MCID: 8P1002
MIFTS: 40

8p11 Myeloproliferative Syndrome

Categories: Immune diseases, Cancer diseases, Rare diseases, Blood diseases

Aliases & Classifications for 8p11 Myeloproliferative Syndrome

MalaCards integrated aliases for 8p11 Myeloproliferative Syndrome:

Name: 8p11 Myeloproliferative Syndrome 25
Myeloid and Lymphoid Neoplasms with Fgfr1 Abnormalities 25
Myeloid and Lymphoid Neoplasms with Fgfr1 Rearrangement 73
Chromosome 8p11 Myeloproliferative Syndrome 73
8p11 Stem Cell Leukemia/lymphoma Syndrome 25
Stem Cell Leukemia/lymphoma 25
8p11 Stem Cell Syndrome 25

Classifications:



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Summaries for 8p11 Myeloproliferative Syndrome

Genetics Home Reference : 25 8p11 myeloproliferative syndrome is a blood cancer that involves different types of blood cells. Blood cells are divided into several groups (lineages) based on the type of early cell from which they are descended. Two of these lineages are myeloid cells and lymphoid cells. Individuals with 8p11 myeloproliferative syndrome can develop both myeloid cell cancer and lymphoid cell cancer.

MalaCards based summary : 8p11 Myeloproliferative Syndrome, also known as myeloid and lymphoid neoplasms with fgfr1 abnormalities, is related to chromosome 8p11 myeloproliferative syndrome and acute leukemia. An important gene associated with 8p11 Myeloproliferative Syndrome is FGFR1 (Fibroblast Growth Factor Receptor 1), and among its related pathways/superpathways are HIV Life Cycle and Cytokine Signaling in Immune system. Affiliated tissues include myeloid, b cells and bone, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for 8p11 Myeloproliferative Syndrome

Diseases in the 8p11 Myeloproliferative Syndrome family:

Myeloproliferative Syndrome, Transient Myeloproliferative Disease, Autosomal Recessive

Diseases related to 8p11 Myeloproliferative Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 chromosome 8p11 myeloproliferative syndrome 35.0 FGFR1 SCLL
2 acute leukemia 30.1 FLT3 KIT RUNX1
3 leukemia, acute lymphoblastic 29.8 BCR FLT3 RUNX1
4 leukemia 29.3 BCR FLT3 KIT RUNX1
5 myeloid leukemia 29.3 BCR FLT3 KIT RUNX1
6 leukemia, acute myeloid 29.0 BCR FLT3 KIT RUNX1 ZMYM2
7 primary hypereosinophilic syndrome 10.7 FGFR1 PDGFRB
8 myeloid and lymphoid neoplasms with eosinophilia and abnormalities of pdgfra, pdgfrb, and fgfr1 10.6 FGFR1 PDGFRB
9 acute myeloblastic leukemia with maturation 10.5 FLT3 KIT
10 desmoid tumor 10.5 KIT PDGFRB
11 hypereosinophilic syndrome, idiopathic 10.4 KIT PDGFRB
12 pulmonary vein stenosis 10.4 KDR KIT
13 systemic mastocytosis 10.3 FGFR1 KIT PDGFRB
14 acute myeloid leukemia with t(8;21)(q22;q22) translocation 10.2 FLT3 KIT RUNX1
15 hypereosinophilic syndrome 10.2 FGFR1 KIT PDGFRB
16 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 10.2 FLT3 KIT RUNX1
17 core binding factor acute myeloid leukemia 10.2 FLT3 KIT RUNX1
18 senile angioma 10.2 KDR KIT
19 fibrosarcoma of bone 10.2 KDR KIT PDGFRB
20 lymphoma 10.1
21 vascular cancer 10.1 KDR KIT PDGFRB
22 pilocytic astrocytoma 10.1 FGFR1 KDR PDGFRB
23 lymphoblastic lymphoma 10.0
24 lymphoblastic leukemia 10.0
25 chronic eosinophilic leukemia 9.9 FGFR1 FLT3 KIT PDGFRB
26 leukemia, acute lymphoblastic 3 9.9 BCR FLT3 RUNX1
27 chronic myelomonocytic leukemia 9.8 FLT3 KIT PDGFRB RUNX1
28 heart sarcoma 9.8 KIT PDGFRB
29 myeloproliferative neoplasm 9.7 BCR FGFR1 KIT PDGFRB
30 juvenile myelomonocytic leukemia 9.7 FLT3 PDGFRB RUNX1
31 renal cell carcinoma, nonpapillary 9.6 FLT3 KDR KIT PDGFRB
32 gastrointestinal stromal tumor 9.6 FLT3 KIT PDGFRB
33 myelodysplastic syndrome 9.5 FLT3 KIT PDGFRB RUNX1
34 leukemia, chronic myeloid 9.0 BCR FGFR1 FLT3 KIT PDGFRB RUNX1
35 hematologic cancer 8.5 BCR FGFR1 FLT3 KDR KIT PDGFRB
36 bone marrow cancer 7.6 BCR FGFR1 FGFR1OP FLT3 KDR KIT

Graphical network of the top 20 diseases related to 8p11 Myeloproliferative Syndrome:



Diseases related to 8p11 Myeloproliferative Syndrome

Symptoms & Phenotypes for 8p11 Myeloproliferative Syndrome

GenomeRNAi Phenotypes related to 8p11 Myeloproliferative Syndrome according to GeneCards Suite gene sharing:

26 (show all 40)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00173-A 9.96 FLT3
2 Decreased viability GR00221-A-1 9.96 KIT PDGFRB FGFR1 FLT3 KDR
3 Decreased viability GR00221-A-2 9.96 FGFR1 KDR
4 Decreased viability GR00221-A-3 9.96 KDR PDGFRB
5 Decreased viability GR00221-A-4 9.96 KDR PDGFRB FLT3
6 Decreased viability GR00301-A 9.96 KIT
7 Decreased viability GR00342-S-1 9.96 PDGFRB
8 Decreased viability GR00402-S-2 9.96 KIT PDGFRB FGFR1 FLT3 KDR
9 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.84 BCR
10 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.84 KIT
11 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.84 TPR
12 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.84 BCR
13 Increased shRNA abundance (Z-score > 2) GR00366-A-116 9.84 TPR
14 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.84 TPR
15 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.84 BCR
16 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.84 TRIM24
17 Increased shRNA abundance (Z-score > 2) GR00366-A-124 9.84 BCR
18 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.84 KDR TRIM24
19 Increased shRNA abundance (Z-score > 2) GR00366-A-127 9.84 TRIM24
20 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.84 KIT
21 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.84 KIT
22 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.84 BCR
23 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.84 BCR
24 Increased shRNA abundance (Z-score > 2) GR00366-A-170 9.84 KIT
25 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.84 BCR
26 Increased shRNA abundance (Z-score > 2) GR00366-A-205 9.84 TPR
27 Increased shRNA abundance (Z-score > 2) GR00366-A-215 9.84 BCR
28 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.84 BCR
29 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.84 KIT
30 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.84 KDR
31 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.84 KIT
32 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.84 TRIM24
33 Increased shRNA abundance (Z-score > 2) GR00366-A-83 9.84 BCR
34 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.84 TPR TRIM24 BCR KDR KIT
35 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.84 KIT
36 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.84 KIT
37 Decreased substrate adherent cell growth GR00193-A-1 9.63 KIT
38 Decreased substrate adherent cell growth GR00193-A-2 9.63 KIT
39 Decreased substrate adherent cell growth GR00193-A-4 9.63 FGFR1 FLT3 KDR KIT
40 Decreased human cytomegalovirus (HCMV) strain AD169 replication GR00248-A 9.56 FGFR1 FLT3 KDR PDGFRB

MGI Mouse Phenotypes related to 8p11 Myeloproliferative Syndrome:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.02 BCR FGF1 FGFR1 FGFR1OP FLT3 KDR
2 homeostasis/metabolism MP:0005376 10 NSMAF PDGFRB RUNX1 TRIM24 BCR FGF1
3 integument MP:0010771 9.7 FGFR1 KDR KIT MYO18A NSMAF PDGFRB
4 mortality/aging MP:0010768 9.7 BCR FGFR1 FGFR1OP FLT3 KDR KIT
5 vision/eye MP:0005391 9.17 CNTRL FGFR1 FGFR1OP KDR KIT MYO18A

Drugs & Therapeutics for 8p11 Myeloproliferative Syndrome

Search Clinical Trials , NIH Clinical Center for 8p11 Myeloproliferative Syndrome

Genetic Tests for 8p11 Myeloproliferative Syndrome

Anatomical Context for 8p11 Myeloproliferative Syndrome

MalaCards organs/tissues related to 8p11 Myeloproliferative Syndrome:

41
Myeloid, B Cells, Bone, Bone Marrow

Publications for 8p11 Myeloproliferative Syndrome

Articles related to 8p11 Myeloproliferative Syndrome:

(show all 34)
# Title Authors Year
1
Primary cells in BCR/FGFR1 positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib. ( 28881484 )
2017
2
8p11 Myeloproliferative Syndrome with t(7;8) Translocation Presenting as Acute Myeloid Leukemia: A Case Report and Literature Review. ( 27188774 )
2016
3
Diagnostic application of next-generation sequencing in ZMYM2-FGFR1 8p11 myeloproliferative syndrome: A case report. ( 27415155 )
2016
4
8p11 myeloproliferative syndrome: diagnostic challenges and pitfalls. ( 27569099 )
2016
5
8p11 myeloproliferative syndrome: A case report of this rare clinical entity. ( 25885151 )
2015
6
Screening of Drugs to Treat 8p11 Myeloproliferative Syndrome Using Patient-Derived Induced Pluripotent Stem Cells with Fusion Gene CEP110-FGFR1. ( 25803811 )
2015
7
Functional characterization, localization, and inhibitor sensitivity of the TPR-FGFR1 fusion in 8p11 myeloproliferative syndrome. ( 26391436 )
2015
8
8p11 Myeloproliferative Syndrome with t(1;8)(q25;p11.2): A Case Report and Review of the Literature. ( 25227135 )
2014
9
A case of 8p11 myeloproliferative syndrome with BCR-FGFR1 gene fusion presenting with trilineage acute leukemia/lymphoma, successfully treated by cord blood transplantation. ( 23171834 )
2013
10
Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome. ( 22875613 )
2013
11
Quantitative polymerase chain reaction detection of CEP110-FGFR1 fusion gene in a patient with 8p11 myeloproliferative syndrome. ( 23327291 )
2013
12
A novel t(1;8)(q25;p11.2) translocation associated with 8p11 myeloproliferative syndrome. ( 21848523 )
2012
13
Favorable outcome of allogeneic hematopoietic cell transplantation for 8p11 myeloproliferative syndrome associated with BCR-FGFR1 gene fusion. ( 22106025 )
2012
14
Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome. ( 22619110 )
2012
15
The 8p11 myeloproliferative syndrome owing to rare FGFR1OP2-FGFR1 fusion. ( 21198859 )
2011
16
8p11 Myeloproliferative syndrome with BCR-FGFR1 rearrangement presenting with T-lymphoblastic lymphoma and bone marrow stromal cell proliferation: a case report and review of the literature. ( 21239058 )
2011
17
Translocation t(3;8;9)(p25;p21;q34) in a patient with features of 8p11 myeloproliferative syndrome: a unique case and review of the literature. ( 20541805 )
2010
18
8p11 myeloproliferative syndrome: a review. ( 20226962 )
2010
19
B-cell acute lymphoblastic leukemia as evolution of a 8p11 myeloproliferative syndrome with t(8;22)(p11;q11) and BCR-FGFR1 fusion gene. ( 20594995 )
2010
20
Biphenotypic hematologic malignancy: a case report of the 8p11 myeloproliferative syndrome in a child. ( 20562652 )
2010
21
Complete molecular remission after interferon alpha treatment in a case of 8p11 myeloproliferative syndrome. ( 20650528 )
2010
22
LRRFIP1, a new FGFR1 partner gene associated with 8p11 myeloproliferative syndrome. ( 19369959 )
2009
23
Molecular monitoring of 8p11 myeloproliferative syndrome in an infant. ( 19829149 )
2009
24
The 8p11 myeloproliferative syndrome in a 3-year-old child. ( 17555813 )
2008
25
8p11 myeloproliferative syndrome preceded by t(8;9)(p11;q33), CEP110/FGFR1 fusion transcript: morphologic, molecular, and cytogenetic characterization of myeloid neoplasms associated with eosinophilia and FGFR1 abnormality. ( 18295660 )
2008
26
The 8p11 myeloproliferative syndrome: review of literature and an illustrative case report. ( 18787627 )
2008
27
Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome. ( 17394134 )
2007
28
Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome. ( 17698633 )
2007
29
A biphenotypic transformation of 8p11 myeloproliferative syndrome with CEP1/FGFR1 fusion gene. ( 16879608 )
2006
30
8p11 myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFR1 and TIF1 genes. ( 15609342 )
2005
31
The t(8;17)(p11;q23) in the 8p11 myeloproliferative syndrome fuses MYO18A to FGFR1. ( 15800673 )
2005
32
Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome. ( 15034873 )
2004
33
The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1. ( 11919391 )
2002
34
[The 8p11 myeloproliferative syndrome]. ( 10373756 )
1999

Variations for 8p11 Myeloproliferative Syndrome

Expression for 8p11 Myeloproliferative Syndrome

Search GEO for disease gene expression data for 8p11 Myeloproliferative Syndrome.

Pathways for 8p11 Myeloproliferative Syndrome

Pathways related to 8p11 Myeloproliferative Syndrome according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.47 BCR CNTRL FGF1 FGFR1 FGFR1OP FGFR1OP2
2
Show member pathways
13.2 FGF1 FGFR1 FLT3 KIT PDGFRB TPR
3
Show member pathways
13.16 FGF1 FGFR1 FLT3 KDR KIT PDGFRB
4
Show member pathways
13.11 FGF1 FGFR1 FLT3 KDR KIT PDGFRB
5
Show member pathways
12.9 FGF1 FGFR1 KDR KIT PDGFRB
6
Show member pathways
12.88 FGF1 FGFR1 KDR KIT PDGFRB
7
Show member pathways
12.84 FGF1 FGFR1 FLT3 KDR KIT PDGFRB
8
Show member pathways
12.79 FGFR1 FLT3 KDR KIT PDGFRB
9
Show member pathways
12.72 BCR FGFR1 FLT3 KIT PDGFRB RUNX1
10 12.67 FGF1 FGFR1 FLT3 KDR KIT PDGFRB
11
Show member pathways
12.61 FGF1 FGFR1 FLT3 KDR KIT PDGFRB
12 12.58 BCR FGF1 FGFR1 FLT3 KIT PDGFRB
13
Show member pathways
12.34 FGFR1 KDR PDGFRB TRIM24
14
Show member pathways
12.1 FGFR1 FGFR1OP FGFR1OP2 KDR
15
Show member pathways
11.93 FGFR1 KDR PDGFRB
16 11.89 KDR PDGFRB RUNX1
17 11.87 BCR FGF1 FGFR1 FLT3 KDR KIT
18
Show member pathways
11.81 BCR CNTRL FGF1 FGFR1 FGFR1OP FGFR1OP2
19 11.76 FGF1 FGFR1 KDR PDGFRB
20
Show member pathways
11.69 FGFR1 FLT3 KDR KIT PDGFRB
21 11.59 FGFR1 FLT3 KIT PDGFRB
22
Show member pathways
11.55 BCR KDR KIT PDGFRB
23 11.33 FGF1 FGFR1 KDR PDGFRB
24
Show member pathways
11.23 BCR CNTRL FGF1 FGFR1 FGFR1OP FGFR1OP2

GO Terms for 8p11 Myeloproliferative Syndrome

Cellular components related to 8p11 Myeloproliferative Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.9 BCR CNTRL FGF1 FGFR1 FGFR1OP FGFR1OP2
2 cytoplasm GO:0005737 9.83 BCR CNTRL FGF1 FGFR1 FGFR1OP FGFR1OP2
3 receptor complex GO:0043235 9.02 FGFR1 FLT3 KDR KIT PDGFRB

Biological processes related to 8p11 Myeloproliferative Syndrome according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.98 FGF1 FGFR1 FGFR1OP FLT3 KDR KIT
2 MAPK cascade GO:0000165 9.92 FGF1 FGFR1 KIT PDGFRB
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.91 FGFR1 FLT3 KDR KIT PDGFRB
4 positive regulation of cell migration GO:0030335 9.89 FGF1 FGFR1OP KDR KIT PDGFRB
5 positive regulation of protein kinase B signaling GO:0051897 9.87 FGF1 FGFR1 KIT PDGFRB
6 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.86 FLT3 KDR KIT PDGFRB
7 positive regulation of MAPK cascade GO:0043410 9.85 FGFR1 FLT3 KDR KIT PDGFRB
8 phosphatidylinositol phosphorylation GO:0046854 9.83 FGF1 FGFR1 KIT PDGFRB
9 positive regulation of angiogenesis GO:0045766 9.81 FGF1 KDR RUNX1
10 hemopoiesis GO:0030097 9.77 FLT3 KIT RUNX1
11 negative regulation of signal transduction GO:0009968 9.77 FGFR1 FLT3 KDR KIT PDGFRB
12 positive regulation of kinase activity GO:0033674 9.72 FGFR1 FLT3 KDR KIT PDGFRB
13 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.71 FLT3 KIT PDGFRB
14 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.65 FGFR1 FLT3 KDR KIT PDGFRB
15 embryonic hemopoiesis GO:0035162 9.63 KDR KIT
16 vascular endothelial growth factor signaling pathway GO:0038084 9.61 FLT3 KDR
17 organ induction GO:0001759 9.61 FGF1 FGFR1
18 myeloid progenitor cell differentiation GO:0002318 9.58 FLT3 KIT
19 positive regulation of phospholipase C activity GO:0010863 9.58 FGFR1 KIT PDGFRB
20 positive regulation of MAP kinase activity GO:0043406 9.55 FGF1 FGFR1 FLT3 KIT PDGFRB
21 protein autophosphorylation GO:0046777 9.5 BCR FGFR1 FLT3 KDR KIT PDGFRB
22 peptidyl-tyrosine phosphorylation GO:0018108 9.4 BCR CNTRL FGF1 FGFR1 FGFR1OP FGFR1OP2
23 multicellular organism development GO:0007275 10.14 FGF1 FGFR1 FLT3 KDR KIT PDGFRB
24 cell differentiation GO:0030154 10.1 FGF1 FGFR1 FLT3 KDR KIT PDGFRB
25 phosphorylation GO:0016310 10.05 BCR FGFR1 FLT3 KDR KIT PDGFRB
26 negative regulation of apoptotic process GO:0043066 10.02 FGFR1 FLT3 KDR KIT MYO18A PDGFRB
27 protein phosphorylation GO:0006468 10.02 BCR FGFR1 FLT3 KDR KIT PDGFRB

Molecular functions related to 8p11 Myeloproliferative Syndrome according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 kinase activity GO:0016301 9.97 BCR FGFR1 FLT3 KDR KIT PDGFRB
2 nucleotide binding GO:0000166 9.88 FGFR1 KIT MYO18A PDGFRB
3 transmembrane signaling receptor activity GO:0004888 9.88 FGFR1 FLT3 KDR KIT PDGFRB
4 protein kinase activity GO:0004672 9.88 FGFR1 FLT3 KDR KIT PDGFRB TRIM24
5 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.73 FGF1 FGFR1 KIT PDGFRB
6 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.67 FGF1 FGFR1 KIT PDGFRB
7 MAP kinase kinase kinase activity GO:0004709 9.65 FGFR1 FLT3 KDR KIT PDGFRB
8 growth factor binding GO:0019838 9.62 FLT3 KDR KIT PDGFRB
9 obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity GO:0004716 9.56 KDR KIT
10 mitogen-activated protein kinase kinase binding GO:0031434 9.55 FGFR1 FLT3 KDR KIT PDGFRB
11 vascular endothelial growth factor-activated receptor activity GO:0005021 9.54 FLT3 KDR
12 vascular endothelial growth factor binding GO:0038085 9.51 KDR PDGFRB
13 protein tyrosine kinase activity GO:0004713 9.4 BCR CNTRL FGF1 FGFR1 FGFR1OP FGFR1OP2
14 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.35 FGFR1 FLT3 KDR KIT PDGFRB
15 protein binding GO:0005515 10.43 BCR CNTRL FGF1 FGFR1 FGFR1OP FGFR1OP2
16 transferase activity GO:0016740 10.11 BCR FGFR1 FLT3 KDR KIT PDGFRB
17 ATP binding GO:0005524 10.06 BCR FGFR1 FLT3 KDR KIT MYO18A
18 protein homodimerization activity GO:0042803 10.02 FGFR1 FGFR1OP FGFR1OP2 FLT3 KIT TPR

Sources for 8p11 Myeloproliferative Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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