MCID: WHP001
MIFTS: 49

Whipple Disease malady

Categories: Rare diseases, Neuronal diseases, Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Whipple Disease

About this section
Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 39MeSH, 40MESH via Orphanet, 45NCIt, 48NIH Rare Diseases, 49NINDS, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Whipple Disease:

Name: Whipple Disease 11 48 54 39 13 68
Intestinal Lipodystrophy 11 48 49 54
Intestinal Lipophagic Granulomatosis 48 54 68
Secondary Non-Tropical Sprue 48 54
 
Whipple's Disease 11 49
Tropheryma Whippelii Infection 48
Whipples Disease 50

Characteristics:

Orphanet epidemiological data:

54
whipple disease:
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe),1-9/1000000 (Italy); Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:8476
ICD1030 K90.81
ICD9CM32 040.2
MeSH39 D008061
NCIt45 C85228
SNOMED-CT62 41545003
Orphanet54 ORPHA3452
ICD10 via Orphanet31 M14.8*, K90.8+
MESH via Orphanet40 C531849, D008061
UMLS via Orphanet69 C0023788, C2930851

Summaries for Whipple Disease

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NINDS:49 Whipple's disease is a multi-system infectious bacterial disease that interferes with the body's ability to metabolize fats. Caused by the bacterium Tropheryma whipplei, the disorder can affect any system in the body, including the brain, eyes, heart, joints, and lungs, but usually occurs in the gastrointestinal system. Neurological symptoms occur in up to 40 percent of individuals and may include dementia, abnormalities of eye and facial muscle movements, headaches, seizures, loss of muscle control, memory loss, weakness, and vision problems. Gastrointestinal symptoms may include diarrhea, weight loss, fatigue, weakness, and abdominal bleeding and pain. Fever, cough, anemia, heart and lung damage, darkening of the skin, and joint soreness may also be present. The disease is more common in men and neurological symptoms are more common in individuals who have severe abdominal disease, Rarely, neurological symptoms may appear without gastrointestinal symptoms and can mimic symptoms of almost any neurologic disease.

MalaCards based summary: Whipple Disease, also known as intestinal lipodystrophy, is related to hypomagnesemia 1, intestinal and apple allergy, and has symptoms including Array, Array and Array. An important gene associated with Whipple Disease is IL16 (Interleukin 16), and among its related pathways are CTLA4 Signaling and Staphylococcus aureus infection. Affiliated tissues include brain, lung and eye.

NIH Rare Diseases:48 Whipple disease is an infectious bacterial disease that affects many different organ systems and interferes with the body's ability to metabolize fats. the disease usually occurs in the gastrointestinal system, but may affect any part of the body including the heart, lungs, brain, joints, and eyes. in the gastrointestinal system, it interferes with the body's ability to absorb certain nutrients. this leads to a condition known as malabsorption. whipple disease causes weight loss, incomplete breakdown of carbohydrates or fats, and malfunctions of the immune system. it is caused by infection from bacteria called tropheryma whipplei (formerly called tropheryma whippelii). when recognized and treated, whipple disease can usually be cured. untreated, the disease may be fatal. last updated: 3/23/2017

Related Diseases for Whipple Disease

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Diseases related to Whipple Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 55)
idRelated DiseaseScoreTop Affiliating Genes
1hypomagnesemia 1, intestinal10.8
2apple allergy10.2HLA-DQB1, HLA-DRB1
3hemoglobin d disease10.2HLA-DQB1, HLA-DRB1
4bilateral parasagittal parieto-occipital polymicrogyria10.2HLA-DQB1, HLA-DRB1
5immune deficiency, familial variable10.2HLA-DQB1, HLA-DRB1
6lin-gettig syndrome10.2HLA-DQB1, HLA-DRB1
7midline interhemispheric variant of holoprosencephaly10.2HLA-DQB1, HLA-DRB1
8autosomal dominant intermediate charcot-marie-tooth10.2HLA-DQB1, HLA-DRB1
9renal agenesis meningomyelocele mullerian defect10.2HLA-DQB1, HLA-DRB1
10lyme disease - neurological complications10.2HLA-DQB1, HLA-DRB1
11distal trisomy 14q10.2HLA-DQB1, HLA-DRB1
12learning disability10.2HLA-DQB1, HLA-DRB1
13linear lichen planus10.2HLA-DQB1, HLA-DRB1
14cervical adenoid basal carcinoma10.2HLA-DQB1, HLA-DRB1
15neonatal antiphospholipid syndrome10.1HLA-DQB1, HLA-DRB1
16clostridium difficile colitis10.1HLA-DQB1, HLA-DRB1
17myofibroma10.1HLA-DQB1, HLA-DRB1
18oromandibular dystonia10.1HLA-DQB1, HLA-DRB1
19bickerstaff brainstem encephalitis10.1HLA-DQB1, HLA-DRB1
20anaerobic meningitis10.1HLA-DQB1, HLA-DRB1
21low anorectal malformation10.1HLA-DQB1, HLA-DRB1
22ragweed sensitivity10.1HLA-DQB1, HLA-DRB1
23pancreatic signet ring cell adenocarcinoma10.1HLA-DRB1, HSPD1
24orofacial granulomatosis10.1CD58, HSPD1
25folinic acid-responsive seizures10.0HLA-DQB1, HLA-DRB1
26basilar artery occlusion10.0HSPD1, MRAP
27lymphangiectasia, intestinal10.0HLA-DQB1, HLA-DRB1
28anterior corneal pigmentation10.0HLA-DQB1, HLA-DRB1
29premature menopause10.0HSPD1, MRAP
30patau syndrome10.0HLA-DRB1, MRAP
31choreatic disease10.0HLA-DQB1, HLA-DRB1
32cryptococcosis9.9HLA-DQB1, HLA-DRB1, MRAP
33parasitic helminthiasis infectious disease9.9HLA-DQB1, HLA-DRB1
34intracranial hemorrhage in brain cerebrovascular malformations9.9HLA-DRB1, HSPD1, MRAP
35pulmonary hypertension9.8
36arthritis9.8
37cerebritis9.8
38uveitis9.7
39cerebellar ataxia9.5
40keratopathy9.5
41thrombosis9.5
42endocarditis9.5
43giardiasis9.5
44spondyloarthropathy9.5
45panuveitis9.5
46posterior uveitis9.5
47diarrhea9.5
48panophthalmitis9.5
49adult-onset still's disease9.5
50prosopagnosia9.5

Graphical network of the top 20 diseases related to Whipple Disease:



Diseases related to whipple disease

Symptoms & Phenotypes for Whipple Disease

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Human phenotypes related to Whipple Disease:

 54 64 (show all 47)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hydrocephalus64 54 Occasional (29-5%) HP:0000238
2 proptosis64 54 Occasional (29-5%) HP:0000520
3 uveitis64 54 Frequent (79-30%) HP:0000554
4 depression64 54 Very frequent (99-80%) HP:0000716
5 hypothyroidism64 54 Occasional (29-5%) HP:0000821
6 insulin resistance64 54 Occasional (29-5%) HP:0000855
7 seizures64 54 Occasional (29-5%) HP:0001250
8 ataxia64 54 Occasional (29-5%) HP:0001251
9 muscle weakness64 54 Occasional (29-5%) HP:0001324
10 myoclonus64 54 Very frequent (99-80%) HP:0001336
11 arthritis64 54 Very frequent (99-80%) HP:0001369
12 myocardial infarction64 54 Occasional (29-5%) HP:0001658
13 pericarditis64 54 Occasional (29-5%) HP:0001701
14 splenomegaly64 54 Frequent (79-30%) HP:0001744
15 anemia64 54 Occasional (29-5%) HP:0001903
16 fever64 54 Very frequent (99-80%) HP:0001945
17 polydipsia64 54 Occasional (29-5%) HP:0001959
18 diarrhea64 54 Very frequent (99-80%) HP:0002014
19 malabsorption64 54 Very frequent (99-80%) HP:0002024
20 abdominal pain64 54 Very frequent (99-80%) HP:0002027
21 anorexia64 54 Very frequent (99-80%) HP:0002039
22 respiratory insufficiency64 54 Occasional (29-5%) HP:0002093
23 pleuritis64 54 Frequent (79-30%) HP:0002102
24 gastrointestinal hemorrhage64 54 Occasional (29-5%) HP:0002239
25 hepatomegaly64 54 Frequent (79-30%) HP:0002240
26 sleep disturbance64 54 Frequent (79-30%) HP:0002360
27 developmental regression64 54 Very frequent (99-80%) HP:0002376
28 encephalitis64 54 Occasional (29-5%) HP:0002383
29 increased intracranial pressure64 54 Occasional (29-5%) HP:0002516
30 hypotension64 54 Frequent (79-30%) HP:0002615
31 arthralgia64 54 Very frequent (99-80%) HP:0002829
32 hyponatremia64 54 Occasional (29-5%) HP:0002902
33 myalgia64 54 Frequent (79-30%) HP:0003326
34 cachexia64 54 Very frequent (99-80%) HP:0004326
35 cranial nerve paralysis64 54 Occasional (29-5%) HP:0006824
36 abnormal pyramidal signs64 54 Occasional (29-5%) HP:0007256
37 generalized hyperpigmentation64 54 Occasional (29-5%) HP:0007440
38 peripheral neuropathy64 54 Occasional (29-5%) HP:0009830
39 edema of the lower limbs64 54 Occasional (29-5%) HP:0010741
40 fatigue64 54 Very frequent (99-80%) HP:0012378
41 cough64 54 Occasional (29-5%) HP:0012735
42 myocarditis64 54 Occasional (29-5%) HP:0012819
43 myositis64 54 Occasional (29-5%) HP:0100614
44 erectile abnormalities64 54 Occasional (29-5%) HP:0100639
45 mediastinal lymphadenopathy64 54 Very frequent (99-80%) HP:0100721
46 chest pain64 54 Occasional (29-5%) HP:0100749
47 galactorrhea64 54 Occasional (29-5%) HP:0100829

Drugs & Therapeutics for Whipple Disease

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Drugs for Whipple Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 74)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Secretinapproved, investigationalPhase 431108153-74-8
Synonyms:
108153-74-8
1393-25-5
67307-60-2 (citrate (salt))
9002-77-1
EINECS 215-733-3
Hormone of the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level
Human secretin
I06-1828
L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-aspartyl-L-seryl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
LS-144747
RG 1068
SECREFLO
SECRETIN
SECRETIN-FERRING
 
SecreFlow
Secrepan
Secretin (human)
Secretin (porcine)
Secretin [INN:BAN:DCF:JAN]
Secretin-Kabi
Secretina
Secretina [INN-Spanish]
Secretine
Secretine [INN-French]
Secretinum
Secretinum [INN-Latin]
Secretolin
UNII-88C55N56UU
UNII-A0426J905J
Vitrum
2
Capecitabineapproved, investigationalPhase 41342154361-50-960953
Synonyms:
(1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester
154361-50-9
158798-73-3
5'-Deoxy-5-fluoro-N-((pentyloxy)carbonyl)cytidine
5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine
AC1L1U83
AC1Q4KU8
Ambap154361-50-9
C110904
C12650
C15H22FN3O6
CAPE
CAPECITABINE
CHEBI:31348
CHEMBL1773
CID60953
Capecitabin
Capecitabina
Capecitabine (JAN/USAN/INN)
Capecitabine [USAN]
Capecitabinum
Capecitibine
Capiibine
Carbamic acid, (1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, pentyl ester
Caxeta
 
D01223
DB01101
FT-0082472
HSDB 7656
LS-59070
MolPort-005-938-254
N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine
Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate
Pentyl [1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate
R-340
R340
RG-340
Ro 09-1978
Ro 09-1978/000
Ro-09-1978
Ro-09-1978/000
S1156_Selleck
UNII-6804DJ8Z9U
Xabine
Xeloda
Xeloda (TN)
Xeloda, Captabin, Capecitabine
ZINC03806413
capecitabina
capecitabine
capecitabinum
pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate
3Hormone AntagonistsPhase 413180
4Gastrointestinal AgentsPhase 4, Phase 28402
5HormonesPhase 414415
6Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 413168
7Antimetabolites, AntineoplasticPhase 4, Phase 27361
8AntimetabolitesPhase 4, Phase 212054
9
EthanolapprovedPhase 3213764-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
10Liver ExtractsPhase 34067
11
PancrelipaseapprovedPhase 297053608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
PA
 
Pancreatic alpha-amylase precursor
Pancrelipase (amylase
lipase
protease)
12
Morphineapproved, investigationalPhase 2100757-27-25288826
Synonyms:
(-)(5.alpha.,6.alpha.)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(-)-Heroin hydrochloride
(-)-Morphine
(-)Morphine sulfate
(5R,6S,9R,13S,14R)-4,5-Epoxy-N-methyl-7-morphinen-3,6-diol
(5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol
(5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(5alpha,6alpha)-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(5α,6α)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
(5α,6α)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL
(7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol
(−)-morphine
17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol
4,5alpha-Epoxy-17-methyl-7-morphinen-3,6alpha-diol
4-methyl-(13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol
47106-99-0
57-27-2
6211-15-0 (sulfate (2:1) (salt) pentahydrate)
64-31-3
64-31-3 (sulfate (2:1) (salt) anhydrous)
7,8-Didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol
7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
8053-16-5
85201-37-2
Apokyn
Astramorph PF
Avinza
BIDD:GT0147
C01516
CCRIS 5762
CHEBI:17303
CHEMBL70
CID5288826
Cube juice
D-(-)-Morphine
DB00295
DEA No. 9300
DepoDur
Depodur
Diacetylmorphine hydrochloride
Diamorphine hydrochloride
Dolcontin
Dreamer
Dulcontin
Duramorph PF
Duromorph
EINECS 200-320-2
Epimorph
HSDB 2134
Hard stuff
Heroin hydrochloride
Heroine hydrochloride
Hocus
 
Infumorph
Kadian
LS-91748
M-Eslon
M.O.S
MOI
MORPHINE SULFATE
MORPHINE, (5A,6A)-7,8-DIDEHYDRO-4,5-EPOXY-17-METHYLMORPHINIAN-3,6-DIOL, MORPHIUM, MORPHIA, DOLCONTIN, DUROMORPH, MORPHINA, NEPENTHE
MS Contin
MS/L
MS/S
MSIR
Meconium
MolPort-003-849-273
Morfina
Morfina [Italian]
Morphia
Morphin
Morphin [German]
Morphina
Morphina [Italian]
Morphine Extra-Forte
Morphine Forte
Morphine H.P
Morphine Sulfate
Morphine [BAN]
Morphinism
Morphinum
Morphitec
Morphium
Morpho
Moscontin
Ms Contin
Ms Emma
NSC11441
Nepenthe
O,O'-Diacetylmorphine hydrochloride
OMS Concentrate
Oramorph SR
Ospalivina
RMS
RMS Uniserts
Rescudose
Roxanol
Roxanol 100
Roxanol UD
SDZ 202-250
SDZ202-250
Statex
Statex Drops
Statex SR
UNII-76I7G6D29C
Unkie
l-Morphine
morfina
morphine
nchembio.317-comp1
nchembio.64-comp1
13
Hydrocortisoneapproved, vet_approvedPhase 266750-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
14
Cortisone acetateapprovedPhase 2691950-04-4, 50-04-45745
Synonyms:
 
Cortisyl
Cortone acetate
15
GemcitabineapprovedPhase 2201895058-81-460750
Synonyms:
103882-84-4
122111-03-9
2',2'-DiF-dC
2',2'-Difluoro-2'-deoxycytidine
2',2'-Difluorodeoxycytidine
2'-Deoxy-.beta.-D-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine
4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one
4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
95058-81-4
AB1004842
AC1L1TUQ
C07650
CCRIS 8984
CHEBI:175901
CHEMBL888
CID60750
Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine
D02368
DB00441
DDFC
DFDC
DFdC
DFdCyd
Folfugem
GEO
Gamcitabine
GemLip
Gemcel
 
Gemcin
Gemcitabin
Gemcitabina
Gemcitabina [INN-Spanish]
Gemcitabine
Gemcitabine (USAN/INN)
Gemcitabine HCl
Gemcitabine hydrochloride
Gemcitabine stereoisomer
Gemcitabinum
Gemcitabinum [INN-Latin]
Gemtro
Gemzar
Gemzar (hydrochloride)
HMS2089P10
HSDB 7567
Inno-D07001
LS-59139
LY 188011
LY-188011
LY188011
NCGC00168784-01
NChemBio.2007.10-comp25
NSC 613327
NSC613327
TL8005979
UNII-B76N6SBZ8R
ZINC18279854
Zefei
gemcitabine
nchembio.573-comp7
nchembio.90-comp2
16
Irinotecanapproved, investigationalPhase 2112397682-44-5, 100286-90-660838
Synonyms:
(+)-Irinotecan
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
(4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-4,12-dihydro-1H-pyrano[3,4-f]quinolino[2,3-a]indolizin-9-yl 4-piperidylpiperidinecarboxylate
1u65
97682-44-5
AC-7469
AC1L1U0Z
AC1Q6PGI
BRD-K08547377-003-02-4
BSPBio_002346
Bio-0054
Biotecan
Biotecan (TN)
C16641
C33H38N4O6
CHEBI:105985
CHEMBL481
CID60838
CP0
Campothecin-11
Campto
Camptosar
 
Camptosar, Campto, CPT-11, Irinotecan
Camptothecin-11
D08086
DB00762
FT-0083650
HSDB 7607
IRINOTECAN HYDROCHLORIDE Trihydrate
IRINOTECAN, CPT-11
Irinotecan (INN)
Irinotecan Hcl
Irinotecan Hydrochloride
Irinotecan Hydrochloride Trihydrate
Irinotecan [INN:BAN]
Irinotecan hydrochloride
Irinotecanum
Irinotecanum [INN-Latin]
LS-44589
NCI60_005051
NSC728073
S1198_Selleck
TL8006026
UNII-7673326042
irinotecan
17
Paclitaxelapproved, vet_approvedPhase 2286433069-62-436314
Synonyms:
(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester
12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
157069-30-2
33069-62-4
5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine
7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.
7-Epi-Paclitaxel
7-Epi-Taxol
7-Epipaclitaxel
7-Epitaxol
7-epi-Paclitaxel
7-epi-Taxol
AB00513812
ABI 007
ABI-007
ABI007
AC-675
AC1L1IOG
AC1L1VJI
AC1L9AVF
ACon1_002231
ANX-513
Abraxane
Abraxane (TN)
Abraxane I.V. Suspension
Abraxis BioScience brand of albumin-bound paclitaxel
Ambotz33069-62-4
Anzatax
Asotax
BIDD:PXR0046
BMS 181339-01
BMS-181339
BMS-181339-01
BPBio1_000320
BRD-A23723433-001-01-2
BRD-A28746609-001-04-0
BRD-K62008436-001-03-1
BSPBio_000290
BSPBio_001152
BSPBio_002614
Bio-0076
Bio1_000362
Bio1_000851
Bio1_001340
Bio2_000416
Bio2_000896
Bristaxol
C07394
C466458
C47H51NO14
CCRIS 8143
CHEBI:103439
CHEBI:45863
CHEMBL100910
CHEMBL418410
CHEMBL48
CID36314
CID441276
CID4666
CID6713921
CID6915727
CPD-8718
Capxol
D00491
DB01229
DHP-107
DHP-208
DRG-0190
DTS-301
DivK1c_000441
EU-0101201
Ebetaxel
EmPAC
Epitaxol
Genaxol
Genetaxyl
Genexol
Genexol-PM
HMS1362J13
HMS1568O12
HMS1792J13
HMS1922K08
HMS1990J13
HMS2090D07
HMS2093K15
HMS501G03
HSDB 6839
I06-0014
IDI1_000441
IDI1_002171
Intaxel
KBio1_000441
KBio2_000492
KBio2_002016
KBio2_002509
KBio2_003060
KBio2_004584
KBio2_005077
KBio2_005628
KBio2_007152
KBio2_007645
KBio3_000903
KBio3_000904
KBio3_001834
KBio3_002987
KBioGR_000492
KBioGR_001893
 
KBioGR_002509
KBioSS_000492
KBioSS_002016
KBioSS_002517
LMPR0104390001
LS-31070
LipoPac
Lopac0_001201
MBT 0206
MEGxp0_001940
MLS000863266
MLS001077297
MLS002154218
MLS002172439
MLS002695976
MPI-5018
Micellar Paclitaxel
Mitotax
MolPort-001-742-627
MolPort-003-665-783
MolPort-003-932-365
NCGC00024995-02
NCGC00024995-03
NCGC00024995-04
NCGC00024995-05
NCGC00024995-06
NCGC00024995-07
NCGC00164367-01
NCGC00164367-02
NCGC00164367-03
NCI60_000601
NINDS_000441
NK 105
NP-010981
NSC 125973
NSC-125973
NSC125973
NSC358882
Nanotaxel
Neuro_000060
Nova-12005
OAS-PAC-100
OncoGel
Onxal
Onxol
Onxol, Taxol, Nov-Onxol, Paclitaxel
P1632
Paclical
Pacligel
Paclitaxel
Paclitaxel (JAN/USP)
Paclitaxel (JAN/USP/INN)
Paclitaxel (Taxol)
Paclitaxel [USAN:INN:BAN]
Paxceed
Paxene
Paxoral
Plaxicel
Praxel
Prestwick0_000155
Prestwick1_000155
Prestwick2_000155
Prestwick3_000155
Probes2_000350
QW 8184
S-8184 Paclitaxel Injectable Emulsion
S1150_Selleck
SDCCGMLS-0066823.P001
SDP-013
SMP1_000228
SMR000394086
SMR000857385
SPBio_000943
SPBio_002229
SPECTRUM1503908
ST50306996
Spectrum2_000872
Spectrum3_001057
Spectrum4_001197
Spectrum5_001491
Spectrum_001536
T 7402
T1912_SIGMA
T7191_SIGMA
T7402_SIGMA
TA1
TAXOL (TN)
TAXOL, 10-EPI,
TXL
TaxAlbin
Taxol
Taxol A
Taxol Konzentrat
Taxol.RTM. (Registered Trademark)
UNII-P88XT4IS4D
UPCMLD-DP108:001
UPCMLD-DP108:002
Vascular Wrap
Xorane
Yewtaxan
abi-007
albumin-bound paclitaxel
cMAP_000068
nab-paclitaxel
nchembio.188-comp1
nchembio.2007.34-comp9
nchembio.215-comp9
nchembio853-comp6
paclitaxel
weekly paclitaxel
18
FluorouracilapprovedPhase 2185651-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen
19
Fentanylapproved, illicit, investigational, vet_approvedPhase 2821437-38-73345
Synonyms:
1-Phenethyl-4-(N-phenylpropionamido)piperidine
1-Phenethyl-4-N-propionylanilinopiperidine
1-phenethyl-4-N-propionylanilinopiperidine
437-38-7
5-22-08-00049 (Beilstein Handbook Reference)
80832-90-2
990-73-8 (citrate)
AC1L1FQ2
Actiq
BIDD:GT0555
BRN 0494484
CHEBI:119915
CHEMBL596
CID3345
D00320
DB00813
Duragesic
Duragesic (TN)
Duragesic-100
Duragesic-12
Duragesic-25
Duragesic-50
Duragesic-75
Durogesic
EINECS 207-113-6
Fentanest
Fentanil
Fentanil [DCIT]
Fentanila
Fentanila [INN-Spanish]
Fentanilo
Fentanyl
Fentanyl (JAN/USAN/INN)
Fentanyl CII
Fentanyl [INN:BAN]
Fentanyl citrate
Fentanyl-100
Fentanyl-12
Fentanyl-25
 
Fentanyl-50
Fentanyl-75
Fentanylum
Fentanylum [INN-Latin]
HSDB 3329
IONSYS
JNS020QD
L001275
LS-124439
Matrifen
MolPort-003-847-369
N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-Phenethyl-4-piperidyl)propionanilide
N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidyl)propionanilide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide
N-Phenethyl-4-(N-propionylanilino)piperidine
N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenethyl-4-(N-propionylanilino)piperidine
N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
NCGC00168252-01
Nasalfent
Oprea1_152073
Oprea1_207148
PDSP1_000860
PDSP2_000846
Pentanyl
Phentanyl
Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)
R 4263
Rapinyl
Sentonil
Sublimase
Sublimaze
UNII-UF599785JZ
fentanyl
20
Butyric AcidexperimentalPhase 2380107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
1-propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
Butyric acid
 
Butyricum acidum
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
N-butanoic acid
N-butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
21Pharmaceutical SolutionsPhase 28192
22pancreatinPhase 2970
23NarcoticsPhase 23646
24Central Nervous System DepressantsPhase 213403
25Anesthetics, IntravenousPhase 22538
26Hydrocortisone 17-butyrate 21-propionatePhase 2667
27Hydrocortisone acetatePhase 2667
28
CortisonePhase 26953-06-5222786
Synonyms:
Andreson
Anusol HC
Balneol-Hc
Colocort
Compound E
Corlin
Cortadren
Cortandren
Cortef
Cortef Acetate
Cortisal
Cortisate
Cortison
Cortisone Acetate
Cortistal
Cortivite
Cortogen
Cortone
Cortril
Dermacort
Dricort
Flexicort
 
Florinef
Fludrocortisone Acetate
Glycort
Hemsol-Hc
Hi-Cor
Incortin
Kendall'S Compound E
Kendall'S compound
Locoid
Locoid Lipocream
Micort-Hc
Nogenic HC
Orabase HCA
Pandel
Prestwick_132
Reichstein Fa
Reichstein'S Substance FA
Scheroson
Solu-Cortef
Stie-Cort
Texacort
Westcort
beta-Hc
29Cortisol succinatePhase 2667
30Anti-Inflammatory AgentsPhase 210729
31Hydrocortisone-17-butyratePhase 2332
32Anesthetics, GeneralPhase 22934
33Peripheral Nervous System AgentsPhase 223689
34Analgesics, OpioidPhase 23238
35AnestheticsPhase 29596
36AnalgesicsPhase 211733
37Anti-Infective AgentsPhase 222062
38Antiviral AgentsPhase 29967
39Immunosuppressive AgentsPhase 213086
40Imatinib MesylatePhase 2600123596
41Protein Kinase InhibitorsPhase 23689
42Topoisomerase InhibitorsPhase 25069
43Antimitotic AgentsPhase 25657
44Antineoplastic Agents, PhytogenicPhase 25602
45Albumin-Bound PaclitaxelPhase 22864
46topoisomerase I inhibitorsPhase 21370
47Adjuvants, AnesthesiaPhase 21674
48KavanutraceuticalPhase 21619000-38-8
49
Octreotideapproved, investigational22383150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
 
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate
50
Somatostatinapproved23738916-34-6, 51110-01-153481605
Synonyms:
growth hormone-inhibiting hormone (GHIH)
 
somatotropin release-inhibiting factor (SRIF)
somatotropin release-inhibiting hormone

Interventional clinical trials:

(show all 46)
idNameStatusNCT IDPhase
1Efficacy of Secretin MRCP in the Diagnosis and Follow up of Auto Immune PancreatitisUnknown statusNCT01845467Phase 4
2Pharmacokinetic Study of Adjuvant Capecitabine After Resection of Pancreatic AdenocarcinomaCompletedNCT00854477Phase 4
3Randomized, Open-Label, Multicenter, Controlled, Pivotal Study to Assess Safety and Efficacy of ELAD in Subjects w/ AILDRecruitingNCT02612428Phase 3
4The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing PancreaticoduodenectomyUnknown statusNCT01428050Phase 2
5Cortisone Treatment for the Prevention of Postoperative Pancreatitis and Pancreatitis-induced Complications After Pancreaticoduodenectomy (Whipple Operation)CompletedNCT01460615Phase 2
6HIPEC as Neoadjuvant Treatment for Resectable Pancreatic AdenocarcinomaRecruitingNCT02850874Phase 2
7Allogeneic Hematopoietic Stem Cell Transplantation in Pancreatic AdenocarcinomaRecruitingNCT02207985Phase 1, Phase 2
8Surgery for Locally Unresectable Advanced GISTs Without Metastasis After Imatinib TherapyRecruitingNCT01865565Phase 2
9Phase 2 Evaluation of Multi-modality Algorithm for Non-metastatic Adenocarcinoma of Pancreas or AmpullaActive, not recruitingNCT02626520Phase 2
10Imaging of periOP Lung InjuryNot yet recruitingNCT02978885Phase 2
11Study to Explore Effectiveness of Sublingual Fentanyl Spray in Emergency Department Patients With Acute PainNot yet recruitingNCT02137525Phase 2
12The Size of the Gastric Remnant as Determinant for Delayed Gastric Emptying After Whipple Resection.TerminatedNCT02041052Phase 2
13Preoperative Stent StudyUnknown statusNCT00501176
14Comparison Between Endoscopic Stenting and Cholecystojejunostomy for PreoperativeDrainage Before PancreaticoduodenectomyUnknown statusNCT01913275
15Etiology, Assessment and Treatment of Post-gastric Bypass Severe HypoglycemiaUnknown statusNCT01865760
16Anastomotic Techniques in PancreaticoduodenectomyUnknown statusNCT00855985
17Effect of Chewing Gum on Postoperative Bowel Function Following Upper GI Tract Cancer SurgeryUnknown statusNCT02260128
18Mesenteric Traction Syndrome During Upper Gastrointestinal SurgeryCompletedNCT02507414
19The Prognostic Impact of Extracapsular Lymph Node Involvement in Ductal Pancreatic AdenocarcinomaCompletedNCT00644254
20Economisation of Whipple Resection Using an Ultrasonic Dissection DeviceCompletedNCT01321450
21Gastric Emptying After Infracolic or Supracolic Gastrojejunostomy Following PancreaticoduodenectomyCompletedNCT01191138
22Pancreatic Resection, Malnutrition and ReadmissionCompletedNCT01947166
23Reconstruction Following Pancreaticoduodenectomy: A Randomized Clinical Trial of Pancreaticojejunostomy vs PancreaticogastomyCompletedNCT00841607
24Abdominal Exploration Without IncisionsCompletedNCT00427752Early Phase 1
25Reconstruction Method and Delayed Gastric Emptying After Pancreatic SurgeryCompletedNCT01248663
26A Comparison Study Between Ketamine Versus Tramadol for Pain Management After Major Upper Abdominal SurgeryCompletedNCT02499341
27Chronic Infection With Tropheryma Whipplei: Risk Factors Related to the HostRecruitingNCT02868450
28Whipple Procedure: Standard of Care vs. ThunderbeatRecruitingNCT02204124
29GI Neuromuscular Pathology Prospective RegistryRecruitingNCT02165059
30Patient Centered Home Exercise Program for Peripheral Artery DiseaseRecruitingNCT02462824
31The PASTEC Study: Endoscopic Stenting Versus Surgery for the Treatment of Bile Duct Stricture in Chronic PancreatitisRecruitingNCT02366988
32Registry Study - Whipple at the Splenic ArteryRecruitingNCT01155882
33The Use of Wound Protector in Whipple's Procedure With Intrabiliary StentRecruitingNCT01836237
34Accelerated Recovery Pathway for Discharge After Surgery in Patients With Pancreatic CancerRecruitingNCT02517268
35EVIS - Ex-vivo Assessment of T-lymphocyte Homing in Primary Pancreatic CancerRecruitingNCT02695966
36Yttrium Y 90 Resin Microspheres Data Collection in Unresectable Liver Cancer: the RESIN StudyRecruitingNCT02685631
37Endoscopic Ultrasound Guided Radiofrequency Ablation (EUS-RFA) for Small Benign Pancreatic TumorsRecruitingNCT02882503
38Study of Intratumoral Hypoxia Using Pre-operative Administration of PimonidazoleRecruitingNCT01248637
39Neuroform Atlas IDE StudyRecruitingNCT02340585
40Outcomes in Minimally Invasive Versus Open PancreaticoduodenectomyEnrolling by invitationNCT02638818
41Clinical Trial of Pancreatic Cancer in Stockholm.Enrolling by invitationNCT02162823
42The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal SurgeryEnrolling by invitationNCT02381249
43The Effect of a Local Injection of a Platelet Concentrate on Infection and Healing of Surgical WoundsNot yet recruitingNCT02869204
44Trial of Omental Roll-up Technique on Pancreato-jejunostomy Anastomosis for Reducing Perioperative Complication in Patients Undergoing PancreatoduodenectomyNot yet recruitingNCT03083938
45Initial Feasibility Study to Treat Pancreatic Cancer With a Planar LDR SourceNot yet recruitingNCT02843945
46Initial Feasibility Study to Treat Resectable Pancreatic Cancer With a Planar LDR SourceNot yet recruitingNCT03109041

Search NIH Clinical Center for Whipple Disease


Cochrane evidence based reviews: whipple disease

Genetic Tests for Whipple Disease

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Anatomical Context for Whipple Disease

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MalaCards organs/tissues related to Whipple Disease:

36
Brain, Lung, Eye, Heart, Skin, Spinal cord, B cells

Publications for Whipple Disease

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Articles related to Whipple Disease:

(show top 50)    (show all 104)
idTitleAuthorsYear
1
Ultrastructural changes of small intestine in Whipple disease patient. (28230475)
2017
2
Genotypic analysis of Tropheryma whipplei from patients with Whipple disease in the Americas. (28385924)
2017
3
Pseudo-Whipple Disease Cutaneous Lesions. (27097339)
2016
4
Deep Vein Thrombosis as Initial Manifestation of Whipple Disease. (27920655)
2016
5
Prosopagnosia as the Presenting Symptom of Whipple Disease. (27336807)
2016
6
Whipple disease confined to the central nervous system presenting as a cystic tumor: Case report and review of literature. (27593833)
2016
7
Gastrointestinal diagnosis of classical whipple disease: clinical, endoscopic, and histopathologic features in 191 patients. (25881849)
2015
8
Primary Whipple disease of the brain: case report with long-term clinical and MRI follow-up. (26445540)
2015
9
Atypical presentation of Whipple disease with no diarrhea. (26275278)
2015
10
Pulmonary hypertension associated with Whipple disease. (25445953)
2014
11
Specific cutaneous involvement in Whipple disease. (24562051)
2014
12
Neurocognitive impairment in Whipple disease with central nervous system involvement. (24674966)
2014
13
Bilateral panuveitis associated with Whipple disease - case report. (27625936)
2014
14
Resolution of Whipple Disease-Induced Pulmonary Hypertension Following Antibiotic Therapy. (23344104)
2013
15
Monoclonal B-cell lymphocyte proliferation in a patient presenting with historical Whipple disease. (23441662)
2013
16
Whipple disease diagnosed with PCR using formalin-fixed paraffin-embedded specimens of the intestinal mucosa. (23318851)
2013
17
A severe Whipple disease with an immune reconstitution inflammatory syndrome: An additional case of thalidomide efficiency. (24289960)
2013
18
Oculomasticatory myorhythmia and agrypnia excitata guide the diagnosis of Whipple disease. (24210608)
2013
19
Rheumatic and musculoskeletal features of Whipple disease: a report of 29 cases. (24187107)
2013
20
Central nervous system involvement in Whipple disease: clinical study of 18 patients and long-term follow-up. (24145700)
2013
21
Whipple disease revealed by lung involvement: a case report and literature review. (22670021)
2012
22
Whipple disease with crystalline keratopathy and chronic uveitis. (22965603)
2012
23
Isolated CNS Whipple disease with normal brain MRI and false-positive CSF 14-3-3 protein: a case report and review of the literature. (23170246)
2012
24
Whipple disease mimicking adult-onset Still's disease and treated by anakinra: diagnosis using PCR. (22639877)
2012
25
Treated Whipple disease with erythema nodosum leprosum-like lesions: cutaneous PAS-positive macrophages slowly decrease with time and are associated with lymphangiectases: a case report. (22123268)
2012
26
Whipple disease a century after the initial description: increased recognition of unusual presentations, autoimmune comorbidities, and therapy effects. (22743287)
2012
27
Peripheral neuropathy in Whipples disease: a case report. (22716061)
2012
28
Connecting the dots: the many systemic manifestations of whipple disease. (22347837)
2012
29
A unique posterior segment manifestation of whipple disease. (25390964)
2012
30
Whipple disease research accelerates. (21628651)
2011
31
Intestinal Mycobacterium avium complex infection initially misdiagnosed and mistreated as Whipple disease. (20138615)
2010
32
The immune reconstitution inflammatory syndrome in whipple disease: a cohort study. (21135294)
2010
33
Whipple disease. (20224490)
2010
34
Infection: How should classic Whipple disease be managed? (20442732)
2010
35
Whipple disease of the central nervous system: an unusual occurrence in association with acquired immune deficiency syndrome. (19612977)
2010
36
MR imaging of central nervous system Whipple disease: a 15-year review. (20395395)
2010
37
The amnesic syndrome of primary Whipple disease of the brain. (20299864)
2010
38
A paradoxical Tropheryma whipplei western blot differentiates patients with whipple disease from asymptomatic carriers. (19635029)
2009
39
Renal amyloidosis in Whipple disease: a case report. (19918433)
2009
40
Whipple disease: unusual presentation of a protean and sometimes confusing disease. (18538828)
2009
41
Isolated Whipple disease of the brain resembling a tumour. (19194653)
2009
42
Reversible pulmonary hypertension in Whipple disease: a case report with clinicopathological implications, and literature review. (21686934)
2009
43
Postoperative panophthalmitis caused by Whipple disease. (19402983)
2009
44
Primary cerebral Whipple disease presenting as KlA1ver-Bucy syndrome. (19139312)
2009
45
Exacerbation of Whipple disease by immunosuppressants. (18496383)
2008
46
Whipple disease. (18301263)
2008
47
Value of Tropheryma whipplei quantitative polymerase chain reaction assay for the diagnosis of Whipple disease: usefulness of saliva and stool specimens for first-line screening. (18662136)
2008
48
Recurrent orbital inflammation and Whipple disease. (18379941)
2008
49
Neurologically presenting Whipple disease: case report and review of the literature. (18381382)
2008
50
Acquired resistance to trimethoprim-sulfamethoxazole during Whipple disease and expression of the causative target gene. (18500934)
2008

Variations for Whipple Disease

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Expression for genes affiliated with Whipple Disease

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Search GEO for disease gene expression data for Whipple Disease.

Pathways for genes affiliated with Whipple Disease

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Pathways related to Whipple Disease according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.6HLA-DQB1, HLA-DRB1
29.6HLA-DQB1, HLA-DRB1
39.2CD58, HLA-DQB1, HLA-DRB1
49.2CD58, HLA-DQB1, HLA-DRB1
59.1HLA-DQB1, HLA-DRB1, HSPD1

GO Terms for genes affiliated with Whipple Disease

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Cellular components related to Whipple Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1clathrin-coated endocytic vesicle membraneGO:003066910.2HLA-DQB1, HLA-DRB1
2endocytic vesicle membraneGO:003066610.2HLA-DQB1, HLA-DRB1
3ER to Golgi transport vesicle membraneGO:001250710.1HLA-DQB1, HLA-DRB1
4integral component of lumenal side of endoplasmic reticulum membraneGO:007155610.1HLA-DQB1, HLA-DRB1
5MHC class II protein complexGO:004261310.1HLA-DQB1, HLA-DRB1
6transport vesicle membraneGO:00306589.6HLA-DQB1, HLA-DRB1

Biological processes related to Whipple Disease according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1antigen processing and presentationGO:001988210.3HLA-DQB1, HLA-DRB1
2antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIGO:000250410.3HLA-DQB1, HLA-DRB1
3humoral immune response mediated by circulating immunoglobulinGO:000245510.3HLA-DQB1, HLA-DRB1
4immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.3HLA-DQB1, HLA-DRB1
5interferon-gamma-mediated signaling pathwayGO:006033310.3HLA-DQB1, HLA-DRB1
6T cell costimulationGO:003129510.3HLA-DQB1, HLA-DRB1
7inositol biosynthetic processGO:00060219.8IMPA2, ISYNA1
8inositol phosphate metabolic processGO:00436479.8IMPA2, ISYNA1
9viral processGO:00160329.2HLA-DRB1, HSPD1, IL16

Molecular functions related to Whipple Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:003239510.0HLA-DQB1, HLA-DRB1
2peptide antigen bindingGO:00426059.6HLA-DQB1, HLA-DRB1

Sources for Whipple Disease

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet