YF
MCID: YLL002
MIFTS: 58

Yellow Fever (YF) malady

Categories: Rare diseases, Infectious diseases, Skin diseases

Aliases & Classifications for Yellow Fever

Aliases & Descriptions for Yellow Fever:

Name: Yellow Fever 12 50 56 52 3 42 14 69
Jungle Yellow Fever 12 69
Urban Yellow Fever 12 69
Yf 50 56
Sylvatic Yellow Fever 12
Yellow Fever, Sylvan 12
Bronze John 56
Yellow Jack 56

Characteristics:

Orphanet epidemiological data:

56
yellow fever
Prevalence: <1/1000000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 56  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:9682
ICD9CM 35 060 060.9
MeSH 42 D015004
NCIt 47 C35547
Orphanet 56 ORPHA99829
UMLS via Orphanet 70 C0043395
MESH via Orphanet 43 D015004
ICD10 via Orphanet 34 A95.0 A95.1 A95.9
UMLS 69 C0043395

Summaries for Yellow Fever

Disease Ontology : 12 A viral infectious disease that results_in infection, has material basis in Yellow fever virus, which is transmitted_by Aedes, transmitted_by Haemagogus, or transmitted_by Sabethes species of mosquitoes. The infection has symptom fever, has symptom muscle pain, has symptom backache, has symptom headache, has symptom shivers, has symptom loss of appetite, has symptom jaundice, and has symptom bleeding from the mouth, nose, eyes or stomach leading to vomitus containing blood.

MalaCards based summary : Yellow Fever, also known as jungle yellow fever, is related to hemorrhagic fever and kyasanur forest disease, and has symptoms including fever, muscle pain and backache. An important gene associated with Yellow Fever is EIF2AK4 (Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Vaccines and Vitamin A have been mentioned in the context of this disorder. Affiliated tissues include liver, skin and eye, and related phenotypes are hematopoietic system and homeostasis/metabolism

CDC : 3 Yellow fever virus is found in tropical and subtropical areas in South America and Africa. The virus is transmitted to people by the bite of an infected mosquito. Yellow fever is a very rare cause of illness in U.S. travelers. Illness ranges in severity from a self-limited febrile illness to severe liver disease with bleeding. 

Wikipedia : 71 Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever,... more...

Related Diseases for Yellow Fever

Diseases related to Yellow Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 104)
id Related Disease Score Top Affiliating Genes
1 hemorrhagic fever 11.0
2 kyasanur forest disease 10.7
3 eating seizures 10.2 CCL5 CCR5
4 encephalitis 10.2
5 hypercementosis 10.2 CCL5 IL5
6 hepatitis c virus 10.1 CCR5 OAS1 RSAD2
7 marasmus 10.1 IL4 IL5
8 osteodysplasty precocious of danks mayne and kozlowski 10.1 CCL5 CCR5 IL4
9 cerebral primitive neuroectodermal tumor 10.1 CCL5 IL4 IL5
10 papillary squamous carcinoma 10.1 IL4 IL5
11 retinal ischemia 10.1 CCL2 CCL5 CCR5
12 apricot allergy 10.1 CCL5 IL4 IL5
13 trachea leiomyoma 10.1 CCL5 IL4 IL5
14 visceral steatosis 10.1 CCL5 IL4 IL5
15 cutaneous fibrous histiocytoma 10.1 CCL5 IL4 IL5
16 smooth muscle tumor 10.1 CCL2 CCL5 IL5
17 bone peripheral neuroepithelioma 10.1 IL4 IL5 SCP2
18 ethmoid sinusitis 10.1 CCL5 IL4 IL5
19 indian plum allergy 10.1 IL4 IL5 SCP2
20 inflamed seborrheic keratosis 10.1 CCL5 IL4 IL5
21 lens-induced iridocyclitis 10.1 IL4 IL5
22 patellar tendinitis 10.1 CCL5 IL4 IL5
23 pulmonary tuberculosis 10.1 CCL5 IL4 IL5
24 spastic paraplegia 3a, autosomal dominant 10.0 IL4 IL5
25 spontaneous ocular nystagmus 10.0 CCL5 IL4 IL5
26 paratyphoid fever 10.0 IL4 IL5 SCP2
27 lipid storage disease 10.0 CCL5 IL4 IL5
28 thelaziasis 10.0 IL4 IL5
29 lymphoblastic leukemia 10.0 IL4 IL5
30 malignant peritoneal solitary fibrous tumor 10.0 CCL5 IL4 IL5
31 membranoproliferative glomerulonephritis 10.0 CCR5 IL4 IL5
32 plantar fasciitis 10.0 CCL2 CCL5 CCR5 RSAD2
33 rectum squamous cell carcinoma 10.0 CCL2 CCL5 IL5
34 measles 10.0
35 st. louis encephalitis 10.0
36 hepatitis 10.0
37 status epilepticus 10.0 CCL2 CCL5 IL4
38 proximal symphalangism 10.0 CCL2 CCR5 IL4
39 urethral intrinsic sphincter deficiency 10.0 CCL2 IL4 IL5
40 hypersensitivity vasculitis 10.0 IL4 IL5
41 neonatal jaundice 10.0 CCL2 CCL5 IL4
42 pigmentation disease 10.0 CCL2 CCL5 IL4
43 mediastinum neurofibroma 10.0 CCL5 IL4 IL5 SCP2
44 nervous system cancer 10.0 CCL2 CCL5 IL4
45 malaria 10.0
46 hyperimmunoglobulin syndrome 10.0 CCL2 CCL5 STAT1
47 chikungunya 9.9
48 smallpox 9.9
49 japanese encephalitis 9.9
50 egg allergy 9.9

Graphical network of the top 20 diseases related to Yellow Fever:



Diseases related to Yellow Fever

Symptoms & Phenotypes for Yellow Fever

Symptoms:

12
  • fever
  • muscle pain
  • backache
  • headache
  • shivers
  • loss of appetite
  • jaundice
  • bleeding from the mouth

Human phenotypes related to Yellow Fever:

56 32 (show all 29)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 arthralgia 56 32 Frequent (79-30%) HP:0002829
2 myalgia 56 32 Frequent (79-30%) HP:0003326
3 fever 56 32 Very frequent (99-80%) HP:0001945
4 headache 56 32 Very frequent (99-80%) HP:0002315
5 photophobia 56 32 Occasional (29-5%) HP:0000613
6 chest pain 56 32 Frequent (79-30%) HP:0100749
7 abdominal pain 56 32 Frequent (79-30%) HP:0002027
8 diarrhea 56 32 Frequent (79-30%) HP:0002014
9 nausea and vomiting 56 32 Frequent (79-30%) HP:0002017
10 lethargy 56 32 Occasional (29-5%) HP:0001254
11 menometrorrhagia 56 32 Frequent (79-30%) HP:0400008
12 hypothermia 56 32 Occasional (29-5%) HP:0002045
13 encephalitis 56 32 Occasional (29-5%) HP:0002383
14 hypotension 56 32 Occasional (29-5%) HP:0002615
15 renal insufficiency 56 32 Occasional (29-5%) HP:0000083
16 proteinuria 56 32 Frequent (79-30%) HP:0000093
17 nephropathy 56 32 Occasional (29-5%) HP:0000112
18 dehydration 56 32 Occasional (29-5%) HP:0001944
19 arrhythmia 56 32 Occasional (29-5%) HP:0011675
20 congestive heart failure 56 32 Occasional (29-5%) HP:0001635
21 jaundice 56 32 Frequent (79-30%) HP:0000952
22 anorexia 56 32 Frequent (79-30%) HP:0002039
23 gastrointestinal hemorrhage 56 32 Frequent (79-30%) HP:0002239
24 meningitis 56 32 Occasional (29-5%) HP:0001287
25 acute hepatic failure 56 32 Occasional (29-5%) HP:0006554
26 malignant hyperthermia 56 32 Occasional (29-5%) HP:0002047
27 oliguria 56 32 Frequent (79-30%) HP:0100520
28 spontaneous abortion 56 32 Frequent (79-30%) HP:0005268
29 cardiorespiratory arrest 56 32 Occasional (29-5%) HP:0006543

MGI Mouse Phenotypes related to Yellow Fever:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.96 CCL5 CCR5 EIF2AK4 FGA IL1RL1 IL4
2 homeostasis/metabolism MP:0005376 9.85 F10 FGA IL4 IL5 IRF7 RSAD2
3 immune system MP:0005387 9.73 CCR5 EIF2AK4 FGA IL1RL1 IL4 IL5
4 liver/biliary system MP:0005370 9.17 CCR5 EIF2AK4 FGA IL4 IL5 SCP2

Drugs & Therapeutics for Yellow Fever

Drugs for Yellow Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 64)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
2
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 11103-57-4, 68-26-8 445354
3
Lactitol Phase 3 585-86-4 3871
4 Heptavalent Pneumococcal Conjugate Vaccine Phase 3,Phase 2
5 Vitamins Phase 3
6 Trace Elements Phase 3
7 Protective Agents Phase 3
8 Retinol palmitate Phase 3
9 Micronutrients Phase 3
10 Antioxidants Phase 3
11 Pharmaceutical Solutions Phase 3
12 Krestin Phase 3
13 retinol Nutraceutical Phase 3
14
Benzocaine Approved Phase 1, Phase 2 1994-09-7, 94-09-7 2337
15 tannic acid Approved, Nutraceutical Phase 1, Phase 2
16 Immunoglobulins Phase 2,Phase 1
17 Antimetabolites Phase 2
18 Antibodies Phase 2,Phase 1
19 Antiviral Agents Phase 2
20 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
21 Hypolipidemic Agents Phase 2
22 Anticholesteremic Agents Phase 2
23 Anti-Inflammatory Agents Phase 2,Phase 1
24 Lipid Regulating Agents Phase 2
25
Dexamethasone Approved, Investigational, Vet_approved Phase 1 50-02-2 5743
26
Mannitol Approved, Investigational Phase 1 69-65-8 453 6251
27
Lenograstim Approved Phase 1 135968-09-1
28
Aluminum hydroxide Approved Phase 1 21645-51-2
29 Aluminum sulfate Phase 1
30 gamma-Globulins Phase 1
31 Immunoglobulins, Intravenous Phase 1
32 Rho(D) Immune Globulin Phase 1
33 Dexamethasone acetate Phase 1 1177-87-3
34 diuretics Phase 1
35 glucocorticoids Phase 1
36
protease inhibitors Phase 1
37 Adjuvants, Immunologic Phase 1
38 Natriuretic Agents Phase 1
39 Gastrointestinal Agents Phase 1
40 HIV Protease Inhibitors Phase 1
41 Hormone Antagonists Phase 1
42 Dexamethasone 21-phosphate Phase 1
43 Hormones Phase 1
44 Peripheral Nervous System Agents Phase 1
45 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 1
46 Antiemetics Phase 1
47 BB 1101 Phase 1
48 Autonomic Agents Phase 1
49 Antineoplastic Agents, Hormonal Phase 1
50
Methotrexate Approved 1959-05-2, 59-05-2 126941

Interventional clinical trials:

(show all 45)
id Name Status NCT ID Phase
1 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4
2 Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali Completed NCT02286895 Phase 4
3 Immunity Period After One Dose of Yellow Fever Vaccine in Adults and Children (Paraiba Study) Recruiting NCT02555072 Phase 4
4 Immunogenicity and Safety of Fractional Doses of Yellow Fever Vaccines (YEFE) Not yet recruiting NCT02991495 Phase 4
5 Immunogenicity and Safety of the Yellow Fever Vaccine in HIV Infected Individuals Not yet recruiting NCT03132311 Phase 4
6 Study of Yellow Fever Vaccine Administered With Tetravalent Dengue Vaccine in Healthy Toddlers Completed NCT01436396 Phase 3
7 A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults Completed NCT01466387 Phase 3
8 Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) Completed NCT01345240 Phase 3
9 Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine. Recruiting NCT02699099 Phase 3
10 The Yellow Fever Vaccine Immunity in HIV Infected Patients : Development of New Assays for Virological and Immunological Monitoring in HIV Infected Patient. Active, not recruiting NCT01426243 Phase 3
11 Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency Not yet recruiting NCT03113760 Phase 3
12 Study of Live Attenuated Japanese Encephalitis Vaccine (ChimeriVax™-JE) and Yellow Fever Vaccine (STAMARIL®) Completed NCT00982137 Phase 2
13 Immune Response to Different Schedules of a Tetravalent Dengue Vaccine Given With or Without Yellow Fever Vaccine Completed NCT01488890 Phase 2
14 The Role of Pre-existing Cross-reactive Antibodies in Determining the Efficacy of Vaccination in Humans Completed NCT01943305 Phase 2
15 Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis Completed NCT00723489 Phase 1, Phase 2
16 Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen Completed NCT00436007 Phase 2
17 Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Peruvian Children Aged 2 to 11 Years Completed NCT00788151 Phase 2
18 Study of ChimeriVax™ Dengue Tetravalent Vaccine in Adult Subjects Completed NCT00730288 Phase 2
19 Impact of GSK Biologicals' 2189242A Vaccine on Nasopharyngeal Carriage, Safety & Immunogenicity in Children & Infants Completed NCT01262872 Phase 2
20 Efficacy of Favipiravir Against Ebola (JIKI) Completed NCT02329054 Phase 2
21 Yellow Fever Vaccine on Statin/ Non Statin Subjects Recruiting NCT03116802 Phase 2
22 Tolerance and Activity Evaluation of High Doses of Favipiravir Against Ebola Virus in the Semen Recruiting NCT02739477 Phase 2
23 Trial of Yellow Fever Inactivated Vaccine Completed NCT00995865 Phase 1
24 Yellow Fever Virus Vaccine and Immune Globulin Study Completed NCT00254826 Phase 1
25 Phase I Study of West Nile Virus Vaccine Completed NCT00300417 Phase 1
26 A Phase I Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of MVA-BN Yellow Fever Vaccine With and Without Montanide ISA-720 Adjuvant in 18-45 Year Old Healthy Volunteers Recruiting NCT02743455 Phase 1
27 A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects. Recruiting NCT02963909 Phase 1
28 Improving White Blood Cell Collection From Healthy Donors Recruiting NCT01553214 Phase 1
29 Yellow Fever Vaccination Under Low Dose Methotrexate Therapy Unknown status NCT02383680
30 Immunity After Two Doses of Yellow Fever Vaccine Completed NCT02572518
31 Characterization of T Cell Responses Following Yellow Fever Virus Vaccination in Healthy Adults Completed NCT00616356
32 Training Study to Characterize Biomarkers to Chickenpox and Yellow Fever Vaccines Completed NCT01765413
33 The Effect of Extended Yellow Fever Vaccine Information on Symptom Reports Following Vaccination Completed NCT00708630
34 Seroprevalence and Incidence of Lassa Fever in the Rural Commune of Sibirila, District of Bougouni, Mali Completed NCT02311387
35 Evaluation of the Safety & Performance of 2 Intradermal Safety Devices Completed NCT02556047
36 Study to Evaluate the Incidence, Clinical Characteristics and Economic Burden of Dengue in Brazilian Children Completed NCT01391819
37 The Interaction Between Measles and DTP Vaccination Completed NCT02710045
38 A Trial Comparing the Uncovered to the Covered Wallstent in the Palliation of Malignant Bile Duct Strictures Completed NCT01047332
39 A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease Completed NCT01182532
40 Turnover of Antigen Specific Lymphocytes After Immunization With the Yellow Fever Vaccine Recruiting NCT01290055
41 Human Immune Responses to The Yellow Fever Virus Vaccine Recruiting NCT00694655
42 Immune Responses to Yellow Fever Vaccine Recruiting NCT01244802
43 Cohort of Patients Infected by an Arbovirus Recruiting NCT01099852
44 Vaccines Immunogenicity in Renal, Hepatic, Cardiac or Pulmonary Transplanted Children Recruiting NCT03180359
45 Complementary Study of the Duration of Post-vaccination Against Yellow Fever Immunity in Children Active, not recruiting NCT02990182

Search NIH Clinical Center for Yellow Fever

Cochrane evidence based reviews: yellow fever

Genetic Tests for Yellow Fever

Anatomical Context for Yellow Fever

MalaCards organs/tissues related to Yellow Fever:

39
Liver, Skin, Eye, Kidney, T Cells, Heart, Nk Cells

Publications for Yellow Fever

Articles related to Yellow Fever:

(show top 50) (show all 660)
id Title Authors Year
1
Reemergence of yellow fever in Ethiopia after 50A years, 2013: epidemiological and entomological investigations. ( 28506254 )
2017
2
Importation of yellow fever into China: assessing travel patterns. ( 28426111 )
2017
3
Identification and initial characterization of matrix metalloproteinases in the yellow fever mosquito, Aedes aegypti. ( 28054419 )
2017
4
Yellow Fever Virus Modulates the Expression of Key Proteins Related to the microRNA Pathway in the Human Hepatocarcinoma Cell Line HepG2. ( 28388330 )
2017
5
Adaptive Diversification between Yellow Fever Virus West African and South American Lineages: A Genome-Wide Study. ( 28044043 )
2017
6
Autochthonous Japanese Encephalitis with Yellow Fever Coinfection in Africa. ( 28402771 )
2017
7
Yellow fever from Angola and Congo: a storm gathers. ( 28424031 )
2017
8
Max Theiler (1899-1972): Creator of the yellow fever vaccine. ( 28429035 )
2017
9
Addressing a Yellow Fever Vaccine Shortage - United States, 2016-2017. ( 28472025 )
2017
10
Heparin removal by ecteola-cellulose pre-treatment enables the use of plasma samples for accurate measurement of anti-Yellow fever virus neutralizing antibodies. ( 28514646 )
2017
11
The Yellow Fever Vaccine Misadventure of 1942. ( 28492447 )
2017
12
T Cell-Mediated Immunity towards Yellow Fever Virus and Useful Animal Models. ( 28398253 )
2017
13
Efficacy of Some Wearable Devices Compared with Spray-On Insect Repellents for the Yellow Fever Mosquito, Aedes aegypti (L.) (Diptera: Culicidae). ( 28423421 )
2017
14
What to expect from the 2017 yellow fever outbreak in Brazil? ( 28423092 )
2017
15
Yellow fever in the Americas: the growing concern about new epidemics. ( 28529708 )
2017
16
Yellow Fever Outbreak - Kongo Central Province, Democratic Republic of the Congo, August 2016. ( 28358796 )
2017
17
Yellow fever live attenuated vaccine: A very successful live attenuated vaccine but still we have problems controlling the disease. ( 28366605 )
2017
18
Eliminate Yellow fever Epidemics (EYE): a global strategy, 2017a892026. ( 28429585 )
2017
19
Prevalence and titers of yellow fever virus neutralizing antibodies in previously vaccinated adults. ( 28380113 )
2017
20
Adaptive immune responses to booster vaccination against yellow fever virus are much reduced compared to those after primary vaccination. ( 28386132 )
2017
21
Notes from the Field: Adverse Events Following a Mass Yellow Fever Immunization Campaign - Kongo Central Province, Democratic Republic of the Congo, September 2016. ( 28358792 )
2017
22
Thiosemicarbazones and Phthalyl-Thiazoles compounds exert antiviral activity against yellow fever virus and Saint Louis encephalitis virus. ( 28068627 )
2017
23
Narcolepsy Following Yellow Fever Vaccination: A Case Report. ( 27559330 )
2016
24
Reining in Angola's yellow fever outbreak. ( 27843160 )
2016
25
Safety of yellow fever vaccine in Indian travellers: A prospective observational study. ( 28361832 )
2016
26
Yellow fever virus capsid protein is a potent suppressor of RNA silencing that binds double-stranded RNA. ( 27849599 )
2016
27
Yellow fever vaccine supply: a possible solution. ( 27116054 )
2016
28
Yellow fever: a global reckoning. ( 27115797 )
2016
29
Is Sri Lanka prepared for yellow fever outbreaks? A case study. ( 27855869 )
2016
30
INFECTIOUS DISEASES. Yellow fever outbreak triggers vaccine alarm. ( 27124428 )
2016
31
Frequency of histopathological changes in Howler monkeys ( Alouatta sp.) naturally infected with yellow fever virus in Brazil. ( 27163561 )
2016
32
Fractional dosing of yellow fever vaccine to extend supply: a modelling study. ( 27837923 )
2016
33
Animal models of yellow fever and their application in clinical research. ( 27093699 )
2016
34
Comparative study of adverse events after yellow fever vaccination between elderly and non-elderly travellers: questionnaire survey in Japan over a 1-year period. ( 27021495 )
2016
35
Yellow fever outbreaks in SALo Paulo State, Brazil, 2000-2010. ( 27869924 )
2016
36
Yellow fever vaccination during treatment with infliximab in a patient with ulcerative colitis: A case report. ( 27612222 )
2016
37
Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication. ( 26739057 )
2016
38
Yellow fever vaccine: worthy friend or stealthy foe? ( 27087465 )
2016
39
Why is the yellow fever outbreak in Angola a 'threat to the entire world'? ( 27163382 )
2016
40
International Health Regulations in practice: Focus on yellow fever and poliomyelitis. ( 27541082 )
2016
41
Vigilance still needed to contain Africa's yellow fever outbreak, says WHO. ( 27586155 )
2016
42
Yellow fever in Africa: a disaster waiting to happen. ( 27477983 )
2016
43
Contrasting female-male mortality ratios after routine vaccinations with pentavalent vaccine versus measles and yellow fever vaccine. A cohort study from urban Guinea-Bissau. ( 27475473 )
2016
44
Modelling a way out of yellow fever. ( 27837922 )
2016
45
A Novel Benzodiazepine Compound Inhibits Yellow Fever Virus Infection by Specifically Targeting NS4B Protein. ( 27654301 )
2016
46
First case of yellow fever vaccine-associated viscerotropic disease (YEL-AVD) in Hong Kong. ( 27087559 )
2016
47
Another pandemic disaster looms: yellow fever spreading from Angola. ( 27642446 )
2016
48
Inadvertent yellow fever vaccination of a patient with Crohn's disease treated with infliximab and methotrexate. ( 27571912 )
2016
49
The 17D-204 Vaccine Strain-Induced Protection against Virulent Yellow Fever Virus Is Mediated by Humoral Immunity and CD4+ but not CD8+ T Cells. ( 27463517 )
2016
50
A Meta-Analysis of Serological Response Associated with Yellow Fever Vaccination. ( 27928091 )
2016

Variations for Yellow Fever

Expression for Yellow Fever

Search GEO for disease gene expression data for Yellow Fever.

Pathways for Yellow Fever

Pathways related to Yellow Fever according to GeneCards Suite gene sharing:

(show all 22)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.77 CCL2 CCL5 CCR5 FGA IL1RL1 IL4
2
Show member pathways
13.22 CCL2 CCL5 CCR5 IL4 IL5 STAT1
3
Show member pathways
12.79 CCL2 CCL5 IL1RL1 IRF7 OAS1 STAT1
4
Show member pathways
12.47 CCL2 CCL5 CCR5 FGA IL1RL1 IL4
5
Show member pathways
12.45 CCL2 CCL5 EIF2AK4 IL4 IRF7 OAS1
6
Show member pathways
12.34 IRF7 OAS1 RSAD2 STAT1
7 12.3 CCL2 CCL5 IL4 IRF7 OAS1 RSAD2
8 11.88 EIF2AK4 IRF7 OAS1 STAT1
9
Show member pathways
11.85 CCL2 CCL5 CCR5
10 11.81 CCL2 IL4 STAT1
11
Show member pathways
11.8 CCR5 IL4 STAT1
12
Show member pathways
11.64 IL4 IL5 IRF7 OAS1 RSAD2 STAT1
13 11.63 IL4 IL5 STAT1
14 11.6 IL1RL1 IL4 IL5
15 11.47 CCL2 CCL5 IL4 IL5
16 11.34 IL1RL1 IL4 IL5
17 11.31 CCL2 CCL5 CCR5 IL4
18 11.04 CCL2 CCL5 IL4 IL5
19 11.02 IL4 IL5
20
Show member pathways
10.94 IRF7 OAS1 STAT1
21 10.87 CCL2 STAT1
22 10.73 IL4 IL5

GO Terms for Yellow Fever

Cellular components related to Yellow Fever according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CCL2 CCL5 F10 FGA IL1RL1 IL4
2 external side of plasma membrane GO:0009897 8.92 CCR5 FGA IL1RL1 IL4

Biological processes related to Yellow Fever according to GeneCards Suite gene sharing:

(show all 24)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.88 CCL2 CCL5 CCR5 IL5
2 immune system process GO:0002376 9.85 EIF2AK4 FGA IRF7 OAS1 RSAD2
3 MAPK cascade GO:0000165 9.83 CCL2 CCL5 CCR5 IL5
4 viral process GO:0016032 9.83 CCR5 EIF2AK4 IRF7 RSAD2 STAT1
5 cytokine-mediated signaling pathway GO:0019221 9.78 CCL2 IL1RL1 IL5
6 chemokine-mediated signaling pathway GO:0070098 9.69 CCL2 CCL5 CCR5
7 interferon-gamma-mediated signaling pathway GO:0060333 9.67 IRF7 OAS1 STAT1
8 chemotaxis GO:0006935 9.67 CCL2 CCL5 CCR5 IL4
9 response to cytokine GO:0034097 9.65 CCL5 IL4 STAT1
10 negative regulation of endothelial cell apoptotic process GO:2000352 9.62 FGA IL4
11 response to tumor necrosis factor GO:0034612 9.61 CCL2 CCL5
12 cellular protein complex assembly GO:0043623 9.6 CCL5 FGA
13 positive regulation of defense response to virus by host GO:0002230 9.59 EIF2AK4 IL4
14 positive regulation of JAK-STAT cascade GO:0046427 9.58 CCL5 IL5
15 positive regulation of monocyte chemotaxis GO:0090026 9.57 CCL2 CCL5
16 dendritic cell chemotaxis GO:0002407 9.56 CCL5 CCR5
17 response to virus GO:0009615 9.56 CCL5 IRF7 OAS1 RSAD2
18 positive regulation of macrophage chemotaxis GO:0010759 9.55 CCL2 CCL5
19 macrophage chemotaxis GO:0048246 9.54 CCL2 CCL5
20 negative regulation of viral genome replication GO:0045071 9.5 CCL5 OAS1 RSAD2
21 type I interferon signaling pathway GO:0060337 9.46 IRF7 OAS1 RSAD2 STAT1
22 negative regulation of macrophage apoptotic process GO:2000110 9.4 CCL5 IRF7
23 defense response to virus GO:0051607 9.35 EIF2AK4 IRF7 OAS1 RSAD2 STAT1
24 immune response GO:0006955 9.17 CCL2 CCL5 CCR5 IL1RL1 IL4 IL5

Molecular functions related to Yellow Fever according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 phosphatidylinositol phospholipase C activity GO:0004435 8.96 CCL5 CCR5
2 cytokine activity GO:0005125 8.92 CCL2 CCL5 IL4 IL5

Sources for Yellow Fever

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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