WFS
MCID: WTR001
MIFTS: 31

Waterhouse-Friderichsen Syndrome (WFS) malady

Infectious, Endocrine categories

Summaries for Waterhouse-Friderichsen Syndrome

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A meningococcal meningitis described as an adrenal gland hypofunction disease functionally, resulting from a meningococcal infection caused by the bacterium neisseria meningitidis, which is characterized by hemorrhages in the adrenal glands, usually observed in severe cases of meningitis. infection can also be caused by streptococcus pneumoniae infection. staphylococcus aureus has recently also been implicated in pediatric wfs. the symptoms include fever, rigors, vomiting, headache, rash, hypotension and septic shock.

MalaCards: Waterhouse-Friderichsen Syndrome, also known as waterhouse-friderichsen syndrome, meningococcal, is related to diabetes insipidus and wolfram syndrome 2. An important gene associated with Waterhouse-Friderichsen Syndrome is CISD2 (CDGSH iron sulfur domain 2). Affiliated tissues include skin, lung and spleen.

Wikipedia:64 Waterhouse–Friderichsen syndrome (WFS) or hemorrhagic adrenalitis or Fulminant meningococcemia, is... more...

Aliases & Classifications for Waterhouse-Friderichsen Syndrome

Sources:
8Disease Ontology, 10DISEASES, 49Orphanet, 61UMLS, 57SNOMED-CT, 35MeSH, 40NCIt, 36MESH via Orphanet, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious
Anatomical: Endocrine


Aliases & Descriptions:

waterhouse-friderichsen syndrome 8 10 49 61
waterhouse-friderichsen syndrome, meningococcal 61
meningococcal hemorrhagic adrenalitis 8
wolfram syndrome 61
wfs 8


External Ids:

Disease Ontology8 DOID:9931
MeSH35 D014884
NCIt40 C85225
MESH via Orphanet36 D014884
ICD10 via Orphanet26 A39.1+, E35.1*
SNOMED-CT via Orphanet58 36102002
UMLS via Orphanet62 C0043068
ICD1025 A39.1

Related Diseases for Waterhouse-Friderichsen Syndrome

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Waterhouse-Friderichsen Syndrome:



Diseases related to waterhouse-friderichsen syndrome

Clinical Features for Waterhouse-Friderichsen Syndrome

Drugs & Therapeutics for Waterhouse-Friderichsen Syndrome

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Waterhouse-Friderichsen Syndrome

Anatomical Context for Waterhouse-Friderichsen Syndrome

Sources:
33MalaCards
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MalaCards organs/tissues related to Waterhouse-Friderichsen Syndrome:

33
Skin, Lung, Spleen, Adrenal gland, B cells

Animal Models for Waterhouse-Friderichsen Syndrome or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Waterhouse-Friderichsen Syndrome

Sources:
51PubMed
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Articles related to Waterhouse-Friderichsen Syndrome:

(show top 50)    (show all 115)
idTitleAuthorsYear
1
Adrenomegaly and septic adrenal hemorrhage (Waterhouse-Friderichsen syndrome) in the setting of congenital adrenal hyperplasia. (23814386)
2013
2
Waterhouse Friderichsen Syndrome Complicating Fulminant Enterobacter Cloacae Sepsis in a Preterm Infant: The Unresolved Issue of Corticosteroids. (24328998)
2013
3
Waterhouse-friderichsen syndrome in an adult patient with meningococcal meningitis. (23716842)
2013
4
Waterhouse-friderichsen syndrome in an adult patient with meningococcal meningitis. (21772601)
2011
5
Waterhouse-friderichsen syndrome caused by invasive haemophilus influenzae type B infection in a previously healthy young man. (20191807)
2010
6
Fatal pneumococcal Waterhouse-Friderichsen syndrome in a vaccinated adult with congenital asplenia. (19751638)
2009
7
Case of Waterhouse Friderichsen Syndrome during outbreak of meningococcal disease in Delhi in May 2005. (16749283)
2005
8
Spontaneous Waterhouse-Friderichsen syndrome in a gang-housed baboon. (11515675)
2001
9
Fatal pneumococcal Waterhouse-Friderichsen syndrome. (11482865)
2001
10
Waterhouse-Friderichsen syndrome secondary to Capnocytophaga canimorsus septicemia and demonstration of bacteremia by peripheral blood smear. (10835521)
2000
11
Waterhouse-Friderichsen syndrome and bilateral renal cortical necrosis in meningococcal sepsis. (10922319)
2000
12
Waterhouse-Friderichsen syndrome complicating primary biliary sepsis due to Pasteurella multocida in a patient with cirrhosis. (7560209)
1995
13
Lethal Waterhouse-Friderichsen syndrome in posttraumatic asplenia. (7473978)
1995
14
Waterhouse-Friderichsen syndrome resulting from colchicine overdose. (8258815)
1993
15
Fatal pneumococcal bacteremia with disseminated intravascular coagulation and Waterhouse-Friderichsen syndrome in a vaccinated splenectomized adult. Case report. (2368552)
1990
16
Waterhouse-Friderichsen syndrome caused by Haemophilus influenzae type b in an immunocompetent young adult. (2595428)
1989
17
Pneumococcal Waterhouse-Friderichsen syndrome despite a normal spleen. (2608604)
1989
18
Haemophilus influenzae meningitis and Waterhouse-Friderichsen syndrome in an adult. (3738579)
1986
19
Adrenal, cutaneous and myocardial lesions in fulminating endotoxinemia (Waterhouse-Friderichsen syndrome). (7134067)
1982
20
Disseminated intravascular coagulation and the Waterhouse-Friderichsen syndrome. (5118056)
1971
21
Waterhouse-Friderichsen syndrome induced by pneumococcemic shock. (5467531)
1970
22
The pathology of the Waterhouse-Friderichsen syndrome. (5504755)
1970
23
Fatal meningitis due to Moraxella duplex: report of a case with Waterhouse-Friderichsen syndrome. (5655280)
1968
24
Skin sloughs in Waterhouse-Friderichsen syndrome. Case report. (4881013)
1968
25
Skin sloughing and peripheral gangrene in a case of Waterhouse-Friderichsen syndrome, probably caused by E. coli septicaemia. (4861368)
1967
26
A case of Waterhouse-Friderichsen Syndrome. (6028344)
1967
27
Multiple coagulative defects in a patient with the Waterhouse-Friderichsen syndrome. (14490551)
1962
28
WATERHOUSE-Friderichsen syndrome. (13856902)
1959
29
Meningococcic meningitis and meningococcemia with probable Waterhouse-Friderichsen syndrome. (13514273)
1958
30
The early diagnosis of the Waterhouse-Friderichsen syndrome. (13435437)
1957
31
Congenital absence of the spleen in an adult; report of a case associated with recurrent Waterhouse-Friderichsen syndrome. (13322226)
1956
32
Waterhouse-Friderichsen syndrome (W.-F.S.) (14375664)
1955
33
Waterhouse-Friderichsen syndrome: report of a case with recovery. (14350471)
1955
34
Waterhouse-Friderichsen syndrome; a review of the literature and a report of two cases of fulminating meningococcic septicemia. (13199914)
1954
35
The Waterhouse-Friderichsen syndrome. (13050387)
1953
36
Nor-epinephrine in the treatment of acute meningococcemia with shock (Waterhouse-Friderichsen syndrome) and an evaluation of adrenocortical function. (13072798)
1953
37
Waterhouse-Friderichsen syndrome of nonmeningococcal origin in an adult woman. (13067057)
1953
38
A case of Waterhouse-Friderichsen syndrome with recovery following the use of cortisone, aqueous adrenal cortical extract and chemotherapy. (14918718)
1952
39
Waterhouse-Friderichsen syndrome treated with cortisone; report of two cases. (14928604)
1952
40
Waterhouse-Friderichsen syndrome; report of cure effected with cortisone. (14850261)
1951
41
The Waterhouse-Friderichsen syndrome in the differential diagnosis of acute abdominal crises. (14782113)
1950
42
CLINICAL-pathological conference: Waterhouse-Friderichsen syndrome. (15419978)
1950
43
Waterhouse-Friderichsen syndrome. (18125262)
1949
44
Massive gastro-intestinal hemorrhage in fulminating meningococcus meningitis (Waterhouse-Friderichsen syndrome) with recovery. (20246682)
1947
45
Experimental study of purpuric meningococcemia in relation to the Shwartzmann phenomenon; with discussion of meningococcic purpura, the Waterhouse-Friderichsen syndrome and bilateral renal cortical necrosis. (20284509)
1947
46
Waterhouse-Friderichsen syndrome complicated by acute pericarditis, with recovery. (20250341)
1947
47
Waterhouse-Friderichsen syndrome in an adult. (20265341)
1947
48
Possible Waterhouse-Friderichsen syndrome with recovery. (20997539)
1946
49
Waterhouse-Friderichsen syndrome; report of a case. (21009674)
1945
50
Fulminating Septicaemia associated with Purpura and Adrenal Haemorrhage (Waterhouse-Friderichsen Syndrome). (20783292)
1940

Genetic Variations for Waterhouse-Friderichsen Syndrome

Expression for genes affiliated with Waterhouse-Friderichsen Syndrome

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Waterhouse-Friderichsen Syndrome

Search GEO for disease gene expression data for Waterhouse-Friderichsen Syndrome.

Pathways for genes affiliated with Waterhouse-Friderichsen Syndrome

Compounds for genes affiliated with Waterhouse-Friderichsen Syndrome

GO Terms for genes affiliated with Waterhouse-Friderichsen Syndrome

Products for genes affiliated with Waterhouse-Friderichsen Syndrome

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Sources for Waterhouse-Friderichsen Syndrome

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet