749733)
2003
20
Vulvovaginitis in prepubertal girls. (12651758)
2003
21
Prevention and treatment of vulvovaginal candidiasis using exogenous Lactobacillus. (12774870)
2003
22
Clinical resistance of recurrent Candida albicans vulvovaginitis to fluconazole in the presence and absence of in vitro resistance. (12621787)
2003
23
Vulvovaginal candidiasis. (12228137)
2002
24
Pathogenesis of Recurrent Vulvovaginal Candidiasis. (12433327)
2002
25
Acute glomerulonephritis with group A streptococcal vulvovaginitis. (11156071)
2000
26
Value of Candida polymerase chain reaction and vaginal cytokine analysis for the differential diagnosis of women with recurrent vulvovaginitis. (11220486)
2000
27
Allergic vulvovaginitis. (11061467)
2000
28
Vulvovaginitis: clinical features, aetiology, and microbiology of the genital tract. (10373139)
1999
29
Group B streptococcal vulvovaginitis. (9204033)
1997
30
Clinical and cost considerations in the pharmacotherapy of vulvovaginal candidiasis. (10160477)
1996
31
Role of antifungal drug resistance in the pathogenesis of recurrent vulvovaginal candidiasis. (8912167)
1996
32
The impact of oral contraception on vulvovaginal candidiasis. (7628203)
1995
33
Treatment options for vulvovaginal candidiasis, 1993. (7795112)
1995
34
Systemic treatment of recurrent candidal vulvovaginitis by Itraconazole. (8020181)
1994
35
Vulvovaginitis in the postmenopausal woman. (1472888)
1992
36
Terconazole and miconazole cream for treating vulvovaginal candidiasis. A comparison. (1941796)
1991
37
Pathogenesis of Candida vulvovaginitis. (2688924)
1989
38
Study of parasitological causes of vulvovaginitis in Egyptian children. (3418144)
1988
39
Papers selected from presentations given at the symposium "Vulvovaginal Candidiasis: Current Views". January 10-11, 1987. (3364510)
1988
40
Bleeding and vulvovaginitis in the pediatric age group. (3308254)
1987
41
Candida tropicalis vulvovaginitis. (3895072)
1985
42
Vulvovaginal candidiasis: treatment and recurrence. (6963163)
1982
43
Treatment of fungal vulvovaginitis with Canesten. (751276)
1978
44
Diagnosis of Candida vulvovaginitis. (342550)
1978
45
Vulvovaginal candidiasis treated with clotrimazole cream in seven days compared with fourteen-day treatment with miconazole cream. (360842)
1978
46
Comparative evaluation of Monistat and Mycostatin in the treatment of vulvovaginal candidiasis. (4604245)
1974
47
Combined radical surgery, radiation therapy and chemotherapy in infants with vulvovaginal embryonal rhabdomyosarcoma. (4742656)
1973
48
A passive haemagglutination test for the demonstration of antibody to infectious bovine rhinotracheitis-infectious pustular vulvovaginitis virus. 1. Standardisation of test components. (4798201)
1973
49
Gonococcal vulvovaginitis and possible peritonitis in prepubertal girls. (4996392)
1971
50
Diabetic vulvovaginitis treated with vitamin E suppositories. (13124418)
1954

Variations for Vulvovaginitis

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Expression for genes affiliated with Vulvovaginitis

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Vulvovaginitis

Search GEO for disease gene expression data for Vulvovaginitis.

Pathways for genes affiliated with Vulvovaginitis

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Sources:
51PathCards, 39NCBI BioSystems Database, 31KEGG, 54QIAGEN
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Compounds for genes affiliated with Vulvovaginitis

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46Novoseek, 30IUPHAR, 12DrugBank, 25HMDB, 62Tocris Bioscience, 52PharmGKB, 3BitterDB
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Compounds related to Vulvovaginitis according to GeneCards/GeneDecks:

(show all 48)
idCompoundScoreTop Affiliating Genes
1cdcl2469.8HSPA4, HSPD1
2amp-pnp30 4610.8HSPA4, HSPD1
3sodium arsenite469.7HSPD1, HSPA4
4alpha-ketoglutarate469.7HSPD1, HSPA4
5manganese superoxide469.7HSPA4, HSPD1
6malondialdehyde469.7HSPA4, HSPD1
7neomycin469.7HSPD1, HSPA4
8latex469.7HSPD1, HSPA4
9mannitol46 1210.7HSPD1, HSPA4
10arsenite46 2510.7HSPD1, HSPA4
11polyacrylamide469.6HSPD1, HSPA4
12n acetylcysteine469.6HSPA4, HSPD1
13indomethacin46 30 62 1212.6HSPA4, HSPD1
14nmda46 3010.6HSPD1, HSPA4
15fibrinogen469.6HSPA4, HSPD1
16ketamine46 30 1211.6IL10, HSPA4
17pd 98,059469.6HSPA4, HSPD1
18ibuprofen46 30 52 25 1213.5IL10, HSPA4
1915-deoxy-delta-12,14-prostaglandin j2469.5HSPA4, IL10
204-hydroxynonenal46 2510.5HSPA4, IL10
21doxorubicin46 52 1211.5HSPD1, HSPA4
22chloroquine46 3 52 30 1213.5HSPA4, IL10
23gemcitabine46 52 1211.5HSPA4, IL10
24thyroxine46 2510.5IL10, HSPA4
25p 277469.5HSPD1, IL10
26bifidobacterium469.5IL10, HSPD1
27toxin-1469.5IL10, HSPD1
28quercetin46 62 25 1212.5IL10, HSPA4
29tuberculin469.5HSPD1, IL10
30polymyxin b469.5HSPD1, IL10
31dmso469.5IL10, HSPA4
32glutamine469.4HSPD1, HSPA4
33sb 20358046 6210.4HSPA4, IL10
34iron46 2510.4HSPA4, HSPD1
35biotin46 25 1211.4IL10, HSPD1
36endotoxin469.4HSPD1, IL10
37rantes469.3IL10, HSPD1
38ly294002469.3IL10, HSPA4
39hydrogen46 2510.3HSPA4, HSPD1
40superoxide46 2510.3HSPA4, HSPD1
41fatty acid469.2HSPD1, HSPA4
42cyclosporin a46 30 6211.2IL10, HSPD1
43lactate469.0HSPD1, HSPA4
44paraffin468.9HSPA4, HSPD1, IL10
45aspartate468.9HSPD1, HSPA4, IL10
46cycloheximide468.9HSPD1, HSPA4, IL10
47dexamethasone46 52 30 1211.9HSPA4, IL10, HSPD1
48vegf468.9IL10, HSPA4, HSPD1

GO Terms for genes affiliated with Vulvovaginitis

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17Gene Ontology
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Biological processes related to Vulvovaginitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chaperone-mediated protein complex assemblyGO:0511319.3HSPA4, HSPD1
2response to unfolded proteinGO:0069869.0HSPA4, HSPD1
3negative regulation of apoptotic processGO:0430669.0IL10, HSPD1
4B cell proliferationGO:0421008.9IL10, HSPD1

Products for genes affiliated with Vulvovaginitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Vulvovaginitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet