MCID: VLV010
MIFTS: 41

Vulvovaginitis

Categories: Reproductive diseases

Aliases & Classifications for Vulvovaginitis

MalaCards integrated aliases for Vulvovaginitis:

Name: Vulvovaginitis 12 52 42 14 69
Vulvo-Vaginitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2273
ICD10 33 N76.0
MeSH 42 D014848
NCIt 47 C35131
UMLS 69 C0042998

Summaries for Vulvovaginitis

MalaCards based summary : Vulvovaginitis, also known as vulvo-vaginitis, is related to vulvovaginal candidiasis and vulvovaginal gingival syndrome. An important gene associated with Vulvovaginitis is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), and among its related pathways/superpathways are Akt Signaling and Cytokine Signaling in Immune system. The drugs Miconazole and Fluconazole have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and neutrophil.

Wikipedia : 72 Vaginitis, also known as vaginal infection and vulvovaginitis, is an inflammation of the vagina and... more...

Related Diseases for Vulvovaginitis

Diseases related to Vulvovaginitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 189)
id Related Disease Score Top Affiliating Genes
1 vulvovaginal candidiasis 12.3
2 vulvovaginal gingival syndrome 11.9
3 vulvovaginal rhabdomyosarcoma 11.9
4 vaginitis 11.4
5 vulvar vestibulitis syndrome 11.1
6 candidiasis 10.8
7 vulvar disease 10.8
8 postmenopausal atrophic vaginitis 10.8
9 vaginal disease 10.8
10 restless legs syndrome 10.5 CCL11 HSPD1
11 mycobacterium marinum 10.4 CXCL8 HSPD1
12 psychotic disorder 10.4 CCL11 CXCL8
13 retinal vascular disease 10.4 CCL11 CXCL8
14 acute contagious conjunctivitis 10.3 CCL11 CXCL8
15 combined cellular and humoral immune defects with granulomas 10.3 HSPD1 IL10
16 extrahepatic bile duct adenocarcinoma 10.3 HSPD1 IL10
17 corneal intraepithelial neoplasm 10.3 CCL11 CXCL8
18 cornea cancer 10.3 HSPD1 IL10
19 fuchs' heterochromic uveitis 10.3 CCL11 CXCL8
20 conjunctival concretion 10.3 CCL11 CXCL8
21 basidiobolomycosis 10.2 CXCL8 IL10
22 drug rash with eosinophilia and systemic symptoms 10.2 CXCL8 IL10
23 congenital insensitivity to pain with hyperhidrosis 10.2 CXCL8 IL10
24 nonspecific interstitial pneumonia 10.2 CXCL8 IL10
25 infancy electroclinical syndrome 10.2 CXCL8 IL10
26 tarsal tunnel syndrome 10.2 CXCL8 IL10
27 urofacial syndrome 1 10.2 CXCL8 IL10
28 plantar wart 10.2 CXCL8 IL10
29 tricho onychic dysplasia 10.2 CXCL8 IL10
30 senile reticular retinal degeneration 10.2 CXCL8 IL10
31 distal monosomy 7q36 10.2 CXCL8 IL10
32 breast papillary carcinoma 10.2 CXCL8 IL10
33 palmoplantar keratosis 10.2 CXCL8 IL10
34 opportunistic bacterial infectious disease 10.2 HSPD1 IL10
35 vacterl association 10.2 CXCL8 IL10
36 atrophy of prostate 10.2 CXCL8 IL10
37 alcohol abuse 10.2 CXCL8 IL10
38 nasal cavity carcinoma in situ 10.2 CCL11 CXCL8
39 esophagus melanoma 10.1 CXCL8 IL10
40 choroiditis 10.1 CXCL8 IL10
41 extrahepatic bile duct papillary adenoma 10.1 CXCL8 IL10
42 endocervical type cervical mucinous adenocarcinoma 10.1 CXCL8 IL10
43 dentinogenesis imperfecta 10.1 CXCL8 IL10
44 entropion 10.1 CXCL8 IL10
45 burn scar 10.1 CXCL8 IL10
46 autosomal recessive type iv ehlers-danlos syndrome 10.1 CXCL8 IL10
47 bacterial vaginosis 10.1
48 pyelonephritis 10.1 CXCL8 IL10
49 churg-strauss syndrome 10.1 CXCL8 IL10
50 apple allergy 10.1 CCL11 CCL5

Graphical network of the top 20 diseases related to Vulvovaginitis:



Diseases related to Vulvovaginitis

Symptoms & Phenotypes for Vulvovaginitis

Drugs & Therapeutics for Vulvovaginitis

Drugs for Vulvovaginitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 52)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
2
Fluconazole Approved Phase 4,Phase 3,Phase 2,Phase 1 86386-73-4 3365
3
Clotrimazole Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 23593-75-1 2812
4
Dequalinium Approved Phase 4 6707-58-0
5
Terconazole Approved Phase 4 67915-31-5 441383
6
Clindamycin Approved, Vet_approved Phase 4,Phase 3 18323-44-9 29029
7
Ephedrine Approved Phase 4 299-42-3 9294
8
Pseudoephedrine Approved Phase 4 90-82-4 7028
9 Antifungal Agents Phase 4,Phase 3,Phase 2,Phase 1
10 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
11 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
12 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
13 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
14 Hormones Phase 4,Phase 3,Phase 2,Phase 1
15 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
16 Steroid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
17 Anti-Infective Agents, Local Phase 4,Phase 3
18 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 3
19 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2
20 Clindamycin palmitate Phase 4,Phase 3
21 Clindamycin phosphate Phase 4,Phase 3
22 Tetrahydrozoline Phase 4,Phase 3
23 Antibiotics, Antitubercular Phase 4
24 Antitubercular Agents Phase 4
25 Autonomic Agents Phase 4
26 Nasal Decongestants Phase 4
27 Ophthalmic Solutions Phase 4
28 Peripheral Nervous System Agents Phase 4
29 Pharmaceutical Solutions Phase 4,Phase 2
30 Respiratory System Agents Phase 4
31 Vasoconstrictor Agents Phase 4
32
Butoconazole Approved Phase 3 64872-77-1, 64872-76-0 47472
33
Amphotericin B Approved, Investigational Phase 3,Phase 2 1397-89-3 14956 5280965
34
Ketoconazole Approved, Investigational Phase 3 65277-42-1 47576 3823
35
Tetracycline Approved, Vet_approved Phase 3 60-54-8 5353990
36 Antiparasitic Agents Phase 3,Phase 2
37 Antiprotozoal Agents Phase 3,Phase 2
38 Liposomal amphotericin B Phase 3,Phase 2
39
Aluminum hydroxide Approved Phase 1, Phase 2 21645-51-2
40 Adjuvants, Immunologic Phase 1, Phase 2
41 Antacids Phase 1, Phase 2
42 Anti-Ulcer Agents Phase 1, Phase 2
43 Gastrointestinal Agents Phase 1, Phase 2
44 Vaccines Phase 1, Phase 2
45 Acidophilus Nutraceutical Phase 1,Early Phase 1
46
Iron Approved 7439-89-6 23925
47
Itraconazole Approved, Investigational 84625-61-6 55283
48
Metronidazole Approved 443-48-1 4173
49 Hydroxyitraconazole
50 Micronutrients

Interventional clinical trials:

(show all 46)

id Name Status NCT ID Phase Drugs
1 Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis Completed NCT02248506 Phase 4
2 Comparative Efficacy Study of 10 mg Dequalinium Chloride (Fluomizin) in the Treatment of Vulvovaginal Candidiasis Completed NCT02242695 Phase 4 Fluomizin vaginal tablets;Canesten vaginal tablets
3 Clotrimazole Vaginal Tablet vs Fluconazole for Severe Vulvovaginal Candidiasis Completed NCT02180828 Phase 4 Clotrimazole vaginal tablet;Fluconazole
4 Terconazole Vaginal Suppository vs Fluconazole for the Treatment of Severe Vulvovaginal Candidiasis Completed NCT02180100 Phase 4 Terconazole Vaginal Suppository;Fluconazole
5 Effect of Exercise on Spread of the Miconozole Nitrate OVULE in the Vagina Completed NCT00194324 Phase 4 Miconazole nitrate
6 Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections Recruiting NCT02860845 Phase 4 Antibiotic (Clindamycin);Antifungal (Clotrimazole)
7 Vaginal Infection Study Completed NCT00616330 Phase 3 clindamycin phosphate/butoconazole nitrate;clindamycin phosphate;butoconazole nitrate
8 Study of the Efficacy and Tolerance of Intra-vaginal Treatment With a Total Freeze-dried Culture of Lcr Regenerans® in the Prevention of Relapses of Recurrent Vulvovaginal Candidiasis Completed NCT02251093 Phase 3 Lcr Regenerans;Placebo
9 The Study Of Fluconazole For Vulvovaginal Candidiasis Completed NCT01806623 Phase 3 Fluconazole
10 Comparative Efficacy of Ovule vs Tablet Completed NCT00755053 Phase 3 Clotrimazole, vaginal ovule;Clotrimazole, vaginal tablet
11 A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077) Completed NCT01293643 Phase 3 100 mg clindamycin /800 mg ketoconazole vaginal ovule;100 mg tetracycline hydrochloride /50 mg amphotericin B cream
12 Diabetes Mellitus and Vulvovaginal Candidiasis Completed NCT00353561 Phase 3 Boric;Fluconazole
13 ProF-001_Phase IIa Recruiting NCT03115073 Phase 2, Phase 3 Candiplus;Clotrimazole
14 Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Cream. Not yet recruiting NCT03005353 Phase 2, Phase 3 Cumin seed extract;clotrimazole
15 Efficacy, Safety LactiSal 1% Gel, LactSal 50 mg, Clotrimazole 100 mg Tablet in Treatment Vulvovaginal Candidiasis Not yet recruiting NCT02907307 Phase 3 Clotrimazole vaginal tablet 100mg
16 Safety and Efficacy of Oral Encochleated Amphotericin B (CAMB/MAT2203) in the Treatment of Vulvovaginal Candidiasis (VVC) Completed NCT02971007 Phase 2 Oral Encochleated Amphotericin B (CAMB);Fluconazole
17 RADIANT: CD101 vs Standard of Care in Subjects With Acute Vaginal Yeast Infections Completed NCT02733432 Phase 2 CD101 gel (3%);CD101 gel (1%);CD101 ointment (6%);CD101 ointment (1%);Fluconazole
18 TOL-463 Phase 2 Study for Vaginitis Completed NCT02866227 Phase 2 TOL-463;TOL-463
19 Safety and Efficacy of Oral SCY-078 vs. Oral Fluconazole in Subjects With Vulvovaginal Candidiasis Completed NCT02679456 Phase 2 SCY-078;Fluconazole
20 Safety, Tolerability, Immunogenicity and Efficacy of NDV-3A Vaccine in Preventing Recurrent Vulvovaginal Candidiasis Completed NCT01926028 Phase 1, Phase 2
21 A Study to Evaluate Oral VT-1161 in the Treatment of Patients With Acute Vaginal Candidiasis (Yeast Infection) Completed NCT01891331 Phase 2 VT-1161 (oral);Fluconazole (oral)
22 MGCD290 and Fluconazole Versus Fluconazole Alone for the Treatment of Moderate to Severe Vulvovaginal Candidiasis Completed NCT01497223 Phase 2 MGCD290
23 Arasertaconazole Nitrate Pessaries - Dose Finding Study for the Vulvovaginal Candidiasis (VVC) Treatment Completed NCT01144286 Phase 2 arasertaconazole nitrate;placebo
24 An Active-Controlled, Dose-Finding Study of SCY-078 vs. Oral Fluconazole in Subjects With Acute Vulvovaginal Candidiasis Recruiting NCT03253094 Phase 2 Fluconazole;SCY-078
25 A Study to Evaluate Oral VT-1161 in the Treatment of Patients With Recurrent Vaginal Candidiasis (Yeast Infection) Active, not recruiting NCT02267382 Phase 2 VT-1161;Placebo
26 Efficacy and Safety of Oral Encochleated Amphotericin B (CAMB) in the Treatment of Fluconazole-Resistant Vulvovaginal Candidiasis Not yet recruiting NCT03167957 Phase 2 Oral Encochleated Amphotericin B (CAMB);Oral Encochleated Amphotericin B (CAMB)
27 Patients With Vulvovaginal Candidiasis Not yet recruiting NCT03024502 Phase 1, Phase 2 EPP-AF Gel 1%;EPP-AF Gel 2%;Clotrimazole
28 Efficacy Vulvovaginitis Candida Terminated NCT00199264 Phase 2 Albaconazole oral solution
29 Use of Oral Probiotics as an Adjunctive Therapy to Fluconazole in the Treatment of Yeast Vaginitis Unknown status NCT00479947 Phase 1 Probiotics (Natural product);Probiotics (L. rhamnosus GR-1 and L. reuteri RC-14)
30 Study Evaluating the Optimal Dosage for Equivalence Between Lcr Regenerans® Capsules and Tablets (Lactobacillus Rhamnosus Lcr35®) on the Vaginal Flora Colonisation Completed NCT02730494 Phase 1
31 Safety and Immunogenicity Study of a Virosomal Vaccine Against Recurrent Vulvovaginal Candida Infection Completed NCT01067131 Phase 1
32 Maternal and Perinatal Outcome in Women With History of Premature Labor in Previous Pregnancy Completed NCT01375439
33 A Randomized Study Evaluating the Therapeutic Equivalence of Two Butoconazole Nitrate Vaginal Cream, 2% Formulations Completed NCT01039584 Butoconazole Nitrate Vaginal Cream;Placebo;Gynazole 1 vaginal cream
34 Monthly Itraconazole Versus Classic Homeopathy for Treatment of Recurrent Vulvovaginal Candidiasis (RVVC) Completed NCT00895453 itraconazole;lactobacillus gasseri;classic homeopathy (carcinosin M, nux vomica, pulsatilla M, ferrum metallicum, sepia M, etc. as prescribed)
35 Safety and Equivalence of a Terconazole Vaginal Suppository (Test Product) Compared to the Reference Terconazole Vaginal Suppository in the Treatment of Vulvovaginal Candidiasis Completed NCT00803738 Terconazole Vaginal Suppository;Terazol Vaginal Suppository
36 Observational Program Neo-Penotran® Forte Completed NCT01335373 Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276)
37 Non-Interventional Extension to Investigate Recurrence of Vulvovaginal Candidiasis and Candida Colonization Completed NCT02888197
38 Comparing NAAT Testing to Standard Methods for the Diagnosis of Vaginitis Completed NCT02203942
39 Study of the Microbiota, Metabolome, and Environmental Toxins in Relation to Reproductive Health in Rwandan Women Completed NCT02150655 Early Phase 1
40 Epidemiological Study in Subjects With Vulvovaginal Candidiases Recruiting NCT03064789
41 Effect of Saccharomyces Cerevisiae on Vulvo-vaginal Candidiasis Recruiting NCT02859493
42 Study of Antibiotic-induced Vaginal Yeast Infections in Healthy Women Recruiting NCT01915251
43 Women's Improvement of Sexual Health (WISH) Demonstration Project Active, not recruiting NCT03045809
44 Use of 405nm Blue Light Emitting Diode in the Treatment of Women With Vulvovaginal Candidiasis: a Clinical Trial Not yet recruiting NCT03075046
45 Prevention of Recurrent Vulvovaginal Candidiasis With Lactibiane Candisis 5M® Terminated NCT00915629
46 Effect of Saccharomyces Cerevisiae on Improving the Effectiveness of Conventional Treatment of Vulvo-vaginal Candidiasis Terminated NCT02345096

Search NIH Clinical Center for Vulvovaginitis

Cochrane evidence based reviews: vulvovaginitis

Genetic Tests for Vulvovaginitis

Anatomical Context for Vulvovaginitis

MalaCards organs/tissues related to Vulvovaginitis:

39
Testes, Colon, Neutrophil, Skin, B Cells, Ovary, Lymph Node

Publications for Vulvovaginitis

Articles related to Vulvovaginitis:

(show top 50) (show all 773)
id Title Authors Year
1
Cyproterone acetate in the treatment of oestrogen hypersensitivity vulvovaginitis. ( 28718897 )
2017
2
Recurrent vulvovaginal candidiasis. ( 28615397 )
2017
3
Stratum corneum lipid liposome-encapsulated panomycocin: preparation, characterization, and the determination of antimycotic efficacy against Candida spp. isolated from patients with vulvovaginitis in an in vitro human vaginal epithelium tissue model. ( 28831255 )
2017
4
Molecular Identification and Antifungal Susceptibility Pattern of Non-albicans Candida Species Isolated from Vulvovaginal Candidiasis ( 28688376 )
2017
5
Contribution of TLR2 pathway in the pathogenesis of vulvovaginal candidiasis. ( 28911197 )
2017
6
Recurrent vulvovaginal candidiasis. ( 28927765 )
2017
7
Fungal Profile of Vulvovaginal Candidiasis in a Tertiary Care Hospital. ( 28511380 )
2017
8
Characterization of virulence factors of vaginal and anal isolates of Candida albicans sequentially obtained from patients with vulvovaginal candidiasis in north-east Brazil. ( 28844452 )
2017
9
Vulvovaginitis and diabetes. ( 28065975 )
2017
10
Vulvovaginal candidiasis: Etiology, symptomatology and risk factors. ( 28314677 )
2017
11
Emergence of Candida glabrata in vulvovaginal candidiasis should be attributed to selective pressure or virulence ability? ( 28730269 )
2017
12
Candida Vulvovaginitis and Vulvodynia: The Mystery Continues. ( 28836889 )
2017
13
Haemophilus influenzae vulvovaginitis associated with rhinitis caused by the same clone in a prepubertal girl. ( 28621044 )
2017
14
Automatic diagnosis of vulvovaginal candidiasis from Pap smear images. ( 28419509 )
2017
15
Recurrent Vulvovaginal Candidiasis: Could It Be Related to Cell-Mediated Immunity Defect in Response to Candida Antigen? ( 28868834 )
2017
16
Prevalence of Candida albicans, Candida dubliniensis and Candida africana in pregnant women suffering from vulvovaginal candidiasis in Argentina. ( 28385421 )
2017
17
Elevated nitric oxide in recurrent vulvovaginal candidiasis - association to clinical findings. ( 28052314 )
2017
18
Prevalence of vulvovaginal candidiasis in pregnancy at three health centers in Burkina Faso. ( 28939305 )
2017
19
Vaginal Candida spp. genomes from women with vulvovaginal candidiasis. ( 28582496 )
2017
20
Effectiveness of Ageratina pichinchensis Extract in Patients with Vulvovaginal Candidiasis. A Randomized, Double-Blind, and Controlled Pilot Study. ( 28299831 )
2017
21
Characterization and identification of microbial communities in bovine necrotic vulvovaginitis. ( 28093107 )
2017
22
Comparison of vaginal ointment of honey and clotrimazole for treatment of vulvovaginal candidiasis: A random clinical trial. ( 28760590 )
2017
23
Comparison of two long-term gestagen regimens in the management of recurrent vulvovaginal candidiasis: A pilot study. ( 28066940 )
2017
24
Candida vulvovaginitis: A store with a buttery and a show window. ( 27687503 )
2017
25
Recurrent vulvovaginal candidiasis: A review of guideline recommendations. ( 28299777 )
2017
26
Efficacy of Histatin5 in a murine model of vulvovaginal candidiasis caused by Candida albicans. ( 28645176 )
2017
27
Comparison of enzymatic activities in different Candida species isolated from women with vulvovaginitis. ( 28236530 )
2017
28
Vulvovaginitis- presentation of more common problems in pediatric and adolescent gynecology. ( 28927766 )
2017
29
Prevalence of Candida africana and Candida dubliniensis, in vulvovaginal candidiasis: First Turkish Candida africana isolates from vulvovaginal candidiasis. ( 28641919 )
2017
30
Vulvovaginitis: Find the cause to treat it. ( 28322677 )
2017
31
Biofilms Formed by Isolates from Recurrent Vulvovaginal Candidiasis Patients Are Heterogeneous and Insensitive to Fluconazole. ( 28696240 )
2017
32
Is it possible to prevent recurrent vulvovaginitis? The role of Lactobacillus plantarum I1001 (CECT7504). ( 28025698 )
2016
33
Vulvovaginal laceration as a risk factor for uterine disease in postpartum dairy cows. ( 27016827 )
2016
34
Personal Hygiene and Vulvovaginitis in Prepubertal Children. ( 26187769 )
2016
35
Is human Dectin-1 Y238X gene polymorphism related to susceptibility to recurrent vulvovaginal candidiasis? ( 28681024 )
2016
36
Recurrent desquamative vulvovaginitis in a young woman. ( 26266812 )
2016
37
Vulvovaginal gingival lichen planus: report of two cases and review of literature. ( 28042431 )
2016
38
ALS1 and ALS3 gene expression and biofilm formation in Candida albicans isolated from vulvovaginal candidiasis. ( 27376044 )
2016
39
Quercetin Assists Fluconazole to Inhibit Biofilm Formations of Fluconazole-Resistant Candida Albicans in In Vitro and In Vivo Antifungal Managements of Vulvovaginal Candidiasis. ( 27915337 )
2016
40
Streptococcus pyogenes as the cause of vulvovaginitis and balanitis in children from Nis, Serbia. ( 27638252 )
2016
41
Chronic vulvovaginal candidiasis in patients using a levonorgestrel-containing intrauterine device. ( 27957732 )
2016
42
Health-related quality of life as measured with the Short-Form 36 (SF-36) questionnaire in patients with recurrent vulvovaginal candidiasis. ( 27129474 )
2016
43
Quality of life in patients with chronic vulvovaginal candidiasis: A before and after study on the impact of oral fluconazole therapy. ( 27170259 )
2016
44
The efficacy and safety of clotrimazole vaginal tablet vs. oral fluconazole in treating severe vulvovaginal candidiasis. ( 27073145 )
2016
45
Author's reply to comment on: is it possible to prevent recurrent vulvovaginitis? The role of Lactobacillus plantarum I1001 (CECT7504). ( 27988816 )
2016
46
Syngonanthus nitens Bong. (Rhul.)-Loaded Nanostructured System for Vulvovaginal Candidiasis Treatment. ( 27556451 )
2016
47
The Effects of Ozonated Olive Oil and Clotrimazole Cream for Treatment of Vulvovaginal Candidiasis. ( 27548492 )
2016
48
Clinical Recommendation: Vulvovaginitis. ( 27969009 )
2016
49
Is it possible to prevent recurrent vulvovaginitis? The role of Lactobacillus plantarum I1001 (CECT7504). ( 27393491 )
2016
50
Clinical presentation, diagnosis and treatment of vulvovaginitis in girls: a current approach and review of the literature. ( 28083751 )
2016

Variations for Vulvovaginitis

Expression for Vulvovaginitis

Search GEO for disease gene expression data for Vulvovaginitis.

Pathways for Vulvovaginitis

Pathways related to Vulvovaginitis according to GeneCards Suite gene sharing:

(show all 18)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.02 CCL11 CCL5 CXCL8 IL10
2
Show member pathways
12.96 CCL11 CCL5 CXCL8 IL10
3
Show member pathways
12.89 CCL11 CCL5 CXCL8 IL10
4
Show member pathways
12.51 CCL5 CXCL8 IL10
5
Show member pathways
12.41 CCL11 CXCL8 HSPD1 IL10
6
Show member pathways
11.98 CCL11 CCL5 CXCL8
7 11.79 CXCL8 HSPD1 IL10
8
Show member pathways
11.59 CCL11 CCL5 CXCL8
9 11.49 CCL11 CXCL8 IL10
10 11.45 CXCL8 IL10
11 11.34 CCL11 IL10
12 11.25 CXCL8 HSPD1
13 11.18 CXCL8 IL10
14 11.15 CCL11 IL10
15 11.13 CCL11 CCL5 CXCL8
16 10.82 CCL5 CXCL8 IL10
17 10.81 CCL5 CXCL8
18 10.15 CCL11 CCL5 CXCL8 IL10

GO Terms for Vulvovaginitis

Cellular components related to Vulvovaginitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.02 CCL11 CCL5 CXCL8 HSPD1 IL10

Biological processes related to Vulvovaginitis according to GeneCards Suite gene sharing:

(show all 17)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.73 CCL11 CCL5 CXCL8 IL10
2 chemotaxis GO:0006935 9.67 CCL11 CCL5 CXCL8
3 cellular response to tumor necrosis factor GO:0071356 9.58 CCL11 CCL5 CXCL8
4 positive regulation of endothelial cell proliferation GO:0001938 9.57 CCL11 IL10
5 cellular response to interferon-gamma GO:0071346 9.56 CCL11 CCL5
6 inflammatory response GO:0006954 9.56 CCL11 CCL5 CXCL8 IL10
7 monocyte chemotaxis GO:0002548 9.55 CCL11 CCL5
8 B cell proliferation GO:0042100 9.54 HSPD1 IL10
9 cellular response to fibroblast growth factor stimulus GO:0044344 9.52 CCL5 CXCL8
10 positive regulation of macrophage activation GO:0043032 9.51 HSPD1 IL10
11 response to molecule of bacterial origin GO:0002237 9.48 CXCL8 IL10
12 negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 9.46 CCL5 CXCL8
13 neutrophil activation GO:0042119 9.37 CCL5 CXCL8
14 cellular response to interleukin-1 GO:0071347 9.33 CCL11 CCL5 CXCL8
15 eosinophil chemotaxis GO:0048245 9.32 CCL11 CCL5
16 chemokine-mediated signaling pathway GO:0070098 9.13 CCL11 CCL5 CXCL8
17 neutrophil chemotaxis GO:0030593 8.8 CCL11 CCL5 CXCL8

Molecular functions related to Vulvovaginitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.13 CCL11 CCL5 CXCL8
2 cytokine activity GO:0005125 8.92 CCL11 CCL5 CXCL8 IL10

Sources for Vulvovaginitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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