WFS
MCID: WTR001
MIFTS: 35

Waterhouse-Friderichsen Syndrome (WFS) malady

Infectious diseases, Endocrine diseases categories

Summaries for Waterhouse-Friderichsen Syndrome

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A meningococcal meningitis described as an adrenal gland hypofunction disease functionally, resulting from a meningococcal infection caused by the bacterium neisseria meningitidis, which is characterized by hemorrhages in the adrenal glands, usually observed in severe cases of meningitis. infection can also be caused by streptococcus pneumoniae infection. staphylococcus aureus has recently also been implicated in pediatric wfs. the symptoms include fever, rigors, vomiting, headache, rash, hypotension and septic shock.

MalaCards: Waterhouse-Friderichsen Syndrome, also known as waterhouse-friderichsen syndrome, meningococcal, is related to diabetes mellitus and diabetes insipidus. An important gene associated with Waterhouse-Friderichsen Syndrome is CISD2 (CDGSH iron sulfur domain 2). Affiliated tissues include adrenal gland, spleen and skin.

Wikipedia:63 Waterhouse–Friderichsen syndrome (WFS) or hemorrhagic adrenalitis or Fulminant meningococcemia, is... more...

Aliases & Classifications for Waterhouse-Friderichsen Syndrome

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8Disease Ontology, 10DISEASES, 48Orphanet, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Endocrine diseases


Aliases & Descriptions:

waterhouse-friderichsen syndrome 8 10 48 60
waterhouse-friderichsen syndrome, meningococcal 60
meningococcal hemorrhagic adrenalitis 8
wolfram syndrome 60
wfs 8


External Ids:

Disease Ontology8 DOID:9931
MeSH34 D014884
NCIt39 C85225
MESH via Orphanet35 D014884
ICD10 via Orphanet26 A39.1+, E35.1*
SNOMED-CT via Orphanet57 36102002
UMLS via Orphanet61 C0043068
ICD1025 A39.1

Related Diseases for Waterhouse-Friderichsen Syndrome

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Waterhouse-Friderichsen Syndrome:



Diseases related to waterhouse-friderichsen syndrome

Clinical Features for Waterhouse-Friderichsen Syndrome

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Drugs & Therapeutics for Waterhouse-Friderichsen Syndrome

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Waterhouse-Friderichsen Syndrome

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Anatomical Context for Waterhouse-Friderichsen Syndrome

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Sources:
32MalaCards
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MalaCards organs/tissues related to Waterhouse-Friderichsen Syndrome:

32
Adrenal gland, Spleen, Skin, Lung

Animal Models for Waterhouse-Friderichsen Syndrome or affiliated genes

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Publications for Waterhouse-Friderichsen Syndrome

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50PubMed
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Articles related to Waterhouse-Friderichsen Syndrome:

(show top 50)    (show all 114)
idTitleAuthorsYear
1
The significance of adrenal hemorrhage: undiagnosed Waterhouse-Friderichsen syndrome, a case series. (23458363)
2013
2
A fatal case of streptococcal and meningococcal meningitis in a 2-years-old child occurring as Waterhouse-Friderichsen Syndrome. (23910860)
2013
3
Medical image. Meningococcal septic shock with adrenal apoplexy--Waterhouse-Friderichsen syndrome. (16868589)
2006
4
Waterhouse-Friderichsen syndrome as a result of non-meningococcal infection. (14747454)
2004
5
Postmortem measurement of serum procalcitonin concentration in Waterhouse-Friderichsen syndrome. (12587602)
2002
6
Waterhouse-Friderichsen syndrome after infection with group A streptococcus. (11702906)
2001
7
Waterhouse-Friderichsen syndrome. (11556316)
2001
8
Images in clinical medicine. Waterhouse-Friderichsen syndrome. (11333994)
2001
9
Reminder--necrotizing fasciitis complicated by Waterhouse-Friderichsen syndrome. (10454031)
1999
10
Fatal childhood pneumococcal Waterhouse-Friderichsen syndrome. (8451106)
1993
11
Group A beta-hemolytic Streptococcus and Waterhouse-Friderichsen syndrome. (1528655)
1992
12
Waterhouse-Friderichsen syndrome without purpura due to Haemophilus influenzae group B. (3873065)
1985
13
Waterhouse-Friderichsen syndrome caused by a DF-2 bacterium in a splenectomised patient. (7229096)
1981
14
Chest infection associated with the Waterhouse-Friderichsen syndrome. (6790062)
1981
15
Waterhouse-Friderichsen syndrome caused by Haemophilus influenzae type b. (316349)
1979
16
Adrenal lesions in calves dying from endotoxin shock, with special reference to the Waterhouse-Friderichsen syndrome. (858809)
1977
17
Sudden death due to Waterhouse-Friderichsen syndrome and purulent leptomeningitis caused by Acinetobacter calcoaceticus (Mima polymorpha). (883428)
1977
18
Animal model of human disease. Waterhouse-Friderichsen syndrome. Animal model: Acrylonitrile-induced adrenal apoplexy. (1258981)
1976
19
Waterhouse Friderichsen syndrome. Endotoxin shock treated with massive doses of cortisol. (4705280)
1973
20
The Waterhouse-Friderichsen syndrome and its orthopaedic consequences. (5081691)
1972
21
Fulminating meningitis with Waterhouse-Friderichsen syndrome due to Neisseria gonorrhoeae. (4989197)
1970
22
ENDOTOXEMIA AND ADRENAL HEMORRHAGE. A MECHANISM FOR THE WATERHOUSE-FRIDERICHSEN SYNDROME. (14264270)
1965
23
WATERHOUSE-FRIDERICHSEN SYNDROME. (14284854)
1965
24
Waterhouse-Friderichsen syndrome in varicella. (13772211)
1960
25
Fulminating meningococcemia (Waterhouse-Friderichsen syndrome): report of two patients successfully treated with chemotherapy, vasopressors, and adrenal steroids. (13664537)
1959
26
Fulminating meningococcemia and meningitis with vascular collapse; report of a case of Waterhouse-Friderichsen syndrome with recovery. (14397040)
1955
27
Meningococcal infections; with particular reference to fulminating meningococcemia (Waterhouse-Friderichsen syndrome) treated with cortisone and norepinephrine. (13202023)
1954
28
Mima polymorpha as a causative agent in Waterhouse-Friderichsen syndrome. (13157230)
1954
29
Waterhouse-Friderichsen syndrome. (13163651)
1954
30
The treatment of Waterhouse-Friderichsen syndrome; brief review of the literature and report of one case. (13195875)
1954
31
Norepinephrine in the treatment of the Waterhouse-Friderichsen syndrome; report of a case. (13098452)
1953
32
A fatal case of Still's disease associated with Waterhouse-Friderichsen syndrome due to pneumococcal septicaemia. (13036557)
1953
33
The prolonged Waterhouse-Friderichsen syndrome with renal and myocardial insufficiency. (13031407)
1953
34
Lung: osseous emboli after spinal tap in a case of Waterhouse-Friderichsen syndrome complicating preeclamptic toxemia. (13094139)
1953
35
Waterhouse Friderichsen syndrome. (13071144)
1953
36
Meningococcus meningitis with massive hemorrhage of the adrenals' (Waterhouse-Friderichsen syndrome) complicating pregnancy with pre-eclamptic toxemia. (13016690)
1953
37
Waterhouse-Friderichsen syndrome; report of a case with recovery. (14947936)
1952
38
Waterhouse-Friderichsen syndrome associated with septic abortion and sickle cell disease. (13002737)
1952
39
Nature of Waterhouse-Friderichsen syndrome; report of case with successful treatment with cortisone. (14850251)
1951
40
Waterhouse-Friderichsen syndrome (?) with recovery. (14825073)
1951
41
The Waterhouse-Friderichsen syndrome; report of a case. (15434890)
1950
42
Fulminating meningococcic infections and the so-called Waterhouse-Friderichsen syndrome. (18874411)
1948
43
The Waterhouse-Friderichsen syndrome in urology. (20266249)
1947
44
Waterhouse-Friderichsen syndrome; recovery from shock in fatal case. (20292900)
1947
45
A case of fulminating meningococcemia exhibiting the Waterhouse-Friderichsen syndrome and demonstrating the value of cortical extract administration. (20286912)
1947
46
Bilateral acute hemorrhagic necrosis of the adrenals in a young child (a case of Waterhouse-Friderichsen syndrome). (21066827)
1946
47
Waterhouse-Friderichsen syndrome. (20997496)
1946
48
Fulminating meningococcemia with vascular collapse (Waterhouse-Friderichsen syndrome); report on four adult patients who recovered. (21018881)
1946
49
The Waterhouse-Friderichsen Syndrome: Report of Three Cases in Adults with Necropsy Findings. (21434244)
1945
50
ADRENAL HAEMORRHAGE (WATERHOUSE-FRIDERICHSEN SYNDROME) IN A YOUNG CHILD. (20320885)
1938

Genetic Variations for Waterhouse-Friderichsen Syndrome

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Expression for genes affiliated with Waterhouse-Friderichsen Syndrome

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Waterhouse-Friderichsen Syndrome

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Pathways for genes affiliated with Waterhouse-Friderichsen Syndrome

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Compounds for genes affiliated with Waterhouse-Friderichsen Syndrome

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GO Terms for genes affiliated with Waterhouse-Friderichsen Syndrome

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Products for genes affiliated with Waterhouse-Friderichsen Syndrome

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Sources for Waterhouse-Friderichsen Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet