MCID: APM001
MIFTS: 15

Aapoaii Amyloidosis

Categories: Bone diseases, Genetic diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Aapoaii Amyloidosis

MalaCards integrated aliases for Aapoaii Amyloidosis:

Name: Aapoaii Amyloidosis 58
Hereditary Amyloid Nephropathy Due to Apolipoprotein a-Ii Variant 58
Familial Amyloid Nephropathy Due to Apolipoprotein a-Ii Variant 58
Hereditary Renal Amyloidosis Due to Apolipoprotein a-Ii Variant 58
Familial Renal Amyloidosis Due to Apolipoprotein a-Ii Variant 58
Apolipoprotein a-Ii Amyloidosis 58

Characteristics:

Orphanet epidemiological data:

58
aapoaii amyloidosis
Inheritance: Autosomal dominant;

Classifications:

Orphanet: 58  
Rare renal diseases
Rare systemic and rhumatological diseases


External Ids:

ICD10 via Orphanet 33 E85.0
Orphanet 58 ORPHA238269

Summaries for Aapoaii Amyloidosis

MalaCards based summary : Aapoaii Amyloidosis, also known as hereditary amyloid nephropathy due to apolipoprotein a-ii variant, is related to amyloidosis, familial visceral and amyloidosis. An important gene associated with Aapoaii Amyloidosis is APOA2 (Apolipoprotein A2). Affiliated tissues include bone, heart and skeletal muscle.

Related Diseases for Aapoaii Amyloidosis

Diseases related to Aapoaii Amyloidosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 amyloidosis, familial visceral 11.5
2 amyloidosis 10.7

Symptoms & Phenotypes for Aapoaii Amyloidosis

Drugs & Therapeutics for Aapoaii Amyloidosis

Search Clinical Trials , NIH Clinical Center for Aapoaii Amyloidosis

Genetic Tests for Aapoaii Amyloidosis

Anatomical Context for Aapoaii Amyloidosis

MalaCards organs/tissues related to Aapoaii Amyloidosis:

40
Bone, Heart, Skeletal Muscle, Kidney, Liver, Lung

Publications for Aapoaii Amyloidosis

Articles related to Aapoaii Amyloidosis:

(show all 18)
# Title Authors PMID Year
1
Suppression of Mouse AApoAII Amyloidosis Progression by Daily Supplementation with Oxidative Stress Inhibitors. 61
31281565 2019
2
Amyloidosis-inducing activity of blood cells in mouse AApoAII amyloidosis. 61
29081441 2018
3
Comprehensive proteomic profiles of mouse AApoAII amyloid fibrils provide insights into the involvement of lipoproteins in the pathology of amyloidosis. 61
28988881 2018
4
Caloric restriction prevents the progression of murine AApoAII amyloidosis. 61
28434314 2017
5
Caloric restriction reduces the systemic progression of mouse AApoAII amyloidosis. 61
28225824 2017
6
Extracellular deposition of mouse senile AApoAII amyloid fibrils induced different unfolded protein responses in the liver, kidney, and heart. 61
25545477 2015
7
[Can prion-like propagation occur in neurodegenerative diseases?: in view of transmissible systemic amyloidosis]. 61
22647474 2012
8
ApoA-I deficiency in mice is associated with redistribution of apoA-II and aggravated AApoAII amyloidosis. 61
21622630 2011
9
Mouse senile amyloid fibrils deposited in skeletal muscle exhibit amyloidosis-enhancing activity. 61
20502680 2010
10
Cross-seeding and cross-competition in mouse apolipoprotein A-II amyloid fibrils and protein A amyloid fibrils. 61
17591964 2007
11
Transmissibility of mouse AApoAII amyloid fibrils: inactivation by physical and chemical methods. 61
16549653 2006
12
Transmission of amyloidosis in offspring of mice with AApoAII amyloidosis. 61
16507905 2006
13
Acceleration of murine amyloidosis by implantation of amyloid-containing grafts. 61
16399647 2005
14
Induction of AApoAII amyloidosis by various heterogeneous amyloid fibrils. 61
15063745 2004
15
Amyloidosis modifier genes in the less amyloidogenic a/j mouse strain. 61
14615414 2003
16
Transmission of mouse senile amyloidosis. 61
11304568 2001
17
Lung, ileum and heart are predilection sites for AApoAII amyloid deposition in CD-1 Swiss mice used for toxicity studies. Pulmonary amyloid indicates AApoAII. 61
8709570 1996
18
Gastrointestinal AAPOAII and systemic AA-amyloidosis in aged C57BL/Ka mice. Amyloid-type dependent effect of long-term immunosuppressive treatment. 61
8401815 1993

Variations for Aapoaii Amyloidosis

Expression for Aapoaii Amyloidosis

Search GEO for disease gene expression data for Aapoaii Amyloidosis.

Pathways for Aapoaii Amyloidosis

GO Terms for Aapoaii Amyloidosis

Sources for Aapoaii Amyloidosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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