MCID: WHT017
MIFTS: 30

Wheat Allergy malady

Categories: Immune diseases

Aliases & Classifications for Wheat Allergy

Aliases & Descriptions for Wheat Allergy:

Name: Wheat Allergy 12 14
Wheat Hypersensitivity 42 69
Wheat Allergic Reaction 12
Allergy to Wheat 12
Allergy Wheat 52

Classifications:



External Ids:

Disease Ontology 12 DOID:3660
MeSH 42 D021182
SNOMED-CT 64 420174000
UMLS 69 C0949570

Summaries for Wheat Allergy

MalaCards based summary : Wheat Allergy, also known as wheat hypersensitivity, is related to food allergy and granulomatous angiitis. An important gene associated with Wheat Allergy is SCP2 (Sterol Carrier Protein 2), and among its related pathways/superpathways is PPAR signaling pathway. The drugs Budesonide and Montelukast have been mentioned in the context of this disorder. Related phenotype is homeostasis/metabolism.

Wikipedia : 71 Wheat allergy is an allergy which typically presents itself as a food allergy, but can also be a contact... more...

Related Diseases for Wheat Allergy

Graphical network of the top 20 diseases related to Wheat Allergy:



Diseases related to Wheat Allergy

Symptoms & Phenotypes for Wheat Allergy

MGI Mouse Phenotypes related to Wheat Allergy:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.02 CD79A FABP2 SCP2 TGM2 TOR1A

Drugs & Therapeutics for Wheat Allergy

Drugs for Wheat Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 184)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Budesonide Approved Phase 4,Phase 3 51333-22-3 63006 5281004
2
Montelukast Approved Phase 4 158966-92-8 5281040
3 Anti-Allergic Agents Phase 4,Phase 3,Phase 2
4 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2
5 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
6 Autonomic Agents Phase 4,Phase 3,Phase 2
7 Bronchodilator Agents Phase 4,Phase 3,Phase 2
8 Dermatologic Agents Phase 4,Phase 3,Phase 2
9
Fluticasone Phase 4,Phase 3,Phase 2 90566-53-3, 80474-14-2 62924 22833648
10 glucocorticoids Phase 4,Phase 3,Phase 2
11 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
12 Hormones Phase 4,Phase 3,Phase 2,Phase 1
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
14 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
15 Respiratory System Agents Phase 4,Phase 3,Phase 2
16 Adrenergic Agents Phase 4,Phase 3,Phase 2
17 Adrenergic Agonists Phase 4,Phase 3,Phase 2
18 Adrenergic beta-2 Receptor Agonists Phase 4,Phase 2,Phase 3
19 Adrenergic beta-Agonists Phase 4,Phase 3,Phase 2
20 Albuterol Phase 4,Phase 2,Phase 3
21 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
22 Pharmaceutical Solutions Phase 4,Phase 3
23 Tocolytic Agents Phase 4,Phase 3,Phase 2
24 Fluticasone Propionate, Salmeterol Xinafoate Drug Combination Phase 4,Phase 3
25
Salmeterol xinafoate Phase 4,Phase 3 94749-08-3 56801
26 Leukotriene Antagonists Phase 4
27 Bromides Phase 4,Phase 2,Phase 3
28 Cholinergic Agents Phase 4,Phase 2,Phase 3
29 Cholinergic Antagonists Phase 4,Phase 2,Phase 3
30 Anticonvulsants Phase 4
31 Muscarinic Antagonists Phase 4
32 Olive Nutraceutical Phase 4
33 Soy Bean Nutraceutical Phase 4,Phase 2,Phase 3,Early Phase 1
34
Carmustine Approved Phase 3 154-93-8 2578
35
Epinephrine Approved, Vet_approved Phase 3 51-43-4 5816
36
Adalimumab Approved Phase 3 331731-18-1 16219006
37
Naproxen Approved, Vet_approved Phase 2, Phase 3 22204-53-1 1302 156391
38
Gemcitabine Approved Phase 3,Phase 2 95058-81-4 60750
39
Fluorouracil Approved Phase 3,Phase 2 51-21-8 3385
40
Cetuximab Approved Phase 3,Phase 2 205923-56-4 56842117 2333
41
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
42
Doxorubicin Approved, Investigational Phase 3 23214-92-8 31703
43
Olaparib Approved Phase 3 763113-22-0 23725625
44
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
45
Benzocaine Approved Phase 3 1994-09-7, 94-09-7 2337
46
Bicalutamide Approved Phase 3 90357-06-5 56069 2375
47
Leuprolide Approved, Investigational Phase 3 53714-56-0 3911 657181
48
Bevacizumab Approved, Investigational Phase 3 216974-75-3
49
Cisplatin Approved Phase 3 15663-27-1 84093 441203 2767
50
Succinylcholine Approved Phase 3 306-40-1 5314

Interventional clinical trials:

(show top 50) (show all 140)
id Name Status NCT ID Phase
1 Dietetic Versus Topical Steroids for Pediatric Eosinophilic Esophagitis Unknown status NCT01846962 Phase 4
2 Costs & Outcomes of Hospitalization/Treatment With Levalbuterol & Albuterol in Asthma or Chronic Obstructive Pulmonary Disease (COPD) Subjects Completed NCT00667797 Phase 4
3 A Clinical Study With Fluticasone Furoate Nasal Spray And Vehicle Placebo For The Treatment Of Perennial (Year-round) Allergic Rhinitis Completed NCT00682643 Phase 4
4 SAS115359: A 6-month Study to Assess the Safety and Benefit of Inhaled Fluticasone Propionate/Salmeterol Combination Compared With Inhaled Fluticasone Propionate in the Treatment of Adolescents and Adults (12 Years of Age and Older) With Asthma. Completed NCT01475721 Phase 4
5 GSK BHR Study (Sont - Second Study) Completed NCT01324362 Phase 4
6 GSK BHR Study (Sont) Completed NCT00920543 Phase 4
7 Study Of Patients With Allergic Rhinitis And Asthma Completed NCT00296530 Phase 4
8 Study Of Asthma And Genetics In Patients To Be Treated With Fluticasone Propionate/Salmeterol Or Salmeterol Xinafoate Completed NCT00102882 Phase 4
9 Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and Exacerbations in Moderate to Very Severe COPD Patients. Active, not recruiting NCT01966107 Phase 4
10 Phase III Cat-PAD Study Completed NCT01620762 Phase 3
11 S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma Completed NCT00017147 Phase 3
12 Epinephrine Inhalation Aerosol USP: For Evaluation Of Efficacy And Safety In Asthma Patients Completed NCT01357642 Phase 3
13 A Study of Lebrikizumab in Participants With Uncontrolled Asthma on Inhaled Corticosteroids and a Second Controller Medication Completed NCT01868061 Phase 3
14 26 Week Efficacy, Safety and Tolerability Study of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD) Completed NCT00463567 Phase 2, Phase 3
15 Long-term Safety and Tolerability Study of Adalimumab in Subjects With Crohn's Disease Completed NCT00195715 Phase 3
16 Evaluation of Tiotropium 2.5 and 5 mcg Once Daily Delivered Via the Respimat® Inhaler Compared to Placebo and Salmeterol HydroFluoroAlkane (HFA) Metered Dose Inhaler (MDI) (50 mcg Twice Daily) in Patient With Moderate Persistent Asthma I Completed NCT01172808 Phase 3
17 MGR001 / Advair Diskus Local Equivalence Study in Asthma Completed NCT02245672 Phase 3
18 A Safety and Efficacy Study of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Participants >=12 Years Old With Persistent Asthma Completed NCT02031640 Phase 3
19 An Efficacy and Safety Study of Fluticasone Furoate/Vilanterol (FF/VI) 200/25 Microgram (mcg) , FF/VI 100/25 mcg, and FF 100 mcg in Adults and Adolescents With Persistent Asthma. Completed NCT01686633 Phase 3
20 Study to Evaluate the Efficacy and Safety of Reslizumab Treatment in Patients With Moderate to Severe Asthma Completed NCT01508936 Phase 3
21 Safety Study in Adolescent and Adult Patients With Asthma Completed NCT01476904 Phase 3
22 A Two-week Study Assessing the Onset of Effect Questionnaire Administered Pre-dose Versus Post-dose in Adult Subjects Completed NCT00449501 Phase 3
23 Rates of Gastric Ulcer by Endoscopy in Knee Osteoarthritis Patients Receiving LT-NS001 Versus Naprosyn® Completed NCT01063920 Phase 2, Phase 3
24 SOFEED: Six Food vs. One Food Eosinophilic Esophagitis Diet Study Recruiting NCT02778867 Phase 2, Phase 3
25 Olaparib or Cediranib Maleate and Olaparib Compared With Standard Platinum-Based Chemotherapy in Treating Patients With Recurrent Platinum-Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Recruiting NCT02446600 Phase 3
26 Eosinophilic Esophagitis (EoE) Intervention Trial-Randomized 1 Food Elimination vs. 4 Food Elimination Diet Followed by Swallowed Glucocorticoids Recruiting NCT02610816 Phase 2, Phase 3
27 S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer Recruiting NCT01809691 Phase 3
28 Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer Recruiting NCT00565851 Phase 3
29 An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE) Recruiting NCT02736409 Phase 3
30 A Placebo- Controlled Study in Adolescents and Adults With Eosinophilic Esophagitis (EoE) Measuring Histologic Response and Determine if Reduction in Dysphagia is Achieved Recruiting NCT02605837 Phase 3
31 Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Active, not recruiting NCT00588770 Phase 3
32 Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With Stage III or Stage IV Head and Neck Cancer Active, not recruiting NCT00265941 Phase 3
33 A Safety Extension Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Asthmatic Adults and Adolescents on Inhaled Corticosteroid Plus LABA Active, not recruiting NCT02258542 Phase 3
34 GALLANT 5 Tesaglitazar Versus Metformin Terminated NCT00214591 Phase 3
35 A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standard of Care Alone in Adults and Adolescents Who Are Hospitalized Due to Influenza Terminated NCT00958776 Phase 3
36 Therapeutic Effect of Chinese Herbal Medicine on Food Allergy Unknown status NCT00602160 Phase 2
37 Combined Rg3-enriched Korean Red Ginseng and American Ginseng in the Management of Hypertension in Type 2 Diabetes Unknown status NCT01578837 Phase 1, Phase 2
38 Oral Immunotherapy for Wheat Allergy Completed NCT01980992 Phase 1, Phase 2
39 Inoculating Celiac Disease Patients With the Human Hookworm Necator Americanus: Evaluating Immunity and Gluten-sensitivity Completed NCT00671138 Phase 2
40 Evaluating the Effect of Fumaria Parviflora L. in Uremic Pruritus Completed NCT02671162 Phase 2
41 A Study of Amphotericin B in the Treatment of Fungal Infections of the Mouth in HIV-Infected Patients Who Have Not Had Success With Fluconazole Completed NCT00001065 Phase 2
42 A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDS Completed NCT00000975 Phase 2
43 Konjac-Glucomannan Fibre Blend and American Ginseng in Type 2 Diabetes Completed NCT02806349 Phase 2
44 Controlled Trial of Chinese Herbal Medicine to Treat Allergic Rhinitis Completed NCT02027194 Phase 1, Phase 2
45 Cetuximab in Treating Patients With Recurrent or Stage IIIB or Stage IV Lung Cancer Completed NCT00103207 Phase 2
46 Panitumumab, Chemotherapy, and External-Beam Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer That Cannot be Removed by Surgery Completed NCT00601627 Phase 2
47 A Study of ARRY-502 in Patients With Persistent Asthma Completed NCT01561690 Phase 2
48 Efficacy and Safety of 4 Weeks of Treatment With Inhaled BI 1744 CL in Patients With Asthma Completed NCT00467740 Phase 2
49 Combivent® CFC Metered Dose Inhaler (MDI) in Moderate to Severe Asthma Completed NCT00096616 Phase 2
50 Dose-Ranging Study in Patients With Chronic Obstructive Pulmonary Disease (COPD) Completed NCT00098228 Phase 2

Search NIH Clinical Center for Wheat Allergy

Cochrane evidence based reviews: wheat hypersensitivity

Genetic Tests for Wheat Allergy

Anatomical Context for Wheat Allergy

Publications for Wheat Allergy

Articles related to Wheat Allergy:

(show all 31)
id Title Authors Year
1
What Do We Know Now about IgE-Mediated Wheat Allergy in Children? ( 28054973 )
2017
2
THE COMPARISON OF EFFECTIVENESS OF SLOW SPECIFIC ORAL IMMUNOTHERAPY FOR WHEAT ALLERGY USING TWO DIFFERENT INTAKE FREQUENCY. ( 27616175 )
2016
3
INCIDENCE OF APNEA ATTACK AS ALLERGIC REACTION AFTER ORAL FOOD CHALLENGE IN PATIENT WITH IgE-MEDIATED WHEAT ALLERGY. ( 27616176 )
2016
4
Wheat allergy in celiac children. ( 26360318 )
2016
5
Very low prevalence of IgE mediated wheat allergy and high levels of cross-sensitisation between grass and wheat in a UK birth cohort. ( 27335632 )
2016
6
Wheat Allergy and Intolerence; Recent Updates and Perspectives. ( 24915366 )
2016
7
Age of Resolution from IgE-Mediated Wheat Allergy. ( 27543738 )
2016
8
Wheat allergy: diagnosis and management. ( 26889090 )
2016
9
Food IgG4 antibodies are elevated not only in children with wheat allergy but also in children with gastrointestinal diseases. ( 27004959 )
2016
10
Clinical presentation, allergens, and management of wheat allergy. ( 26800201 )
2016
11
Celiac Disease, Wheat Allergy, and Non-Celiac Gluten Sensitivity: What's the Difference? ( 27363231 )
2016
12
Better management of wheat allergy using a very low-dose food challenge: A retrospective study. ( 26666490 )
2016
13
Remission rate of patients with wheat allergy sensitized to hydrolyzed wheat protein in facial soap. ( 26666491 )
2016
14
Wheat allergy in a pediatric population from the Mediterranean area. ( 26177963 )
2015
15
IgE reactivity to carbohydrate moieties of glycoproteins in wheat allergy. ( 25976436 )
2015
16
Current trends and investigative developments in wheat allergy. ( 26288112 )
2015
17
Diagnosis of gluten related disorders: Celiac disease, wheat allergy and non-celiac gluten sensitivity. ( 26109797 )
2015
18
Wheat allergy in children evaluated with challenge and IgE antibodies to wheat components. ( 25601168 )
2015
19
Current Trends and Investigative Developments in Wheat Allergy. ( 26241163 )
2015
20
Eighteen cases of wheat allergy and wheat-dependent exercise-induced urticaria/anaphylaxis sensitized by hydrolyzed wheat protein in soap. ( 26096789 )
2015
21
The natural history of IgE mediated wheat allergy in children with dominant gastrointestinal symptoms. ( 24572171 )
2014
22
Oral immunotherapy in children with IgE-mediated wheat allergy: outcome and molecular changes. ( 25219106 )
2014
23
Wheat allergy in children - new tools for diagnostics. ( 25146380 )
2014
24
A new reliable method for detecting specific IgE antibodies in the patients with immediate type wheat allergy due to hydrolyzed wheat protein: correlation of its titer and clinical severity. ( 24759554 )
2014
25
A curious case of exercise-induced wheat allergy in adulthood. ( 24765886 )
2014
26
Epidemiological link between wheat allergy and exposure to hydrolyzed wheat protein in facial soap. ( 25040662 )
2014
27
Antigen-induced expression of CD203c on basophils predicts IgE-mediated wheat allergy. ( 19240377 )
2009
28
Wheat allergy. ( 19318930 )
2009
29
The natural history of wheat allergy. ( 19492663 )
2009
30
[Effect of hypoallergenic wheat (HAW-A1) on atopic dermatitis (AD) with wheat allergy, and its antigenic analysis using sera from patients with AD]. ( 8067902 )
1994
31
Masked type I wheat allergy. Relation to exercise-induced anaphylaxis. ( 3977357 )
1985

Variations for Wheat Allergy

Expression for Wheat Allergy

Search GEO for disease gene expression data for Wheat Allergy.

Pathways for Wheat Allergy

Pathways related to Wheat Allergy according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.48 FABP2 SCP2

GO Terms for Wheat Allergy

Biological processes related to Wheat Allergy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein homooligomerization GO:0051260 8.62 TGM2 TOR1A

Molecular functions related to Wheat Allergy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transferase activity, transferring acyl groups GO:0016746 8.62 SCP2 TGM2

Sources for Wheat Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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