MCID: WLF009
MIFTS: 15

Wolfram Syndrome 2 malady

Summaries for Wolfram Syndrome 2

Sources:
47OMIM, 33MalaCards
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MalaCards: Wolfram Syndrome 2 is related to wolfram syndrome and diabetes insipidus. An important gene associated with Wolfram Syndrome 2 is CISD2 (CDGSH iron sulfur domain 2).

Description from OMIM:47 604928

Aliases & Classifications for Wolfram Syndrome 2

Sources:
20GeneTests, 22GTR, 47OMIM, 61UMLS
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Aliases & Descriptions:

wolfram syndrome 2 20 22 47 61


Related Diseases for Wolfram Syndrome 2

Sources:
17GeneCards, 18GeneDecks
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Diseases in the wolfram syndrome family:

wolfram syndrome 2 wolfram syndrome-like disease

Diseases related to Wolfram Syndrome 2 via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1wolfram syndrome30.6WFS1, CISD2
2diabetes insipidus10.0WFS1
3opa3-related 3-methylglutaconic aciduria10.0WFS1, CISD2
4waterhouse-friderichsen syndrome10.0WFS1, CISD2

Clinical Features for Wolfram Syndrome 2

Sources:
47OMIM
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Clinical features from OMIM:

604928

Drugs & Therapeutics for Wolfram Syndrome 2

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Wolfram Syndrome 2

Drug clinical trials:

Search ClinicalTrials for Wolfram Syndrome 2

Search NIH Clinical Center for Wolfram Syndrome 2

Search CenterWatch for Wolfram Syndrome 2

Genetic Tests for Wolfram Syndrome 2

Sources:
20GeneTests, 22GTR
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Genetic tests related to Wolfram Syndrome 2:

id Genetic test Affiliating Genes
1 Wolfram Syndrome 220 22 CISD2

Anatomical Context for Wolfram Syndrome 2

Animal Models for Wolfram Syndrome 2 or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Wolfram Syndrome 2

Sources:
51PubMed
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Articles related to Wolfram Syndrome 2:

idTitleAuthorsYear
1
Deletion of mitochondrial DNA in a case of early-onset diabetes mellitus, optic atrophy, and deafness (Wolfram syndrome, MIM 222300). (8383698)
1993

Genetic Variations for Wolfram Syndrome 2

Expression for genes affiliated with Wolfram Syndrome 2

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Wolfram Syndrome 2

Search GEO for disease gene expression data for Wolfram Syndrome 2.

Pathways for genes affiliated with Wolfram Syndrome 2

Compounds for genes affiliated with Wolfram Syndrome 2

GO Terms for genes affiliated with Wolfram Syndrome 2

Sources:
16Gene Ontology
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Cellular components related to Wolfram Syndrome 2 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial outer membraneGO:0057419.4CISD2, CISD1

Molecular functions related to Wolfram Syndrome 2 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
12 iron, 2 sulfur cluster bindingGO:0515379.4CISD2, CISD1

Products for genes affiliated with Wolfram Syndrome 2

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Wolfram Syndrome 2

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet