MCID: WLM004
MIFTS: 14

Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome malady

Cancer diseases category

Summaries for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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MalaCards: Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome, also known as wagr syndrome, is related to wagr syndrome and aniridia. An important gene associated with Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome is WT1 (Wilms tumor 1). The compound proline have been mentioned in the context of this disorder.

Aliases & Classifications for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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60UMLS, 20GeneTests
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

wilms tumor-aniridia-genital anomalies-retardation syndrome 20
wagr syndrome 60


Related Diseases for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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17GeneCards, 18GeneDecks
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Diseases related to Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 21)
idRelated DiseaseScoreTop Affiliating Genes
1wagr syndrome30.7WT1, PAX6
2aniridia30.4WT1, PAX6
3obesity10.4
4polydactyly10.2
5crohn's disease10.0
6focal segmental glomerulosclerosis10.0
7succinic semialdehyde dehydrogenase deficiency10.0
8hypospadias10.0
9tetralogy of fallot10.0
10morbid obesity10.0
11down syndrome10.0
12focal glomerulosclerosis10.0
13congenital diaphragmatic hernia10.0
14hydrocephalus10.0
15pancreatitis10.0
16peters plus syndrome10.0PAX6
17medulloblastoma10.0PAX6
18intellectual disability10.0PAX6
19cataract10.0PAX6
20nephroblastoma10.0WT1, PAX6
21wilms tumor10.0WT1, PAX6

Graphical network of the top 20 diseases related to Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome:



Diseases related to wilms tumor-aniridia-genital anomalies-retardation syndrome

Clinical Features for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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Drugs & Therapeutics for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

Search CenterWatch for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

Genetic Tests for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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20GeneTests
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Genetic tests related to Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome:

id Genetic test Affiliating Genes
1 Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome20 WT1

Anatomical Context for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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Animal Models for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome or affiliated genes

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Publications for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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Genetic Variations for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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Expression for genes affiliated with Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

Search GEO for disease gene expression data for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome.

Pathways for genes affiliated with Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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Compounds for genes affiliated with Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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44Novoseek
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Compounds related to Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1proline449.3PAX6, WT1

GO Terms for genes affiliated with Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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16Gene Ontology
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Biological processes related to Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of transcription, DNA-dependentGO:0458939.3PAX6, WT1

Products for genes affiliated with Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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  • Antibodies
  • Proteins
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  • Antibodies

Sources for Wilms Tumor-Aniridia-Genital Anomalies-Retardation Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet