MCID: XNT009
MIFTS: 23

Xanthoma Disseminatum malady

Skin category

Summaries for Xanthoma Disseminatum

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Xanthoma disseminatum (also known as \"Disseminated xanthosiderohistiocytosis\" and \"Montgomery... more...

MalaCards: Xanthoma Disseminatum, also known as montgomery syndrome, is related to xanthomatosis and macroglobulinemia, and has symptoms including follicular/erythematous/edematous papules/milium, osteolysis/osteoclasia/bone destruction/erosions and enanthema/aphtosa/aphta/leukoplakia. An important gene associated with Xanthoma Disseminatum is F13A1 (coagulation factor XIII, A1 polypeptide). Affiliated tissues include bone marrow, skeletal muscle and skin.

Aliases & Classifications for Xanthoma Disseminatum

Sources:
49Orphanet, 61UMLS, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin


Aliases & Descriptions:

xanthoma disseminatum 49 61
montgomery syndrome 49


External Ids:

ICD10 via Orphanet26 D76.3
SNOMED-CT via Orphanet58 399970005
UMLS via Orphanet62 C0043322

Related Diseases for Xanthoma Disseminatum

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Xanthoma Disseminatum via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1xanthomatosis10.5
2macroglobulinemia10.2
3bronchiectasis10.2
4urticaria pigmentosa10.2
5urticaria10.2

Graphical network of diseases related to Xanthoma Disseminatum:



Diseases related to xanthoma disseminatum

Clinical Features for Xanthoma Disseminatum

Sources:
49Orphanet
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Symptoms:

49 (see all 4)
  • follicular/erythematous/edematous papules/milium
  • osteolysis/osteoclasia/bone destruction/erosions
  • enanthema/aphtosa/aphta/leukoplakia
  • diabetes insipidus

Drugs & Therapeutics for Xanthoma Disseminatum

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Xanthoma Disseminatum

Anatomical Context for Xanthoma Disseminatum

Sources:
33MalaCards
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MalaCards organs/tissues related to Xanthoma Disseminatum:

33
Bone marrow, Skeletal muscle, Skin

Animal Models for Xanthoma Disseminatum or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Xanthoma Disseminatum

Sources:
51PubMed
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Articles related to Xanthoma Disseminatum:

(show top 50)    (show all 79)
idTitleAuthorsYear
1
Xanthoma disseminatum: a red herring xanthomatosis. (23442474)
2013
2
A Case of Xanthoma Disseminatum: Evaluation and Monitoring by (18) F-fluorodeoxyglucose (FDG) PET/CT. (24329687)
2013
3
Intertriginous orange-to-brownish papules and plaques: a quiz. Xanthoma disseminatum. (23165822)
2013
4
Successful treatment of xanthoma disseminatum with combined lipid lowering agents. (22879732)
2012
5
Xanthoma disseminatum: effective therapy with 2-chlorodeoxyadenosine in a case series. (21173305)
2011
6
A case of xanthoma disseminatum with spontaneous resolution over 10 years: review of the literature on long-term follow-up. (21613781)
2011
7
Retinal manifestations in a patient with xanthoma disseminatum (non-langerhans cell histiocytosis). (21484660)
2011
8
Successful treatment of xanthoma disseminatum with simvastatin. (21592199)
2011
9
Xanthoma disseminatum in a pair of blind, deaf male twins. (22363847)
2011
10
Xanthoma disseminatum with atypical histochemical features. (20236289)
2010
11
Xanthoma disseminatum with intracranial involvement: case report and literature review. (20465646)
2010
12
A Case of Xanthoma Disseminatum Accentuating over the Eyelids. (20711279)
2010
13
Xanthoma disseminatum with koebnerized pearly penile lesions in an Indian man. (19702989)
2009
14
Xanthoma disseminatum in a black African woman. (18986445)
2008
15
Xanthoma disseminatum in a child with cranial bone involvement. (18391701)
2008
16
Inflammation and lipid accumulation in xanthoma disseminatum: Therapeutic considerations. (18191707)
2008
17
Xanthoma disseminatum with bilateral epibulbar involvement. (15767078)
2005
18
Hypopituitarism and rare dermatological diseases: an intriguing case of xanthoma disseminatum. (15963073)
2005
19
Xanthoma disseminatum: case report. (15588563)
2004
20
Xanthoma disseminatum with large plaques confined to the back, pulmonary involvement and multiple intestinal xanthomas. (15057010)
2004
21
Treatment of xanthoma disseminatum with cyclophosphamide. (14996108)
2004
22
Xanthoma disseminatum: a rare intracranial mass. (12533335)
2003
23
Xanthoma disseminatum. (12492986)
2002
24
Bilateral laryngeal pseudoparalysis in xanthoma disseminatum treated by endoscopic laser medial arytenoidectomy. (11269772)
2001
25
Cerebrocutaneous xanthoma disseminatum and disseminated demyelinating encephalomyelitis. (10965168)
2000
26
Xanthoma disseminatum with multi-system involvement and fatal outcome. (10461659)
1999
27
Treatment of cutaneous lesions of xanthoma disseminatum with a CO2 laser. (10594575)
1999
28
Xanthoma disseminatum with marked mucocutaneous involvement]. (9835892)
1998
29
The various clinical patterns of xanthoma disseminatum. Considerations on seven cases and review of the literature. (7894090)
1995
30
Generalized eruptive histiocytoma evolving into xanthoma disseminatum in a 4-year-old boy. (7662578)
1995
31
Xanthoma disseminatum, a rare cause of diabetes insipidus. (8445037)
1993
32
Xanthoma disseminatum: a rare normolipemic xanthomatosis. (8481626)
1993
33
Histologic and immunohistochemical study comparing xanthoma disseminatum and histiocytosis X. (1519935)
1992
34
Xanthoma disseminatum. (1634296)
1992
35
Xanthoma disseminatum: a case with extensive mucous membrane involvement. (1894788)
1991
36
Xanthoma disseminatum. (2269570)
1990
37
Xanthoma disseminatum with progressive involvement of the central nervous and hepatobiliary systems. (2394852)
1990
38
Xanthoma disseminatum: a rare condition with non-X, non-lipid cutaneous histiocytopathy. (3261744)
1988
39
Xanthoma disseminatum. An unusual histiocytosis syndrome. (3140686)
1988
40
Juvenile xanthogranulomas and xanthoma disseminatum--variations on a single theme. (3088071)
1986
41
Xanthoma disseminatum: an unusual cause of facial and limb deformity. (6611781)
1983
42
Xanthoma disseminatum. Clinical, metabolic, pathologic, and radiologic aspects. (889337)
1977
43
Xanthoma disseminatum and multiple myeloma. (4420882)
1974
44
Xanthoma disseminatum. (4855434)
1974
45
Xanthoma disseminatum. Clinical and laboratory observations over a ten year period. (5414357)
1970
46
A NECROPSY REPORT OF A PATIENT WITH XANTHOMA DISSEMINATUM. (14319647)
1965
47
Tissue lipid patterns in a case of xanthoma disseminatum. (13971828)
1963
48
Reticulohistiocytosis: resembling xanthoma disseminatum. (13786565)
1961
49
Xanthoma disseminatum; an unusual form with extension of xanthomatous changes into muscle. (14877294)
1952
50
Xanthoma disseminatum. (20287977)
1947

Genetic Variations for Xanthoma Disseminatum

Expression for genes affiliated with Xanthoma Disseminatum

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Xanthoma Disseminatum

Search GEO for disease gene expression data for Xanthoma Disseminatum.

Pathways for genes affiliated with Xanthoma Disseminatum

Compounds for genes affiliated with Xanthoma Disseminatum

GO Terms for genes affiliated with Xanthoma Disseminatum

Products for genes affiliated with Xanthoma Disseminatum

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Sources for Xanthoma Disseminatum

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet