MCID: WLM005
MIFTS: 20

Wilms Tumor 2 malady

Nephrological, Cancer categories

Summaries for Wilms Tumor 2

Sources:
47OMIM, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Wilms Tumor 2, also known as nephroblastoma, is related to wilms tumor and beckwith-wiedemann syndrome. An important gene associated with Wilms Tumor 2 is WT2 (Wilms tumor 2). Affiliated tissues include kidney and breast.

Description from OMIM:47 194071

Aliases & Classifications for Wilms Tumor 2

Sources:
61UMLS, 47OMIM
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Nephrological


Aliases & Descriptions:

wilms tumor 2 47
nephroblastoma 61


Related Diseases for Wilms Tumor 2

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the wilms tumor, type 1 family:

wilms tumor familial wilms tumor 2
familial wilms tumor wilms tumor 2
wilms tumor, type 3 wilms tumor, type 4

Diseases related to Wilms Tumor 2 via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 65)
idRelated DiseaseScoreTop Affiliating Genes
1wilms tumor31.1WT2, H19
2beckwith-wiedemann syndrome29.8RSS, H19
3n syndrome10.4
4familial wilms tumor 210.3
5cystic nephroma10.2
6aniridia10.2
7renal wilms' tumor10.1
8hypercalcemia10.1
9testicular germ cell tumor10.1
10teratoma10.1
11hereditary wilms' tumor10.0
12fanconi's anemia10.0
13adrenal neuroblastoma10.0
14metanephric adenoma10.0
15denys-drash syndrome10.0
16adenoma10.0
17horseshoe kidney10.0
18wilms tumor, type 110.0
19nephritis10.0
20mesoblastic nephroma10.0
21renal dysplasia10.0
22silver-russell syndrome10.0RSS, H19
23neurofibromatosis9.9
24wagr syndrome9.9
25cervical wilms' tumor9.9
26blastoma9.9
27bone carcinoma9.9
28cloacogenic carcinoma9.9
29osteonecrosis9.9
30papillary carcinoma9.9
31xanthogranulomatous pyelonephritis9.9
32osteopetrosis9.9
33papillary renal cell carcinoma9.9
34hydronephrosis9.9
35liver inflammatory pseudotumor9.9
36alveolar rhabdomyosarcoma9.9
37childhood multilocular cystic kidney neoplasm9.9
38fanconi syndrome9.9
39ovarian wilms' cancer9.9
40portal hypertension9.9
41alagille syndrome9.9
42clear cell sarcoma9.9
43malignant cystic nephroma9.9
44protein c deficiency9.9
45small cell sarcoma9.9
46acute leukemia9.9
47papillary adenoma9.9
48micro syndrome9.9
492q37 microdeletion syndrome9.9
50simpson-golabi-behmel syndrome type 19.9

Graphical network of the top 20 diseases related to Wilms Tumor 2:



Diseases related to wilms tumor 2

Clinical Features for Wilms Tumor 2

Sources:
47OMIM
See all sources

Clinical features from OMIM:

194071

Clinical synopsis from OMIM:

194071

Drugs & Therapeutics for Wilms Tumor 2

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Wilms Tumor 2

Drug clinical trials:

Search ClinicalTrials for Wilms Tumor 2

Search NIH Clinical Center for Wilms Tumor 2

Search CenterWatch for Wilms Tumor 2

Genetic Tests for Wilms Tumor 2

Anatomical Context for Wilms Tumor 2

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Wilms Tumor 2:

33
Kidney, Breast

Animal Models for Wilms Tumor 2 or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Wilms Tumor 2

Sources:
51PubMed
See all sources

Articles related to Wilms Tumor 2:

idTitleAuthorsYear
1
Development of breast cancer in a 21-year-old childhood Wilms' tumor survivor with a BRCA1 2634delC mutation. (21729660)
2011
2
A unique presentation of 22q13 deletion syndrome: multicystic kidney, orofacial clefting, and Wilms' tumor. (20827177)
2011
3
Wilms tumor in a patient with 22q11.2 microdeletion. (21456030)
2011
4
Loss of heterozygosity at 2q37 in sporadic Wilms' tumor: putative role for miR-562. (19789318)
2009
5
Wilms' tumor and gonadal dysgenesis in a child with the 2q37.1 deletion syndrome. (9650765)
1998

Genetic Variations for Wilms Tumor 2

Expression for genes affiliated with Wilms Tumor 2

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Wilms Tumor 2

Search GEO for disease gene expression data for Wilms Tumor 2.

Pathways for genes affiliated with Wilms Tumor 2

Compounds for genes affiliated with Wilms Tumor 2

GO Terms for genes affiliated with Wilms Tumor 2

Products for genes affiliated with Wilms Tumor 2

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Wilms Tumor 2

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet