MCID: WRN003
MIFTS: 42

Wernicke Encephalopathy malady

Categories: Metabolic diseases, Neuronal diseases

Aliases & Classifications for Wernicke Encephalopathy

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Aliases & Descriptions for Wernicke Encephalopathy:

Name: Wernicke Encephalopathy 11 13 48 37 66
Wernicke-Korsakoff Syndrome 66
 
Wernicke's Encephalopathy 11
Wernicke's Disease 11

Classifications:



External Ids:

Disease Ontology11 DOID:2384
ICD1028 E51.2
MeSH37 D014899

Summaries for Wernicke Encephalopathy

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Disease Ontology:11 A brain disease that is characterised by the presence of neurological symptoms of ophthalmoplegia, ataxia, and confusion caused by biochemical lesions of the central nervous system after exhaustion of b-vitamin reserves, in particular thiamine (vitamin b1).

MalaCards based summary: Wernicke Encephalopathy, also known as wernicke-korsakoff syndrome, is related to cerebral beriberi and encephalopathy, and has symptoms including ataxia and ophthalmoplegia. An important gene associated with Wernicke Encephalopathy is TKT (Transketolase), and among its related pathways are Amyotrophic lateral sclerosis (ALS) and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs thiamine mononitrate and thiamine hydrochloride have been mentioned in the context of this disorder. Affiliated tissues include brain, lung and liver, and related mouse phenotypes are vision/eye and normal.

Related Diseases for Wernicke Encephalopathy

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Diseases related to Wernicke Encephalopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idRelated DiseaseScoreTop Affiliating Genes
1cerebral beriberi11.1
2encephalopathy10.9
3ependymoblastoma10.3GFAP, INA
4uterine corpus epithelioid leiomyosarcoma10.3GFAP, INA
5adult central nervous system primitive neuroectodermal neoplasm10.2GFAP, INA
6obesity10.1
7lymphoma10.1
8pancreatitis10.1
9wernicke-korsakoff syndrome10.1
10acute pancreatitis10.1
11dental pulp disease10.0GFAP, GLUL
12polycystic kidney disease 210.0GFAP, MAPT
13pick disease10.0INA, MAPT
14creutzfeldt-jakob disease10.0
15liver cirrhosis10.0
16morbid obesity10.0
17cerebritis10.0
18central pontine myelinolysis10.0
19neuropathy10.0
20chronic intestinal vascular insufficiency9.9GFAP, MAPT
21newborn respiratory distress syndrome9.8GFAP, SLC1A2
22neuroblastoma9.8
23hepatocellular carcinoma9.8
24anorexia nervosa9.8
25pancreatic cancer9.8
26acute liver failure9.8
27crohn's disease9.8
28leukemia9.8
29sensorineural hearing loss9.8
30stomach cancer9.8
31beriberi9.8
32diabetic ketoacidosis9.8
33retinitis9.8
34leber hereditary optic neuropathy9.8
35t-cell leukemia9.8
36neuronitis9.8
37pellagra9.8
38duodenitis9.8
39encephalitis9.8
40cyclic vomiting syndrome9.8
41tremor9.8
42ovarian mucinous cystadenocarcinoma9.8GFAP, SLC1A2
43purpura9.8GFAP, GLUL
44neurogenic bowel9.8GLUL, SLC1A2
45atrophic rhinitis9.7GLUL, SLC1A2
46testicular lymphoma9.7GFAP, SLC1A2
47angiomyolipoma9.6GFAP, MAPT
48mucopolysaccharidosis iii9.5MAPT, SLC1A2
49myoclonic encephalopathy of infants9.2MAPT, SLC1A2, SLC1A3
50long qt syndrome 58.4GFAP, INA, MAPT, SLC1A2, SLC1A3

Graphical network of the top 20 diseases related to Wernicke Encephalopathy:



Diseases related to wernicke encephalopathy

Symptoms for Wernicke Encephalopathy

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UMLS symptoms related to Wernicke Encephalopathy:


ataxia, ophthalmoplegia

Drugs & Therapeutics for Wernicke Encephalopathy

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Drugs for Wernicke Encephalopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1FolateNutraceuticalPhase 4, Phase 34143
2
ThiamineNutraceuticalPhase 4, Phase 39559-43-81130
Synonyms:
100660-17-1
115461-66-0
1sbr
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydrox yethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethylthiazolium chloride, monohydrochloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride
3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
3-(4-AMINO-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium
3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride
3[(4-Amino-2-methyl-5-pyrimidinyl)-methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
55463-15-5
57777-32-9
59-43-8
67-03-8
AC-11683
AC1L1ASK
AC1L1LOC
AC1LAODT
AC1Q4V9Q
AI3-18993
AKOS000668650
AR-1L8201
Aneurin
Aneurine
Antiberiberi factor
Apatate drape
Apate drops
B-Amin
BAS 00266240
BPBio1_000686
BSPBio_000622
Beatine
Bedome
Begiolan
Beivon
Benerva
Bequin
Berin
Betabion
Betalin S
Betaxin
Bethiamin
Bethiazine
Beuion
Bevitex
Bevitine
Bewon
Biamine
Bithiamin
Biuno
Bivatin
Bivita
C00378
C12H17N4OS
CCRIS 1906
CCRIS 5823
CHEBI:18385
CHEBI:33283
CHEBI:49105
CHEMBL1547
CHEMBL1588
CID1130
CID517305
CID6042
Cernevit-12
Chloride-hydrochloride salt of thiamine
Clotiamina
D08580
DB00152
EINECS 200-425-3
EINECS 200-641-8
Eskapen
Eskaphen
FEMA No. 3322
 
HSDB 220
Hybee
I14-14339
LS-3226
LT00233141
Lixa-beta
MLS001304099
Metabolin
MolPort-000-722-048
MolPort-001-920-086
MolPort-002-052-059
NChemBio.2007.13-comp10
NSC 36226
NSC36226
Oryzanin
Oryzanine
Prestwick0_000631
Prestwick1_000631
Prestwick2_000631
Prestwick3_000631
SBB058094
SMP1_000084
SMR000718788
SPBio_002841
ST095175
Slowten
THD
THIAMIN, VITAMIN B1
Thiadoxine
Thiamin
Thiamin dichloride
Thiaminal
Thiamine
Thiamine (INN)
Thiamine HCL
Thiamine [INN:BAN]
Thiamine chloride
Thiamine chloride hydrochloride
Thiamine dichloride
Thiamine hydrochloride [JAN]
Thiamine monochloride
Thiamine monohydrochloride
Thiamine, chloride
Thiamine, chloride, hydrochloride
Thiamine, monohydrochloride
Thiaminium
Thiaminium chloride hydrochloride
Thiaminum
Thiaminum [INN-Latin]
Thiamol
Thiavit
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethyl, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1)
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-chloride
Tiamidon
Tiamina
Tiamina [INN-Spanish]
Tiaminal
TimTec1_000613
Trophite
UNII-X66NSO3N35
VIB
Vetalin S
Vinothiam
Vitamin B1
Vitamin B1 (TN)
Vitamin B1 hydrochloride (VAN)
Vitaneurin
Vitaneuron
ZINC00049153
[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methylpyrimidin-4-yl]azanium dichloride
bmse000274
nchembio.121-comp5
thiamin
thiamine
thiamine(1+)
thiamine(1+) ion
thiaminium
vitamin B1
vitamin b1(thiamine)
3
Folic AcidNutraceuticalPhase 4, Phase 3414359-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
4
PromethazinePhase 321760-87-74927
Synonyms:
(2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
(2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine
(Dimethylamino-2-propyl-10-phenothiazine hydrochloride
10-(2-(Dimethylamino)-2-methylethyl)phenothiazine
10-(2-(Dimethylamino)propyl)phenothiazine
10-(2-Dimethylaminopropyl)phenothiazine
10-[2-(Dimethylamino)propyl]phenothiazine
10-[2-(dimethylamino)Propyl]phenothiazine
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl- (9CI)
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, radical ion(1+)
3277 RP
3389 R.p.
38878-40-9
4-27-00-01253 (Beilstein Handbook Reference)
4182 R.p.
60-87-7
73745-50-3
A-91033
AB00053535
AC-15939
AC1L1J92
Antiallersin
Aprobit
Avomine
BPBio1_000744
BRN 0088554
BSPBio_000676
BSPBio_002777
C07404
CCRIS 7056
CHEBI:8461
CHEMBL643
CID4927
Camergan
D00494
DB01069
Dimapp
Dimethylamino-isopropyl-phenthiazin
Dimethylamino-isopropyl-phenthiazin [German]
Diphergan
Diprazin
Diprazine
Diprozin
DivK1c_000005
EINECS 200-489-2
Fargan
Fenazil
Fenetazina
Fenetazine
Genphen
HMS2089E08
HSDB 3173
Hiberna
Histargan
IDI1_000005
Iergigan
InChI=1/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3
Isophenergan
Isopromethazine
KBio1_000005
KBio2_001348
KBio2_003916
KBio2_006484
KBio3_001997
KBioGR_001697
KBioSS_001348
L000495
LS-264
Lercigan
Lergigan
Lilly 01516
Lilly 1516
Lopac0_000899
Metaryl
MolPort-001-783-684
N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine
N,N,╬▒-trimethyl-10H-phenothiazine-10-ethanamine
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine
 
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine hydrochloride
N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine
N-(2'-dimethylamino-2'-Methyl)ethylphenothiazine
N-Dimethylamino-2-methylethyl thiodiphenylamine
NCGC00015817-10
NCGC00089735-02
NCGC00089735-03
NCI-C60673
NCI60_001878
NINDS_000005
NSC 30321
NSC30321
Oprea1_758749
PROMETHAZINE (SEE ALSO PROMETHAZINE HYDROCHLORIDE 58-33-3)
Pelpica
Phargan
Phenargan
Phenerzine
Phenoject-50
Phensedyl
Pilothia
Pilpophen
Pipolphene
Prestwick0_000888
Prestwick1_000888
Prestwick2_000888
Prestwick3_000888
Pro-50
Proazaimine
Proazamine
Procit
Promacot
Promazinamide
Promergan
Promesan
Prometasin
Prometazin
Prometazina
Prometazina [INN-Spanish]
Prometazine
Prometh
Promethacon
Promethaine
Promethazin
Promethazine
Promethazine (JAN/INN)
Promethazine [INN:BAN]
PromethazineHcl
Promethazinum
Promethazinum [INN-Latin]
Promethegan
Promethiazine
Promezathine
Prorex
Protazine
Prothazin
Prothazine
Provigan
Pyrethia
Pyrethiazine
RP 3277
Remsed
Romergan
Rumergan
SKF 1498
SPBio_000799
SPBio_002895
Spectrum2_000840
Spectrum3_001019
Spectrum4_001149
Spectrum5_000977
Spectrum_000868
Tanidil
Thiergan
UNII-FF28EJQ494
Valergine
Vallergine
WLN: T C666 BN ISJ B1Y1&N1&1
WY 509
Zipan-25
promethazine
5
Histamine PhosphatePhase 3100851-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
 
EINECS 200-118-4
H0147
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
6
histaminePhase 3100975614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
7
DiphenhydraminePhase 321758-73-1, 147-24-03100
Synonyms:
147-24-0
147-24-0 (HYDROCHLORIDE)
2-(Benzhydryloxy)-N,N-dimethylethylamine
2-(Benzhydryloxy)-N,N-dimethylethylamine, hydrochloride
2-(Diphenylmethoxy)-N,N-dimethylethylamine
2-(diphenylmethoxy)-N,N-dimethylethanamine
2-Diphenylmethoxy-N,N-dimethylethylamine
2-[(diphenylmethyl)oxy]-N,N-dimethylethanamine
2-benzhydryloxy-N,N-dimethylethanamine
2-benzhydryloxyethyl-N,N-dimethylammonium
2-diphenylmethoxy-N,N-demthylethanamine
2PM
58-73-1
88637-37-0 (citrate (1:1))
AB00053460
AC-13704
AC1L1F65
AKOS003658554
Aleryl
Alledryl
Aller-Med
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CAS-147-24-0
CCRIS 1959
CHEBI:127629
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CHEMBL657
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D00300
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Diphenhydramine
Diphenhydramine (JP15/INN)
Diphenhydramine Base
Diphenhydramine HCl
Diphenhydramine [INN:BAN:JAN]
Diphenhydraminum
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Diphenylhydramin
Diphenylhydramine
DivK1c_000368
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Dormarex 2
Dryistan
Drylistan
Dylamon
EINECS 200-396-7
Etanautine
FAR 90X2
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HMS2089E06
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Histaxin
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I14-6749
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KBio1_000368
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N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE
NCGC00015335-01
NCGC00015335-02
NCGC00015335-03
NCGC00015335-10
NCGC00024414-03
NCGC00024414-04
NCI60_002916
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beta-Dimethylaminoethanol diphenylmethyl ether
beta-Dimethylaminoethyl benzhydryl ether
beta-Dimethylaminoethylbenzhydrylether
beta-dimethylaminoethyl benzhydryl ether
diphenhydramine
nchembio747-comp18
╬▓-dimethylaminoethyl benzhydryl ether
8
Etanercept391185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
9pyruvateNutraceutical34

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1Optimum Thiamine Intervention (OpTIn) TrialRecruitingNCT02788552Phase 4
2Cesium-131 Seed Brachytherapy Plus Subtotal Resection for Lung Cancer PatientsRecruitingNCT01757158Phase 4
3Does Thiamine Help Vomiting and Nausea in Pregnancy?TerminatedNCT00861523Phase 3
4Transcranial Magnetic Stimulation for "Voices"CompletedNCT00308997Phase 2
5Bilateral Repetitive Transcranial Magnetic Stimulation for Auditory HallucinationsRecruitingNCT00567281Phase 2
6Models of Disordered Knowledge and Memory Systems in Dementia and Related DisordersCompletedNCT00004557
7From Uncomplicated Alcoholism to Korsakoff's SyndromeRecruitingNCT01455207
8MRI and Diffusion Imaging of Eloquent Brain Areas to Optimize Brain Tumor Resection PlanningRecruitingNCT01534104
9A Study To Evaluate The Efficacy Of Enbrel (REGISTERED) Etanercept Over A Period Of 12 Months In The Routine Treatment Of Patients With Rheumatoid Arthritis, Axial Spondyloarthritis, Psoriatic Arthritis, Or Plaque Psoriasis.RecruitingNCT02486302
10The Effect of tDCS on Subcortical Brain FunctioningEnrolling by invitationNCT01602276
11Study of the Effect of Transcranial Stimulations in Aphasic Subject Within a Year of Their StrokeNot yet recruitingNCT02101398

Search NIH Clinical Center for Wernicke Encephalopathy

Inferred drug relations via UMLS66/NDF-RT44:


Cochrane evidence based reviews: wernicke encephalopathy

Genetic Tests for Wernicke Encephalopathy

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Anatomical Context for Wernicke Encephalopathy

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MalaCards organs/tissues related to Wernicke Encephalopathy:

34
Brain, Lung, Liver, Occipital lobe, T cells

Animal Models for Wernicke Encephalopathy or affiliated genes

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MGI Mouse Phenotypes related to Wernicke Encephalopathy:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.2GFAP, MAPT, SLC1A3, TKT
2MP:00028737.4GFAP, GLUL, INA, MAPT, SLC1A2
3MP:00107687.3GFAP, GLUL, MAPT, SLC1A2, SLC1A3, TKT
4MP:00053867.2GFAP, GLUL, MAPT, SLC1A2, SLC1A3, TKT
5MP:00036316.7GFAP, GLUL, INA, MAPT, SLC1A2, SLC1A3

Publications for Wernicke Encephalopathy

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Articles related to Wernicke Encephalopathy:

(show top 50)    (show all 168)
idTitleAuthorsYear
1
Cerebral salt-wasting syndrome in a child with Wernicke encephalopathy treated with fludrocortisone therapy: A case report. (27603336)
2016
2
Magnetic Resonance Imaging and H-proton Spectroscopy assessment of maternal and foetal brains in a case of pregnancy-associated Wernicke encephalopathy. (27624910)
2016
3
Sleeve Gastrectomy and Wernicke Encephalopathy. (27415978)
2016
4
Wernicke encephalopathy in a patient with liver failure: Clinical case report. (27399058)
2016
5
Complex ophthalmoplaegia denoting Wernicke encephalopathy in a non-alcoholic individual. (25828145)
2015
6
Wernicke Encephalopathy: a Future Problem Even After Sleeve Gastrectomy? A Systematic Literature Review. (26476834)
2015
7
Wernicke Encephalopathy and Sleeve Gastrectomy: A Case Report and Literature Review. (26539904)
2015
8
Need for early diagnosis of mental and mobility changes in Wernicke encephalopathy. (25539041)
2014
9
Imaging-based diagnosis of wernicke encephalopathy: a case report. (25717447)
2014
10
Wernicke encephalopathy and ethanol-related syndromes. (24745886)
2014
11
Recurrent Wernicke encephalopathy in an adolescent female following laparoscopic gastric bypass surgery. (23559489)
2013
12
Wernicke Encephalopathy in Pediatric Neuro-oncology: Presentation of 2 Cases and Review of Literature. (24293308)
2013
13
Acute bilateral deafness as the first symptom of Wernicke encephalopathy. (22300936)
2012
14
Wernicke encephalopathy in a non-alcoholic patient with metastatic CNS lymphoma and new-onset occipital lobe seizures. (23224489)
2012
15
MR Imaging: an increasingly important tool in the early diagnosis of Wernicke encephalopathy. (22576900)
2012
16
Glucose before thiamine for Wernicke encephalopathy: a literature review. (22104258)
2012
17
Thiamine deficiency after bariatric surgery may lead to Wernicke encephalopathy. (23240377)
2012
18
Wernicke encephalopathy presenting in a patient with severe acute pancreatitis. (22233960)
2012
19
Wernicke encephalopathy after pancreaticoduodenectomy for pancreatic cancer. (21926559)
2011
20
Forniceal involvement in Wernicke encephalopathy. (22095970)
2011
21
Wernicke encephalopathy after gastrointestinal surgery for cancer: causes of diagnostic failure or delay. (21244301)
2011
22
Non-Alcoholic Wernicke Encephalopathy: MR Imaging and Review of the Literature. (24148532)
2010
23
Teaching NeuroImages: The full-blown neuroimaging of Wernicke encephalopathy. (20142624)
2010
24
Loss of astrocytic glutamate transporters in Wernicke encephalopathy. (19565658)
2010
25
Wernicke encephalopathy complicating hyperemesis gravidarum: a case report. (19913987)
2010
26
Teaching NeuroImages: the full-blown neuroimaging of Wernicke encephalopathy. (19487646)
2009
27
Wernicke encephalopathy in alcoholics with diabetic ketoacidosis. (19571457)
2009
28
MR imaging can predict the development of nonalcoholic Wernicke encephalopathy. (18566012)
2008
29
Teaching NeuroImage: Diverse MRI signal intensities with Wernicke encephalopathy. (18391151)
2008
30
Hearing and seeing: Unusual early signs of Wernicke encephalopathy. (18725598)
2008
31
Metronidazole-induced and Wernicke encephalopathy: two different entities sharing the same metabolic pathway? (18566011)
2008
32
Wernicke encephalopathy: MR findings at clinical presentation in twenty-six alcoholic and nonalcoholic patients. (17698536)
2007
33
Wernicke encephalopathy complicating lymphoma therapy: case report and literature review. (17639753)
2007
34
MRI findings of Wernicke encephalopathy revisited due to hunger strike. (16085381)
2006
35
Wernicke encephalopathy in infants. (16148619)
2005
36
Wernicke encephalopathy. (15006870)
2004
37
Wernicke encephalopathy - a severe neurological complication in a clinically inactive Crohn's disease. (14530629)
2003
38
Proton MR spectroscopy in Wernicke encephalopathy. (12748100)
2003
39
Magnetic resonance imaging as a diagnostic adjunct to Wernicke encephalopathy in the ED. (14574661)
2003
40
Diffusion abnormalities and Wernicke encephalopathy. (12601128)
2003
41
Diffusion abnormalities in patients with Wernicke encephalopathy. (11865152)
2002
42
Proton MR spectroscopy of Wernicke encephalopathy. (12427642)
2002
43
Diffusion-weighted MR in reversible wernicke encephalopathy. (11760803)
2001
44
Wernicke encephalopathy. (10714669)
2000
45
Wernicke encephalopathy: MR findings in two patients. (10525877)
1999
46
Thiamine before glucose to prevent Wernicke encephalopathy: examining the conventional wisdom. (9486750)
1998
47
Gestational thyrotoxicosis manifesting as wernicke encephalopathy: a case report. (9279523)
1997
48
Fluid attenuated inversion recovery (FLAIR) imaging in acute Wernicke encephalopathy. (8850375)
1995
49
Hypothermia, Wernicke encephalopathy and multiple sclerosis. (1481652)
1992
50
Wernicke encephalopathy: MR findings in five patients. (2120991)
1990

Variations for Wernicke Encephalopathy

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Expression for genes affiliated with Wernicke Encephalopathy

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Search GEO for disease gene expression data for Wernicke Encephalopathy.

Pathways for genes affiliated with Wernicke Encephalopathy

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GO Terms for genes affiliated with Wernicke Encephalopathy

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Cellular components related to Wernicke Encephalopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmic ribonucleoprotein granuleGO:00364649.7INA, MAPT
2intermediate filament cytoskeletonGO:00451119.6GFAP, INA
3glial cell projectionGO:00973869.6GFAP, GLUL
4cell projectionGO:00429958.6GFAP, GLUL, SLC1A3
5cell bodyGO:00442978.2GFAP, GLUL, MAPT
6myelin sheathGO:00432098.1GFAP, GLUL, INA, TKT

Biological processes related to Wernicke Encephalopathy according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1D-aspartate importGO:007077910.1SLC1A2, SLC1A3
2L-glutamate importGO:005193810.1SLC1A2, SLC1A3
3L-glutamate transmembrane transportGO:008971110.0SLC1A2, SLC1A3
4amino acid transmembrane transportGO:000333310.0SLC1A2, SLC1A3
5L-glutamate transportGO:001581310.0SLC1A2, SLC1A3
6glutamate secretionGO:00140479.7SLC1A2, SLC1A3
7glutamate metabolic processGO:00065369.7GLUL, SLC1A3
8neurotransmitter uptakeGO:00015049.6GLUL, SLC1A3
9response to light stimulusGO:00094169.5SLC1A2, SLC1A3
10ion transportGO:00068119.4SLC1A2, SLC1A3
11response to woundingGO:00096118.9GFAP, SLC1A2, SLC1A3

Molecular functions related to Wernicke Encephalopathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1high-affinity glutamate transmembrane transporter activityGO:000531410.1SLC1A2, SLC1A3
2L-glutamate transmembrane transporter activityGO:000531310.0SLC1A2, SLC1A3
3amino acid transmembrane transporter activityGO:001517110.0SLC1A2, SLC1A3
4glutamate bindingGO:00165959.4GLUL, SLC1A3
5structural constituent of cytoskeletonGO:00052008.9GFAP, INA, MAPT

Sources for Wernicke Encephalopathy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet