MCID: XNT001
MIFTS: 41

Xanthogranulomatous Pyelonephritis malady

Nephrological diseases category

Summaries for Xanthogranulomatous Pyelonephritis

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34MalaCards
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MalaCards: Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to pneumonia and pyelonephritis. An important gene associated with Xanthogranulomatous Pyelonephritis is MUC1 (mucin 1, cell surface associated), and among its related pathways are EGFR Signaling Pathway and Development EGFR signaling pathway. The compounds trastuzumab and progestin have been mentioned in the context of this disorder. Affiliated tissues include kidney, colon and liver, and related mouse phenotypes are normal and liver/biliary system.

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

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9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


Aliases & Descriptions:

xanthogranulomatous pyelonephritis 9 11
pyelonephritis, xanthogranulomatous 63


External Ids:

Disease Ontology9 DOID:11401
SNOMED-CT59 38898003, 197777006
MeSH36 D011705

Related Diseases for Xanthogranulomatous Pyelonephritis

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to xanthogranulomatous pyelonephritis

Symptoms for Xanthogranulomatous Pyelonephritis

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Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Xanthogranulomatous Pyelonephritis

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Anatomical Context for Xanthogranulomatous Pyelonephritis

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34MalaCards
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MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

34
Kidney, Colon, Liver, Bone, Spinal cord, Lung, Monocytes

Animal Models for Xanthogranulomatous Pyelonephritis or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.6EGF, CCL2, MUC1
2MP:00053708.4MUC1, CCL2, ERCC5
3MP:00053918.3EGF, CCL2, MUC1
4MP:00053818.1EGF, ERCC5, CCL2, MUC1
5MP:00107718.0EGF, ERCC5, CCL2, MUC1

Publications for Xanthogranulomatous Pyelonephritis

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53PubMed
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Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50)    (show all 417)
idTitleAuthorsYear
1
Renal replacement lipomatosis with coexistent papillary renal cell carcinoma, renal tubulopapillary adenomatosis, and xanthogranulomatous pyelonephritis: an extremely rare association and possible pathogenetic correlation. (23801477)
2013
2
Nephrobronchial fistula complicating neglected nephrolithiasis and xanthogranulomatous pyelonephritis. (21566318)
2011
3
Xanthogranulomatous pyelonephritis in a horse-shoe kidney. (20427880)
2010
4
Puzzles in practice. Xanthogranulomatous pyelonephritis (XGP). (21084798)
2010
5
Xanthogranulomatous pyelonephritis in an adolescent. (20579704)
2010
6
Xanthogranulomatous pyelonephritis infiltrating the liver. (18926204)
2008
7
Renal parenchymal malacoplakia: a different stage of xanthogranulomatous pyelonephritis? (17618870)
2007
8
Images in emergency medicine. Xanthogranulomatous pyelonephritis. (17709049)
2007
9
Xanthogranulomatous pyelonephritis is associated with higher tissue expression of monocyte chemotactic protein-1. (17968796)
2007
10
Xanthogranulomatous pyelonephritis. (16481231)
2006
11
Hand-assisted laparoscopic nephrectomy for xanthogranulomatous pyelonephritis with nephrocutaneous fistula after failed flank exploration. (16921310)
2006
12
Co-existent massive renal replacement lipomatosis and xanthogranulomatous pyelonephritis--a case report. (15025379)
2003
13
Xanthogranulomatous pyelonephritis in a dysplastic kidney with reflux associated with posterior urethral valves. (11832763)
2002
14
Intra-abdominal actinomycosis with hepatic pseudotumor and xanthogranulomatous pyelonephritis in a 6-y-old boy. (11515770)
2001
15
Xanthogranulomatous pyelonephritis: urinary and fine needle aspiration cytology. (9684612)
1998
16
Focal xanthogranulomatous pyelonephritis in a teenager. (9717648)
1998
17
Xanthogranulomatous pyelonephritis presenting as a psoas abscess in a child. (8800918)
1996
18
Xanthogranulomatous pyelonephritis associated with transitional cell carcinoma of the renal pelvis. (8961496)
1996
19
Xanthogranulomatous pyelonephritis in pediatric patients. (7752369)
1995
20
Focal xanthogranulomatous pyelonephritis in a young child. (7936803)
1994
21
Image interpretation session. Focal xanthogranulomatous pyelonephritis. (1734468)
1992
22
Xanthogranulomatous pyelonephritis with nephrocutaneous fistula at the knee. (2070215)
1991
23
Xanthogranulomatous pyelonephritis. A report of two cases. (2152092)
1990
24
Xanthogranulomatous pyelonephritis in children and adults--an 8 year study. (2091999)
1990
25
Xanthogranulomatous pyelonephritis--(a clinicopathological study of 15 cases) (2490367)
1989
26
Xanthogranulomatous pyelonephritis. A reappraisal and immunohistochemical study. (3345125)
1988
27
Ultrasonography and needle aspiration in diagnosis of xanthogranulomatous pyelonephritis. (3544457)
1987
28
Xanthogranulomatous pyelonephritis with reno-colonic and cutaneous fistulae. (3676680)
1987
29
Serendipitous diagnosis of childhood xanthogranulomatous pyelonephritis in a child with osteomyelitis. (3550670)
1987
30
Generalized amyloidosis secondary to xanthogranulomatous pyelonephritis. (3816863)
1986
31
Xanthogranulomatous pyelonephritis in children. (3968740)
1985
32
Computed tomography of xanthogranulomatous pyelonephritis presenting as a flank mass. (4053662)
1985
33
Xanthogranulomatous pyelonephritis with bilharzial ureteric obstruction. (6653472)
1983
34
Biliary obstruction due to xanthogranulomatous pyelonephritis. (7120490)
1982
35
Diffuse xanthogranulomatous pyelonephritis: analysis by computed tomography and sonography. (7101607)
1982
36
Xanthogranulomatous pyelonephritis associated with renal carcinoma. (7411698)
1980
37
Xanthogranulomatous pyelonephritis: a report of 40 cases. (7228606)
1980
38
The underestimated hazards of xanthogranulomatous pyelonephritis. (534821)
1979
39
Xanthogranulomatous pyelonephritis (XGP): a local disease with systemic manifestations. Report of 23 patients and review of the literature. (431402)
1979
40
Bilateral diffuse xanthogranulomatous pyelonephritis. (465976)
1979
41
Xanthogranulomatous pyelonephritis in children. (320349)
1977
42
Xanthogranulomatous pyelonephritis. (562462)
1977
43
Xanthogranulomatous pyelonephritis. Angiographic evaluation. (4591220)
1974
44
Peripartum hepatic dysfunction and xanthogranulomatous pyelonephritis. (4576472)
1973
45
Xanthogranulomatous pyelonephritis: a comprehensive review with report of 4 additional cases. (5100861)
1971
46
Xanthogranulomatous pyelonephritis. (5804197)
1969
47
Xanthogranulomatous pyelonephritis. A case report with angiographic findings. (5931830)
1966
48
Xanthogranulomatous pyelonephritis. (5905474)
1966
49
XANTHOGRANULOMATOUS PYELONEPHRITIS: CONFUSION WITH RENAL CARCINOMA. (14217946)
1964
50
XANTHOGRANULOMATOUS PYELONEPHRITIS. (14134284)
1963

Variations for Xanthogranulomatous Pyelonephritis

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Expression for genes affiliated with Xanthogranulomatous Pyelonephritis

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Xanthogranulomatous Pyelonephritis

Search GEO for disease gene expression data for Xanthogranulomatous Pyelonephritis.

Pathways for genes affiliated with Xanthogranulomatous Pyelonephritis

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51PathCards, 58SinoBiological, 61Thomson Reuters, 54QIAGEN, 56Reactome
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Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4EGF, MUC1
2
Show member pathways
Development ERBB family signaling61
Development GDNF family signaling61
9.4EGF, MUC1
3
Show member pathways
8.6EGF, CCL2, MUC1

Compounds for genes affiliated with Xanthogranulomatous Pyelonephritis

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46Novoseek, 52PharmGKB, 12DrugBank, 3BitterDB, 62Tocris Bioscience, 30IUPHAR, 25HMDB
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Compounds related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

(show all 37)
idCompoundScoreTop Affiliating Genes
1trastuzumab46 52 1211.8MUC1, EGF
2progestin469.8EGF, MUC1
3gemcitabine46 52 1211.8MUC1, EGF
4hydrocortisone46 3 62 1212.8EGF, MUC1
5dihydrotestosterone46 30 25 1212.7EGF, MUC1
6matrigel469.7EGF, MUC1
712-o-tetradecanoylphorbol 13-acetate469.6MUC1, EGF
8butyrate469.5EGF, MUC1
9shikonin469.5EGF, CCL2
10hcec469.5EGF, CCL2
11ro 31 8220469.5EGF, CCL2
12go 697646 6210.5EGF, CCL2
13ang ii469.5CCL2, EGF
14pertussis469.5CCL2, EGF
15tamoxifen46 52 30 1212.5MUC1, EGF
16cytochalasin d46 6210.5EGF, CCL2
17egcg469.5CCL2, EGF
18mg 13246 6210.4EGF, CCL2
19tgf beta1469.4CCL2, EGF
20herbimycin a46 6210.4EGF, CCL2
21formaldehyde46 2510.4CCL2, MUC1
22gnrh469.4CCL2, EGF
23ribonucleic acid469.4MUC1, CCL2
24sb 20358046 6210.3EGF, CCL2
25polysaccharide469.1CCL2, MUC1
26wortmannin469.1EGF, CCL2
27pd 98,059469.0EGF, CCL2
28mifepristone46 30 62 1212.0MUC1, CCL2, EGF
295fluorouracil469.0EGF, CCL2, MUC1
30agar469.0MUC1, CCL2, EGF
31actinomycin d469.0MUC1, CCL2, EGF
32testosterone46 62 25 1212.0EGF, CCL2, MUC1
33dexamethasone46 52 30 1212.0EGF, CCL2, MUC1
34vegf469.0MUC1, CCL2, EGF
35ly294002468.8EGF, CCL2
36serine468.8EGF, CCL2, MUC1
37cisplatin46 52 62 1211.4EGF, ERCC5, CCL2, MUC1

GO Terms for genes affiliated with Xanthogranulomatous Pyelonephritis

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17Gene Ontology
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Biological processes related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1angiogenesisGO:0015259.1EGF, CCL2

Products for genes affiliated with Xanthogranulomatous Pyelonephritis

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Sources for Xanthogranulomatous Pyelonephritis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet