MCID: XNT001
MIFTS: 38

Xanthogranulomatous Pyelonephritis malady

Summaries for Xanthogranulomatous Pyelonephritis

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32MalaCards
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MalaCards: Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to adenocarcinoma and pyelonephritis. An important gene associated with Xanthogranulomatous Pyelonephritis is ERCC5 (excision repair cross-complementing rodent repair deficiency, complementation group 5), and among its related pathways is EGFR Signaling Pathway. The compounds shikonin and ro 31 8220 have been mentioned in the context of this disorder. Affiliated tissues include kidney, colon and liver, and related mouse phenotypes are digestive/alimentary and liver/biliary system.

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

xanthogranulomatous pyelonephritis 8 10
pyelonephritis, xanthogranulomatous 60


External Ids:

Disease Ontology8 DOID:11401
SNOMED-CT56 197777006, 38898003
MeSH34 D011705

Related Diseases for Xanthogranulomatous Pyelonephritis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to xanthogranulomatous pyelonephritis

Clinical Features for Xanthogranulomatous Pyelonephritis

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Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Xanthogranulomatous Pyelonephritis

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Anatomical Context for Xanthogranulomatous Pyelonephritis

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32MalaCards
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MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

32
Kidney, Colon, Liver, Bone, Spinal cord, Lung, Monocytes

Animal Models for Xanthogranulomatous Pyelonephritis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.7CCL2, EGF, MUC1, ERCC5
2MP:00053708.1SCG5, MUC1, ERCC5, CCL2
3MP:00107717.8EGF, ERCC5, MUC1, CCL2, SCG5

Publications for Xanthogranulomatous Pyelonephritis

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50PubMed
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Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50)    (show all 421)
idTitleAuthorsYear
1
Focal xanthogranulomatous pyelonephritis presenting as renal tumor. (23580815)
2013
2
Girl with xanthogranulomatous pyelonephritis and bronchiectasis: case report. (23679176)
2013
3
Xanthogranulomatous pyelonephritis-mimicking renal mass in 5-month-old child. (22342409)
2012
4
Fever of unknown origin (FUO) and a renal mass: renal cell carcinoma, renal tuberculosis, renal malakoplakia, or xanthogranulomatous pyelonephritis? (22658892)
2012
5
Laparoscopic nephrectomy in xanthogranulomatous pyelonephritis: 7-year single-surgeon outcome. (21862116)
2011
6
Surgically discovered xanthogranulomatous pyelonephritis invading inferior vena cava with coexisting renal cell carcinoma. (19151892)
2009
7
Xanthogranulomatous pyelonephritis: clinical experience with 41 cases. (18308077)
2008
8
Laparoscopic nephrectomy for xanthogranulomatous pyelonephritis in childhood: the way forward. (18631926)
2008
9
Renal parenchymal malacoplakia: a different stage of xanthogranulomatous pyelonephritis? (17618870)
2007
10
Laparoscopic nephrectomy for xanthogranulomatous pyelonephritis in the absence of kidney stones or clinical urinary infection. (18097329)
2007
11
Xanthogranulomatous pyelonephritis characterized on PET/CT. (16237295)
2005
12
Xanthogranulomatous pyelonephritis--the "great imitator" justifies its name. (12002363)
2002
13
Unusual presentation of xanthogranulomatous pyelonephritis. (11445489)
2001
14
Images in clinical medicine. Xanthogranulomatous pyelonephritis. (10824076)
2000
15
Xanthogranulomatous pyelonephritis--a pseudo-neoplastic disease. (10227452)
1999
16
Focal xanthogranulomatous pyelonephritis in a teenager. (9717648)
1998
17
Is diffuse xanthogranulomatous pyelonephritis a contraindication to retroperitoneoscopic nephroureterectomy? A case report. (9799147)
1998
18
Xanthogranulomatous pyelonephritis with bilateral nephrocutaneous fistulae. (9313324)
1997
19
Focal xanthogranulomatous pyelonephritis in a young child. (7936803)
1994
20
Xanthogranulomatous pyelonephritis in childhood: pre-operative diagnosis is possible. (8298903)
1994
21
Case report: xanthogranulomatous pyelonephritis presenting as a cutaneous fistula. (8514485)
1993
22
Xanthogranulomatous pyelonephritis: King Faisal Specialist Hospital experience. (17587985)
1993
23
A case of xanthogranulomatous pyelonephritis in a child. (8139141)
1993
24
Coexisting renal cell carcinoma and xanthogranulomatous pyelonephritis in a chronic calculous disease. (1413313)
1992
25
A case of xanthogranulomatous pyelonephritis successfully treated operatively. (1369515)
1992
26
Xanthogranulomatous pyelonephritis with nephrocutaneous fistula at the knee. (2070215)
1991
27
Perinephric xanthogranulomatous pyelonephritis simulating a renal or retroperitoneal tumor on X-ray CT and angiography. (2587801)
1989
28
Xanthogranulomatous pyelonephritis in childhood. Further case reports from Iraq. (3230545)
1988
29
Bilateral metachronous xanthogranulomatous pyelonephritis in end-stage renal failure. (3787879)
1986
30
Computed tomography of xanthogranulomatous pyelonephritis presenting as a flank mass. (4053662)
1985
31
Xanthogranulomatous pyelonephritis caused by methicillin-resistant Staphylococcus aureus. (6560982)
1984
32
Computed tomography in xanthogranulomatous pyelonephritis. (6529954)
1984
33
An unusual case of xanthogranulomatous pyelonephritis. (6722439)
1984
34
Biliary obstruction due to xanthogranulomatous pyelonephritis. (7120490)
1982
35
Xanthogranulomatous pyelonephritis. An immunohistochemical and ultrastructural study on the occurrence of bacteria and bacterial antigen. (7324298)
1981
36
Xanthogranulomatous pyelonephritis: detailed analysis of 29 cases and a brief discussion of atypical presentations. (7288929)
1981
37
Bilateral xanthogranulomatous pyelonephritis. (7470808)
1981
38
Xanthogranulomatous pyelonephritis: a case report. (539123)
1979
39
Current cases & concepts: xanthogranulomatous pyelonephritis. (262209)
1979
40
Xanthogranulomatous pyelonephritis in childhood. Report of three cases and a review of the literature. (372908)
1979
41
Xanthogranulomatous pyelonephritis-presentation as acute renal failure in a child with a solitary kidney. (673100)
1978
42
Re: xanthogranulomatous pyelonephritis in childhood. (839616)
1977
43
Xanthogranulomatous pyelonephritis: with emphasis on angiographic findings. (1064766)
1976
44
Xanthogranulomatous pyelonephritis in childhood. (950713)
1976
45
Localized xanthogranulomatous pyelonephritis with preservation of the involved kidney: An unusual variation. (4604703)
1974
46
Xanthogranulomatous pyelonephritis: an unusual case. (5116290)
1971
47
Xanthogranulomatous pyelonephritis. (5705953)
1968
48
Xanthogranulomatous pyelonephritis. (5725273)
1968
49
Xanthogranulomatous pyelonephritis. (5917484)
1966
50
Tumefactive xanthogranulomatous pyelonephritis. (13486398)
1957

Genetic Variations for Xanthogranulomatous Pyelonephritis

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Expression for genes affiliated with Xanthogranulomatous Pyelonephritis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Xanthogranulomatous Pyelonephritis

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Pathways for genes affiliated with Xanthogranulomatous Pyelonephritis

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55SinoBiological
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Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5MUC1, EGF

Compounds for genes affiliated with Xanthogranulomatous Pyelonephritis

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44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank, 49PharmGKB, 24HMDB
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Compounds related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

(show all 20)
idCompoundScoreTop Affiliating Genes
1shikonin449.8CCL2, EGF
2ro 31 8220449.8EGF, CCL2
3hcec449.8CCL2, EGF
4go 697644 5910.7EGF, CCL2
5pertussis449.6EGF, CCL2
6ang ii449.6EGF, CCL2
7mifepristone44 59 28 1112.4MUC1, EGF, CCL2
8hirudin449.4SCG5, CCL2
95fluorouracil449.4MUC1, CCL2, EGF
10agar449.3CCL2, MUC1, EGF
11trastuzumab44 49 1111.2MUC1, EGF
12actinomycin d449.2MUC1, EGF, CCL2
13cisplatin44 49 59 1112.0ERCC5, CCL2, EGF, MUC1
14polysaccharide449.0MUC1, SCG5, CCL2
15butyrate449.0SCG5, EGF, MUC1
16paraffin448.8CCL2, MUC1, SCG5
17thymidine44 249.7MUC1, SCG5, EGF
18testosterone44 59 11 2411.6SCG5, CCL2, EGF, MUC1
19glutamine448.6SCG5, EGF, CCL2
20dexamethasone44 49 28 1111.5SCG5, EGF, CCL2, MUC1

GO Terms for genes affiliated with Xanthogranulomatous Pyelonephritis

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Products for genes affiliated with Xanthogranulomatous Pyelonephritis

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Sources for Xanthogranulomatous Pyelonephritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet