MCID: WLL006
MIFTS: 63

Wells Syndrome malady

Rare diseases, Skin diseases categories
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Summaries for Wells Syndrome

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NIH Rare Diseases:42 Wells syndrome is a rare eosinophilic disorder characterized by itchy, burning, red, and inflamed areas on the skin often on the lower arm or leg. the lesions may be single or multiple. they are usually red at first (looking like cellulitis) then change to brown red, to blue gray, then greenish gray. the lesions are usually painful and are sometimes associated with a fever. they typically heal without scarring within weeks to months; however they often recur. the cause of wells syndrome is unknown; but some researchers think that wells syndrome is an autoimmune reaction. last updated: 12/14/2011

MalaCards based summary: Wells Syndrome, also known as eosinophilic cellulitis, is related to muckle-wells syndrome and ankyloblepharon-ectodermal defects-cleft lip/palate syndrome, and has symptoms including cellulitis/panniculitis/pseudocellulitis/inflammation of subcutaneous tissue, cutaneous rash and pruritus/itching. An important gene associated with Wells Syndrome is NLRP3 (NLR family, pyrin domain containing 3), and among its related pathways are TRAF Pathway and Monoamine Transport. The compounds as 101 and tlck have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and colon, and related mouse phenotypes are digestive/alimentary and liver/biliary system.

CDC:3 Meet Terrie

Wikipedia:65 Eosinophilic cellulitus (also known as \"Wells\' syndrome\" from George Crichton Wells who first... more...

Aliases & Classifications for Wells Syndrome

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Sources:
42NIH Rare Diseases, 48Orphanet, 62UMLS, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet, 25ICD10
See all sources

Wells Syndrome, Aliases & Descriptions:

Name: Wells Syndrome 42 48 62
Eosinophilic Cellulitis 42 48 62
 
Bullous Cellulitis with Eosinophilia 42 62
Wells' Syndrome 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases
Orphanet: 48 
Rare skin diseases


Characteristics (Orphanet epidemiological data):

48
eosinophilic cellulitis:
Inheritance: Sporadic; Prevalence: <1/1000000; Age of onset: Adulthood; Age of death: Normal


External Ids:

MESH via Orphanet35 C536693
ICD10 via Orphanet26 L98.3
UMLS via Orphanet63 C0343101
ICD1025 L98.3

Related Diseases for Wells Syndrome

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Diseases related to Wells Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 147)
idRelated DiseaseScoreTop Affiliating Genes
1muckle-wells syndrome31.0IL1R1, MEFV, TNFRSF1A, IL1RAPL2, IL1B, CASP1
2ankyloblepharon-ectodermal defects-cleft lip/palate syndrome30.8TP63, FGFR2
3ectodermal dysplasia30.8TNFRSF1A, TP63
4urticaria30.6CASP1, IL1RAPL2, NLRP3
5amyloidosis30.5MEFV, TNFRSF1A, CRP, IL1RAPL2
6amyloidosis, secondary30.3MEFV, CRP
7vasculitis30.1MEFV, IL1RAPL2, CRP
8familial cold autoinflammatory syndrome30.0NLRP3, CASP1, IL1B, IL1R1, MEFV, TNFRSF1A
9arthropathy30.0CRP, IL1RAPL2, IL1B, NLRP3
10systemic lupus erythematosus30.0TNFRSF1A, IL1R1, IL1RAPL2, CRP
11colitis29.9IL8, IL1B, IL1RAPL2, IL1R1
12multiple sclerosis29.9CASP1, IL1B, IL1RAPL2, TNFRSF1A, IL1R1
13herpes simplex29.7CASP1, IL1RAPL2, FGFR2
14adenocarcinoma29.6CASP1, FGFR2, GNB2L1, TP63, IL1RAPL2
15ulcerative colitis29.5IL1R1, IL1RAPL2, IL1B, CRP, IL8, CASP1
16cellulitis10.6
17palindromic rheumatism10.6MEFV
18schnitzler syndrome10.6IL1R1
19polyarteritis nodosa10.6MEFV
20pericarditis10.6MEFV
21adult-onset still's disease10.5CRP
22leukemoid reaction10.5IL3
23felty's syndrome10.5IL3
24septic arthritis10.5CRP
25pyoderma gangrenosum10.5NLRP3, MEFV
26aseptic meningitis10.4IL1R1, NLRP3
27common cold10.4IL8
28bronchitis10.4CRP
29periodic fever, familial, autosomal dominant10.4MEFV, TNFRSF1A
30bacteriuria10.4CRP
31relapsing fever10.4MEFV, TNFRSF1A
32conjunctivitis10.4NLRP3, TNFRSF1A
33pleurisy10.4IL1B, MEFV
34familial mediterranean fever10.4TNFRSF1A, NLRP3, MEFV
35blau syndrome10.4IL1B, NLRP3, MEFV
36cowpox10.4TNFRSF1A, CASP1
37exanthem10.4NLRP3, CRP
38bronchiolitis10.3IL8
39gout10.3IL1B, NLRP3
40polymyalgia rheumatica10.3IL1RAPL2, CRP
41spondylarthropathy10.3CRP, IL1RAPL2
42shigellosis10.3IL1R1, CASP1, IL1B
43churg-strauss syndrome10.3
44slow-channel congenital myasthenic syndrome10.3CRP, IL8
45cerebral malaria10.3IL1R1, IL1RAPL2, IL1B
46chronic obstructive pulmonary disease10.3IL1B, CRP
47viral meningitis10.3CRP, IL8
48extrinsic allergic alveolitis10.3TNFRSF1A, IL8
49rheumatic disease10.3IL1R1, MEFV, CRP
50gastritis10.3IL8, IL1RAPL2

Graphical network of the top 20 diseases related to Wells Syndrome:



Diseases related to wells syndrome

Symptoms for Wells Syndrome

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Symptoms:

48 (show all 10)
  • cellulitis/panniculitis/pseudocellulitis/inflammation of subcutaneous tissue
  • cutaneous rash
  • pruritus/itching
  • cutaneous edema
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • eosinophils anomalies/hypereosinophilia
  • urticaria
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • follicular/erythematous/edematous papules/milium
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment

HPO human phenotypes related to Wells Syndrome:

(show all 7)
id Description Frequency HPO Source Accession
1 edema hallmark (90%) HP:0000969
2 skin rash hallmark (90%) HP:0000988
3 pruritus hallmark (90%) HP:0000989
4 abnormality of eosinophils hallmark (90%) HP:0001879
5 cellulitis hallmark (90%) HP:0100658
6 urticaria typical (50%) HP:0001025
7 abnormal blistering of the skin typical (50%) HP:0008066

Drugs & Therapeutics for Wells Syndrome

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Drug clinical trials:

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Genetic Tests for Wells Syndrome

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Anatomical Context for Wells Syndrome

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MalaCards organs/tissues related to Wells Syndrome:

32
Skin, Brain, Colon, Kidney, Thyroid, Salivary gland, Myeloid, Monocytes, T cells, B cells, Neutrophil

Animal Models for Wells Syndrome or affiliated genes

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Publications for Wells Syndrome

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Articles related to Wells Syndrome:

(show top 50)    (show all 185)
idTitleAuthorsYear
1
Renal involvement in secondary amyloidosis of Muckle-Wells syndrome: marked improvement of renal function and reduction of proteinuria after therapy with human anti-interleukin-1I^ monoclonal antibody canakinumab. (24510061)
2014
2
Muckle wells syndrome associated with multifocal clinically isolated syndrome. (24618190)
2014
3
Life of Lesions in Eosinophilic Cellulitis (Wells' Syndrome)-A Condition That May Be Missed at First Sight. (25238447)
2014
4
Eosinophilic cellulitis (Wells syndrome) in a pediatric patient: a case report and review of the literature. (22611749)
2012
5
Muckle-Wells syndrome and male hypofertility: a case series. (22512814)
2012
6
Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome. (21360513)
2011
7
NLRP3 E311K mutation in a large family with Muckle-Wells syndrome--description of a heterogeneous phenotype and response to treatment. (22146561)
2011
8
Hay-Wells syndrome of ectodermal dysplasia: A rare autosomal dominant disorder. (22346004)
2011
9
A patient with Wells' syndrome. (20500167)
2010
10
Improvement of sensoneurinal hearing loss in a patient with Muckle-Wells syndrome treated with anakinra]. (20135584)
2010
11
High responses of peripheral lymphocytes to mosquito salivary gland extracts in patients with Wells syndrome. (20542179)
2010
12
A case report of Wells' syndrome in a celiac patient. (20872333)
2010
13
Wells Syndrome with Multiorgan Involvement Mimicking Hypereosinophilic Syndrome. (20652113)
2009
14
Craniofacial and anthropometric phenotype in ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (Hay-Wells syndrome) in a cohort of 17 patients. (19676059)
2009
15
Quiz page. Muckle Wells syndrome. (18971008)
2008
16
Eosinophilic cellulitis (Wells' syndrome) in association with angioimmunoblastic lymphadenopathy. (17989892)
2007
17
Hay-wells syndrome of ectodermal dysplasia. (16444073)
2006
18
Wells syndrome: an enigmatic and therapeutically challenging disease. (17039661)
2006
19
Recovery from deafness in a patient with Muckle-Wells syndrome treated with anakinra. (16646042)
2006
20
A probable case of Muckle-Wells syndrome. (16556280)
2006
21
Rapp-Hodgkin ectodermal dysplasia syndrome: the clinical and molecular overlap with Hay-Wells syndrome. (16532463)
2006
22
Successful treatment of acute visual loss in Muckle-Wells syndrome with interleukin 1 receptor antagonist. (16014694)
2005
23
Bullous &quot;cellulitis&quot; with eosinophilia: case report and review of Wells' syndrome in childhood. (15995016)
2005
24
TNFRSF1A-associated periodic syndrome (TRAPS), Muckle-Wells syndrome (MWS) and renal amyloidosis. (12832748)
2003
25
Wells' syndrome: a clinical and histopathologic review of seven cases. (12581147)
2003
26
Herpes simplex virus type 2-associated eosinophilic cellulitis (Wells' syndrome). (12734477)
2003
27
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. (12815153)
2003
28
Wells syndrome. (14533832)
2003
29
New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes. (11992256)
2002
30
Nodular presentation of eosinophilic cellulitis (Wells' syndrome). (11722455)
2001
31
Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63. (11159940)
2001
32
Wells' syndrome (eosinophilic cellulitis): correlation between clinical activity, eosinophil levels, eosinophil cation protein and interleukin-5. (10215782)
1999
33
Genetic linkage of the Muckle-Wells syndrome to chromosome 1q44. (10486324)
1999
34
Circadian elevation of IL-6 levels in Muckle-Wells syndrome: a disorder of the neuro-immune axis? (9797932)
1998
35
Wells' syndrome associated with idiopathic hypereosinophilic syndrome. (9470919)
1997
36
Wells' syndrome responsive to PUVA therapy. (9349363)
1997
37
Toxocariasis and Wells' syndrome: a causal relationship? (9529550)
1997
38
Congenital Wells syndrome. (9263317)
1997
39
Recurrent urticarial skin eruption since infancy. Muckle-Wells syndrome (MWS). (7826101)
1995
40
The arthropathy of the Muckle-Wells syndrome. (8000753)
1994
41
Iritis and Wells' syndrome. (1459774)
1992
42
Wells' syndrome in children: varicella infection as a precipitating event. (2004004)
1991
43
Amyloid goiter and arthritides after kidney transplantation in a patient with systemic amyloidosis and Muckle-Wells syndrome. (2589249)
1989
44
Eosinophilic infiltration with flame figures. A distinctive tissue reaction seen in Wells' syndrome and other diseases. (3728877)
1986
45
Eosinophilic cellulitis (Wells' syndrome) (4015127)
1985
46
Recurrent granulomatous dermatitis with eosinophilia. Wells' syndrome. (6724778)
1984
47
Wells' syndrome: is there collagen damage in the flame figures? (6520258)
1984
48
Identification of amyloid A protein in a sporadic Muckle-Wells syndrome. N-terminal amino acid sequence after isolation from formalin-fixed tissue. (6406764)
1983
49
The Muckle-Wells syndrome and the major histocompatibility complex. (6857626)
1983
50
Wells' syndrome. Recurrent granulomatous dermatitis with eosinophilia. (443839)
1979

Variations for Wells Syndrome

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Expression for genes affiliated with Wells Syndrome

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Expression patterns in normal tissues for genes affiliated with Wells Syndrome

Search GEO for disease gene expression data for Wells Syndrome.

Pathways for genes affiliated with Wells Syndrome

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Pathways related to Wells Syndrome according to GeneCards/GeneDecks:

(show all 37)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9CASP1, TNFRSF1A
2
Show member pathways
Serotonin Transporter Activity37
9.9IL1B, IL1R1
39.9CASP1, IL1B
4
Show member pathways
IL-1 Signaling Pathway37
IL1-mediated signaling events37
9.7IL1R1, IL1B, CASP1
59.6TNFRSF1A, IL1R1, IL1B
6
Show member pathways
9.6TNFRSF1A, IL1R1, IL1B
79.6TNFRSF1A, IL3, IL1R1
89.6IL1B, IL1R1, IL3
9
Show member pathways
9.5IL1B, IL3, TNFRSF1A
109.5IL8, GNB2L1
119.5IL1B, IL8, IL1R1
12
Show member pathways
Immune response MIF in innate immunity response60
9.5IL1B, IL8, IL1R1
139.5IL1R1, IL8, IL1B
149.5CASP1, IL1B, IL8
15
Show member pathways
9.5CASP1, IL1B, IL8
16
Show member pathways
9.5IL1R1, IL1B, FGFR2
179.4IL1B, IL8, IL3
189.4IL1B, IL8, IL3
19
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
9.4TNFRSF1A, TP63, IL1R1, CASP1
20
Show member pathways
9.3CASP1, IL1B, IL1R1, IL3
21
Show member pathways
9.3IL3, IL1R1, IL1B, CASP1
229.3NLRP3, CASP1, IL1B, IL8
239.2IL1B, IL8, IL1R1, TNFRSF1A
24
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.2TNFRSF1A, IL1R1, IL8, IL1B
25
Show member pathways
9.2TNFRSF1A, IL1R1, IL1B, FGFR2
26
Show member pathways
9.0NLRP3, CASP1, IL1B, IL8, MEFV
27
Show member pathways
9.0TNFRSF1A, IL3, IL1R1, IL1B, CASP1
28
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
9.0IL1R1, IL8, IL1B, CASP1, NLRP3
29
Show member pathways
MAPK signaling pathway37
8.9TNFRSF1A, IL1R1, IL1B, CASP1, FGFR2
30
Show member pathways
8.8TNFRSF1A, IL3, IL1R1, IL1B, FGFR2
31
Show member pathways
8.8TNFRSF1A, IL3, IL1B, CASP1, FGFR2
32
Show member pathways
8.5GNB2L1, TNFRSF1A, IL8, IL1B, CASP1, NLRP3
33
Show member pathways
8.4TNFRSF1A, IL3, IL1R1, IL8, IL1B, FGFR2
34
Show member pathways
8.4TNFRSF1A, IL3, IL1R1, IL8, IL1B, FGFR2
35
Show member pathways
8.2TNFRSF1A, IL3, IL1R1, IL8, IL1B, CASP1
36
Show member pathways
8.2TNFRSF1A, IL3, IL1R1, IL8, IL1B, CASP1
37
Show member pathways
7.9GNB2L1, TNFRSF1A, IL3, IL1R1, IL8, IL1B

Compounds for genes affiliated with Wells Syndrome

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Compounds related to Wells Syndrome according to GeneCards/GeneDecks:

(show top 50)    (show all 151)
idCompoundScoreTop Affiliating Genes
1as 10144 6110.7IL1B, CASP1, IL1R1, IL3
2tlck449.7IL8, IL1B, CASP1
3mevalonate449.7TNFRSF1A, MEFV, CASP1, NLRP3
4p005449.6IL1R1, CRP, TP63, TNFRSF1A
5tenidap44 2810.5IL1B, IL1R1, CRP
6diphenyleneiodonium449.5CASP1, IL1B, IL8, IL1R1
7peptidoglycan44 2810.5CASP1, IL1B, IL8, IL1R1
8poly(i-c)449.5IL8, CASP1, IL1B, IL3
9leflunomide44 50 1111.5IL1B, IL1RAPL2, IL1R1, TNFRSF1A
10adalimumab44 50 1111.4IL1RAPL2, TNFRSF1A, IL1R1, CRP
11monosodium urate449.4IL1B, IL8, IL1R1, IL1RAPL2
12polysulfone449.4IL1B, IL1RAPL2, IL1R1, CRP
13muramyl dipeptide44 2810.4IL8, CASP1, IL1B
14cuprophan449.3IL1B, IL1R1, IL1RAPL2, CASP1, TNFRSF1A
15infliximab44 50 1111.2TNFRSF1A, IL1RAPL2, IL1R1, CRP, IL1B
16pentoxifylline44 1110.1IL1RAPL2, IL1B, IL8, CASP1, IL1R1
17lxa4449.1IL1B, IL3, IL8
18il 10449.1IL3, IL1R1, IL1RAPL2, IL1B, IL8
19sulfasalazine28 44 50 1112.0IL1R1, IL1RAPL2, IL8, IL1B, CRP
20leukotriene b444 61 2411.0IL8, IL1B, IL1R1, IL1RAPL2, IL3
21anakinra44 1110.0IL1RAPL2, IL1R1, IL1B, CASP1, CRP, NLRP3
22sb 20358044 6110.0IL8, IL1B, CASP1, CRP, TNFRSF1A, IL1R1
23fmlp448.9IL1B, IL3, IL8, TNFRSF1A, IL1RAPL2
24methotrexate50 44 1110.9NLRP3, CRP, IL1B, IL1RAPL2, TNFRSF1A, IL1R1
25cyclophosphamide44 50 1110.9IL3, IL1R1, IL1RAPL2, CRP, FGFR2
26ivig448.8IL1RAPL2, IL1R1, IL3, CRP, IL1B, TNFRSF1A
27aspirin44 50 28 2411.8IL1R1, IL1RAPL2, CASP1, IL1B, CRP
28ribonucleic acid448.8FGFR2, CASP1, IL1B, IL1R1, TNFRSF1A, IL1RAPL2
29etanercept44 50 1110.8TNFRSF1A, IL1RAPL2, IL8, IL1B, CRP, IL1R1
30rantes448.8IL1RAPL2, IL1R1, TNFRSF1A, IL3, IL8, IL1B
31pge2448.7TNFRSF1A, CASP1, IL1B, IL1R1, IL1RAPL2, IL8
32cyclosporin a44 28 6110.7IL1R1, IL1RAPL2, TNFRSF1A, CASP1, IL8, IL3
33cisplatin44 50 61 1111.7IL3, FGFR2, IL1R1, TNFRSF1A, TP63, CASP1
34lactate448.5CASP1, IL8, IL1RAPL2, IL1R1, IL3, CRP
35actinomycin d448.5IL8, IL1B, CASP1, IL1RAPL2, IL3, TNFRSF1A
36neopterin448.4CRP, IL1B, IL8, IL1RAPL2, IL1R1, TNFRSF1A
37creatinine448.4IL1RAPL2, TNFRSF1A, IL3, CRP, IL1R1, CASP1
38dexamethasone44 50 28 1111.4IL1RAPL2, IL1R1, IL3, IL1B, CASP1, TNFRSF1A
39thymidine44 249.4IL3, IL1R1, IL1RAPL2, IL1B, TP63, FGFR2
40h2o2448.3IL1RAPL2, IL1R1, IL3, TNFRSF1A, IL8, CASP1
41nitric oxide44 24 1110.3FGFR2, IL1RAPL2, CASP1, IL1B, IL8, IL1R1
42endotoxin448.3IL8, IL1B, CRP, MEFV, TNFRSF1A, IL1R1
43n acetylcysteine448.2TNFRSF1A, FGFR2, IL1R1, IL8, IL1B, CRP
44cycloheximide448.1CRP, CASP1, IL1B, IL8, IL1RAPL2, IL1R1
45retinoic acid44 249.1IL1B, IL1R1, TNFRSF1A, IL1RAPL2, IL3, TP63
46testosterone44 61 24 1111.1FGFR2, IL1RAPL2, TP63, IL1R1, CASP1, CRP
47glutamate448.1TP63, IL1R1, IL1RAPL2, TNFRSF1A, FGFR2, GNB2L1
48threonine448.0IL1R1, IL3, TNFRSF1A, GNB2L1, IL1RAPL2, CASP1
49vegf447.7FGFR2, TP63, TNFRSF1A, IL1R1, IL1RAPL2, IL8
50tyrosine447.6IL3, CASP1, TP63, TNFRSF1A, IL1RAPL2, GNB2L1

GO Terms for genes affiliated with Wells Syndrome

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Cellular components related to Wells Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1NLRP3 inflammasome complexGO:0725599.7NLRP3, CASP1
2extracellular spaceGO:0056158.8IL1B, IL3, TNFRSF1A, CRP, IL8
3extracellular regionGO:0055767.7FGFR2, TNFRSF1A, IL3, IL1R1, IL8, IL1B

Biological processes related to Wells Syndrome according to GeneCards/GeneDecks:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-1 beta secretionGO:05071810.1CASP1, NLRP3
2response to ATPGO:03319810.1CASP1, IL1B
3cellular response to organic substanceGO:07131010.1IL1B, CASP1
4nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:03587210.0MEFV, CASP1, NLRP3
5squamous basal epithelial stem cell differentiation involved in prostate gland acinus developmentGO:06052910.0FGFR2, TP63
6negative regulation of inflammatory responseGO:05072810.0NLRP3, MEFV, TNFRSF1A
7interleukin-1 beta productionGO:03261110.0IL1B, CASP1, NLRP3
8cellular response to mechanical stimulusGO:0712609.9CASP1, IL1B, TNFRSF1A
9positive regulation of I-kappaB kinase/NF-kappaB signalingGO:0431239.7CASP1, IL1B, TNFRSF1A
10hair follicle morphogenesisGO:0310699.7FGFR2, TP63
11activation of cysteine-type endopeptidase activity involved in apoptotic processGO:0069199.7GNB2L1, CASP1, NLRP3
12response to hypoxiaGO:0016669.6TNFRSF1A, CASP1, CRP
13immune responseGO:0069559.4IL1B, IL8, IL1R1, IL3
14cytokine-mediated signaling pathwayGO:0192219.4IL1B, IL1RAPL2, TNFRSF1A
15innate immune responseGO:0450879.2MEFV, CASP1, NLRP3, FGFR2
16epithelial to mesenchymal transitionGO:0018379.1HNRNPAB, FGFR2
17inflammatory responseGO:0069549.0NLRP3, CRP, IL1B, IL8, MEFV, TNFRSF1A
18apoptotic processGO:0069158.9TNFRSF1A, TP63, IL1B, CASP1, NLRP3, FGFR2

Molecular functions related to Wells Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1interleukin-1 receptor activityGO:0049089.6IL1RAPL2, IL1R1
2cysteine-type endopeptidase activator activity involved in apoptotic processGO:0086569.4CASP1, GNB2L1
3protein bindingGO:0055157.4CRP, CASP1, NLRP3, IL1R1, TP63, TNFRSF1A

Products for genes affiliated with Wells Syndrome

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Sources for Wells Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet