MCID: WLF009
MIFTS: 16

Wolfram Syndrome 2 malady

Summaries for Wolfram Syndrome 2

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Sources:
46OMIM, 32MalaCards
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MalaCards: Wolfram Syndrome 2 is related to wolfram syndrome and diabetes insipidus. An important gene associated with Wolfram Syndrome 2 is CISD2 (CDGSH iron sulfur domain 2).

Description from OMIM:46 604928

Aliases & Classifications for Wolfram Syndrome 2

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Sources:
20GeneTests, 22GTR, 46OMIM, 60UMLS
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Aliases & Descriptions:

wolfram syndrome 2 20 22 46 60


Related Diseases for Wolfram Syndrome 2

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Wolfram Syndrome family:

wolfram syndrome 2 Wolfram Syndrome-Like Disease

Diseases related to Wolfram Syndrome 2 via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1wolfram syndrome30.6WFS1, CISD2
2diabetes insipidus10.0WFS1
3opa3-related 3-methylglutaconic aciduria10.0WFS1, CISD2
4waterhouse-friderichsen syndrome10.0WFS1, CISD2

Clinical Features for Wolfram Syndrome 2

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Sources:
46OMIM
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Clinical features from OMIM:

604928

Drugs & Therapeutics for Wolfram Syndrome 2

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Wolfram Syndrome 2

Drug clinical trials:

Search ClinicalTrials for Wolfram Syndrome 2

Search NIH Clinical Center for Wolfram Syndrome 2

Search CenterWatch for Wolfram Syndrome 2

Genetic Tests for Wolfram Syndrome 2

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20GeneTests, 22GTR
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Genetic tests related to Wolfram Syndrome 2:

id Genetic test Affiliating Genes
1 Wolfram Syndrome 220 22 CISD2

Anatomical Context for Wolfram Syndrome 2

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Animal Models for Wolfram Syndrome 2 or affiliated genes

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Publications for Wolfram Syndrome 2

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Genetic Variations for Wolfram Syndrome 2

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Expression for genes affiliated with Wolfram Syndrome 2

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Wolfram Syndrome 2

Search GEO for disease gene expression data for Wolfram Syndrome 2.

Pathways for genes affiliated with Wolfram Syndrome 2

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Compounds for genes affiliated with Wolfram Syndrome 2

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GO Terms for genes affiliated with Wolfram Syndrome 2

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Sources:
16Gene Ontology
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Cellular components related to Wolfram Syndrome 2 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial outer membraneGO:0057419.4CISD2, CISD1

Molecular functions related to Wolfram Syndrome 2 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
12 iron, 2 sulfur cluster bindingGO:0515379.4CISD2, CISD1

Products for genes affiliated with Wolfram Syndrome 2

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Wolfram Syndrome 2

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet