MCID: 6PH001
MIFTS: 19

6-Phosphogluconate Dehydrogenase Deficiency

Categories: Blood diseases, Rare diseases

Aliases & Classifications for 6-Phosphogluconate Dehydrogenase Deficiency

MalaCards integrated aliases for 6-Phosphogluconate Dehydrogenase Deficiency:

Name: 6-Phosphogluconate Dehydrogenase Deficiency 59
6-Phosphogluconate Dehydrogenase 13

Classifications:



External Ids:

Orphanet 59 ORPHA99135
ICD10 via Orphanet 34 D55.1

Summaries for 6-Phosphogluconate Dehydrogenase Deficiency

MalaCards based summary : 6-Phosphogluconate Dehydrogenase Deficiency, also known as 6-phosphogluconate dehydrogenase, is related to thyroiditis and aging. An important gene associated with 6-Phosphogluconate Dehydrogenase Deficiency is G6PD (Glucose-6-Phosphate Dehydrogenase), and among its related pathways/superpathways are Glycosaminoglycan metabolism and Glucose / Energy Metabolism.

Wikipedia : 76 6-Phosphogluconate dehydrogenase deficiency (6PGD deficiency), or partial deficiency, is an autosomal... more...

Related Diseases for 6-Phosphogluconate Dehydrogenase Deficiency

Diseases related to 6-Phosphogluconate Dehydrogenase Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 15)
# Related Disease Score Top Affiliating Genes
1 thyroiditis 10.0
2 aging 9.9
3 leukemia, acute myeloid 9.9
4 hemolytic anemia 9.9
5 leukemia 9.9
6 sleeping sickness 9.9
7 trypanosomiasis 9.9
8 thyroid cancer 9.9
9 cervicitis 9.9
10 myeloid leukemia 9.9
11 cervix uteri carcinoma in situ 9.9
12 anaplastic thyroid cancer 9.9
13 cervical intraepithelial neoplasia 9.9
14 trypanosomiasis, human east-african 9.9
15 glucosephosphate dehydrogenase deficiency 9.0 G6PD PGD

Graphical network of the top 20 diseases related to 6-Phosphogluconate Dehydrogenase Deficiency:



Diseases related to 6-Phosphogluconate Dehydrogenase Deficiency

Symptoms & Phenotypes for 6-Phosphogluconate Dehydrogenase Deficiency

Drugs & Therapeutics for 6-Phosphogluconate Dehydrogenase Deficiency

Search Clinical Trials , NIH Clinical Center for 6-Phosphogluconate Dehydrogenase Deficiency

Genetic Tests for 6-Phosphogluconate Dehydrogenase Deficiency

Anatomical Context for 6-Phosphogluconate Dehydrogenase Deficiency

Publications for 6-Phosphogluconate Dehydrogenase Deficiency

Articles related to 6-Phosphogluconate Dehydrogenase Deficiency:

# Title Authors Year
1
6-Phosphogluconate dehydrogenase deficiency in an Italian family. ( 11233775 )
2001
2
A NEW INHERITED ENZYMATIC DEFICIENCY OF HUMAN ERYTHROCYTES: 6-PHOSPHOGLUCONATE DEHYDROGENASE DEFICIENCY. ( 14250427 )
1964

Variations for 6-Phosphogluconate Dehydrogenase Deficiency

Expression for 6-Phosphogluconate Dehydrogenase Deficiency

Search GEO for disease gene expression data for 6-Phosphogluconate Dehydrogenase Deficiency.

Pathways for 6-Phosphogluconate Dehydrogenase Deficiency

GO Terms for 6-Phosphogluconate Dehydrogenase Deficiency

Biological processes related to 6-Phosphogluconate Dehydrogenase Deficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.26 G6PD PGD
2 pentose-phosphate shunt GO:0006098 9.16 G6PD PGD
3 pentose-phosphate shunt, oxidative branch GO:0009051 8.96 G6PD PGD
4 pentose biosynthetic process GO:0019322 8.62 G6PD PGD

Molecular functions related to 6-Phosphogluconate Dehydrogenase Deficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 8.62 G6PD PGD

Sources for 6-Phosphogluconate Dehydrogenase Deficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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