MCID: WST005
MIFTS: 50

West Nile Virus malady

Categories: Genetic diseases, Rare diseases, Infectious diseases

Aliases & Classifications for West Nile Virus

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Aliases & Descriptions for West Nile Virus:

Name: West Nile Virus 50 46 25 36
West Nile Virus, Susceptibility to 12
 
West Nile Viral Infection 66

Classifications:



External Ids:

OMIM50 610379

Summaries for West Nile Virus

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MedlinePlus:36 West nile virus (wnv) is an infectious disease that first appeared in the united states in 1999. infected mosquitoes spread the virus that causes it. people who get wnv usually have no symptoms or mild symptoms. the symptoms include a fever, headache, body aches, skin rash, and swollen lymph glands. they can last a few days to several weeks, and usually go away on their own. if west nile virus enters the brain, however, it can be life-threatening. it may cause inflammation of the brain, called encephalitis, or inflammation of the tissue that surrounds the brain and spinal cord, called meningitis. a physical exam, health history and laboratory tests can diagnose it. older people and those with weakened immune systems are most at risk. there are no specific vaccines or treatments for human wnv disease. the best way to avoid wnv is to prevent mosquito bites: use insect repellent get rid of mosquito breeding sites by emptying standing water from flower pots, buckets or barrels stay indoors between dusk and dawn, when mosquitoes are most active use screens on windows to keep mosquitoes out nih: national institute of allergy and infectious diseases

MalaCards based summary: West Nile Virus, also known as west nile virus, susceptibility to, is related to hiv-1 and hepatitis c virus, and has symptoms including back pain, headache and pain. An important gene associated with West Nile Virus is CCR5 (C-C Motif Chemokine Receptor 5 (Gene/Pseudogene)), and among its related pathways are Osteoblast Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include brain, testes and skin, and related mouse phenotypes are neoplasm and hematopoietic system.

OMIM:50 WNV is an enveloped, neurotropic, single-stranded sense RNA flavivirus that is naturally maintained in a zoonotic cycle... (610379) more...

Related Diseases for West Nile Virus

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Diseases related to West Nile Virus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 87)
idRelated DiseaseScoreTop Affiliating Genes
1hiv-129.1CCR5, CD209, CLEC4M, ITGAV, ITGB3, TLR3
2hepatitis c virus29.1CCR5, CLEC4M, DDX58, IFITM1, IRF3, RSAD2
3nervous system disease28.9CD209, DDX58, IFNA1, STAT1, TLR3
4west nile fever11.3
5west nile encephalitis11.2
6encephalitis10.8
7japanese encephalitis10.5
8st. louis encephalitis10.5
9crater-like holes of optic disc10.5CD209, IFITM3
10meningoencephalitis10.4
11chorioretinitis10.4
12meningitis10.3
13kunjin encephalitis10.3
14retinitis10.3
15poliomyelitis10.3
16tick-borne encephalitis10.2
17neuronitis10.2
18mastocytosis cutaneous with short stature conductive hearing loss and microtia10.1CD209, ITGB3, MX1
19eastern equine encephalitis10.1
20murray valley encephalitis10.1
21aseptic meningitis10.1
22rift valley fever10.1
23vasculitis10.1
24malaria10.0
25cerebellar ataxia10.0
26choroiditis10.0
27retinal vasculitis10.0
28crimean-congo hemorrhagic fever10.0
29quadriplegia10.0
30spinal cord disease10.0
31kidney disease10.0
32influenza10.0
33measles10.0
34hemorrhagic fever10.0
35ataxia10.0
36myoclonus10.0
37gonococcal keratitis10.0CCR5, OAS1, RSAD2
38erythema multiforme9.9CCR5, CD209, OAS1, TLR3
39inner ear disease9.9CD209, CLEC4M, IRF3, MX1
40neuroblastoma9.9
41acute lymphocytic leukemia9.9
42hepatitis9.9
43leukemia9.9
44myasthenia gravis9.9
45chikungunya9.9
46exanthem9.9
47paralytic poliomyelitis9.9
48stuttering9.9
49purpura fulminans9.9
50sensorineural hearing loss9.9

Graphical network of the top 20 diseases related to West Nile Virus:



Diseases related to west nile virus

Symptoms for West Nile Virus

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Clinical features from OMIM:

610379

UMLS symptoms related to West Nile Virus:


back pain, headache, pain, pruritus, sciatica, seizures, syncope, tremor, chronic pain, vertigo/dizziness, sleeplessness

Drugs & Therapeutics for West Nile Virus

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Drugs for West Nile Virus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
OseltamivirPhase 395204255-11-8, 196618-13-065028
Synonyms:
(-)-oseltamivir
(3R,4R,5S)-4-Acetylamino-5-amino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid
(3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylic acid
(−)-oseltamivir
196618-13-0
204255-11-8
4-Acetylamino-5-amino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid
AC1L22FK
AC1Q63H0
Agucort
Agucort (TN)
BIDD:GT0426
BRD-K76011241-045-01-5
C08092
CHEBI:7798
CHEMBL1229
CID65028
D08306
DB00198
Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate
Ethyl (5S,3R,4R)-4-(acetylamino)-5-amino-3-(ethylpropoxy)cyclohex-1-enecarboxylate
FT-0082384
 
GS 4104
GS-4104
GS4104
HMS2090C11
HSDB 7433
LS-57422
MolPort-005-933-026
NCGC00178698-01
Oseltamivir
Oseltamivir (INN)
Oseltamivir [INN:BAN]
Oseltamivir phosphate
Oseltamivirum
Ro-64-0796
Ro-640796
Tamiflu (*Phosphate salt 1:1*)
Tamiflu-Free
Tamvir
UNII-20O93L6F9H
ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate
oseltamivir
oseltamivirum
oséltamivir
2
NitazoxanidePhase 34555981-09-441684
Synonyms:
(2-((5-Nitro-2-thiazolyl)carbamoyl)phenyl)acetat
2-(Acetolyloxy)-N-(5-nitro-2-thiazolyl)benzamide
2-Acetyloxy-N-[(5-nitro-2-thiazolyl)]benzamide
2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate
55981-09-4
AC-1302
AC1L26A1
AC1Q5NVY
AZT + Nitazoxanide
Adrovet
Alinia
Alinia (TN)
BRN 1225475
C12H9N3O5S
CHEMBL1401
CID41684
CPD000466367
Colufase
Cryptaz
D02486
DB00507
Daxon
Daxon, Dexidex, Kidonax, Pacovanton, Paramix, Nitax, Zox, Nitazoxanide
EINECS 259-931-8
FT-0082459
HMS2051L04
Heliton
I14-6011
LS-144176
MLS000759492
MLS001424074
MolPort-002-042-244
N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester)
 
N-(5-Nitrothiazol-2-yl)salicylamide acetate ester
NCGC00090774-01
NCI60_034935
NCIMech_000843
NITAZOXANIDE
NSC 697855
NSC697855
Nitaxozanid
Nitaxozanide
Nitazoxanid
Nitazoxanida
Nitazoxanida [INN-Spanish]
Nitazoxanide (USAN/INN)
Nitazoxanide [USAN:INN]
Nitazoxanidum
Nitazoxanidum [INN-Latin]
Nodik
Omniparax
Oprea1_263587
Phavic-1
S1627_Selleck
SAM001246708
SBB068315
SMR000466367
STK395664
Salicylamide, N-(5-nitro-2-thiazolyl)- acetate (ester)
Salicylamide, N-(5-nitro-2-thiazolyl)-, acetate (ester)
Taenitaz
Tizoxanide Glucuronide
Tizoxanide glucuronide
UNII-SOA12P041N
ZINC03956788
[2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl] acetate
azt+ nitazoxanide
o-(N-(5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate
3
lactitolPhase 3325585-86-43871
Synonyms:
4-O-b-D-Galactopyranosyl-D-glucitol, 9CI
E966
Emportal
 
Floralac
Importal
Oponaf
Portolac
4
PaclitaxelPhase 2269133069-62-436314
Synonyms:
(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester
12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
157069-30-2
33069-62-4
5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.
7-Epi-Paclitaxel
7-Epi-Taxol
7-Epipaclitaxel
7-Epitaxol
7-epi-Paclitaxel
7-epi-Taxol
AB00513812
ABI 007
ABI-007
ABI007
AC-675
AC1L1IOG
AC1L1VJI
AC1L9AVF
ACon1_002231
ANX-513
Abraxane
Abraxane (TN)
Abraxane I.V. Suspension
Abraxis BioScience brand of albumin-bound paclitaxel
Ambotz33069-62-4
Anzatax
Asotax
BIDD:PXR0046
BMS 181339-01
BMS-181339
BMS-181339-01
BPBio1_000320
BRD-A23723433-001-01-2
BRD-A28746609-001-04-0
BRD-K62008436-001-03-1
BSPBio_000290
BSPBio_001152
BSPBio_002614
Bio-0076
Bio1_000362
Bio1_000851
Bio1_001340
Bio2_000416
Bio2_000896
Bristaxol
C07394
C466458
C47H51NO14
CCRIS 8143
CHEBI:103439
CHEBI:45863
CHEMBL100910
CHEMBL418410
CHEMBL48
CID36314
CID441276
CID4666
CID6713921
CID6915727
CPD-8718
Capxol
D00491
DB01229
DHP-107
DHP-208
DRG-0190
DTS-301
DivK1c_000441
EU-0101201
Ebetaxel
EmPAC
Epitaxol
Genaxol
Genetaxyl
Genexol
Genexol-PM
HMS1362J13
HMS1568O12
HMS1792J13
HMS1922K08
HMS1990J13
HMS2090D07
HMS2093K15
HMS501G03
HSDB 6839
I06-0014
IDI1_000441
IDI1_002171
Intaxel
KBio1_000441
KBio2_000492
KBio2_002016
KBio2_002509
KBio2_003060
KBio2_004584
KBio2_005077
KBio2_005628
KBio2_007152
KBio2_007645
KBio3_000903
KBio3_000904
KBio3_001834
KBio3_002987
KBioGR_000492
KBioGR_001893
 
KBioGR_002509
KBioSS_000492
KBioSS_002016
KBioSS_002517
LMPR0104390001
LS-31070
LipoPac
Lopac0_001201
MBT 0206
MEGxp0_001940
MLS000863266
MLS001077297
MLS002154218
MLS002172439
MLS002695976
MPI-5018
Micellar Paclitaxel
Mitotax
MolPort-001-742-627
MolPort-003-665-783
MolPort-003-932-365
NCGC00024995-02
NCGC00024995-03
NCGC00024995-04
NCGC00024995-05
NCGC00024995-06
NCGC00024995-07
NCGC00164367-01
NCGC00164367-02
NCGC00164367-03
NCI60_000601
NINDS_000441
NK 105
NP-010981
NSC 125973
NSC-125973
NSC125973
NSC358882
Nanotaxel
Neuro_000060
Nova-12005
OAS-PAC-100
OncoGel
Onxal
Onxol
Onxol, Taxol, Nov-Onxol, Paclitaxel
P1632
Paclical
Pacligel
Paclitaxel
Paclitaxel (JAN/USP)
Paclitaxel (JAN/USP/INN)
Paclitaxel (Taxol)
Paclitaxel [USAN:INN:BAN]
Paxceed
Paxene
Paxoral
Plaxicel
Praxel
Prestwick0_000155
Prestwick1_000155
Prestwick2_000155
Prestwick3_000155
Probes2_000350
QW 8184
S-8184 Paclitaxel Injectable Emulsion
S1150_Selleck
SDCCGMLS-0066823.P001
SDP-013
SMP1_000228
SMR000394086
SMR000857385
SPBio_000943
SPBio_002229
SPECTRUM1503908
ST50306996
Spectrum2_000872
Spectrum3_001057
Spectrum4_001197
Spectrum5_001491
Spectrum_001536
T 7402
T1912_SIGMA
T7191_SIGMA
T7402_SIGMA
TA1
TAXOL (TN)
TAXOL, 10-EPI,
TXL
TaxAlbin
Taxol
Taxol A
Taxol Konzentrat
Taxol.RTM. (Registered Trademark)
UNII-P88XT4IS4D
UPCMLD-DP108:001
UPCMLD-DP108:002
Vascular Wrap
Xorane
Yewtaxan
abi-007
albumin-bound paclitaxel
cMAP_000068
nab-paclitaxel
nchembio.188-comp1
nchembio.2007.34-comp9
nchembio.215-comp9
nchembio853-comp6
paclitaxel
weekly paclitaxel
5
CarboplatinPhase 2194241575-94-410339178, 498142, 38904
Synonyms:
(SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum
/h1-3H2,(H,7,8)(H,9,10)
/q
1,1-Cyclobutanedicarboxylate diammine platinum (II)
1,1-Cyclobutanedicarboxylate diammine platinum(II)
2*-1
2*1H2
41575-94-4
70903-55-8
AC-1457
AC1L8I6U
Ambap41575-94-4
BSPBio_003145
C 2538
C2043
C2538_SIGMA
C6H10N2O4Pt
CBDCA
CCRIS 3404
CHEBI:31355
CHEMBL1351
CHEMBL288376
CID10339178
CID2567
CID38904
CID426756
CID498142
CID5352133
CID6398587
CID6603770
Carbopaltin
Carboplatin
Carboplatin (JAN/USP/INN)
Carboplatin (USAN)
Carboplatin [USAN:INN:BAN:JAN]
Carboplatine
Carboplatine [French]
Carboplatino
Carboplatino [Spanish]
Carboplatinum
Carboplatinum [Latin]
Cbdca
Cyclobutane-1,1-dicarboxylate
D01363
DB00958
Diammine(1,1-cyclobutanedicarboxylato)platinum (II)
Diammine(cyclobutane-1,1-dicarboxylato(2-)-O,O')platinum
Diammine-1,1-cyclobutane dicarboxylate platinum II
DivK1c_000892
EINECS 255-446-0
EU-0100230
Ercar
HMS1921J16
HMS2090M05
HMS2092B22
HMS502M14
HSDB 6957
I14-2390
IDI1_000892
IUPAC: Azane
InChI=1/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6
 
JM 8
JM-8
KBio1_000892
KBio2_002009
KBio2_004577
KBio2_007145
KBio3_002645
KBioGR_000713
KBioSS_002009
LS-117689
Lopac-C-2538
Lopac0_000230
MolPort-003-665-501
MolPort-003-845-609
NCGC00015223-01
NCGC00093695-01
NCGC00094961-01
NCGC00094961-02
NCGC00094961-03
NCGC00162099-01
NCGC00162099-02
NCGC00167800-01
NCGC00178242-01
NINDS_000892
NSC 201345
NSC 241240
NSC-241240
NSC201345
NSC241240
Paraplatin
Paraplatin (TN)
Paraplatin, Carboplatin
Paraplatin-AQ
Platinum(+2) Cation
Platinum(II), (1, 1-cyclobutanedicar
Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2)
Platinum, {diammine[1,1-cyclobut
S1215_Selleck
SPBio_000716
SPECTRUM1502106
Spectrum2_000898
Spectrum3_001503
Spectrum4_000337
Spectrum5_001094
Spectrum_001529
UNII-BG3F62OND5
azanide
carboplatin
cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(ii)
cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II)
cis-Diammine(1,1-cyclobutanedicarboxylato) platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diammine(cyclobutanedicarboxylato)platinum II
cyclobutane-1,1-dicarboxylic acid
diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum
nchembio.573-comp10
nchembio773-comp2
nchembio873-comp3
platinum(2+)
6
RibavirinPhase 296836791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin
7
GlycineNutraceuticalPhase 1, Phase 219856-40-6750
Synonyms:
(1-13c)glycinato
(15N)Glycine
15527_RIEDEL
15527_SIAL
15743-44-9 (mono-potassium salt)
17829-66-2 (cobalt salt)
18875-39-3
2,2-dialkylglycines
2-Aminoacetate
2-Aminoacetic acid
2311-65-1
25718-94-9
29728-27-6 (monoammonium salt)
32817-15-5 (copper salt)
33226_RIEDEL
33226_SIAL
33242-26-1 (calcium salt)
35947-07-0 (calcium salt (2:1))
410225_SIAL
50046_FLUKA
50046_SIGMA
513-29-1 (sulfate (3:1))
52955-63-2
56-40-6
57678-19-0
6000-43-7 (hydrochloride)
6000-44-8 (mono-hydrochloride salt)
63183-41-5 (hydrochloride hydrogen carbonate)
71295-98-2 (phosphate (1:1))
7490-95-1 (hydrochloride (2:1)
7490-95-1 (hydrochloride (2:1))
7575-55-5
848646-45-7
87867-94-5
AB-131/40217813
AB1002628
AC1L19XW
AC1Q28JW
AC1Q53O0
AI3-04085
AKOS000119626
AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER
AR-1A0345
AR-1A0532
Acide aminoacetique
Acide aminoacetique [INN-French]
Acido aminoacetico
Acido aminoacetico [INN-Spanish]
Acidum aminoaceticum
Acidum aminoaceticum [INN-Latin]
Aciport
Amino-Acetate
Amino-Acetic acid
Aminoacetate
Aminoacetic acid
Aminoazijnzuur
Aminoessigsaeure
Aminoethanoate
Aminoethanoic acid
Amitone
B72BA06C-60E9-4A83-A24A-A2D7F465BB65
BPBio1_001222
Biomol-NT_000195
C00037
CCRIS 5915
CHEBI:15428
CHEBI:15705
CHEBI:16228
CHEMBL773
CID750
CPD-8569
Corilin
D00011
DB00145
EINECS 200-272-2
 
FEMA No. 3287
FT-0083159
G
G0099
G0317
G5417_SIGMA
G5523_SIGMA
G7126_SIGMA
G7403_SIGMA
G8790_SIGMA
G8898_SIGMA
GLY (IUPAC abbrev)
GLYCINE 1.5% IN PLASTIC CONTAINER
GLYCINE, ACS
Glicina
Glicina [INN-Spanish]
Glicoamin
Gly
Glycin
Glycine
Glycine (JP15/USP)
Glycine [INN]
Glycine iron sulphate (1:1)
Glycine, homopolymer (VAN)
Glycine, labeled with carbon-14
Glycine, non-medical
Glycine-UL-14C hydrochloride
Glycinum
Glycinum [INN-Latin]
Glycocoll
Glycolixir
Glycosthene
Glykokoll
Glyzin
Gyn-Hydralin
Gyn-hydralin
H-Gly-OH
H2N-CH2-COOH
HSDB 495
Hampshire glycine
Hgly
InChI=1/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5
KST-1A2919
KST-1A8102
L-Glycine
L-alpha-amino acids
L001246
LS-218
Leimzucker
MolPort-000-871-607
NCGC00024503-01
NCGC00024503-02
NChemBio.2007.13-comp1
NSC 25936
NSC25936
P8791_SIGMA
Padil
Polyglycine II
S04-0135
Sucre de gelatine
Tocris-0219
UNII-TE7660XO1C
W328707_ALDRICH
WLN: Z1VQ
aminoacetic acid
an alpha amino acid ester
bmse000089
gly
glycine
nchem.554-comp2
nchembio.121-comp9
nchembio.145-comp33
nchembio.198-comp12
nchembio.265-comp9
nchembio.266-comp30
polyglycine
8
Aluminum hydroxidePhase 119421645-51-2
Synonyms:
Al(OH)3
Aluminium hydroxide
Aluminium hydroxide gel, dried
 
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried
Dried aluminium hydroxide
Dried aluminum hydroxide gel
9
Natalizumab96189261-10-7
Synonyms:
189261-10-7
Anti-VLA4
Anti-alpha4 integrin
 
D06886
Natalizumab
Natalizumab (INN)
Tysabri
Tysabri (TN)

Interventional clinical trials:

(show all 38)
idNameStatusNCT IDPhase
1Organ Transplant Infection Prevention and Detection ProjectCompletedNCT00177801Phase 4
2Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy InfantsCompletedNCT00806195Phase 3
3A Study to Evaluate the Safety and Immunogenicity of 4 Doses of MenACWY Conjugate Vaccine, Administered Concomitantly With Routine Vaccines, Among Infants Aged 2 MonthsCompletedNCT01000311Phase 3
4Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' Measles, Mumps and Rubella (MMR) Vaccine (209762) Compared to Merck & Co., Inc.'s MMR Vaccine in Healthy Children 12 to 15 Months of AgeCompletedNCT02184572Phase 3
5A Study to Evaluate the Immunogenicity of Quadrivalent Live Attenuated Influenza Vaccine (LAIV) in ChildrenCompletedNCT01091246Phase 3
6Immunogenicity and Safety of Pediatric Vaccines When Administered With Menactra® in Healthy ToddlersCompletedNCT00422292Phase 3
7Evaluation of Safety and Immunogenicity of Co-administering HPV Vaccine With Other Vaccines in Healthy Female SubjectsCompletedNCT00369824Phase 3
8Safety and Efficacy Study of Nitazoxanide in the Treatment of Acute Uncomplicated InfluenzaCompletedNCT01610245Phase 3
9Omr-IgG-am(Trademark) for Treating Patients With or at High Risk for West Nile Virus DiseaseCompletedNCT00069316Phase 2
10IVIG - West Nile Encephalitis: Safety and EfficacyCompletedNCT00068055Phase 1, Phase 2
11Safety and Immunogenicity Study of ChimeriVax West Nile Vaccine in Healthy AdultsCompletedNCT00746798Phase 2
12Safety and Immunogenicity of ChimeriVax-WN02 West Nile Vaccine in Healthy AdultsCompletedNCT00442169Phase 2
13Safety and Efficacy Study of Intravenous Immunoglobulin to Treat Japanese EncephalitisCompletedNCT01856205Phase 2
14Immunogenicity and Safety of GlaxoSmithKline Biologicals' MMRV Vaccine vs. ProQuad® in Children 12-14 Months of AgeCompletedNCT00578175Phase 2
15Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Larynx or Oropharynx CancerCompletedNCT00014118Phase 2
16Treatment of Japanese EncephalitisRecruitingNCT00216268Phase 2
17Treatment of West Nile Virus With MGAWN1TerminatedNCT00927953Phase 2
18Phase I Study of West Nile Virus VaccineCompletedNCT00300417Phase 1
19Vaccine to Prevent West Nile Virus DiseaseCompletedNCT00106769Phase 1
20A Trial to Evaluate the Safety of a Single Intravenous Infusion of MGAWN1 in Healthy AdultsCompletedNCT00515385Phase 1
21Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4-3'delta30) in Healthy AdultsCompletedNCT00094718Phase 1
22Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020CompletedNCT00387283Phase 1
23Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4delta30) in Healthy AdultsCompletedNCT00537147Phase 1
24Safety Study of HBV-002 West Nile Vaccine in Healthy AdultsCompletedNCT00707642Phase 1
25Pharmacokinetic Study of a Single Dose of AVI-4065 in Cerebral Spinal FluidCompletedNCT00381433Phase 1
26Phase 1 Trial of Inactivated West Nile Virus VaccineActive, not recruitingNCT02337868Phase 1
27Evaluating the Safety and Immunogenicity of a Live Attenuated West Nile Virus Vaccine for West Nile Encephalitis in Adults 50 to 65 Years of AgeActive, not recruitingNCT02186626Phase 1
28An Exploratory Study of AVI-4020 in Patients With Possible Acute Neuroinvasive West Nile Virus (WNV) DiseaseTerminatedNCT00091845Phase 1
29West Nile Virus Natural HistoryCompletedNCT00138463
30Natural History of West Nile Virus InfectionCompletedNCT00069303
31Retrovirus Epidemiology Donor Study-II (REDS-II)CompletedNCT00097006
32Surveillance of Summer Febrile Syndromes of Viral Origin in South of FranceCompletedNCT00842166
33VRC 300: Screening of Healthy Volunteers for Clinical Trials of Investigational Vaccines to Prevent Infectious DiseasesCompletedNCT00068926
34JC Virus Antibody Study of Participants With Relapsing Forms of MS Receiving Treatment With NatalizumabCompletedNCT01070836
35An Observational Study to Assess Respiratory Syncytial Virus (RSV) Respiratory Events Among Premature InfantsCompletedNCT00983606
36Prevalence of Antibodies to Selected Porcine Viruses in Patients With Cystic Fibrosis Receiving Porcine-derived Pancreatic Enzyme Replacement TherapyCompletedNCT01858519
37Cohort of Patients Infected by an ArbovirusRecruitingNCT01099852
38Expanded Access to MGAWN1 in Subjects With Suspected West Nile Neuroinvasive Disease; Suspected West Nile Virus Infection; or Substantial Accidental ExposureNo longer availableNCT01206504

Search NIH Clinical Center for West Nile Virus

Genetic Tests for West Nile Virus

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Genetic tests related to West Nile Virus:

id Genetic test Affiliating Genes
1 West Nile Virus, Susceptibility to25

Anatomical Context for West Nile Virus

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MalaCards organs/tissues related to West Nile Virus:

34
Brain, Testes, Skin, Spinal cord, T cells, B cells, Kidney

Animal Models for West Nile Virus or affiliated genes

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MGI Mouse Phenotypes related to West Nile Virus:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.7CCR5, DDX58, ITGAV, ITGB3, STAT1, TLR3
2MP:00053977.4CCR5, CLEC4M, DDX58, HELLS, ITGAV, ITGB3
3MP:00053877.0CCR5, CLEC4M, DDX58, HELLS, IFITM3, IRF3

Publications for West Nile Virus

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Articles related to West Nile Virus:

(show top 50)    (show all 741)
idTitleAuthorsYear
1
Generating West Nile Virus from an Infectious Clone. (27188548)
2016
2
Bibliometric assessment of scientific production of literature of West Nile Virus. (27659112)
2016
3
Implementation of a sampling strategy to detect West Nile virus in oral and cloacal samples in live song birds. (25863262)
2015
4
Allele-specific qRT-PCR demonstrates superior detection of single nucleotide polymorphisms as genetic markers for West Nile virus compared to LuminexAr and quantitative sequencing. (24121135)
2014
5
Host group formation decreases exposure to vector-borne disease: a field experiment in a 'hotspot' of West Nile virus transmission. (25339722)
2014
6
Molecular detection and isolation of West Nile virus from a human case in northern Greece, 2013. (25356324)
2013
7
Small molecule inhibitors of West Nile virus. (23636899)
2013
8
Pathogenesis of West Nile virus lineage 1 and 2 in experimentally infected large falcons. (22909991)
2013
9
West Nile virus infection. (23897943)
2013
10
Arenavirus and West Nile virus in solid organ transplantation. (23465029)
2013
11
West Nile virus drug discovery. (24300672)
2013
12
West Nile Virus Infection in the Immunocompromised Patient. (24234656)
2013
13
Integrins modulate the infection efficiency of West Nile virus into cells. (23658209)
2013
14
Serologic survey of West Nile virus in horses from Central-West, Northeast and Southeast Brazil. (24037110)
2013
15
West Nile virus genome with glycosylated envelope protein and deletion of alpha helices 1, 2, and 4 in the capsid protein is noninfectious and efficiently secretes subviral particles. (24049184)
2013
16
Development and characterization of new peptidomimetic inhibitors of the West Nile virus NS2B-NS3 protease. (23307694)
2013
17
Regional and seasonal response of a West Nile virus vector to climate change. (24019459)
2013
18
Brachial plexitis preceding encephalomyelitis in a patient with West Nile virus infection. (24311412)
2013
19
Development and evaluation of NS1 specific monoclonal antibody based antigen capture ELISA and its implications in clinical diagnosis of West Nile virus infection. (24095027)
2013
20
Neuroinvasive West Nile virus disease in Canada. The Saskatchewan experience. (23786744)
2013
21
The evolution of virulence of West Nile virus in a mosquito vector: implications for arbovirus adaptation and evolution. (23514328)
2013
22
Role of natural killer and Gamma-delta T cells in West Nile virus infection. (24061543)
2013
23
West Nile Virus equine serosurvey in the Czech and Slovak republics. (23919605)
2013
24
West Nile alternative open reading frame (N-NS4B/WARF4) is produced in infected West Nile Virus (WNV) cells and induces humoral response in WNV infected individuals. (23173701)
2012
25
In vitro and in vivo activity of AS101 against West Nile virus (WNV). (22445690)
2012
26
Structural gene (prME) chimeras of St Louis encephalitis virus and West Nile virus exhibit altered in vitro cytopathic and growth phenotypes. (21940408)
2012
27
Impaired virus clearance, compromised immune response and increased mortality in type 2 diabetic mice infected with West Nile virus. (22953001)
2012
28
West Nile virus neurologic disease in humans, South Africa, September 2008-may 2009. (23171668)
2012
29
Quantification of intrahost bottlenecks of West Nile virus in Culex pipiens mosquitoes using an artificial mutant swarm. (22326536)
2012
30
West Nile virus (WNV) replication is independent of autophagy in mammalian cells. (23029249)
2012
31
Glial S100B is elevated in serum across the spectrum of West Nile virus infection. (22581535)
2012
32
Novel West Nile virus lineage 1a full genome sequences from human cases of infection in north-eastern Italy, 2011. (23004685)
2012
33
West Nile Virus workshop: scientific considerations for tissue donors. (22134724)
2012
34
Secreted Vago restricts West Nile virus infection in Culex mosquito cells by activating the Jak-STAT pathway. (23027947)
2012
35
West Nile virus transmission through organ transplantation in north-eastern Italy: a case report and implications for pre-procurement screening. (22544764)
2012
36
Detection of West Nile virus RNA (lineages 1 and 2) in an external quality assessment programme for laboratories screening blood and blood components for West Nile virus by nucleic acid amplification testing. (23117401)
2012
37
Reactivation West Nile virus infection-related chorioretinitis. (22784261)
2012
38
The costs of infection and resistance as determinants of West Nile virus susceptibility in Culex mosquitoes. (21975028)
2011
39
Host genetic risk factors for West Nile virus infection and disease progression. (21935451)
2011
40
West Nile virus experimental evolution in vivo and the trade-off hypothesis. (22102808)
2011
41
West Nile virus infection does not induce PKR activation in rodent cells. (21982595)
2011
42
Spatio-temporal patterns of distribution of West Nile virus vectors in eastern Piedmont Region, Italy. (22152822)
2011
43
Simultaneous detection and differentiation of dengue virus serotypes 1-4, Japanese encephalitis virus, and West Nile virus by a combined reverse-transcription loop-mediated isothermal amplification assay. (21777455)
2011
44
Persistent West Nile virus transmission and the apparent displacement St. Louis encephalitis virus in southeastern California, 2003-2006. (18533445)
2008
45
West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling. (16501100)
2006
46
West Nile virus encephalitis with myositis and orchitis. (14991545)
2004
47
The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World. (15550172)
2004
48
West Nile virus and the safety of plasma derivatives: verification of high safety margins, and the validity of predictions based on model virus data. (12869106)
2003
49
Immunoassay targeting nonstructural protein 5 to differentiate West Nile virus infection from dengue and St. Louis encephalitis virus infections and from flavivirus vaccination. (12958248)
2003
50
Isolation of eastern equine encephalitis virus and West Nile virus from crows during increased arbovirus surveillance in Connecticut, 2000. (12164299)
2002

Variations for West Nile Virus

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Expression for genes affiliated with West Nile Virus

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Search GEO for disease gene expression data for West Nile Virus.

Pathways for genes affiliated with West Nile Virus

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Pathways related to West Nile Virus according to GeneCards Suite gene sharing:

(show all 16)
idSuper pathwaysScoreTop Affiliating Genes
110.0ITGAV, ITGB3
29.8CD209, ITGAV, ITGB3
39.8ITGAV, ITGB3, TLR3
49.7ITGAV, ITGB3, STAT1
59.6CD209, CLEC4M, ITGAV, ITGB3
6
Show member pathways
9.1DDX58, IRF3, MX1, OAS1, STAT1
7
Show member pathways
8.9DDX58, IFNA1, IRF3, TLR3
88.9CD209, CLEC4M, IFNA1, STAT1
9
Show member pathways
8.6CD209, IFNA1, IRF3, STAT1, TLR3
10
Show member pathways
8.5DDX58, IFNA1, IRF3, STAT1, TLR3
117.9DDX58, IFNA1, IRF3, OAS1, RNASEL, STAT1
127.6DDX58, IFNA1, IRF3, OAS1, RSAD2, STAT1
13
Show member pathways
6.5CD209, CLEC4M, DDX58, IFNA1, IRF3, MX1
14
Show member pathways
6.3IFITM1, IFITM2, IFITM3, IFNA1, IRF3, MX1
15
Show member pathways
6.1DDX58, IFITM1, IFITM2, IFITM3, IFNA1, IRF3
16
Show member pathways
4.8CD209, DDX58, IFITM1, IFITM2, IFITM3, IFNA1

GO Terms for genes affiliated with West Nile Virus

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Cellular components related to West Nile Virus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1integrin alphav-beta3 complexGO:003468310.7ITGAV, ITGB3
2alphav-beta3 integrin-IGF-1-IGF1R complexGO:003586710.7ITGAV, ITGB3
3filopodium membraneGO:003152710.2ITGAV, ITGB3
4lamellipodium membraneGO:003125810.1ITGAV, ITGB3
5ruffle membraneGO:00325879.9DDX58, ITGAV, ITGB3
6cell surfaceGO:00099869.4CCR5, CD209, ITGAV, ITGB3, TLR3

Biological processes related to West Nile Virus according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of lipoprotein metabolic processGO:005074810.7ITGAV, ITGB3
2negative regulation of low-density lipoprotein particle receptor biosynthetic processGO:004571510.7ITGAV, ITGB3
3negative regulation of lipid transportGO:003236910.7ITGAV, ITGB3
4apolipoprotein A-I-mediated signaling pathwayGO:003802710.7ITGAV, ITGB3
5cellular response to dsRNAGO:007135910.6IRF3, TLR3
6peptide antigen transportGO:004696810.6CD209, CLEC4M
7cell-cell recognitionGO:000998810.6CD209, CLEC4M
8virion attachment to host cellGO:001906210.6CD209, CLEC4M
9cell-substrate adhesionGO:003158910.6ITGAV, ITGB3
10negative regulation of macrophage derived foam cell differentiationGO:001074510.6ITGAV, ITGB3
11negative regulation of lipid storageGO:001088810.6ITGAV, ITGB3
12modulation by virus of host morphology or physiologyGO:001904810.5CD209, CLEC4M
13viral genome replicationGO:001907910.3CD209, CLEC4M
14positive regulation of interferon-alpha productionGO:003272710.2DDX58, IRF3
15cellular response to interferon-betaGO:003545810.2STAT1, TLR3
16detection of virusGO:000959710.2DDX58, TLR3
17interferon-gamma-mediated signaling pathwayGO:006033310.2IRF3, OAS1, STAT1
18negative regulation of viral entry into host cellGO:00465979.9IFITM1, IFITM2, IFITM3
19response to interferon-alphaGO:00354559.9IFITM1, IFITM2, IFITM3
20positive regulation of interferon-beta productionGO:00327289.9DDX58, IRF3, TLR3
21viral entry into host cellGO:00467189.6CD209, CLEC4M, ITGAV, ITGB3
22response to interferon-betaGO:00354569.6IFITM1, IFITM2, IFITM3, STAT1
23response to interferon-gammaGO:00343419.4IFITM1, IFITM2, IFITM3
24response to exogenous dsRNAGO:00433308.8DDX58, IFNA1, IRF3, TLR3
25innate immune responseGO:00450878.5CD209, CLEC4M, DDX58, IFNA1, MX1, TLR3
26negative regulation of viral genome replicationGO:00450718.3IFITM1, IFITM2, IFITM3, MX1, OAS1, RNASEL
27response to virusGO:00096157.6DDX58, IFITM1, IFITM2, IFITM3, MX1, OAS1
28type I interferon signaling pathwayGO:00603376.9IFITM1, IFITM2, IFITM3, IFNA1, IRF3, MX1
29defense response to virusGO:00516075.7IFITM1, IFITM2, IFITM3, IFNA1, IRF3, MX1

Molecular functions related to West Nile Virus according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1neuregulin bindingGO:003813210.6ITGAV, ITGB3
2insulin-like growth factor I bindingGO:003199410.6ITGAV, ITGB3
3virion bindingGO:004679010.4CD209, CLEC4M
4C-X3-C chemokine bindingGO:001996010.4ITGAV, ITGB3
5coreceptor activityGO:001502610.1CCR5, ITGAV, ITGB3
6mannose bindingGO:000553710.0CD209, CLEC4M
7double-stranded RNA bindingGO:00037259.6DDX58, OAS1, TLR3
8virus receptor activityGO:00016189.1CCR5, CD209, CLEC4M, ITGAV, ITGB3

Sources for West Nile Virus

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet