MCID: XNT001
MIFTS: 41

Xanthogranulomatous Pyelonephritis malady

Nephrological diseases category
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Summaries for Xanthogranulomatous Pyelonephritis

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33MalaCards
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MalaCards: Xanthogranulomatous Pyelonephritis, also known as pyelonephritis, xanthogranulomatous, is related to pneumonia and pyelonephritis. An important gene associated with Xanthogranulomatous Pyelonephritis is MUC1 (mucin 1, cell surface associated), and among its related pathways are EGFR Signaling Pathway and Development EGFR signaling pathway. The compounds trastuzumab and progestin have been mentioned in the context of this disorder. Affiliated tissues include kidney, colon and liver, and related mouse phenotypes are normal and liver/biliary system.

Aliases & Classifications for Xanthogranulomatous Pyelonephritis

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8Disease Ontology, 10DISEASES, 62UMLS, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Nephrological diseases


Aliases & Descriptions:

xanthogranulomatous pyelonephritis 8 10
pyelonephritis, xanthogranulomatous 62


External Ids:

Disease Ontology8 DOID:11401
SNOMED-CT58 38898003, 197777006
MeSH35 D011705

Related Diseases for Xanthogranulomatous Pyelonephritis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Xanthogranulomatous Pyelonephritis:



Diseases related to xanthogranulomatous pyelonephritis

Symptoms for Xanthogranulomatous Pyelonephritis

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Drugs & Therapeutics for Xanthogranulomatous Pyelonephritis

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Search NIH Clinical Center for Xanthogranulomatous Pyelonephritis

Genetic Tests for Xanthogranulomatous Pyelonephritis

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Anatomical Context for Xanthogranulomatous Pyelonephritis

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33MalaCards
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MalaCards organs/tissues related to Xanthogranulomatous Pyelonephritis:

33
Kidney, Colon, Liver, Bone, Spinal cord, Lung, Monocytes

Animal Models for Xanthogranulomatous Pyelonephritis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Xanthogranulomatous Pyelonephritis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.6EGF, CCL2, MUC1
2MP:00053708.4MUC1, CCL2, ERCC5
3MP:00053918.3EGF, CCL2, MUC1
4MP:00053818.1EGF, ERCC5, CCL2, MUC1
5MP:00107718.0EGF, ERCC5, CCL2, MUC1

Publications for Xanthogranulomatous Pyelonephritis

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52PubMed
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Articles related to Xanthogranulomatous Pyelonephritis:

(show top 50)    (show all 417)
idTitleAuthorsYear
1
Renal replacement lipomatosis with coexistent papillary renal cell carcinoma, renal tubulopapillary adenomatosis, and xanthogranulomatous pyelonephritis: an extremely rare association and possible pathogenetic correlation. (23801477)
2013
2
Nephrobronchial fistula complicating neglected nephrolithiasis and xanthogranulomatous pyelonephritis. (21566318)
2011
3
Xanthogranulomatous pyelonephritis in a horse-shoe kidney. (20427880)
2010
4
Puzzles in practice. Xanthogranulomatous pyelonephritis (XGP). (21084798)
2010
5
Xanthogranulomatous pyelonephritis in an adolescent. (20579704)
2010
6
Xanthogranulomatous pyelonephritis infiltrating the liver. (18926204)
2008
7
Renal parenchymal malacoplakia: a different stage of xanthogranulomatous pyelonephritis? (17618870)
2007
8
Images in emergency medicine. Xanthogranulomatous pyelonephritis. (17709049)
2007
9
Xanthogranulomatous pyelonephritis is associated with higher tissue expression of monocyte chemotactic protein-1. (17968796)
2007
10
Xanthogranulomatous pyelonephritis. (16481231)
2006
11
Hand-assisted laparoscopic nephrectomy for xanthogranulomatous pyelonephritis with nephrocutaneous fistula after failed flank exploration. (16921310)
2006
12
Co-existent massive renal replacement lipomatosis and xanthogranulomatous pyelonephritis--a case report. (15025379)
2003
13
Xanthogranulomatous pyelonephritis in a dysplastic kidney with reflux associated with posterior urethral valves. (11832763)
2002
14
Intra-abdominal actinomycosis with hepatic pseudotumor and xanthogranulomatous pyelonephritis in a 6-y-old boy. (11515770)
2001
15
Xanthogranulomatous pyelonephritis: urinary and fine needle aspiration cytology. (9684612)
1998
16
Focal xanthogranulomatous pyelonephritis in a teenager. (9717648)
1998
17
Xanthogranulomatous pyelonephritis presenting as a psoas abscess in a child. (8800918)
1996
18
Xanthogranulomatous pyelonephritis associated with transitional cell carcinoma of the renal pelvis. (8961496)
1996
19
Xanthogranulomatous pyelonephritis in pediatric patients. (7752369)
1995
20
Focal xanthogranulomatous pyelonephritis in a young child. (7936803)
1994
21
Image interpretation session. Focal xanthogranulomatous pyelonephritis. (1734468)
1992
22
Xanthogranulomatous pyelonephritis with nephrocutaneous fistula at the knee. (2070215)
1991
23
Xanthogranulomatous pyelonephritis. A report of two cases. (2152092)
1990
24
Xanthogranulomatous pyelonephritis in children and adults--an 8 year study. (2091999)
1990
25
Xanthogranulomatous pyelonephritis--(a clinicopathological study of 15 cases) (2490367)
1989
26
Xanthogranulomatous pyelonephritis. A reappraisal and immunohistochemical study. (3345125)
1988
27
Ultrasonography and needle aspiration in diagnosis of xanthogranulomatous pyelonephritis. (3544457)
1987
28
Xanthogranulomatous pyelonephritis with reno-colonic and cutaneous fistulae. (3676680)
1987
29
Serendipitous diagnosis of childhood xanthogranulomatous pyelonephritis in a child with osteomyelitis. (3550670)
1987
30
Generalized amyloidosis secondary to xanthogranulomatous pyelonephritis. (3816863)
1986
31
Xanthogranulomatous pyelonephritis in children. (3968740)
1985
32
Computed tomography of xanthogranulomatous pyelonephritis presenting as a flank mass. (4053662)
1985
33
Xanthogranulomatous pyelonephritis with bilharzial ureteric obstruction. (6653472)
1983
34
Biliary obstruction due to xanthogranulomatous pyelonephritis. (7120490)
1982
35
Diffuse xanthogranulomatous pyelonephritis: analysis by computed tomography and sonography. (7101607)
1982
36
Xanthogranulomatous pyelonephritis associated with renal carcinoma. (7411698)
1980
37
Xanthogranulomatous pyelonephritis: a report of 40 cases. (7228606)
1980
38
The underestimated hazards of xanthogranulomatous pyelonephritis. (534821)
1979
39
Xanthogranulomatous pyelonephritis (XGP): a local disease with systemic manifestations. Report of 23 patients and review of the literature. (431402)
1979
40
Bilateral diffuse xanthogranulomatous pyelonephritis. (465976)
1979
41
Xanthogranulomatous pyelonephritis in children. (320349)
1977
42
Xanthogranulomatous pyelonephritis. (562462)
1977
43
Xanthogranulomatous pyelonephritis. Angiographic evaluation. (4591220)
1974
44
Peripartum hepatic dysfunction and xanthogranulomatous pyelonephritis. (4576472)
1973
45
Xanthogranulomatous pyelonephritis: a comprehensive review with report of 4 additional cases. (5100861)
1971
46
Xanthogranulomatous pyelonephritis. (5804197)
1969
47
Xanthogranulomatous pyelonephritis. A case report with angiographic findings. (5931830)
1966
48
Xanthogranulomatous pyelonephritis. (5905474)
1966
49
XANTHOGRANULOMATOUS PYELONEPHRITIS: CONFUSION WITH RENAL CARCINOMA. (14217946)
1964
50
XANTHOGRANULOMATOUS PYELONEPHRITIS. (14134284)
1963

Variations for Xanthogranulomatous Pyelonephritis

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Expression for genes affiliated with Xanthogranulomatous Pyelonephritis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Xanthogranulomatous Pyelonephritis

Search GEO for disease gene expression data for Xanthogranulomatous Pyelonephritis.

Pathways for genes affiliated with Xanthogranulomatous Pyelonephritis

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50PathCards, 57SinoBiological, 60Thomson Reuters, 53QIAGEN, 55Reactome
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Pathways related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4EGF, MUC1
2
Show member pathways
Development ERBB family signaling60
Development GDNF family signaling60
9.4EGF, MUC1
3
Show member pathways
8.6EGF, CCL2, MUC1

Compounds for genes affiliated with Xanthogranulomatous Pyelonephritis

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45Novoseek, 51PharmGKB, 11DrugBank, 3BitterDB, 61Tocris Bioscience, 29IUPHAR, 24HMDB
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Compounds related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

(show all 37)
idCompoundScoreTop Affiliating Genes
1trastuzumab45 51 1111.8MUC1, EGF
2progestin459.8EGF, MUC1
3gemcitabine45 51 1111.8MUC1, EGF
4hydrocortisone45 3 61 1112.8EGF, MUC1
5dihydrotestosterone45 29 24 1112.7EGF, MUC1
6matrigel459.7EGF, MUC1
712-o-tetradecanoylphorbol 13-acetate459.6MUC1, EGF
8butyrate459.5EGF, MUC1
9shikonin459.5EGF, CCL2
10hcec459.5EGF, CCL2
11ro 31 8220459.5EGF, CCL2
12go 697645 6110.5EGF, CCL2
13ang ii459.5CCL2, EGF
14pertussis459.5CCL2, EGF
15tamoxifen45 51 29 1112.5MUC1, EGF
16cytochalasin d45 6110.5EGF, CCL2
17egcg459.5CCL2, EGF
18mg 13245 6110.4EGF, CCL2
19tgf beta1459.4CCL2, EGF
20herbimycin a45 6110.4EGF, CCL2
21formaldehyde45 2410.4CCL2, MUC1
22gnrh459.4CCL2, EGF
23ribonucleic acid459.4MUC1, CCL2
24sb 20358045 6110.3EGF, CCL2
25polysaccharide459.1CCL2, MUC1
26wortmannin459.1EGF, CCL2
27pd 98,059459.0EGF, CCL2
28mifepristone45 29 61 1112.0MUC1, CCL2, EGF
295fluorouracil459.0EGF, CCL2, MUC1
30agar459.0MUC1, CCL2, EGF
31actinomycin d459.0MUC1, CCL2, EGF
32testosterone45 61 24 1112.0EGF, CCL2, MUC1
33dexamethasone45 51 29 1112.0EGF, CCL2, MUC1
34vegf459.0MUC1, CCL2, EGF
35ly294002458.8EGF, CCL2
36serine458.8EGF, CCL2, MUC1
37cisplatin45 51 61 1111.4EGF, ERCC5, CCL2, MUC1

GO Terms for genes affiliated with Xanthogranulomatous Pyelonephritis

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16Gene Ontology
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Biological processes related to Xanthogranulomatous Pyelonephritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1angiogenesisGO:0015259.1EGF, CCL2

Products for genes affiliated with Xanthogranulomatous Pyelonephritis

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Sources for Xanthogranulomatous Pyelonephritis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet