Mitral Valve Insufficiency

Categories: Cardiovascular diseases
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Aliases & Classifications for Mitral Valve Insufficiency

MalaCards integrated aliases for Mitral Valve Insufficiency:

Name: Mitral Valve Insufficiency 11 43 14 71 33
Mitral Regurgitation 11 28 53 5 14 75
Congenital Insufficiency of Mitral Valve 11 71 33
Congenital Mitral Insufficiency 11 31 33
Congenital Mitral Regurgitation 11 33
Mitral Valve Incompetence 11 33
Congenital Mitral Valve Insufficiency 33
Congenital Mitral Valve Regurgitation 33
Congenital Mitral Valve Incompetence 33
Mitral Valve Annular Incompetency 33
Congenital Mitral Incompetence 33
Mr - [mitral Regurgitation] 33
Mitral Valve Regurgitation 33
Mi - [mitral Incompetence] 33


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Disease Ontology 11 DOID:11502
ICD9CM 34 396.3 746.6
MeSH 43 D008944
NCIt 49 C50888
ICD10 31 Q23.3
UMLS 71 C0026266 C0158619 C0264774

Summaries for Mitral Valve Insufficiency

MalaCards based summary: Mitral Valve Insufficiency, also known as mitral regurgitation, is related to pulmonary hypertension and angina pectoris. An important gene associated with Mitral Valve Insufficiency is TBX5 (T-Box Transcription Factor 5), and among its related pathways/superpathways are Cardiac conduction and Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers. The drugs Ranolazine and Angiotensin II have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and whole blood, and related phenotypes are muscle and homeostasis/metabolism

Wikipedia: 75 Mitral regurgitation (MR), also known as mitral insufficiency or mitral incompetence, is a form of... more...

Related Diseases for Mitral Valve Insufficiency

Diseases in the Mitral Valve Disease family:

Mitral Valve Insufficiency

Diseases related to Mitral Valve Insufficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 774, show less)
# Related Disease Score Top Affiliating Genes
1 pulmonary hypertension 31.6 REN NPPB NPPA CRP ACE
2 angina pectoris 31.2 TNNI3 NPPB CRP ACE
3 rheumatic fever 31.2 NPPB ALB ACE
4 third-degree atrioventricular block 31.1 TNNI3 NPPB CRP ACE
5 cardiomyopathy, familial hypertrophic, 1 31.1 TNNT2 TNNT1 TNNI3 MYH6 MYH11 MYBPC3
6 coronary stenosis 31.1 TNNI3 NPPB CRP ACE
7 atrial fibrillation 31.1 TNNI3 TBX5 NR3C2 NPPB NPPA F2
8 cardiogenic shock 31.1 NPPB NPPA
9 libman-sacks endocarditis 31.0 F2 CRP
10 inferior myocardial infarction 31.0 TNNT2 TNNT1 TNNI3 NPPB ACE
11 amyloidosis 30.9 NPPB MME CRP ALB
12 cardiac sarcoidosis 30.9 NPPB CRP ACE
13 postural orthostatic tachycardia syndrome 30.9 REN FBN1 CRP
14 cardiac arrest 30.8 TNNT2 TNNI3 NPPB CRP ACE
15 transposition of the great arteries, dextro-looped 30.8 TBX5 NPPB MIR423
16 infective endocarditis 30.8 NPPB F2 CRP ALB ACE
17 atrioventricular block 30.8 TNNT2 TNNI3 TBX5 NPPB MYH6 CRP
18 endocarditis 30.8 TNNT2 TNNI3 F2 CRP ALB
19 pericarditis 30.8 TNNT2 TNNI3 NPPB CRP ACE
20 acute kidney failure 30.7 REN NPPA F2 ALB ACE
21 lipid metabolism disorder 30.6 REN CRP ALB ACE
22 sick sinus syndrome 30.6 NPPA MYH6 F2
23 congenitally corrected transposition of the great arteries 30.6 TNNT2 NPPB
24 hyperthyroidism 30.6 REN F2 CRP ALB
25 ventricular septal defect 30.6 TNNT2 TBX5 NPPB NPPA MYH6 MIR423
26 left bundle branch hemiblock 30.6 TNNT2 TNNT1 TNNI3 REN NR3C2 NPPB
27 nonbacterial thrombotic endocarditis 30.5 F2 CRP
28 peripheral vascular disease 30.5 REN F2 CRP ALB ACE
29 anomalous left coronary artery from the pulmonary artery 30.5 NPPB ACE
30 cerebrovascular disease 30.5 REN MIR423 F2 CRP ALB ACE
31 rheumatic myocarditis 30.5 TNNT2 TNNI3 CRP
32 mitral valve stenosis 30.5 REN NR3C2 NPPB NPPA F2 CRP
33 pulmonary valve insufficiency 30.5 REN NPPB FBN1 CRP ACE
34 pulmonary disease, chronic obstructive 30.5 NPPB CRP ALB ACE
35 behcet syndrome 30.5 F2 CRP ALB ACE
36 transient cerebral ischemia 30.5 REN NPPB F2 CRP ALB ACE
37 amyloidosis, hereditary, transthyretin-related 30.5 TNNT2 NPPB MYBPC3 ALB
38 aortic aneurysm 30.5 REN MYH11 FBN1 F2 CRP ALB
39 aortic valve disease 1 30.4 TBX5 REN NPPB MYH6 MYH11 MIR423
40 myocardial stunning 30.4 TNNT2 TNNT1 TNNI3 NPPB ACE
41 wolff-parkinson-white syndrome 30.4 TNNT2 TBX5 NPPB MYH6 MYBPC3
42 anterolateral myocardial infarction 30.4 NPPB NPPA ACE
43 aortic aneurysm, familial thoracic 1 30.4 REN NDE1 MYH6 MYH11 FBN1 CRP
44 cardiac tamponade 30.4 TNNI3 REN NPPB F2 CRP ALB
45 heart septal defect 30.4 TNNT2 TBX5 NPPB NPPA MYH6 MIR423
46 nutritional deficiency disease 30.4 F2 CRP ALB
47 aortic valve insufficiency 30.4 TNNI3 REN NPPB MYH11 FBN1 F2
48 left ventricular noncompaction 30.4 TNNT2 TNNI3 TBX5 MYH6 MYBPC3 FBN1
49 aortic aneurysm, familial abdominal, 1 30.3 REN MYH11 FBN1 CRP ALB ACE
50 glomerulonephritis 30.3 REN CRP ALB ACE
51 coronary artery vasospasm 30.3 TNNT2 TNNT1 TNNI3 REN NPPB CRP
52 intestinal obstruction 30.3 F2 CRP ALB
53 lemierre's syndrome 30.3 F2 CRP
54 syphilis 30.3 CRP ALB ACE
55 ebstein anomaly 30.3 TBX5 NPPB MYH6 MYBPC3
56 right bundle branch block 30.3 TNNT2 TNNI3 NPPB CRP ACE
57 sleep apnea 30.3 REN NPPB CRP ALB ACE
58 henoch-schoenlein purpura 30.3 CRP ALB ACE
59 limb ischemia 30.3 CRP ALB ACE
60 carotid artery disease 30.3 CRP ALB ACE
61 pulmonary edema 30.3 TNNT2 TNNI3 REN NPPB NPPA F2
62 central sleep apnea 30.3 REN NPPB CRP ACE
63 orthostatic intolerance 30.2 TBX5 REN MYH6 MYH11 MIR423 FBN1
64 first-degree atrioventricular block 30.2 TNNI3 NPPB CRP ACE
65 moyamoya disease 1 30.2 MYH11 F2 CRP
66 stroke, ischemic 30.2 REN NR3C2 NPPB NPPA FBN1 F2
67 subacute bacterial endocarditis 30.2 CRP ALB
68 cholecystitis 30.2 F2 CRP ALB
69 respiratory failure 30.2 TNNI3 REN NPPB F2 CRP ALB
70 splenic infarction 30.2 F2 CRP ALB
71 intermediate coronary syndrome 30.2 TNNT2 TNNT1 TNNI3 REN NPPB MIR423
72 silent myocardial infarction 30.2 TNNT2 TNNI3 CRP ACE
73 apnea, obstructive sleep 30.2 REN NR3C2 NPPB CRP ALB ACE
74 uremia 30.2 REN CRP ALB ACE
75 vascular disease 30.1 FBN1 F2 CRP ALB ACE
76 autosomal dominant polycystic kidney disease 30.1 REN CRP ALB ACE
77 inguinal hernia 30.1 FBN1 F2 CRP ALB
78 constrictive pericarditis 30.1 TNNT2 TNNI3 REN NPPB MYBPC3 CRP
79 intracranial embolism 30.1 F2 CRP ALB ACE
80 portal hypertension 30.1 REN F2 ALB
81 exanthem 30.1 F2 CRP ALB ACE
82 nonobstructive coronary artery disease 30.1 TNNT2 TNNT1 TNNI3 NPPB CRP ACE
83 alcohol use disorder 30.1 F2 CRP ALB ACE
84 hemopericardium 30.1 TNNI3 NPPB FBN1 F2 CRP
85 gilbert syndrome 30.0 F2 CRP ALB
86 aortic disease 30.0 REN NPPB MYH11 MIR423 FBN1 CRP
87 kidney disease 30.0 REN NR3C2 NPPB NPPA CRP ALB
88 pheochromocytoma 30.0 REN NPPA MME CRP ACE
89 noonan syndrome 1 30.0 TBX5 NPPA MYH6 MYBPC3 FBN1
90 arteries, anomalies of 30.0 TNNI3 REN MIR423 CRP ALB ACE
91 aortic dissection 30.0 TNNT2 TNNI3 REN NPPB MYH11 FBN1
92 hypothyroidism 30.0 REN NPPB F2 CRP ALB ACE
93 pancytopenia 29.9 MME F2 CRP ALB ACE
94 immunoglobulin light chain amyloidosis 29.9 TNNT2 TNNT1 TNNI3 NPPB ALB
95 deficiency anemia 29.9 REN MME F2 CRP ALB ACE
96 systolic heart failure 29.9 TNNT2 TNNI3 REN NR3C2 NPPB MYH6
97 myopathy 29.9 TNNT2 TNNT1 TNNI3 MYH6 MYH11 MIR423
98 peripartum cardiomyopathy 29.8 NR3C2 NPPB MYH6 MYBPC3 MIR423 ACE
99 pre-eclampsia 29.8 REN NPPA F2 CRP ALB ACE
100 pericardial effusion 29.8 TNNT2 TNNT1 TNNI3 REN NPPB NPPA
101 acute myocarditis 29.7 TNNT2 TNNT1 TNNI3 REN NPPB CRP
102 type 2 diabetes mellitus 29.7 REN NR3C2 NPPB MIR423 F2 CRP
103 cardiovascular system disease 29.7 REN NR3C2 NPPB NPPA MME MIR423
104 pulmonary embolism 29.7 TNNT2 TNNT1 TNNI3 NPPB F2 CRP
105 hypertensive heart disease 29.7 TNNT2 TNNI3 REN NR3C2 NPPB NPPA
106 restrictive cardiomyopathy 29.7 TNNT2 TNNT1 TNNI3 REN NR3C2 NPPB
107 aortic valve disease 2 29.6 TNNT2 TNNI3 TBX5 REN NPPB NPPA
108 chronic kidney disease 29.6 TNNT2 TNNI3 REN NR3C2 NPPB NPPA
109 diabetes mellitus 29.6 TNNT2 REN NR3C2 NPPB NPPA F2
110 diastolic heart failure 29.5 TNNT2 TNNI3 REN NR3C2 NPPB MYH6
111 atrial heart septal defect 29.5 TNNT2 TNNI3 TBX5 REN NPPB NPPA
112 congestive heart failure 29.4 TNNT2 TNNI3 REN NR3C2 NPPB NPPA
113 acute myocardial infarction 29.4 TNNT2 TNNI3 REN NR3C2 NPPB NPPA
114 myocarditis 29.4 TNNT2 TNNT1 TNNI3 NPPB NPPA MYH6
115 hypertension, essential 29.4 TNNT2 TNNI3 REN NR3C2 NPPB NPPA
116 tetralogy of fallot 29.2 TNNT2 TNNI3 TBX5 REN NPPB NPPA
117 patent ductus arteriosus 1 29.1 TNNT2 TBX5 REN NPPB MYH6 MYH11
118 heart valve disease 29.1 TNNT2 TNNI3 REN NR3C2 NPPB NPPA
119 mitral valve disease 29.0 TNNT2 TNNT1 TNNI3 REN NR3C2 NPPB
120 tricuspid valve insufficiency 29.0 TNNT2 TNNT1 TNNI3 REN NR3C2 NPPB
121 hypertrophic cardiomyopathy 29.0 TNNT2 TNNT1 TNNI3 TBX5 REN NR3C2
122 myocardial infarction 28.9 TNNT2 TNNT1 TNNI3 REN NR3C2 NPPB
123 patent foramen ovale 28.9 TNNT2 TNNI3 TBX5 REN NPPB NPPA
124 tricuspid valve disease 28.6 TNNT2 TNNT1 TNNI3 TBX5 REN NR3C2
125 dilated cardiomyopathy 28.6 TNNT2 TNNT1 TNNI3 TBX5 REN NR3C2
126 heart disease 28.5 TNNT2 TNNI3 TBX5 REN NR3C2 NPPB
127 lipoprotein quantitative trait locus 28.4 TNNT2 TNNT1 TNNI3 TBX5 REN NPPB
128 macrothrombocytopenia with mitral valve insufficiency 11.6
129 cardiospondylocarpofacial syndrome 11.6
130 congenital mitral valve insufficiency and/or stenosis 11.3
131 arachnodactyly - intellectual disability - dysmorphism 11.3
132 intellectual developmental disorder, x-linked, syndromic, hackmann-di donato type 11.3
133 cardiomyopathy, dilated, 1e 11.2
134 ehlers-danlos syndrome, cardiac valvular type 11.1
135 mitral valve prolapse 2 11.1
136 mitral valve prolapse 3 11.1
137 progressive familial heart block, type ia 10.6
138 progressive familial heart block 10.6
139 broken heart syndrome 10.6
140 parkinson disease, late-onset 10.6
141 visceral myopathy 2 10.4 NDE1 MYH11
142 mediastinum teratoma 10.4 CRP ACE
143 pyeloureteritis cystica 10.4 REN CRP
144 subvalvular aortic stenosis 10.4
145 vasculogenic impotence 10.4 NPPA ACE
146 spontaneous tension pneumothorax 10.4 NPPB CRP
147 vaginal adenosarcoma 10.4 MME CRP
148 anterior scleritis 10.4 CRP ACE
149 renal artery obstruction 10.4 REN ACE
150 oculodentodigital dysplasia 10.4
151 papillon-lefevre syndrome 10.4
152 posterolateral myocardial infarction 10.4
153 multiple cranial nerve palsy 10.4 CRP ACE
154 posterior scleritis 10.4 CRP ACE
155 intestinal tuberculosis 10.4 CRP ALB
156 epicardium cancer 10.4 TNNI3 CRP
157 hypertension, diastolic 10.4 REN ACE
158 pulmonary valve disease 10.4 TBX5 NPPB FBN1
159 glossopharyngeal nerve disease 10.4 CRP ACE
160 granulomatous angiitis 10.4 CRP ACE
161 systemic lupus erythematosus 10.4
162 xanthogranulomatous pyelonephritis 10.4 MME CRP
163 aortic aneurysm, familial thoracic 4 10.4 NDE1 MYH11 FBN1
164 chronic duodenal ileus 10.4 CRP ALB
165 orbital osteomyelitis 10.4 F2 CRP
166 hypertensive nephropathy 10.4 ALB ACE
167 pyridoxine deficiency anemia 10.4 F2 ACE
168 neuroretinitis 10.4 CRP ACE
169 baastrup's syndrome 10.4 MME CRP
170 klebsiella pneumonia 10.4 CRP ALB
171 optic papillitis 10.4 CRP ACE
172 familial isolated restrictive cardiomyopathy 10.4 TNNT2 TNNI3
173 achenbach syndrome 10.4 F2 CRP
174 hypoaldosteronism 10.4 REN NPPA ACE
175 ankylosing spondylitis 3 10.4 CRP ALB
176 atrial standstill 1 10.4
177 lupus erythematosus 10.4
178 pectus carinatum 10.4 TNNT1 FBN1
179 toxic myocarditis 10.4 TNNI3 NPPB ACE
180 synovial angioma 10.4 F2 CRP
181 emphysematous cholecystitis 10.4 F2 CRP
182 femoral neuropathy 10.4 F2 CRP
183 blue toe syndrome 10.4 F2 CRP
184 pure autonomic failure 10.4 REN NPPA ACE
185 chronic pulmonary heart disease 10.4 REN NPPB ACE
186 granulomatous dermatitis 10.4 CRP ACE
187 orbital disease 10.4 MME FBN1 CRP
188 chronic intestinal vascular insufficiency 10.4 CRP ALB
189 acute vascular insufficiency of intestine 10.3 CRP ALB
190 peptic ulcer perforation 10.3 CRP ALB
191 tolosa-hunt syndrome 10.3 CRP ACE
192 urogenital tuberculosis 10.3 CRP ALB
193 orbital cellulitis 10.3 CRP ACE
194 renal pelvis squamous cell carcinoma 10.3 F2 CRP
195 acute orbital inflammation 10.3 CRP ACE
196 hematocele of tunica vaginalis testis 10.3 F2 CRP
197 tuberculous peritonitis 10.3 CRP ALB
198 long covid 10.3 REN CRP ACE
199 uterine inversion 10.3 MME F2
200 waterhouse-friderichsen syndrome 10.3 F2 CRP
201 graves disease 1 10.3
202 systemic lupus erythematosus 1 10.3
203 antiphospholipid syndrome 10.3
204 internal hemorrhoid 10.3 F2 CRP
205 cavernous sinus thrombosis 10.3 F2 CRP
206 pyelonephritis 10.3 CRP ALB ACE
207 viral exanthem 10.3 CRP ACE
208 marfan syndrome 10.3
209 rheumatic heart disease 10.3
210 interatrial communication 10.3
211 superior mesenteric artery syndrome 10.3 CRP ALB
212 critical illness polyneuropathy 10.3 CRP ALB
213 ureteric orifice cancer 10.3 FBN1 F2
214 polycystic kidney disease 4 10.3 TNNT2 REN NPPB
215 hydrops of gallbladder 10.3 NPPB CRP ALB
216 subdural empyema 10.3 F2 CRP
217 mesenteric lymphadenitis 10.3 NPPB CRP ALB
218 tracheal disease 10.3 FBN1 CRP ALB
219 bacterial conjunctivitis 10.3 NPPB CRP ALB
220 granulomatous hepatitis 10.3 CRP ALB ACE
221 adrenal gland disease 10.3 REN NR3C2 ACE
222 carotid stenosis 10.3 REN CRP ACE
223 orthostatic proteinuria 10.3 REN ALB ACE
224 miliary tuberculosis 10.3 CRP ALB ACE
225 hemopneumothorax 10.3 F2 CRP
226 renal tuberculosis 10.3 REN CRP ALB
227 bell's palsy 10.3 CRP ALB ACE
228 branch retinal artery occlusion 10.3 F2 CRP
229 renal artery atheroma 10.3 REN ALB ACE
230 kidney papillary necrosis 10.3 REN ALB ACE
231 iritis 10.3 CRP ALB ACE
232 giant hemangioma 10.3 F2 ALB
233 mononeuropathy 10.3 CRP ALB ACE
234 lymph node tuberculosis 10.3 CRP ALB
235 severe nonproliferative diabetic retinopathy 10.3 REN ALB ACE
236 fibrosis of extraocular muscles, congenital, 1 10.3
237 cor triatriatum 10.3
238 subclavian steal syndrome 10.3 F2 CRP ACE
239 prostatic hypertrophy 10.3 CRP ALB ACE
240 kidney hypertrophy 10.3 REN ALB ACE
241 late congenital syphilis 10.3 F2 CRP
242 gastric dilatation 10.3 TNNI3 CRP ALB
243 melkersson-rosenthal syndrome 10.3 CRP ACE
244 facial nerve disease 10.3 CRP ALB ACE
245 facial paralysis 10.3 CRP ALB ACE
246 diabetic autonomic neuropathy 10.3 REN ALB ACE
247 hypersensitivity reaction type iii disease 10.3 CRP ALB ACE
248 hepatopulmonary syndrome 10.3 CRP ALB ACE
249 neurogenic bladder 10.3 CRP ALB ACE
250 lymph node disease 10.3 NPPB CRP ALB
251 pseudohypoaldosteronism, type i, autosomal dominant 10.3 REN NR3C2
252 conjunctival disease 10.3 CRP ALB ACE
253 microvascular complications of diabetes 3 10.3 REN ALB ACE
254 autosomal recessive nonsyndromic deafness 32 10.3 TNNT2 TNNT1
255 coccidiosis 10.3 CRP ALB ACE
256 newborn respiratory distress syndrome 10.3 REN CRP ALB
257 arthrogryposis, distal, type 2b2 10.3 TNNT2 TNNT1
258 thyroid gland disease 10.3 CRP ALB ACE
259 intestinal pseudo-obstruction 10.3 NDE1 MYH11 ALB
260 hepatic tuberculosis 10.3 F2 ALB
261 lens disease 10.3 FBN1 ALB ACE
262 intracranial sinus thrombosis 10.3 F2 CRP
263 holt-oram syndrome 10.3 TBX5 NPPA MYH6
264 hypersensitivity reaction type iv disease 10.3 CRP ALB ACE
265 cardiomyopathy, familial hypertrophic, 20 10.3 F2 ALB
266 critical covid-19 10.3 F2 CRP ACE
267 ureteral disease 10.3 REN ALB ACE
268 cardiac tuberculosis 10.3 NR3C2 NPPB CRP ACE
269 malignant hypertension 10.3 REN NPPB NPPA ACE
270 obstructive nephropathy 10.3 REN ALB ACE
271 esophageal tuberculosis 10.3 CRP ALB
272 parathyroid gland disease 10.3 REN CRP ALB
273 hepatic infarction 10.3 F2 ALB
274 abducens palsy 10.3 F2 CRP
275 cerebritis 10.3 CRP ALB
276 mitochondrial dna depletion syndrome 12b 10.3 MYH6 MYBPC3 FBN1
277 retinal artery occlusion 10.3 F2 CRP ACE
278 cranial nerve disease 10.3 CRP ALB ACE
279 background diabetic retinopathy 10.3 MIR423 ALB ACE
280 spondyloarthropathy 1 10.3
281 sarcoidosis 1 10.3
282 neuraminidase deficiency 10.3
283 brittle bone disorder 10.3
284 sarcoidosis 2 10.3
285 connective tissue disease 10.3
286 spondylitis 10.3
287 syncope 10.3
288 discitis 10.3 CRP ALB
289 nephrosclerosis 10.3 NR3C2 F2 ACE
290 beta-lactam allergy 10.3 CRP ALB
291 uveal disease 10.3 CRP ALB ACE
292 thoracic outlet syndrome 10.3 F2 CRP
293 acalculous cholecystitis 10.3 F2 CRP ALB
294 epidural abscess 10.3 F2 CRP ALB
295 splenic abscess 10.3 F2 CRP ALB
296 ascending cholangitis 10.3 F2 CRP ALB
297 cholangitis 10.3 F2 CRP ALB
298 suppurative cholangitis 10.3 F2 CRP ALB
299 ureterolithiasis 10.3 F2 CRP ALB
300 early congenital syphilis 10.3 F2 CRP ALB
301 ankylosing spondylitis 1 10.3 F2 CRP ALB
302 gastrointestinal tuberculosis 10.3 F2 CRP ALB
303 acute cholangitis 10.3 F2 CRP ALB
304 abdominal tuberculosis 10.3 F2 CRP ALB
305 paralytic ileus 10.3 F2 CRP ALB
306 splenic tuberculosis 10.3 F2 CRP ALB
307 necrotizing gastritis 10.3 F2 CRP ALB
308 drug-induced hepatitis 10.3 F2 CRP ALB
309 intracranial hypotension 10.3 F2 CRP ALB
310 pyuria 10.3 F2 CRP ALB
311 ischemic colitis 10.3 F2 CRP ALB
312 peliosis hepatis 10.3 F2 ALB
313 active peptic ulcer disease 10.3 F2 CRP ALB
314 common bile duct disease 10.3 F2 CRP ALB
315 analbuminemia 10.3 F2 CRP ALB
316 kwashiorkor 10.3 F2 CRP ALB
317 hemorrhoid 10.3 F2 CRP ALB
318 compartment syndrome 10.3 F2 CRP ALB
319 heart aneurysm 10.2 NPPB CRP ALB ACE
320 coronary aneurysm 10.2 NPPB CRP ALB ACE
321 necrotizing fasciitis 10.2 F2 CRP ALB
322 esophageal varix 10.2 F2 CRP ALB
323 alcoholic cardiomyopathy 10.2 TNNT2 REN NPPB ACE
324 choledocholithiasis 10.2 F2 CRP ALB
325 intestinal perforation 10.2 F2 CRP ALB
326 cecal disease 10.2 F2 CRP ALB
327 thrombophlebitis 10.2 F2 CRP ALB
328 portal vein thrombosis 10.2 F2 CRP ALB
329 protein-losing enteropathy 10.2 F2 CRP ALB
330 cellulitis 10.2 F2 CRP ALB
331 autoimmune disease of blood 10.2 F2 CRP ALB
332 obstructive jaundice 10.2 F2 CRP ALB
333 renal artery disease 10.2 REN CRP ALB ACE
334 lateral myocardial infarction 10.2
335 vasculitis 10.2
336 hypereosinophilic syndrome 10.2
337 quadricuspid aortic valve 10.2
338 generalized atherosclerosis 10.2 REN CRP ALB ACE
339 arteriolosclerosis 10.2 REN CRP ALB ACE
340 rapidly progressive glomerulonephritis 10.2 REN CRP ALB ACE
341 blood protein disease 10.2 F2 CRP ALB
342 pyelitis 10.2 REN CRP ALB ACE
343 diabetes mellitus, ketosis-prone 10.2 REN CRP ALB ACE
344 sclerosing cholangitis 10.2 F2 CRP ALB
345 vulvar leiomyoma 10.2 MYH11 MME
346 autonomic nervous system disease 10.2 REN CRP ALB ACE
347 interstitial nephritis 10.2 REN CRP ALB ACE
348 typhoid fever 10.2 F2 CRP ALB
349 cystic kidney disease 10.2 REN CRP ALB ACE
350 urinary tract obstruction 10.2 REN CRP ALB ACE
351 hyperuricemia 10.2 REN CRP ALB
352 sleep disorder 10.2 REN CRP ALB ACE
353 membranoproliferative glomerulonephritis 10.2 REN CRP ALB ACE
354 autoimmune disease of endocrine system 10.2 REN CRP ALB ACE
355 cholesterol embolism 10.2 REN F2 CRP ACE
356 hepatic coma 10.2 F2 ALB
357 atrioventricular septal defect 10.2
358 49, xxxxy syndrome 10.2
359 49,xxxxx syndrome 10.2
360 49,xyyyy syndrome 10.2
361 gastroenteritis 10.2 REN CRP ALB
362 hemorrhagic disease 10.2 F2 CRP ALB
363 hepatic encephalopathy 10.2 NPPA F2 ALB
364 danon disease 10.2 TNNT2 MYH6 MYBPC3
365 pleural disease 10.2 F2 CRP ALB
366 viral pneumonia 10.2 REN F2 CRP ACE
367 vesicoureteral reflux 10.2 REN CRP ALB ACE
368 actinomycosis 10.2 CRP ALB
369 hypokalemia 10.2 REN NR3C2 ALB ACE
370 blood coagulation disease 10.2 F2 CRP ALB
371 placenta disease 10.2 REN F2 CRP
372 barth syndrome 10.2 TNNT2 MYH6 MYBPC3
373 secondary syphilis 10.2 CRP ACE
374 polycythemia 10.2 REN F2 CRP ACE
375 central pontine myelinolysis 10.2 REN ALB
376 thrombocytosis 10.2 F2 CRP ALB
377 familial atrial fibrillation 10.2 TBX5 NPPA MYH6 MYBPC3
378 alcoholic hepatitis 10.2 F2 CRP ALB
379 congenital unguarded mitral orifice 10.2
380 mitral valve agenesis 10.2
381 retinal vascular disease 10.2 REN MIR423 ALB ACE
382 angioedema 10.2 MME F2 CRP ACE
383 polycystic liver disease 1 with or without kidney cysts 10.2
384 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.2
385 graves' disease 10.2
386 ehlers-danlos syndrome 10.2
387 systemic scleroderma 10.2
388 end stage renal disease 10.2
389 mediastinitis 10.2 F2 CRP ALB ACE
390 diffuse alveolar hemorrhage 10.2
391 cranial nerve palsy 10.2 F2 CRP ALB ACE
392 drug allergy 10.2 F2 CRP ALB ACE
393 papilledema 10.2 F2 CRP ALB ACE
394 aspiration pneumonia 10.2 F2 CRP ALB ACE
395 integumentary system disease 10.2 MIR423 CRP ALB ACE
396 chickenpox 10.2 F2 CRP ALB ACE
397 vein disease 10.2 F2 CRP ALB ACE
398 peptic ulcer disease 10.2 F2 CRP ALB ACE
399 schistosomiasis 10.2 F2 CRP ALB
400 autoimmune disease of gastrointestinal tract 10.2 F2 CRP ALB
401 bronchial disease 10.2 CRP ALB ACE
402 hemoglobinopathy 10.2 F2 CRP ALB
403 volvulus of midgut 10.2 TNNI3 F2 CRP ALB
404 noonan syndrome with multiple lentigines 10.2 TNNT2 TBX5 MYH6 MYBPC3
405 hepatic vascular disease 10.2 REN F2 CRP ALB
406 substance abuse 10.2 F2 CRP ALB ACE
407 primary bacterial infectious disease 10.2 CRP ALB ACE
408 pleural empyema 10.2 MME F2 CRP ALB
409 eclampsia 10.2 REN F2 ALB ACE
410 plasma protein metabolism disease 10.2 MME F2 CRP ALB
411 splenic disease 10.2 MME F2 CRP ALB
412 iga glomerulonephritis 10.2 REN ALB ACE
413 speech and communication disorders 10.2 F2 CRP ALB ACE
414 oligohydramnios 10.2 REN NPPB CRP ALB ACE
415 acute kidney tubular necrosis 10.2 REN NPPA CRP ALB ACE
416 acute anterolateral myocardial infarction 10.2 TNNT1 REN NPPB CRP ACE
417 long qt syndrome 1 10.1 TNNT2 TBX5 MYH6 MYBPC3
418 cardiomyopathy, dilated, 1b 10.1 TNNT2 TNNI3 MYH6 MYBPC3
419 hypertensive retinopathy 10.1 REN NR3C2 CRP ALB ACE
420 sickle cell anemia 10.1 F2 CRP ALB
421 urinary system disease 10.1 REN MIR423 ALB ACE
422 renal hypertension 10.1 REN NR3C2 CRP ALB ACE
423 mineral metabolism disease 10.1 REN NR3C2 CRP ALB ACE
424 familial isolated dilated cardiomyopathy 10.1 TNNT2 TNNI3 MYH6 MYBPC3
425 hydronephrosis 10.1 REN MYH11 MME CRP ALB
426 chronic pyelonephritis 10.1 REN MME CRP ALB ACE
427 duodenal obstruction 10.1 CRP ALB
428 coronary heart disease 1 10.1
429 muscle hypertrophy 10.1
430 endomyocardial fibrosis 10.1
431 hemolytic anemia 10.1
432 dextrocardia 10.1
433 acute pulmonary heart disease 10.1 TNNI3 REN NPPB F2 CRP
434 chromosome 1p36 deletion syndrome 10.1 TBX5 MYH6 MYBPC3
435 catecholaminergic polymorphic ventricular tachycardia 10.1 TNNT2 MYH6 MYBPC3
436 pectus excavatum 10.1
437 scleroderma, familial progressive 10.1
438 supravalvular aortic stenosis 10.1
439 williams-beuren syndrome 10.1
440 elsahy-waters syndrome 10.1
441 laron syndrome 10.1
442 ataxia with vitamin e deficiency 10.1
443 abdominal obesity-metabolic syndrome 1 10.1
444 thrombosis 10.1
445 split hand-foot malformation 10.1
446 hemiplegia 10.1
447 relapsing polychondritis 10.1
448 purpura 10.1
449 posteroinferior myocardial infarction 10.1
450 complete atrioventricular canal 10.1
451 cor triatriatum sinister 10.1
452 coronary artery aneurysm 10.1
453 isolated split hand-split foot malformation 10.1
454 acquired metabolic disease 10.1 REN MIR423 CRP ALB ACE
455 overnutrition 10.1 REN MIR423 CRP ALB ACE
456 endocardium disease 10.1 NPPB F2 CRP ALB ACE
457 wilms tumor 1 10.1 REN MME MIR423 ALB
458 glucose metabolism disease 10.1 REN MIR423 CRP ALB ACE
459 carbohydrate metabolic disorder 10.1 REN MIR423 CRP ALB ACE
460 inherited metabolic disorder 10.1 REN MIR423 CRP ALB ACE
461 aspiration pneumonitis 10.1 CRP ALB
462 liver cirrhosis 10.1 REN NPPA F2 ALB
463 hepatorenal syndrome 10.1 REN NPPA F2 ALB ACE
464 severe covid-19 10.1 REN F2 CRP ALB ACE
465 hypertensive encephalopathy 10.1 REN F2 CRP ALB ACE
466 hypersensitivity vasculitis 10.1 REN F2 CRP ALB ACE
467 arrhythmogenic right ventricular cardiomyopathy 10.1 TNNT2 TNNI3 MYH6 MYBPC3
468 supine hypotensive syndrome 10.1 REN NR3C2 F2 CRP ALB
469 inappropriate adh syndrome 10.1 REN NPPB NPPA CRP ALB ACE
470 hemolytic uremic syndrome, atypical 1 10.1 F2 CRP ALB
471 renovascular hypertension 10.1 REN NR3C2 NPPB NPPA ALB ACE
472 intracranial berry aneurysm 10.1 TNNI3 REN F2 CRP ALB
473 migraine with or without aura 1 10.1 REN F2 CRP ALB ACE
474 intermittent claudication 10.1 TNNT2 F2 CRP ALB ACE
475 gas gangrene 10.1 TNNT2 TNNT1 TNNI3 CRP ALB
476 aneurysm of sinus of valsalva 10.1
477 congenital gerbode defect 10.1
478 long qt syndrome 10.1 TNNT2 TNNI3 TBX5 MYH6 MYBPC3
479 conn's syndrome 10.1 REN NR3C2 NPPA CRP ALB ACE
480 acute cor pulmonale 10.0 TNNI3 REN NPPB F2 CRP ACE
481 covid-19 10.0 TNNI3 REN NPPB F2 CRP ACE
482 inflammatory and toxic neuropathy 10.0 CRP ALB
483 peripheral artery disease 10.0 REN NPPB MIR423 CRP ALB ACE
484 total anomalous pulmonary venous return 1 10.0
485 autoimmune disease 10.0
486 cardiomyopathy, dilated, 1a 10.0
487 contractural arachnodactyly, congenital 10.0
488 thrombocythemia 1 10.0
489 thrombocytopenic purpura, autoimmune 10.0
490 varicose veins 10.0
491 charge syndrome 10.0
492 trichohepatoenteric syndrome 1 10.0
493 factor vii deficiency 10.0
494 lymphoma, hodgkin, classic 10.0
495 mucolipidosis ii alpha/beta 10.0
496 ocular motor apraxia 10.0
497 hyperphenylalaninemia, bh4-deficient, a 10.0
498 rhabdomyosarcoma 2 10.0
499 congenital hemidysplasia with ichthyosiform erythroderma and limb defects 10.0
500 progressive familial heart block, type ib 10.0
501 body mass index quantitative trait locus 1 10.0
502 hypereosinophilic syndrome, idiopathic 10.0
503 hemorrhage, intracerebral 10.0
504 intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies 10.0
505 mucopolysaccharidosis-plus syndrome 10.0
506 primary progressive multiple sclerosis 10.0
507 acquired von willebrand syndrome 10.0
508 adult respiratory distress syndrome 10.0
509 familial hyperlipidemia 10.0
510 cystic echinococcosis 10.0
511 echinococcosis 10.0
512 thrombocytopenia due to platelet alloimmunization 10.0
513 post-traumatic stress disorder 10.0
514 essential thrombocythemia 10.0
515 gastric antral vascular ectasia 10.0
516 epidermolysis bullosa 10.0
517 ischemia 10.0
518 loeffler endocarditis 10.0
519 aortitis 10.0
520 discrete subaortic stenosis 10.0
521 apical myocardial infarction 10.0
522 acute stress disorder 10.0
523 situs inversus 10.0
524 classic ehlers-danlos syndrome 10.0
525 pik3ca-related overgrowth spectrum 10.0
526 48,xxxy syndrome 10.0
527 48,xxyy syndrome 10.0
528 48,xyyy 10.0
529 aortopulmonary window 10.0
530 atrial septal defect coronary sinus 10.0
531 children's interstitial lung disease 10.0
532 chromosomal triplication 10.0
533 dextrocardia with situs inversus 10.0
534 ring chromosome 6 10.0
535 congenital aortopulmonary window 10.0
536 pik3ca-related overgrowth syndrome 10.0
537 overgrowth syndrome 10.0
538 bladder cancer 10.0
539 alagille syndrome 1 10.0
540 palmoplantar keratoderma, epidermolytic 10.0
541 lipomatosis, multiple 10.0
542 thrombophilia due to thrombin defect 10.0
543 hyperoxaluria, primary, type i 10.0
544 spastic paraplegia 20, autosomal recessive 10.0
545 woolly hair, hypotrichosis, everted lower lip, and outstanding ears 10.0
546 bacteremia 2 10.0
547 immunodeficiency, common variable, 10 10.0
548 stickler syndrome 10.0
549 polymyositis 10.0
550 familial woolly hair syndrome 10.0
551 myopia 10.0
552 coronary thrombosis 10.0
553 hereditary spastic paraplegia 10.0
554 primary hyperoxaluria 10.0
555 interstitial lung disease 10.0
556 palmoplantar keratosis 10.0
557 paraplegia 10.0
558 evans' syndrome 10.0
559 hypermobile ehlers-danlos syndrome 10.0
560 cor triatriatum dexter 10.0
561 disorder of glyoxylate metabolism 10.0
562 intracranial hypertension 10.0 REN NPPB F2 CRP ALB ACE
563 eye disease 10.0 REN MIR423 FBN1 CRP ALB ACE
564 anuria 10.0 REN NR3C2 F2 CRP ALB ACE
565 urinary tract infection 10.0 REN NR3C2 F2 CRP ALB ACE
566 physical disorder 10.0 TBX5 NDE1 MYH6 MIR423 CRP ALB
567 non-severe covid-19 10.0 TNNI3 REN F2 CRP ALB ACE
568 peripheral nervous system disease 10.0 REN MME MIR423 CRP ALB ACE
569 nephrotic syndrome 10.0 REN NPPA F2 CRP ALB ACE
570 kabuki syndrome 1 10.0
571 down syndrome 10.0
572 heart cancer 10.0
573 congenital mitral malformation 10.0
574 double-orifice mitral valve 10.0
575 cardiac conduction defect 10.0
576 coarctation of aorta 10.0
577 macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss 10.0
578 mitral valve prolapse 1 10.0
579 neutrophilia, hereditary 10.0
580 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 10.0
581 pulmonary hypertension, primary, 1 10.0
582 fetal akinesia deformation sequence 1 10.0
583 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 10.0
584 goodpasture syndrome 10.0
585 myasthenia gravis 10.0
586 myasthenic syndrome, congenital, 10 10.0
587 chromosome 18q deletion syndrome 10.0
588 ventricular fibrillation, paroxysmal familial, 1 10.0
589 legionnaire disease 10.0
590 kawasaki disease 10.0
591 hyperlipoproteinemia, type iii 10.0
592 helix syndrome 10.0
593 legionellosis 10.0
594 qualitative platelet defect 10.0
595 reading disorder 10.0
596 thrombocytopenia 10.0
597 blood platelet disease 10.0
598 congenital myasthenic syndrome 10.0
599 pneumonia 10.0
600 hemoglobinuria 10.0
601 posterior myocardial infarction 10.0
602 adenoma 10.0
603 extrinsic allergic alveolitis 10.0
604 bacterial pneumonia 10.0
605 heroin dependence 10.0
606 47 xxx syndrome 10.0
607 distomatosis 10.0
608 double discordia 10.0
609 proximal chromosome 18q deletion syndrome 10.0
610 pulmonary sequestration 10.0
611 cleft mitral valve 10.0
612 distal arthrogryposis 10.0 TNNT1 MYH6 MYBPC3 FBN1
613 hypoplastic left heart syndrome 9.9 TNNT2 TNNI3 TBX5 NPPB NPPA MYH6
614 rasopathy 9.9 TNNT2 TNNI3 TBX5 MYH6 MYH11 MYBPC3
615 univentricular heart 9.9
616 coronavirus infectious disease 9.9 TNNI3 REN NPPB F2 CRP ALB
617 brugada syndrome 9.9 TNNT2 TNNI3 TBX5 NPPA MYH6 MYBPC3
618 myasthenic syndrome, congenital, 20, presynaptic 9.9 TNNT2 MYH6
619 breast cancer 9.9
620 carcinoid tumors, intestinal 9.9
621 cat eye syndrome 9.9
622 coronary artery dissection, spontaneous 9.9
623 ehlers-danlos syndrome, classic type, 1 9.9
624 ehlers-danlos syndrome, vascular type 9.9
625 epidermolysis bullosa dystrophica, pretibial 9.9
626 photoparoxysmal response 1 9.9
627 factor viii deficiency 9.9
628 lymphangiectasia, intestinal 9.9
629 osteogenesis imperfecta, type i 9.9
630 pneumothorax, primary spontaneous 9.9
631 polycystic kidney disease 1 with or without polycystic liver disease 9.9
632 greig cephalopolysyndactyly syndrome 9.9
633 anemia, autoimmune hemolytic 9.9
634 atrioventricular dissociation 9.9
635 type 1 diabetes mellitus 9.9
636 endocardial fibroelastosis 9.9
637 trichothiodystrophy 4, nonphotosensitive 9.9
638 heart block, congenital 9.9
639 hydrops fetalis, nonimmune 9.9
640 epilepsy, progressive myoclonic, 4, with or without renal failure 9.9
641 neurodegeneration with brain iron accumulation 2a 9.9
642 ceroid lipofuscinosis, neuronal, 1 9.9
643 multicentric osteolysis, nodulosis, and arthropathy 9.9
644 pseudoxanthoma elasticum 9.9
645 pulmonary arteriovenous fistulas 9.9
646 pulmonary atresia with intact ventricular septum 9.9
647 inflammatory bowel disease 1 9.9
648 intellectual developmental disorder, x-linked, syndromic, cabezas type 9.9
649 carnitine palmitoyltransferase ii deficiency, infantile 9.9
650 gallbladder disease 1 9.9
651 chudley-mccullough syndrome 9.9
652 lymphoma, non-hodgkin, familial 9.9
653 caspase 8 deficiency 9.9
654 resting heart rate, variation in 9.9
655 coronary heart disease 4 9.9
656 cardiomyopathy, dilated, 1o 9.9
657 granulomatosis with polyangiitis 9.9
658 aplastic anemia 9.9
659 malaria 9.9
660 ewing sarcoma 9.9
661 glass syndrome 9.9
662 leukemia, acute lymphoblastic 9.9
663 osteogenesis imperfecta, type vi 9.9
664 myelodysplastic syndrome 9.9
665 graft-versus-host disease 9.9
666 leptin deficiency or dysfunction 9.9
667 leptin receptor deficiency 9.9
668 facial dysmorphism, immunodeficiency, livedo, and short stature 9.9
669 leukemia, acute lymphoblastic 3 9.9
670 metabolic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 9.9
671 spastic paraplegia, intellectual disability, nystagmus, and obesity 9.9
672 neuronal ceroid-lipofuscinoses 9.9
673 polyomavirus-associated nephropathy 9.9
674 congenital hypothyroidism 9.9
675 weill-marchesani syndrome 9.9
676 second-degree atrioventricular block 9.9
677 lymphoma 9.9
678 scoliosis 9.9
679 dental abscess 9.9
680 anterior segment dysgenesis 9.9
681 syndromic x-linked intellectual disability cabezas type 9.9
682 polycystic kidney disease 9.9
683 desmoid tumor 9.9
684 chronic eosinophilic leukemia 9.9
685 b-lymphoblastic leukemia/lymphoma 9.9
686 mild cognitive impairment 9.9
687 graves ophthalmopathy 9.9
688 hypogonadotropic hypogonadism 9.9
689 progressive myoclonus epilepsy 4 9.9
690 trichothiodystrophy 9.9
691 nonphotosensitive trichothiodystrophy 9.9
692 hyperlucent lung 9.9
693 caplan's syndrome 9.9
694 common cold 9.9
695 disseminated intravascular coagulation 9.9
696 vitamin k deficiency bleeding 9.9
697 lyme disease 9.9
698 mucopolysaccharidosis iii 9.9
699 thyroid crisis 9.9
700 choreatic disease 9.9
701 uveitis 9.9
702 pulmonary sarcoidosis 9.9
703 osteopetrosis 9.9
704 hyperparathyroidism 9.9
705 toxic shock syndrome 9.9
706 adult-onset still's disease 9.9
707 axenfeld-rieger syndrome 9.9
708 pneumothorax 9.9
709 malignant fibrous histiocytoma 9.9
710 spondylosis 9.9
711 arteriosclerosis 9.9
712 iron metabolism disease 9.9
713 acromegaly 9.9
714 angiodysplasia 9.9
715 hematologic cancer 9.9
716 bilirubin metabolic disorder 9.9
717 churg-strauss syndrome 9.9
718 gallbladder cancer 9.9
719 bipolar disorder 9.9
720 plague 9.9
721 turner syndrome 9.9
722 tricuspid valve stenosis 9.9
723 fibrous histiocytoma 9.9
724 cutaneous fibrous histiocytoma 9.9
725 calciphylaxis 9.9
726 epidermolysis bullosa dystrophica 9.9
727 bronchitis 9.9
728 juvenile rheumatoid arthritis 9.9
729 b-cell lymphoma 9.9
730 gastrointestinal system disease 9.9
731 polyhydramnios 9.9
732 lung disease 9.9
733 chronic fatigue syndrome 9.9
734 ulcerative colitis 9.9
735 exophthalmos 9.9
736 bronchiectasis 9.9
737 polyarteritis nodosa 9.9
738 alopecia 9.9
739 aberrant subclavian artery 9.9
740 banti's syndrome 9.9
741 cardiac rupture 9.9
742 cytokine deficiency 9.9
743 lymphangiectasis 9.9
744 oto-palatal-digital syndrome 9.9
745 partial atrioventricular canal 9.9
746 progressive encephalomyelitis with rigidity and myoclonus 9.9
747 retroperitoneal fibrosis 9.9
748 rheumatoid vasculitis 9.9
749 ring chromosome 1 9.9
750 ring chromosome 17 9.9
751 ring chromosome 2 9.9
752 ring chromosome 3 9.9
753 ring chromosome 4 9.9
754 single ventricular heart 9.9
755 systemic onset juvenile idiopathic arthritis 9.9
756 mucopolysaccharidoses 9.9
757 b-cell non-hodgkin lymphoma 9.9
758 functional neutrophil defect 9.9
759 systemic autoimmune disease 9.9
760 inflammatory myopathy with abundant macrophages 9.9
761 virus-associated trichodysplasia spinulosa 9.9
762 neonatal marfan syndrome 9.9
763 tropical endomyocardial fibrosis 9.9
764 peripheral pulmonary stenosis 9.9
765 cervical aortic arch 9.9
766 atrial septal aneurysm 9.9
767 accessory mitral valve tissue 9.9
768 nervous system disease 9.9 REN MME MIR423 F2 CRP ALB
769 body mass index quantitative trait locus 11 9.8 REN NR3C2 MIR423 CRP ALB ACE
770 intrinsic cardiomyopathy 9.7 TNNT2 TNNI3 REN NPPB NPPA MYH6
771 extrinsic cardiomyopathy 9.7 TNNT2 TNNT1 TNNI3 REN NPPB MYH6
772 pulmonary artery disease 9.7 TNNT2 TNNT1 TNNI3 REN NPPB F2
773 pericardium disease 9.7 TNNT2 TNNT1 TNNI3 REN NPPB F2
774 heart conduction disease 8.9 TNNT2 TNNT1 TNNI3 TBX5 REN NR3C2

Graphical network of the top 20 diseases related to Mitral Valve Insufficiency:

Diseases related to Mitral Valve Insufficiency

Symptoms & Phenotypes for Mitral Valve Insufficiency

MGI Mouse Phenotypes related to Mitral Valve Insufficiency:

45 (showing 3, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 10 ALB F2 FBN1 MYBPC3 MYH11 MYH6
2 homeostasis/metabolism MP:0005376 9.8 ACE ALB CRP F2 FBN1 MME
3 cardiovascular system MP:0005385 9.5 ACE ALB CRP F2 FBN1 MYBPC3

Drugs & Therapeutics for Mitral Valve Insufficiency

Drugs for Mitral Valve Insufficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 106, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Ranolazine Approved, Investigational Phase 4 142387-99-3, 95635-55-5 56959
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
Candesartan cilexetil Approved Phase 4 145040-37-5
Tetracosactide Approved Phase 4 16960-16-0 16133802 16129617
Etomidate Approved Phase 4 33125-97-2 667484
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 3640 5754
Hydrocortisone succinate Approved Phase 4 2203-97-6 3643
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
Hydralazine Approved Phase 4 86-54-4 3637
Candesartan Experimental Phase 4 139481-59-7 2541
protease inhibitors Phase 4
14 HIV Protease Inhibitors Phase 4
15 Diuretics, Potassium Sparing Phase 4
16 Sodium Channel Blockers Phase 4
17 Serine Proteinase Inhibitors Phase 4
18 Antithrombins Phase 4
19 Antithrombin III Phase 4
20 Anticoagulants Phase 4
21 Antioxidants Phase 4
22 Omega 3 Fatty Acid Phase 4
Angiotensinogen Phase 4 16133225
24 Angiotensin II Type 1 Receptor Blockers Phase 4
25 Giapreza Phase 4
26 Vasoconstrictor Agents Phase 4
27 Hormones Phase 4
28 Hormone Antagonists Phase 4
29 Anti-Inflammatory Agents Phase 4
30 Anesthetics, Intravenous Phase 4
31 Anesthetics, General Phase 4
32 Hydrocortisone 17-butyrate 21-propionate Phase 4
33 Hypnotics and Sedatives Phase 4
34 Sacubitril and valsartan sodium hydrate drug combination Phase 4
35 Mineralocorticoids Phase 4
36 Mineralocorticoid Receptor Antagonists Phase 4
37 Anesthetics Phase 4
Serine Investigational, Nutraceutical Phase 4 56-45-1 5951
Metoprolol Approved, Investigational Phase 2, Phase 3 37350-58-6, 51384-51-1 4171
Bupivacaine Approved, Investigational Phase 3 2180-92-9, 38396-39-3 2474
Milrinone Approved Phase 3 78415-72-2 4197
Ertugliflozin Approved, Investigational Phase 3 1210344-57-2 75075340 44814423
Enalaprilat Approved Phase 3 76420-72-9 6917719 5462501
Enalapril Approved, Vet_approved Phase 3 75847-73-3 40466924 5388962 5362032
Nifedipine Approved Phase 3 21829-25-4 4485
46 Adrenergic beta-Antagonists Phase 2, Phase 3
47 Antihypertensive Agents Phase 2, Phase 3
48 Pharmaceutical Solutions Phase 3
49 Cardiotonic Agents Phase 3
50 Protective Agents Phase 3
51 Neurotransmitter Agents Phase 2, Phase 3
52 Platelet Aggregation Inhibitors Phase 3
53 Sympatholytics Phase 2, Phase 3
54 Anti-Arrhythmia Agents Phase 2, Phase 3
55 Adrenergic beta-1 Receptor Antagonists Phase 2, Phase 3
56 Anesthetics, Local Phase 3
57 Phosphodiesterase Inhibitors Phase 3
58 Phosphodiesterase 3 Inhibitors Phase 3
59 Sodium-Glucose Transporter 2 Inhibitors Phase 3
60 Hypoglycemic Agents Phase 3
61 Adrenergic Agents Phase 3
62 diuretics Phase 3
63 Adrenergic Antagonists Phase 3
64 Vasodilator Agents Phase 3
Lidocaine Approved, Vet_approved Phase 2 137-58-6 3676
Racephedrine Approved, Experimental Phase 1, Phase 2 299-42-3, 90-82-4, 90-81-3 5032 9294 7028
Oxymetazoline Approved, Investigational Phase 1, Phase 2 1491-59-4 4636
Phenylephrine Approved Phase 1, Phase 2 59-42-7 6041
Cyproheptadine Approved Phase 2 129-03-3 2913
Histamine Approved, Investigational Phase 2 51-45-6 774
71 Complement System Proteins Phase 2
72 Mydriatics Phase 1, Phase 2
73 Adrenergic alpha-Agonists Phase 1, Phase 2
74 Adrenergic Agonists Phase 1, Phase 2
75 Nasal Decongestants Phase 1, Phase 2
76 Sympathomimetics Phase 1, Phase 2
77 Respiratory System Agents Phase 1, Phase 2
78 Dermatologic Agents Phase 2
79 Gastrointestinal Agents Phase 2
Histamine phosphate Phase 2 51-74-1 134614
81 Histamine H1 Antagonists Phase 2
82 Histamine Antagonists Phase 2
83 Anti-Allergic Agents Phase 2
Serotonin Investigational, Nutraceutical Phase 2 50-67-9 5202
Ethanol Approved 64-17-5 702
Nutmeg Approved
Spironolactone Approved 1952-01-7, 52-01-7 5833
Acetylsalicylic acid Approved, Vet_approved 50-78-2 2244
Clopidogrel Approved 120202-66-6, 113665-84-2 60606
Dobutamine Approved 34368-04-2 36811
Racepinephrine Approved, Vet_approved 51-43-4, 329-65-7 838 5816
Caffeine Approved 58-08-2 2519
Ropivacaine Approved 84057-95-4 71273 175805
94 Kava Approved, Investigational, Nutraceutical 9000-38-8
95 Cardioplegic Solutions
96 Mace
97 Cyclooxygenase Inhibitors
98 Fibrinolytic Agents
99 Purinergic P2Y Receptor Antagonists
100 Antirheumatic Agents
101 Antipyretics
102 Anti-Inflammatory Agents, Non-Steroidal
103 Analgesics, Non-Narcotic
104 Analgesics
105 Natriuretic Peptide, Brain
106 Epinephryl borate

Interventional clinical trials:

(showing 326, show less)
# Name Status NCT ID Phase Drugs
1 Interventional Strategy to Abrogate Mitral Regurgitation Using the MitraClip System in High-Risk Patients Considered Unsuitable for Surgery (ISAR-CLIP) Unknown status NCT01431222 Phase 4
2 Ranolazine Effects on Ischemic Mitral Regurgitation Severity in Patients With Cardiac Resynchronization Therapy Unknown status NCT01979965 Phase 4 Ranolazine (Active drug);Placebo
3 The Effect of Different Surgical Methods in the Treatment of Patients With Ischemic Mitral Regurgitation and Assess the Dynamics of Heart Failure and the Effectiveness of Surgical Treatment of Mitral Valve. Unknown status NCT01368575 Phase 4
4 (MitraClip in Non-Responders to Cardiac Resynchronization Therapy) Unknown status NCT02592889 Phase 4
5 Effects of the Administration Of Antithrombin on the Coagulation Status and on the Inflammatory Response in Patients With Low Plasmatic Levels of Antithrombin After Cardiac Surgery Unknown status NCT01201070 Phase 4 antithrombin III
6 Mitigating Cardiac Inflammation and Oxidative Stress in Atrial Myocardium Via Short-term Lovaza Treatment Prior to Surgery Unknown status NCT01046604 Phase 4 Lovaza group
7 Multicenter, Randomized, Double-blind, Active-controlled Study to Assess the Efficacy of LCZ696 Compared to Valsartan on Reduction of Mitral Regurgitation in Patients With Left Ventricular Dysfunction and Secondary Functional Mitral Regurgitation of Stage B and C Completed NCT02687932 Phase 4 LCZ696;Valsartan
8 Beta Blockade in Mitral Regurgitation Completed NCT00166400 Phase 4 metoprolol succinate
9 Angiotensin-II Blockade in Mitral Regurgitation Completed NCT00587470 Phase 4 Candesartan;atacand;Placebo
10 Colvin-Galloway Future® Annuloplasty Ring/Band Clinical Trial: Interventional Multi-center Prospective Clinical Outcome Study Completed NCT01074671 Phase 4
11 Study of Paravertebral Block for Cardiac Surgery Completed NCT02180893 Phase 4
12 Effect of an Anesthetic Induction Dose of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac Surgery Completed NCT00415701 Phase 4 Etomidate;Propofol;Hydrocortisone;NaCl 0.9%
13 Clinical and Ultramicroscopic Myocardial Randomized Study of On-Pump Beating Heart Mitral Valve Replacement Completed NCT01641614 Phase 4
14 The Prognostic Impact of Using High-dose Hydralazine in Severe Systolic Heart Failure With Hemodynamically Significant Mitral Regurgitation Recruiting NCT04217135 Phase 4 evidence-based medications vs. high-dose hydralazine + evidence-based medications
15 Strategy To Optimize PeriproCeduraL AnticOagulation in Structural Transseptal Interventions Enrolling by invitation NCT05305612 Phase 4
16 High and Intermediate Risk Degenerative Mitral Regurgitation Treatment: A Randomized Controlled Trial Comparing MitraClip® to Surgical Therapy Terminated NCT02534155 Phase 4
17 Multicentre Randomized Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation. Unknown status NCT01920698 Phase 3
18 Randomized Evaluation of Mitral Annuloplasty During Coronary Artery Bypass Grafting for Moderate Functional Ischaemic Mitral Regurgitation. Completed NCT00413998 Phase 3
19 Molecular Mechanisms of Volume Overload-Aim 1(SCCOR in Cardiac Dysfunction and Disease) Completed NCT01052428 Phase 2, Phase 3 metoprolol succinate (Toprol XL);Placebo
20 Comparative Effects of Brief Inhaled Milrinone Versus Intravenous Milrinone on Pulmonary Arterial Pressure in Patients Undergoing Mitral Valve Surgery Completed NCT01621971 Phase 3 inhaled milrinone;intravenous milrinone
21 Clinical Investigation Of The Sorin 3D Annuloplasty Ring For Mitral Repair Completed NCT00567853 Phase 3
22 Postoperative Analgesia After Cardiac Surgery - A Double-Blind, Prospective and Randomized Comparison of Wound Infiltration With Liposomal Bupivacaine and Bupivacaine Hydrochloride Completed NCT03270514 Phase 3 Exparel Injectable Product;Bupivacaine Hydrochloride
23 Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Assess the Efficacy of Ertugliflozin on Reduction of Mitral Regurgitation in Patients With Functional Mitral Regurgitation Secondary to Left Ventricular Dysfunction Recruiting NCT04231331 Phase 3 Ertugliflozin;Placebo
24 The Safety and Effectiveness of the SAPIEN 3 and SAPIEN 3 Ultra Valve in Patients With Symptomatic Severe Calcific Mitral Valve Disease With Severe Mitral Annular Calcification Who Are Not Candidates for Standard Mitral Valve Surgery. Recruiting NCT04408430 Phase 2, Phase 3
25 Safety and Efficacy of Percutaneous Transvenous Mitral Annuloplasty System to Reduce Mitral Valve Regurgitation in Patients With Heart Failure Suspended NCT00815386 Phase 2, Phase 3
26 Trial of ACE Inhibition in Children With Mitral Regurgitation After Repair of AVSD Terminated NCT00113698 Phase 3 Enalapril
27 Surgery Versus Medical Treatment Alone for Patients With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure: SMMART-HF Terminated NCT00608140 Phase 3 Optimal medical therapy (OMT)
28 Dynamic Annuloplasty System With Activation for the Treatment of Mitral Regurgitation Unknown status NCT00833014 Phase 2
29 Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation Completed NCT00807040 Phase 2
30 The Study for Atrial Functional Mitral Regurgitation Response In Mitral Loop Cerclage Annuloplasty (AFRICA Study): Multi-center, Open Label, Single Arm, Feasibility Test Completed NCT03453853 Phase 1, Phase 2
31 An Open-Label, Single-Arm Pilot Study of the Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Device Used to Reduce Mitral Regurgitation Completed NCT00572091 Phase 1, Phase 2
32 Comparison of Erector Spinae Plane Block and Pecto-Intercostal Facial Plane Block For Enhanced Recovery After Sternotomy in Adult Cardiac Surgery Completed NCT05475561 Phase 2 Bupivacain
33 A Study of the Evalve Cardiovascular Valve Repair System Endovascular Valve Edge-to-Edge REpair STudy (EVEREST I). Completed NCT00209339 Phase 1, Phase 2
34 Surgical Ablation Versus No Surgical Ablation for Patients With Persistent or Longstanding Persistent Atrial Fibrillation (AF) Undergoing Mitral Valve Surgery Completed NCT00903370 Phase 2
35 Safety and Efficacy of TP10, a Complement Inhibitor, in Adult Women Undergoing Cardiopulmonary Bypass Surgery Completed NCT00082121 Phase 2 TP10
36 Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve (RESTOR-MV) Completed NCT00120276 Phase 2
37 Evaluating the Severity of Mitral Regurgitation Using Phenylephrine During Transesophageal Echocardiography Recruiting NCT04500899 Phase 1, Phase 2 Mydfrin
38 Blocking the Effects of Serotonin to Prevent Ischemic Mitral Regurgitation: a Randomized Trial (CYPRO-MR) Not yet recruiting NCT05469165 Phase 2 Cyproheptadine 4 Mg Oral Tablet
39 A Multi-center Study of the Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty System to Reduce Mitral Valve Regurgitation in Patients With Heart Failure Suspended NCT00787293 Phase 2
40 V-Chordal Adjustable System for Chordal Replacement in Mitral Valve Insufficiency Due to Leaflet Prolapse Terminated NCT01415947 Phase 2
41 Mitral Valve Reconstruction in Patients With Chronic Heart Failure and Secondary Mitral Insufficiency: Identification of Predictors for a Successful Therapy Terminated NCT00348829 Phase 2
42 The RELIEF Trial: REduction or eLimination of mItral rEgurgitation in Degenerative or Functional Mitral Regurgitation With the CardiAQ-Edwards™ Transcatheter Mitral Valve Withdrawn NCT02722551 Phase 1, Phase 2
43 Medical Versus Surgical Management of Patients With Moderate Mitral Regurgitation Following Percutaneous Coronary Intervention for Myocardial Infarction: A Pilot Prospective Randomized Trial Withdrawn NCT01156441 Phase 1, Phase 2
44 Prospective.Randomized, Blinded, Crossover Chronic IDE Study of the Effects of Pacing on Mitral Regurgitation in Patients Without Standard Indications for Cardiac Resynchronization Therapy Unknown status NCT01242397 Phase 1
45 A Novel Adjustable Neochordae Technique in Mitral Valve Repair Unknown status NCT04299334 Phase 1
46 Valvular and Ventricular Improvement Via iCoapsys Delivery (VIVID) Feasibility Study Unknown status NCT00512005 Phase 1
47 An Open-Label, Single-Arm Feasibility Study of the Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty (PTMA) Device Used to Reduce Mitral Regurgitation. Completed NCT00568230 Phase 1
48 A Single-Center, Open-Label, Single-Arm Pilot Study of the Safety and Efficacy of the Percutaneous Transvenous Mitral Annuloplasty Implantable Device Used to Reduce Mitral Valve Regurgitation. Completed NCT00571610 Phase 1
49 TVMR With the Innovalve System Trial - Early Feasibility Study Not yet recruiting NCT04919980 Phase 1
50 Beta-Blockade in Chronic Mitral Regurgitation: Moving From the Laboratory Experiment to Clinical Investigation Terminated NCT00700947 Phase 1 Beta-blocker therapy (TOPROL-XL® )
51 The Papillary Muscle Approximation Provide Stability of Mitral Valve Repair for Ischemic Mitral Regurgitation Unknown status NCT03038204
52 POsition of Leads in Advanced heaRt Failure: the POLAR Study - A 6 Month, Observational, Mult-centered, Blinded, Randomized Study to Determine if Lead Positioning in the Lateral Wall of LV in Patients Meeting Criteria for CRT Plays a Role in Determining Myocardial Function and Affect the Severity of Mitral Regurgitation Unknown status NCT01515761
53 The Randomly Controlled Trial of Optimal Surgical Method for CAD Patients Combined Moderate Functional Ischemic Mitral Regurgitation Unknown status NCT03525041
54 Use of Percutaneous Mitral Leaflet Approach for Severe Mitral Regurgitation in Cardiogenic Shock: Results From a Multicenter Observational Italian Experience (the Mitra-Shock Study). Unknown status NCT04399499
55 Invasive Hemodynamic Stress Test in Symptomatic and Asymptomatic Mitral Regurgitation Unknown status NCT02961647
56 Evaluation of Remote Monitoring in Patients With Functional Mitral Regurgitation Undergoing Transcatheter Mitral Valve Edge-to-edge Repair With the Mitraclip System Unknown status NCT02698150
57 Moderate Mitral Regurgitation in CABG Patients Unknown status NCT00613548
58 Unmasking the Dynamic Component in Functional Mitral Regurgitation in Chronic Heart Failure Unknown status NCT03315429
59 A Prospective, Multicenter, Single Group Assignment Study for Evaluating the Safety and Effectiveness of MitralStitch Mitral Valve Repair System in Patients With Moderate to Severe and Severe Mitral Regurgitation. Unknown status NCT04080362
60 Should we Repair Ischemic Mitral Regurgitation? Unknown status NCT00443365
61 MitraClip® for the Treatment of Recurrent Severe Mitral Regurgitation After Surgical Mitral Valve Repair Unknown status NCT02853955
62 Predictors of Postoperative Left Ventricular Function in Patients Undergoing Mitral Valve Repair for Severe Degenerative Mitral Regurgitation Unknown status NCT01519050
63 Primary Mitral Regurgitation Reverse Remodeling Unknown status NCT04067635
64 Patient Specific Mitral Valve Modeling for Surgical Planning and Training Unknown status NCT03609931
65 Evaluation of the Minimally Invasive VenTouch™ System in the Treatment of Functional Mitral Valve Regurgitation (FMR): First-In-Man Continuation Study Unknown status NCT02671799
66 Morphodynamic Study of Left Ventricular Remodeling With Possible Mechanisms for Pharmacologic Therapy: Assessment by Real-time 3-dimensional Echocardiography and 2-dimensional Speck Tracking Imaging. Unknown status NCT00745680
67 GIse Registry Of Transcatheter Treatment of Mitral Valve regurgitaTiOn (GIOTTO) Unknown status NCT03521921
68 Evaluation of Safety and Efficacy of the Basal Annuloplasty of the Cardia Externally (BACE™) [Basal Annuloplasty of the Cardia Externally] Device in the Treatment of Functional Mitral Valve Regurgitation [FMR] Unknown status NCT02701972
69 Effect of MitraClip on Reverse Cardiac Remodeling Assessed by CMR and Echocardiography: The MITRA-REVERSE Study A Prospective Multicenter Study Unknown status NCT02924363
70 Expiratory Flow Limitation and Mechanical Ventilation During Cardiopulmonary Bypass in Cardiac Surgery Unknown status NCT02633423
71 EValuation of Outcomes of Transcatheter Mitral Valve Repair for the Treatment of Low Ejection Fraction and Moderate Functional Mitral ValvE Regurgitation In Heart Failure Unknown status NCT03705312
72 International Multicenter Registry of Patients With Concomitant Aortic and Mitral Valve Disease Undergoing Transcatheter Aortic Valve Implantation - The Aortic+Mitral TRAnsCatheter (AMTRAC) Valve Registry Unknown status NCT04031274
73 MitraBridge Registry Unknown status NCT04293575
74 To Evaluate the Effectiveness and Safety of MitralStitch Mitral Valve Repair System - a Clinical Application of New Technology Unknown status NCT04061837
75 Comparative Gene Expression Profiles in Patients With Permanent Atrial Fibrillation and Normal Sinus Rhythm Unknown status NCT00970034
76 Prospective Evaluation of MRI as a Predictor of Outcomes in Patients Undergoing Mitral Valve Surgery: MRI-MVS Study Unknown status NCT03012178
77 Magnetic Resonance Neurological Evaluation After Right Mini-thoracotomy Mitral Valve Surgery: Trans-thoracic Versus Endoaortic Clamp Unknown status NCT02818166
78 First in Human Safety Study of the Synecor Conveyor System Used for Delivery of a Minimally Invasive Mitral Valve Unknown status NCT03893578
79 The Effect of Posterior Annulus Elevation Technique in Reducing Residual Regurgitation During Mitral Valve Repair in Children Unknown status NCT04518709
80 A Multicenter, Randomized, Controlled Study to Assess Mitral vAlve reconsTrucTion for advancEd Insufficiency of Functional or iscHemic ORigiN Unknown status NCT02371512
81 Clinical Evaluation and Geriatric Assessment in Elderly Patients Before and After Percutaneous Aortic Valve Implantation (TAVI) or MitraClip Positioning Unknown status NCT03145376
82 A Feasibility Study of the Mitralign Annuloplasty System for the Treatment of Chronic Functional Mitral Valve Regurgitation Unknown status NCT01740583
83 Individualized Surgical Repair for Congenital Mitral Insufficiency in Infants and Children Unknown status NCT03567668
84 Mitral Valve Replacement With the MValve Dock and A Percutaneous Transcatheter Heart Valve Unknown status NCT02719912
85 Exercise-induced in Secondary Mitral Regurgitation: Analysis of Echocardiographic Parameters at Rest Predicting the Onset of Significant Exercise-induced Mitral Regurgitation Completed NCT03978676
86 A Study of Percutaneous Repair of Functional Mitral Regurgitation Using the Ancora Heart, Inc. AccuCinch® Ventricular Repair System - The CINCH-2 Study Completed NCT00800046
87 The MitraClip Russia Trial: A Prospective, Single-Center, Single-Arm Clinical Evaluation of the MitraClip System for the Treatment of Mitral Regurgitation Completed NCT04350372
88 Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation Completed NCT01172184
89 Annular Reshaping of the Mitral Valve for Patients With Mitral Regurgitation Using the Millipede IRIS System Completed NCT02607527
90 Degenerative Mitral Regurgitation in Intermediate Risk Patients 65 or Older: Exercise Echocardiogram and HRQOL Post Surgery Preliminary Analysis Completed NCT02604745
91 A Retrospective Multicenter Canadian Registry of Patients With Mitral Regurgitation Undergoing Percutaneous Mitral Valve Repair With MitraClip Completed NCT03592043
92 Functional Mitral Regurgitation in STICH Completed NCT00224809 Angiotensin-Converting Enzyme Inhibitors;Angiotensin Receptor Blockers;Spironolactone;Aspirin;Clopidogrel
93 Association of Global Longitudinal Strain and Global Constructive Work With Cardiac Performance and Clinical Outcome One Year After MitraClip Implantation in Functional Mitral Regurgitation Completed NCT04218578
94 Transcatheter Mitral Valvuloplasty for Severe Mitral Regurgitation Pilot Study Completed NCT04351984
95 Clinical Protocol - A Feasibility Study Using the AccuCinch® System in the Left Ventricular Reshaping of the Mitral Apparatus to Reduce Functional Mitral Regurgitation and Improve Left Ventricular Function Completed NCT02153892
96 Incidence of Significant Mitral Regurgitation in Patients Presenting With Acute Heart Failure: Journey to Tertiary Centre Completed NCT02728739
97 New Techniques to Evaluate Mitral Regurgitation Completed NCT01063322
98 Investigation of Myocardial Contractile Reserve by Dobutamine Stress Transesophageal Echocardiography in Aortic and Mitral Regurgitation Completed NCT00001314
99 Minimally Invasive or Conventional Edge-To-Edge Repair for Severe Mitral Regurgitation Due to Bileaflet Prolapse in Barlow's Disease: Does the Surgical Approach Have an Impact on the Long-term Results? Completed NCT04002648
100 Safety and Performance Study of the Harpoon Medical Transapical Suturing Device (TSD-5) in Subjects With Degenerative Mitral Regurgitation - EFS/CE Mark Study for the Harpoon Medical Device in Poland Completed NCT02771275
101 The Study to Define the Unique Molecular Mechanisms of Mitral Regurgitation in Order to Find New Targeted Therapy to Attenuate the Remodeling and Delay the Need for Surgery and Improve Surgical Outcomes. Completed NCT01052532
102 Repair of Ischemic Mitral Regurgitation: Comparison Between Flexible and Rigid Annuloplasty Rings Completed NCT00491452
103 Surgical Interventions for Moderate Ischemic Mitral Regurgitation Completed NCT00806988
104 Biomarkers in Aortic Stenosis, Hypertrophic Cardiomyopathy, Mitral Regurgitation, Aortic Regurgitation, Prosthetic Heart Valve Dysfunction, and Tricuspid Regurgitation From Pacemaker Leads Study Completed NCT01334801
105 Surgical Correction of Moderate Ischemic Mitral Regurgitation Completed NCT00394797
106 A Study of Percutaneous Left Ventricular Reshaping of Mitral Apparatus to Reduce Functional Mitral Regurgitation and Improve LV Function Using the Accucinch® System Completed NCT01899573
107 Cardiopulmonary Exercise Testing in Severe Mitral Regurgitation - a Single Center, Observational Echocardiographic Study Completed NCT03154034
108 A Prospective Observational Study Examining the Role of Myocardial Fibrosis in Outcome Following Mitral Valve Repair in Degenerative Mitral Regurgitation. Completed NCT02355418
109 The REDUCE FMR Trial: Safety and Efficacy of the CARILLON Mitral Contour System® in Reducing Functional Mitral Regurgitation (FMR) Associated With Heart Failure Completed NCT02325830
110 Safety and Performance Study of the NeoChord Suturing Device in Subjects With Degenerative Mitral Valve Disease; Diagnosed With Severe Mitral Regurgitation Completed NCT01777815
111 A Prospective, Multi-Center, Single-Arm Clinical Evaluation of the AVJ-514 System for the Treatment of Symptomatic Chronic Severe Mitral Regurgitation Completed NCT02520310
112 The Effect of Percutaneous Superior Venae Cava Cannulation Clamping on Cerebral Near Infrared Spectroscopy During Minimally Invasive Mitral Valve Surgery Completed NCT01166841
113 Long-term Outcome Following Transcatheter Para-Valvular Leak Closures: An International Retrospective Multicenter Registry Completed NCT05117359
114 European Registry of MitraClip in Acute Myocardial Infarction Completed NCT03107455
115 AMEND I Study - for the Valcare Medical AMEND TM Mitral Valve Repair System Completed NCT02602613
116 Safety and Feasibility of Deep Sedation Instead of General Anaesthesia in Percutaneous Mitral Valve Repair Using the MitraClip® System Completed NCT02023762
117 Silent sTROke duriNG MitraClip Implantation - STRONG-MitraClip Completed NCT03104556
118 Does Acute Normovolemic Hemodilution Affect Intraoperative Value of Serum-creatinine Concentration in Patients Undergoing Cardiac Surgery? Completed NCT02831270 hydroxyethyl starch (HES 130/0.6)
119 Pivotal Study: A Study of the Evalve Cardiovascular Valve Repair System - Endovascular Valve Edge-to-Edge REpair STudy (EVERESTIIRCT) Completed NCT00209274
120 Mitral Valve Repair Using Flexible Bands Versus Complete Rings in Patients With Degenerative Mitral Valve Disease: a Prospective, Randomized Study Completed NCT03278574
121 Evaluation of the 5-Year Safety and Performance of the Medtentia Annuloplasty Ring in Adults - Follow-Up to Clinical Investigation 2010-040 Completed NCT04161079
122 Percutaneous Mitral Valve Intervention: Predicting Improvements in Left Ventricular Performance Completed NCT04156295
123 Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair Completed NCT03993938
124 Validation Study Comparing the Cardiac Output Pulmonary Arterial Catheter (Swan Ganz) to the FloWave™ 1000 Device Completed NCT00665301
125 Identifying the Ideal Parameter of the Cardiopulmonary Exercise Test to Distinguish Between the Cardiovascular and Respiratory Components of Functional Limitation and to Detect Relevant Physiological Changes in Function Completed NCT01162083
126 A Contemporary, Prospective Study Evaluating Real-world Experience of Performance and Safety for the Next Generation of MitraClip® Devices (EXPAND) Completed NCT03502811
127 MitraClip NT System Post -Marketing Surveillance Study Completed NCT03500692
128 Phono- and Electrocardiogram Assisted Detection of Valvular Disease Completed NCT03458806
129 A Study of the Evalve® Cardiovascular Valve Repair (MitraClip®) System Endovascular Valve Edge-to-Edge REpair STudy (EVEREST II) EVEREST II High Risk Registry Completed NCT01940120
130 Cardioband Adjustable Annuloplasty System For Transcatheter Repair of Mitral Valve Regurgitation Completed NCT01841554
131 Cephea Mitral Valve and Transseptal Delivery System FIH Completed NCT03988946
132 A Continued Access Registry of the Evalve® MitraClip® System: EVEREST II Real World Expanded Multicenter Study of the MitraClip System (REALISM) Completed NCT01931956
133 Mitralign Percutaneous Annuloplasty First in Man (FIM) Study Completed NCT01852149
134 An Acute Evaluation of Anatomical and Geometric Changes Using the Bladder on a Stick System (BOSS) Completed NCT03228381
135 Impact of Acute Normovolemic Hemodilution on Whole Blood Coagulation Profile During Post-cardiopulmonary Bypass in Cardiac Surgery: Rotational Thromboelastometry Study Completed NCT02502448 hydroxyethyl starch (HES 130/0.6)
136 MITRAFIT Cardinal Adjustable Mitral Repair Follow-up International Postmarketing Surveillance (PMS) Completed NCT01617720
137 The Right Ventricular Pulmonary Circulation Continuum in Mitral Valve Disease Completed NCT03155373
138 The Study on Safety and Feasibility of Mitral Loop Cerclage(MLC) Annuloplasty Procedure With Investigational Medical Device (MLC-B-45-75-R and Other 11 Models) : Single-centre, Open Label, Single Arm, Feasibility Test Completed NCT02471664
139 Valtech Cardinal Adjustable Semi-Rigid Annuloplasty Ring System For Treatment of Mitral Valve Regurgitation in Open Surgical Repair Completed NCT01137734
140 Multicenter International Trial Ring AnnulopLasty Completed NCT00727012
141 Quantitative Analysis of Catheter-based Interventional Therapies for Treating Valve Insufficiency by Using 3D Echocardiography. Completed NCT01966146
142 Post-Approval Study Protocol of the St. Jude Medical Biocor and Biocor Supra Valves Completed NCT00636987
143 EASE MITRAL Expertise-based Assessment Study on Clinical Efficacy of Profile 3D in MITRAL Valve Annuloplasty Completed NCT01112566
144 Post-Market Surveillance Registry for the NeoChord DS1000 Completed NCT01784055
145 SEP-study; The Assessment of Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Organic Mitral Valve Regurgitation Completed NCT02371863
146 Physical and Functional Recovery From Cardiac Surgery in Hospitalized Patients: A Feasibility Pilot Study Completed NCT02375282
147 Phonokardiographie Bei Erwachsenen Completed NCT03600051
148 Evaluation of Mitral and Tricuspid Regurgitation: Cardiovascular Magnetic Resonance Imaging Versus Echocardiographic Doppler Color Flow Mapping of the Vena Contracta Completed NCT01504880
149 MERIT Study - Mistral Percutaneous Mitral Valve Repair FIM Study Completed NCT02948231
150 OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety Evaluation (OPTIMISE) Completed NCT03842397
151 Coronary and Structural Interventions Ulm - Transcatheter Mitral Valve Repair (CSI-Ulm-TMVR) Completed NCT03104660
152 Mitral Adjustable Annuloplasty Ring Feasibility and Safety Study (MAARS) for Treatment of Patients With Mitral Valve Regurgitation in Open Surgical Repair Completed NCT00554151
153 Mitral Valve Regurgitation Quantification From 3D Color Doppler Ultrasound - Standard of Care Data Collection Completed NCT03286088
154 Compare Results of Mitral Valve Replacement or Repair in the Surgical Treatment of Obstructive Hypertrophic Cardiomyopathy With Severe Mitral Insufficiency. Completed NCT02054221
155 Comparison of Blood Cardioplegia and Custodiol on Patients Operated for Significant Mitral Valve Innsufisiens. An Prospective, Randomized Two-center Study. Completed NCT01941459
156 Epidemiology and Long-term Prognosis of Patients With Valvular Heart Diseases (BIA-WAD Study) Completed NCT04527367
157 Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation Recruiting NCT03433274
158 Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP IID/IIF): A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Evaluate the Safety and Effectiveness of Transcatheter Mitral Valve Repair With the Edwards PASCAL Transcatheter Valve Repair System Compared to Abbott MitraClip in Patients With Mitral Regurgitation Recruiting NCT03706833
159 Transcatheter Repair of Mitral Regurgitation With Edwards PASCAL Transcatheter Valve Repair System: A European Prospective, Multicenter Post Market Clinical Follow-Up (PMCF) Recruiting NCT04430075
160 A Prospective Randomized Trial Comparing the Surgical Treatment of Ischemic Mitral Regurgitation Versus Percutaneous Mitral Repair Followed by Surgical Revascularization Recruiting NCT04822675
161 A Prospective, Multicenter, Objective Performance Criteria Study to Evaluate the Safety and Effectiveness of Dragonfly Transcatheter Mitral Valve Repair System for the Treatment of Functional Mitral Regurgitation (FMR) Subjects. Recruiting NCT04733404
162 Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Functional Mitral Regurgitation (EXPLORE FMR) Recruiting NCT04666467
163 Coronary Physiology Peri-Transcatheter Left-sided Valvular Interventions in Patients With Severe Aortic Stenosis or Mitral Regurgitation Recruiting NCT05374733
164 Transcatheter Repair of Mitral Regurgitation With Cardioband System Post Market Study:A European Prospective, Multicenter Study to Assess Transcatheter Mitral Valve Repair With Edwards Cardioband System in Patients With Symptomatic MR Recruiting NCT03600688
165 Multi-center Trial of Transcatheter Edge-to-edge Mitral Valve Repair With ValveClamp System in High Risk Patients With Degerative Mitral Regurgitation Recruiting NCT03869164
166 A Prospective, Multi-Center, Single-Arm, Post Market Study of the MitraClip System for the Treatment of Symptomatic Mitral Regurgitation in China Recruiting NCT04259411
167 Multicentre and Randomized Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery Recruiting NCT03271762
168 European Feasibility Study of High Surgical Risk Patients With Severe Mitral Regurgitation Treated With the Cardiovalve Transfemoral Mitral Valve System (AHEAD Study) Recruiting NCT03339115
169 The Effects of Degenerative Mitral Regurgitation on Cardiac Structure and Function, Symptoms, and Exercise Capacity Recruiting NCT04051411
170 Evaluation of the Safety and Performance of the Half Moon Transcatheter Mitral Valve Repair System in High Risk Patients With Severe, Symptomatic Mitral Regurgitation Recruiting NCT04343313
171 Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation (EXPLORE MR) Recruiting NCT04098328
172 Treatment of Concomitant Mitral Regurgitation by Mitral Valve Clipping in Patients With Successful Transcatheter Aortic Valve Implantation Recruiting NCT04009434
173 Percutaneous MitraClip Device or Surgical Mitral Valve REpair in PAtients With PrImaRy MItral Regurgitation Who Are Candidates for Surgery (REPAIR MR) Recruiting NCT04198870
174 Feasibility Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk Recruiting NCT04029363
175 3D Echocardiography and Cardiovascular PRognosis In Mitral REgurgitation (3D-PRIME) Recruiting NCT04442828
176 Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation (RESOLVE-MR) (Tendyne™ PMCF Study) Recruiting NCT04818502
177 Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using C-11 Acetate Cardiac PET-MRI Recruiting NCT04795856 Early Phase 1 [11C] acetate
178 Evaluation of the Efficacy and Safety of the Transcatheter Mitral Valve Repair System in Patients With Moderate and Above Degenerative Mitral Regurgitation at High Surgical Risk Recruiting NCT05021614
179 Dutch-AMR Study: Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Organic Mitral Regurgitation and Preserved Ejection Fraction: a Multicenter Registry Trial Recruiting NCT03975998
180 Prediction of Post-operative Left Ventricular Dysfunction in Primitive, Chronic Mitral Regurgitation Surgery With Preserved Ejection Fraction, by Pre-operative Global Longitudinal Strain Measure Recruiting NCT03968601
181 Cardiovalve Transfemoral Mitral Valve System in Patients at High Surgical Risk With Severe Mitral Regurgitation Recruiting NCT03958773
182 Improving Mitral Repair for Functional Mitral Regurgitation Recruiting NCT03366649
183 Determinants of the Progression and Outcome of Mitral Regurgitation-PROGRAM STUDY Recruiting NCT01835054
184 Assessment of the Carillon® Mitral Contour System® in Treating Heart Failure With at Least Mild Functional Mitral Regurgitation Recruiting NCT03142152
185 Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO Trial Recruiting NCT03242642
186 Randomized Comparison of Early Mitral ValvE Repair Versus Watchful Waiting for Asymptomatic SEvere Degenerative Mitral Regurgitation Due to Leaflet Prolapse Recruiting NCT03389542
187 Mitral Regurgitation Treatment in Advanced Heart Failure Recruiting NCT05292716
188 A RandomizEd Study of tHe MitrACliP DEvice in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation Recruiting NCT02444338
189 An Initial Evaluation of the Safety and Performance of the Transcatheter Mitral Valve Replacement System in Patients With Severe, Symptomatic Mitral Regurgitation Recruiting NCT02322840
190 Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry Recruiting NCT05332782
191 Beating Heart Mitral Valve REPair With the HARPOON™ System: ReaL World Outcomes From a multICenter observATional European Registry Recruiting NCT04393779
192 Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip: The V-Wave Shunt MitraClip Study Recruiting NCT04729933
193 European Multicentre Registry of Percutaneous Paravalvular Leak Closure - EuroPVL Study Recruiting NCT05506293
194 TENDyne European expeRience Registry Recruiting NCT04898335
195 Evaluation of The Minimally Invasive VenTouch™ System in The Treatment of Functional Mitral Valve Regurgitation (FMR): OUS Feasibility Study Recruiting NCT03616678
196 ENRAPT-MR Trial: Epicardial Mitral Repair Recruiting NCT03864848
197 SQ-Kyrin Transcatheter Mitral Valve Repair System Feasibility Study Recruiting NCT05040074
198 HighLife TSMVR Feasibility Study of the Open Cell CLARITY Valve in Patients With Moderate-severe or Severe MR, High Surgical Risk and With a High Risk for Left Ventricular Outflow Tract Obstruction (LVOTO) Recruiting NCT04888247
199 Choice of Optimal Transcatheter Treatment for Mitral Insufficiency Registry Recruiting NCT04688190
200 Mi-STITCH™ and Mi-KNOT™ Device Technologies Improvement of Minimally Invasive Mitral Valve Repair - A Single-center, Pilot Clinical Safety & Feasibility Trial Recruiting NCT05034471
201 Use of a Computerized Body Auscultation Device (©CompuSteth) for the Diagnosis of Structural Cardiac Pathologies Recruiting NCT04960280
202 Development of an Algorithm to Differentiate Heart Murmurs by Timing, Disease Type, and Severity in Adult Patients Using Electronic Stethoscopes Recruiting NCT04400513
203 Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Transcatheter Edge-to-edge Mitral Valve Repair Recruiting NCT04913727
204 Watchman for Patients With Atrial Fibrillation Undergoing Transcatheter Mitral Valve Repair (WATCH-TMVR) Recruiting NCT04494347
205 MitraClip® Registry - an Observational Study of Percutaneous Mitral Valve Repair Using the MitraClip® System Recruiting NCT02033811
206 Early Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System Recruiting NCT03813524
207 A Prospective, Multi-center Trial to Evaluate the Safety and Effectiveness of Beating Heart Mitral Valve Repair With the HARPOON™ System (RESTORE) Recruiting NCT04375332
208 Invasive Hemodynamic Response to Transcatheter Edge-to-Edge Mitral Valve Repair Recruiting NCT04200378
209 Cephea Early Feasibility Study Recruiting NCT05061004
210 Assessment of the Safety and Performance of the HARPOON™ Beating Heart Mitral Valve Repair System; a Multi-center Post-market Study (ASCEND) Recruiting NCT04382612
211 SAPIEN M3 System Transcatheter Mitral Valve Replacement Via Transseptal Access Recruiting NCT04153292
212 Impact of Mitral Valve Regurgitation on Coronary Haemodynamics and the Instantaneous Effect of Transcatheter Mitral Valve Repair: The MitraFLOW Study Recruiting NCT04245956
213 Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic Regurgitation Recruiting NCT04038879
214 AltaValve Early Feasibility Study Protocol Recruiting NCT03997305
215 Annuloplasty Rings and Band Post-Market Clinical Follow-Up (ARB-PMCF) Study Recruiting NCT04761120
216 Annuloplasty for the Treatment of Not-Severe Tricuspid Regurgitation in Patients Undergoing Surgery for Mitral Valve Disease: a Prospective, Spontaneous, Multicentre, Randomized Study Recruiting NCT02996552
217 The AcChord Study: A Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System Recruiting NCT04190602
218 Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock Recruiting NCT05298124
219 MITRA-EF: A Multi-Center Registry Evaluating Left Ventricular Function in Patients Undergoing Transcatheter Mitral Edge-To-Edge Repair Recruiting NCT05311163
220 The Role of Left Atrial Fibrosis in Mitral Valve Repair Surgery (ALIVE Trial) Recruiting NCT05345730
221 First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve System (MINERVA FIH) Recruiting NCT04775108
222 Personalized Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in Rehabilitation After Cardiac Operations (the PACO Trial) Recruiting NCT03470246
223 TransCranial Doppler for REDUCtion of Silent strokE During MitraClip Implantation Recruiting NCT04384198
224 Assessment of Digital Consultations on Clinical Impact and Efficiency Using a RCT (ADMINISTER) Trial Recruiting NCT05413447
225 Prognostic Impact of Non-invasive Imaging Parameters (Cardiac Echocardiography and MRI) in Patients With Primary Mitral Insufficiency (MI) by Prolapse: Observational Cohort, Monocentric (COHORTE-IM) Recruiting NCT03962023
226 Randomized Trial of the NeoChord™ DS1000™ System Versus Open Surgical Repair Recruiting NCT02803957
227 Belgian Mitraclip Registry Recruiting NCT02506387
228 Hemodynamic Estimation Per Procedure of the Result of the MitraClip Technique: Interest of the Ratio of Mean Arterial Pressure (MAP) to Pressure of the Mean Left Atrium (POG) Recruiting NCT05123430
229 The Society of Thoracic Surgeons/ American College of Cardiology Transcatheter Valve Therapies Registry Mitral Module Recruiting NCT02245763
230 Physiological Changes of the Mitral Annulus After Annuloplasty in Barlow Disease: an MRI-focused Study Recruiting NCT04418960
231 OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety and Effectiveness Evaluation (OPTIMISE II) Recruiting NCT03908983
232 EValuation of Outcomes of MitraCLip for the Treatment of Moderate Functional Mitral ValvE Regurgitation In Heart Failure Recruiting NCT03891823 Medical Therapy
233 Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥65 Year-olds (PRIMARY) Recruiting NCT05051033
234 Edwards EVOQUE Eos Mitral Valve Replacement: Investigation of Safety and Performance After Mitral Valve Replacement With Transcatheter Device (MISCEND) Recruiting NCT02718001
235 Evaluation of the Efficacy and Safety of the Mi-thos® Transcatheter Mitral Valve Replacement System in Patients With Severe Mitral Valve Disease at High Surgical Risk. Recruiting NCT04195984
236 The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry Recruiting NCT04577248
237 Impact of Preoperative Myocardial Fibrosis Related to Mitral Valve Prolapse on Postoperative Left Ventricular Remodeling Recruiting NCT05284058
238 Annular ReduCtion for Transcatheter Treatment of Insufficient Mitral ValvE (ACTIVE): A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Assess Transcatheter Mitral Valve Repair With Edwards Cardioband System and GDMT vs GDMT Alone in Patients With FMR and Heart Failure Active, not recruiting NCT03016975
239 A Clinical Evaluation of the Safety and Effectiveness of the MitraClip® System for the Treatment of Functional Mitral Regurgitation in Symptomatic Heart Failure Subjects (COAPT Recruitment Closed). COAPT CAS (Recruitment Closed) Active, not recruiting NCT01626079
240 An Initial Evaluation of the Carillon Mitral Contour System for Treatment of Atrial Function Mitral Regurgitation Active, not recruiting NCT04529928
241 Clinical Investigation of the Caisson Transcatheter Mitral Valve Replacement (TMVR) System for Percutaneous Mitral Valve Replacement in Patients With Symptomatic Mitral Regurgitation Active, not recruiting NCT03661398
242 HighLife™ Transcatheter Mitral Valve Replacement System for Severe Mitral Regurgitation in Patients at High Surgical Risk Active, not recruiting NCT02974881
243 ChordArt System Study for the Treatment of Mitral Regurgitation Due to Leaflet Prolapse or Flail Active, not recruiting NCT03581656
244 Transcatheter Edge to Edge Mitral Valve Repair Versus Standard Surgical Mitral Valve Operation for Secondadry Mitral Regurgitation Active, not recruiting NCT05090540
245 An Early Feasibility Study of the AccuCinch® Ventricular Restoration System in Patients With Prior Mitral Valve Intervention (PMVI) and Recurrent Mitral Regurgitation - The CorCinch-PMVI Study Active, not recruiting NCT03560167
246 Early Surgery Versus Conventional Treatment for Asymptomatic Patients With Severe Degenerative Mitral Regurgitation: A Propensity Analysis Active, not recruiting NCT01703806
247 Prognosis in Asymptomatic Mitral Regurgitation (PAMIR) Study Active, not recruiting NCT00509080
248 A Study to Evaluate the Feasibility and Safety of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation: (Millipede Feasibility Study) Active, not recruiting NCT04147884
249 Prospective Treatment Algorithm Guiding Repair of Severe Ischemic Mitral Regurgitation: Canadian Mitral Research Alliance (CAMRA) 2 Trial Active, not recruiting NCT03292497
250 Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation Active, not recruiting NCT03230747
251 Safety and Performance Evaluation of the AccuCinch® Ventricular Restoration System for the Treatment of Heart Failure With or Without Functional Mitral Regurgitation Due to Dilated Ischemic or Non-Ischemic Cardiomyopathy - The CorCinch-EU Study Active, not recruiting NCT03183895
252 Safety and Performance Study of the Harpoon Medical Transapical Suturing Device (TSD-5) in Subjects With Degenerative Mitral Regurgitation - CE Mark Study for the Harpoon Medical Device in Poland Active, not recruiting NCT02432196
253 Feasibility Study of the Tendyne Mitral Valve System for Use in Subjects With Mitral Annular Calcification Active, not recruiting NCT03539458
254 Prospective Analysis of the Feasibility of the PASCAL Spacer Technology for Transcatheter Mitral Valve Repair in an All-comers Cohort Active, not recruiting NCT04473092
255 Prospective Evaluation of Robotic-assisted Mitral Surgery With the daVinci X Surgical System: HUMANITAS Gavazzeni Contribution (Studio Dell'Applicazione Della Chirurgia Robotica Con Robot daVinci X (IS4200) di Ultima Generazione Sulla Valvulopatia Mitralica: Contributo di HUMANITAS Gavazzeni) Active, not recruiting NCT04415138
256 The Genebank at Scripps Clinic Registry Active, not recruiting NCT00722748
257 Early Feasibility Study of the CardioMech Mitral Valve Repair System (MVRS) Active, not recruiting NCT04820764
258 A Post-Market Study Assessment of the Safety and Performance of the MitraClip G4 System Active, not recruiting NCT04177394
259 Long-Term Follow-Up For Participants Of: Evaluation Of Outcomes Following Mitral Valve Repair/Replacement In SMR and Surgical Interventions For MMR Trials Active, not recruiting NCT03066050
260 Operative Mitralklappenrekonstruktion Bei Funktionellen Mitralklappenvitien Bei Reduzierter Systolischer Ventrikelfunktion Active, not recruiting NCT03470155
261 Edwards PASCAL Transcatheter Valve Repair System Registry: A Multicenter Observational Registry With the Edwards PASCAL Transcatheter Valve Repair System Active, not recruiting NCT04443218
262 MitraClip® and Hemodynamic Effects of Relevant Iatrogenic Atrial Septum Defect Closure - Evaluation of Morphologic and Functional Changes in a Randomized Setting Active, not recruiting NCT03024268
263 Early Feasibility Study of the AccuCinch® Ventricular Restoration System Active, not recruiting NCT02806570
264 Mitral TRans-Apical neoChordal Echo-guided Repair (TRACER) Trial Active, not recruiting NCT02768870
265 PARTNER 3 Trial - SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Mitral Bioprosthetic Valve Active, not recruiting NCT03193801
266 ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Aortic and Mitral Bioprostheses (Models 11000A and 11000M) With a New Tissue Treatment Platform (COMMENCE) Active, not recruiting NCT01757665
267 Carpentier-Edwards® Perimount Magna® Mitral Pericardial Bioprostheses Models 7000/7000 TFX and Carpentier-Edwards® Perimount Magna® Mitral Ease™ Pericardial Bioprostheses Models 7200TFX and 7300/7300TFX Active, not recruiting NCT00853632
268 Percutaneous Mitral Valve Replacement EvaLuation Utilizing IDE Early Feasibility Study (PRELUDE) Active, not recruiting NCT02768402
269 Tiara™ Transcatheter Mitral Valve Replacement Study (TIARA-II) Active, not recruiting NCT03039855
270 Mitral Valve Repair Clinical Trial (MAVERIC Trial) Active, not recruiting NCT02302872
271 Expanded Clinical Study of the Tendyne Mitral Valve System Active, not recruiting NCT02321514
272 Early Feasibility Study of the Neovasc Tiara™ Mitral Transcatheter Heart Valve With the Tiara™ Transapical Delivery System Active, not recruiting NCT02276547
273 The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study Active, not recruiting NCT03170349
274 A Prospective, Multicenter, Objective Performance Criteria Study to Evaluate the Safety and Effectiveness of Dragonfly Transcatheter Mitral Valve Repair System for the Treatment of Degenerative Mitral Regurgitation (DMR) Subjects. Enrolling by invitation NCT04734756
275 SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation Enrolling by invitation NCT04464876
276 The Effects of Biomechanical Taping on Individuals With Mechanical Low Back Pain With Increased Foot Pronation Enrolling by invitation NCT04776798
277 Clinical Correlation of a Novel Wearable Sensor to Detect Cardiovascular Mechanical and Electrical Properties Through Infrasonic Hemodynography Enrolling by invitation NCT04636892
278 Dragonfly-M Transcatheter Mitral Valve Repair System Early Feasibility Study Enrolling by invitation NCT04528576
279 ENRAPTUS Epicardial Mitral Touch System for Mitral Insufficiency Not yet recruiting NCT04396379
280 Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR Transfemoral System in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial Not yet recruiting NCT05496998
281 A Prospective, Multicenter, Single-group Target Value Clinical Study to Evaluate the Safety and Efficacy of JensClip Transcatheter Valve Repair System in the Treatment of Moderate to Severe Degenerative Mitral Regurgitation Not yet recruiting NCT05417945
282 Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation (EXPLORE DMR) Not yet recruiting NCT04679662
283 Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation (EXPLORE FMR) Not yet recruiting NCT04679714
284 European First in Human Study of the NeoChord Transcatheter Mitral Repair System to Assess Safety and Performance in Patients With Symptomatic Mitral Regurgitation Not yet recruiting NCT05425628
285 Assessment of Subclinical Left Atrial and Left Ventricular Dysfunction by Speckle Tracking Echocardiography in Severe Asymptomatic Rheumatic Mitral Regurgitation and Its Role in Predicting Outcome After Valve Replacement Compared to Guideline Parameters Not yet recruiting NCT03870516
286 Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Degenerative Mitral Regurgitation (EXPLORE DMR) Not yet recruiting NCT04666480
287 Effect of Significant Ischemic Mitral Regurgitation on the Outcome of ST Segment Elevation Myocardial Infarction Patients Treated With Primary Percutaneous Coronary Intervention Not yet recruiting NCT04106648
288 A Prospective, Multicenter, Objective Performance Criteria Clinical Study to Evaluate the Efficacy and Safety of the Transfemoral Mitral Valve Repair System in the Treatment of Patients With Moderately Severe and Severe Functional Mitral Regurgitation(FMR) Not yet recruiting NCT05508438
289 Comparative STudy chaRacterising the Physiological changEs Induced by Surgical and tranScatheter Mitral Regurgitation Reduction (STRESS-MR) Not yet recruiting NCT05403840
290 A Multicenter, Prospective, Single-arm Objective Performance Criteria Trial to Evaluate the Safety and Efficacy of the Transcatheter Mitral Valve Repair System: ValveClasp® in the Treatment of Moderate to Severe Mitral Regurgitation Not yet recruiting NCT05391802
291 Early Versus Deferred Aortic Valve Replacement in Patients With Moderate Aortic Stenosis Combined With Mitral Regurgitation: a Randomized Clinical Trial Not yet recruiting NCT05310461
292 Surgical Treatment of Aortic Valve Disease With Moderate Functional Mitral Regurgitation Not yet recruiting NCT05566340
293 Erector Spinae Plane Block for Minimally Invasive Mitral Surgery Not yet recruiting NCT04770961
294 Surgical Strategies in Moderate Ischemic Mitral Insufficiency in Patients Undergoing Coronary Artery Bypass Graft Not yet recruiting NCT04279678
295 An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System Not yet recruiting NCT04029337 Early Phase 1
296 A Prospective, Global Study Designed to Collect Real-world Clinical Outcomes of the MITRIS RESILIA Mitral Valve Not yet recruiting NCT05526560
297 TVMR With the Innovalve System Trial - Pilot Study in Italy Not yet recruiting NCT05010746
298 The GIOTTO4 Study: GISE Registry of Transcatheter Treatment of Mitral Valve Regurgitation With the MitraClip G4 Not yet recruiting NCT05455489
299 NHLBI Structural Heart and Valve Network Prospective Registry Not yet recruiting NCT03928639
300 TVMR With the Innovalve System Trial - Pilot Study in Belgium Not yet recruiting NCT05263375
301 NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study Suspended NCT03929913
302 Stress Echo for Ischemic Mitral Valve Surgery Suspended NCT04023058
303 Safety and Performance Study of the Harpoon Medical Device in Patients With Degenerative Mitral Regurgitation Terminated NCT03285724
304 POP Study: Plasty or Prosthesis to Treat Functional Mitral Regurgitation in Low Ejection Fraction Patients; a Randomized Prospective Controlled Study Terminated NCT00947921
305 Dutch AMR; Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Organic Mitral Regurgitation; a Multicenter, Randomised Trial. Terminated NCT01708265
306 A Feasibility Registry on Use of Actigraphy Monitoring in Degenerative Mitral Regurgitation (DMR) Subjects Receiving the MitraClip® Device Terminated NCT02858245
307 A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation Terminated NCT01772108
308 Evaluation of Safety and Performance of the Twelve Transcatheter Mitral Valve Replacement System in Patients With Severe, Symptomatic Mitral Regurgitation Terminated NCT02428010
309 HRT Observational Study of a Mitral Bridge in Patients With Moderate to Severe Mitral Valve Regurgitation to Evaluate Device Safety and Performance Terminated NCT03511716
310 REPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System Terminated NCT02703311
311 A Prospective Single Arm Clinical Trial Evaluating the MitraClip System in Australia and New Zealand Terminated NCT01301625
312 Evaluation of the Safety and Performance of the Medtentia Mitral Valve Repair System When Used in Adults Undergoing Mitral Valve Repair Surgery Terminated NCT01678144
313 MitrAl ValvE RepaIr Clinical Trial (MAVERIC Trial) - United States Terminated NCT03311295
314 CardioPAT Project - Reducing the Need for Allogenic Blood Transfusion After On-pump Cardiac Surgery With Intra- and Postoperative Use of a New Device: a Randomized Trial Terminated NCT02058134
315 A Clinical Study of the CardiAQ™ Transcatheter Mitral Valve Implantation (TMVI) System (Transapical Delivery System) Terminated NCT02478008
316 Feasibility Study of High Surgical Risk Patients With Severe Mitral Regurgitation Treated With the Cardiovalve Transfemoral Mitral Valve System Withdrawn NCT03714412
317 A European, Multicenter, Randomized Study Comparing the Effectiveness and Safety of Mitral Valve Repair With the NeoChord DS1000 Artificial Chordae Delivery System Versus Conventional Surgery in Patients With Severe Primary Mitral Regurgitation Due to Isolated Leaflet Prolapse Withdrawn NCT02829749
318 Noninferiority Trial of MitraClip Implantation Strategies: 1 Clip vs. 2 Clips in Patients With Functional Mitral Regurgitation (One-Plus-One) Withdrawn NCT03503851
319 The EXERCISE FMR Trial: An Initial Evaluation of the Carillon Mitral Contour System for Treatment of Exercise Induced Functional Mitral Regurgitation Withdrawn NCT05040451
320 Observational Study of Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation - Follow Up of the Former Participants in the RESHAPE-HF Trial (Abbott Vascular). Withdrawn NCT02444286
321 Acquisition of Objective Data During Transapical Neochordae Implantation Withdrawn NCT04709042
322 Evaluation of Outcomes of Cardiac Resynchronization Therapy and MitraClip for the Treatment of Low Ejection Fraction and Functional Mitral Valve Regurgitation in Heart Failure Withdrawn NCT02985268 Optimal Medical Therapy
323 Safety and Performance of the AccuCinch® Ventricular Repair System Withdrawn NCT02624960
324 Quality of Life Measures After Mitral Valve Repair in Non-Ischaemic Cardiomyopathy Withdrawn NCT00483236
325 Destiny Trial: Effects of Mitral Valve Annuloplasty With the Geoform Ring on Left Ventricular Geometry and Function in Patients With Cardiomyopathy Withdrawn NCT00428103
326 Early Feasibility Study of the CardiAQ™ Transcatheter Mitral Valve Implantation (TMVI) System (Transfemoral and Transapical Delivery Systems) Withdrawn NCT02515539

Search NIH Clinical Center for Mitral Valve Insufficiency

Cochrane evidence based reviews: mitral valve insufficiency

Genetic Tests for Mitral Valve Insufficiency

Genetic tests related to Mitral Valve Insufficiency:

# Genetic test Affiliating Genes
1 Mitral Regurgitation 28

Anatomical Context for Mitral Valve Insufficiency

Organs/tissues related to Mitral Valve Insufficiency:

MalaCards : Heart, Brain, Whole Blood, Lymph Node, Atrioventricular Node, Kidney, Lung

Publications for Mitral Valve Insufficiency

Articles related to Mitral Valve Insufficiency:

(showing 18384, show less)
# Title Authors PMID Year
A Screening Approach to Identify Clinically Actionable Variants Causing Congenital Heart Disease in Exome Data. 5
29555671 2018
Relationship between the tissue Doppler-derived Tei index and plasma brain natriuretic peptide levels in patients with mitral regurgitation. 53 62
20329488 2010
Comparison of clinical presentations and outcomes between patients with TGFBR2 and FBN1 mutations in Marfan syndrome and related disorders. 53 62
19996017 2009
Tei index correlates with tissue Doppler parameters and reflects neurohormonal activation in patients with an abnormal transmitral flow pattern. 53 62
19558518 2009
BNP in mitral valve restrictive annuloplasty for ischemic mitral regurgitation. 53 62
18657328 2009
Prospective validation of the prognostic usefulness of brain natriuretic peptide in asymptomatic patients with chronic severe mitral regurgitation. 53 62
19744620 2009
Decline of plasma brain natriuretic peptide during enzyme replacement therapy in a female patient with heterozygous Fabry's disease. 53 62
19282651 2009
Successful catheter ablation to accessory atrioventricular pathway as cardiac resynchronization therapy in a patient with dilated cardiomyopathy. 53 62
19028709 2009
Predictors of mortality from pump failure and sudden cardiac death in patients with systolic heart failure and left ventricular dyssynchrony: results of the CARE-HF trial. 53 62
18926439 2008
Dynamic left ventricular dyssynchrony contributes to B-type natriuretic peptide release during exercise in patients with systolic heart failure. 53 62
18319268 2008
Correlation of the myocardial performance index with plasma B-type natriuretic peptide levels in patients with mitral regurgitation. 53 62
17541723 2008
Elevated B-type natriuretic peptide despite normal left ventricular function on rest and exercise stress echocardiography in mitral regurgitation. 53 62
18202251 2008
The combination of B-type natriuretic peptide and C-reactive protein provides incremental prognostic value among older patients referred for cardiac catheterization. 53 62
17617749 2007
Assessment of factors affecting plasma BNP levels in patients with chronic atrial fibrillation and preserved left ventricular systolic function. 53 62
16959341 2007
Usefulness of the brain natriuretic peptide to atrial natriuretic peptide ratio in determining the severity of mitral regurgitation. 53 62
17380223 2007
Significance of brain natriuretic peptide in the evaluation of symptoms and the degree of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy. 53 62
17243506 2006
Association of B-type natriuretic peptide activation to left ventricular end-systolic remodeling in organic and functional mitral regurgitation. 53 62
16563910 2006
Predictors of remodeling in the CRT era: influence of mitral regurgitation, BNP, and gender. 53 62
16624682 2006
Efficacy of nasal bi-level positive airway pressure in congestive heart failure patients with cheyne-stokes respiration and central sleep apnea. 53 62
16041159 2005
Plasma BNP levels are determined by the severity of left ventricular systolic dysfunction but not the types of underlying heart disease. 53 62
15999470 2005
B-type natriuretic peptide in organic mitral regurgitation: determinants and impact on outcome. 53 62
15883225 2005
Clinical applications of B-type natriuretic peptide levels in the care of cardiovascular patients. 53 62
15729209 2004
Changes in type B natriuretic peptide (BNP) concentrations during cardiac valve replacement. 53 62
15144992 2004
Plasma B-type natriuretic peptide levels in systolic heart failure: importance of left ventricular diastolic function and right ventricular systolic function. 53 62
15013124 2004
[Autoantibodies: new upstream targets of paroxysmal atrial fibrillation in patients with congestive heart failure]. 53 62
12463096 2002
Atrial natriuretic factor and mitral valve prolapse syndrome. 53 62
11533551 2001
Clinical correlates of elevated plasma natriuretic peptides and Big endothelin-1 in a population of ambulatory patients with heart failure. A substudy of the Italian Network on Congestive Heart Failure (IN-CHF) registry. IN-CHF Investigators. 53 62
10824729 2000
Acute mitral regurgitation due to chordal rupture in a patient with neonatal Marfan syndrome caused by a deletion in exon 29 of the FBN1 gene. 53 62
10441700 1999
Plasma atrial and brain natriuretic peptide levels in dogs with congestive heart failure. 53 62
10379945 1999
Hemodynamic correlates of atrial natriuretic peptide concentration in unselected patients with heart disease of different etiologies. 53 62
9887389 1998
Effect of continuous positive airway pressure on mitral regurgitant fraction and atrial natriuretic peptide in patients with heart failure. 53 62
9283534 1997
Associations between atrial natriuretic peptides, echocardiographic findings and mortality in an elderly population sample. 53 62
9159597 1997
Plasma atrial natriuretic peptide is elevated in patients with hypertrophic cardiomyopathy. 53 62
8842784 1996
Ventricular adenine nucleotide translocator mRNA is upregulated in dilated cardiomyopathy. 53 62
8252591 1993
A new and rare form of Williams' syndrome. 53 62
8351994 1993
[Correlations between plasma concentrations of atrial natriuretic factor and right ventricular function in patients with severe cardiac failure]. 53 62
1532302 1992
Dynamics of creatine kinase shuttle enzymes in the human heart. 53 62
1909638 1991
[Supravalvular aortic stenosis syndrome with advanced mitral regurgitation requiring extended aortoplasty and mitral valve replacement: a case report]. 53 62
2038171 1991
[Changes in PTCA. A model of ischemia in humans]. 53 62
1830715 1991
Estimation of Simulated Left Ventricle Elastance Using Lumped Parameter Modelling and Gradient-Based Optimization With Forward-Mode Automatic Differentiation Based on Synthetically Generated Noninvasive Data. 62
36082474 2023
Amlodipine decreases mitral regurgitation volume in dogs over 7 days: A study of 24 dogs with myxomatous mitral valve degeneration. 62
35414938 2022
Usefulness of computed tomography to predict residual mitral regurgitation after transcatheter mitral valve edge-to-edge repair. 62
35963710 2022
An autopsy case of sudden unexpected death with Barlow's disease. 62
35952984 2022
Mitral valve repair and tricuspid annuloplasty for Coffin-Lowry syndrome. 62
36069024 2022
Real-world clinical outcomes of percutaneous transluminal septal myocardial ablation for patients with drug-refractory hypertrophic obstructive cardiomyopathy: results from a retrospective multicenter registry of non-high-volume centers. 62
35641828 2022
Incidence and Predictors of New-Onset Atrial Fibrillation After Transcatheter Edge-to-Edge Repair of the Mitral Valve (from the Nationwide Readmissions Database). 62
36075754 2022
Artificial chordae for mitral valve repair. 62
36116053 2022
Mitral Annulus Geometry and Dynamic Motion Changes in Patients With Aortic Regurgitation: A Three-Dimensional Transesophageal Echocardiographic Study. 62
35811278 2022
Letter to the editor: "Papillary muscle intervention versus mitral ring annuloplasty in ischemic mitral regurgitation". 62
35916153 2022
Mitral Regurgitation and Mortality Risk in Medicare Beneficiaries With Heart Failure and Preserved Ejection Fraction. 62
36100504 2022
Outcomes in Patients With High Transmitral Gradient After Mitral Valve Transcatheter Edge-to-Edge Repair for Mitral Regurgitation. 62
36075753 2022
Percutaneous Repair of Mitral Regurgitation: A Comprehensive Review of Literature. 62
35872053 2022
Mitral Regurgitation in the High-Risk Patient: Integrating an Expanding Armamentarium of Transcatheter Devices Into the Treatment Algorithm. 62
34380944 2022
Functional Mitral Regurgitation After Aortic Valve Replacement in Aortic Incompetence: Another piece to the puzzle. 62
35965229 2022
Impact of Left Ventricular Global Longitudinal Strain on Outcomes After Transcatheter Edge-to-Edge Repair in Secondary Mitral Regurgitation. 62
36075752 2022
Severe mitral regurgitation in a patient with left-ventricular endomyocardial fibrosis: a challenging case. 62
36245853 2022
Association Between Sacubitril/Valsartan Initiation and Mitral Regurgitation Severity in Heart Failure With Reduced Ejection Fraction: The PROVE-HF Study. 62
36183276 2022
Transcatheter Mitral Valve Interventions for Mitral Regurgitation: A Review of Mitral Annuloplasty, Valve Replacement, and Chordal Repair Devices. 62
35871885 2022
Analysis of changes in "mitral valve reserve" after coronary artery bypass grafts in patients with functional mitral regurgitation. 62
36199145 2022
Mortality prediction of the frailty syndrome in patients with severe mitral regurgitation. 62
36251050 2022
Late Durability of Mitral Repair for Ischemic Versus Nonischemic Functional Mitral Regurgitation. 62
34547301 2022
Prognostic impact of left ventricular global longitudinal strain in atrial mitral regurgitation. 62
36270784 2022
Prognostic implications of mitral valve geometry in patients with secondary mitral regurgitation: the COAPT trial. 62
36265184 2022
Heartbeat: medical therapy, not just mechanical intervention, for optimal outcomes in patients with secondary mitral regurgitation. 62
36229055 2022
Spatio-temporal complexity of vena contracta and mitral regurgitation grading using 3D echocardiographic analysis. 62
36208654 2022
Isolated OPCABG in moderate chronic ischemic mitral regurgitation: is it a justifiable alternative approach ? 62
35524035 2022
Update on surgical repair in functional mitral regurgitation. 62
34165825 2022
Mitral Valve Surgery for Persistent or Recurrent Mitral Regurgitation After Transcatheter Edge-to-Edge Repair Is Associated With Improved Survival. 62
36250668 2022
Metabolomics implicate eicosanoids in severe functional mitral regurgitation. 62
36217578 2022
Properly Downsized Annuloplasty for Functional Mitral Regurgitation: Unbeaten in the Right Patient. 62
34780761 2022
Differences in patterns of progression of secondary mitral regurgitation. 62
36256596 2022
Prognosis for Mitral Valve Repair Surgery in Functional Mitral Regurgitation. 62
35851568 2022
Treatment of Severe Left Ventricular Outflow Tract Obstruction and Mitral Regurgitation With Alcohol Septal Ablation. 62
36247378 2022
Multimodality imaging for the management of patients with primary mitral regurgitation. 62
36218209 2022
Chordal replacement and annuloplasty in one transfemoral device for degenerative mitral regurgitation. 62
35587183 2022
Latent class analysis to predict outcomes after surgery for primary mitral regurgitation: a scientific validation of common sense. 62
36270783 2022
Predicting Stroke and Mortality in Mitral Regurgitation: A Machine Learning Approach. 62
36261105 2022
Combined Surgical Correction of Mitral Regurgitation. 62
34695408 2022
Prognostic values of exercise echocardiography and cardiopulmonary exercise testing in patients with primary mitral regurgitation. 62
34751769 2022
Recurrent or Persistent Mitral Regurgitation After Transcatheter Edge-to-Edge Repair: It Is a Big Deal! 62
36250660 2022
Acute iatrogenic complications after mitral valve repair. 62
36273407 2022
Mitral Annular Elasticity Determines Severity of Regurgitation in Barlow's Mitral Valve Disease. 62
35842077 2022
The Evolution of Transcatheter Therapies for Mitral Valve Disease: From Mitral Valvuloplasty to Transcatheter Mitral Valve Replacement. 62
33383168 2022
Surgical repair of a posterior left ventricular aneurysm in a 4-year-old boy. 62
35821584 2022
Observed versus expected morbidity and mortality in patients undergoing mitral valve repair. 62
36205629 2022
Prediction of Death or HF Hospitalization in Patients With Severe FMR: The COAPT Risk Score. 62
36202557 2022
MitraClip procedure assisted with 3-dimensional electro anatomical mapping system. 62
36187317 2022
Hemodynamic and Echocardiographic Predictors of Mortality in Pediatric Patients on Venoarterial Extracorporeal Membrane Oxygenation - A Multicenter Investigation. 62
36228840 2022
Differences in Cardiac Remodeling in Left-Sided Valvular Regurgitation: Implications for Optimal Definition of Significant Aortic Regurgitation. 62
35842362 2022
Numerical modeling for efficiency and endurance assessment of an indirect mitral annuloplasty device. 62
36215769 2022
Transcatheter mitral valve-in-valve replacement transeptally using a novel balloon-expandable device. 62
35949139 2022
Effectiveness and cost-efficacy of diuretics home administration via peripherally inserted central venous catheter in patients with end-stage heart failure. 62
35853499 2022
Augmenting mitral valve repair evaluation with intraoperative left ventricle pressure measurements. 62
36173329 2022
Guideline-directed medical therapy after transcatheter edge-to-edge mitral valve repair. 62
35672114 2022
Respect or resect in Barlow disease. 62
36183379 2022
Robotic mitral valve plasty for isolated clefts of mitral valve leaflets. 62
35488502 2022
Immediate maternal and fetal outcome following percutaneous mitral valve balloon commissurotomy: a 6-year single-center experience from sub-Saharan Africa. 62
35129101 2022
Artificial papillary muscle device for off-pump transapical mitral valve repair. 62
33451843 2022
Robotic vs. minimally invasive mitral valve repair: A 5-year comparison of surgical outcomes. 62
35989503 2022
Primeval outcomes of thoracoscopic transmitral myectomy with anterior mitral leaflet extension for hypertrophic obstructive cardiomyopathy. 62
35842814 2022
Transcatheter mitral valve-in-valve: treatment of rheumatic heart disease in young patients. 62
36200709 2022
Mitral valve repair in severe mitral regurgitation after blunt chest trauma. 62
36035601 2022
Successful management of a patient with preoperative respiratory failure due to a solid giant retroperitoneal tumor: a case report. 62
36244982 2022
Measures to improve in-hospital outcomes of patients undergoing surgical repair for anomalous origin of left coronary artery from pulmonary artery. 62
36254913 2022
A New Insight Into Nonbacterial Thrombotic Endocarditis: A Systematic Review of Cases. 62
36052565 2022
Role of matrix metalloproteinases in mitral valve regurgitation: Association between the of MMP-1, MMP-9, TIMP-1, and TIMP-2 expression, degree of mitral valve insufficiency, and pathologic etiology. 62
35801499 2022
Midterm Outcomes of Isolated Coronary Artery Bypass Grafting in the Setting of Moderate Ischemic Mitral Regurgitation. 62
35689983 2022
Surgical Results of Mitral Valve Repair for Mitral Regurgitation in Pediatric Patients with Mitral Valve Prolapse. 62
35362780 2022
The Role of Stress Echocardiography in Valvular Heart Disease. 62
36040552 2022
Homelessness and race are mortality predictors in US Veterans undergoing CABG. 62
36223817 2022
Artificial intelligence-enabled phenotyping of patients with severe aortic stenosis: on the recovery of extra-aortic valve cardiac damage after transcatheter aortic valve replacement. 62
36261218 2022
Aortic stenosis and mitral regurgitation modify the effect of venoarterial extracorporeal membrane oxygenation on left ventricular function in cardiogenic shock. 62
36224296 2022
Incessant non-sustained ventricular tachycardia immediately after MitraClip placement: a case report. 62
36225805 2022
Impact of left atrial appendage fibrosis on atrial fibrillation in patients following coronary bypass surgery. 62
35864729 2022
Value of the systemic immune-inflammation index in predicting poor postoperative outcomes and the short-term prognosis of heart valve diseases: a retrospective cohort study. 62
36220322 2022
Analysis between high risk of myocardial infarction with non-obstructive coronary artery disease in single center and occurrence of major adverse cardiovascular events. 62
36217554 2022
Rescue ross procedure and mitral valve repair on a low birth weight preterm neonate. 62
35989513 2022
Surgical explantation of quaternate transcatheter aortic valve replacement bioprostheses: a case report. 62
36253860 2022
[Mitral Valve Regurgitation Exacerbated by Aortic Dissection:Report of a Case]. 62
36176255 2022
Mitral regurgitation in hypertrophic obstructive cardiomyopathy: The role of the edge-to-edge technique. 62
36054469 2022
Association of Preoperative Sleep-Disordered Breathing With Functional Status After Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy. 62
36254322 2022
Natural language processing for identification of hypertrophic cardiomyopathy patients from cardiac magnetic resonance reports. 62
36258218 2022
Ventricular Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy (Analysis Spanning 60 Years Of Practice): AJC Expert Panel. 62
35965115 2022
Transapical Ventricular Remodeling for Hypertrophic Cardiomyopathy With Systolic Cavity Obliteration. 62
35339438 2022
Double root translocation: Early experience on performance of translocated aortic and pulmonary root. 62
35971235 2022
Effect of mitral valve transcatheter edge-to-edge repair on indices of left atrial performance in chronic mitral regurgitation. 62
36258636 2022
Aetiology of chronic heart failure in patients from a super-aged society: the KUNIUMI registry chronic cohort. 62
36151724 2022
Prognostic value of left atrial strain quantification from 2D ultrasound imaging in post-ischemic heart failure patients: evidence from the REMODEL-HF study. 62
35504452 2022
Survival benefit of overweight patients undergoing MitraClip® procedure in comparison to normal-weight patients. 62
36070481 2022
Aortic root aneurysm in a patient with Aarskog-Scott syndrome. 62
35703394 2022
Is there referral bias in outcomes of septal myectomy for hypertrophic cardiomyopathy? 62
33190872 2022
Surgical Management of Hypertrophic Cardiomyopathy Complicated by Infective Endocarditis. 62
35120877 2022
Left ventricular remodeling following septal myectomy in hypertrophic obstructive cardiomyopathy. 62
36172435 2022
Effect of Mitral Regurgitation on Left Ventricular Deformation in Myocardial Infarction Patients: Evaluation by Cardiac Magnetic Resonance Imaging. 62
35130580 2022
Two hundred robotic mitral valve repair procedures for degenerative mitral regurgitation: the Yale experience. 62
36237593 2022
Ventricular Septal Myectomy Decreases Long-Term Risk for Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy. 62
35835601 2022
Role of computed tomography in transcatheter replacement of 'other valves': a comprehensive review of preprocedural imaging. 62
35994705 2022
Unveiling Cardiac Amyloidosis, its Characteristics, and Outcomes Among Patients With MR Undergoing Transcatheter Edge-to-Edge MV Repair. 62
36008266 2022
Surgical correction of total anomalous pulmonary venous return in an adult patient. 62
36123587 2022
Cryoablation of Papillary Muscles at Surgery for Malignant Ventricular Arrhythmias Due to Mitral Valve Prolapse. 62
35697646 2022
Anomalous Aortic Origin of the Right Coronary Artery Incidentally Detected In a Patient with Degenerative Mitral Valve Disease. 62
36123028 2022
Myocardial Fibrosis at Cardiac MRI Helps Predict Adverse Clinical Outcome in Patients with Mitral Valve Prolapse. 62
36098639 2022
Impact of Pulmonary Hypertension on Mortality after Surgery for Aortic Stenosis. 62
36143909 2022
Mitral Valve Endocarditis Secondary to Nasal Irrigation Use in Chronic Allergic Rhinitis. 62
36225488 2022
Machine learning based model for risk prediction after ST-Elevation myocardial infarction: Insights from the North India ST elevation myocardial infarction (NORIN-STEMI) registry. 62
35577162 2022
Sentinel Lymph Node Mapping and Staging Surgery Via Gasless Transvaginal Natural Orifice Transluminal Endoscopic Surgery: A Case Report of an Endometrial Cancer Patient and Comorbid Rheumatic Heart Disease. 62
36071639 2022
Right heart failure in the setting of thyrotoxic valvulopathy: the pathophysiology of an often neglected diagnosis: a case report. 62
36072425 2022
Reversible acute severe mitral regurgitation accompanying ventricular tachycardia and ventricular fibrillation. 62
33609221 2022
Outcomes and risk analysis after tricuspid valve surgery for non-Ebstein 2-ventricle congenital tricuspid valve diseases. 62
36172453 2022
Valvular disease burden in the modern era of percutaneous and surgical interventions: the UK Biobank. 62
36104095 2022
Mitral valve surgery for atrial functional mitral regurgitation: predicting recurrent mitral regurgitation and mid-term outcome. 62
35239104 2022
Undersizing mitral annuloplasty alters left ventricular mechanics in a swine model of ischemic mitral regurgitation. 62
33288234 2022
A multiparameter algorithm to guide repair of degenerative mitral regurgitation. 62
33168163 2022
Occlusion of the os of the left coronary artery by dysplastic aortic valve tissue presenting as progressive mitral insufficiency and cardiac arrest. 62
36102120 2022
Acute Mitral Valve Regurgitation Presenting With Right Upper Lobe Opacification. 62
36259023 2022
Treatment of severe acute mitral regurgitation following thoracoabdominal aortic aneurysm repair. 62
35726670 2022
ECPELLA as the bridge to surgery in patients with cardiogenic shock due to post-infarct papillary muscle rupture: management of mechanical circulatory support during operation. 62
36112331 2022
Acute aortic regurgitation due to fibrous strand rupture. 62
35690898 2022
Conduction system pacing vs. biventricular pacing in patients with ventricular dysfunction and AV block. 62
35583311 2022
Prevalence of Echocardiographic Evidence of Trace Mitral and Aortic Valve Regurgitation in 50 Clinically Healthy, Young Adult Labrador Retrievers without Heart Murmur. 62
36139302 2022
Diffuse Decreased Blood Flow in the Right Lung: Mitral Regurgitation-induced Pulmonary Hypertension. 62
35736217 2022
Caudal pulmonary artery to vein ratio on radiography can predict pulmonary hypertension in dogs with mitral regurgitation. 62
36049080 2022
Substitute parameters of exercise-induced pulmonary hypertension and usefulness of low workload exercise stress echocardiography in mitral regurgitation. 62
36155621 2022
[Chinese expert consensus on transcatheter edge-to-edge repair for patients with severe mitral valve regurgitation]. 62
36096702 2022
Early Rehabilitation for Cerebellar Complications Following Left Atrial Myxoma Excision: A Stitch in Time Saves Nine. 62
36225469 2022
Case series of transcatherter edge-to-edge repair using MitraClip™ system with Impella® mechanical circulatory support. 62
36147932 2022
Midterm outcomes of mitral valve repair versus replacement in elderly patients: A propensity score-matched analysis. 62
36168792 2022
Factors associated with an unsuccessful fast-track course following minimally invasive surgical mitral valve repair. 62
36069638 2022
Mortality and morbidity of surgical and transcatheter mitral valve repair in octogenarians: A systematic review. 62
35652892 2022
Risk Factors for Left Ventricular Thrombus Formation in Patients with Dilated Cardiomyopathy. 62
36108652 2022
Finite element analysis of mitral valve annuloplasty in Barlow's disease. 62
35963102 2022
Effect of Next Generation Pulsatile Mechanical Circulatory Support on Cardiac Mechanics: The PULSE Trial. 62
35331637 2022
Imaging in transcatheter native mitral valve replacement with Tendyne mitral valve system: Echocardiographic pathway for the interventional imager. 62
36069642 2022
MitraClip implantation plus left atrial appendage occlusion in a hereditary hemorrhagic telangiectasia patient. 62
36128856 2022
Kat-ARC accelerated 4D flow CMR: clinical validation for transvalvular flow and peak velocity assessment. 62
36131185 2022
Mitral Valve Replacement: A Review of Current Practices and Considerations in Low and High-Risk Patients. 62
36155202 2022
Hemodynamic Profiles and Clinical Response to Transcatheter Mitral Repair. 62
36075641 2022
Outcome of submitral aneurysm. 62
35671348 2022
Acute Ischaemic Mitral Valve Regurgitation. 62
36233410 2022
Fluid structure computational model of simulating mitral valve motion in a contracting left ventricle. 62
35816854 2022
Clinical Outcomes With Transcatheter Edge-to-Edge Repair in Atrial Functional MR From the EXPAND Study. 62
36075643 2022
Dynamic changes in the three-dimensional mitral complex geometry in a case of takotsubo cardiomyopathy with transient systolic anterior movement of the mitral valve. 62
36091618 2022
Remote Dielectric Sensing to Assess Residual Pulmonary Congestion Following Percutaneous Mitral Valve Repair. 62
36143970 2022
Transcatheter edge-to-edge repair following surgical valve repair with ring implantation: Results from the multicentre "Clip-in-Ring" registry. 62
36115768 2022
Clinical outcomes and predictors in patients with previous cardiac surgery undergoing mitral valve transcatheter edge-to-edge repair. 62
35644994 2022
Outcomes of loop technique with ring annuloplasty: a > 10-year experience. 62
35349037 2022
Impact of procedural success on clinical outcome after MitraClip: Results from the MITRA-FR trial. 62
36244966 2022
Contemporary Management of Ischemic Mitral Regurgitation at Coronary Artery Bypass Grafting. 62
36150477 2022
Urgent Transcatheter Edge-to-Edge Repair for Severe Mitral Regurgitation in Patients with Refractory Cardiogenic Shock. 62
36233485 2022
Significance of Left Ventricular Ejection Time in Primary Mitral Regurgitation. 62
35778308 2022
Transcatheter Edge-to-Edge Repair for Atrial Secondary Mitral Regurgitation. 62
36075644 2022
Functional Mitral Regurgitation Staging and its Relationship to Outcomes in the COAPT Trial. 62
36075650 2022
Results of different therapeutic strategies for left ventricular aneurysm with mitral regurgitation. 62
35383590 2022
The impact of transcatheter edge-to-edge repair on right ventricle-pulmonary artery coupling in patients with functional mitral regurgitation. 62
36075584 2022
Sex-specific impact of anthropometric parameters on outcomes after transcatheter edge-to-edge repair for secondary mitral regurgitation. 62
36115443 2022
Long-term Outcomes of Papillary Muscle Relocation Anteriorly for Functional Mitral Regurgitation. 62
36130272 2022
Geometric differences of the mitral valve apparatus in atrial and ventricular functional mitral regurgitation. 62
35361564 2022
A Novel Approach for Semiautomated Three-Dimensional Quantification of Mitral Regurgitant Volume Reflects a More Physiologic Approach to Mitral Regurgitation. 62
35605896 2022
Color Doppler Splay in Mitral Regurgitation: Hemodynamic Correlates and Outcomes in a Clinical Cohort. 62
35472569 2022
Transcatheter edge to edge repair using the ease-of-use valve clamp system for functional mitral regurgitation: a primary report. 62
36088621 2022
Left atrial myocardial intrinsic function remodeling response to repair of primary mitral regurgitation. 62
36074005 2022
Outcomes After Transcatheter Edge-to-Edge Mitral Valve Repair According to Mitral Regurgitation Etiology and Cardiac Remodeling. 62
36075642 2022
Randomized Comparison of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation in Prohibitive Surgical Risk Patients. 62
36121247 2022
Medical Therapy for Functional Mitral Regurgitation. 62
35862021 2022
Transcatheter Edge-to-Edge Repair in Patients with Severe Mitral Regurgitation and Cardiogenic Shock: TVT Registry Analysis. 62
36126766 2022
Closing the door in front of a torrential mitral regurgitation. 62
36126333 2022
Mineralocorticoid Receptor Antagonists Mitigate Mitral Regurgitation-Induced Myocardial Dysfunction. 62
36078158 2022
Cost-effectiveness of the MitraClip device in secondary mitral regurgitation: comment upon the article by Estler et al. 62
36057885 2022
Relation of Myocardial Work Indexes and Forward Flow Reserve in Patients With Significant Secondary Mitral Regurgitation Undergoing Transcatheter Mitral Valve Repair. 62
35835599 2022
Fate of moderate secondary mitral regurgitation in patients undergoing aortic valve replacement for severe aortic regurgitation. 62
35671345 2022
Commentary: The over and under on ischemic mitral regurgitation repair. 62
33189338 2022
A case of hypoplastic posterior mitral leaflet-related severe mitral regurgitation associated with ostium secundum atrial septal defect. 62
35861601 2022
Commentary: Ischemic mitral regurgitation: From annular restriction to papillary approximation, is it time to reconsider the lost technique? 62
33218759 2022
Commentary: Repair of degenerative mitral regurgitation: Science, art, or both? 62
33220968 2022
Three-dimensional echocardiography for predicting mitral stenosis after MitraClip for functional mitral regurgitation. 62
35084686 2022
Ambulatory Pulmonary Artery Pressures After Transcatheter Edge-to-Edge Repair of the Mitral Valve in Patients With Heart Failure and Mitral Regurgitation. 62
36163050 2022
Percutaneous Mitral Valve Repair in Cardiac Amyloidosis and Severe Mitral Regurgitation. 62
34078542 2022
Quantification of mitral regurgitation after transcatheter edge-to-edge repair: Comparison of echocardiography and patient-specific in silico models. 62
35872413 2022
Incidence and Causal Association of Functional Atrial Mitral Regurgitation in HFpEF. 62
36181999 2022
Machine Learning for Pediatric Echocardiographic Mitral Regurgitation Detection. 62
36191670 2022
Transcatheter Edge-to-Edge Repair for Atrial Functional Mitral Regurgitation: Effective Therapy or Elusive Target? 62
36075645 2022
Three-Dimensional Echocardiographic Evaluation of Indentations of the Posterior Mitral Leaflet and Their Impact on Secondary Mitral Regurgitation. 62
35961605 2022
Optimal heart rate modulation therapy using ivabradine for those with decompensated heart failure and mitral regurgitation. 62
35949570 2022
Significance of Spontaneous Echocardiographic Contrast in Transcatheter Edge-to-Edge Repair for Mitral Regurgitation. 62
36049594 2022
Reappraisal of the Regurgitation Severity vs Left Ventricular Dilation Conceptual Framework for the Management of Secondary Mitral Regurgitation. 62
35964888 2022
Ischemic Mitral Regurgitation and Leaflet Remodeling: Another Arrow Hits the Target. 62
35902174 2022
Transcatheter edge-to-edge repair in patients with mitral regurgitation and cardiogenic shock: a new therapeutic target. 62
35856980 2022
Acute effect of edge-to-edge repair of mitral regurgitation on left heart mechanics and health status. 62
36166336 2022
Mitral regurgitation management: a systematic review of clinical practice guidelines and recommendations. 62
34878118 2022
Impact of asymmetric tethering on outcomes after edge-to-edge mitral valve repair for secondary mitral regurgitation. 62
34786592 2022
Functional Mitral Regurgitation in Heart Failure: Analysis of the ESC Multidisciplinary Heart-Team Position Statement and Review of Current Guidelines. 62
34607763 2022
Myocardial Stunning With Severe Functional Mitral Regurgitation in Transcatheter Aortic Valve Replacement - Temporal Change in Transesophageal Echocardiographic Findings. 62
36032382 2022
Delayed hospitalisation for heart failure after transcatheter repair or medical treatment for secondary mitral regurgitation: a landmark analysis of the MITRA-FR trial. 62
35611516 2022
Usefulness of P-wave peak time as an electrocardiographic parameter in predicting left ventricular diastolic dysfunction in patients with mitral regurgitation. 62
35972827 2022
Extracardiac basal annuloplasty for the treatment of secondary mitral regurgitation. 62
35950967 2022
Clinical Impact of Tricuspid Regurgitation on Transcatheter Edge-to-Edge Mitral Valve Repair for Mitral Regurgitation. 62
35398010 2022
The Role of Cardiac Resynchronization Therapy for the Management of Functional Mitral Regurgitation. 62
35954250 2022
Transcatheter Mitral Valve Repair in Disproportionate Secondary Mitral Regurgitation. 62
35292389 2022
Acquired double-orifice mitral valve with severe mitral regurgitation. 62
35965605 2022
Quantitating Mitral Regurgitation in Clinical Trials: The Need for a Uniform Approach. 62
33838121 2022
Letter to the Editor: Rationale for Using Multiple Echo-Doppler Methods to Quantify Mitral Regurgitation. 62
35934264 2022
Functional anatomy and echocardiographic assessment in secondary mitral regurgitation. 62
35998280 2022
Paroxysmal massive mitral regurgitation. 62
35714167 2022
Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure. 62
35294624 2022
Fully Automated 3D Segmentation and Diffeomorphic Medial Modeling of the Left Ventricle Mitral Valve Complex in Ischemic Mitral Regurgitation. 62
35772323 2022
Mitral valve surgery after failed transcatheter edge-to-edge repair. 62
35967213 2022
[Mitral valve: When conservative, when surgical, when interventional therapy?] 62
35970185 2022
Coaptation length predicts early- and intermediate-term durability following degenerative mitral repair. 62
36125068 2022
Safe launch of a robotically assisted mitral valve repair program in a single center: experience of initial 20 cases under the Center for Minimally Invasive Surgery. 62
35969291 2022
Edge-to-Edge Technique Used as a Bailout for Suboptimal Mitral Repair: Long-term Results. 62
35987343 2022
Accessory left atrial cords: A case report and literature review. 62
35578332 2022
Idiopathic Extremity Arteriovenous Fistula: A Rare Etiology of Cardiac Failure. 62
36176886 2022
Effects of Cyproheptadine on Mitral Valve Remodeling and Regurgitation After Myocardial Infarction. 62
35902173 2022
Mitral Valve Repair for Anterior/Bi-leaflet Versus Posterior Leaflet Degenerative Mitral Valve Disease: A Systematic Review and Meta-analysis. 62
35970298 2022
Transcatheter mitral valve repair for inotrope dependent cardiogenic shock - Design and rationale of the CAPITAL MINOS trial. 62
36002047 2022
Anomalous inferior vena cava drainage in a patient undergoing cardiac surgery. 62
35575405 2022
Right ventricular dysfunction predicts outcome after transcatheter mitral valve repair for primary mitral valve regurgitation. 62
36054557 2022
Effects of Atrial Ischemia on Left Atrial Remodeling in Patients with ST-Segment Elevation Myocardial Infarction. 62
35977632 2022
Hybrid balloon valvuloplasty for management of severe mitral stenosis in four symptomatic, adult dogs. 62
35863126 2022
Renin-angiotensin-aldosterone system inhibition in patients affected by heart failure: efficacy, mechanistic effects and practical use of sacubitril/valsartan. Position Paper of the Italian Society of Cardiology. 62
35469709 2022
Haemolysis resolution after transcatheter valve in valve within a prior mitral annuloplasty ring: a case report. 62
36131810 2022
Incremental Utility of 3D Printing to Guide the Surgical Management of Apical Aneurysm. 62
36062049 2022
Valvular Heart Disease following Anthracycline Therapy-Is It Time to Look beyond Ejection Fraction? 62
36013454 2022
The Role of the Left Atrium: From Multimodality Imaging to Clinical Practice: A Review. 62
36013370 2022
Simulation of Mitral Valve Plasticity in Response to Myocardial Infarction. 62
36030332 2022
Complications of the Percutaneous Mitral Valve Edge-To-Edge Repair: Role of Transesophageal Echocardiography. 62
36012985 2022
Hypertrophic obstructive cardiomyopathy with a basal septal thickness of 16 mm or less: clinical characteristics and surgical results. 62
35079897 2022
Calculation of Mitral Valve Area by Continuity Equation Using Velocity-Time Integral From Mitral Valve Orifices After Mitral Clip. 62
35738563 2022
Early outcomes following transatrial transcatheter mitral valve replacement in patients with severe mitral annular calcification. 62
36153166 2022
Dynamic improvement of an acute exacerbated subaortic pressure gradient after intravenous propranolol and cibenzoline, recorded using a pressure wire: a case report. 62
35935397 2022
Robotic degenerative mitral repair: Factors associated with intraoperative revision and impact of mild residual regurgitation. 62
36182583 2022
Mitral valve replacement with papillary muscle tugging approximation in a patient with severely impaired left ventricular function 14 years after initial mitral valve repair. 62
35975225 2022
Shunt and pace: a novel experimental model of atrial fibrillation with a volume-loaded left atrium. 62
36031668 2022
Quantitative biomechanical optimization of neochordal implantation location on mitral leaflets during valve repair. 62
35967240 2022
Global longitudinal strain and outcome after endoscopic mitral valve repair. 62
35670015 2022
Significant Valvular Dysfunction and Outcomes in Cardiogenic Shock: Insights From the Randomized DOREMI Trial. 62
35430192 2022
Post-acute cardiac complications following SARS-CoV-2 infection in partial lipodystrophy due to LMNA gene p.R349W mutation. 62
35384599 2022
Myocardial fibrosis in asymptomatic patients undergoing surgery for mitral and aortic valve regurgitation. 62
35904996 2022
A rare left ventricular cardiac myxoma mimicking fibroma. 62
36028867 2022
Late Infective Endocarditis After Transcatheter Mitral Valve Reconstruction (MitraClip) :A Case Report and a Review of the Literature. 62
35938650 2022
Mid-term results of mitral valve reconstruction with autologous pericardial patch for active infective endocarditis with extensive leaflet destruction. 62
35138563 2022
Clinical profile and 90 day outcomes of 10 851 heart failure patients across India: National Heart Failure Registry. 62
36214477 2022
Challenge of a therapeutic sequence: rare case of heart failure in mitral valvular disease intensified by an extreme mediastinal shift from major diaphragmatic eventration. 62
35920785 2022
Prosthetic Mitral Valve Thrombosis: A Complication Following Mitral Valve Surgery and Coronary Artery Bypass Graft Surgery. 62
36134064 2022
Severe mitral regurgitation causing unilateral pulmonary edema: A case report. 62
35949571 2022
Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK. 62
35618104 2022
Cardiac magnetic resonance features and outcomes of patients with non-compaction cardiomyopathy - A retrospective follow-up from Pakistan. 62
35846858 2022
Modified chordal sparing mitral valve replacement as effective technique for both stenotic and insufficient mitral valves. 62
35848870 2022
Opposing forces of cardiogenic shock: left ventricular outflow obstruction, severe mitral regurgitation, and left ventricular dysfunction in Takotsubo cardiomyopathy. 62
35521673 2022
The leaflet-annulus index in canine myxomatous mitral valve disease. 62
36029573 2022
The outcome of surgical mitral valve repair with loop-in-loop technique in dogs with different stage myxomatous mitral valve disease. 62
35810732 2022
Venting during venoarterial extracorporeal membrane oxygenation. 62
35986750 2022
Unusual Change in Murmurs in a Case of Mitral Valve Prolapse. 62
36171823 2022
Concomitant mitral regurgitation in patients with low-gradient aortic stenosis: an analysis from the German Aortic Valve Registry. 62
35984497 2022
Prenatal aortic valvuloplasty as a definite treatment in fetuses with critical aortic stenosis, severe mitral regurgitation and giant left atrium: a report of two cases with medium-term follow-up. 62
35929437 2022
Left-Sided Degenerative Valvular Heart Disease in Type 1 and Type 2 Diabetes. 62
35678729 2022
Impact of Transcatheter Aortic Valve Implantation Among Patients With Co-existing Mild to Moderate Mitral Regurgitation. 62
35732551 2022
Deep Learning Electrocardiographic Analysis for Detection of Left-Sided Valvular Heart Disease. 62
35926935 2022
Barlow disease: effect of mitral valve repair on ventricular arrhythmias in 82 patients in a retrospective long-term study. 62
35588312 2022
Mitral valve plasty in a patient with multiple cerebral cavernous malformations: A case report. 62
36052025 2022
Microvascular Retinal Changes in Patients with Marfan Syndrome. 62
35416099 2022
A lightweight hybrid deep learning system for cardiac valvular disease classification. 62
35995814 2022
Cryopreserved aortic homografts for complex aortic valve or root endocarditis: a 28-year experience. 62
35388890 2022
Effect of mitral regurgitation on stroke risk in patients with non-rheumatic atrial fibrillation. 62
36030169 2022
Surgical treatment of patients with aortic valve disease complicated with moderate functional mitral regurgitation and heart failure with midrange ejection fraction: a cohort study. 62
36071759 2022
A successful double valve repair on an interesting background: Case report. 62
35526129 2022
Concurrent cardiac and central nervous system complications of acute infective endocarditis: case report. 62
36004042 2022
Potential efficacy of multipoint pacing in the reduction of mitral regurgitation volume: a case report. 62
35481626 2022
Nonischemic Super-Responders in Fusion CRT Pacing with Normal Atrioventricular Conduction. 62
36140434 2022
Temporal Changes in Cardiac Morphology and Its Relationship with Clinical Characteristics and Outcomes in Patients with Hypertrophic Cardiomyopathy. 62
35644698 2022
Mitral Regurgitation in Obstructive Hypertrophic Cardiomyopathy: Systolic Anterior Motion or a More Unusual Cause? 62
35183434 2022
Robotic mitral valve repair: A single center experience over a 7-year period. 62
35510407 2022
Successful transcatheter mitral valve repair with the MitraClip system in a patient with Duchenne muscular dystrophy. 62
35923537 2022
Handheld ultrasound as an adjunct to physical examination in the diagnosis of cardiopulmonary disease. 62
35543226 2022
TAVR for All? The Surgical Perspective. 62
35877585 2022
Effect of β-blocker on patients with moderate functional mitral regurgitation undergoing surgical aortic valve replacement. 62
35822509 2022
Systematic assessment of heart valves and cardiac function by echocardiography in axial spondyloarthritis: A systematic review and meta-analysis. 62
35259478 2022
Acute Mitral Regurgitation Due to Chordae Tendineae Rupture: A Rare Presentation of Cardiac Amyloidosis. 62
35781282 2022
Simplifying Mitral Valve Repair: A Guide to Neochordae Reconstruction. 62
35997684 2022
A Story of Two Tales: Behcet Disease Related Severe Aortic Regurgitation and Bacterial Endocarditis Associated Severe Mitral Regurgitation. 62
35873128 2022
All Endocarditis Is Not Infective: Libman-Sacks Endocarditis. 62
35936150 2022
Spontaneous Coronary Artery Dissection and Papillary Muscle Rupture in Patient With Undiagnosed Vascular Ehler-Danlos Syndrome. 62
35912327 2022
Practical Echocardiographic Approach of the Regurgitant Mitral Valve Assessment. 62
35885621 2022
Reasonable requests: echocardiography referral forms as a measure of coherent clinical communication. 62
35831886 2022
Cardiac Operations After Transcatheter Aortic Valve Replacement. 62
34800488 2022
National Trends and Outcomes of Surgical Aortic Valve Replacement With Concomitant Mitral Valve Surgery. 62
34801422 2022
Long-term cardiovascular safety of fenfluramine in patients with Dravet syndrome treated for up to 3 years: Findings from serial echocardiographic assessments. 62
35640431 2022
Closure of a patent ductus arteriosus in a 2-week-old llama cria using an Amplatz canine duct occluder. 62
35784772 2022
Which Findings Make multisystem Inflammatory Syndrome in Children Different from the Pre-Pandemic Kawasaki Disease? 62
35804239 2022
Anomalous origin of the left coronary artery from the pulmonary artery as a rare cause of mitral valve prolapse: a case report. 62
35788178 2022
Mitral valve chord rupture in a pregnant patient with uncontrolled hyperthyroidism. 62
35895699 2022
Interaction between secondary mitral regurgitation and left atrial function and their prognostic implications after cardiac resynchronization therapy. 62
35900222 2022
Mitral valve repair with patch augmentation for atrial functional mitral regurgitation complicated with giant left atrium. 62
35776257 2022
Echocardiographic description and outcomes in a heterogeneous cohort of patients undergoing mitral valve surgery with and without mitral annular disjunction: a health service evaluation. 62
35821076 2022
Flow adjusted transmitral pressure gradient as a modified indicator of functional mitral stenosis after repair for degenerative mitral regurgitation. 62
35234318 2022
Guideline-directed medical therapy in patients undergoing transcatheter edge-to-edge repair for secondary mitral regurgitation. 62
35791663 2022
Speckle tracking echocardiography in primary mitral regurgitation: should we reconsider the time for intervention? 62
33829389 2022
A rare congenital anomaly: Anomalous fibromuscular cord of the left atrium. 62
35470914 2022
A Case of Ruptured Giant Sinus of Valsalva Aneurysm Into the Right Ventricle in a Patient With Both Atrial and Ventricular Septal Defects. 62
34887201 2022
Transcatheter edge-to-edge valve repair in functional mitral regurgitation. 62
34893809 2022
Surgical Outcomes for Children with Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery. 62
35799066 2022
Unexpected systolic anterior motion of the mitral valve-related hypoxemia during transurethral resection of the prostate under spinal anesthesia: a case report. 62
35794519 2022
Prevalence and determinants of atrial fibrillation progression in paroxysmal atrial fibrillation. 62
35858774 2022
Durable Robotic Mitral Repair of Degenerative Primary Regurgitation With Long-Term Follow-Up. 62
34437853 2022
Mitral valve replacement through mini sternotomy after long ECMO course: Case report. 62
33779404 2022
Cardiac involvement in multisystem inflammatory syndrome in children: single-centre experience. 62
35837680 2022
Management Challenge: An Atypical Variant of Takotsubo Presenting With Multiple Complications. 62
35854952 2022
Acute mitral valve regurgitation secondary to papillary muscle rupture due to infective endocarditis. 62
35804449 2022
Dissection of anterior mitral valve leaflet masking severe mitral regurgitation - an unusual case of infective endocarditis. 62
34254881 2022
Predicting outcome after cardiac resynchronisation therapy defibrillator implantation: the cardiac resynchronisation therapy defibrillator Futility score. 62
35410895 2022
Mitral and aortic valve regurgitation following surgical and transcatheter perimembranous ventricular septal defect closure in children and adolescents: midterm outcomes. 62
35840901 2022
Left atrial volume index and outcome after transcatheter edge-to-edge valve repair for secondary mitral regurgitation. 62
35642951 2022
A Case of Antiphospholipid Syndrome Nephropathy related Disease Diagnosed by Assessing Phosphatidylserine-dependent Antiprothrombin Antibodies. 62
35908966 2022
Double right coronary artery with fistula to the right atrium and mitral insufficiency: A case report. 62
35810684 2022
Calcification of Gore-Tex Neochord After Mitral Repair: Electron Microscopy. 62
34599910 2022
Catheter-Based Management of Heart Failure: Pathophysiology and Contemporary Data. 62
35710282 2022
Clinical Characteristics of Non-Valvular Atrial Fibrillation Patients With a Large Left Atrial Appendage Ostium-Limiting Percutaneous Closure. 62
35786689 2022
Remodelling is inversely proportional to left ventricular dimensions in a real-life population of patients with chronic heart failure after therapy with sacubitril/valsartan. 62
34353236 2022
Intraoperative echocardiographic assessment of mitral valve translocation. 62
35277715 2022
Minimally invasive mitral valve surgery after failed transcatheter mitral valve repair in an intermediate-risk cohort. 62
35713519 2022
Management of Atrial Fibrillation Across the Spectrum of Heart Failure With Preserved and Reduced Ejection Fraction. 62
35877831 2022
[Robot-assisted Cardiac Surgery Council and Current Status and Future Prospect of Robotic Mitral Valve Surgery in Japan]. 62
35799482 2022
Gender difference in outcomes of patients undergoing MitraClip therapy: A systematic review and meta-analysis. 62
34799289 2022
[Early Experience of Robot-assisted Mitral Valve Surgeries in Our Local Hospital]. 62
35799493 2022
Functional tricuspid regurgitation, related right heart remodeling, and available treatment options: good news for patients with heart failure? 62
34264478 2022
Closed Mitral Valvotomy Reenvision. 62
36046295 2022
Tolerability of Sacubitril/Valsartan in Patients With Advanced Heart Failure: Analysis of the LIFE Trial Run-In. 62
35772853 2022
Repair of Anomalous Single Coronary Artery From the Pulmonary Artery (ASCAPA). 62
34928744 2022
Left Atrial Filling Time Index (LAFTI) Evaluated by 2D Speckle Tracking Echocardiography Predicts Poor Cardiac Prognosis in Patients with Heart Failure. 62
35831143 2022
The Road to a Transcatheter Edge to Edge Repair: Patient Experiences Leading Up to the Procedure and in the Early Recovery Period. 62
35895525 2022
The Prognostic Role of Mitral Valve Regurgitation Severity and Left Ventricle Function in Acute Heart Failure. 62
35893359 2022
Periareolar endoscopic minimally invasive cardiac surgery: postoperative scar assessment analysis. 62
35863058 2022
Early and late results of mitral valve repair with anterior leaflet patch augmentation. 62
35640545 2022
Clinical Outcomes of Mitral Valve Disease With Mitral Annular Calcification. 62
35450733 2022
Three-Dimensional Endoscopic-Assisted Concomitant Mitral and Aortic Valve Surgery. 62
34798075 2022
Stress Echocardiography After Mitral Valve Repair Using a Semirigid Partial Band. 62
34480894 2022
Dynamics of Cognitive Function in Patients with Heart Failure Following Transcatheter Mitral Valve Repair. 62
35887753 2022
Mitral valve surgery after failed MitraClip-Operation for the inoperable? 62
35842819 2022
Institution representation in publications reporting mitral valve repair durability: A scoping review. 62
35506749 2022
Simultaneous transcatheter tricuspid and mitral valve-in-valve replacement for the treatment of degenerated bioprosthetic valves. 62
35393681 2022
Were they inoperable? Really? 62
35842818 2022
Meta-Analysis of Relation Between Left Ventricular Dysfunction and Outcomes After Transcatheter Mitral Edge-to-Edge Repair. 62
35550821 2022
Esophageal Submucosal Giant Hematoma Detected After Mitral Repair Using Transesophageal Echocardiography. 62
36039225 2022
Patient-Specific Three-Dimensional Ultrasound Derived Computational Modeling of the Mitral Valve. 62
35380321 2022
Long-term outcomes in distinct phenogroups of patients with primary mitral regurgitation undergoing valve surgery. 62
35882521 2022
Transcatheter Mitral Valve Repair in Patients With Atrial Functional Mitral Regurgitation. 62
35842361 2022
Mitral Regurgitation and Serum N-Terminal Pro-Brain Natriuretic Peptide Levels in Children: A Modification of Adult Criteria. 62
36037436 2022
Left Atrial Remodeling after Mitral Valve Repair for Primary Mitral Regurgitation: Evolution over Time and Prognostic Significance. 62
35877592 2022
Prognostic value of left ventricular global longitudinal strain in mitral regurgitation: a systematic review. 62
35900680 2022
Transcatheter edge-to-edge mitral valve repair in mitral regurgitation: current status and future prospects. 62
35791872 2022
MitraClip as Last-Resort Interventional Therapy for Refractory Mitral Regurgitation After Complete Revascularization for Acute Myocardial Infarction. 62
35860348 2022
How Can We Improve Long-Term Surgical Outcomes in Patients With Ischemic Mitral Regurgitation and Cardiomyopathy? 62
34582757 2022
Transcatheter therapies for secondary mitral regurgitation in advanced heart failure: what are we aiming for? 62
34291400 2022
Commentary: Cause or consequence? The influence of mitral regurgitation on post-myocardial infarction structural remodeling is better defined using a new rodent model. 62
31610958 2022
Mitral Regurgitation-When One View Isn't Enough. 62
35370075 2022
Coaptation Reserve Predicts Optimal Reduction in Mitral Regurgitation and Long-Term Survival With Transcatheter Edge-to-Edge Repair. 62
35686547 2022
MitraClip for secondary mitral regurgitation: Patient selection. 62
35605697 2022
Treatment of secondary mitral regurgitation by transcatheter edge-to-edge repair using MitraClip. 62
35708872 2022
Atrial functional mitral regurgitation: A cautionary tale? 62
35819151 2022
Early Outcomes of Endoscopic Papillary Muscle Relocation for Secondary Mitral Regurgitation Type IIIb in Patients With Severe Left Ventricular Dysfunction. 62
35983699 2022
Passive mechanical properties of the left ventricular myocardium and extracellular matrix in hearts with chronic volume overload from mitral regurgitation. 62
35871778 2022
Anomalous left atrial chorda and its association with mitral regurgitation. 62
35799572 2022
Transcatheter edge-to-edge repair for acute mitral regurgitation with cardiogenic shock secondary to mechanical complication. 62
35882600 2022
Myocardial Contractile Mechanics in Ischemic Mitral Regurgitation: Multicenter Data Using Stress Perfusion Cardiovascular Magnetic Resonance. 62
35798397 2022
Comparison of Mitral Regurgitant Volume Assessment between Proximal Flow Convergence and Volumetric Methods in Patients with Significant Primary Mitral Regurgitation: An Echocardiographic and Cardiac Magnetic Resonance Imaging Study. 62
35288306 2022
Ischemia, Wall Motion, and Functional Mitral Regurgitation: Getting to the Heart of the Matter. 62
35798398 2022
Atrial mitral regurgitation: Characteristics and outcomes of transcatheter mitral valve edge-to-edge repair. 62
35535629 2022
Clinical Outcomes After Durable Mitral Valve Repair for Ischemic Mitral Regurgitation. 62
34534528 2022
Garden-Hose Mitral Regurgitation: A Variant That Can Result in Underestimation of Severity: A Multimodality Imaging Case Study. 62
35397959 2022
Insights from a clinical heart valve centre: characteristics and management of functional mitral regurgitation. 62
35791723 2022
Transcatheter Treatment of Tricuspid and Mitral Regurgitation: Similar Path, Different Stages. 62
34906439 2022
QCA to Guide Treatment of Inter-Clip Mitral Regurgitation Between Two Previously Implanted MitraClips. 62
34059465 2022
Recurrent acute pulmonary oedema in a patient with a calcified cardiac tumour and mitral regurgitation: a new frontier for percutaneous mitral valve repair. 62
35673275 2022
Combination of the Modified Loop Technique and De Vega Annuloplasty in Dogs with Mitral Regurgitation. 62
35804552 2022
Treating Mitral Regurgitation at the Ventricular Level: Is it the Right Solution? 62
35738746 2022
Leaflet Resection vs Preservation for Degenerative Mitral Regurgitation: Functional Outcomes and Mitral Stenosis at 12 Months in a Randomized Trial. 62
35074417 2022
The Landscape of Primary Mitral Regurgitation Phenotypes: Smoothing the Terrain. 62
35680230 2022
Response to: Correspondence on 'Cost-effectiveness of transcatheter edge-to-edge repair in secondary mitral regurgitation does need confirmation' by Armoiry and Connock. 62
35534052 2022
Response to: Correspondence on 'Cost-effectiveness of transcatheter edge-to-edge repair in secondary mitral regurgitation does need confirmation' by Armoiry and Connock. 62
35534049 2022
Two-year outcome after standardized papillary muscle relocation for type IIIb secondary mitral regurgitation: is it enough to assess the result improvement? 62
35678572 2022
A Hybrid Intervention for Post-infarction Papillary Muscle Rupture with Severe Mitral Regurgitation: A Case Report. 62
35292600 2022
Network Analysis of Cardiac Remodeling by Primary Mitral Regurgitation Emphasizes the Role of Diastolic Function. 62
35680229 2022
Surgical revision of failed MitraClip procedure for atrial functional mitral regurgitation. 62
34056668 2022
Mitral Regurgitation in Heart Failure: Does it Raise Risk for Atrial Fibrillation More in HfpEF Than in HFrEF? 62
34936897 2022
Subannular repair or transcatheter edge-to-edge repair for secondary mitral regurgitation? More data for international guidelines. 62
36004223 2022
Grading mitral regurgitation using 4D flow CMR: Comparison to transthoracic echocardiography. 62
35536700 2022
Usability, performance and safety of a new device for degenerative mitral regurgitation: in vivo chronic evaluation. 62
35289855 2022
Prevalence of sleep-disordered breathing in patients with mitral regurgitation and the effect of mitral valve repair. 62
35725864 2022
Corrigendum to 'Relation of Guideline Adherence to Outcomes in Patients With Asymptomatic Severe Primary Mitral Regurgitation' [The American Journal of Cardiology 155 (2021) 113-120]. 62
35422327 2022
A Case of Transient Mitral Regurgitation: Not Everything Is Always What It Seems. 62
34972611 2022
Commissural closure to treat severe mitral regurgitation: standing the test of time. 62
35278069 2022
In HF with mitral regurgitation, adding transcatheter mitral valve repair to medical therapy improved renal outcomes at 2 y. 62
35667071 2022
Edge-to-edge percutaneous mitral repair for functional ischaemic and non-ischaemic mitral regurgitation: a systematic review and meta-analysis. 62
35770326 2022
Intraoperative transesophageal echocardiography reveals diastolic mitral regurgitation caused by an aortic regurgitation jet. 62
35748979 2022
Impact of ischemia on left atrial remodeling and dysfunction in swine models of mitral regurgitation. 62
35333115 2022
Isometric Handgrip Stress Test during Right Heart Catheterization in Patients with Mitral Regurgitation -A Case Series Study. 62
34776492 2022
Not Your "Run-of-the-Mill" Mitral Regurgitation. 62
35221221 2022
Correspondence on 'Cost-effectiveness of transcatheter edge-to-edge repair in secondary mitral regurgitation does need confirmation' by Cohen et al. 62
35534051 2022
Guideline directed medical therapy and reduction of secondary mitral regurgitation. 62
35466372 2022
Optimization of guideline-directed medical treatment to reduce secondary mitral regurgitation: treat the ventricle, not only the valve. 62
35466373 2022
Standardized papillary muscle relocation for type IIIb secondary mitral regurgitation improves 2-year outcome. 62
35511127 2022
Neochord DS1000 system versus conventional mitral valve repair for correction of mitral regurgitation due to prolapse of the posterior leaflet. 62
35639949 2022
Impact of prosthesis-patient mismatch on late outcomes after bioprosthetic mitral valve replacement for mitral regurgitation. 62
34665354 2022
Transapical beating heart mitral valve repair versus conventional surgery: a propensity-matched study. 62
35234902 2022
Mitral valve repair for extreme billowing and prolapsing valve. 62
36004259 2022
Predicting major events in ambulatory patients with advanced heart failure awaiting heart transplantation: a pilot study. 62
35645029 2022
Mitral Repair With Complete Rings or Posterior Bands in Barlow Disease: Long-term Results. 62
35780815 2022
Restrictive annuloplasty on remodeling and survival in patients with end-stage ischemic cardiomyopathy. 62
35811142 2022
Risk Factors for Postrepair Elevated Mitral Gradient: A Post-hoc Analysis of a Randomized Trial. 62
35779599 2022
36026978 2022
Hemolytic Anemia After Surgical Mitral Valve Repair Treated With Transcatheter Edge-to-Edge Device. 62
35734523 2022
Beyond the 10-Year Horizon: Mitral Valve Repair Solely With Chordal Replacement and Annuloplasty. 62
35690138 2022
Iberian experience with PASCAL transcatheter edge-to-edge repair for mitral valve regurgitation. 62
35691867 2022
Transcatheter, Transapical Mitral Valve Replac