WFS
MCID: WTR001
MIFTS: 35

Waterhouse-Friderichsen Syndrome (WFS) malady

Infectious diseases, Endocrine diseases categories

Summaries for Waterhouse-Friderichsen Syndrome

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A meningococcal meningitis described as an adrenal gland hypofunction disease functionally, resulting from a meningococcal infection caused by the bacterium neisseria meningitidis, which is characterized by hemorrhages in the adrenal glands, usually observed in severe cases of meningitis. infection can also be caused by streptococcus pneumoniae infection. staphylococcus aureus has recently also been implicated in pediatric wfs. the symptoms include fever, rigors, vomiting, headache, rash, hypotension and septic shock.

MalaCards: Waterhouse-Friderichsen Syndrome, also known as waterhouse-friderichsen syndrome, meningococcal, is related to diabetes mellitus and diabetes insipidus. An important gene associated with Waterhouse-Friderichsen Syndrome is CISD2 (CDGSH iron sulfur domain 2). Affiliated tissues include adrenal gland, skin and spleen.

Wikipedia:63 Waterhouse–Friderichsen syndrome (WFS) or hemorrhagic adrenalitis or Fulminant meningococcemia, is... more...

Aliases & Classifications for Waterhouse-Friderichsen Syndrome

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8Disease Ontology, 10DISEASES, 48Orphanet, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Endocrine diseases


Aliases & Descriptions:

waterhouse-friderichsen syndrome 8 10 48 60
waterhouse-friderichsen syndrome, meningococcal 60
meningococcal hemorrhagic adrenalitis 8
wolfram syndrome 60
wfs 8


External Ids:

Disease Ontology8 DOID:9931
MeSH34 D014884
NCIt39 C85225
MESH via Orphanet35 D014884
ICD10 via Orphanet26 A39.1+, E35.1*
SNOMED-CT via Orphanet57 36102002
UMLS via Orphanet61 C0043068
ICD1025 A39.1

Related Diseases for Waterhouse-Friderichsen Syndrome

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Waterhouse-Friderichsen Syndrome:



Diseases related to waterhouse-friderichsen syndrome

Clinical Features for Waterhouse-Friderichsen Syndrome

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Drugs & Therapeutics for Waterhouse-Friderichsen Syndrome

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Waterhouse-Friderichsen Syndrome

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Anatomical Context for Waterhouse-Friderichsen Syndrome

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Sources:
32MalaCards
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MalaCards organs/tissues related to Waterhouse-Friderichsen Syndrome:

32
Adrenal gland, Skin, Spleen, Lung

Animal Models for Waterhouse-Friderichsen Syndrome or affiliated genes

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Publications for Waterhouse-Friderichsen Syndrome

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50PubMed
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Articles related to Waterhouse-Friderichsen Syndrome:

(show top 50)    (show all 114)
idTitleAuthorsYear
1
Adrenomegaly and septic adrenal hemorrhage (Waterhouse-Friderichsen syndrome) in the setting of congenital adrenal hyperplasia. (23814386)
2013
2
Waterhouse-friderichsen syndrome in an adult patient with meningococcal meningitis. (23716842)
2013
3
A fatal case of streptococcal and meningococcal meningitis in a 2-years-old child occurring as Waterhouse-Friderichsen Syndrome. (23910860)
2013
4
Waterhouse-friderichsen syndrome in an adult patient with meningococcal meningitis. (21772601)
2011
5
Waterhouse-friderichsen syndrome caused by invasive haemophilus influenzae type B infection in a previously healthy young man. (20191807)
2010
6
Fatal pneumococcal Waterhouse-Friderichsen syndrome in a vaccinated adult with congenital asplenia. (19751638)
2009
7
Medical image. Meningococcal septic shock with adrenal apoplexy--Waterhouse-Friderichsen syndrome. (16868589)
2006
8
Case of Waterhouse Friderichsen Syndrome during outbreak of meningococcal disease in Delhi in May 2005. (16749283)
2005
9
Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children. (16177250)
2005
10
Fatal Waterhouse-Friderichsen syndrome due to Ewingella americana infection. (12604997)
2003
11
Postmortem measurement of serum procalcitonin concentration in Waterhouse-Friderichsen syndrome. (12587602)
2002
12
Images in clinical medicine. Waterhouse-Friderichsen syndrome. (11333994)
2001
13
Lethal Waterhouse-Friderichsen syndrome in posttraumatic asplenia. (7473978)
1995
14
Waterhouse-Friderichsen syndrome resulting from colchicine overdose. (8258815)
1993
15
Fatal childhood pneumococcal Waterhouse-Friderichsen syndrome. (8451106)
1993
16
Waterhouse-Friderichsen syndrome caused by a DF-2 bacterium in a splenectomised patient. (7229096)
1981
17
Waterhouse-Friderichsen syndrome caused by Haemophilus influenzae type b in an adult. (6977494)
1981
18
Fatal cholera-like diarrhea with Waterhouse-Friderichsen syndrome, sickle-cell trait, and hyposplenism. (335288)
1977
19
Waterhouse Friderichsen syndrome. (1207489)
1975
20
Disseminated intravascular coagulation and the Waterhouse-Friderichsen syndrome. (5118056)
1971
21
The pathology of the Waterhouse-Friderichsen syndrome. (5504755)
1970
22
Fatal meningitis due to Moraxella duplex: report of a case with Waterhouse-Friderichsen syndrome. (5655280)
1968
23
Multiple coagulative defects in a patient with the Waterhouse-Friderichsen syndrome. (14490551)
1962
24
Repair after gangrene due to Waterhouse-Friderichsen syndrome. (14479206)
1962
25
Necrotizing renal papillitis review and report of a case treated by nephrectomy and complicated by Waterhouse-Friderichsen syndrome. (13512121)
1958
26
Meningococcic meningitis and meningococcemia with probable Waterhouse-Friderichsen syndrome. (13514273)
1958
27
THE WATERHOUSE-FRIDERICHSEN syndrome failure of hydrocortisone therapy. (13398680)
1957
28
The early diagnosis of the Waterhouse-Friderichsen syndrome. (13435437)
1957
29
Recovery from Waterhouse-Friderichsen syndrome associated with use of norepinephrine to combat shock. (13385639)
1957
30
Congenital absence of the spleen in an adult; report of a case associated with recurrent Waterhouse-Friderichsen syndrome. (13322226)
1956
31
Waterhouse-Friderichsen syndrome: report of a case with recovery. (14350471)
1955
32
Acute adrenal insufficiency (Waterhouse-Friderichsen syndrome) treated with cortisone. (14352101)
1955
33
Waterhouse-Friderichsen syndrome; a review of the literature and a report of two cases of fulminating meningococcic septicemia. (13199914)
1954
34
Norepinephrine in the treatment of the Waterhouse-Friderichsen syndrome; report of a case. (13098452)
1953
35
Waterhouse Friderichsen syndrome. (13071144)
1953
36
Nor-epinephrine in the treatment of acute meningococcemia with shock (Waterhouse-Friderichsen syndrome) and an evaluation of adrenocortical function. (13072798)
1953
37
Waterhouse-Friderichsen syndrome of nonmeningococcal origin in an adult woman. (13067057)
1953
38
A case of Waterhouse-Friderichsen syndrome with recovery following the use of cortisone, aqueous adrenal cortical extract and chemotherapy. (14918718)
1952
39
Waterhouse-Friderichsen syndrome treated with cortisone; report of two cases. (14928604)
1952
40
Waterhouse-Friderichsen syndrome; report of cure effected with cortisone. (14850261)
1951
41
A case of Waterhouse-Friderichsen syndrome due to hemophilus influenzae. (14880706)
1951
42
The Waterhouse-Friderichsen syndrome in the differential diagnosis of acute abdominal crises. (14782113)
1950
43
CLINICAL-pathological conference: Waterhouse-Friderichsen syndrome. (15419978)
1950
44
Waterhouse-Friderichsen syndrome. (18125262)
1949
45
Waterhouse-Friderichsen syndrome complicated by acute pericarditis, with recovery. (20250341)
1947
46
Bilateral acute hemorrhagic necrosis of the adrenals (Waterhouse-Friderichsen syndrome) in a young child. (20245933)
1946
47
Possible Waterhouse-Friderichsen syndrome with recovery. (20997539)
1946
48
Two cases of Waterhouse-Friderichsen syndrome in the same family, one with recovery under penicillin therapy. (20997708)
1946
49
Waterhouse-Friderichsen syndrome; report of case with recovery. (21004158)
1945
50
Fulminating Septicaemia associated with Purpura and Adrenal Haemorrhage (Waterhouse-Friderichsen Syndrome). (20783292)
1940

Genetic Variations for Waterhouse-Friderichsen Syndrome

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Expression for genes affiliated with Waterhouse-Friderichsen Syndrome

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Waterhouse-Friderichsen Syndrome

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Pathways for genes affiliated with Waterhouse-Friderichsen Syndrome

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Compounds for genes affiliated with Waterhouse-Friderichsen Syndrome

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GO Terms for genes affiliated with Waterhouse-Friderichsen Syndrome

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Products for genes affiliated with Waterhouse-Friderichsen Syndrome

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Sources for Waterhouse-Friderichsen Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet