MCID: XNT001
MIFTS: 32

Xanthogranulomatous Pyelonephritis

Categories: Nephrological diseases

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

MalaCards integrated aliases for Xanthogranulomatous Pyelonephritis:

Name: Xanthogranulomatous Pyelonephritis 12 14
Pyelonephritis, Xanthogranulomatous 41 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11401
MeSH 41 D011705
NCIt 46 C123038
SNOMED-CT 64 197777006 38898003
UMLS 69 C0034188

Summaries for Xanthogranulomatous Pyelonephritis

MalaCards based summary : Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to renal tuberculosis and autosomal dominant polycystic kidney disease. An important gene associated with Xanthogranulomatous Pyelonephritis is CCL2 (C-C Motif Chemokine Ligand 2), and among its related pathways/superpathways are Immune response_Oncostatin M signaling via JAK-Stat in human cells and LDL Oxidation in Atherogenesis. Affiliated tissues include kidney, lung and liver, and related phenotype is immune system.

Related Diseases for Xanthogranulomatous Pyelonephritis

Diseases related to Xanthogranulomatous Pyelonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 123)
# Related Disease Score Top Affiliating Genes
1 renal tuberculosis 30.3 CRP LYZ NCF4 PKDREJ
2 autosomal dominant polycystic kidney disease 30.2 CCL2 EGF PKDREJ
3 diverticulitis 30.2 CRP PKDREJ
4 pyelonephritis 11.2
5 endometrial adenosquamous carcinoma 10.6 EGF SERPINA3
6 heel spur 10.5 CRP HCCS
7 erdheim-chester disease 10.5 CCL2 SERPINA3
8 ovarian squamous cell carcinoma 10.5 CRP SMUG1
9 urogenital tuberculosis 10.5 NCF4 PKDREJ
10 tricuspid valve prolapse 10.5 EGF PKDREJ
11 pyuria 10.5 CRP NUMA1
12 aortitis 10.5 CRP SMUG1
13 acute maxillary sinusitis 10.5 CRP HCCS
14 breast cyst 10.4 EGF SERPINA3
15 cartilage disease 10.4 CRP SMUG1
16 dermis tumor 10.4 LYZ SERPINA3
17 blue toe syndrome 10.4 CRP LYZ
18 acute proliferative glomerulonephritis 10.4 CCL2 LYZ
19 cutaneous solitary mastocytoma 10.4 LYZ SERPINA3
20 central nervous system vasculitis 10.4 CRP SMUG1
21 renal cell carcinoma, nonpapillary 10.4
22 tuberculous peritonitis 10.4 CRP SMUG1
23 urinary tract obstruction 10.4 CCL2 EGF PKDREJ
24 laryngeal tuberculosis 10.4 LYZ SMUG1
25 lemierre's syndrome 10.4 CRP SMUG1
26 pulmonary aspergilloma 10.3 CRP NUMA1 SMUG1
27 chronic pyelonephritis 10.3 CPN1 PKDREJ
28 verruciform xanthoma of skin 10.3 CCL2 CD68
29 meningitis 10.3 CCL2 CRP LYZ
30 ischemic heart disease 10.3 CCL2 CRP
31 pancreatic cystadenocarcinoma 10.3 PKDREJ SERPINA3
32 amyloidosis 10.3
33 nodular tenosynovitis 10.3 CD68 SERPINA3
34 endocervicitis 10.3 CCL2 CD68
35 retinal hemangioblastoma 10.2 LYZ PKDREJ SERPINA3
36 lipomatosis 10.2
37 inflammatory mfh 10.2 CD68 SERPINA3
38 pulmonary artery leiomyosarcoma 10.2 CD68 SMUG1
39 sternum cancer 10.2 CD68 SMUG1
40 hepatitis 10.2
41 malakoplakia 10.2
42 pericoronitis 10.2 CD68 CRP
43 non-secretory myeloma 10.2 ITGAX SMUG1
44 brain sarcoma 10.2 CD68 SMUG1
45 central nervous system sarcoma 10.2 CD68 LYZ
46 temporal arteritis 10.2 CCL2 CRP SERPINA3 SMUG1
47 malignant giant cell tumor of soft parts 10.2 CD68 LYZ
48 melanotic neurilemmoma 10.2 CD68 LYZ
49 adult xanthogranuloma 10.2 CD68 LYZ
50 perinephritis 10.2

Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to Xanthogranulomatous Pyelonephritis

Symptoms & Phenotypes for Xanthogranulomatous Pyelonephritis

MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.32 CCL2 CD68 CPN1 CRP EGF ITGAX

Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

Search Clinical Trials , NIH Clinical Center for Xanthogranulomatous Pyelonephritis

Cochrane evidence based reviews: pyelonephritis, xanthogranulomatous

Genetic Tests for Xanthogranulomatous Pyelonephritis

Anatomical Context for Xanthogranulomatous Pyelonephritis

MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

38
Kidney, Lung, Liver, Colon, Monocytes, Pancreas, Bone

Publications for Xanthogranulomatous Pyelonephritis

Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50) (show all 466)
# Title Authors Year
1
Xanthogranulomatous pyelonephritis presenting as a type IV renal cyst. ( 28522934 )
2017
2
Xanthogranulomatous Pyelonephritis with Incomplete Double Ureter. ( 29075296 )
2017
3
High-grade transitional cell carcinoma masquerading as a xanthogranulomatous pyelonephritis and perinephric abscess. ( 28491170 )
2017
4
Massive Renal Replacement Lipomatosis With Foci of Xanthogranulomatous Pyelonephritis in a Horseshoe Kidney. ( 28443241 )
2017
5
Acute leukemia masquerading as xanthogranulomatous pyelonephritis. ( 28479773 )
2017
6
Spontaneous Nephrocutaneous Fistula: Rare Complication of Xanthogranulomatous Pyelonephritis. ( 28138432 )
2017
7
Xanthogranulomatous Pyelonephritis Manifesting as a Nephrocutaneous Fistula in a 5-Year-Old Female. ( 28131924 )
2017
8
Early Progression of Xanthogranulomatous Pyelonephritis in Children Might Be Dependent on Vimentin Expression. ( 28978905 )
2017
9
Xanthogranulomatous pyelonephritis in a paediatric cohort (1963-2016): Outcomes from a large single-center series. ( 29233628 )
2017
10
Xanthogranulomatous pyelonephritis presenting as acute pleuritic chest pain: a case report. ( 28399929 )
2017
11
Xanthogranulomatous pyelonephritis: a case with rare adhesion to pancreas. ( 29177841 )
2017
12
A Case of Xanthogranulomatous Pyelonephritis Associated with Renoduodenal Fistula. ( 28424736 )
2017
13
Xanthogranulomatous Pyelonephritis. ( 27743436 )
2016
14
Xanthogranulomatous pyelonephritis and renal tubulopapillary adenomas: A rare coexistence. ( 27721288 )
2016
15
Septic lung metastasis in xanthogranulomatous pyelonephritis. ( 27578950 )
2016
16
Xanthogranulomatous pyelonephritis presenting as Proteus preperitoneal abscess. ( 27915241 )
2016
17
Renal Sarcoidosis Mimicking Xanthogranulomatous Pyelonephritis. ( 27590254 )
2016
18
Primary kidney parenchyma squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: A case report. ( 26998145 )
2016
19
An unusual presentation of xanthogranulomatous pyelonephritis: psoas abscess with reno-colic fistula. ( 27471599 )
2016
20
Combination of Surgical Drainage and Renal Artery Embolization: An Alternative Treatment for Xanthogranulomatous Pyelonephritis. ( 28028578 )
2016
21
Renal squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: Case report and review of literature. ( 27257454 )
2016
22
Xanthogranulomatous Pyelonephritis. ( 27556196 )
2016
23
Xanthogranulomatous pyelonephritis presenting as a pseudotumour. ( 26858786 )
2016
24
Xanthogranulomatous pyelonephritis. ( 27307431 )
2016
25
Co-existing malakoplakia and xanthogranulomatous pyelonephritis of kidney: Two different spectrum of same disease process. ( 27141206 )
2016
26
A 13-Month-Old With Xanthogranulomatous Pyelonephritis With Features of Renal Malakoplakia. ( 26894199 )
2016
27
Bear's Paw Sign: A Classic Presentation of Xanthogranulomatous Pyelonephritis. ( 26168999 )
2015
28
Xanthogranulomatous Pyelonephritis with Staghorn Calculus, Acute Gangrenous Appendicitis and Enterocolitis: A Multidisciplinary Challenge of Kidney-Preserving Conservative Therapy. ( 26889137 )
2015
29
Xanthogranulomatous pyelonephritis with colesional actinomycosis in a 63-year-old man. ( 25878419 )
2015
30
Xanthogranulomatous Pyelonephritis Associated with Hepatic Dysfunction in Pregnancy. ( 26078894 )
2015
31
Xanthogranulomatous Pyelonephritis of a Lower Pole Moiety in a Duplicated Collecting System Kidney. ( 26435873 )
2015
32
Endometriosis in a kidney with focal xanthogranulomatous pyelonephritis and a perinephric abscess. ( 26490542 )
2015
33
Bilateral xanthogranulomatous pyelonephritis: Morphologically rotund, functionally lame! ( 26199481 )
2015
34
Rare Co-existence of Squamous Cell Carcinoma with Infiltration of Renal Vein and Xanthogranulomatous Pyelonephritis. ( 26816904 )
2015
35
Nephrobronchial fistula and lung abscess secondary to Xanthogranulomatous pyelonephritis. ( 26180394 )
2015
36
A case of xanthogranulomatous pyelonephritis mimicking Wilms tumor. ( 27186708 )
2015
37
A case report of a xanthogranulomatous pyelonephritis case mimicking the recurrence of renal cell carcinoma after partial nephrectomy. ( 26692680 )
2015
38
Xanthogranulomatous pyelonephritis: the case of a perplexing kidney. ( 25240002 )
2014
39
Ureteral calculi combined with xanthogranulomatous pyelonephritis mimicking renal tuberculosis in a male child. ( 25458052 )
2014
40
Xanthogranulomatous pyelonephritis mimicking a renal cell carcinoma: a unique and challenging case. ( 24778797 )
2014
41
Xanthogranulomatous pyelonephritis: critical analysis of 18 cases from a rural tertiary care centre of India. ( 25935947 )
2014
42
Xanthogranulomatous pyelonephritis presenting as palmoplantar keratoderma. ( 25519870 )
2014
43
Primary renal aspergillosis and xanthogranulomatous pyelonephritis in an immuno-competent toddler. ( 24906255 )
2014
44
Analysis of 35 cases of Xanthogranulomatous pyelonephritis. ( 24661744 )
2014
45
Xanthogranulomatous pyelonephritis masquerading as a tumor in an infant. ( 25097328 )
2014
46
Laparascopic-assisted nephroureterectomy for shaped urolithiasis and xanthogranulomatous pyelonephritis: case report and review of literature. ( 24192478 )
2013
47
Adolescent xanthogranulomatous pyelonephritis mimicking renal cell carcinoma on urine cytology: an atypical presentation. ( 23394878 )
2013
48
Xanthogranulomatous pyelonephritis presenting with a left flank mass. ( 24367381 )
2013
49
The role of laparoscopic nephrectomy in pediatric xanthogranulomatous pyelonephritis: a case report. ( 23533930 )
2013
50
Xanthogranulomatous pyelonephritis: clinical experience with 21 cases. ( 23708781 )
2013

Variations for Xanthogranulomatous Pyelonephritis

Expression for Xanthogranulomatous Pyelonephritis

Search GEO for disease gene expression data for Xanthogranulomatous Pyelonephritis.

Pathways for Xanthogranulomatous Pyelonephritis

Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.23 CCL2 SERPINA3
2 9.83 CCL2 CD68

GO Terms for Xanthogranulomatous Pyelonephritis

Biological processes related to Xanthogranulomatous Pyelonephritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.26 CCL2 CRP LYZ SERPINA3
2 animal organ morphogenesis GO:0009887 8.8 CCL2 HCCS ITGAX

Sources for Xanthogranulomatous Pyelonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
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29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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35 IUPHAR
36 KEGG
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39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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