Abdominal Obesity-Metabolic Syndrome 4 (AOMS4)

External Ids:

OMIM 56 618620 OMIM Phenotypic Series 56 PS605552

MeSH 43 D024821

OMIM : ⁵⁶ Abdominal obesity-metabolic syndrome-4 (AOMS4) is characterized by obesity, hypertension, and early-onset coronary artery disease. Most affected individuals meet the criteria for metabolic syndrome, including elevated triglyceride and low high-density lipoprotein levels, and type 2 diabetes (Esteghamat et al., 2019). For a discussion of the genetic heterogeneity of abdominal obesity-metabolic syndrome, see AOMS1 (605552). (618620)

MalaCards based summary : Abdominal Obesity-Metabolic Syndrome 4, is also known as aoms4. An important gene associated with Abdominal Obesity-Metabolic Syndrome 4 is CELA2A (Chymotrypsin Like Elastase 2A).

UniProtKB/Swiss-Prot : ⁷³ Abdominal obesity-metabolic syndrome 4: A form of abdominal obesity-metabolic syndrome, a disorder characterized by abdominal obesity, high triglycerides, low levels of high density lipoprotein cholesterol, high blood pressure, and elevated fasting glucose levels. AOMS4 is an autosomal dominant disease. Patients manifest obesity, hypertension, early-onset coronary artery disease and type 2 diabetes.

Clinical features from OMIM:

618620

Search Clinical Trials , NIH Clinical Center for Abdominal Obesity-Metabolic Syndrome 4

Search GEO for disease gene expression data for Abdominal Obesity-Metabolic Syndrome 4.