MCID: ACC008
MIFTS: 9

Accelerated Tumor Formation

Categories: Genetic diseases

Aliases & Classifications for Accelerated Tumor Formation

MalaCards integrated aliases for Accelerated Tumor Formation:

Name: Accelerated Tumor Formation 57
Accelerated Tumor Formation, Susceptibility to 57 29 13 6
Tumor Formation, Accelerated, Susceptibility to 40
Actfs 57

Classifications:



External Ids:

OMIM 57 614401

Summaries for Accelerated Tumor Formation

MalaCards based summary : Accelerated Tumor Formation, is also known as accelerated tumor formation, susceptibility to. An important gene associated with Accelerated Tumor Formation is MDM2 (MDM2 Proto-Oncogene).

Description from OMIM: 614401

Related Diseases for Accelerated Tumor Formation

Symptoms & Phenotypes for Accelerated Tumor Formation

Clinical features from OMIM:

614401

Drugs & Therapeutics for Accelerated Tumor Formation

Search Clinical Trials , NIH Clinical Center for Accelerated Tumor Formation

Genetic Tests for Accelerated Tumor Formation

Genetic tests related to Accelerated Tumor Formation:

# Genetic test Affiliating Genes
1 Accelerated Tumor Formation, Susceptibility to 29 MDM2

Anatomical Context for Accelerated Tumor Formation

Publications for Accelerated Tumor Formation

Articles related to Accelerated Tumor Formation:

# Title Authors Year
1
Accelerated tumor formation in a fatless mouse with type 2 diabetes and inflammation. ( 16707476 )
2006
2
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. ( 15550242 )
2004

Variations for Accelerated Tumor Formation

ClinVar genetic disease variations for Accelerated Tumor Formation:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 MDM2 NM_002392.5(MDM2): c.14+309T> G single nucleotide variant risk factor rs2279744 GRCh37 Chromosome 12, 69202580: 69202580
2 MDM2 NM_002392.5(MDM2): c.14+309T> G single nucleotide variant risk factor rs2279744 GRCh38 Chromosome 12, 68808800: 68808800
3 MDM2 NM_002392.5(MDM2): c.100-10C> A single nucleotide variant Benign rs56410897 GRCh37 Chromosome 12, 69207324: 69207324
4 MDM2 NM_002392.5(MDM2): c.100-10C> A single nucleotide variant Benign rs56410897 GRCh38 Chromosome 12, 68813544: 68813544
5 MDM2 NM_002392.5(MDM2): c.631A> C (p.Ile211Leu) single nucleotide variant Uncertain significance rs750452466 GRCh37 Chromosome 12, 69222658: 69222658
6 MDM2 NM_002392.5(MDM2): c.631A> C (p.Ile211Leu) single nucleotide variant Uncertain significance rs750452466 GRCh38 Chromosome 12, 68828878: 68828878
7 MDM2 NM_002392.5(MDM2): c.607C> T (p.Leu203=) single nucleotide variant Benign rs1795480 GRCh38 Chromosome 12, 68828854: 68828854
8 MDM2 NM_002392.5(MDM2): c.607C> T (p.Leu203=) single nucleotide variant Benign rs1795480 GRCh37 Chromosome 12, 69222634: 69222634
9 MDM2 NM_002392.5(MDM2): c.565C> T (p.Arg189Cys) single nucleotide variant Uncertain significance GRCh38 Chromosome 12, 68828812: 68828812
10 MDM2 NM_002392.5(MDM2): c.565C> T (p.Arg189Cys) single nucleotide variant Uncertain significance GRCh37 Chromosome 12, 69222592: 69222592

Expression for Accelerated Tumor Formation

Search GEO for disease gene expression data for Accelerated Tumor Formation.

Pathways for Accelerated Tumor Formation

GO Terms for Accelerated Tumor Formation

Sources for Accelerated Tumor Formation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....