MCID: WLF010
MIFTS: 13

Wolfram Syndrome-Like Disease malady

Categories: Genetic diseases, Rare diseases, Eye diseases, Ear diseases, Endocrine diseases, Fetal diseases

Aliases & Classifications for Wolfram Syndrome-Like Disease

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Aliases & Descriptions for Wolfram Syndrome-Like Disease:

Name: Wolfram Syndrome-Like Disease 24
 
Wolfram-Like Syndrome 24 27

Classifications:



Summaries for Wolfram Syndrome-Like Disease

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MalaCards based summary: Wolfram Syndrome-Like Disease, also known as wolfram-like syndrome, is related to wolfram-like syndrome, autosomal dominant, and has symptoms including male hypogonadism, abnormality of the pinna and glaucoma. An important gene associated with Wolfram Syndrome-Like Disease is WFS1 (Wolframin ER Transmembrane Glycoprotein).

Related Diseases for Wolfram Syndrome-Like Disease

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Diseases in the Wolfram Syndrome family:

Wolfram-Like Syndrome, Autosomal Dominant Wolfram Syndrome 2
wolfram syndrome-like disease

Diseases related to Wolfram Syndrome-Like Disease via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1wolfram-like syndrome, autosomal dominant12.4

Symptoms & Phenotypes for Wolfram Syndrome-Like Disease

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Human phenotypes related to Wolfram Syndrome-Like Disease:

 64 (show all 22)
id Description HPO Frequency HPO Source Accession
1 male hypogonadism64 HP:0000026
2 abnormality of the pinna64 HP:0000377
3 glaucoma64 HP:0000501
4 optic atrophy64 HP:0000648
5 psychosis64 HP:0000709
6 depression64 HP:0000716
7 dementia64 HP:0000726
8 autistic behavior64 HP:0000729
9 anxiety64 HP:0000739
10 diabetes mellitus64 HP:0000819
11 hypothyroidism64 HP:0000821
12 delayed puberty64 HP:0000823
13 glucose intolerance64 HP:0000833
14 central diabetes insipidus64 HP:0000863
15 progressive cerebellar ataxia64 HP:0002073
16 respiratory insufficiency64 HP:0002093
17 gastrointestinal dysmotility64 HP:0002579
18 peripheral axonal neuropathy64 HP:0003477
19 primary gonadal insufficiency64 HP:0008193
20 congenital sensorineural hearing impairment64 HP:0008527
21 severe postnatal growth retardation64 HP:0008850
22 abnormality of the upper urinary tract64 HP:0010935

Drugs & Therapeutics for Wolfram Syndrome-Like Disease

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Wolfram Syndrome-Like Disease

Genetic Tests for Wolfram Syndrome-Like Disease

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Genetic tests related to Wolfram Syndrome-Like Disease:

id Genetic test Affiliating Genes
1 Wolfram Syndrome-Like Disease27 24 WFS1

Anatomical Context for Wolfram Syndrome-Like Disease

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Publications for Wolfram Syndrome-Like Disease

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Variations for Wolfram Syndrome-Like Disease

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Expression for genes affiliated with Wolfram Syndrome-Like Disease

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Search GEO for disease gene expression data for Wolfram Syndrome-Like Disease.

Pathways for genes affiliated with Wolfram Syndrome-Like Disease

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GO Terms for genes affiliated with Wolfram Syndrome-Like Disease

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Sources for Wolfram Syndrome-Like Disease

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet