MCID: XNT001
MIFTS: 41

Xanthogranulomatous Pyelonephritis malady

Nephrological diseases category
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Summaries for Xanthogranulomatous Pyelonephritis

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MalaCards based summary: Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to pneumonia and pyelonephritis. An important gene associated with Xanthogranulomatous Pyelonephritis is MUC1 (mucin 1, cell surface associated), and among its related pathways are EGFR Signaling Pathway and Development EGFR signaling pathway. The compounds trastuzumab and progestin have been mentioned in the context of this disorder. Affiliated tissues include kidney, colon and liver, and related mouse phenotypes are normal and liver/biliary system.

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

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Xanthogranulomatous Pyelonephritis, Aliases & Descriptions:

Name: Xanthogranulomatous Pyelonephritis 8 10
 
Pyelonephritis, Xanthogranulomatous 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


External Ids:

Disease Ontology8 DOID:11401
SNOMED-CT57 38898003, 197777006
MeSH34 D011705

Related Diseases for Xanthogranulomatous Pyelonephritis

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Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to xanthogranulomatous pyelonephritis

Symptoms for Xanthogranulomatous Pyelonephritis

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Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

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Drug clinical trials:

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Search NIH Clinical Center for Xanthogranulomatous Pyelonephritis

Genetic Tests for Xanthogranulomatous Pyelonephritis

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Anatomical Context for Xanthogranulomatous Pyelonephritis

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MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

32
Kidney, Colon, Liver, Bone, Spinal cord, Lung, Monocytes

Animal Models for Xanthogranulomatous Pyelonephritis or affiliated genes

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MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.6EGF, CCL2, MUC1
2MP:00053708.4MUC1, CCL2, ERCC5
3MP:00053918.3EGF, CCL2, MUC1
4MP:00053818.1EGF, ERCC5, CCL2, MUC1
5MP:00107718.0EGF, ERCC5, CCL2, MUC1

Publications for Xanthogranulomatous Pyelonephritis

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Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50)    (show all 422)
idTitleAuthorsYear
1
Xanthogranulomatous pyelonephritis: the case of a perplexing kidney. (25240002)
2014
2
Analysis of 35 cases of Xanthogranulomatous pyelonephritis. (24661744)
2014
3
Xanthogranulomatous pyelonephritis masquerading as a tumor in an infant. (25097328)
2014
4
Nephrobronchial fistula complicating neglected nephrolithiasis and xanthogranulomatous pyelonephritis. (21566318)
2011
5
Xanthogranulomatous pyelonephritis in a horse-shoe kidney. (20427880)
2010
6
Puzzles in practice. Xanthogranulomatous pyelonephritis (XGP). (21084798)
2010
7
Xanthogranulomatous pyelonephritis in an adolescent. (20579704)
2010
8
Xanthogranulomatous pyelonephritis infiltrating the liver. (18926204)
2008
9
Renal parenchymal malacoplakia: a different stage of xanthogranulomatous pyelonephritis? (17618870)
2007
10
Images in emergency medicine. Xanthogranulomatous pyelonephritis. (17709049)
2007
11
Xanthogranulomatous pyelonephritis is associated with higher tissue expression of monocyte chemotactic protein-1. (17968796)
2007
12
Xanthogranulomatous pyelonephritis. (16481231)
2006
13
Hand-assisted laparoscopic nephrectomy for xanthogranulomatous pyelonephritis with nephrocutaneous fistula after failed flank exploration. (16921310)
2006
14
Co-existent massive renal replacement lipomatosis and xanthogranulomatous pyelonephritis--a case report. (15025379)
2003
15
Xanthogranulomatous pyelonephritis in a dysplastic kidney with reflux associated with posterior urethral valves. (11832763)
2002
16
Intra-abdominal actinomycosis with hepatic pseudotumor and xanthogranulomatous pyelonephritis in a 6-y-old boy. (11515770)
2001
17
Xanthogranulomatous pyelonephritis: urinary and fine needle aspiration cytology. (9684612)
1998
18
Focal xanthogranulomatous pyelonephritis in a teenager. (9717648)
1998
19
Xanthogranulomatous pyelonephritis presenting as a psoas abscess in a child. (8800918)
1996
20
Xanthogranulomatous pyelonephritis associated with transitional cell carcinoma of the renal pelvis. (8961496)
1996
21
Xanthogranulomatous pyelonephritis in pediatric patients. (7752369)
1995
22
Focal xanthogranulomatous pyelonephritis in a young child. (7936803)
1994
23
Image interpretation session. Focal xanthogranulomatous pyelonephritis. (1734468)
1992
24
Xanthogranulomatous pyelonephritis with nephrocutaneous fistula at the knee. (2070215)
1991
25
Xanthogranulomatous pyelonephritis. A report of two cases. (2152092)
1990
26
Xanthogranulomatous pyelonephritis in children and adults--an 8 year study. (2091999)
1990
27
Xanthogranulomatous pyelonephritis--(a clinicopathological study of 15 cases) (2490367)
1989
28
Xanthogranulomatous pyelonephritis. A reappraisal and immunohistochemical study. (3345125)
1988
29
Ultrasonography and needle aspiration in diagnosis of xanthogranulomatous pyelonephritis. (3544457)
1987
30
Xanthogranulomatous pyelonephritis with reno-colonic and cutaneous fistulae. (3676680)
1987
31
Serendipitous diagnosis of childhood xanthogranulomatous pyelonephritis in a child with osteomyelitis. (3550670)
1987
32
Generalized amyloidosis secondary to xanthogranulomatous pyelonephritis. (3816863)
1986
33
Xanthogranulomatous pyelonephritis in children. (3968740)
1985
34
Computed tomography of xanthogranulomatous pyelonephritis presenting as a flank mass. (4053662)
1985
35
Xanthogranulomatous pyelonephritis with bilharzial ureteric obstruction. (6653472)
1983
36
Biliary obstruction due to xanthogranulomatous pyelonephritis. (7120490)
1982
37
Diffuse xanthogranulomatous pyelonephritis: analysis by computed tomography and sonography. (7101607)
1982
38
Xanthogranulomatous pyelonephritis associated with renal carcinoma. (7411698)
1980
39
The underestimated hazards of xanthogranulomatous pyelonephritis. (534821)
1979
40
Xanthogranulomatous pyelonephritis (XGP): a local disease with systemic manifestations. Report of 23 patients and review of the literature. (431402)
1979
41
Bilateral diffuse xanthogranulomatous pyelonephritis. (465976)
1979
42
Xanthogranulomatous pyelonephritis in children. (320349)
1977
43
Xanthogranulomatous pyelonephritis. Angiographic evaluation. (4591220)
1974
44
Peripartum hepatic dysfunction and xanthogranulomatous pyelonephritis. (4576472)
1973
45
Xanthogranulomatous pyelonephritis: a comprehensive review with report of 4 additional cases. (5100861)
1971
46
Xanthogranulomatous pyelonephritis. (5804197)
1969
47
Xanthogranulomatous pyelonephritis. A case report with angiographic findings. (5931830)
1966
48
Xanthogranulomatous pyelonephritis. (5905474)
1966
49
XANTHOGRANULOMATOUS PYELONEPHRITIS: CONFUSION WITH RENAL CARCINOMA. (14217946)
1964
50
XANTHOGRANULOMATOUS PYELONEPHRITIS. (14134284)
1963

Variations for Xanthogranulomatous Pyelonephritis

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Expression for genes affiliated with Xanthogranulomatous Pyelonephritis

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Expression patterns in normal tissues for genes affiliated with Xanthogranulomatous Pyelonephritis

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Pathways for genes affiliated with Xanthogranulomatous Pyelonephritis

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Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4EGF, MUC1
2
Show member pathways
Development ERBB family signaling60
Development GDNF family signaling60
9.4EGF, MUC1
3
Show member pathways
8.6EGF, CCL2, MUC1

Compounds for genes affiliated with Xanthogranulomatous Pyelonephritis

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Compounds related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

(show all 37)
idCompoundScoreTop Affiliating Genes
1trastuzumab44 50 1111.8MUC1, EGF
2progestin449.8EGF, MUC1
3gemcitabine44 50 1111.8MUC1, EGF
4hydrocortisone44 2 61 1112.8EGF, MUC1
5dihydrotestosterone44 28 24 1112.7EGF, MUC1
6matrigel449.7EGF, MUC1
712-o-tetradecanoylphorbol 13-acetate449.6MUC1, EGF
8butyrate449.5EGF, MUC1
9shikonin449.5EGF, CCL2
10hcec449.5EGF, CCL2
11ro 31 8220449.5EGF, CCL2
12go 697644 6110.5EGF, CCL2
13ang ii449.5CCL2, EGF
14pertussis449.5CCL2, EGF
15tamoxifen44 50 28 1112.5MUC1, EGF
16cytochalasin d44 6110.5EGF, CCL2
17egcg449.5CCL2, EGF
18mg 13244 6110.4EGF, CCL2
19tgf beta1449.4CCL2, EGF
20herbimycin a44 6110.4EGF, CCL2
21formaldehyde44 2410.4CCL2, MUC1
22gnrh449.4CCL2, EGF
23ribonucleic acid449.4MUC1, CCL2
24sb 20358044 6110.3EGF, CCL2
25polysaccharide449.1CCL2, MUC1
26wortmannin449.1EGF, CCL2
27pd 98,059449.0EGF, CCL2
28mifepristone44 28 61 1112.0MUC1, CCL2, EGF
295fluorouracil449.0EGF, CCL2, MUC1
30agar449.0MUC1, CCL2, EGF
31actinomycin d449.0MUC1, CCL2, EGF
32testosterone44 61 24 1112.0EGF, CCL2, MUC1
33dexamethasone44 50 28 1112.0EGF, CCL2, MUC1
34vegf449.0MUC1, CCL2, EGF
35ly294002448.8EGF, CCL2
36serine448.8EGF, CCL2, MUC1
37cisplatin44 50 61 1111.4EGF, ERCC5, CCL2, MUC1

GO Terms for genes affiliated with Xanthogranulomatous Pyelonephritis

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Biological processes related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1angiogenesisGO:0015259.1EGF, CCL2

Products for genes affiliated with Xanthogranulomatous Pyelonephritis

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Sources for Xanthogranulomatous Pyelonephritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet