MCID: WSR001
MIFTS: 11

Was-Related Disorders malady

Categories: Genetic diseases

Aliases & Classifications for Was-Related Disorders

Aliases & Descriptions for Was-Related Disorders:

Name: Was-Related Disorders 23 24

Characteristics:

GeneReviews:

23
Penetrance Penetrance is complete in males with a was pathogenic variant...

Classifications:



Summaries for Was-Related Disorders

MalaCards based summary : Was-Related Disorders is related to thrombocytopenia, x-linked and wiskott-aldrich syndrome. An important gene associated with Was-Related Disorders is WAS (Wiskott-Aldrich Syndrome). The drugs Rocuronium and Benzocaine have been mentioned in the context of this disorder.

GeneReviews: NBK1178

Related Diseases for Was-Related Disorders

Diseases related to Was-Related Disorders via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 thrombocytopenia, x-linked 10.9
2 wiskott-aldrich syndrome 10.7

Symptoms & Phenotypes for Was-Related Disorders

Drugs & Therapeutics for Was-Related Disorders

Drugs for Was-Related Disorders (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 76)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
2
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
3
Lactulose Approved Phase 4 4618-18-2 11333
4 tannic acid Approved, Nutraceutical Phase 4
5 Analgesics Phase 4,Phase 3
6 Neuromuscular Agents Phase 4
7 Neuromuscular Blocking Agents Phase 4
8 Neuromuscular Nondepolarizing Agents Phase 4
9 Peripheral Nervous System Agents Phase 4,Phase 3
10 Vasodilator Agents Phase 4
11 Phosphodiesterase 5 Inhibitors Phase 4
12 Sildenafil Citrate Phase 4 171599-83-0
13 Gastrointestinal Agents Phase 4
14 Phosphodiesterase Inhibitors Phase 4
15 Citrate Nutraceutical Phase 4
16
Citric Acid Nutraceutical, Vet_approved Phase 4 77-92-9 311
17
Dexmedetomidine Approved, Vet_approved Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
18
Lamotrigine Approved, Investigational Phase 3 84057-84-1 3878
19
Paclitaxel Approved, Vet_approved Phase 2, Phase 3 33069-62-4 36314
20 calcium channel blockers Phase 3
21 Adrenergic Agents Phase 3
22 Adrenergic Agonists Phase 3
23 Adrenergic alpha-2 Receptor Agonists Phase 3
24 Adrenergic alpha-Agonists Phase 3
25 Neurotransmitter Agents Phase 3
26 Analgesics, Non-Narcotic Phase 3
27 Anesthetics Phase 3
28 Hypnotics and Sedatives Phase 3
29 Calcium, Dietary Phase 3
30 Central Nervous System Depressants Phase 3
31 Sodium Channel Blockers Phase 3
32 Diuretics, Potassium Sparing Phase 3
33 Excitatory Amino Acid Antagonists Phase 3
34 Excitatory Amino Acids Phase 3
35 Anticonvulsants Phase 3
36 Albumin-Bound Paclitaxel Phase 2, Phase 3
37
Gemcitabine Approved Phase 2 95058-81-4 60750
38
Gefitinib Approved, Investigational Phase 2 184475-35-2 123631
39
Docetaxel Approved May 1996, Investigational Phase 2 114977-28-5 148124 9877265
40 Anti-Infective Agents Phase 2
41 Immunosuppressive Agents Phase 2
42 Protein Kinase Inhibitors Phase 2
43 Antimetabolites Phase 2
44 Antimetabolites, Antineoplastic Phase 2
45 Antimitotic Agents Phase 2
46 Antiviral Agents Phase 2
47
Ethanol Approved 64-17-5 702
48
Midazolam Approved, Illicit 59467-70-8 4192
49
Lidocaine Approved, Vet_approved 137-58-6 3676
50
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943

Interventional clinical trials:

(show all 27)
id Name Status NCT ID Phase
1 Influence of Profound Muscle Relaxation on Muscle Trauma and Postoperative Pulmonary Function Unknown status NCT01804933 Phase 4
2 Effect of Lactulose on Minimal Hepatic Encephalopathy and Health-Related Quality of Life Completed NCT00375375 Phase 4
3 A Study to Evaluate Self-esteem and Relationships in Males With Erectile Dysfuntion Completed NCT00648596 Phase 4
4 Dexmedetomidine on Postoperative Delirium and Quality of Recovery in Geriatric Patients Unknown status NCT01283412 Phase 3
5 Lamotrigine for Symptoms of Geriatric Bipolar Depression Completed NCT00621842 Phase 3
6 An Efficacy and Safety Study to Evaluate Ranger DEB for BTK Angioplasty in Patients With CLI (RANGER-BTK) Recruiting NCT02856230 Phase 2, Phase 3
7 Randomized Phase 2 Study of 3 Therapeutic Modalities in PS 2/3 Patients With NSCLC Stage IIIB/IV Completed NCT00198393 Phase 2
8 The Effect of Blood Flow in the Maturing Arteriovenous Access for Hemodialysis on the Development of Pulmonary Hypertension. Completed NCT00739375 Phase 1
9 Development and Prevention of Pulmonary Hypertension in Systemic Sclerosis Unknown status NCT01840748
10 Immune Response to Influenza Vaccine in HIV-Infected Individuals Completed NCT00069914
11 Atherosclerosis and Omega-3 Fatty Acids in Alaskan Natives Completed NCT00005236
12 Prospective Clinical Evaluation of Periodontal Response to Different Prosthetic Margin Design Completed NCT02276586
13 Comparison of Changes of Inflammatory Proteins in Aqueous Humour of Subjects Treated With Avastin vs Lucentis Completed NCT01760746
14 Tricuspid Regurgitant Jet Velocity as an Independent Marker for Mortality in Sickle Cell Anemia Completed NCT01783093
15 Non-anesthesiologist-administered Propofol During the Flexible Bronchoscopy Completed NCT02820051
16 Effects of Diet on Reflux and Dyspepsia Completed NCT02425553
17 Obestatin Change in Distal Gastrectomy Completed NCT00822718
18 Effects of Continuous Passive Motion on the Spinal Circuitries and Its Adaptation in Patients With Spasticity Resulting From Upper Motor Neuron Lesions Completed NCT02122276
19 Exercise-induced Pulmonary Hypertension in Patients With Sickle-cell Anemia Completed NCT00948012
20 Gait Initiation Difficulty and Anticipatory Postural Adjustment (APA) Impairment in People With PD - Evaluation and Training Recruiting NCT02656355
21 Optimal Site for Rapid Urease Test in the Stomach Recruiting NCT02945137
22 A Study of Circulating Immune Cell Activity Changes in Blood of Colorectal Cancer Patients Recruiting NCT02869269
23 Polymorphisms in Key Genes of Glycolytic Pathway: Influence on Radiosensitivity in Nasopharyngeal Carcinoma Recruiting NCT02481089
24 Pulmonary Embolism and PCT. PE-PCT Study Recruiting NCT02261610
25 Long-Term Impact of Human Papillomavirus (HPV) on Quality of Life Recruiting NCT01181648
26 Effect of Intensive Low Sodium Restriction on Glomerular Infiltration Rate in Chronic Kidney Disease Enrolling by invitation NCT02519894
27 Effect of Dexmedetomidine on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery Not yet recruiting NCT02698930

Search NIH Clinical Center for Was-Related Disorders

Genetic Tests for Was-Related Disorders

Genetic tests related to Was-Related Disorders:

id Genetic test Affiliating Genes
1 Was-Related Disorders 24 WAS

Anatomical Context for Was-Related Disorders

Publications for Was-Related Disorders

Articles related to Was-Related Disorders:

id Title Authors Year
1
WAS-Related Disorders ( 20301357 )
1993

Variations for Was-Related Disorders

Expression for Was-Related Disorders

Search GEO for disease gene expression data for Was-Related Disorders.

Pathways for Was-Related Disorders

GO Terms for Was-Related Disorders

Sources for Was-Related Disorders

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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