Aliases & Classifications for 47,xyy

MalaCards integrated aliases for 47,xyy:

Name: 47,xyy 74
Xyy Syndrome 74 52 25 58
Double Y Syndrome 52 58 29
47,xyy Syndrome 52 25 58
47, Xyy Syndrome 52 71
Xyy Karyotype 52 25
Yy Syndrome 52 25
Y Disomy 52 58
Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome 71
Jacob's Syndrome 25
Jacobs Syndrome 52
Disomy Y 52
Double Y 52

Characteristics:

Orphanet epidemiological data:

58
47,xyy syndrome
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 58  
Developmental anomalies during embryogenesis


Summaries for 47,xyy

Genetics Home Reference : 25 47,XYY syndrome is characterized by an extra copy of the Y chromosome in each of a male's cells. Although many males with this condition are taller than average, the chromosomal change sometimes causes no unusual physical features. Most males with 47,XYY syndrome have normal production of the male sex hormone testosterone and normal sexual development, and they are usually able to father children. 47,XYY syndrome is associated with an increased risk of learning disabilities and delayed development of speech and language skills. Affected boys can have delayed development of motor skills (such as sitting and walking) or weak muscle tone (hypotonia). Other signs and symptoms of this condition include hand tremors or other involuntary movements (motor tics), seizures, and asthma. Males with 47,XYY syndrome have an increased risk of behavioral, social, and emotional difficulties compared with their unaffected peers. These problems include attention-deficit/hyperactivity disorder (ADHD); depression; anxiety; and autism spectrum disorder, which is a group of developmental conditions that affect communication and social interaction. Physical features related to 47,XYY syndrome can include increased belly fat, a large head (macrocephaly), unusually large teeth (macrodontia), flat feet (pes planus), fifth fingers that curve inward (clinodactyly), widely spaced eyes (ocular hypertelorism), and abnormal side-to-side curvature of the spine (scoliosis). These characteristics vary widely among affected boys and men.

MalaCards based summary : 47,xyy, also known as xyy syndrome, is related to turner syndrome and camptodactyly-arthropathy-coxa vara-pericarditis syndrome. An important gene associated with 47,xyy is IGFBP3 (Insulin Like Growth Factor Binding Protein 3). The drugs Metformin and Entecavir have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and lung, and related phenotypes are malar flattening and low-set ears

NIH Rare Diseases : 52 47, XYY syndrome is a syndrome (group of signs and symptoms) that affects males. For some males with this syndrome, signs and symptoms are barely noticeable. For others, signs and symptoms may include learning disabilities , speech delay , low muscle tone (hypotonia ), and being taller than expected. 47, XYY syndrome is caused by having an extra copy of the Y chromosome in every cell of the body. The syndrome is usually not inherited . Diagnosis can be made based on prenatal tests, or it may occur during childhood or adulthood if a male has signs or symptoms of the disease. Management may include special education as well as intervention or therapies for developmental delays .

Wikipedia : 74 XYY syndrome is a genetic condition in which a male has an extra Y chromosome. Symptoms are usually few.... more...

Related Diseases for 47,xyy

Diseases related to 47,xyy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
# Related Disease Score Top Affiliating Genes
1 turner syndrome 28.8 SRY IGFBP3
2 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 11.6
3 creutzfeldt-jakob disease 11.2
4 47, xxy 10.6
5 azoospermia 10.3
6 tooth size 10.3
7 infertility 10.3
8 autism 10.2
9 autism spectrum disorder 10.2
10 hypogonadotropic hypogonadism 10.2
11 male infertility 10.2
12 hypogonadism 10.2
13 hypogonadotropism 10.2
14 hair whorl 10.1
15 attention deficit-hyperactivity disorder 10.1
16 hypertelorism 10.1
17 down syndrome 10.1
18 cryptorchidism, unilateral or bilateral 10.1
19 oligospermia 10.1
20 gonadal dysgenesis 10.1
21 learning disability 10.1
22 hypotonia 10.1
23 tremor 10.1
24 chromosomal triplication 10.1
25 radioulnar synostosis 10.0
26 synostosis 10.0
27 microcephaly 10.0
28 lipoid congenital adrenal hyperplasia 10.0
29 constricting bands, congenital 10.0
30 brachydactyly 10.0
31 oligohydramnios 10.0
32 agammaglobulinemia 10.0
33 tic disorder 10.0
34 olfactory neuroblastoma 10.0
35 neuroblastoma 10.0
36 pulmonary embolism 10.0
37 neurofibromatosis, type ii 10.0
38 elastosis perforans serpiginosa 10.0
39 nondisjunction 10.0
40 noonan syndrome 1 10.0
41 schizophrenia 10.0
42 chromosome 2q35 duplication syndrome 10.0
43 syndactyly, type iii 10.0
44 hydrops fetalis, nonimmune 10.0
45 hypogonadism, male 10.0
46 taurodontism 10.0
47 testes, rudimentary 10.0
48 46,xx sex reversal 1 10.0
49 pituitary adenoma, prolactin-secreting 10.0
50 leukemia, acute myeloid 10.0

Graphical network of the top 20 diseases related to 47,xyy:



Diseases related to 47,xyy

Symptoms & Phenotypes for 47,xyy

Human phenotypes related to 47,xyy:

58 31 (show all 34)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 malar flattening 58 31 hallmark (90%) Very frequent (99-80%) HP:0000272
2 low-set ears 58 31 hallmark (90%) Very frequent (99-80%) HP:0000369
3 delayed speech and language development 58 31 hallmark (90%) Very frequent (99-80%) HP:0000750
4 motor delay 58 31 hallmark (90%) Very frequent (99-80%) HP:0001270
5 tall stature 58 31 hallmark (90%) Very frequent (99-80%) HP:0000098
6 macrocephaly 58 31 frequent (33%) Frequent (79-30%) HP:0000256
7 hypertelorism 58 31 frequent (33%) Frequent (79-30%) HP:0000316
8 intellectual disability 58 31 frequent (33%) Frequent (79-30%) HP:0001249
9 neonatal hypotonia 58 31 frequent (33%) Frequent (79-30%) HP:0001319
10 attention deficit hyperactivity disorder 58 31 frequent (33%) Frequent (79-30%) HP:0007018
11 specific learning disability 58 31 frequent (33%) Frequent (79-30%) HP:0001328
12 impaired social interactions 58 31 frequent (33%) Frequent (79-30%) HP:0000735
13 asthma 58 31 frequent (33%) Frequent (79-30%) HP:0002099
14 congenital stationary night blindness 58 31 frequent (33%) Frequent (79-30%) HP:0007642
15 finger clinodactyly 58 31 frequent (33%) Frequent (79-30%) HP:0040019
16 impulsivity 58 31 frequent (33%) Frequent (79-30%) HP:0100710
17 hydrocephalus 58 31 occasional (7.5%) Occasional (29-5%) HP:0000238
18 seizures 58 31 occasional (7.5%) Occasional (29-5%) HP:0001250
19 macroorchidism 58 31 occasional (7.5%) Occasional (29-5%) HP:0000053
20 cryptorchidism 58 31 occasional (7.5%) Occasional (29-5%) HP:0000028
21 increased circulating gonadotropin level 58 31 occasional (7.5%) Occasional (29-5%) HP:0000837
22 hypospadias 58 31 occasional (7.5%) Occasional (29-5%) HP:0000047
23 micropenis 58 31 occasional (7.5%) Occasional (29-5%) HP:0000054
24 abnormality of brainstem morphology 58 31 occasional (7.5%) Occasional (29-5%) HP:0002363
25 azoospermia 58 31 occasional (7.5%) Occasional (29-5%) HP:0000027
26 oligospermia 58 31 occasional (7.5%) Occasional (29-5%) HP:0000798
27 male infertility 58 31 occasional (7.5%) Occasional (29-5%) HP:0003251
28 dysgenesis of the cerebellar vermis 58 31 occasional (7.5%) Occasional (29-5%) HP:0002195
29 cerebellar dysplasia 58 31 occasional (7.5%) Occasional (29-5%) HP:0007033
30 increased serum testosterone level 58 31 occasional (7.5%) Occasional (29-5%) HP:0030088
31 varicocele 58 31 occasional (7.5%) Occasional (29-5%) HP:0012871
32 behavioral abnormality 58 Frequent (79-30%)
33 hyperactivity 58 Frequent (79-30%)
34 autistic behavior 58 Occasional (29-5%)

GenomeRNAi Phenotypes related to 47,xyy according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 8.62 IGFBP3 SRY

Drugs & Therapeutics for 47,xyy

Drugs for 47,xyy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 815)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 4091 14219
2
Entecavir Approved, Investigational Phase 4 142217-69-4 153941
3
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
4
Bivalirudin Approved, Investigational Phase 4 128270-60-0 16129704
5
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
6
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610
7
Tranexamic Acid Approved Phase 4 1197-18-8 5526
8
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
9
Tetracaine Approved, Vet_approved Phase 4 94-24-6 5411
10
Glimepiride Approved Phase 4 93479-97-1 3476
11
Gliclazide Approved Phase 4 21187-98-4 3475
12
Glyburide Approved Phase 4 10238-21-8 3488
13
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
14
Racepinephrine Approved Phase 4 329-65-7 838
15
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
16
Ciclesonide Approved, Investigational Phase 4 141845-82-1, 126544-47-6 444033
17
Histamine Approved, Investigational Phase 4 51-45-6 774
18
Insulin glargine Approved Phase 4 160337-95-1
19
Tinidazole Approved, Investigational Phase 4 19387-91-8 5479
20
Rabeprazole Approved, Investigational Phase 4 117976-89-3 5029
21
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
22
Modafinil Approved, Investigational Phase 4 68693-11-8 4236
23
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
24
Lixisenatide Approved Phase 4 320367-13-3
25
Abciximab Approved Phase 4 143653-53-6
26
Haloperidol Approved Phase 4 52-86-8 3559
27
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
28
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
29
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
30
Morphine Approved, Investigational Phase 4 57-27-2 5288826
31
Ribavirin Approved Phase 4 36791-04-5 37542
32
Nystatin Approved, Vet_approved Phase 4 1400-61-9 11953884
33
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
34
Remifentanil Approved Phase 4 132875-61-7 60815
35
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
36
Peginterferon alfa-2a Approved, Investigational Phase 4 198153-51-4 5360545
37
Oxymetazoline Approved, Investigational Phase 4 1491-59-4 4636
38
Phenylephrine Approved Phase 4 59-42-7 6041
39
Atropine Approved, Vet_approved Phase 4 51-55-8, 5908-99-6 174174
40
Adenosine Approved, Investigational Phase 4 58-61-7 60961
41
Ondansetron Approved Phase 4 99614-02-5 4595
42
Norepinephrine Approved Phase 4 51-41-2 439260
43
Timolol Approved Phase 4 26839-75-8 33624 5478
44
Bimatoprost Approved, Investigational Phase 4 155206-00-1 5311027
45
Brinzolamide Approved Phase 4 138890-62-7 68844
46
Dorzolamide Approved Phase 4 120279-96-1 5284549 3154
47
Latanoprost Approved, Investigational Phase 4 130209-82-4 5282380 5311221
48
Travoprost Approved Phase 4 157283-68-6 5282226
49
Ephedrine Approved Phase 4 299-42-3 9294
50
Pseudoephedrine Approved Phase 4 90-82-4 7028

Interventional clinical trials:

(show top 50) (show all 1044)
# Name Status NCT ID Phase Drugs
1 Clinical Trial Program of a Medical Instrument Product Unknown status NCT01157455 Phase 4 Aspirin;Clopidogrel;Heparin or Bivalirudin
2 Randomized Phase IV Trial to Compare Cetuximab With Concomitant Radiation Therapy With Concomitant Mitomycin-C and 5-Fluorouracil With Radiation Therapy for Locally Advanced Squamous Cell Carcinomas of the Head and Neck Unknown status NCT02015650 Phase 4 Cetuximab;Mitomycin-C/ 5-Fluorouracil
3 Phase IV Study of the Efficacy of Entecavir in Patients With Chronic Hepatitis B Virus Infection and Persistently Normal Alanine Aminotransferase Unknown status NCT01833611 Phase 4 Entecavir;placebo
4 Cross-reactivity and Tolerability of Ertapenem in Patients With IgE-mediated Allergy to Beta-lactams Unknown status NCT01159379 Phase 4 ertapenem
5 Minimization of Bleeding Complications Through Utilization of Perioperative Tranexamic Acid in Breast Surgery: A Randomized Double-blinded Placebo-controlled Trial Unknown status NCT02615366 Phase 4 Tranexamic Acid;Placebo
6 Pulpal Blood Flow With the Use of Intra-nasal Anesthetic: a Randomized Double-blind Crossover Study Unknown status NCT03368391 Phase 4 tetracaine HCl and oxymetazoline HCL;2% Lidocaine with 1:100,000 epinephrine;3% Mepivacaine with 1:100,000 epinephrine;saline intranasal;saline infiltration
7 A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE SUPPLEMENTATION WITH KIOLIC® IN PATIENTS WITH DIAGNOSIS OF METABOLIC SYNDROME TO IMPROVE ENDOTHELIAL FUNCTION AND INFLAMMATORY STATE. "KYMES" Unknown status NCT01168700 Phase 4 aged garlic extract;Placebo
8 Effects on Incidence of Cardiovascular Events of the Addition of Pioglitazone as Compared With a Sulphonylurea in Type 2 Diabetic Patients Inadequately Controlled With Metformin. Unknown status NCT00700856 Phase 4 add-on pioglitazone;add-on sulphonylurea
9 Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women With PCOS Completed NCT03644212 Phase 4 Vitamin D3
10 Phase 4 Cost-effectiveness Study of Beclomethasone Versus Ciclesonide as Controller Medications in Pediatric Asthma in a Hospital in Bogotá Completed NCT01333800 Phase 4 Beclomethasone;Ciclesonide
11 A Phase IV Open, Randomized, Controlled Study to Evaluate the Safety and Immunogenicity of a Pediatric Presentation (0.25 ml) of the Virosomal Hepatitis A Virus (HAV) Vaccine HAVpur in Healthy Young Children Aged Between and Including 18 Months to 47 Months, Using a 0/6 Month Immunization Schedule Completed NCT01349829 Phase 4
12 Modified Non-clarithromycin Triple Therapy in Eradicating Helicobacter Pylori Completed NCT02776371 Phase 4 Modified non-clarithromycin triple therapy;Sequential therapy
13 Study of the Effect of Calcifediol Supplementation on Left Ventricular Function in Cardiopathic Patients Undergoing Major Orthopedic Surgery. Completed NCT03403933 Phase 4 Didrogyl
14 A Randomized, Multicenter, Open-Label, Parallel-Group, 28 Days Phase IV Study Comparing The Postprandial Plasma Glucose Profile of Lixisenatide With That of Sitagliptin Add-On to Insulin Glargine in Type 2 Diabetes Mellitus Completed NCT02200991 Phase 4 LIXISENATIDE AVE0010;Sitagliptin;Insulin glargine HOE901
15 Reveal® XT Performance Trial Completed NCT00680927 Phase 4
16 Respiratory Muscle Stretching in Patients With Chronic Obstructive Pulmonary Disease Submitted a Pulmonary Rehabilitation Program Completed NCT00935181 Phase 4
17 Anti-inflammatory Effects of Intracoronary and Intravenous Abciximab Administration During Primary Percutaneous Coronary Intervention.(Molecole di Adesione Nella Sindrome Coronarica Acuta Completed NCT01757457 Phase 4 Intracoronary administration of an abciximab bolus during primary PCI;Intravenous administration of an abciximab bolus during primary PCI
18 Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol IM Injection for Treatment of Acute Psychotic Agitation in Schizophrenia Completed NCT00859872 Phase 4 risperidone oral solution;haloperidol
19 A Feasibility Study: Understanding and Altering Pain Expectations in Subjects With Osteoarthritis of the Knee or Hip Completed NCT02155257 Phase 4 Modafinil;Gabapentin;Placebo
20 Oral Nystatin Prophylaxis to Prevent Systemic Fungal Infection in Very Low Birth Weight Preterm Infants: a Randomized Controlled Trial Completed NCT03390374 Phase 4 Nystatin Oral
21 The Effect of Prior Short Course Combination Antiretroviral Therapy Administered for the Prevention of Mother-to-Child Transmission (pMTCT) of HIV-1 on Subsequent Treatment Efficacy in Treatment-"Nearly Naive" Participants Completed NCT00442962 Phase 4 Efavirenz;Emtricitabine/Tenofovir disoproxil fumarate
22 Chronic Obstructive Pulmonary Disease and Weaning From Mechanical Ventilation in Difficult to Wean Patients; Randomized Prospective Study Completed NCT00355732 Phase 4
23 Target-controlled Infusion of Propofol and Remifentanil During General Anaesthesia Guided by Entropy of the Electroencephalogram: Comparison Between Manual Perfusion and Automated Perfusion Completed NCT00391885 Phase 4
24 Prospective Randomized Trial to Evaluate the Efficacy of Donor Preconditioning With Dopamine on Initial Graft Function After Kidney Transplantation Completed NCT00115115 Phase 4 Dopamine infusion to brain dead organ donors
25 Prospective, Randomized Clinical Trial,to Compare Standard Trabeculectomy to the Ex-PRESS Mini Glaucoma Shunt Implantation Under a Scleral Flap in Eyes With Open-Angle Glaucoma Completed NCT00698438 Phase 4
26 A New Strategy Regarding Discontinuation of Dual Antiplatelet; Real Safety and Efficacy of a 3-month Dual Antiplatelet Therapy Following Zotarolimus-eluting Stents Implantation (RESET Trial) Completed NCT01145079 Phase 4
27 A Randomized Trial Comparing Daily Atropine Versus Weekend Atropine Completed NCT00094614 Phase 4 Atropine
28 The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment Completed NCT03121521 Phase 4 Melatonin 10 mg;Placebo
29 ADenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination: the ADVICE Trial Completed NCT01058980 Phase 4
30 Comparison of the Effect of Fluoride Remineralizer Gel and Foam: a Randomized Clinical Trial Completed NCT02490592 Phase 4
31 Choroidal Thickness and Its Correlations With Ocular Parameters in Cases With Primary Open-angle Glaucoma Completed NCT03966560 Phase 4 Brimonidine Tartrate;Dorzolamide (as Dorzolamide Hydrochloride) 20 Mg/mL and Timolol (as Timolol Maleate) 5 Mg/mL Eye Drops;Brinzolamide/Timolol 10 MG/1 ML-5 MG/1 ML Ophthalmic Suspension;Travoprost and Timolol;Bimatoprost and Timolol;Latanoprost
32 Effect of Aspirin Intake on Awakening Versus at Bedtime on Circadian Rhythm of Platelet Reactivity in Healthy Subjects Completed NCT01900639 Phase 4
33 Crystalloid Coload Combined With Variable Rate Phenylephrine Infusion for Prevention of Hypotension During Spinal Anesthesia for Elective Cesarean Delivery vs Crystalloid Coload Alone Completed NCT01378325 Phase 4 Phenylephrine;saline
34 Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules Completed NCT02765763 Phase 4 2-Minute Reveal Masque;24/7 Barrier Repair Cream;8-in-1 BioSerum;Null Formula 2-Minute Reveal Masque;Null Formula 24/7 Barrier Repair Cream;Null Formula 8-in-1 BioSerum
35 A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study Evaluating the Pharmacodynamic Effect of a 6-week Treatment With Triamcinolone Acetonide Aqueous Nasal Spray 110 μg and 220 μg Once Daily on Basal Hypothalamic-Pituitary-Adrenal (HPA) Axis Function in Children [>=2 to < 12 Years of Age] With Allergic Rhinitis (AR). Completed NCT01154153 Phase 4 Placebo nasal spray;Triamcinolone acetonide aqueous (TAA-AQ) nasal spray (NASACORT AQ);Placebo nasal spray;Claritin® Syrup
36 Patient-controlled Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis Completed NCT02669004 Phase 4 Intermittent bolus epidural morphine;continuous epidural morphine
37 Impact of Dexmedetomidine on the Incidence of Postoperative Delirium in Patients After Cardiac Surgery: a Randomized, Double-blinded, and Placebo-controlled Clinical Trial Completed NCT02267538 Phase 4 dexmedetomidine hydrochloride for injection;0.9% sodium chloride for injection
38 Randomized Trial of 24 or 48 Weeks of Peginterferon Alfa-2a Plus Ribavirin for Chronic Hepatitis C Virus Genotype 1-infected Patients in Taiwan Completed NCT00495131 Phase 4 Pegylated interferon alfa-2a plus ribavirin;Pegylated interferon alfa-2a plus ribavirin
39 Incontinence & Intimate Partners: Assessing the Contribution of Treatment Completed NCT01559389 Phase 4 Solifenacin
40 Effects of Anemia Correction on Vascular Function, Endothelial Cell Markers and Monocyte Apoptosis in Renal Transplant Recipients Completed NCT00204334 Phase 4 darbopoeitin
41 Effectiveness and Safety of Inactivated EV71 Vaccine (Human Diploid Cell) in 6-71 Months Children: an Open-label Controlled Phase Ⅳ Clinical Study Completed NCT03001986 Phase 4
42 Prospective, Randomized Clinical Trial of a Silver Eluting Dressing System for Prevention of Lower Extremity Revascularization Wound Complications Completed NCT01229358 Phase 4
43 Nasally Inhaled Isopropyl Alcohol Versus Oral Ondansetron for the Treatment of Nausea in the Emergency Department: A Double-Blind Randomized Controlled Trial Completed NCT02760069 Phase 4 Inhaled isopropyl alcohol;Oral ondansetron;Inhaled normal saline;Oral placebo
44 Study of Methylphenidate to Treat Gait Disorders And Attention Deficit In Parkinson's Disease: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentric Trial Completed NCT00914095 Phase 4 methylphenidate;placebo
45 Nicotine Replacement Therapy Added to Cognitive Behavioral Therapy for Smoking Cessation in Patients With Major Mental Illness Completed NCT00320723 Phase 4 bupropion, transdermal nicotine patch
46 Effects of Eplerenone on Left Ventricular Hypertrophy in Patients With Resistant Hypertension and Obstructive Sleep Apnoea Completed NCT03186742 Phase 4 Eplerenone 50 mg Tab
47 Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP Completed NCT01404689 Phase 4 Dexmedetomidine
48 Phase 4 Study of Primary Use of the Vacuum Assisted Laparostomy in Treatment of Severe Peritonitis Completed NCT01531543 Phase 4
49 A Randomized Trial of Deep Neuromuscular Blockade Reversed With Sugammadex Versus Moderate Neuromuscular Block Reversed With Neostigmine, on Postoperative Quality of Recovery Completed NCT03034577 Phase 4 Sugammadex;Neostigmine
50 Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) : Pattern Electroretinography Study Completed NCT03046693 Phase 4 Group A Citicoline 1000 mg oral tablet;Group B placebo oral tablet

Search NIH Clinical Center for 47,xyy

Genetic Tests for 47,xyy

Genetic tests related to 47,xyy:

# Genetic test Affiliating Genes
1 Double Y Syndrome 29

Anatomical Context for 47,xyy

MalaCards organs/tissues related to 47,xyy:

40
Breast, Testes, Lung, Liver, Bone, Heart, Brain

Publications for 47,xyy

Articles related to 47,xyy:

(show top 50) (show all 30000)
# Title Authors PMID Year
1
Clinical aspects of infertile 47,XYY patients: a retrospective study. 52 61
28715980 2019
2
Oral, physical, and behavioral aspects of patient with chromosome 47, XYY syndrome. 61 52
26381641 2015
3
Positive effects of early androgen therapy on the behavioral phenotype of boys with 47,XXY. 61 52
25939399 2015
4
Impact of forest cover and conservation agriculture on sediment export: A case study in a montane reserve, south-western China. 61
31733551 2020
5
Evaluation of astringent taste of green tea through mass spectrometry-based targeted metabolic profiling of polyphenols. 61
31622805 2020
6
Factors Associated With Fast Recovery of Bell Palsy in Children. 61
31623512 2020
7
Emotion regulation in adults with Klinefelter syndrome (47,XXY): Neurocognitive underpinnings and associations with mental health problems. 61
31593332 2020
8
Validation of IRDFF-II library by means of 252Cf spectral averaged cross sections. 61
31655353 2020
9
Phoneutria toxin PnTx3-5 inhibits TRPV1 channel with antinociceptive action in an orofacial pain model. 61
31647972 2020
10
Occurrence and congener profiles of polybrominated diphenyl ethers in green mussels (Perna viridis) collected from northern South China Sea and the associated potential health risk. 61
31514028 2020
11
Weight Status and Sedentary Behavior of Alzheimer's Disease Caregivers. 61
31783927 2020
12
The utility of the delphi method in defining anastomotic leak following colorectal surgery. 61
31164194 2020
13
A prospective study of opioid use for postoperative pain management after breast operation. 61
31375247 2020
14
Role of Viral Molecular Panels in Diagnosing the Etiology of Fever in Infants Younger Than 3 Months. 61
31709801 2020
15
The Role of Perceived Legitimacy and Its Effect on Prison Adaptation: A Longitudinal Study on a Chinese Juvenile Prison. 61
31470755 2020
16
The impact of perceived heat stress symptoms on work-related tasks and social factors: A cross-sectional survey of Australia's Monsoonal North. 61
31473500 2020
17
"Waste"-ing away: Presence of Cu ions influences microbial degradation kinetics and metabolite formation of the prevalent brominated flame retardant BDE-47. 61
31791515 2020
18
Spontaneous Coronary Artery Dissection and Its Association With Fibromuscular Dysplasia and Other Vascular Abnormalities. 61
31706452 2020
19
Anatomic Variation of the Phrenic Nerve and Brachial Plexus Encountered during 100 Supraclavicular Decompressions for Neurogenic Thoracic Outlet Syndrome with Associated Postoperative Neurologic Complications. 61
31207398 2020
20
​Venous anomalies in renal transplantation: an accessory left-sided IVC in a live kidney donor. 61
31848141 2019
21
Hard-Sphere Random Close-Packed Au47Cd2(TBBT)31 Nanoclusters with a Faradaic Efficiency of Up to 96% for Electrocatalytic CO2 Reduction to CO. 61
31834651 2019
22
Insights into the Phycobilisome Interaction with the Photosystem II and Orange Carotenoid Protein. 61
31799708 2019
23
Retrospective evaluation of anesthetic techniques in pregnant women with renal transplantation 61
31655526 2019
24
Hantavirus Antibodies among Phyllostomid Bats from the Arc of Deforestation in Southern Amazonia, Brazil. 61
31793244 2019
25
Non-cystic Sclerosing Polycystic Adenosis: Diagnosis of a Hitherto Undescribed Pattern. 61
30361835 2019
26
PD-1 and PD-L1 Expression in Osteosarcoma: Which Specimen to Evaluate? 61
31842180 2019
27
Progressive myeloneuropathy with symptomatic anaemia. 61
31796451 2019
28
Effect of Euphorbia factor L1 on intestinal barrier impairment and defecation dysfunction in Caenorhabditis elegans. 61
31654989 2019
29
A Machine Learning-Based QSAR Model for Benzimidazole Derivatives as Corrosion Inhibitors by Incorporating Comprehensive Feature Selection. 61
31486019 2019
30
Effects of different constants and standards on the reproducibility of carbonate clumped isotope (Δ47 ) measurements: Insights from a long-term dataset. 61
31814194 2019
31
Pulmonary Artery Resection During Lung Resection for Malignancy. 61
31336066 2019
32
CCL5 protein level: influence on breast cancer staging and lymph nodes commitment. 61
31691056 2019
33
Long-term Outcomes of Balloon Dilation for Persistent Eustachian Tube Dysfunction. 61
31385858 2019
34
Metronidazole-induced encephalopathy caused by hyperbaric oxygen therapy in a patient with mandibular osteomyelitis. 61
31204183 2019
35
Reinterventions after freestyle stentless aortic valve replacement: an assessment of procedural risks. 61
31424504 2019
36
Carcinoma Cuniculatum of the Alveolar Mucosa: A Rare Variant of Squamous Cell Carcinoma. 61
29948589 2019
37
Serum sphingosine-1-phosphate levels in bladder pain syndrome/interstitial cystitis patients: could it help in diagnosis? 61
31792578 2019
38
Subconjunctival haemorrhage in 147 dogs. 61
31691298 2019
39
Hepatitis C Co-infection and Mortality in People Living with HIV in Middle Tennessee. 61
31789047 2019
40
MRI Tumor Regression Grade and Circulating Tumor DNA as Complementary Tools to Assess Response and Guide Therapy Adaptation in Rectal Cancer. 61
31852830 2019
41
FBXO47 regulates telomere-inner nuclear envelope integration by stabilizing TRF2 during meiosis. 61
31724724 2019
42
Cerebrovascular Pulsatility During Rest and Exercise Reflects Hemodynamic Impairment in Stroke and Cerebral Small Vessel Disease. 61
31570171 2019
43
Use of percutaneous microwave ablation for the treatment of bone tumors: a retrospective study of clinical outcomes in 47 patients. 61
31849340 2019
44
The bioaccumulation, elimination, and trophic transfer of BDE-47 in the aquatic food chain of Chlorella pyrenoidosa-Daphnia magna. 61
31831226 2019
45
Hormonal replacement therapy and its potential influence on working memory and competency/adaptive functioning in 47,XXY (Klinefelter syndrome). 61
31577063 2019
46
Serine-47 phosphorylation of cytochrome c in the mammalian brain regulates cytochrome c oxidase and caspase-3 activity. 61
31570002 2019
47
Hemispherectomy in adults and adolescents: Seizure and functional outcomes in 47 patients. 61
31677151 2019
48
Testosterone Treatment in Infants With 47,XXY: Effects on Body Composition. 61
31737857 2019
49
Prehypertension and risk of cardiovascular diseases: a meta-analysis of 47 cohort studies. 61
31335511 2019
50
Low-quality Evidence Suggests Digital Impressions (DIs) and Conventional Impressions Are Comparable for Marginal and Internal Fit, Very-low Quality Evidence for Interproximal and Occlusal Contacts is Insufficient to Draw Conclusion and There Is No Evidence Regarding Survival of Full-coverage Restorations. 61
31843174 2019

Variations for 47,xyy

Expression for 47,xyy

Search GEO for disease gene expression data for 47,xyy.

Pathways for 47,xyy

GO Terms for 47,xyy

Sources for 47,xyy

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68 SNOMED-CT via HPO
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72 UMLS via Orphanet
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