Aliases & Classifications for Whiplash

Aliases & Descriptions for Whiplash:

Name: Whiplash 51

Summaries for Whiplash

NINDS : 51 Whiplash-a soft tissue injury to the neck-is also called neck sprain or neck strain. It is characterized by a collection of symptoms that occur following damage to the neck, usually because of sudden extension and flexion. The disorder commonly occurs as the result of an automobile accident and may include injury to intervertebral joints, discs, and ligaments, cervical muscles, and nerve roots. Symptoms such as neck pain may be present directly after the injury or may be delayed for several days. In addition to neck pain, other symptoms may include neck stiffness, injuries to the muscles and ligaments (myofascial injuries), headache, dizziness, abnormal sensations such as burning or prickling (paresthesias), or shoulder or back pain. In addition, some people experience cognitive, somatic, or psychological conditions such as memory loss, concentration impairment, nervousness/irritability, sleep disturbances, fatigue, or depression.

MalaCards based summary : Whiplash is related to cervicitis and headache. An important gene associated with Whiplash is CCL5 (C-C Motif Chemokine Ligand 5), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. The drugs Norepinephrine and Citalopram have been mentioned in the context of this disorder. Affiliated tissues include testes, eye and spinal cord.

Related Diseases for Whiplash

Diseases related to Whiplash via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
id Related Disease Score Top Affiliating Genes
1 cervicitis 10.5
2 headache 10.2
3 chronic pain 10.2
4 constant exophthalmos 10.1 CCL4 CCL5
5 chronic cervicitis 10.1 CCL5 CCR5
6 primary optic atrophy 10.1 CCL4 CCL5
7 hydrops of gallbladder 10.1 CCL5 CCR5
8 orofacial granulomatosis 10.1 CCL5 CCR5
9 retinal ischemia 10.1 CCL5 CCR5
10 chronic subinvolution of uterus 10.1 CCL5 IL16
11 mixed mineral dust pneumoconiosis 10.1 CCL5 IL16
12 hypercementosis 10.0 CCL3 CCL5
13 kcnq3-related disorders 10.0 CCL4 CCR5
14 middle lobe syndrome 10.0 CCL3 CCL4
15 bare lymphocyte syndrome, type i 9.9 CCL3 CCL5
16 anterior foramen magnum meningioma 9.9 CCL3 CCR5
17 pulmonary tuberculosis 9.9 CCL3 CCL5
18 osteodysplasty precocious of danks mayne and kozlowski 9.9 CCL3 CCL5 CCR5
19 advanced sleep phase syndrome, familial, 1 9.8 CCL3 CCL5 CCR5
20 steroid dehydrogenase deficiency dental anomalies 9.8 CCL3 CCL4 CCL5
21 complex regional pain syndrome 9.8 CCL3 CCL4 CCL5
22 aortic aneurysm, familial thoracic 6 9.8 CCL3 CCL4 CCL5
23 pigmentation disease 9.8 CCL3 CCL5
24 thoracic outlet syndrome 9.8
25 cerebritis 9.8
26 radiculopathy 9.8
27 back pain 9.8
28 brain injury 9.8
29 traumatic brain injury 9.8
30 active peptic ulcer disease 9.7 CCL3 CCL4 CCL5 CCR5
31 anus leiomyosarcoma 9.7 CCL3 CCL4 CCL5 CCR5
32 exophthalmos 9.7 CCL3 CCL4 CCL5 CCR5
33 graft-versus-host disease, protection against 9.6 CCL3 CCL4 CCL5 CCR5
34 transient global amnesia 9.6
35 neuroma 9.6
36 occipital neuralgia 9.6
37 post-traumatic stress disorder 9.6
38 neurogenic thoracic outlet syndrome 9.6
39 dermatitis 9.6
40 toxic encephalopathy 9.6
41 carotid artery dissection 9.6
42 cerebrospinal fluid leak 9.6
43 perilymphatic fistula 9.6
44 spinal cord injury 9.6
45 encephalopathy 9.6
46 head injury 9.6
47 acoustic neuroma 9.6
48 nemaline myopathy 2, autosomal recessive 9.6 CCL3 CCL5 IL16 KNG1
49 eating seizures 9.1 CCL3 CCL4 CCL5 CCR5 IL16 KNG1

Graphical network of the top 20 diseases related to Whiplash:



Diseases related to Whiplash

Symptoms & Phenotypes for Whiplash

Drugs & Therapeutics for Whiplash

Drugs for Whiplash (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Norepinephrine Approved Phase 4 51-41-2 439260
2
Citalopram Approved Phase 4 59729-33-8 2771
3 Anesthetics Phase 4
4 Peripheral Nervous System Agents Phase 4,Phase 2
5 Central Nervous System Depressants Phase 4,Phase 2
6
Serotonin Phase 4 50-67-9 5202
7 Muscarinic Antagonists Phase 4
8 Cholinergic Agents Phase 4
9 Cholinergic Antagonists Phase 4
10 Serotonin Agents Phase 4
11 Adrenergic Agents Phase 4,Phase 2
12 Serotonin Uptake Inhibitors Phase 4
13 Neurotransmitter Agents Phase 4,Phase 2
14 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2
15 Parasympatholytics Phase 4
16 Antidepressive Agents Phase 4,Phase 2
17 Antidepressive Agents, Second-Generation Phase 4
18 Psychotropic Drugs Phase 4,Phase 2
19 Atomoxetine Hydrochloride Phase 4
20 Autonomic Agents Phase 4
21 Antiparkinson Agents Phase 4
22
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754 657311
23
Ethanol Approved Phase 2 64-17-5 702
24
Ibuprofen Approved Phase 2 15687-27-1 3672
25
Amitriptyline Approved Phase 2 50-48-6 2160
26
Cyclobenzaprine Approved Phase 2 303-53-7 2895
27
Butyric Acid Experimental Phase 2 107-92-6 264
28 Analgesics Phase 2
29 Cortisol succinate Phase 2
30 Analgesics, Non-Narcotic Phase 2
31 Hydrocortisone 17-butyrate 21-propionate Phase 2
32 Hydrocortisone acetate Phase 2
33 Hydrocortisone-17-butyrate Phase 2
34 Anti-Inflammatory Agents Phase 2
35 Anti-Inflammatory Agents, Non-Steroidal Phase 2
36 Antirheumatic Agents Phase 2
37 Neuromuscular Agents Phase 2
38 Cyclooxygenase Inhibitors Phase 2
39 Amitriptyline, perphenazine drug combination Phase 2
40 Tranquilizing Agents Phase 2
41 Antidepressive Agents, Tricyclic Phase 2
42
Triamcinolone Approved, Vet_approved 124-94-7 31307
43
Levobupivacaine Approved 27262-47-1 92253
44
Mannitol Approved, Investigational 69-65-8 453 6251
45
Imidacloprid 105827-78-9 86418
46 triamcinolone acetonide
47 Triamcinolone diacetate
48 Triamcinolone hexacetonide
49 Vaccines Early Phase 1
50 Pharmaceutical Solutions

Interventional clinical trials:

(show all 47)
id Name Status NCT ID Phase
1 Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders Completed NCT01601912 Phase 4
2 Pulsed Electromagnetic Fields (PEMF) and Post-Axillary Surgery Morbidity Terminated NCT01255631 Phase 4
3 Lidocaine Injection Versus Sham Needling in Treating Whiplash Associated Disorder Withdrawn NCT02060734 Phase 4
4 PEMF Effects on Pain After Abdominal Body Contouring Withdrawn NCT01762423 Phase 4
5 University Health Network Whiplash Intervention Trial Completed NCT00546806 Phase 3
6 Preventing Chronic Whiplash Pain Completed NCT00021476 Phase 3
7 Comparison of the Effect of Neck Collar, Act-as-Usual, and Active Mobilisation Early After a Whiplash Injury Completed NCT00206271 Phase 3
8 Manual Therapy Dosage Factorial Study Withdrawn NCT00560807 Phase 2, Phase 3
9 Association Between Low Cortisol Levels and Whiplash Syndrome Unknown status NCT02090309 Phase 2
10 Does Acupuncture Activate Endogenous Pain Inhibition in Chronic Whiplash? Completed NCT01512576 Phase 2
11 Acupuncture for Whiplash Associated Disorder Completed NCT01395511 Phase 2
12 Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial Completed NCT00790270 Phase 2
13 Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain Completed NCT01518530 Phase 2
14 East-West Collaborative Medicine Using Bee-Venom Acupuncture on Whiplash-Associated Disorders Unknown status NCT01369238
15 Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash Unknown status NCT01544075 Early Phase 1
16 Treatment of Whiplash Associated Disorders by APOS Kit Unknown status NCT00266981
17 Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain Unknown status NCT01172795
18 A Clinical Comparison in Cervical Epidural Pressure Changes Between Midline and Paramedian Approaches Unknown status NCT01360138
19 Neuroscience Education on Osteoarthritis Unknown status NCT02246088
20 RFD Versus Cervical Medial Branch Blocks in Chronic Degenerative Neck Pain Unknown status NCT01743326
21 Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study Unknown status NCT00510757
22 Measuring the Impact of the French Version of the Whiplash Book Completed NCT03040245
23 Effects of Different Exercise Programs for People With Chronic Whiplash Associated Disorders Completed NCT01528579
24 Manual Therapy to Treat Acute Whiplash Injury Completed NCT01825460
25 Neck Muscle Activation in Patients With Long Standing Problems After a Whiplash Trauma Registered With Ultrasound With Speckle Tracking Completed NCT01547624
26 Randomized WAD Study Completed NCT01994044
27 Neck Exercises, Training and Pain Management as a Treatment for Whiplash Patients With Chronic Neck Pain Completed NCT01431261
28 Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study Completed NCT01957033
29 Icing Effects on Neck Functions of the Boxers Completed NCT01203280
30 Explain Pain in Fibromyalgia Patients Completed NCT02474875
31 Pain Neuroscience Education Combined With Cognition-targeted Motor Control Training Completed NCT02098005
32 The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion Completed NCT02691143
33 Effectiveness of an Educational Video Following Acute Whiplash Trauma Recruiting NCT01699334
34 Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders Recruiting NCT02251028
35 Whiplash-associated Disorders - Needling Treatments Pilot Study Recruiting NCT01824810
36 Is Chronic Whiplash-associated Pain of Neurogenic Origin? Recruiting NCT02692937
37 Neck-specific Exercise in Chronic Whiplash Recruiting NCT03022812
38 Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries Recruiting NCT02157038 Early Phase 1
39 Modeling Post-traumatic Pain and Recovery: The SYMBIOME Longitudinal Cohort Study Recruiting NCT02711085
40 Correlation Between Central Sensitization Inventory and Posturographic Data Enrolling by invitation NCT03058003
41 Why Does Acute Post Whiplash Injury Pain Transform Into Chronic Pain? Not yet recruiting NCT02560675
42 Investigating the Effect of an Information Video for Neck Injuries in a Emergency Department Setting Not yet recruiting NCT02570659
43 Central Sensitization in Chronic Whiplash Patients Not yet recruiting NCT03005691
44 Free Fall Acrobatics to Reduce Neck Loads During Parachute Opening Shock: Evaluation of an Intervention. Not yet recruiting NCT02625896
45 Influence of Beliefs on the Prognosis of Chronic Musculoskeletal Pain. Not yet recruiting NCT03036553
46 Maastricht Neck Study: Cervical Range of Motion in Whiplash Patients Terminated NCT00952510
47 Observational Study of the BrainScope® Ahead™ M-100 in UK Emergency Department Patients With Head Injury Terminated NCT01430988

Search NIH Clinical Center for Whiplash

Genetic Tests for Whiplash

Anatomical Context for Whiplash

MalaCards organs/tissues related to Whiplash:

39
Testes, Eye, Spinal Cord, Bone, Brain, Tongue, Skin

Publications for Whiplash

Articles related to Whiplash:

(show top 50) (show all 602)
id Title Authors Year
1
The long-term course of deficient cervical kinaesthesia following a whiplash injury has a tendency to seek a physiological homeostasis. A prospective study. ( 26778601 )
2016
2
Satisfaction With the Outcome of Physical Therapist-Prescribed Exercise in Chronic Whiplash-Associated Disorders: Secondary Analysis of a Randomized Clinical Trial. ( 27374016 )
2016
3
Thoracic dysfunction in whiplash-associated disorders: a systematic review and meta-analysis protocol. ( 26860082 )
2016
4
The relationship between insurance claim closure and recovery after traffic injuries for individuals with whiplash associated disorders. ( 27207822 )
2016
5
Chronic Whiplash-Associated Disorders: Reorganization of the Brain? ( 27539066 )
2016
6
Streaky, whiplash-like erythema and succulent papules: flagellate dermatitis following consumption of Auricularia auricula-judae. ( 26972199 )
2016
7
An Investigation of Fat Infiltration of the Multifidus Muscle in Patients With Severe Neck Symptoms Associated With Chronic Whiplash Associated Disorder. ( 27590177 )
2016
8
Altered Regional Cerebral Blood Flow in Chronic Whiplash Associated Disorders. ( 27444853 )
2016
9
Morphology of Cervical Spine Meniscoids in Individuals With Chronic Whiplash Associated Disorder: A Case-Control Study. ( 27594664 )
2016
10
Multivariate analysis of ultrasound-recorded dorsal strain sequences: Investigation of dynamic neck extensions in women with chronic whiplash associated disorders. ( 27484361 )
2016
11
Acute Whiplash Injury Study (AWIS): a protocol for a cluster randomised pilot and feasibility trial of an Active Behavioural Physiotherapy Intervention in an insurance private setting. ( 27412105 )
2016
12
Economic and Health-Related Quality of Life Outcomes of Whiplash Associated Disorders. ( 26909831 )
2016
13
Transient pressure changes in the vertebral canal during whiplash motion - A hydrodynamic modeling approach. ( 26827171 )
2016
14
Effects of Stress and Relaxation on Central Pain Modulation in Chronic Whiplash and Fibromyalgia Patients Compared to Healthy Controls. ( 27008285 )
2016
15
Pain-catastrophizing and fear-avoidance beliefs as mediators between post-traumatic stress symptoms and pain following whiplash injury - A prospective cohort study. ( 26919333 )
2016
16
Recovery Pathways and Prognosis After Whiplash Injury. ( 27594661 )
2016
17
Stressful events and coping related to acute and sub-acute whiplash-associated disorders. ( 26985631 )
2016
18
Effect of Early Intensive Care on Recovery From Whiplash-Associated Disorders: Results of a Population-Based Cohort Study. ( 26808783 )
2016
19
Addition of posttraumatic stress and sensory hypersensitivity more accurately estimates disability and pain than fear avoidance measures alone following whiplash injury. ( 27007066 )
2016
20
Abnormal Pain Response to Visual Feedback During Cervical Movements in Chronic Whiplash: An Experimental Study. ( 26913494 )
2016
21
Predicting nonrecovery among whiplash patients in the emergency room and in an insurance company setting. ( 27405822 )
2016
22
The pain drawing as an instrument for identifying cervical spine nerve involvement in chronic whiplash-associated disorders. ( 27358576 )
2016
23
Perceived pain extent is associated with disability, depression and self-efficacy in individuals with whiplash-associated disorders. ( 27149920 )
2016
24
Are People With Whiplash Associated Neck Pain Different to People With Non-Specific Neck Pain? ( 27594663 )
2016
25
The Role of the Trigemino Cervical Complex in Chronic Whiplash Associated Headache: A Cross Sectional Study. ( 27091393 )
2016
26
Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: What Works for Chronic Whiplash-Associated Disorders: Neck-Specific Exercises With or Without Behavioral Modification? ( 26829072 )
2016
27
The effect of neck-specific exercise with or without a behavioral approach on psychological factors in chronic whiplash-associated disorders: A randomized controlled trial with a 2-year follow-up. ( 27559950 )
2016
28
Confirmatory Factor Analysis and Multiple Linear Regression of the Neck Disability Index: Assessment If Subscales Are Equally Relevant in Whiplash and Nonspecific Neck Pain. ( 27330510 )
2016
29
Vibration sensibility of the median nerve in a population with chronic whiplash associated disorder: Intra- and inter-rater reliability study. ( 27422601 )
2016
30
General practitioners knowledge and management of whiplash associated disorders and post-traumatic stress disorder: implications for patient care. ( 27440111 )
2016
31
Intra and Inter-Rater Reliability and Convergent Validity of FIT-HaNSA in Individuals with Grade D9 Whiplash Associated Disorder. ( 27350797 )
2016
32
Erratum to 'StressModEx - Physiotherapist-led Stress Inoculation Training integrated with exercise for acute whiplash injury: study protocol for a randomised controlled trial' [JPHYS 61/3 (2015) 157]. ( 27056791 )
2016
33
Implementation of a guideline-based clinical pathway of care to improve health outcomes following whiplash injury (Whiplash ImPaCT): protocol of a randomised, controlled trial. ( 26996096 )
2016
34
Changes in Dorsal Neck Muscle Function in Individuals with Chronic Whiplash-Associated Disorders: A Real-Time Ultrasound Case-Control Study. ( 26921149 )
2016
35
Chronic Whiplash Associated Disorders (WAD): Responses to Nerve Blocks of Cervical Zygapophyseal Joints. ( 27018055 )
2016
36
Confirmatory factor analysis of the neck disability index, comparing patients with whiplash associated disorders to a control group with non-specific neck pain. ( 27040281 )
2016
37
Development of an active behavioural physiotherapy intervention (ABPI) for acute whiplash-associated disorder (WAD) II management: a modified Delphi study. ( 27630069 )
2016
38
The tongue after whiplash: case report and osteopathic treatment. ( 27462180 )
2016
39
Pharmacological and Interventional Management of Pain After Whiplash Injury. ( 27594660 )
2016
40
Classifying Whiplash Recovery Status Using the Neck Disability Index: Optimized Cutoff Points Derived From Receiver Operating Characteristic. ( 27330511 )
2016
41
Initial healthcare and coping preferences are associated with outcome 1a88year after whiplash trauma: a multicentre 1-year follow-up study. ( 25795697 )
2015
42
Trauma-focused cognitive behaviour therapy and exercise for chronic whiplash: protocol of a randomised, controlled trial. ( 26319283 )
2015
43
External validation of a clinical prediction rule to predict full recovery and ongoing moderate/severe disability following acute whiplash injury. ( 25827122 )
2015
44
Low Pain Catastrophization and Disability Predict Successful Outcome to Radiofrequency Neurotomy in Individuals with Chronic Whiplash. ( 25594839 )
2015
45
The Rapid and Progressive Degeneration of the Cervical Multifidus in Whiplash: A MRI study of Fatty Infiltration. ( 25785961 )
2015
46
Altered ventral neck muscle deformation for individuals with whiplash associated disorder compared to healthy controls - A case-control ultrasound study. ( 25454684 )
2015
47
Identifying upper limb disability in patients with persistent whiplash. ( 25554214 )
2015
48
Mechanical properties of the trapezius during scapular elevation in people with chronic whiplash associated disorders - A case-control ultrasound speckle tracking analysis. ( 26277485 )
2015
49
Factors associated with work ability in patients with chronic whiplash-associated disorder grade II-III: A cross-sectional analysis. ( 25882646 )
2015
50
The Impact of Posttraumatic Stress Disorder on Physiological Arousal, Disability and Sensory Pain Thresholds in Patients with Chronic Whiplash. ( 26560075 )
2015

Variations for Whiplash

Expression for Whiplash

Search GEO for disease gene expression data for Whiplash.

Pathways for Whiplash

Pathways related to Whiplash according to GeneCards Suite gene sharing:

(show all 13)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.23 CCL3 CCL4 CCL5 CCR5 IL16
2
Show member pathways
13 CCL3 CCL4 CCL5 CCR5 IL16
3
Show member pathways
12.91 CCL3 CCL4 CCL5 CCR5 IL16
4
Show member pathways
12.83 CCL3 CCL4 CCL5 CCR5 IL16
5
Show member pathways
12.49 CCL3 CCL4 CCL5 CCR5
6
Show member pathways
11.55 CCL3 CCL4 CCR5
7 11.48 CCL3 CCL5
8 11.44 CCL3 CCL4
9
Show member pathways
11.35 CCL3 CCL4 CCL5 CCR5
10 11.23 CCL3 CCL4 CCL5
11
Show member pathways
11.08 CCL3 CCL4
12 10.69 CCL3 CCL4 CCL5 IL16
13 10.61 CCL3 CCL4 CCL5 CCR5

GO Terms for Whiplash

Cellular components related to Whiplash according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CCL3 CCL4 CCL5 IL16 KNG1
2 extracellular space GO:0005615 9.02 CCL3 CCL4 CCL5 IL16 KNG1

Biological processes related to Whiplash according to GeneCards Suite gene sharing:

(show all 32)
id Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor signaling pathway GO:0007186 9.94 CCL3 CCL4 CCL5 CCR5
2 MAPK cascade GO:0000165 9.81 CCL3 CCL5 CCR5
3 cell-cell signaling GO:0007267 9.8 CCL3 CCL4 CCL5 CCR5
4 immune response GO:0006955 9.8 CCL3 CCL4 CCL5 CCR5 IL16
5 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.79 CCL3 CCL4 CCL5
6 calcium ion transport GO:0006816 9.77 CCL3 CCL5 CCR5
7 cellular response to tumor necrosis factor GO:0071356 9.75 CCL3 CCL4 CCL5
8 inflammatory response GO:0006954 9.72 CCL3 CCL4 CCL5 CCR5 KNG1
9 response to toxic substance GO:0009636 9.71 CCL3 CCL4 CCL5
10 cellular response to interleukin-1 GO:0071347 9.69 CCL3 CCL4 CCL5
11 cellular calcium ion homeostasis GO:0006874 9.65 CCL3 CCL5
12 cellular response to organic cyclic compound GO:0071407 9.65 CCL3 CCL5
13 cell chemotaxis GO:0060326 9.65 CCL3 CCL5
14 neutrophil chemotaxis GO:0030593 9.65 CCL3 CCL4 CCL5
15 calcium-mediated signaling GO:0019722 9.64 CCL3 CCR5
16 positive chemotaxis GO:0050918 9.63 CCL3 CCL5
17 cellular response to interferon-gamma GO:0071346 9.63 CCL3 CCL4 CCL5
18 protein kinase B signaling GO:0043491 9.62 CCL3 CCL5
19 lipopolysaccharide-mediated signaling pathway GO:0031663 9.62 CCL3 CCL5
20 positive regulation of calcium-mediated signaling GO:0050850 9.61 CCL3 CCL4
21 monocyte chemotaxis GO:0002548 9.61 CCL3 CCL4 CCL5
22 dendritic cell chemotaxis GO:0002407 9.6 CCL5 CCR5
23 macrophage chemotaxis GO:0048246 9.58 CCL3 CCL5
24 response to cholesterol GO:0070723 9.57 CCL3 CCR5
25 signaling GO:0023052 9.56 CCL3 CCR5
26 eosinophil chemotaxis GO:0048245 9.55 CCL3 CCL5
27 positive regulation of calcium ion transport GO:0051928 9.54 CCL3 CCL4 CCL5
28 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 9.52 CCL3 CCR5
29 chemokine-mediated signaling pathway GO:0070098 9.46 CCL3 CCL4 CCL5 CCR5
30 negative regulation by host of viral transcription GO:0043922 9.43 CCL3 CCL4 CCL5
31 positive regulation of natural killer cell chemotaxis GO:2000503 9.13 CCL3 CCL4 CCL5
32 chemotaxis GO:0006935 9.02 CCL3 CCL4 CCL5 CCR5 IL16

Molecular functions related to Whiplash according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.46 CCL3 CCL4 CCL5 IL16
2 chemokine activity GO:0008009 9.43 CCL3 CCL4 CCL5
3 phosphatidylinositol phospholipase C activity GO:0004435 9.4 CCL5 CCR5
4 chemoattractant activity GO:0042056 9.37 CCL3 CCL5
5 phospholipase activator activity GO:0016004 9.32 CCL3 CCL5
6 CCR5 chemokine receptor binding GO:0031730 9.13 CCL3 CCL4 CCL5
7 CCR1 chemokine receptor binding GO:0031726 8.8 CCL3 CCL4 CCL5

Sources for Whiplash

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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