X-linked Leigh Syndrome malady

MalaCards: X-linked Leigh Syndrome, also known as leigh syndrome, x-linked, is related to leigh disease and leigh syndrome due to mitochondrial complex i deficiency. An important gene associated with X-linked Leigh Syndrome is PDHA1 (pyruvate dehydrogenase (lipoamide) alpha 1).

OMIM: 308930

x-linked leigh syndrome 16 leigh syndrome, x-linked 33 43

leigh disease 43

Diseases related to x-linked leigh syndrome by text searches and GeneDecks gene sharing:

(show all 13)

id	Related Disease	Score	Top Affiliating Genes
1	leigh disease	9.8
2	leigh syndrome due to mitochondrial complex i deficiency	5.9
3	leigh syndrome, due to cox deficiency	5.9
4	mitochondrial dna-associated leigh syndrome and narp	5.9
5	maternally inherited leigh syndrome	5.9
6	neuropathy	5.9
7	peripheral neuropathy	5.9
8	3-methylglutaconic aciduria	5.9
9	leigh syndrome due to cytochrome c oxidase deficiency	5.9
10	leigh syndrome, french canadian type	5.9
11	leigh syndrome (mtdna deletion)	5.9
12	leigh syndrome (mtdna mutation)	5.9
13	leigh syndrome (nuclear dna mutation)	5.9

Clinical features from OMIM: 308930

Approved drugs:

Drug clinical trials:

Genetic tests related to x-linked leigh syndrome:

id	Genetic test	Affiliating Genes
1	X-linked Leigh Syndrome clinical/research	PDHA1

Genes related to x-linked leigh syndrome according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	11.1	Disorders, Summaries