Aliases & Classifications for Wheat Allergy

MalaCards integrated aliases for Wheat Allergy:

Name: Wheat Allergy 12 14
Wheat Hypersensitivity 41 69
Wheat Allergic Reaction 12
Allergy to Wheat 12
Allergy Wheat 51

Classifications:



External Ids:

Disease Ontology 12 DOID:3660
MeSH 41 D021182
SNOMED-CT 64 420174000
UMLS 69 C0949570

Summaries for Wheat Allergy

MalaCards based summary : Wheat Allergy, also known as wheat hypersensitivity, is related to celiac disease 1 and food allergy. An important gene associated with Wheat Allergy is SCP2 (Sterol Carrier Protein 2), and among its related pathways/superpathways is PPAR signaling pathway. The drugs Barley and Micronutrients have been mentioned in the context of this disorder. Affiliated tissues include testes and skin.

Wikipedia : 72 Wheat allergy is an allergy which typically presents itself as a food allergy, but can also be a contact... more...

Related Diseases for Wheat Allergy

Graphical network of the top 20 diseases related to Wheat Allergy:



Diseases related to Wheat Allergy

Symptoms & Phenotypes for Wheat Allergy

Drugs & Therapeutics for Wheat Allergy

Drugs for Wheat Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Barley Approved, Nutraceutical
2 Micronutrients
3
Nickel 7440-02-0 934
4 Trace Elements
5 Antibodies
6 Antibodies, Antinuclear
7 Immunoglobulins
8 Pharmaceutical Solutions

Interventional clinical trials:

(show all 30)

# Name Status NCT ID Phase Drugs
1 Oral Immunotherapy for Wheat Allergy Completed NCT01980992 Phase 1, Phase 2 Wheat OIT
2 Prevalence of Gluten Sensitivity in Irritable Bowel Syndrome: The First Study in Paediatrics. Unknown status NCT02431585
3 Prevalence of Non Celiac Gluten Sensitivity Among Patients Spontaneously Adherent to Gluten Free Diet Unknown status NCT01827566
4 Accuracy Of Skin Prick Test Using In-house Wheat Extract For The Diagnosis Of IgE-mediated Wheat Allergy: A Pilot Study Completed NCT01070368
5 The Natural History of Wheat Hypersensitivity in Thai Children Completed NCT01801748
6 Oral Desensitization to Wheat in School Aged Children Completed NCT01755884
7 Use of Hypoallergenic (H.A.) Cereals in Children With Diagnosed Allergy to Wheat Completed NCT01332084
8 Abdominal Ultrasound Examination in Non-celiac Wheat Sensitivity Completed NCT03017274
9 Duodenal and Rectal Histology in Non-celiac Wheat Sensitivity and Irritable Bowel Syndrome Patients Completed NCT03022994
10 Effects of Ancient Grains-based Diet in a Closed Community Completed NCT03020511
11 Nickel Allergy and Systemic Nickel Allergy Syndrome in Non Celiac Wheat Sensitivity Completed NCT02750735
12 Self-reported Gluten Sensitivity in High-school Students Completed NCT03021148
13 Non-Celiac Wheat Sensitivity: Permanent or Transient Condition? Completed NCT02823522
14 Autoimmune Diseases And Serum Anti-Nuclear Antibodies Positivity In Non-Celiac Wheat Sensitivity Patients Completed NCT02248545
15 Bioelectrical Impedance Analysis of Not-celiac Wheat Sensitivity Patients Completed NCT01762566
16 Specific Oral Tolerance Induction (SOTI) to Children With IgE-mediated Wheat Allergy Recruiting NCT03352193
17 Evaluation of Potential Allergenicity of New Wheat Varieties Recruiting NCT02341040
18 Food Challenge With Barley Starch as Active Comparator Recruiting NCT03352856
19 Gluten Ingestion Biomarkers in Patients w Gluten Sensitivity and Healthy Controls Peptides in Patients With Non-celiac Gluten Sensitivity and Healthy Patients: A Placebo-controlled Study Recruiting NCT02936297
20 Gynaecological Disorders in Not-celiac Wheat Sensitivity Recruiting NCT03027492
21 Lactose Intolerance and Cow's Milk Protein Allergy in Non-celiac Wheat Sensitivity Patients Recruiting NCT03008252
22 Response to Different Wheat Genotypes in Not-celiac Wheat Sensitivity Recruiting NCT03024775
23 Non Coeliac Gluten Sensitivity in Children Recruiting NCT02895438
24 Diagnostic Significance of Positive EmA Antibodies in the Duodenal Culture Medium of Not-Celiac Wheat Sensitivity (NCWS) Recruiting NCT02203201
25 Bio-markers of Not-celiac Wheat Sensitivity Recruiting NCT01762579
26 Changes in Intestinal Permeability 4 Hours After Gluten Challenge Recruiting NCT03288831
27 Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 2 Recruiting NCT02761785
28 The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults Active, not recruiting NCT01822353
29 Fibromyalgia-like Joint/Muscle Pain and Synovitis in Non-celiac Wheat Sensitivity Patients Not yet recruiting NCT03022513
30 Inflammatory Back Pain and Gluten Free Diet Not yet recruiting NCT03017716

Search NIH Clinical Center for Wheat Allergy

Cochrane evidence based reviews: wheat hypersensitivity

Genetic Tests for Wheat Allergy

Anatomical Context for Wheat Allergy

MalaCards organs/tissues related to Wheat Allergy:

38
Testes, Skin

Publications for Wheat Allergy

Articles related to Wheat Allergy:

(show all 37)
# Title Authors Year
1
Development of a prediction model for severe wheat allergy. ( 28892577 )
2017
2
Antibody reactivity in patients with IgE-mediated wheat allergy to various subunits and fractions of gluten and non-gluten proteins from I8-gliadin-free wheat genotypes. ( 28664699 )
2017
3
What Do We Know Now about IgE-Mediated Wheat Allergy in Children? ( 28054973 )
2017
4
Classification of cutaneous manifestations in patients with non-celiac gluten sensitivity (NCGS) and wheat allergy (WA). ( 29246823 )
2017
5
A three-level stepwise oral food challenge for egg, milk, and wheat allergy. ( 28847653 )
2017
6
Systematic review: Early infant feeding practices and the risk of wheat allergy. ( 28514046 )
2017
7
Immunotherapy for IgE-mediated wheat allergy. ( 28895784 )
2017
8
Clinical presentation, allergens, and management of wheat allergy. ( 26800201 )
2016
9
Wheat Allergy and Intolerence; Recent Updates and Perspectives. ( 24915366 )
2016
10
Wheat allergy: diagnosis and management. ( 26889090 )
2016
11
Food IgG4 antibodies are elevated not only in children with wheat allergy but also in children with gastrointestinal diseases. ( 27004959 )
2016
12
Very low prevalence of IgE mediated wheat allergy and high levels of cross-sensitisation between grass and wheat in a UK birth cohort. ( 27335632 )
2016
13
Remission rate of patients with wheat allergy sensitized to hydrolyzed wheat protein in facial soap. ( 26666491 )
2016
14
Age of Resolution from IgE-Mediated Wheat Allergy. ( 27543738 )
2016
15
Wheat allergy in celiac children. ( 26360318 )
2016
16
THE COMPARISON OF EFFECTIVENESS OF SLOW SPECIFIC ORAL IMMUNOTHERAPY FOR WHEAT ALLERGY USING TWO DIFFERENT INTAKE FREQUENCY. ( 27616175 )
2016
17
INCIDENCE OF APNEA ATTACK AS ALLERGIC REACTION AFTER ORAL FOOD CHALLENGE IN PATIENT WITH IgE-MEDIATED WHEAT ALLERGY. ( 27616176 )
2016
18
Celiac Disease, Wheat Allergy, and Non-Celiac Gluten Sensitivity: What's the Difference? ( 27363231 )
2016
19
Better management of wheat allergy using a very low-dose food challenge: A retrospective study. ( 26666490 )
2016
20
Wheat allergy in a pediatric population from the Mediterranean area. ( 26177963 )
2015
21
Current Trends and Investigative Developments in Wheat Allergy. ( 26241163 )
2015
22
Eighteen cases of wheat allergy and wheat-dependent exercise-induced urticaria/anaphylaxis sensitized by hydrolyzed wheat protein in soap. ( 26096789 )
2015
23
IgE reactivity to carbohydrate moieties of glycoproteins in wheat allergy. ( 25976436 )
2015
24
Wheat allergy in children evaluated with challenge and IgE antibodies to wheat components. ( 25601168 )
2015
25
Diagnosis of gluten related disorders: Celiac disease, wheat allergy and non-celiac gluten sensitivity. ( 26109797 )
2015
26
Current trends and investigative developments in wheat allergy. ( 26288112 )
2015
27
A curious case of exercise-induced wheat allergy in adulthood. ( 24765886 )
2014
28
Oral immunotherapy in children with IgE-mediated wheat allergy: outcome and molecular changes. ( 25219106 )
2014
29
A new reliable method for detecting specific IgE antibodies in the patients with immediate type wheat allergy due to hydrolyzed wheat protein: correlation of its titer and clinical severity. ( 24759554 )
2014
30
Epidemiological link between wheat allergy and exposure to hydrolyzed wheat protein in facial soap. ( 25040662 )
2014
31
The natural history of IgE mediated wheat allergy in children with dominant gastrointestinal symptoms. ( 24572171 )
2014
32
Wheat allergy in children - new tools for diagnostics. ( 25146380 )
2014
33
Wheat allergy. ( 19318930 )
2009
34
The natural history of wheat allergy. ( 19492663 )
2009
35
Antigen-induced expression of CD203c on basophils predicts IgE-mediated wheat allergy. ( 19240377 )
2009
36
[Effect of hypoallergenic wheat (HAW-A1) on atopic dermatitis (AD) with wheat allergy, and its antigenic analysis using sera from patients with AD]. ( 8067902 )
1994
37
Masked type I wheat allergy. Relation to exercise-induced anaphylaxis. ( 3977357 )
1985

Variations for Wheat Allergy

Expression for Wheat Allergy

Search GEO for disease gene expression data for Wheat Allergy.

Pathways for Wheat Allergy

Pathways related to Wheat Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.48 FABP2 SCP2

GO Terms for Wheat Allergy

Molecular functions related to Wheat Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transferase activity, transferring acyl groups GO:0016746 8.62 SCP2 TGM2

Sources for Wheat Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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