MCID: XNT001
MIFTS: 37

Xanthogranulomatous Pyelonephritis malady

Summaries for Xanthogranulomatous Pyelonephritis

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33MalaCards
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MalaCards: Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to adenocarcinoma and adenoma. An important gene associated with Xanthogranulomatous Pyelonephritis is ERCC5 (excision repair cross-complementing rodent repair deficiency, complementation group 5), and among its related pathways is EGFR Signaling Pathway. The compounds shikonin and ro 31 8220 have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, colon and kidney, and related mouse phenotypes are digestive/alimentary and liver/biliary system.

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 35MeSH
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Aliases & Descriptions:

xanthogranulomatous pyelonephritis 8 10
pyelonephritis, xanthogranulomatous 61


External Ids:

Disease Ontology8 DOID:11401
SNOMED-CT57 197777006, 38898003
MeSH35 D011705

Related Diseases for Xanthogranulomatous Pyelonephritis

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17GeneCards, 18GeneDecks
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Diseases related to Xanthogranulomatous Pyelonephritis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 66)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma30.5MUC1, EGF, SCG5
2adenoma30.2MUC1, SCG5
3amyloidosis10.6
4malakoplakia10.5
5adult xanthogranuloma10.5
6amyloidosis, secondary10.5
7acute pyelonephritis10.4
8renal tuberculosis10.4
9tuberculosis10.4
10nephrolithiasis10.3
11n syndrome10.3
12transitional cell carcinoma10.3
13horseshoe kidney10.3
14megalocytic interstitial nephritis10.3
15amyloidosis, renal10.3
16nephritis10.3
17hepatic tuberculosis10.2
18hepatitis c10.2
19papillary carcinoma10.2
20chronic granulomatous disease10.2
21papillary renal cell carcinoma10.2
22yellow nail syndrome10.2
23systemic lupus erythematosus10.2
24small cell carcinoma10.2
25keratinizing squamous cell carcinoma10.2
26bronchiectasis10.2
27cystinuria10.2
28actinomycosis10.2
29polycystic kidney disease10.2
30mucinous adenocarcinoma10.2
31renal pelvis adenocarcinoma10.2
32kidney lipoma10.2
33papillary adenoma10.2
34acute kidney failure10.2
35autosomal dominant disease10.2
36squamous cell carcinoma10.2
37thrombocytopenia10.2
38polycystic kidney disease, autosomal dominant10.2
39wilms tumor10.2
40fibrosing mediastinitis10.2
41klebsiella10.2
42posterior urethral valves10.2
43posterior valve urethra10.2
44superior vena cava syndrome10.2
45papillary renal carcinoma10.2
46spinal cord injury10.2
47sepsis10.2
48posterior urethral valve10.2
49metanephric adenoma10.0SRMS
50ependymoma10.0MUC1

Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to xanthogranulomatous pyelonephritis

Clinical Features for Xanthogranulomatous Pyelonephritis

Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Xanthogranulomatous Pyelonephritis

Drug clinical trials:

Search ClinicalTrials for Xanthogranulomatous Pyelonephritis

Search NIH Clinical Center for Xanthogranulomatous Pyelonephritis

Search CenterWatch for Xanthogranulomatous Pyelonephritis

Genetic Tests for Xanthogranulomatous Pyelonephritis

Anatomical Context for Xanthogranulomatous Pyelonephritis

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33MalaCards
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MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

33
Spinal cord, Colon, Kidney, Liver, Lung, Monocytes

Animal Models for Xanthogranulomatous Pyelonephritis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.7ERCC5, MUC1, EGF, CCL2
2MP:00053708.1CCL2, SCG5, MUC1, ERCC5
3MP:00107717.8ERCC5, MUC1, EGF, SCG5, CCL2

Publications for Xanthogranulomatous Pyelonephritis

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51PubMed
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Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50)    (show all 421)
idTitleAuthorsYear
1
Xanthogranulomatous pyelonephritis presenting with thrombocytopenia and renal mass. (22346104)
2012
2
Xanthogranulomatous pyelonephritis in Korean children. (23074117)
2012
3
Xanthogranulomatous pyelonephritis with unconnected liver lesion. (21094988)
2011
4
Xanthogranulomatous pyelonephritis presentation in the ED: a case report. (19931791)
2009
5
Laparoscopic heminephrectomy in a horseshoe kidney affected by xanthogranulomatous pyelonephritis. (19793497)
2009
6
Bilateral xanthogranulomatous pyelonephritis. (18567562)
2008
7
Rare coexistence of keratinizing squamous metaplasia with xanthogranulomatous pyelonephritis. Report of a case with the role of immunocytochemistry in the differential diagnosis. (17328505)
2007
8
Xanthogranulomatous pyelonephritis: our experience with review of published reports. (17054551)
2006
9
Aspiration cytology of focal xanthogranulomatous pyelonephritis: a diagnostic challenge. (14755763)
2004
10
Ultrasonographic features of focal xanthogranulomatous pyelonephritis. (15055789)
2004
11
Intra-abdominal actinomycosis with hepatic pseudotumor and xanthogranulomatous pyelonephritis in a 6-y-old boy. (11515770)
2001
12
Xanthogranulomatous pyelonephritis associated with a congenital caliceal diverticulum. (11164173)
2001
13
Chronic nephrotic syndrome and chronic renal failure by amyloidosis secondary to xanthogranulomatous pyelonephritis. (9491290)
1998
14
Diffuse xanthogranulomatous pyelonephritis in childhood. (9142621)
1997
15
Xanthogranulomatous pyelonephritis--an unusual renal disease in childhood. (8640064)
1996
16
Focal xanthogranulomatous pyelonephritis presenting as renal tumour in children. Case report with a review of the literature. (8837258)
1996
17
Xanthogranulomatous pyelonephritis in pediatric patients. (7752369)
1995
18
Xanthogranulomatous pyelonephritis: clinical findings and surgical considerations. (8134982)
1994
19
Xanthogranulomatous pyelonephritis in renal allografts: report of 2 cases. (8254789)
1994
20
Xanthogranulomatous pyelonephritis and Wilms' tumour. (8149158)
1993
21
Xanthogranulomatous pyelonephritis: experience in 36 cases. (1732587)
1992
22
Xanthogranulomatous pyelonephritis and systemic amyloidosis: report of 2 new cases and the natural history of this association. (1942352)
1991
23
Renal parenchymal malakoplakia. Histologic spectrum and its relationship to megalocytic interstitial nephritis and xanthogranulomatous pyelonephritis. (2919720)
1989
24
Evolving concepts in the diagnosis of xanthogranulomatous pyelonephritis. (2660387)
1989
25
Xanthogranulomatous pyelonephritis. A reappraisal and immunohistochemical study. (3345125)
1988
26
Development of fatal bilateral xanthogranulomatous pyelonephritis in a paraplegic patient: case report. (3281100)
1988
27
Serendipitous diagnosis of childhood xanthogranulomatous pyelonephritis in a child with osteomyelitis. (3550670)
1987
28
Xanthogranulomatous pyelonephritis in the spinal cord injury patient: a complication of urolithiasis. (3450777)
1987
29
Xanthogranulomatous pyelonephritis in children. (3672681)
1987
30
Generalized amyloidosis secondary to xanthogranulomatous pyelonephritis. (3816863)
1986
31
Xanthogranulomatous pyelonephritis in children. Report of 7 cases and one associated with nephroblastoma. (3017018)
1986
32
Xanthogranulomatous pyelonephritis associated with pyeloduodenal fistula. (4041744)
1985
33
Xanthogranulomatous pyelonephritis. (2863638)
1985
34
Xanthogranulomatous pyelonephritis (report of 2 cases). (6716307)
1984
35
Computerized tomography in xanthogranulomatous pyelonephritis. (6876281)
1983
36
Chronic granulomatous disease presenting as xanthogranulomatous pyelonephritis in late childhood. (6799633)
1982
37
CAT scan of the month: xanthogranulomatous pyelonephritis. (7311522)
1981
38
Xanthogranulomatous pyelonephritis: a report of 40 cases. (7228606)
1980
39
Renojejunal fistula caused by xanthogranulomatous pyelonephritis. (7426957)
1980
40
Xanthogranulomatous pyelonephritis in childhood. (7441466)
1980
41
Xanthogranulomatous pyelonephritis in a child. A case report. (7216327)
1980
42
Xanthogranulomatous pyelonephritis presenting with unilateral renal vein thrombosis. (7433333)
1980
43
Xanthogranulomatous pyelonephritis. (4686855)
1973
44
Xanthogranulomatous pyelonephritis in a three-year-old male. (4329773)
1971
45
Xanthogranulomatous pyelonephritis and perirenal xanthogranuloma. (5683568)
1968
46
XANTHOGRANULOMATOUS PYELONEPHRITIS. (14346447)
1965
47
XANTHOGRANULOMATOUS PYELONEPHRITIS: CONFUSION WITH RENAL CARCINOMA. (14217946)
1964
48
XANTHOGRANULOMATOUS PYELONEPHRITIS. (14241184)
1964
49
Xanthogranulomatous pyelonephritis. (14018147)
1963
50
Tumefactive xanthogranulomatous pyelonephritis. (13965673)
1963

Genetic Variations for Xanthogranulomatous Pyelonephritis

Expression for genes affiliated with Xanthogranulomatous Pyelonephritis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Xanthogranulomatous Pyelonephritis

Search GEO for disease gene expression data for Xanthogranulomatous Pyelonephritis.

Pathways for genes affiliated with Xanthogranulomatous Pyelonephritis

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56SinoBiological
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Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5MUC1, EGF

Compounds for genes affiliated with Xanthogranulomatous Pyelonephritis

Sources:
45Novoseek, 60Tocris Bioscience, 29IUPHAR, 11DrugBank, 50PharmGKB, 24HMDB
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Compounds related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

(show all 20)
idCompoundScoreTop Affiliating Genes
1shikonin459.8EGF, CCL2
2ro 31 8220459.8CCL2, EGF
3hcec459.8CCL2, EGF
4go 697645 6010.7EGF, CCL2
5pertussis459.6CCL2, EGF
6ang ii459.6CCL2, EGF
7mifepristone45 60 29 1112.4MUC1, EGF, CCL2
8hirudin459.4CCL2, SCG5
95fluorouracil459.4CCL2, EGF, MUC1
10agar459.3MUC1, EGF, CCL2
11trastuzumab45 50 1111.2MUC1, EGF
12actinomycin d459.2MUC1, EGF, CCL2
13cisplatin45 50 60 1112.0ERCC5, MUC1, EGF, CCL2
14polysaccharide459.0MUC1, SCG5, CCL2
15butyrate459.0SCG5, EGF, MUC1
16paraffin458.8MUC1, SCG5, CCL2
17thymidine45 249.7MUC1, EGF, SCG5
18testosterone45 60 11 2411.6CCL2, SCG5, EGF, MUC1
19glutamine458.6CCL2, SCG5, EGF
20dexamethasone45 50 29 1111.5MUC1, EGF, SCG5, CCL2

GO Terms for genes affiliated with Xanthogranulomatous Pyelonephritis

Products for genes affiliated with Xanthogranulomatous Pyelonephritis

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Sources for Xanthogranulomatous Pyelonephritis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet