MCID: XNT001
MIFTS: 38

Xanthogranulomatous Pyelonephritis malady

Summaries for Xanthogranulomatous Pyelonephritis

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32MalaCards
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MalaCards: Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to adenocarcinoma and pyelonephritis. An important gene associated with Xanthogranulomatous Pyelonephritis is ERCC5 (excision repair cross-complementing rodent repair deficiency, complementation group 5), and among its related pathways is EGFR Signaling Pathway. The compounds shikonin and ro 31 8220 have been mentioned in the context of this disorder. Affiliated tissues include kidney, colon and liver, and related mouse phenotypes are digestive/alimentary and liver/biliary system.

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

xanthogranulomatous pyelonephritis 8 10
pyelonephritis, xanthogranulomatous 60


External Ids:

Disease Ontology8 DOID:11401
SNOMED-CT56 197777006, 38898003
MeSH34 D011705

Related Diseases for Xanthogranulomatous Pyelonephritis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to xanthogranulomatous pyelonephritis

Clinical Features for Xanthogranulomatous Pyelonephritis

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Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Xanthogranulomatous Pyelonephritis

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Anatomical Context for Xanthogranulomatous Pyelonephritis

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32MalaCards
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MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

32
Kidney, Colon, Liver, Bone, Spinal cord, Lung, Monocytes

Animal Models for Xanthogranulomatous Pyelonephritis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.7ERCC5, MUC1, EGF, CCL2
2MP:00053708.1CCL2, SCG5, MUC1, ERCC5
3MP:00107717.8ERCC5, MUC1, EGF, SCG5, CCL2

Publications for Xanthogranulomatous Pyelonephritis

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50PubMed
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Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50)    (show all 421)
idTitleAuthorsYear
1
Xanthogranulomatous pyelonephritis presenting with a left flank mass. (24367381)
2013
2
Xanthogranulomatous pyelonephritis in a male child--a case report with a brief review of literature. (23738410)
2012
3
Nephrobronchial fistula complicating neglected nephrolithiasis and xanthogranulomatous pyelonephritis. (21566318)
2011
4
Xanthogranulomatous pyelonephritis: A rare entity. (22558604)
2011
5
Laparoscopic versus open nephrectomy for xanthogranulomatous pyelonephritis: An outcome analysis. (22279311)
2011
6
Medical image. Xanthogranulomatous pyelonephritis. (22072173)
2011
7
Xanthogranulomatous pyelonephritis: an uncommon pediatric renal mass. (20151117)
2010
8
Amyloidosis secondary to xanthogranulomatous pyelonephritis: a rare association. (20587879)
2010
9
Xanthogranulomatous pyelonephritis in childhood: diagnosis difficulties and success of conservative treatment. (20517855)
2010
10
Successfully treated bilateral xanthogranulomatous pyelonephritis in a child. (18446378)
2008
11
Acute retroperitoneal hemorrhage complicating a xanthogranulomatous pyelonephritis. (16855836)
2007
12
Xanthogranulomatous pyelonephritis. (16481231)
2006
13
Hand-assisted laparoscopic nephrectomy for xanthogranulomatous pyelonephritis with nephrocutaneous fistula after failed flank exploration. (16921310)
2006
14
Diffuse xanthogranulomatous pyelonephritis in a child with severe complications. (15378422)
2004
15
Coexistence of renal replacement lipomatosis with xanthogranulomatous pyelonephritis. (14678184)
2004
16
Quiz page. Xanthogranulomatous pyelonephritis. (12955712)
2003
17
Xanthogranulomatous pyelonephritis: a retrospective study of 10 cases and review of the literature. (18209396)
2001
18
Xanthogranulomatous pyelonephritis in childhood. (11283885)
2001
19
Xanthogranulomatous pyelonephritis and renal malignancy: unusual fellows in the renal bed. (10971292)
2000
20
Xanthogranulomatous pyelonephritis. (10472491)
1999
21
Xanthogranulomatous pyelonephritis presenting as emphysematous pyelonephritis: a rare association. (10734353)
1999
22
Xanthogranulomatous pyelonephritis in a child with cystinuria. (9730722)
1998
23
Focal xanthogranulomatous pyelonephritis mimicking a renal tumor: CT- and MR-findings and evolution under therapy. (9175063)
1997
24
Focal xanthogranulomatous pyelonephritis in a teenager: MR and CT findings. (9056155)
1997
25
Focal xanthogranulomatous pyelonephritis: partial nephrectomy as definitive treatment. (9358230)
1997
26
Pseudoneoplastic xanthogranulomatous pyelonephritis. A typical clinical presentation but unusual diagnosis and treatment. (7744162)
1995
27
Intrapelvic Wilms' tumor simulating xanthogranulomatous pyelonephritis. (8577559)
1995
28
Amyloidosis secondary to xanthogranulomatous pyelonephritis: an unusual case. (7646703)
1995
29
Paediatric xanthogranulomatous pyelonephritis in a horseshoe kidney. (8032851)
1994
30
Complications of xanthogranulomatous pyelonephritis (XGP). (7793352)
1994
31
From the Archives of the AFIP. Xanthogranulomatous pyelonephritis. (1852939)
1991
32
Xanthogranulomatous pyelonephritis. A report of two cases. (2152092)
1990
33
Xanthogranulomatous pyelonephritis. (2819382)
1989
34
Mucin secreting adenocarcinoma of pelvis with xanthogranulomatous pyelonephritis (a case report). (2853135)
1987
35
Xanthogranulomatous pyelonephritis. A review with 2 case reports. (3750578)
1986
36
Ultrasound and CT in renal parenchymal malakoplakia: report of a case with previous xanthogranulomatous pyelonephritis. (3904893)
1985
37
Association of xanthogranulomatous pyelonephritis with small renal cell carcinoma. Case report and review of the literature. (6698091)
1984
38
Atypical presentation of xanthogranulomatous pyelonephritis: diagnosis by ultrasonography and fine needle aspiration biopsy. (6726970)
1984
39
Xanthogranulomatous pyelonephritis associated with renal carcinoma. (7411698)
1980
40
Focal xanthogranulomatous pyelonephritis in adulthood. (7366060)
1980
41
Xanthogranulomatous pyelonephritis (XGP): a local disease with systemic manifestations. Report of 23 patients and review of the literature. (431402)
1979
42
Xanthogranulomatous pyelonephritis masquerading as occult malignancy. (354158)
1978
43
Diffuse xanthogranulomatous pyelonephritis in children: an unrecognized variant. (904052)
1977
44
New thoughts concerning xanthogranulomatous pyelonephritis (X-P). (1200208)
1975
45
Xanthogranulomatous pyelonephritis and agglutination of erythrocytes. (4544276)
1974
46
Xanthogranulomatous pyelonephritis. (5011396)
1972
47
Xanthogranulomatous pyelonephritis. (5039761)
1972
48
Xanthogranulomatous pyelonephritis: 2 case reports. (5343473)
1969
49
Tumefactive xanthogranulomatous pyelonephritis. (13989643)
1963
50
Xanthogranulomatous pyelonephritis. (14422986)
1959

Genetic Variations for Xanthogranulomatous Pyelonephritis

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Expression for genes affiliated with Xanthogranulomatous Pyelonephritis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Xanthogranulomatous Pyelonephritis

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Pathways for genes affiliated with Xanthogranulomatous Pyelonephritis

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55SinoBiological
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Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5MUC1, EGF

Compounds for genes affiliated with Xanthogranulomatous Pyelonephritis

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44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 49PharmGKB, 24HMDB
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Compounds related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

(show all 20)
idCompoundScoreTop Affiliating Genes
1shikonin449.8EGF, CCL2
2ro 31 8220449.8CCL2, EGF
3hcec449.8CCL2, EGF
4go 697644 5910.7EGF, CCL2
5pertussis449.6CCL2, EGF
6ang ii449.6CCL2, EGF
7mifepristone44 59 28 1112.4MUC1, EGF, CCL2
8hirudin449.4CCL2, SCG5
95fluorouracil449.4CCL2, EGF, MUC1
10agar449.3MUC1, EGF, CCL2
11trastuzumab44 49 1111.2MUC1, EGF
12actinomycin d449.2MUC1, EGF, CCL2
13cisplatin44 49 59 1112.0ERCC5, MUC1, EGF, CCL2
14polysaccharide449.0MUC1, SCG5, CCL2
15butyrate449.0SCG5, EGF, MUC1
16paraffin448.8MUC1, SCG5, CCL2
17thymidine44 249.7MUC1, EGF, SCG5
18testosterone44 59 11 2411.6CCL2, SCG5, EGF, MUC1
19glutamine448.6CCL2, SCG5, EGF
20dexamethasone44 49 28 1111.5MUC1, EGF, SCG5, CCL2

GO Terms for genes affiliated with Xanthogranulomatous Pyelonephritis

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Products for genes affiliated with Xanthogranulomatous Pyelonephritis

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Sources for Xanthogranulomatous Pyelonephritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
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36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
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50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
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