MCID: ABD004
MIFTS: 39

Abdominal Tuberculosis

Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases

Aliases & Classifications for Abdominal Tuberculosis

MalaCards integrated aliases for Abdominal Tuberculosis:

Name: Abdominal Tuberculosis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050599

Summaries for Abdominal Tuberculosis

Disease Ontology : 12 An extrapulmonary tuberculosis that is located in gastrointestinal tract, located in peritoneum, located in omentum, located in mesentery, located in liver, located in spleen or located in pancreas.

MalaCards based summary : Abdominal Tuberculosis is related to splenic tuberculosis and mycobacterium tuberculosis 1. An important gene associated with Abdominal Tuberculosis is IL12RB1 (Interleukin 12 Receptor Subunit Beta 1), and among its related pathways/superpathways are 4-1BB Pathway and Th17 cell differentiation. The drugs Antitubercular Agents and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include gastrointestinal tract, peritoneum and omentum.

Wikipedia : 73 Abdominal tuberculosis is a type of extrapulmonary tuberculosis which involves the abdominal organs such... more...

Related Diseases for Abdominal Tuberculosis

Diseases related to Abdominal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 685)
# Related Disease Score Top Affiliating Genes
1 splenic tuberculosis 31.0 F2 CRP CEACAM5 CD4 ALB ADA
2 mycobacterium tuberculosis 1 30.9 TNF IL12RB1 IFNG CD4 ADA
3 extrapulmonary tuberculosis 30.9 IFNG CRP ADA
4 peritonitis 30.8 TNF F2 CRP ALB ADA
5 pulmonary tuberculosis 30.5 TNF IL12RB1 IFNG ALB ADA
6 ileus 30.3 TNF F2 CRP
7 intestinal obstruction 30.2 TNF GPT CRP CEACAM5 ALB
8 lymphadenitis 30.2 TNF IL12RB1 IFNG CRP CD4
9 portal vein thrombosis 30.1 F2 CRP AFP
10 intracranial sinus thrombosis 30.1 F2 CRP
11 hemopericardium 30.1 F2 CRP
12 crohn's disease 30.1 TNF IFNG CRP CD4 ALB
13 tuberculous peritonitis 30.1 TBP IFNG CRP CEACAM5 ALB ADA
14 diarrhea 30.0 TNF IFNG GPT ALB
15 optic papillitis 30.0 CRP CD4
16 active peptic ulcer disease 30.0 F2 CRP ALB
17 intestinal tuberculosis 30.0 TNF MIR4659A IFNG CRP CD4 ALB
18 appendicitis 30.0 TNF IFNG CRP ALB
19 constrictive pericarditis 30.0 IFNG CRP ALB ADA
20 constipation 29.9 TNF GPT CRP ALB
21 duodenal obstruction 29.9 CRP CEACAM5 ALB
22 osteomyelitis 29.8 TNF IFNG CRP
23 adult-onset still's disease 29.8 TNF IFNG CRP
24 reactive arthritis 29.8 TNF IFNG CRP
25 choroiditis 29.8 TNF IFNG CD4
26 portal hypertension 29.8 TNF GPT F2 CD4 ALB
27 acquired immunodeficiency syndrome 29.7 TNF IFNG CRP CD4 ALB ADA
28 anal fistula 29.7 TNF CRP AFP
29 intestinal perforation 29.7 TNF GPT CRP CD4 ALB
30 acute pancreatitis 29.7 TNF GPT CRP
31 pericarditis 29.6 TNF IFNG CRP ALB ADA
32 pleurisy 29.6 TNF IFNG CRP ADA
33 gastroenteritis 29.6 TNF IFNG CRP ALB
34 histoplasmosis 29.6 TNF IL12RB1 IFNG CD4
35 multidrug-resistant tuberculosis 29.6 TNF IFNG CD4 ALB
36 lymph node tuberculosis 29.5 TNF IFNG CRP CD4
37 obstructive jaundice 29.5 TNF GPT F2 CRP ALB
38 panniculitis 29.5 TNF IFNG CRP CD4
39 splenic infarction 29.5 GPT F2 CRP ALB
40 gastrointestinal tuberculosis 29.5 TNF TBP MIR4659A IFNG GPT CRP
41 non-alcoholic steatohepatitis 29.5 TNF GPT ALB
42 inflammatory bowel disease 29.5 TNF IL12RB1 IFNG F2 CRP ALB
43 hemolytic anemia 29.5 TNF IFNG F2 ADA
44 splenic abscess 29.5 GPT F2 CRP CD4 ALB
45 human immunodeficiency virus type 1 29.4 TNF IFNG CD4 ADA
46 miliary tuberculosis 29.4 TNF IL12RB1 IFNG CRP CD4 ALB
47 nocardiosis 29.4 TNF IL12RB1 IFNG CRP CD4
48 granulomatous hepatitis 29.3 TNF GPT CRP CD4 ALB
49 lymph node disease 29.3 TNF IFNG CRP CD4 ALB
50 hepatitis 29.2 TNF IFNG GPT F2 AFP

Graphical network of the top 20 diseases related to Abdominal Tuberculosis:



Diseases related to Abdominal Tuberculosis

Symptoms & Phenotypes for Abdominal Tuberculosis

Drugs & Therapeutics for Abdominal Tuberculosis

Drugs for Abdominal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 3
2
Triamcinolone Approved, Vet_approved 124-94-7 31307
3 Triamcinolone diacetate
4 Triamcinolone hexacetonide
5 triamcinolone acetonide

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Multi-centric Study on Treatment of Abdominal Tuberculosis (Intestinal or Peritoneal): A Randomized Controlled Trial to Compare the 6 Months of Cat I Treatment With 9 Months of Cat I Treatment (Extension for 3 Months) in Abdominal Tuberculosis Under the Revised National Tuberculosis Control Program Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months
2 Professor and Head of Department of Surgery Dow University Hospital DUHS Completed NCT04065607
3 Acute Presentation and Management of Abdominal Tuberculosis: A Ten-year Experience at a Tertiary Care Center in Pakistan Completed NCT03918226

Search NIH Clinical Center for Abdominal Tuberculosis

Genetic Tests for Abdominal Tuberculosis

Anatomical Context for Abdominal Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Abdominal Tuberculosis:

19
Gastrointestinal Tract, Peritoneum, Omentum, Mesentery, Liver, Spleen, Pancreas

MalaCards organs/tissues related to Abdominal Tuberculosis:

40
Liver, Spleen, Pancreas, Heart, Lung, Ovary, Skin

Publications for Abdominal Tuberculosis

Articles related to Abdominal Tuberculosis:

(show top 50) (show all 847)
# Title Authors PMID Year
1
Pediatric Abdominal Tuberculosis With Calcified Intra-abdominal Lymph Nodes Identified by Point-of-Care Ultrasound. 61
33780407 2021
2
Diagnostic accuracy of the Xpert MTB/RIF assay for abdominal tuberculosis: a systematic review and meta-analysis. 61
32845790 2021
3
TB or not TB: A comprehensive review of imaging manifestations of abdominal tuberculosis and its mimics. 61
33596517 2021
4
An unusual case of seizures in a 5-year-old Syrian female with abdominal tuberculosis: an isoniazid therapeutic dose side effect. 61
33542828 2021
5
Gastroduodenal tuberculosis: a case series and a management focused systematic review. 61
32878489 2021
6
Intestinal Tuberculosis Presenting as an Ileocecal Mass in a Renal Transplant Patient. 61
33659129 2021
7
Abdominal Tuberculosis Complicated by Intestinal Perforation. 61
33628536 2021
8
A rare case of abdominal tuberculosis. 61
33294088 2021
9
Abdominal Tuberculosis: Experience from Two Tertiary-Care Hospitals in the Paris Region. 61
33205739 2021
10
CA 125 and TB. 61
33462021 2021
11
Acute appendicitis in people living with HIV: What does the emergency surgeon needs to know? 61
33614033 2021
12
Thinking Outside the Lungs: A Case of Disseminated Abdominal Tuberculosis. 61
33239604 2020
13
Gastrointestinal trichobezoar: An experience with 17 cases. 61
32467033 2020
14
Abdominal Involvement in Children With Bacteriologically Confirmed Tuberculosis: A Five-year Experience From Cape Town, South Africa. 61
32496408 2020
15
Complexities of an uncomplicated symptom: two cases of umbilical discharge. 61
32907865 2020
16
Clinical Spectrum and Medical Comorbidities in Tuberculosis: A Hospital-Based Study in Northeast India. 61
33110716 2020
17
[How I explore … abdominal tuberculosis in children ?] 61
32909415 2020
18
Xpert MTB/RIF for diagnosis of tubercular liver abscess. A case series. 61
32920579 2020
19
Abdominal tuberculosis in Ecuador, a problem that is still not solved. 61
32637658 2020
20
Abdominal Tuberculosis Mimicking Ovarian Cancer: A Diagnostic Dilemma. 61
32764852 2020
21
Extra-central nervous system tuberculosis in HIV-uninfected patients of tuberculous meningitis: A prospective evaluation. 61
32439354 2020
22
Evaluation of Twenty-One Cases of Abdominal Tuberculosis: A Single-Center Experience. 61
32697624 2020
23
Hodkgin lymphoma concomitant of tuberculosis, a therapeutic challenge for multidisciplinary management. 61
32444284 2020
24
Abdominal Tuberculosis in Children: Is It Really Uncommon? 61
32844820 2020
25
Coinfection of Typhoid Fever With Tuberculosis: A Challenge to Surgical Management. 61
32670677 2020
26
Abdominal Tuberculosis in Children: Challenges, Uncertainty, and Confusion. 61
31909804 2020
27
Tuberculosis of the gallbladder-another one of its many faces. 61
32553321 2020
28
Gallbladder tuberculosis in a dialysis patient: a case-report. 61
32264878 2020
29
Abdominal tuberculosis in children: A real-world experience of 218 cases from an endemic region. 61
32280767 2020
30
Abdominal Tuberculosis Managed Surgically in the Late Phase: A Case Report. 61
32995153 2020
31
Tuberculosis and the Acute Abdomen: An Evaluation of the National Inpatient Sample. 61
31464571 2020
32
Systemic Melioidosis with Acute Osteomyelitis and Septic Arthritis Misdiagnosed as Tuberculosis: A Case Report. 61
32211247 2020
33
Abdominal Tuberculosis Mimicking Cancer Clinically and on Fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET) Imaging: A Two-Case Series. 61
32019906 2020
34
Acute Presentation and Management of Abdominal Tuberculosis. 61
32036817 2020
35
18F-FDG PET-CT Diagnosis of Tuberculosis in Celiac Lymph Nodes. 61
33293851 2020
36
Defining 'Satisfactory Response' to Therapy in Abdominal Tuberculosis: A Work in Progress. 61
30345933 2020
37
Meta-analysis of diagnostic accuracy of nucleic acid amplification tests for abdominal tuberculosis: A protocol. 61
33315919 2020
38
Pediatric Abdominal Tuberculosis in Singapore: A 10-Year Retrospective Series. 61
32076630 2020
39
Case report demonstrating abdominal tuberculosis presenting as an irreducible para-umbilical hernia. 61
32919333 2020
40
The initial intravenous treatment of a human immunodeficiency virus-infected child with complicated abdominal tuberculosis. 61
32934837 2020
41
Utility of circulating cell-free Mycobacterium tuberculosis DNA for the improved diagnosis of abdominal tuberculosis. 61
32845896 2020
42
Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Imagıng in Pseudo Sister Mary Joseph's Nodule. 61
31949374 2020
43
Diagnostic Value of T-SPOT.TB Assay for Tuberculous Peritonitis: A Meta-Analysis. 61
33425937 2020
44
Natural course of diffuse large B cell lymphoma-a manifestation in buccal mucosa. 61
31842892 2019
45
Intra-abdominal tuberculosis masquerading as ovarian carcinoma. 61
31890148 2019
46
GeneXpert in stool: Diagnostic yield in Intestinal Tuberculosis. 61
31788572 2019
47
Chronic constrictive pericarditis complicated with huge right atrial thrombus in a child with abdominal tuberculosis: a rare life-threatening condition. 61
31723400 2019
48
Poncet's disease in an adolescent with abdominal tuberculosis. 61
29897290 2019
49
[Difficulties and mistakes in the diagnosis of abdominal tuberculosis in the practice of the general practitioner]. 61
32598604 2019
50
[Treatment of abdominal tuberculosis : Background, diagnostics and treatment of a global problem]. 61
31321450 2019

Variations for Abdominal Tuberculosis

Expression for Abdominal Tuberculosis

Search GEO for disease gene expression data for Abdominal Tuberculosis.

Pathways for Abdominal Tuberculosis

Pathways related to Abdominal Tuberculosis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.42 TNF TBP IFNG CD4
2
Show member pathways
12.33 TNF IL12RB1 IFNG CD4
3
Show member pathways
12.3 TNF IL12RB1 IFNG F2 CD4
4
Show member pathways
11.74 IL12RB1 IFNG CD4
5
Show member pathways
11.69 TNF IFNG F2 CRP ALB
6 11.62 TNF IFNG CEACAM5 CD4
7
Show member pathways
11.61 IL12RB1 IFNG CD4
8 11.55 TBP IFNG AFP
9 11.48 TNF IFNG CD4
10 11.36 TNF IL12RB1 IFNG CD4
11 11.22 F2 ALB AFP
12 10.96 TNF IFNG CD4
13
Show member pathways
10.81 TNF IL12RB1 IFNG CD4

GO Terms for Abdominal Tuberculosis

Cellular components related to Abdominal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.56 TNF IFNG GPT F2 CRP ALB
2 endoplasmic reticulum lumen GO:0005788 9.46 F2 CD4 ALB AFP
3 external side of plasma membrane GO:0009897 9.02 TNF IL12RB1 F2 CD4 ADA

Biological processes related to Abdominal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.56 TNF IFNG F2 CD4
2 embryonic digestive tract development GO:0048566 9.48 TNF ADA
3 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.46 TNF IFNG
4 positive regulation of calcium-mediated signaling GO:0050850 9.43 CD4 ADA
5 astrocyte activation GO:0048143 9.4 TNF IFNG
6 negative regulation of amyloid-beta clearance GO:1900222 9.37 TNF IFNG
7 negative regulation of lipid storage GO:0010888 9.32 TNF CRP
8 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.16 TNF IFNG
9 positive regulation of vitamin D biosynthetic process GO:0060557 8.96 TNF IFNG
10 positive regulation of nitrogen compound metabolic process GO:0051173 8.62 TNF IFNG

Sources for Abdominal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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