MCID: VLV010
MIFTS: 48

Vulvovaginitis malady

Reproductive diseases category
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Summaries for Vulvovaginitis

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Wikipedia:65 Vaginitis is an inflammation of the vagina. It can result in discharge, itching and pain, and is often... more...

MalaCards based summary: Vulvovaginitis, also known as vulvovaginitis unspecified, is related to cervicitis and type 1 diabetes mellitus. An important gene associated with Vulvovaginitis is HSPD1 (heat shock 60kDa protein 1 (chaperonin)), and among its related pathways are Validated targets of C-MYC transcriptional activation and Tuberculosis. The compounds cdcl2 and amp-pnp have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and skin, and related mouse phenotypes are reproductive system and nervous system.

Aliases & Classifications for Vulvovaginitis

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Sources:
8Disease Ontology, 44Novoseek, 62UMLS, 57SNOMED-CT, 34MeSH, 39NCIt
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Vulvovaginitis, Aliases & Descriptions:

Name: Vulvovaginitis 8 44 62
Vulvovaginitis Unspecified 8
 
Vulvovaginitis Nos 8
Vulvo-Vaginitis 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


External Ids:

Disease Ontology8 DOID:2273
MeSH34 D014848
NCIt39 C35131

Related Diseases for Vulvovaginitis

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Diseases related to Vulvovaginitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1cervicitis30.7HSPD1
2type 1 diabetes mellitus30.1IL10, HSPD1
3oral lichen planus29.9HSPA4, HSPD1
4skin disease29.9IL10, HSPA4
5diabetes mellitus29.9HSPA4, HSPD1
6melanoma29.5IL10, HSPA4, HSPD1
7vulvovaginal candidiasis11.2
8candidiasis11.2
9vaginitis10.8
10rhinotracheitis10.6
11bacterial vaginosis10.4
12vulvovaginal gingival syndrome10.4
13lichen planus10.4
14connective tissue disease10.4IL10
15gingivitis10.4
16vaginal cancer10.4
17trachoma10.4HSPD1
18candida glabrata10.3
19granuloma inguinale10.2
20balanoposthitis10.2
21rhabdomyosarcoma10.2
22vaginal discharge10.2
23vulvovaginal rhabdomyosarcoma10.2
24lepromatous leprosy10.1IL10, HSPD1
25paracoccidioidomycosis10.1IL10, HSPD1
26periodontitis10.1HSPD1, IL10
27uveitis10.1IL10, HSPD1
28tetanus10.1IL10, HSPD1
29hypersensitivity reaction type ii disease10.1IL10, HSPD1
30trichomoniasis10.1
31embryonal rhabdomyosarcoma10.1
32lichen sclerosus10.1
33blindness10.1
34vulvar intraepithelial neoplasia10.1
35leishmaniasis10.0HSPA4, IL10
36sepsis10.0HSPD1, IL10
37cork-handlers' disease10.0HSPA4, IL10
38pneumonia10.0IL10, HSPA4
39vascular disease10.0HSPA4, IL10
40cataract10.0HSPA4, HSPD1
41systemic lupus erythematosus10.0HSPD1, IL10
42ulcerative colitis10.0IL10, HSPA4
43coronary artery anomaly9.9HSPD1, HSPA4
44multiple sclerosis9.9IL10, HSPD1
45deficiency anemia9.9
46cystic fibrosis9.9
47glomerulonephritis9.9
48graft versus host disease9.9
49hematopoietic stem cell transplantation9.9
50stevens-johnson syndrome9.9

Graphical network of the top 20 diseases related to Vulvovaginitis:



Diseases related to vulvovaginitis

Symptoms for Vulvovaginitis

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Drugs & Therapeutics for Vulvovaginitis

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Drug clinical trials:

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Search NIH Clinical Center for Vulvovaginitis

Genetic Tests for Vulvovaginitis

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Anatomical Context for Vulvovaginitis

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MalaCards organs/tissues related to Vulvovaginitis:

32
Testes, Colon, Skin, Lymph node, Breast, Ovary, B cells, Neutrophil

Animal Models for Vulvovaginitis or affiliated genes

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MGI Mouse Phenotypes related to Vulvovaginitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.5IL10, HSPA4, HSPD1
2MP:00036318.5IL10, HSPA4, HSPD1
3MP:00053868.4IL10, HSPA4, HSPD1
4MP:00053848.2HSPD1, HSPA4, IL10

Publications for Vulvovaginitis

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Articles related to Vulvovaginitis:

(show top 50)    (show all 661)
idTitleAuthorsYear
1
Comment on "Vulvovaginal Candidiasis as a Chronic Disease: Diagnostic Criteria and Definition" (24769654)
2014
2
Mannose-binding lectin codon 54 gene polymorphism and vulvovaginal candidiasis: a systematic review and meta-analysis. (25143944)
2014
3
Determinants of symptomatic vulvovaginal candidiasis among human immunodeficiency virus type 1 infected women in rural KwaZulu-Natal, South Africa. (24812479)
2014
4
Prophylactic strategies in recurrent vulvovaginal candidiasis: a 2-year study testing a phytonutrient vs itraconazole. (24152852)
2013
5
Candida nivariensis as an etiologic agent of vulvovaginal candidiasis in a tertiary care hospital of New Delhi, India. (23537782)
2013
6
Diverse vaginal microbiomes in reproductive-age women with vulvovaginal candidiasis. (24265786)
2013
7
Preparation and characterization of mucoadhesive thermoresponsive systems containing propolis for the treatment of vulvovaginal candidiasis. (23334938)
2013
8
Voiding dysfunction: another etiology of vulvovaginitis in young girls. (21600807)
2011
9
Patient preferences and treatment safety for uncomplicated vulvovaginal candidiasis in primary health care. (21281464)
2011
10
Recurrent vulvovaginal candidiasis - current management. (21597520)
2011
11
Vulvovaginitis in childhood. (19884044)
2010
12
Low-grade epithelial-myoepithelial carcinoma of bartholin gland: report of 2 cases of a distinctive neoplasm arising in the vulvovaginal region. (19620948)
2009
13
Granular Vulvovaginitis Syndrome in Nelore pubertal and post pubertal replacement heifers under tropical conditions: role of Mycoplasma spp., Ureaplasma diversum and BHV-1. (19319656)
2009
14
Preliminary evaluation of a vaginal cream containing lactoferrin in the treatment of vulvovaginal candidosis]. (18487962)
2008
15
Vulvovaginal candidiasis: diagnostic and therapeutic approaches used by Dutch general practitioners. (18464170)
2008
16
Effect of antibiotics on vulvovaginal candidiasis: a MetroNet study. (18612052)
2008
17
Prevalence of vulvovaginitis and bacterial vaginosis in patients with koilocytosis. (19274321)
2008
18
Methylrosaniline chloride stained vaginal smears for the diagnosis of vulvovaginal candidiasis. (17904142)
2007
19
Sample-based assessment of the microbial etiology of bovine necrotic vulvovaginitis. (17553557)
2007
20
Risk factors for recurrent vulvovaginal candidiasis in women receiving maintenance antifungal therapy: results of a prospective cohort study. (15041994)
2004
21
"Not thrush again!" Women's experience of post-antibiotic vulvovaginitis. (12831384)
2003
22
Management of patients with recurrent vulvovaginal candidiasis. (12749733)
2003
23
Vulvovaginitis in prepubertal girls. (12651758)
2003
24
Prevention and treatment of vulvovaginal candidiasis using exogenous Lactobacillus. (12774870)
2003
25
Vulvovaginal candidiasis. (12228137)
2002
26
Pathogenesis of Recurrent Vulvovaginal Candidiasis. (12433327)
2002
27
Acute glomerulonephritis with group A streptococcal vulvovaginitis. (11156071)
2000
28
Value of Candida polymerase chain reaction and vaginal cytokine analysis for the differential diagnosis of women with recurrent vulvovaginitis. (11220486)
2000
29
Allergic vulvovaginitis. (11061467)
2000
30
Vulvovaginitis: clinical features, aetiology, and microbiology of the genital tract. (10373139)
1999
31
Group B streptococcal vulvovaginitis. (9204033)
1997
32
Clinical and cost considerations in the pharmacotherapy of vulvovaginal candidiasis. (10160477)
1996
33
Role of antifungal drug resistance in the pathogenesis of recurrent vulvovaginal candidiasis. (8912167)
1996
34
The impact of oral contraception on vulvovaginal candidiasis. (7628203)
1995
35
Treatment options for vulvovaginal candidiasis, 1993. (7795112)
1995
36
Systemic treatment of recurrent candidal vulvovaginitis by Itraconazole. (8020181)
1994
37
Vulvovaginitis in the postmenopausal woman. (1472888)
1992
38
Study of parasitological causes of vulvovaginitis in Egyptian children. (3418144)
1988
39
Papers selected from presentations given at the symposium "Vulvovaginal Candidiasis: Current Views". January 10-11, 1987. (3364510)
1988
40
Bleeding and vulvovaginitis in the pediatric age group. (3308254)
1987
41
Candida tropicalis vulvovaginitis. (3895072)
1985
42
Vulvovaginal candidiasis: treatment and recurrence. (6963163)
1982
43
Treatment of fungal vulvovaginitis with Canesten. (751276)
1978
44
Diagnosis of Candida vulvovaginitis. (342550)
1978
45
Vulvovaginal candidiasis treated with clotrimazole cream in seven days compared with fourteen-day treatment with miconazole cream. (360842)
1978
46
Comparative evaluation of Monistat and Mycostatin in the treatment of vulvovaginal candidiasis. (4604245)
1974
47
Combined radical surgery, radiation therapy and chemotherapy in infants with vulvovaginal embryonal rhabdomyosarcoma. (4742656)
1973
48
A passive haemagglutination test for the demonstration of antibody to infectious bovine rhinotracheitis-infectious pustular vulvovaginitis virus. 1. Standardisation of test components. (4798201)
1973
49
Gonococcal vulvovaginitis and possible peritonitis in prepubertal girls. (4996392)
1971
50
Diabetic vulvovaginitis treated with vitamin E suppositories. (13124418)
1954

Variations for Vulvovaginitis

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Expression for genes affiliated with Vulvovaginitis

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Expression patterns in normal tissues for genes affiliated with Vulvovaginitis

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Pathways for genes affiliated with Vulvovaginitis

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Compounds for genes affiliated with Vulvovaginitis

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Compounds related to Vulvovaginitis according to GeneCards/GeneDecks:

(show all 48)
idCompoundScoreTop Affiliating Genes
1cdcl2449.8HSPD1, HSPA4
2amp-pnp28 4410.8HSPD1, HSPA4
3sodium arsenite449.7HSPD1, HSPA4
4alpha-ketoglutarate449.7HSPA4, HSPD1
5manganese superoxide449.7HSPD1, HSPA4
6malondialdehyde449.7HSPA4, HSPD1
7neomycin449.7HSPD1, HSPA4
8latex449.7HSPA4, HSPD1
9mannitol44 1110.7HSPA4, HSPD1
10arsenite44 2410.7HSPD1, HSPA4
11polyacrylamide449.6HSPA4, HSPD1
12n acetylcysteine449.6HSPA4, HSPD1
13indomethacin44 28 61 1112.6HSPA4, HSPD1
14nmda44 2810.6HSPA4, HSPD1
15fibrinogen449.6HSPA4, HSPD1
16ketamine44 28 1111.6HSPA4, IL10
17pd 98,059449.6HSPD1, HSPA4
18ibuprofen44 28 50 24 1113.5IL10, HSPA4
1915-deoxy-delta-12,14-prostaglandin j2449.5IL10, HSPA4
204-hydroxynonenal44 2410.5IL10, HSPA4
21doxorubicin44 50 1111.5HSPA4, HSPD1
22chloroquine44 2 50 28 1113.5IL10, HSPA4
23gemcitabine44 50 1111.5HSPA4, IL10
24quercetin44 61 24 1112.5HSPA4, IL10
25p 277449.5IL10, HSPD1
26bifidobacterium449.5IL10, HSPD1
27toxin-1449.5IL10, HSPD1
28thyroxine44 2410.5HSPA4, IL10
29tuberculin449.5IL10, HSPD1
30polymyxin b449.5HSPD1, IL10
31dmso449.5IL10, HSPA4
32glutamine449.4HSPA4, HSPD1
33sb 20358044 6110.4HSPA4, IL10
34iron44 2410.4HSPA4, HSPD1
35biotin44 24 1111.4IL10, HSPD1
36endotoxin449.4IL10, HSPD1
37rantes449.3HSPD1, IL10
38ly294002449.3IL10, HSPA4
39hydrogen44 2410.3HSPD1, HSPA4
40superoxide44 2410.3HSPA4, HSPD1
41fatty acid449.2HSPA4, HSPD1
42cyclosporin a44 28 6111.2HSPD1, IL10
43lactate449.0HSPA4, HSPD1
44paraffin448.9IL10, HSPA4, HSPD1
45aspartate448.9IL10, HSPA4, HSPD1
46cycloheximide448.9IL10, HSPA4, HSPD1
47dexamethasone44 50 28 1111.9IL10, HSPA4, HSPD1
48vegf448.9HSPD1, HSPA4, IL10

GO Terms for genes affiliated with Vulvovaginitis

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Biological processes related to Vulvovaginitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chaperone-mediated protein complex assemblyGO:0511319.3HSPA4, HSPD1
2response to unfolded proteinGO:0069869.0HSPA4, HSPD1
3negative regulation of apoptotic processGO:0430669.0IL10, HSPD1
4B cell proliferationGO:0421008.9IL10, HSPD1

Products for genes affiliated with Vulvovaginitis

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Sources for Vulvovaginitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet