Aliases & Classifications for Whiplash

MalaCards integrated aliases for Whiplash:

Name: Whiplash 51

Summaries for Whiplash

NINDS : 51 Whiplash-a soft tissue injury to the neck-is also called neck sprain or neck strain. It is characterized by a collection of symptoms that occur following damage to the neck, usually because of sudden extension and flexion. The disorder commonly occurs as the result of an automobile accident and may include injury to intervertebral joints, discs, and ligaments, cervical muscles, and nerve roots. Symptoms such as neck pain may be present directly after the injury or may be delayed for several days. In addition to neck pain, other symptoms may include neck stiffness, injuries to the muscles and ligaments (myofascial injuries), headache, dizziness, abnormal sensations such as burning or prickling (paresthesias), or shoulder or back pain. In addition, some people experience cognitive, somatic, or psychological conditions such as memory loss, concentration impairment, nervousness/irritability, sleep disturbances, fatigue, or depression.

MalaCards based summary : Whiplash is related to carotid artery dissection and cervicitis. An important gene associated with Whiplash is CCL5 (C-C Motif Chemokine Ligand 5), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. The drugs Citalopram and Norepinephrine have been mentioned in the context of this disorder. Affiliated tissues include testes, eye and spinal cord.

Related Diseases for Whiplash

Diseases related to Whiplash via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
id Related Disease Score Top Affiliating Genes
1 carotid artery dissection 28.0 CCL3 CCL4 CCL5 CCR5
2 cervicitis 10.5
3 chronic cervicitis 10.3 CCL5 CCR5
4 chronic inflammation of lacrimal passage 10.3 CCL4 CCL5
5 gonococcal endophthalmia 10.3 CCL5 CCR5
6 orbital melanoma 10.3 CCL5 CCR5
7 fanconi syndrome 10.3 CCL4 CCL5
8 renal tubular acidosis 10.3 CCL5 CCR5
9 chronic pain 10.2
10 headache 10.2
11 chronic subinvolution of uterus 10.2 CCL5 IL16
12 pneumoconiosis 10.1 CCL5 IL16
13 hypercementosis 10.0 CCL3 CCL5
14 intracranial hypertension 9.9 CCL5 IL16
15 lower urinary tract calculus 9.9 CCL5 CCR5
16 ragweed sensitivity 9.9 CCL3 CCL5
17 inner ear disease 9.9 CCL3 CCL5
18 nonspecific interstitial pneumonia 9.8 CCL3 CCL4
19 hyperpigmentation of eyelid 9.8 CCL3 CCL5
20 inflammatory bowel disease 3 9.8 CCL3 CCL5
21 brain injury 9.8
22 traumatic brain injury 9.8
23 thoracic outlet syndrome 9.8
24 cerebritis 9.8
25 radiculopathy 9.8
26 back pain 9.8
27 acral lentiginous melanoma 9.7 CCL3 CCR5
28 spinal cord injury 9.6
29 acoustic neuroma 9.6
30 transient global amnesia 9.6
31 neuroma 9.6
32 post-traumatic stress disorder 9.6
33 dermatitis 9.6
34 toxic encephalopathy 9.6
35 cerebrospinal fluid leak 9.6
36 perilymphatic fistula 9.6
37 encephalopathy 9.6
38 head injury 9.6
39 occipital neuralgia 9.6
40 neurogenic thoracic outlet syndrome 9.6
41 oropharyngeal cancer, childhood 9.6 CCL3 CCL5 CCR5
42 advanced sleep phase syndrome, familial, 1 9.5 CCL3 CCL5 CCR5
43 stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features 9.5 CCL3 CCL4 CCL5
44 causalgia 9.5 CCL3 CCL4 CCL5
45 diamond-blackfan anemia 3 9.4 CCL3 CCL4 CCL5
46 myocardial infarction 9.3 CCL5 CCR5 KNG1
47 cataract 29, coralliform 9.2 CCL3 CCL5 CCR5
48 malaria 9.1 CCL3 CCL4 CCL5
49 duodenal somatostatinoma 9.1 CCL3 CCL4 CCL5 CCR5
50 heart sarcoma 9.0 CCL3 CCL4 CCL5 CCR5

Graphical network of the top 20 diseases related to Whiplash:



Diseases related to Whiplash

Symptoms & Phenotypes for Whiplash

Drugs & Therapeutics for Whiplash

Drugs for Whiplash (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 54)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Citalopram Approved Phase 4 59729-33-8 2771
2
Norepinephrine Approved Phase 4 51-41-2 439260
3 Peripheral Nervous System Agents Phase 4,Phase 2
4 Anesthetics Phase 4
5 Central Nervous System Depressants Phase 4,Phase 2
6 Adrenergic Agents Phase 4,Phase 2
7 Antidepressive Agents Phase 4,Phase 2
8 Antidepressive Agents, Second-Generation Phase 4
9 Antiparkinson Agents Phase 4
10 Atomoxetine Hydrochloride Phase 4
11 Autonomic Agents Phase 4
12 Cholinergic Agents Phase 4
13 Cholinergic Antagonists Phase 4
14 Muscarinic Antagonists Phase 4
15 Neurotransmitter Agents Phase 4,Phase 2
16 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2
17 Parasympatholytics Phase 4
18 Psychotropic Drugs Phase 4,Phase 2
19
Serotonin Phase 4 50-67-9 5202
20 Serotonin Agents Phase 4
21 Serotonin Uptake Inhibitors Phase 4
22
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754 657311
23
Ethanol Approved Phase 2 64-17-5 702
24
Amitriptyline Approved Phase 2 50-48-6 2160
25
Cyclobenzaprine Approved Phase 2 303-53-7 2895
26
Ibuprofen Approved Phase 2 15687-27-1 3672
27
Butyric Acid Experimental Phase 2 107-92-6 264
28 Anti-Inflammatory Agents Phase 2
29 Cortisol succinate Phase 2
30 Hydrocortisone 17-butyrate 21-propionate Phase 2
31 Hydrocortisone acetate Phase 2
32 Hydrocortisone-17-butyrate Phase 2
33 Analgesics Phase 2
34 Analgesics, Non-Narcotic Phase 2
35 Anti-Inflammatory Agents, Non-Steroidal Phase 2
36 Antirheumatic Agents Phase 2
37 Amitriptyline, perphenazine drug combination Phase 2
38 Antidepressive Agents, Tricyclic Phase 2
39 Cyclooxygenase Inhibitors Phase 2
40 Neuromuscular Agents Phase 2
41 Tranquilizing Agents Phase 2
42
Mannitol Approved, Investigational 69-65-8 453 6251
43
Levobupivacaine Approved 27262-47-1 92253
44
Triamcinolone Approved, Vet_approved 124-94-7 31307
45 Pyrantel Approved, Vet_approved
46
Menthol Approved 2216-51-5 16666
47
Imidacloprid Vet_approved 105827-78-9 86418
48 Pyranoprofen
49 Pharmaceutical Solutions
50 Vaccines Early Phase 1

Interventional clinical trials:

(show all 48)

id Name Status NCT ID Phase Drugs
1 Unraveling the Nature of Impaired Pain Inhibition in Patients With Chronic Whiplash-associated Disorders Completed NCT01601912 Phase 4 Atomoxetine;Citalopram
2 Pulsed Electromagnetic Fields (PEMF) and Post-Axillary Surgery Morbidity Terminated NCT01255631 Phase 4
3 Lidocaine Injection Versus Sham Needling in Treating Whiplash Associated Disorder Withdrawn NCT02060734 Phase 4
4 PEMF Effects on Pain After Abdominal Body Contouring Withdrawn NCT01762423 Phase 4
5 University Health Network Whiplash Intervention Trial Completed NCT00546806 Phase 3
6 Preventing Chronic Whiplash Pain Completed NCT00021476 Phase 3
7 Comparison of the Effect of Neck Collar, Act-as-Usual, and Active Mobilisation Early After a Whiplash Injury Completed NCT00206271 Phase 3
8 Manual Therapy Dosage Factorial Study Withdrawn NCT00560807 Phase 2, Phase 3
9 Association Between Low Cortisol Levels and Whiplash Syndrome Unknown status NCT02090309 Phase 2 Hydrocortisone;normal saline 0.9%
10 Does Acupuncture Activate Endogenous Pain Inhibition in Chronic Whiplash? Completed NCT01512576 Phase 2
11 Acupuncture for Whiplash Associated Disorder Completed NCT01395511 Phase 2
12 Comparison of Ibuprofen, Cyclobenzaprine, or Both for Acute Cervical Strain: A Randomized Clinical Trial Completed NCT00790270 Phase 2 Cyclobenzaprine;Ibuprofen;Ibuprofen plus Cyclobenzaprine
13 Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain Completed NCT01518530 Phase 2
14 East-West Collaborative Medicine Using Bee-Venom Acupuncture on Whiplash-Associated Disorders Unknown status NCT01369238 zaltoprofen
15 Whiplash-associated Disorders - Needling Treatments Pilot Study Unknown status NCT01824810
16 Investigating the Effect of an Information Video for Neck Injuries in a Emergency Department Setting Unknown status NCT02570659
17 Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash Unknown status NCT01544075 Early Phase 1
18 Treatment of Whiplash Associated Disorders by APOS Kit Unknown status NCT00266981
19 Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain Unknown status NCT01172795
20 A Clinical Comparison in Cervical Epidural Pressure Changes Between Midline and Paramedian Approaches Unknown status NCT01360138
21 Neuroscience Education on Osteoarthritis Unknown status NCT02246088
22 RFD Versus Cervical Medial Branch Blocks in Chronic Degenerative Neck Pain Unknown status NCT01743326
23 Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study Unknown status NCT00510757
24 Measuring the Impact of the French Version of the Whiplash Book Completed NCT03040245
25 Effects of Different Exercise Programs for People With Chronic Whiplash Associated Disorders Completed NCT01528579
26 Manual Therapy to Treat Acute Whiplash Injury Completed NCT01825460
27 Neck Muscle Activation in Patients With Long Standing Problems After a Whiplash Trauma Registered With Ultrasound With Speckle Tracking Completed NCT01547624
28 Randomized WAD Study Completed NCT01994044
29 Neck Exercises, Training and Pain Management as a Treatment for Whiplash Patients With Chronic Neck Pain Completed NCT01431261
30 Responses of People With Neck Pain Being Treated With Varying Doses of Manual Therapy: A Pilot Study Completed NCT01957033
31 Icing Effects on Neck Functions of the Boxers Completed NCT01203280
32 Explain Pain in Fibromyalgia Patients Completed NCT02474875
33 Pain Neuroscience Education Combined With Cognition-targeted Motor Control Training Completed NCT02098005
34 The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion Completed NCT02691143
35 Effectiveness of an Educational Video Following Acute Whiplash Trauma Recruiting NCT01699334
36 Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders Recruiting NCT02251028
37 Why Does Acute Post Whiplash Injury Pain Transform Into Chronic Pain? Recruiting NCT02560675
38 Is Chronic Whiplash-associated Pain of Neurogenic Origin? Recruiting NCT02692937
39 Modern Pain Neuroscience Applied to Chronic Pain in Patients With Chronic Whiplash Associated Disorders Recruiting NCT03239938
40 Neck-specific Exercise in Chronic Whiplash Recruiting NCT03022812
41 Modeling Post-traumatic Pain and Recovery: The SYMBIOME Longitudinal Cohort Study Recruiting NCT02711085
42 Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries Active, not recruiting NCT02157038 Early Phase 1
43 Free Fall Acrobatics to Reduce Neck Loads During Parachute Opening Shock: Evaluation of an Intervention. Enrolling by invitation NCT02625896
44 Correlation Between Central Sensitization Inventory and Posturographic Data Enrolling by invitation NCT03058003
45 Central Sensitization in Chronic Whiplash Patients Not yet recruiting NCT03005691
46 Influence of Beliefs on the Prognosis of Chronic Musculoskeletal Pain. Not yet recruiting NCT03036553
47 Maastricht Neck Study: Cervical Range of Motion in Whiplash Patients Terminated NCT00952510
48 Observational Study of the BrainScope® Ahead™ M-100 in UK Emergency Department Patients With Head Injury Terminated NCT01430988

Search NIH Clinical Center for Whiplash

Genetic Tests for Whiplash

Anatomical Context for Whiplash

MalaCards organs/tissues related to Whiplash:

39
Testes, Eye, Spinal Cord, Brain, Bone, Tongue, Skin

Publications for Whiplash

Articles related to Whiplash:

(show top 50) (show all 621)
id Title Authors Year
1
Association between Clinical and Neurophysiological Outcomes in Patients with Mechanical Neck Pain and Whiplash-associated Disorders. ( 28678060 )
2017
2
Whiplash Syndrome- a disorder of the brain? ( 28697186 )
2017
3
The Qualitative Grading of Muscle Fat Infiltration in Whiplash Using Fat/Water Magnetic Resonance Imaging. ( 28887274 )
2017
4
Whiplash Injury: Perspectives on the Development of Chronic Pain. ( 28759489 )
2017
5
The Whiplash Rash. ( 28761857 )
2017
6
Isometric muscle fatigue of the paravertebral and upper extremity muscles after whiplash injury. ( 28761029 )
2017
7
Effects on jaw function shortly after whiplash trauma. ( 28891205 )
2017
8
How Do We Meet the Challenge of Whiplash? ( 28666398 )
2017
9
Cross-sectional and Prospective Correlates of Recovery Expectancies in the Rehabilitation of Whiplash Injury. ( 28799973 )
2017
10
Motor evoked potentials in patients with chronic whiplash-associated disorder grade II. ( 28711376 )
2017
11
Advancing imaging technologies for patients with spinal pain: with a focus on whiplash injury. ( 28774580 )
2017
12
Epidemiology and psychological factors of whiplash associated disorders in Japanese population. ( 28931977 )
2017
13
Assessment of Range of Movement, Pain and Disability Following a Whiplash Injury. ( 28839498 )
2017
14
Cost-effectiveness of neck-specific exercise with or without a behavioral approach versus physical activity prescription in the treatment of chronic whiplash-associated disorders: Analyses of a randomized clinical trial. ( 28640136 )
2017
15
Women with late whiplash syndrome have greatly reduced load-bearing of the cervical spine. In vivo biomechanical, cross-sectional, lateral radiographic study. ( 28714657 )
2017
16
Exercise induced hypoalgesia is elicited by isometric, but not aerobic exercise in individuals with chronic whiplash associated disorders. ( 28850338 )
2017
17
Lack of Gender and Age Differences in Pain Measurements Following Exercise in People with Chronic Whiplash-Associated Disorders. ( 28934789 )
2017
18
Toward Improving Outcomes in Whiplash: Implementing New Directions of Care. ( 28666399 )
2017
19
Acute Whiplash Injury Study (AWIS): a protocol for a cluster randomised pilot and feasibility trial of an Active Behavioural Physiotherapy Intervention in an insurance private setting. ( 27412105 )
2016
20
Implementation of a guideline-based clinical pathway of care to improve health outcomes following whiplash injury (Whiplash ImPaCT): protocol of a randomised, controlled trial. ( 26996096 )
2016
21
The relationship between insurance claim closure and recovery after traffic injuries for individuals with whiplash associated disorders. ( 27207822 )
2016
22
Abnormal Pain Response to Visual Feedback During Cervical Movements in Chronic Whiplash: An Experimental Study. ( 26913494 )
2016
23
A small group Whiplash-Associated-Disorders (WAD) patients with central neck pain and movement induced stabbing pain, the painful segment determined by mechanical provocation: Fusion surgery was superior to multimodal rehabilitation in a randomized trial. ( 28850488 )
2016
24
Intra and Inter-Rater Reliability and Convergent Validity of FIT-HaNSA in Individuals with Grade D9 Whiplash Associated Disorder. ( 27350797 )
2016
25
The pain drawing as an instrument for identifying cervical spine nerve involvement in chronic whiplash-associated disorders. ( 27358576 )
2016
26
Are People With Whiplash Associated Neck Pain Different to People With Non-Specific Neck Pain? ( 27594663 )
2016
27
Thoracic dysfunction in whiplash-associated disorders: a systematic review and meta-analysis protocol. ( 26860082 )
2016
28
Confirmatory Factor Analysis and Multiple Linear Regression of the Neck Disability Index: Assessment If Subscales Are Equally Relevant in Whiplash and Nonspecific Neck Pain. ( 27330510 )
2016
29
Effects of Stress and Relaxation on Central Pain Modulation in Chronic Whiplash and Fibromyalgia Patients Compared to Healthy Controls. ( 27008285 )
2016
30
Recovery Pathways and Prognosis After Whiplash Injury. ( 27594661 )
2016
31
The tongue after whiplash: case report and osteopathic treatment. ( 27462180 )
2016
32
Changes in Dorsal Neck Muscle Function in Individuals with Chronic Whiplash-Associated Disorders: A Real-Time Ultrasound Case-Control Study. ( 26921149 )
2016
33
Perceived pain extent is associated with disability, depression and self-efficacy in individuals with whiplash-associated disorders. ( 27149920 )
2016
34
Chronic Whiplash Associated Disorders (WAD): Responses to Nerve Blocks of Cervical Zygapophyseal Joints. ( 27018055 )
2016
35
The Role of the Trigemino Cervical Complex in Chronic Whiplash Associated Headache: A Cross Sectional Study. ( 27091393 )
2016
36
Transient pressure changes in the vertebral canal during whiplash motion - A hydrodynamic modeling approach. ( 26827171 )
2016
37
Morphology of Cervical Spine Meniscoids in Individuals With Chronic Whiplash Associated Disorder: A Case-Control Study. ( 27594664 )
2016
38
Chronic Whiplash-Associated Disorders: Reorganization of the Brain? ( 27539066 )
2016
39
Altered Regional Cerebral Blood Flow in Chronic Whiplash Associated Disorders. ( 27444853 )
2016
40
Vibration sensibility of the median nerve in a population with chronic whiplash associated disorder: Intra- and inter-rater reliability study. ( 27422601 )
2016
41
Pain-catastrophizing and fear-avoidance beliefs as mediators between post-traumatic stress symptoms and pain following whiplash injury - A prospective cohort study. ( 26919333 )
2016
42
Stressful events and coping related to acute and sub-acute whiplash-associated disorders. ( 26985631 )
2016
43
Addition of posttraumatic stress and sensory hypersensitivity more accurately estimates disability and pain than fear avoidance measures alone following whiplash injury. ( 27007066 )
2016
44
A surgical treatment for chronic neck pain after whiplash injury? ( 28850489 )
2016
45
Development of an active behavioural physiotherapy intervention (ABPI) for acute whiplash-associated disorder (WAD) II management: a modified Delphi study. ( 27630069 )
2016
46
Economic and Health-Related Quality of Life Outcomes of Whiplash Associated Disorders. ( 26909831 )
2016
47
The long-term course of deficient cervical kinaesthesia following a whiplash injury has a tendency to seek a physiological homeostasis. A prospective study. ( 26778601 )
2016
48
Predicting nonrecovery among whiplash patients in the emergency room and in an insurance company setting. ( 27405822 )
2016
49
The effect of neck-specific exercise with or without a behavioral approach on psychological factors in chronic whiplash-associated disorders: A randomized controlled trial with a 2-year follow-up. ( 27559950 )
2016
50
Pharmacological and Interventional Management of Pain After Whiplash Injury. ( 27594660 )
2016

Variations for Whiplash

Expression for Whiplash

Search GEO for disease gene expression data for Whiplash.

Pathways for Whiplash

Pathways related to Whiplash according to GeneCards Suite gene sharing:

(show all 14)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.23 CCL3 CCL4 CCL5 CCR5 IL16
2
Show member pathways
13 CCL3 CCL4 CCL5 CCR5 IL16
3
Show member pathways
12.91 CCL3 CCL4 CCL5 CCR5 IL16
4
Show member pathways
12.83 CCL3 CCL4 CCL5 CCR5 IL16
5
Show member pathways
12.49 CCL3 CCL4 CCL5 CCR5
6
Show member pathways
12.46 CCL3 CCL4 CCL5
7
Show member pathways
11.55 CCL3 CCL4 CCR5
8 11.49 CCL3 CCL5
9 11.46 CCL3 CCL4
10
Show member pathways
11.35 CCL3 CCL4 CCL5 CCR5
11 11.23 CCL3 CCL4 CCL5
12
Show member pathways
11.08 CCL3 CCL4
13 10.69 CCL3 CCL4 CCL5 IL16
14 10.61 CCL3 CCL4 CCL5 CCR5

GO Terms for Whiplash

Cellular components related to Whiplash according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 CCL3 CCL4 CCL5 IL16 KNG1
2 extracellular space GO:0005615 9.02 CCL3 CCL4 CCL5 IL16 KNG1

Biological processes related to Whiplash according to GeneCards Suite gene sharing:

(show all 32)
id Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor signaling pathway GO:0007186 9.94 CCL3 CCL4 CCL5 CCR5
2 MAPK cascade GO:0000165 9.8 CCL3 CCL5 CCR5
3 cell-cell signaling GO:0007267 9.8 CCL3 CCL4 CCL5 CCR5
4 immune response GO:0006955 9.8 CCL3 CCL4 CCL5 CCR5 IL16
5 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.79 CCL3 CCL4 CCL5
6 calcium ion transport GO:0006816 9.77 CCL3 CCL5 CCR5
7 cellular response to tumor necrosis factor GO:0071356 9.75 CCL3 CCL4 CCL5
8 inflammatory response GO:0006954 9.72 CCL3 CCL4 CCL5 CCR5 KNG1
9 response to toxic substance GO:0009636 9.71 CCL3 CCL4 CCL5
10 cellular response to interleukin-1 GO:0071347 9.69 CCL3 CCL4 CCL5
11 cellular calcium ion homeostasis GO:0006874 9.65 CCL3 CCL5
12 cellular response to organic cyclic compound GO:0071407 9.65 CCL3 CCL5
13 cell chemotaxis GO:0060326 9.65 CCL3 CCL5
14 neutrophil chemotaxis GO:0030593 9.65 CCL3 CCL4 CCL5
15 calcium-mediated signaling GO:0019722 9.64 CCL3 CCR5
16 positive chemotaxis GO:0050918 9.63 CCL3 CCL5
17 cellular response to interferon-gamma GO:0071346 9.63 CCL3 CCL4 CCL5
18 protein kinase B signaling GO:0043491 9.62 CCL3 CCL5
19 lipopolysaccharide-mediated signaling pathway GO:0031663 9.62 CCL3 CCL5
20 positive regulation of calcium-mediated signaling GO:0050850 9.61 CCL3 CCL4
21 monocyte chemotaxis GO:0002548 9.61 CCL3 CCL4 CCL5
22 dendritic cell chemotaxis GO:0002407 9.6 CCL5 CCR5
23 macrophage chemotaxis GO:0048246 9.58 CCL3 CCL5
24 response to cholesterol GO:0070723 9.57 CCL3 CCR5
25 eosinophil chemotaxis GO:0048245 9.56 CCL3 CCL5
26 signaling GO:0023052 9.55 CCL3 CCR5
27 positive regulation of calcium ion transport GO:0051928 9.54 CCL3 CCL4 CCL5
28 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 9.52 CCL3 CCR5
29 chemokine-mediated signaling pathway GO:0070098 9.46 CCL3 CCL4 CCL5 CCR5
30 negative regulation by host of viral transcription GO:0043922 9.43 CCL3 CCL4 CCL5
31 positive regulation of natural killer cell chemotaxis GO:2000503 9.13 CCL3 CCL4 CCL5
32 chemotaxis GO:0006935 9.02 CCL3 CCL4 CCL5 CCR5 IL16

Molecular functions related to Whiplash according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.46 CCL3 CCL4 CCL5 IL16
2 chemokine activity GO:0008009 9.43 CCL3 CCL4 CCL5
3 chemoattractant activity GO:0042056 9.4 CCL3 CCL5
4 phosphatidylinositol phospholipase C activity GO:0004435 9.37 CCL5 CCR5
5 phospholipase activator activity GO:0016004 9.32 CCL3 CCL5
6 CCR5 chemokine receptor binding GO:0031730 9.13 CCL3 CCL4 CCL5
7 CCR1 chemokine receptor binding GO:0031726 8.8 CCL3 CCL4 CCL5

Sources for Whiplash

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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