MCID: YLL002
MIFTS: 63

Yellow Fever

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Yellow Fever

MalaCards integrated aliases for Yellow Fever:

Name: Yellow Fever 12 72 49 55 51 3 41 14 69
Jungle Yellow Fever 12 69
Urban Yellow Fever 12 69
Yf 49 55
Sylvatic Yellow Fever 12
Yellow Fever, Sylvan 12
Bronze John 55
Yellow Jack 55

Characteristics:

Orphanet epidemiological data:

55
yellow fever
Prevalence: <1/1000000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 55  
Rare infectious diseases


Summaries for Yellow Fever

Disease Ontology : 12 A viral infectious disease that results_in infection, has material basis in Yellow fever virus, which is transmitted_by Aedes, transmitted_by Haemagogus, or transmitted_by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood.

MalaCards based summary : Yellow Fever, also known as jungle yellow fever, is related to encephalitis and japanese encephalitis, and has symptoms including fever, muscle pain and backache. An important gene associated with Yellow Fever is EIF2AK4 (Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Vaccines and Vitamin A have been mentioned in the context of this disorder. Affiliated tissues include liver, skin and t cells, and related phenotypes are hematopoietic system and homeostasis/metabolism

CDC : 3 Yellow fever virus is found in tropical and subtropical areas in South America and Africa. The virus is transmitted to people by the bite of an infected mosquito. Yellow fever is a very rare cause of illness in U.S. travelers. Illness ranges in severity from a self-limited febrile illness to severe liver disease with bleeding. 

Wikipedia : 72 Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever,... more...

Related Diseases for Yellow Fever

Diseases related to Yellow Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
# Related Disease Score Top Affiliating Genes
1 encephalitis 30.8 CCL5 CCR5 RSAD2
2 japanese encephalitis 29.8 CCL5 IFNB1 STAT1
3 venezuelan equine encephalitis 29.3 IFNB1 IRF7 STAT1
4 influenza 28.8 CCL5 IFNB1 IRF7 RSAD2 TLR9
5 dermatitis, atopic 28.7 CCL5 IL17A IL5 TLR9
6 malaria 28.7 CCL5 IL17A IL1RN IL5 TLR9
7 autoimmune disease 28.5 IL17A IL1RN IL5 TLR9
8 multiple sclerosis 27.4 CCL5 CCR5 IFNB1 IL17A IL5 STAT1
9 hemorrhagic fever 11.1
10 kyasanur forest disease 10.8
11 whiplash 10.5 CCL5 CCR5
12 orofacial granulomatosis 10.4 CCL5 CCR5
13 cow milk allergy 10.4 CCR5 IL5
14 chronic eosinophilic pneumonia 10.4 CCL5 IL5
15 apple allergy 10.4 IL5 SCP2
16 gastrointestinal allergy 10.4 CCL5 IL5
17 chronic conjunctivitis 10.3 CCL5 IL5
18 status asthmaticus 10.3 CCL5 IL5
19 kimura disease 10.3 CCL5 IL5
20 folliculitis 10.3 CCL5 IL5
21 west nile virus 10.2 CCR5 OAS1 RSAD2
22 west nile encephalitis 10.2 OAS1 TLR9
23 immune-complex glomerulonephritis 10.2 CCR5 TLR9
24 vernal keratoconjunctivitis 10.2 CCL5 IL5
25 meningococcemia 10.1 CCL5 IL1RN
26 hepatitis 10.1
27 human immunodeficiency virus infectious disease 10.1 CCL5 CCR5 TLR9
28 chronic nk-cell lymphocytosis 10.1 CCL5 CCR5
29 respiratory syncytial virus infectious disease 10.1 CCL5 IFNB1 IL5
30 leukoencephalopathy with dystonia and motor neuropathy 10.1
31 st. louis encephalitis 10.1
32 measles 10.1
33 nut allergy 10.1 IL5 SCP2 TLR9
34 filariasis 10.1 CCL5 IL5 TLR9
35 bronchiolitis 10.1 CCL5 IL5 TLR9
36 noonan syndrome 5 10.0
37 dengue virus 10.0
38 zika fever 10.0 IFNB1 STAT1
39 rhinitis 10.0 CCL5 IL5 TLR9
40 pneumonia 10.0 CCL5 IL5 TLR9
41 kaposi sarcoma 10.0 CCR5 IFNB1 IRF7
42 aging 10.0
43 chikungunya 10.0
44 hepatitis a 10.0
45 egg allergy 10.0
46 neuronitis 10.0
47 smallpox 10.0
48 anterior scleritis 10.0 IL1RN IL5
49 lung disease 10.0 CCL5 IL5 TLR9
50 noonan syndrome 3 9.9

Graphical network of the top 20 diseases related to Yellow Fever:



Diseases related to Yellow Fever

Symptoms & Phenotypes for Yellow Fever

Symptoms:

12
  • fever
  • muscle pain
  • backache
  • headache
  • shivers
  • loss of appetite
  • jaundice
  • bleeding from the mouth

Human phenotypes related to Yellow Fever:

55 31 (show all 29)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 renal insufficiency 55 31 occasional (7.5%) Occasional (29-5%) HP:0000083
2 proteinuria 55 31 frequent (33%) Frequent (79-30%) HP:0000093
3 nephropathy 55 31 occasional (7.5%) Occasional (29-5%) HP:0000112
4 photophobia 55 31 occasional (7.5%) Occasional (29-5%) HP:0000613
5 jaundice 55 31 frequent (33%) Frequent (79-30%) HP:0000952
6 lethargy 55 31 occasional (7.5%) Occasional (29-5%) HP:0001254
7 meningitis 55 31 occasional (7.5%) Occasional (29-5%) HP:0001287
8 congestive heart failure 55 31 occasional (7.5%) Occasional (29-5%) HP:0001635
9 dehydration 55 31 occasional (7.5%) Occasional (29-5%) HP:0001944
10 fever 55 31 hallmark (90%) Very frequent (99-80%) HP:0001945
11 diarrhea 55 31 frequent (33%) Frequent (79-30%) HP:0002014
12 nausea and vomiting 55 31 frequent (33%) Frequent (79-30%) HP:0002017
13 abdominal pain 55 31 frequent (33%) Frequent (79-30%) HP:0002027
14 anorexia 55 31 frequent (33%) Frequent (79-30%) HP:0002039
15 hypothermia 55 31 occasional (7.5%) Occasional (29-5%) HP:0002045
16 malignant hyperthermia 55 31 occasional (7.5%) Occasional (29-5%) HP:0002047
17 gastrointestinal hemorrhage 55 31 frequent (33%) Frequent (79-30%) HP:0002239
18 headache 55 31 hallmark (90%) Very frequent (99-80%) HP:0002315
19 encephalitis 55 31 occasional (7.5%) Occasional (29-5%) HP:0002383
20 hypotension 55 31 occasional (7.5%) Occasional (29-5%) HP:0002615
21 arthralgia 55 31 frequent (33%) Frequent (79-30%) HP:0002829
22 myalgia 55 31 frequent (33%) Frequent (79-30%) HP:0003326
23 spontaneous abortion 55 31 frequent (33%) Frequent (79-30%) HP:0005268
24 cardiorespiratory arrest 55 31 occasional (7.5%) Occasional (29-5%) HP:0006543
25 acute hepatic failure 55 31 occasional (7.5%) Occasional (29-5%) HP:0006554
26 arrhythmia 55 31 occasional (7.5%) Occasional (29-5%) HP:0011675
27 oliguria 55 31 frequent (33%) Frequent (79-30%) HP:0100520
28 chest pain 55 31 frequent (33%) Frequent (79-30%) HP:0100749
29 menometrorrhagia 55 31 frequent (33%) Frequent (79-30%) HP:0400008

MGI Mouse Phenotypes related to Yellow Fever:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 IL17A IL1RN IL5 IRF7 RSAD2 CCL5
2 homeostasis/metabolism MP:0005376 9.73 IL17A IL1RN IL5 IRF7 RSAD2 SCP2
3 immune system MP:0005387 9.4 IL1RN IL5 IRF7 RSAD2 SCP2 CCL5

Drugs & Therapeutics for Yellow Fever

Drugs for Yellow Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
2
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 68-26-8, 11103-57-4 445354
3
Lactitol Investigational Phase 3 585-86-4 3871
4 Heptavalent Pneumococcal Conjugate Vaccine Phase 3,Phase 2
5 Retinol palmitate Phase 3
6 Micronutrients Phase 3
7 Trace Elements Phase 3
8 Vitamins Phase 3
9 Protective Agents Phase 3
10 Antioxidants Phase 3
11 retinol Nutraceutical Phase 3
12
Benzocaine Approved, Investigational Phase 1, Phase 2 1994-09-7, 94-09-7 2337
13 tannic acid Approved, Nutraceutical Phase 1, Phase 2
14 Immunoglobulins Phase 2,Phase 1
15 Antimetabolites Phase 2
16 Antibodies Phase 2,Phase 1
17 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
18 Anticholesteremic Agents Phase 2
19 Hypolipidemic Agents Phase 2
20 Anti-Inflammatory Agents Phase 2
21 Lipid Regulating Agents Phase 2
22
Aluminum sulfate Approved Phase 1 10043-01-3
23
Mannitol Approved, Investigational Phase 1 69-65-8 6251 453
24
Aluminum hydroxide Approved, Investigational Phase 1 21645-51-2
25 Rho(D) Immune Globulin Phase 1
26 gamma-Globulins Phase 1
27 Immunoglobulins, Intravenous Phase 1
28 diuretics Phase 1
29 Natriuretic Agents Phase 1
30
Methotrexate Approved 1959-05-2, 59-05-2 126941
31
leucovorin Approved, Nutraceutical 58-05-9 143 6006
32
Folic Acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
33 Folic Acid Antagonists
34 Nucleic Acid Synthesis Inhibitors
35 Dermatologic Agents
36 Vitamin B Complex
37 Immunosuppressive Agents
38 Antimetabolites, Antineoplastic
39 Antirheumatic Agents
40 Folate Nutraceutical
41 Vitamin B9 Nutraceutical

Interventional clinical trials:

(show all 43)

# Name Status NCT ID Phase Drugs
1 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4 IPV IM Needle;IPV ID Needle;IPV IM Device;IPV ID Device
2 Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali Completed NCT02286895 Phase 4
3 Immunity Period After One Dose of Yellow Fever Vaccine in Adults and Children (Paraiba Study) Recruiting NCT02555072 Phase 4
4 Immunogenicity and Safety of the Yellow Fever Vaccine in HIV Infected Individuals Recruiting NCT03132311 Phase 4
5 Immunogenicity of Co-administered Yellow Fever and Measles, Mumps, and Rubella (MMR) Vaccines Recruiting NCT03368495 Phase 4
6 Immunogenicity and Safety of Fractional Doses of Yellow Fever Vaccines (YEFE) Active, not recruiting NCT02991495 Phase 4
7 Study of Yellow Fever Vaccine Administered With Tetravalent Dengue Vaccine in Healthy Toddlers Completed NCT01436396 Phase 3
8 A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults Completed NCT01466387 Phase 3
9 Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) Completed NCT01345240 Phase 3
10 The Yellow Fever Vaccine Immunity in HIV Infected Patients : Development of New Assays for Virological and Immunological Monitoring in HIV Infected Patient. Active, not recruiting NCT01426243 Phase 3
11 Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. Active, not recruiting NCT02699099 Phase 3
12 Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) Administered With a Yellow Fever Vaccine in Adults Not yet recruiting NCT03342898 Phase 3
13 Study of Live Attenuated Japanese Encephalitis Vaccine (ChimeriVax™-JE) and Yellow Fever Vaccine (STAMARIL®) Completed NCT00982137 Phase 2
14 Immune Response to Different Schedules of a Tetravalent Dengue Vaccine Given With or Without Yellow Fever Vaccine Completed NCT01488890 Phase 2
15 The Role of Pre-existing Cross-reactive Antibodies in Determining the Efficacy of Vaccination in Humans Completed NCT01943305 Phase 2
16 Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis Completed NCT00723489 Phase 1, Phase 2 YFV-17D Placebo
17 Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen Completed NCT00436007 Phase 2
18 Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Peruvian Children Aged 2 to 11 Years Completed NCT00788151 Phase 2
19 Study of ChimeriVax™ Dengue Tetravalent Vaccine in Adult Subjects Completed NCT00730288 Phase 2
20 Impact of GSK Biologicals' 2189242A Vaccine on Nasopharyngeal Carriage, Safety & Immunogenicity in Children & Infants Completed NCT01262872 Phase 2
21 Yellow Fever Vaccine on Statin/ Non Statin Subjects Recruiting NCT03116802 Phase 2 Stamaril (live attenuated yellow fever vaccine)
22 Trial of Yellow Fever Inactivated Vaccine Completed NCT00995865 Phase 1
23 Yellow Fever Virus Vaccine and Immune Globulin Study Completed NCT00254826 Phase 1
24 Phase I Study of West Nile Virus Vaccine Completed NCT00300417 Phase 1 VRC-WNVDNA020-00-VP
25 A Phase I Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of MVA-BN Yellow Fever Vaccine With and Without Montanide ISA-720 Adjuvant in 18-45 Year Old Healthy Volunteers Active, not recruiting NCT02743455 Phase 1 ISA-720
26 A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects. Active, not recruiting NCT02963909 Phase 1
27 Yellow Fever Vaccination Under Low Dose Methotrexate Therapy Unknown status NCT02383680
28 Immunity After Two Doses of Yellow Fever Vaccine Completed NCT02572518
29 Characterization of T Cell Responses Following Yellow Fever Virus Vaccination in Healthy Adults Completed NCT00616356
30 Clinical Study of Immunity Duration of Yellow Fever Vaccine in Military Completed NCT03338231
31 Training Study to Characterize Biomarkers to Chickenpox and Yellow Fever Vaccines Completed NCT01765413
32 The Effect of Extended Yellow Fever Vaccine Information on Symptom Reports Following Vaccination Completed NCT00708630
33 Seroprevalence and Incidence of Lassa Fever in the Rural Commune of Sibirila, District of Bougouni, Mali Completed NCT02311387
34 Evaluation of the Safety & Performance of 2 Intradermal Safety Devices Completed NCT02556047
35 Study to Evaluate the Incidence, Clinical Characteristics and Economic Burden of Dengue in Brazilian Children Completed NCT01391819
36 The Interaction Between Measles and DTP Vaccination Completed NCT02710045
37 Turnover of Antigen Specific Lymphocytes After Immunization With the Yellow Fever Vaccine Recruiting NCT01290055
38 Human Immune Responses to The Yellow Fever Virus Vaccine Recruiting NCT00694655
39 Immune Responses to Yellow Fever Vaccine Recruiting NCT01244802
40 Cohort of Patients Infected by an Arbovirus Recruiting NCT01099852
41 Vaccines Immunogenicity in Renal, Hepatic, Cardiac or Pulmonary Transplanted Children Recruiting NCT03180359
42 Complementary Study of the Duration of Post-vaccination Against Yellow Fever Immunity in Children Active, not recruiting NCT02990182
43 Yellow Fever Vaccine in Patients With Rheumatic Diseases Not yet recruiting NCT03430388

Search NIH Clinical Center for Yellow Fever

Cochrane evidence based reviews: yellow fever

Genetic Tests for Yellow Fever

Anatomical Context for Yellow Fever

MalaCards organs/tissues related to Yellow Fever:

38
Liver, Skin, T Cells, Kidney, Eye, Heart, Nk Cells

Publications for Yellow Fever

Articles related to Yellow Fever:

(show top 50) (show all 700)
# Title Authors Year
1
Modelling the large-scale yellow fever outbreak in Luanda, Angola, and the impact of vaccination. ( 29338001 )
2018
2
Immunogenicity of Fractional-Dose Vaccine during a Yellow Fever Outbreak - Preliminary Report. ( 29443626 )
2018
3
Metagenomic analysis reveals Hepatitis A virus in suspected yellow fever cases in Brazil. ( 29211109 )
2018
4
Existing and potential infection risk zones of yellow fever worldwide: a modelling analysis. ( 29398634 )
2018
5
Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204. ( 29387474 )
2018
6
Yellow Fever Vaccine for People Living With HIV Infection. ( 29217414 )
2018
7
Plant-Produced Subunit Vaccine Candidates against Yellow Fever Induce Virus Neutralizing Antibodies and Confer Protection against Viral Challenge in Animal Models. ( 29231157 )
2018
8
Evidence for Multiple Sylvatic Transmission Cycles During the 2016-2017 Yellow Fever Virus Outbreak, Brazil. ( 29427798 )
2018
9
Zika, dengue and yellow fever viruses induce differential anti-viral immune responses in human monocytic and first trimester trophoblast cells. ( 29331320 )
2018
10
Yellow fever vaccination coverage in French Guiana. ( 29303736 )
2018
11
Re-evaluate yellow fever risk in Asia-Pacific region. ( 29388975 )
2018
12
A natural agonist of mosquito TRPA1 from the medicinal plant Cinnamosma fragrans that is toxic, antifeedant, and repellent to the yellow fever mosquito Aedes aegypti. ( 29425195 )
2018
13
Notes from the Field: Errors in Administration of an Excess Dosage of Yellow Fever Vaccine - United States, 2017. ( 29370153 )
2018
14
Yellow fever: a major threat to public health. ( 29407015 )
2018
15
Synthesis and structure-activity relationships of carbohydrazides and 1,3,4-oxadiazole derivatives bearing imidazolidine moiety against the yellow fever and dengue vector, Aedes aegypti. ( 28869331 )
2017
16
Autochthonous Japanese Encephalitis with Yellow Fever Coinfection in Africa. ( 28402771 )
2017
17
Development of a recombinant yellow fever vector expressing a HIV clade C founder envelope gp120. ( 28837840 )
2017
18
Assessment of risk of dengue and yellow fever virus transmission in three major Kenyan cities based on Stegomyia indices. ( 28817563 )
2017
19
Phylodynamics of Yellow Fever Virus in the Americas: new insights into the origin of the 2017 Brazilian outbreak. ( 28785067 )
2017
20
Urine as sample for molecular diagnosis of natural yellow fever virus infections. ( 28855304 )
2017
21
Prevalence and titers of yellow fever virus neutralizing antibodies in previously vaccinated adults. ( 28380113 )
2017
22
Oviposition behavior of Haemagogus leucocelaenus (Diptera: culicidae), a vector of wild yellow fever in Brazil. ( 28793027 )
2017
23
Importation of yellow fever into China: assessing travel patterns. ( 28426111 )
2017
24
Thiosemicarbazones and Phthalyl-Thiazoles compounds exert antiviral activity against yellow fever virus and Saint Louis encephalitis virus. ( 28068627 )
2017
25
Geographic patterns and environmental factors associated with human yellow fever presence in the Americas. ( 28886023 )
2017
26
Not a polar island: yellow fever, Spanish medical research, and the struggle for scientific and political hegemony in late nineteenth century Cuba. ( 29412261 )
2017
27
Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination. ( 28386132 )
2017
28
Addressing a Yellow Fever Vaccine Shortage - United States, 2016-2017. ( 28472025 )
2017
29
Dengue and yellow fever virus vectors: seasonal abundance, diversity and resting preferences in three Kenyan cities. ( 29284522 )
2017
30
Yellow Fever in an Unvaccinated Traveler to Peru. ( 29308400 )
2017
31
Global yellow fever vaccination coverage from 1970 to 2016: an adjusted retrospective analysis. ( 28822780 )
2017
32
Lineage-Specific Real-Time RT-PCR for Yellow Fever Virus Outbreak Surveillance, Brazil. ( 28949285 )
2017
33
Max Theiler (1899-1972): Creator of the yellow fever vaccine. ( 28429035 )
2017
34
Resurgence of yellow fever in Brazil: Overview and possible control options. ( 28889757 )
2017
35
Eliminate Yellow fever Epidemics (EYE): a global strategy, 2017a892026. ( 28429585 )
2017
36
Protein structure shapes immunodominance in the CD4 T cell response to yellow fever vaccination. ( 28827760 )
2017
37
T Cell-Mediated Immunity towards Yellow Fever Virus and Useful Animal Models. ( 28398253 )
2017
38
Yellow fever live attenuated vaccine: A very successful live attenuated vaccine but still we have problems controlling the disease. ( 28366605 )
2017
39
An Atypical Local Vesicular Reaction to the Yellow Fever Vaccine. ( 28925936 )
2017
40
Heparin removal by ecteola-cellulose pre-treatment enables the use of plasma samples for accurate measurement of anti-Yellow fever virus neutralizing antibodies. ( 28514646 )
2017
41
Yellow Fever Outbreak - Kongo Central Province, Democratic Republic of the Congo, August 2016. ( 28358796 )
2017
42
Identification and initial characterization of matrix metalloproteinases in the yellow fever mosquito, Aedes aegypti. ( 28054419 )
2017
43
Yellow fever vaccination: estimating coverage. ( 28822782 )
2017
44
Reemergence of yellow fever in Ethiopia after 50A years, 2013: epidemiological and entomological investigations. ( 28506254 )
2017
45
Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus. ( 29285718 )
2017
46
Notes from the Field: Adverse Events Following a Mass Yellow Fever Immunization Campaign - Kongo Central Province, Democratic Republic of the Congo, September 2016. ( 28358792 )
2017
47
Efficacy of Some Wearable Devices Compared with Spray-On Insect Repellents for the Yellow Fever Mosquito, Aedes aegypti (L.) (Diptera: Culicidae). ( 28423421 )
2017
48
The Yellow Fever Vaccine Misadventure of 1942. ( 28492447 )
2017
49
Yellow fever in Africa and the Americas, 2016. ( 28799735 )
2017
50
Notes from the Field: Fatal Yellow Fever in a Traveler Returning From Peru - New York, 2016. ( 28859053 )
2017

Variations for Yellow Fever

Expression for Yellow Fever

Search GEO for disease gene expression data for Yellow Fever.

Pathways for Yellow Fever

Pathways related to Yellow Fever according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.77 CCL5 CCR5 IFNB1 IL17A IL1RN IL5
2
Show member pathways
13.21 CCL5 CCR5 IL17A IL5 STAT1 TLR9
3
Show member pathways
13.07 CCL5 CCR5 IFNB1 IL17A IL1RN IL5
4
Show member pathways
12.74 CCL5 IFNB1 IL1RN IRF7 OAS1 STAT1
5
Show member pathways
12.45 CCL5 EIF2AK4 IFNB1 IRF7 OAS1 RSAD2
6
Show member pathways
12.38 CCR5 IFNB1 IRF7 STAT1
7
Show member pathways
12.37 IFNB1 IRF7 OAS1 RSAD2 STAT1
8
Show member pathways
12.34 CCL5 IFNB1 IRF7 STAT1 TLR9
9
Show member pathways
12.17 IFNB1 IL5 STAT1
10 12.07 CCL5 IL17A IL1RN IRF7 OAS1 RSAD2
11 12.04 IFNB1 STAT1 TLR9
12
Show member pathways
11.99 IFNB1 STAT1 TLR9
13
Show member pathways
11.84 IL5 STAT1 TLR9
14 11.84 EIF2AK4 IFNB1 IRF7 OAS1 STAT1
15
Show member pathways
11.74 IL17A STAT1 TLR9
16
Show member pathways
11.67 IL17A STAT1 TLR9
17 11.66 CCR5 IFNB1 STAT1
18 11.59 IFNB1 IL5 IRF7
19 11.38 CCL5 CCR5 IL1RN
20
Show member pathways
11.38 IFNB1 IL17A IL5 IRF7 OAS1 RSAD2
21 11.24 IFNB1 OAS1 STAT1
22 11.08 IFNB1 IL5
23 10.97 CCL5 IFNB1
24
Show member pathways
10.94 IRF7 OAS1 STAT1

GO Terms for Yellow Fever

Cellular components related to Yellow Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.23 CCL5 F10 IFNB1 IL17A IL1RN IL5

Biological processes related to Yellow Fever according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.88 EIF2AK4 IRF7 OAS1 RSAD2 TLR9
2 immune response GO:0006955 9.88 CCL5 CCR5 IL17A IL1RN IL5 OAS1
3 regulation of receptor activity GO:0010469 9.85 CCL5 IFNB1 IL17A IL1RN IL5
4 inflammatory response GO:0006954 9.85 CCL5 CCR5 IL17A IL1RN IL5 TLR9
5 viral process GO:0016032 9.83 CCR5 EIF2AK4 IRF7 RSAD2 STAT1
6 interferon-gamma-mediated signaling pathway GO:0060333 9.67 IRF7 OAS1 STAT1
7 negative regulation of viral genome replication GO:0045071 9.62 CCL5 IFNB1 OAS1 RSAD2
8 regulation of type I interferon-mediated signaling pathway GO:0060338 9.6 IFNB1 STAT1
9 positive regulation of defense response to virus by host GO:0002230 9.59 EIF2AK4 STAT1
10 positive regulation of interferon-beta production GO:0032728 9.58 IRF7 TLR9
11 positive regulation of innate immune response GO:0045089 9.58 CCL5 IFNB1
12 T cell activation involved in immune response GO:0002286 9.57 EIF2AK4 IFNB1
13 positive regulation of JAK-STAT cascade GO:0046427 9.56 CCL5 IL5
14 dendritic cell chemotaxis GO:0002407 9.55 CCL5 CCR5
15 response to virus GO:0009615 9.55 CCL5 IFNB1 IRF7 OAS1 RSAD2
16 cellular response to interferon-beta GO:0035458 9.54 IFNB1 STAT1
17 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.52 STAT1 TLR9
18 positive regulation of interferon-alpha production GO:0032727 9.51 IRF7 STAT1
19 negative regulation of macrophage apoptotic process GO:2000110 9.43 CCL5 CCR5 IRF7
20 defense response to virus GO:0051607 9.43 EIF2AK4 IFNB1 IRF7 OAS1 RSAD2 STAT1
21 type I interferon signaling pathway GO:0060337 9.02 IFNB1 IRF7 OAS1 RSAD2 STAT1

Molecular functions related to Yellow Fever according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphatidylinositol phospholipase C activity GO:0004435 9.26 CCL5 CCR5
2 interleukin-1 receptor binding GO:0005149 9.16 IL1RN TLR9
3 cytokine activity GO:0005125 9.02 CCL5 IFNB1 IL17A IL1RN IL5
4 CCR5 chemokine receptor binding GO:0031730 8.96 CCL5 STAT1

Sources for Yellow Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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