MCID: 1CH001
MIFTS: 22

1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Categories: Immune diseases, Skin diseases

Aliases & Classifications for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

MalaCards integrated aliases for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis:

Name: 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis 12 15
Allergic Contact Dermatitis to Dinitrochlorobenzene 12
Allergic Contact Dermatitis to Dncb 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040069

Summaries for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Disease Ontology : 12 An allergic contact dermatitis that has_allergic_trigger 1-chloro-2,4-dinitrobenzene.

MalaCards based summary : 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis, also known as allergic contact dermatitis to dinitrochlorobenzene, is related to dermatitis and contact dermatitis. An important gene associated with 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis is IL4 (Interleukin 4), and among its related pathways/superpathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and Immune response NFAT in immune response.

Related Diseases for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Diseases related to 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 57, show less)
# Related Disease Score Top Affiliating Genes
1 dermatitis 10.2
2 contact dermatitis 10.2
3 allergic contact dermatitis 10.2
4 virus associated hemophagocytic syndrome 9.9 IL2 IL4
5 autoimmune vasculitis 9.9 IL2 IL4
6 jak3-deficient severe combined immunodeficiency 9.9 IL2 IL4
7 severe combined immunodeficiency 9.9 IL2 IL4
8 atopic keratoconjunctivitis 9.9 IL2 IL4
9 keratoconjunctivitis 9.9 IL2 IL4
10 conjunctivitis 9.9 IL2 IL4
11 angiostrongyliasis 9.9 IL2 IL4
12 gaucher disease, type ii 9.9 IL2 IL4
13 autoimmune gastritis 9.9 IL2 IL4
14 vulvovaginal candidiasis 9.9 IL2 IL4
15 coccidiosis 9.9 IL2 IL4
16 severe combined immunodeficiency, x-linked 9.9 IL2 IL4
17 vernal conjunctivitis 9.9 IL2 IL4
18 aphthous stomatitis 9.9 IL2 IL4
19 acute graft versus host disease 9.9 IL2 IL4
20 onchocerciasis 9.9 IL2 IL4
21 autoimmune uveitis 9.9 IL2 IL4
22 paracoccidioidomycosis 9.9 IL2 IL4
23 parasitic helminthiasis infectious disease 9.9 IL2 IL4
24 brucellosis 9.9 IL2 IL4
25 tonsillitis 9.9 IL2 IL4
26 parasitic protozoa infectious disease 9.9 IL2 IL4
27 autoimmune disease of musculoskeletal system 9.9 IL2 IL4
28 autoimmune disease 9.9 IL2 IL4
29 autoimmune disease of central nervous system 9.9 IL2 IL4
30 primary bacterial infectious disease 9.9 IL2 IL4
31 immune deficiency disease 9.9 IL2 IL4
32 leukocyte disease 9.9 IL2 IL4
33 visceral leishmaniasis 9.9 IL2 IL4
34 bone inflammation disease 9.9 IL2 IL4
35 toxic shock syndrome 9.9 IL2 IL4
36 sezary's disease 9.9 IL2 IL4
37 schistosomiasis 9.9 IL2 IL4
38 trypanosomiasis 9.9 IL2 IL4
39 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 9.9 IL2 IL4
40 cutaneous t cell lymphoma 9.9 IL2 IL4
41 tetanus 9.9 IL2 IL4
42 pulmonary tuberculosis 9.8 IL2 IL4
43 myasthenia gravis 9.8 IL2 IL4
44 respiratory system disease 9.8 IL2 IL4
45 immune system disease 9.8 IL2 IL4
46 measles 9.8 IL2 IL4
47 viral infectious disease 9.8 IL2 IL4
48 dermatitis, atopic 9.8 IL2 IL4
49 colitis 9.8 IL2 IL4
50 lymphocytic leukemia 9.8 IL2 IL4
51 common variable immunodeficiency 9.8 IL2 IL4
52 inflammatory bowel disease 9.7 IL2 IL4
53 aplastic anemia 9.7 IL2 IL4
54 renal cell carcinoma, nonpapillary 9.7 IL2 IL4
55 rheumatoid arthritis 9.7 IL2 IL4
56 multiple sclerosis 9.6 IL2 IL4
57 leukemia, chronic lymphocytic 9.5 IL2 IL4

Graphical network of the top 20 diseases related to 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis:



Diseases related to 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Symptoms & Phenotypes for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Drugs & Therapeutics for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Search Clinical Trials , NIH Clinical Center for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Genetic Tests for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Anatomical Context for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Publications for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Articles related to 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis:

(showing 1, show less)
# Title Authors Year
1
Inhibition of allergic contact dermatitis to DNCB but not to oxazolone in interleukin-4-deficient mice. ( 10201532 )
1999

Variations for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Expression for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Search GEO for disease gene expression data for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis.

Pathways for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Pathways related to 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis according to GeneCards Suite gene sharing:

(showing 24, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 IL2 IL4
2
Show member pathways
12.16 IL2 IL4
3
Show member pathways
12.13 IL2 IL4
4
Show member pathways
12.1 IL2 IL4
5 12.09 IL2 IL4
6
Show member pathways
12.04 IL2 IL4
7
Show member pathways
11.96 IL2 IL4
8
Show member pathways
11.92 IL2 IL4
9
Show member pathways
11.87 IL2 IL4
10
Show member pathways
11.79 IL2 IL4
11
Show member pathways
11.61 IL2 IL4
12 11.59 IL2 IL4
13 11.56 IL2 IL4
14
Show member pathways
11.53 IL2 IL4
15 11.37 IL2 IL4
16 11.34 IL2 IL4
17
Show member pathways
11.28 IL2 IL4
18 11.22 IL2 IL4
19
Show member pathways
11.15 IL2 IL4
20 10.92 IL2 IL4
21 10.75 IL2 IL4
22 10.67 IL2 IL4
23 10.42 IL2 IL4
24 10.04 IL2 IL4

GO Terms for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

Biological processes related to 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis according to GeneCards Suite gene sharing:

(showing 8, show less)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.43 IL2 IL4
2 regulation of signaling receptor activity GO:0010469 9.4 IL2 IL4
3 cytokine-mediated signaling pathway GO:0019221 9.37 IL2 IL4
4 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.32 IL2 IL4
5 positive regulation of T cell proliferation GO:0042102 9.26 IL2 IL4
6 positive regulation of B cell proliferation GO:0030890 9.16 IL2 IL4
7 positive regulation of T cell differentiation GO:0045582 8.96 IL2 IL4
8 positive regulation of isotype switching to IgG isotypes GO:0048304 8.62 IL2 IL4

Molecular functions related to 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.96 IL2 IL4
2 growth factor activity GO:0008083 8.62 IL2 IL4

Sources for 1-Chloro-2,4-Dinitrobenzene Allergic Contact Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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