Aliases & Classifications for 47,xyy

MalaCards integrated aliases for 47,xyy:

Name: 47,xyy 75
Xyy Syndrome 75 53 25 59
Double Y Syndrome 53 59 29
47,xyy Syndrome 53 25 59
47, Xyy Syndrome 53 72
Xyy Karyotype 53 25
Yy Syndrome 53 25
Y Disomy 53 59
Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome 72
Jacob's Syndrome 25
Jacobs Syndrome 53
Disomy Y 53
Double Y 53

Characteristics:

Orphanet epidemiological data:

59
47,xyy syndrome
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:



External Ids:

MESH via Orphanet 45 C535317 D014997
ICD10 via Orphanet 34 Q98.5
UMLS via Orphanet 73 C0043379 C3266843
Orphanet 59 ORPHA8
UMLS 72 C1859690 C3266843

Summaries for 47,xyy

Genetics Home Reference : 25 47,XYY syndrome is characterized by an extra copy of the Y chromosome in each of a male's cells. Although many males with this condition are taller than average, the chromosomal change sometimes causes no unusual physical features. Most males with 47,XYY syndrome have normal production of the male sex hormone testosterone and normal sexual development, and they are usually able to father children. 47,XYY syndrome is associated with an increased risk of learning disabilities and delayed development of speech and language skills. Affected boys can have delayed development of motor skills (such as sitting and walking) or weak muscle tone (hypotonia). Other signs and symptoms of this condition include hand tremors or other involuntary movements (motor tics), seizures, and asthma. Males with 47,XYY syndrome have an increased risk of behavioral, social, and emotional difficulties compared with their unaffected peers. These problems include attention-deficit/hyperactivity disorder (ADHD); depression; anxiety; and autism spectrum disorder, which is a group of developmental conditions that affect communication and social interaction. Physical features related to 47,XYY syndrome can include increased belly fat, a large head (macrocephaly), unusually large teeth (macrodontia), flat feet (pes planus), fifth fingers that curve inward (clinodactyly), widely spaced eyes (ocular hypertelorism), and abnormal side-to-side curvature of the spine (scoliosis). These characteristics vary widely among affected boys and men.

MalaCards based summary : 47,xyy, also known as xyy syndrome, is related to turner syndrome and camptodactyly-arthropathy-coxa vara-pericarditis syndrome. An important gene associated with 47,xyy is IGFBP3 (Insulin Like Growth Factor Binding Protein 3). The drugs Metformin and Entecavir have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and lung, and related phenotypes are malar flattening and low-set ears

NIH Rare Diseases : 53 47, XYY syndrome is a syndrome (group of signs and symptoms) that affects males. For some males with this syndrome, signs and symptoms are barely noticeable. For others, signs and symptoms may include learning disabilities, speech delay, low muscle tone (hypotonia), and being taller than expected. 47, XYY syndrome is caused by having an extra copy of the Y chromosome in every cell of the body. The syndrome is usually not inherited. Diagnosis can be made based on prenatal tests, or it may occur during childhood or adulthood if a male has signs or symptoms of the disease. Management may include special education as well as intervention or therapies for developmental delays.

Wikipedia : 75 XYY syndrome is a genetic condition in which a male has an extra Y chromosome. Symptoms are usually few.... more...

Related Diseases for 47,xyy

Diseases related to 47,xyy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 127)
# Related Disease Score Top Affiliating Genes
1 turner syndrome 29.0 SRY IGFBP3
2 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 11.6
3 creutzfeldt-jakob disease 11.2
4 47, xxy 10.6
5 azoospermia 10.3
6 tooth size 10.3
7 infertility 10.3
8 autism 10.2
9 autism spectrum disorder 10.2
10 hypogonadotropic hypogonadism 10.2
11 male infertility 10.2
12 hypogonadism 10.2
13 hypogonadotropism 10.2
14 hair whorl 10.1
15 attention deficit-hyperactivity disorder 10.1
16 hypertelorism 10.1
17 down syndrome 10.1
18 cryptorchidism, unilateral or bilateral 10.1
19 oligospermia 10.1
20 gonadal dysgenesis 10.1
21 learning disability 10.1
22 hypotonia 10.1
23 tremor 10.1
24 chromosomal triplication 10.1
25 radioulnar synostosis 10.0
26 synostosis 10.0
27 microcephaly 10.0
28 congenital radioulnar synostosis 10.0
29 lipoid congenital adrenal hyperplasia 10.0
30 brachydactyly 10.0
31 oligohydramnios 10.0
32 agammaglobulinemia 10.0
33 tic disorder 10.0
34 olfactory neuroblastoma 10.0
35 pulmonary embolism 10.0
36 amniotic band syndrome 10.0
37 neurofibromatosis, type ii 10.0
38 elastosis perforans serpiginosa 10.0
39 nondisjunction 10.0
40 noonan syndrome 1 10.0
41 schizophrenia 10.0
42 chromosome 2q35 duplication syndrome 10.0
43 syndactyly, type iii 10.0
44 hypogonadism, male 10.0
45 pseudovaginal perineoscrotal hypospadias 10.0
46 taurodontism 10.0
47 testes, rudimentary 10.0
48 46,xx sex reversal 1 10.0
49 pituitary adenoma, prolactin-secreting 10.0
50 leukemia, acute myeloid 10.0

Graphical network of the top 20 diseases related to 47,xyy:



Diseases related to 47,xyy

Symptoms & Phenotypes for 47,xyy

Human phenotypes related to 47,xyy:

59 32 (show all 34)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 malar flattening 59 32 hallmark (90%) Very frequent (99-80%) HP:0000272
2 low-set ears 59 32 hallmark (90%) Very frequent (99-80%) HP:0000369
3 delayed speech and language development 59 32 hallmark (90%) Very frequent (99-80%) HP:0000750
4 motor delay 59 32 hallmark (90%) Very frequent (99-80%) HP:0001270
5 tall stature 59 32 hallmark (90%) Very frequent (99-80%) HP:0000098
6 macrocephaly 59 32 frequent (33%) Frequent (79-30%) HP:0000256
7 hypertelorism 59 32 frequent (33%) Frequent (79-30%) HP:0000316
8 intellectual disability 59 32 frequent (33%) Frequent (79-30%) HP:0001249
9 neonatal hypotonia 59 32 frequent (33%) Frequent (79-30%) HP:0001319
10 attention deficit hyperactivity disorder 59 32 frequent (33%) Frequent (79-30%) HP:0007018
11 specific learning disability 59 32 frequent (33%) Frequent (79-30%) HP:0001328
12 impaired social interactions 59 32 frequent (33%) Frequent (79-30%) HP:0000735
13 asthma 59 32 frequent (33%) Frequent (79-30%) HP:0002099
14 congenital stationary night blindness 59 32 frequent (33%) Frequent (79-30%) HP:0007642
15 finger clinodactyly 59 32 frequent (33%) Frequent (79-30%) HP:0040019
16 impulsivity 59 32 frequent (33%) Frequent (79-30%) HP:0100710
17 hydrocephalus 59 32 occasional (7.5%) Occasional (29-5%) HP:0000238
18 seizures 59 32 occasional (7.5%) Occasional (29-5%) HP:0001250
19 macroorchidism 59 32 occasional (7.5%) Occasional (29-5%) HP:0000053
20 cryptorchidism 59 32 occasional (7.5%) Occasional (29-5%) HP:0000028
21 increased circulating gonadotropin level 59 32 occasional (7.5%) Occasional (29-5%) HP:0000837
22 hypospadias 59 32 occasional (7.5%) Occasional (29-5%) HP:0000047
23 micropenis 59 32 occasional (7.5%) Occasional (29-5%) HP:0000054
24 azoospermia 59 32 occasional (7.5%) Occasional (29-5%) HP:0000027
25 oligospermia 59 32 occasional (7.5%) Occasional (29-5%) HP:0000798
26 male infertility 59 32 occasional (7.5%) Occasional (29-5%) HP:0003251
27 dysgenesis of the cerebellar vermis 59 32 occasional (7.5%) Occasional (29-5%) HP:0002195
28 abnormality of brainstem morphology 59 32 occasional (7.5%) Occasional (29-5%) HP:0002363
29 cerebellar dysplasia 59 32 occasional (7.5%) Occasional (29-5%) HP:0007033
30 increased serum testosterone level 59 32 occasional (7.5%) Occasional (29-5%) HP:0030088
31 varicocele 59 32 occasional (7.5%) Occasional (29-5%) HP:0012871
32 behavioral abnormality 59 Frequent (79-30%)
33 hyperactivity 59 Frequent (79-30%)
34 autistic behavior 59 Occasional (29-5%)

GenomeRNAi Phenotypes related to 47,xyy according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 8.62 IGFBP3 SRY

Drugs & Therapeutics for 47,xyy

Drugs for 47,xyy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 815)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 4091 14219
2
Entecavir Approved, Investigational Phase 4 142217-69-4 153941
3
Bivalirudin Approved, Investigational Phase 4 128270-60-0 16129704
4
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
5
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610
6
Tranexamic Acid Approved Phase 4 1197-18-8 5526
7
Gliclazide Approved Phase 4 21187-98-4 3475
8
Glimepiride Approved Phase 4 93479-97-1 3476
9
Glyburide Approved Phase 4 10238-21-8 3488
10
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
11
Ciclesonide Approved, Investigational Phase 4 126544-47-6, 141845-82-1 444033
12
Insulin glargine Approved Phase 4 160337-95-1
13
Tinidazole Approved, Investigational Phase 4 19387-91-8 5479
14
Rabeprazole Approved, Investigational Phase 4 117976-89-3 5029
15
Histamine Approved, Investigational Phase 4 51-45-6 774
16
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
17
Modafinil Approved, Investigational Phase 4 68693-11-8 4236
18
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
19
Abciximab Approved Phase 4 143653-53-6
20
Lixisenatide Approved Phase 4 320367-13-3
21
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
22
Haloperidol Approved Phase 4 52-86-8 3559
23
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
24
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
25
Ribavirin Approved Phase 4 36791-04-5 37542
26
Morphine Approved, Investigational Phase 4 57-27-2 5288826
27
Peginterferon alfa-2a Approved, Investigational Phase 4 198153-51-4 5360545
28
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
29
Remifentanil Approved Phase 4 132875-61-7 60815
30
Nystatin Approved, Vet_approved Phase 4 1400-61-9 11953884
31
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
32
Emtricitabine Approved, Investigational Phase 4 143491-57-0 60877
33
Ethanol Approved Phase 4 64-17-5 702
34
Adenosine Approved, Investigational Phase 4 58-61-7 60961
35
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
36
Loratadine Approved, Investigational Phase 4 79794-75-5 3957
37
Ondansetron Approved Phase 4 99614-02-5 4595
38
Timolol Approved Phase 4 26839-75-8 33624 5478
39
Travoprost Approved Phase 4 157283-68-6 5282226
40
Latanoprost Approved, Investigational Phase 4 130209-82-4 5282380 5311221
41
Dorzolamide Approved Phase 4 120279-96-1 3154 5284549
42
Brinzolamide Approved Phase 4 138890-62-7 68844
43
Bimatoprost Approved, Investigational Phase 4 155206-00-1 5311027
44
Norepinephrine Approved Phase 4 51-41-2 439260
45
Eplerenone Approved Phase 4 107724-20-9 150310 443872
46
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
47
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
48
Meperidine Approved Phase 4 57-42-1 4058
49
Bupropion Approved Phase 4 34841-39-9, 34911-55-2 444
50
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456

Interventional clinical trials:

(show top 50) (show all 999)
# Name Status NCT ID Phase Drugs
1 Clinical Trial Program of a Medical Instrument Product Unknown status NCT01157455 Phase 4 Aspirin;Clopidogrel;Heparin or Bivalirudin
2 Randomized Phase IV Trial to Compare Cetuximab With Concomitant Radiation Therapy With Concomitant Mitomycin-C and 5-Fluorouracil With Radiation Therapy for Locally Advanced Squamous Cell Carcinomas of the Head and Neck Unknown status NCT02015650 Phase 4 Cetuximab;Mitomycin-C/ 5-Fluorouracil
3 Cross-reactivity and Tolerability of Ertapenem in Patients With IgE-mediated Allergy to Beta-lactams Unknown status NCT01159379 Phase 4 ertapenem
4 Phase IV Study of the Efficacy of Entecavir in Patients With Chronic Hepatitis B Virus Infection and Persistently Normal Alanine Aminotransferase Unknown status NCT01833611 Phase 4 Entecavir;placebo
5 Minimization of Bleeding Complications Through Utilization of Perioperative Tranexamic Acid in Breast Surgery: A Randomized Double-blinded Placebo-controlled Trial Unknown status NCT02615366 Phase 4 Tranexamic Acid;Placebo
6 A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE SUPPLEMENTATION WITH KIOLIC® IN PATIENTS WITH DIAGNOSIS OF METABOLIC SYNDROME TO IMPROVE ENDOTHELIAL FUNCTION AND INFLAMMATORY STATE. "KYMES" Unknown status NCT01168700 Phase 4 aged garlic extract;Placebo
7 Effects on Incidence of Cardiovascular Events of the Addition of Pioglitazone as Compared With a Sulphonylurea in Type 2 Diabetic Patients Inadequately Controlled With Metformin. Unknown status NCT00700856 Phase 4 add-on pioglitazone;add-on sulphonylurea
8 Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women With PCOS Completed NCT03644212 Phase 4 Vitamin D3
9 Phase 4 Cost-effectiveness Study of Beclomethasone Versus Ciclesonide as Controller Medications in Pediatric Asthma in a Hospital in Bogotá Completed NCT01333800 Phase 4 Beclomethasone;Ciclesonide
10 Modified Non-clarithromycin Triple Therapy in Eradicating Helicobacter Pylori Completed NCT02776371 Phase 4 Modified non-clarithromycin triple therapy;Sequential therapy
11 A Phase IV Open, Randomized, Controlled Study to Evaluate the Safety and Immunogenicity of a Pediatric Presentation (0.25 ml) of the Virosomal Hepatitis A Virus (HAV) Vaccine HAVpur in Healthy Young Children Aged Between and Including 18 Months to 47 Months, Using a 0/6 Month Immunization Schedule Completed NCT01349829 Phase 4
12 Reveal® XT Performance Trial Completed NCT00680927 Phase 4
13 Anti-inflammatory Effects of Intracoronary and Intravenous Abciximab Administration During Primary Percutaneous Coronary Intervention.(Molecole di Adesione Nella Sindrome Coronarica Acuta Completed NCT01757457 Phase 4 Intracoronary administration of an abciximab bolus during primary PCI;Intravenous administration of an abciximab bolus during primary PCI
14 A Randomized, Multicenter, Open-Label, Parallel-Group, 28 Days Phase IV Study Comparing The Postprandial Plasma Glucose Profile of Lixisenatide With That of Sitagliptin Add-On to Insulin Glargine in Type 2 Diabetes Mellitus Completed NCT02200991 Phase 4 LIXISENATIDE AVE0010;Sitagliptin;Insulin glargine HOE901
15 Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol IM Injection for Treatment of Acute Psychotic Agitation in Schizophrenia Completed NCT00859872 Phase 4 risperidone oral solution;haloperidol
16 Respiratory Muscle Stretching in Patients With Chronic Obstructive Pulmonary Disease Submitted a Pulmonary Rehabilitation Program Completed NCT00935181 Phase 4
17 A Feasibility Study: Understanding and Altering Pain Expectations in Subjects With Osteoarthritis of the Knee or Hip Completed NCT02155257 Phase 4 Modafinil;Gabapentin;Placebo
18 Chronic Obstructive Pulmonary Disease and Weaning From Mechanical Ventilation in Difficult to Wean Patients; Randomized Prospective Study Completed NCT00355732 Phase 4
19 Target-controlled Infusion of Propofol and Remifentanil During General Anaesthesia Guided by Entropy of the Electroencephalogram: Comparison Between Manual Perfusion and Automated Perfusion Completed NCT00391885 Phase 4
20 Oral Nystatin Prophylaxis to Prevent Systemic Fungal Infection in Very Low Birth Weight Preterm Infants: a Randomized Controlled Trial Completed NCT03390374 Phase 4 Nystatin Oral
21 The Effect of Prior Short Course Combination Antiretroviral Therapy Administered for the Prevention of Mother-to-Child Transmission (pMTCT) of HIV-1 on Subsequent Treatment Efficacy in Treatment-"Nearly Naive" Participants Completed NCT00442962 Phase 4 Efavirenz;Emtricitabine/Tenofovir disoproxil fumarate
22 A New Strategy Regarding Discontinuation of Dual Antiplatelet; Real Safety and Efficacy of a 3-month Dual Antiplatelet Therapy Following Zotarolimus-eluting Stents Implantation (RESET Trial) Completed NCT01145079 Phase 4
23 Prospective, Randomized Clinical Trial,to Compare Standard Trabeculectomy to the Ex-PRESS Mini Glaucoma Shunt Implantation Under a Scleral Flap in Eyes With Open-Angle Glaucoma Completed NCT00698438 Phase 4
24 Prospective Randomized Trial to Evaluate the Efficacy of Donor Preconditioning With Dopamine on Initial Graft Function After Kidney Transplantation Completed NCT00115115 Phase 4 Dopamine infusion to brain dead organ donors
25 The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment Completed NCT03121521 Phase 4 Melatonin 10 mg;Placebo
26 ADenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination: the ADVICE Trial Completed NCT01058980 Phase 4
27 A Randomized Trial Comparing Daily Atropine Versus Weekend Atropine Completed NCT00094614 Phase 4 Atropine
28 Crystalloid Coload Combined With Variable Rate Phenylephrine Infusion for Prevention of Hypotension During Spinal Anesthesia for Elective Cesarean Delivery vs Crystalloid Coload Alone Completed NCT01378325 Phase 4 Phenylephrine;saline
29 A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study Evaluating the Pharmacodynamic Effect of a 6-week Treatment With Triamcinolone Acetonide Aqueous Nasal Spray 110 μg and 220 μg Once Daily on Basal Hypothalamic-Pituitary-Adrenal (HPA) Axis Function in Children [>=2 to < 12 Years of Age] With Allergic Rhinitis (AR). Completed NCT01154153 Phase 4 Placebo nasal spray;Triamcinolone acetonide aqueous (TAA-AQ) nasal spray (NASACORT AQ);Placebo nasal spray;Claritin® Syrup
30 Effect of Aspirin Intake on Awakening Versus at Bedtime on Circadian Rhythm of Platelet Reactivity in Healthy Subjects Completed NCT01900639 Phase 4
31 Choroidal Thickness and Its Correlations With Ocular Parameters in Cases With Primary Open-angle Glaucoma Completed NCT03966560 Phase 4 Brimonidine Tartrate;Dorzolamide (as Dorzolamide Hydrochloride) 20 Mg/mL and Timolol (as Timolol Maleate) 5 Mg/mL Eye Drops;Brinzolamide/Timolol 10 MG/1 ML-5 MG/1 ML Ophthalmic Suspension;Travoprost and Timolol;Bimatoprost and Timolol;Latanoprost
32 Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules Completed NCT02765763 Phase 4 2-Minute Reveal Masque;24/7 Barrier Repair Cream;8-in-1 BioSerum;Null Formula 2-Minute Reveal Masque;Null Formula 24/7 Barrier Repair Cream;Null Formula 8-in-1 BioSerum
33 Comparison of the Effect of Fluoride Remineralizer Gel and Foam: a Randomized Clinical Trial Completed NCT02490592 Phase 4
34 Patient-controlled Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis Completed NCT02669004 Phase 4 Intermittent bolus epidural morphine;continuous epidural morphine
35 Effectiveness and Safety of Inactivated EV71 Vaccine (Human Diploid Cell) in 6-71 Months Children: an Open-label Controlled Phase Ⅳ Clinical Study Completed NCT03001986 Phase 4
36 Impact of Dexmedetomidine on the Incidence of Postoperative Delirium in Patients After Cardiac Surgery: a Randomized, Double-blinded, and Placebo-controlled Clinical Trial Completed NCT02267538 Phase 4 dexmedetomidine hydrochloride for injection;0.9% sodium chloride for injection
37 Effects of Anemia Correction on Vascular Function, Endothelial Cell Markers and Monocyte Apoptosis in Renal Transplant Recipients Completed NCT00204334 Phase 4 darbopoeitin
38 Prospective, Randomized Clinical Trial of a Silver Eluting Dressing System for Prevention of Lower Extremity Revascularization Wound Complications Completed NCT01229358 Phase 4
39 Nasally Inhaled Isopropyl Alcohol Versus Oral Ondansetron for the Treatment of Nausea in the Emergency Department: A Double-Blind Randomized Controlled Trial Completed NCT02760069 Phase 4 Inhaled isopropyl alcohol;Oral ondansetron;Inhaled normal saline;Oral placebo
40 Randomized Trial of 24 or 48 Weeks of Peginterferon Alfa-2a Plus Ribavirin for Chronic Hepatitis C Virus Genotype 1-infected Patients in Taiwan Completed NCT00495131 Phase 4 Pegylated interferon alfa-2a plus ribavirin;Pegylated interferon alfa-2a plus ribavirin
41 Study of Methylphenidate to Treat Gait Disorders And Attention Deficit In Parkinson's Disease: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentric Trial Completed NCT00914095 Phase 4 methylphenidate;placebo
42 Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP Completed NCT01404689 Phase 4 Dexmedetomidine
43 Effects of Eplerenone on Left Ventricular Hypertrophy in Patients With Resistant Hypertension and Obstructive Sleep Apnoea Completed NCT03186742 Phase 4 Eplerenone 50 mg Tab
44 Nicotine Replacement Therapy Added to Cognitive Behavioral Therapy for Smoking Cessation in Patients With Major Mental Illness Completed NCT00320723 Phase 4 bupropion, transdermal nicotine patch
45 A Randomized Trial of Deep Neuromuscular Blockade Reversed With Sugammadex Versus Moderate Neuromuscular Block Reversed With Neostigmine, on Postoperative Quality of Recovery Completed NCT03034577 Phase 4 Sugammadex;Neostigmine
46 Phase 4 Study of Primary Use of the Vacuum Assisted Laparostomy in Treatment of Severe Peritonitis Completed NCT01531543 Phase 4
47 Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) : Pattern Electroretinography Study Completed NCT03046693 Phase 4 Group A Citicoline 1000 mg oral tablet;Group B placebo oral tablet
48 Multi-Port vs. Single-port Cholecystectomy Completed NCT01104727 Phase 4
49 An Open-label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Ixazomib in Combination With Lenalidomide and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma Initially Treated With an Injection of Proteasome Inhibitor-Based Therapy Recruiting NCT03416374 Phase 4 Ixazomib;Bortezomib;Carfilzomib;Lenalidomide;Dexamethasone
50 Effects of Nitroglycerin Versus Labetalol on Tissue Perfusion During Deliberate Hypotension for Sinus Endoscopic Surgery. Recruiting NCT03809065 Phase 4 Nitroglycerin;Labetalol

Search NIH Clinical Center for 47,xyy

Genetic Tests for 47,xyy

Genetic tests related to 47,xyy:

# Genetic test Affiliating Genes
1 Double Y Syndrome 29

Anatomical Context for 47,xyy

MalaCards organs/tissues related to 47,xyy:

41
Breast, Testes, Lung, Liver, Bone, Heart, Brain

Publications for 47,xyy

Articles related to 47,xyy:

(show top 50) (show all 30000)
# Title Authors PMID Year
1
Clinical aspects of infertile 47,XYY patients: a retrospective study. 38 6
28715980 2019
2
Oral, physical, and behavioral aspects of patient with chromosome 47, XYY syndrome. 38 6
26381641 2015
3
Positive effects of early androgen therapy on the behavioral phenotype of boys with 47,XXY. 38 6
25939399 2015
4
High-rate activated sludge systems combined with dissolved air flotation enable effective organics removal and recovery. 38
31357043 2019
5
Identification of the antiglycative components of Hong Dou Shan (Taxus chinensis) leaf tea. 38
31253329 2019
6
Characteristics of CO₂ Capture by Tetraethylenepentamine Modified Mesoporous Silica Morphology. 38
31026950 2019
7
Effect of light on the transformation of BDE-47 by living and autoclaved cultures of Microcystis flos-aquae and Chlorella vulgaris. 38
31170584 2019
8
Cellular metabolomics reveals glutamate and pyrimidine metabolism pathway alterations induced by BDE-47 in human neuroblastoma SK-N-SH cells. 38
31302334 2019
9
Gender disparity in ICU staffing in Argentina. 38
31174174 2019
10
Insight into the tolerance, biochemical and antioxidative response in three moss species on exposure to BDE-47 and BDE-209. 38
31228820 2019
11
Perigestational low-dose BDE-47 exposure alters maternal serum metabolome and results in sex-specific weight gain in adult offspring. 38
31173955 2019
12
Common bean seeds from plants subjected to severe drought, restricted- and full-irrigation regimes show differential phytochemical fingerprint. 38
31126476 2019
13
High voltage electric discharges treatment for high molecular weight hemicelluloses extraction from spruce. 38
31320084 2019
14
Pathways and biomarkers of marbling and carcass fat deposition in bovine revealed by a combination of gel-based and gel-free proteomic analyses. 38
31158601 2019
15
Evidence for the role of inhibition in numerical comparison: A negative priming study in 7- to 8-year-olds and adults. 38
31254911 2019
16
Urethro-vaginal reflux during micturition: An underestimated cause of urinary incontinence in adult women. 38
31436352 2019
17
Diabetes as a risk factor for heart failure in women and men: a systematic review and meta-analysis of 47 cohorts including 12 million individuals. 38
31317230 2019
18
Thrombotic Aneurysm of Posterior Inferior Cerebellar Artery. 38
31077899 2019
19
Diffuse Infiltration of Multiple Myeloma With Initial Manifestation of Cavernous Sinus Syndrome Unveiled by 18F-FDG PET/CT. 38
31306198 2019
20
Effect of Direct Vertebral Rotation in Single Thoracic Adolescent Idiopathic Scoliosis: Better 3-Dimensional Deformity Correction. 38
31150860 2019
21
Degradation of 2,2',4,4'-tetrabromodiphenyl ether by Pycnoporus sanguineus in the presence of copper ions. 38
31221376 2019
22
Correction: Substituents drive ligand rearrangements, giving dinuclear rather than mononuclear complexes, and tune CoII/III redox potential. 38
31396603 2019
23
Incidence and outcome of invasive fungal disease after front-line intensive chemotherapy in patients with acute myeloid leukemia: impact of antifungal prophylaxis. 38
31240471 2019
24
Speech Perception Outcomes in Transcutaneous Versus Percutaneous Bone Conduction Stimulation in Individuals With Single-sided Deafness. 38
31356484 2019
25
Predictors and Outcomes of Persistent Tricuspid Regurgitation After Transcatheter Aortic Valve Implantation. 38
31280838 2019
26
Randomised study comparing heart rate measurement in newly born infants using a monitor incorporating electrocardiogram and pulse oximeter versus pulse oximeter alone. 38
30425114 2019
27
Reduction of plasma angiopoietin-like 2 after cardiac surgery is related to tissue inflammation and senescence status of patients. 38
30745045 2019
28
Pilot Study: Neurocognitive Disorders and Colonoscopy in Older Adults. 38
31425226 2019
29
Reporting medical device safety incidents to regulatory authorities: An analysis and classification of technology-induced errors. 38
28747134 2019
30
Dual-phase CT angiography for presurgical planning in patients with vessel-depleted neck. 38
31017350 2019
31
Tubercular posterior scleritis: A case report and review of literature. 38
31332144 2019
32
Is it possible to extrapolate the rates of resistance of Escherichia coli from asymptomatic bacteriuria in pregnant women to those of E. coli in uncomplicated community-acquired UTI? 38
31328907 2019
33
Radiochemical separation of reactor produced Sc-47 from natural calcium target using Poly(acrylamide-acrylic acid)/multi-walled carbon nanotubes composite. 38
31128498 2019
34
Serious Cutaneous Toxicities with Immune Checkpoint Inhibitors in the U.S. Food and Drug Administration Adverse Event Reporting System. 38
31387950 2019
35
Direct-Acting Antivirals in Hepatitis C Virus-Associated Diffuse Large B-cell Lymphomas. 38
30552159 2019
36
Last crusade against HCV: Direct-acting antiviral treatment for marginalized populations. 38
31411788 2019
37
Operative Hysteroscopy Intravascular Absorption Syndrome Causing Hyponatremia with Associated Cerebral and Pulmonary Edema. 38
31404167 2019
38
Exploring associations between water, sanitation, and anemia through 47 nationally representative demographic and health surveys. 38
31232465 2019
39
Clinical Experience and Management of Squat-Induced Lower Extremity Arterial Ischemia. 38
31382002 2019
40
Giant cell reparative granuloma of the scapula: report of a case and literature review. 38
30607456 2019
41
The Impact of Infection and Elevated INR in LVAD-Associated Intracranial Hemorrhage: A Case-Crossover Study. 38
30312211 2019
42
Reinterventions after freestyle stentless aortic valve replacement: an assessment of procedural risks. 38
31424504 2019
43
Comparison of the International Classification of High-resolution Computed Tomography for occupational and environmental respiratory diseases with the International Labor Organization International Classification of Radiographs of Pneumoconiosis. 38
30344228 2019
44
Limiting factors for autologous transplantation among transplant-eligible multiple myeloma patients: Lesson from a Tertiary Cancer Centre in rural India. 38
31200146 2019
45
Three-stage anaerobic co-digestion of food waste and waste activated sludge: Identifying bacterial and methanogenic archaeal communities and their correlations with performance parameters. 38
31004947 2019
46
Effectiveness of Sequential Compression Devices in Prevention of Venous Thromboembolism in Medically Ill Hospitalized Patients: A Retrospective Cohort Study 38
31042860 2019
47
Shedding light on the FDA's 510(k) approvals process: low-level laser therapy devices used in the treatment of androgenetic alopecia. 38
30252550 2019
48
Pregnancy-associated breast cancer: A review of 47 women. 38
31404824 2019
49
Behçet's disease presentations and care outcomes in a tertiary hospital in south-western Saudi Arabia. 38
31099192 2019
50
Aberrantly elevated Bmi1 promotes cervical cancer tumorigenicity and tumor sphere formation via enhanced transcriptional regulation of Sox2 genes. 38
31173263 2019

Variations for 47,xyy

Expression for 47,xyy

Search GEO for disease gene expression data for 47,xyy.

Pathways for 47,xyy

GO Terms for 47,xyy

Sources for 47,xyy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....