MCID: WLL006
MIFTS: 54

Wells Syndrome malady

Rare diseases, Skin diseases categories

Aliases & Classifications for Wells Syndrome

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Sources:
41NIH Rare Diseases, 47Orphanet, 60UMLS, 34MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet, 25ICD10
See all sources

Wells Syndrome, Aliases & Descriptions:

Name: Wells Syndrome 41 47 60
Eosinophilic Cellulitis 41 47
 
Bullous Cellulitis with Eosinophilia 41
Wells' Syndrome 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases
Orphanet: 47 
Rare skin diseases


Characteristics (Orphanet epidemiological data):

47
wells syndrome:
Inheritance: Not applicable; Prevalence: <1/1000000 (Worldwide); Age of onset: Adult; Age of death: normal life expectancy


External Ids:

Orphanet47 901
MESH via Orphanet34 C536693
ICD10 via Orphanet26 L98.3
UMLS via Orphanet61 C0343101
ICD1025 L98.3

Summaries for Wells Syndrome

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NIH Rare Diseases:41 Wells syndrome is a rare eosinophilic disorder characterized by itchy, burning, red, and inflamed areas on the skin often on the lower arm or leg. the lesions may be single or multiple. they are usually red at first (looking like cellulitis) then change to brown red, to blue gray, then greenish gray. the lesions are usually painful and are sometimes associated with a fever. they typically heal without scarring within weeks to months; however they often recur. the cause of wells syndrome is unknown; but some researchers think that wells syndrome is an autoimmune reaction. last updated: 12/14/2011

MalaCards based summary: Wells Syndrome, also known as eosinophilic cellulitis, is related to hay-wells syndrome and muckle-wells syndrome, and has symptoms including edema, skin rash and pruritus. An important gene associated with Wells Syndrome is NLRP3 (NLR family, pyrin domain containing 3), and among its related pathways are TRAF Pathway and Monoamine Transport. The compounds as 101 and tlck have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and colon, and related mouse phenotypes are digestive/alimentary and liver/biliary system.

Wikipedia:63 Eosinophilic cellulitus (also known as \"Wells\' syndrome\" from George Crichton Wells who first... more...

Related Diseases for Wells Syndrome

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Diseases related to Wells Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 141)
idRelated DiseaseScoreTop Affiliating Genes
1hay-wells syndrome31.2TP63, FGFR2
2muckle-wells syndrome31.0IL1R1, MEFV, TNFRSF1A, IL1RAPL2, IL1B, CASP1
3ectodermal dysplasia30.8TNFRSF1A, TP63
4urticaria30.6CASP1, IL1RAPL2, NLRP3
5amyloidosis30.5MEFV, TNFRSF1A, CRP, IL1RAPL2
6secondary amyloidosis30.3MEFV, CRP
7vasculitis30.1MEFV, IL1RAPL2, CRP
8arthropathy30.0CRP, IL1RAPL2, IL1B, NLRP3
9systemic lupus erythematosus29.9TNFRSF1A, IL1R1, IL1RAPL2, CRP
10colitis29.9IL8, IL1B, IL1RAPL2, IL1R1
11familial cold autoinflammatory syndrome29.8NLRP3, CASP1, IL1B, IL1R1, MEFV, TNFRSF1A
12herpes simplex29.7CASP1, IL1RAPL2, FGFR2
13adenocarcinoma29.6CASP1, FGFR2, GNB2L1, TP63, IL1RAPL2
14ulcerative colitis29.5IL1R1, IL1RAPL2, IL1B, CRP, IL8, CASP1
15cellulitis10.6
16palindromic rheumatism10.6MEFV
17schnitzler syndrome10.6IL1R1
18polyarteritis nodosa10.6MEFV
19pericarditis10.5MEFV
20adult-onset still's disease10.5CRP
21leukemoid reaction10.5IL3
22felty's syndrome10.5IL3
23septic arthritis10.5CRP
24pyoderma gangrenosum10.5NLRP3, MEFV
25aseptic meningitis10.4IL1R1, NLRP3
26common cold10.4IL8
27periodic fever, familial10.4MEFV, TNFRSF1A
28bronchitis10.4CRP
29bacteriuria10.4CRP
30relapsing fever10.4MEFV, TNFRSF1A
31conjunctivitis10.4NLRP3, TNFRSF1A
32pleurisy10.4IL1B, MEFV
33familial mediterranean fever, ar10.4TNFRSF1A, NLRP3, MEFV
34blau syndrome10.4IL1B, NLRP3, MEFV
35cowpox10.3TNFRSF1A, CASP1
36exanthem10.3NLRP3, CRP
37bronchiolitis10.3IL8
38gout10.3IL1B, NLRP3
39polymyalgia rheumatica10.3IL1RAPL2, CRP
40spondylarthropathy10.3CRP, IL1RAPL2
41shigellosis10.3IL1R1, CASP1, IL1B
42myasthenic syndrome, slow-channel congenital10.3CRP, IL8
43malaria10.3IL1R1, IL1RAPL2, IL1B
44pulmonary disease, chronic obstructive10.3IL1B, CRP
45churg-strauss syndrome10.3
46viral meningitis10.3CRP, IL8
47extrinsic allergic alveolitis10.3TNFRSF1A, IL8
48rheumatic disease10.3IL1R1, MEFV, CRP
49gastritis10.3IL8, IL1RAPL2
50hcl-v10.3TNFRSF1A, IL3

Graphical network of the top 20 diseases related to Wells Syndrome:



Diseases related to wells syndrome

Symptoms for Wells Syndrome

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Symptoms:

 47 (show all 10)
  • cellulitis/panniculitis/pseudocellulitis/inflammation of subcutaneous tissue
  • cutaneous rash
  • pruritus/itching
  • cutaneous edema
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • eosinophils anomalies/hypereosinophilia
  • urticaria
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • follicular/erythematous/edematous papules/milium
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment

HPO human phenotypes related to Wells Syndrome:

(show all 7)
id Description Frequency HPO Source Accession
1 edema hallmark (90%) HP:0000969
2 skin rash hallmark (90%) HP:0000988
3 pruritus hallmark (90%) HP:0000989
4 abnormality of eosinophils hallmark (90%) HP:0001879
5 cellulitis hallmark (90%) HP:0100658
6 urticaria typical (50%) HP:0001025
7 abnormal blistering of the skin typical (50%) HP:0008066

Drugs & Therapeutics for Wells Syndrome

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Drug clinical trials:

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Search NIH Clinical Center for Wells Syndrome

Genetic Tests for Wells Syndrome

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Anatomical Context for Wells Syndrome

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MalaCards organs/tissues related to Wells Syndrome:

31
Skin, Brain, Colon, Kidney, Thyroid, Salivary gland, Myeloid, Monocytes, T cells, B cells, Neutrophil

Animal Models for Wells Syndrome or affiliated genes

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Publications for Wells Syndrome

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Articles related to Wells Syndrome:

(show top 50)    (show all 189)
idTitleAuthorsYear
1
Renal involvement in secondary amyloidosis of Muckle-Wells syndrome: marked improvement of renal function and reduction of proteinuria after therapy with human anti-interleukin-1I^ monoclonal antibody canakinumab. (24510061)
2014
2
Muckle wells syndrome associated with multifocal clinically isolated syndrome. (24618190)
2014
3
Life of Lesions in Eosinophilic Cellulitis (Wells' Syndrome)-A Condition That May Be Missed at First Sight. (25238447)
2014
4
Eosinophilic cellulitis (Wells syndrome) in a pediatric patient: a case report and review of the literature. (22611749)
2012
5
Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome. (21360513)
2011
6
NLRP3 E311K mutation in a large family with Muckle-Wells syndrome--description of a heterogeneous phenotype and response to treatment. (22146561)
2011
7
Hay-Wells syndrome of ectodermal dysplasia: A rare autosomal dominant disorder. (22346004)
2011
8
A patient with Wells' syndrome. (20500167)
2010
9
Improvement of sensoneurinal hearing loss in a patient with Muckle-Wells syndrome treated with anakinra]. (20135584)
2010
10
High responses of peripheral lymphocytes to mosquito salivary gland extracts in patients with Wells syndrome. (20542179)
2010
11
A case report of Wells' syndrome in a celiac patient. (20872333)
2010
12
Wells Syndrome with Multiorgan Involvement Mimicking Hypereosinophilic Syndrome. (20652113)
2009
13
Craniofacial and anthropometric phenotype in ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (Hay-Wells syndrome) in a cohort of 17 patients. (19676059)
2009
14
Quiz page. Muckle Wells syndrome. (18971008)
2008
15
Eosinophilic cellulitis (Wells' syndrome) in association with angioimmunoblastic lymphadenopathy. (17989892)
2007
16
Hay-wells syndrome of ectodermal dysplasia. (16444073)
2006
17
Wells syndrome: an enigmatic and therapeutically challenging disease. (17039661)
2006
18
Recovery from deafness in a patient with Muckle-Wells syndrome treated with anakinra. (16646042)
2006
19
A probable case of Muckle-Wells syndrome. (16556280)
2006
20
Rapp-Hodgkin ectodermal dysplasia syndrome: the clinical and molecular overlap with Hay-Wells syndrome. (16532463)
2006
21
Successful treatment of acute visual loss in Muckle-Wells syndrome with interleukin 1 receptor antagonist. (16014694)
2005
22
Bullous &quot;cellulitis&quot; with eosinophilia: case report and review of Wells' syndrome in childhood. (15995016)
2005
23
TNFRSF1A-associated periodic syndrome (TRAPS), Muckle-Wells syndrome (MWS) and renal amyloidosis. (12832748)
2003
24
Wells' syndrome: a clinical and histopathologic review of seven cases. (12581147)
2003
25
Herpes simplex virus type 2-associated eosinophilic cellulitis (Wells' syndrome). (12734477)
2003
26
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. (12815153)
2003
27
Wells syndrome. (14533832)
2003
28
New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes. (11992256)
2002
29
Nodular presentation of eosinophilic cellulitis (Wells' syndrome). (11722455)
2001
30
Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63. (11159940)
2001
31
Wells' syndrome (eosinophilic cellulitis): correlation between clinical activity, eosinophil levels, eosinophil cation protein and interleukin-5. (10215782)
1999
32
Genetic linkage of the Muckle-Wells syndrome to chromosome 1q44. (10486324)
1999
33
Circadian elevation of IL-6 levels in Muckle-Wells syndrome: a disorder of the neuro-immune axis? (9797932)
1998
34
Wells' syndrome associated with idiopathic hypereosinophilic syndrome. (9470919)
1997
35
Wells' syndrome responsive to PUVA therapy. (9349363)
1997
36
Toxocariasis and Wells' syndrome: a causal relationship? (9529550)
1997
37
Congenital Wells syndrome. (9263317)
1997
38
Recurrent urticarial skin eruption since infancy. Muckle-Wells syndrome (MWS). (7826101)
1995
39
The arthropathy of the Muckle-Wells syndrome. (8000753)
1994
40
Iritis and Wells' syndrome. (1459774)
1992
41
Wells' syndrome in children: varicella infection as a precipitating event. (2004004)
1991
42
Amyloid goiter and arthritides after kidney transplantation in a patient with systemic amyloidosis and Muckle-Wells syndrome. (2589249)
1989
43
Eosinophilic infiltration with flame figures. A distinctive tissue reaction seen in Wells' syndrome and other diseases. (3728877)
1986
44
Eosinophilic cellulitis (Wells' syndrome) (4015127)
1985
45
Recurrent granulomatous dermatitis with eosinophilia. Wells' syndrome. (6724778)
1984
46
Eosinophilic cellulitis (Wells' syndrome): histologic and clinical features in arthropod bite reactions. (6512050)
1984
47
Wells' syndrome: is there collagen damage in the flame figures? (6520258)
1984
48
Identification of amyloid A protein in a sporadic Muckle-Wells syndrome. N-terminal amino acid sequence after isolation from formalin-fixed tissue. (6406764)
1983
49
The Muckle-Wells syndrome and the major histocompatibility complex. (6857626)
1983
50
Wells' syndrome. Recurrent granulomatous dermatitis with eosinophilia. (443839)
1979

Variations for Wells Syndrome

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Expression for genes affiliated with Wells Syndrome

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Search GEO for disease gene expression data for Wells Syndrome.

Pathways for genes affiliated with Wells Syndrome

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Pathways related to Wells Syndrome according to GeneCards Suite gene sharing:

(show all 37)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.9CASP1, TNFRSF1A
2
Show member pathways
Serotonin Transporter Activity36
9.9IL1B, IL1R1
39.9CASP1, IL1B
4
Show member pathways
IL-1 Signaling Pathway36
IL1-mediated signaling events36
9.7IL1R1, IL1B, CASP1
59.6TNFRSF1A, IL1R1, IL1B
6
Show member pathways
9.6TNFRSF1A, IL1R1, IL1B
79.6TNFRSF1A, IL3, IL1R1
89.6IL1B, IL1R1, IL3
9
Show member pathways
9.5IL1B, IL3, TNFRSF1A
109.5IL8, GNB2L1
119.5IL1B, IL8, IL1R1
12
Show member pathways
Immune response MIF in innate immunity response58
9.5IL1B, IL8, IL1R1
139.5IL1R1, IL8, IL1B
149.5CASP1, IL1B, IL8
15
Show member pathways
9.5CASP1, IL1B, IL8
16
Show member pathways
9.5IL1R1, IL1B, FGFR2
179.4IL1B, IL8, IL3
189.4IL1B, IL8, IL3
19
Show member pathways
Apoptosis Modulation and Signaling36
Apoptosis36
9.4TNFRSF1A, TP63, IL1R1, CASP1
20
Show member pathways
9.3CASP1, IL1B, IL1R1, IL3
21
Show member pathways
9.3IL3, IL1R1, IL1B, CASP1
229.3NLRP3, CASP1, IL1B, IL8
239.2IL1B, IL8, IL1R1, TNFRSF1A
24
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
9.2TNFRSF1A, IL1R1, IL8, IL1B
25
Show member pathways
9.2TNFRSF1A, IL1R1, IL1B, FGFR2
26
Show member pathways
9.0NLRP3, CASP1, IL1B, IL8, MEFV
27
Show member pathways
9.0TNFRSF1A, IL3, IL1R1, IL1B, CASP1
28
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways58
Immune response IL 1 signaling pathway58
9.0IL1R1, IL8, IL1B, CASP1, NLRP3
29
Show member pathways
MAPK signaling pathway36
8.9TNFRSF1A, IL1R1, IL1B, CASP1, FGFR2
30
Show member pathways
8.8TNFRSF1A, IL3, IL1R1, IL1B, FGFR2
31
Show member pathways
8.8TNFRSF1A, IL3, IL1B, CASP1, FGFR2
32
Show member pathways
8.5GNB2L1, TNFRSF1A, IL8, IL1B, CASP1, NLRP3
33
Show member pathways
8.4TNFRSF1A, IL3, IL1R1, IL8, IL1B, FGFR2
34
Show member pathways
8.4TNFRSF1A, IL3, IL1R1, IL8, IL1B, FGFR2
35
Show member pathways
8.2TNFRSF1A, IL3, IL1R1, IL8, IL1B, CASP1
36
Show member pathways
8.2TNFRSF1A, IL3, IL1R1, IL8, IL1B, CASP1
37
Show member pathways
7.9GNB2L1, TNFRSF1A, IL3, IL1R1, IL8, IL1B

Compounds for genes affiliated with Wells Syndrome

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Compounds related to Wells Syndrome according to GeneCards Suite gene sharing:

(show top 50)    (show all 151)
idCompoundScoreTop Affiliating Genes
1as 10143 5910.7IL1B, CASP1, IL1R1, IL3
2tlck439.7IL8, IL1B, CASP1
3mevalonate439.7TNFRSF1A, MEFV, CASP1, NLRP3
4p005439.6IL1R1, CRP, TP63, TNFRSF1A
5tenidap43 2810.5IL1B, IL1R1, CRP
6diphenyleneiodonium439.5CASP1, IL1B, IL8, IL1R1
7peptidoglycan43 2810.5CASP1, IL1B, IL8, IL1R1
8poly(i-c)439.5IL8, CASP1, IL1B, IL3
9leflunomide43 49 1211.5IL1B, IL1RAPL2, IL1R1, TNFRSF1A
10adalimumab43 49 1211.4IL1RAPL2, TNFRSF1A, IL1R1, CRP
11monosodium urate439.4IL1B, IL8, IL1R1, IL1RAPL2
12polysulfone439.4IL1B, IL1RAPL2, IL1R1, CRP
13muramyl dipeptide43 2810.4IL8, CASP1, IL1B
14cuprophan439.3IL1B, IL1R1, IL1RAPL2, CASP1, TNFRSF1A
15infliximab43 49 1211.2TNFRSF1A, IL1RAPL2, IL1R1, CRP, IL1B
16pentoxifylline43 1210.1IL1RAPL2, IL1B, IL8, CASP1, IL1R1
17lxa4439.1IL1B, IL3, IL8
18il 10439.1IL3, IL1R1, IL1RAPL2, IL1B, IL8
19sulfasalazine28 43 49 1212.0IL1R1, IL1RAPL2, IL8, IL1B, CRP
20leukotriene b443 59 2411.0IL8, IL1B, IL1R1, IL1RAPL2, IL3
21anakinra43 1210.0IL1RAPL2, IL1R1, IL1B, CASP1, CRP, NLRP3
22sb 20358043 5910.0IL8, IL1B, CASP1, CRP, TNFRSF1A, IL1R1
23fmlp438.9IL1B, IL3, IL8, TNFRSF1A, IL1RAPL2
24methotrexate49 43 1210.9NLRP3, CRP, IL1B, IL1RAPL2, TNFRSF1A, IL1R1
25cyclophosphamide43 49 1210.9IL3, IL1R1, IL1RAPL2, CRP, FGFR2
26ivig438.8IL1RAPL2, IL1R1, IL3, CRP, IL1B, TNFRSF1A
27aspirin43 49 28 2411.8IL1R1, IL1RAPL2, CASP1, IL1B, CRP
28ribonucleic acid438.8FGFR2, CASP1, IL1B, IL1R1, TNFRSF1A, IL1RAPL2
29etanercept43 49 1210.8TNFRSF1A, IL1RAPL2, IL8, IL1B, CRP, IL1R1
30rantes438.8IL1RAPL2, IL1R1, TNFRSF1A, IL3, IL8, IL1B
31pge2438.7TNFRSF1A, CASP1, IL1B, IL1R1, IL1RAPL2, IL8
32cyclosporin a43 28 5910.7IL1R1, IL1RAPL2, TNFRSF1A, CASP1, IL8, IL3
33cisplatin43 49 59 1211.7IL3, FGFR2, IL1R1, TNFRSF1A, TP63, CASP1
34lactate438.5CASP1, IL8, IL1RAPL2, IL1R1, IL3, CRP
35actinomycin d438.5IL8, IL1B, CASP1, IL1RAPL2, IL3, TNFRSF1A
36neopterin438.4CRP, IL1B, IL8, IL1RAPL2, IL1R1, TNFRSF1A
37creatinine438.4IL1RAPL2, TNFRSF1A, IL3, CRP, IL1R1, CASP1
38dexamethasone43 49 28 1211.4IL1RAPL2, IL1R1, IL3, IL1B, CASP1, TNFRSF1A
39thymidine43 249.4IL3, IL1R1, IL1RAPL2, IL1B, TP63, FGFR2
40h2o2438.3IL1RAPL2, IL1R1, IL3, TNFRSF1A, IL8, CASP1
41nitric oxide43 24 1210.3FGFR2, IL1RAPL2, CASP1, IL1B, IL8, IL1R1
42endotoxin438.3IL8, IL1B, CRP, MEFV, TNFRSF1A, IL1R1
43n acetylcysteine438.2TNFRSF1A, FGFR2, IL1R1, IL8, IL1B, CRP
44cycloheximide438.1CRP, CASP1, IL1B, IL8, IL1RAPL2, IL1R1
45retinoic acid43 249.1IL1B, IL1R1, TNFRSF1A, IL1RAPL2, IL3, TP63
46testosterone43 59 24 1211.1FGFR2, IL1RAPL2, TP63, IL1R1, CASP1, CRP
47glutamate438.1TP63, IL1R1, IL1RAPL2, TNFRSF1A, FGFR2, GNB2L1
48threonine438.0IL1R1, IL3, TNFRSF1A, GNB2L1, IL1RAPL2, CASP1
49vegf437.7FGFR2, TP63, TNFRSF1A, IL1R1, IL1RAPL2, IL8
50tyrosine437.6IL3, CASP1, TP63, TNFRSF1A, IL1RAPL2, GNB2L1

GO Terms for genes affiliated with Wells Syndrome

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Cellular components related to Wells Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1NLRP3 inflammasome complexGO:00725599.7NLRP3, CASP1
2extracellular spaceGO:00056158.8IL3, IL8, IL1B, CRP, TNFRSF1A
3extracellular regionGO:00055767.7FGFR2, TNFRSF1A, IL3, IL1R1, IL8, IL1B

Biological processes related to Wells Syndrome according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-1 beta secretionGO:005071810.1CASP1, NLRP3
2response to ATPGO:003319810.1CASP1, IL1B
3cellular response to organic substanceGO:007131010.1IL1B, CASP1
4nucleotide-binding domain, leucine rich repeat containing receptor signaling pathwayGO:003587210.0MEFV, CASP1, NLRP3
5squamous basal epithelial stem cell differentiation involved in prostate gland acinus developmentGO:006052910.0FGFR2, TP63
6negative regulation of inflammatory responseGO:005072810.0NLRP3, MEFV, TNFRSF1A
7interleukin-1 beta productionGO:003261110.0IL1B, CASP1, NLRP3
8cellular response to mechanical stimulusGO:00712609.9CASP1, IL1B, TNFRSF1A
9positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.7CASP1, IL1B, TNFRSF1A
10hair follicle morphogenesisGO:00310699.7FGFR2, TP63
11activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.7GNB2L1, CASP1, NLRP3
12response to hypoxiaGO:00016669.6TNFRSF1A, CASP1, CRP
13immune responseGO:00069559.4IL1B, IL8, IL1R1, IL3
14cytokine-mediated signaling pathwayGO:00192219.4IL1B, IL1RAPL2, TNFRSF1A
15innate immune responseGO:00450879.2MEFV, CASP1, NLRP3, FGFR2
16epithelial to mesenchymal transitionGO:00018379.1HNRNPAB, FGFR2
17inflammatory responseGO:00069549.0NLRP3, CRP, IL1B, IL8, MEFV, TNFRSF1A
18apoptotic processGO:00069158.9TNFRSF1A, TP63, IL1B, CASP1, NLRP3, FGFR2

Molecular functions related to Wells Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1interleukin-1 receptor activityGO:00049089.6IL1RAPL2, IL1R1
2cysteine-type endopeptidase activator activity involved in apoptotic processGO:00086569.4CASP1, GNB2L1
3protein bindingGO:00055157.4TNFRSF1A, TP63, IL1R1, IL8, CASP1, CRP

Products for genes affiliated with Wells Syndrome

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Sources for Wells Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet