MCID: ACC002
MIFTS: 20

Accommodative Spasm

Categories: Eye diseases

Aliases & Classifications for Accommodative Spasm

MalaCards integrated aliases for Accommodative Spasm:

Name: Accommodative Spasm 12 15
Spasm of Accommodation 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11637
ICD9CM 36 367.53
SNOMED-CT 69 30069002
ICD10 34 H52.53
UMLS 74 C0152196

Summaries for Accommodative Spasm

MalaCards based summary : Accommodative Spasm, also known as spasm of accommodation, is related to monocular esotropia and pathologic nystagmus. An important gene associated with Accommodative Spasm is GABRR3 (Gamma-Aminobutyric Acid Type A Receptor Rho3 Subunit (Gene/Pseudogene)). The drug Mydriatics has been mentioned in the context of this disorder. Affiliated tissues include eye and pineal.

Wikipedia : 77 A spasm of accommodation (also known as a ciliary spasm, an accommodation, or accommodative spasm) is a... more...

Related Diseases for Accommodative Spasm

Diseases related to Accommodative Spasm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 monocular esotropia 10.1
2 pathologic nystagmus 10.1
3 esotropia 10.1
4 photosensitive epilepsy 10.0
5 asthenopia 10.0
6 alternating exotropia 10.0
7 exotropia 10.0
8 myopia 10.0
9 epilepsy 10.0
10 pineal cyst 9.9

Graphical network of the top 20 diseases related to Accommodative Spasm:



Diseases related to Accommodative Spasm

Symptoms & Phenotypes for Accommodative Spasm

Drugs & Therapeutics for Accommodative Spasm

Drugs for Accommodative Spasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Mydriatics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Ultrasound Biomicroscopy Study Of Accommodative State In Smartphone Abusers Enrolling by invitation NCT03389009
2 Effect of VR and Accommdation Relax on Controlling Myopia in Children Not yet recruiting NCT03427697 Not Applicable

Search NIH Clinical Center for Accommodative Spasm

Genetic Tests for Accommodative Spasm

Anatomical Context for Accommodative Spasm

MalaCards organs/tissues related to Accommodative Spasm:

42
Eye, Pineal

Publications for Accommodative Spasm

Articles related to Accommodative Spasm:

(show all 34)
# Title Authors Year
1
A new treatment option for the resistant spasm of accommodation: clear lens extraction and multifocal intraocular lens implantation. ( 29376009 )
2018
2
Accommodative spasm might influence surgical planning and outcomes in acute acquired distance esotropia in myopia. ( 27515204 )
2016
3
Bimatoprost (0.03%)-induced accommodative spasm and pseudomyopia. ( 26598527 )
2015
4
The Role of Aberrometry in Accommodative Spasm After Myopic Photorefractive Keratectomy. ( 26653732 )
2015
5
Acute adult onset comitant esotropia associated with accommodative spasm. ( 24584303 )
2014
6
Functional spasm of accommodation: Changes on scheimpflug imaging. ( 25378883 )
2014
7
Accommodative spasm with bilateral vision loss due to untreated intermittent exotropia in an adult. ( 22864042 )
2012
8
Serial measurements of accommodation by open-field Hartmann-Shack wavefront aberrometer in eyes with accommodative spasm. ( 23008062 )
2012
9
Accommodative spasm in siblings: a unique finding. ( 20534925 )
2010
10
Accommodative spasm after laser-assisted in situ keratomileusis (LASIK). ( 17317414 )
2007
11
Accommodative spasm after laser-assisted in situ keratomileusis (LASIK). ( 16765703 )
2006
12
Spasm of accommodation in a patient with increased intracranial pressure and pineal cyst. ( 15785990 )
2005
13
Clear lens extraction for the treatment of persistent accommodative spasm after head trauma. ( 15617937 )
2004
14
Persistent accommodative spasm after severe head trauma. ( 12543762 )
2003
15
Wavefront analysis in eyes with accommodative spasm. ( 14644233 )
2003
16
Spasm of accommodation associated with closed head trauma. ( 11937900 )
2002
17
Nystagmus blockage syndrome associated with accommodative spasm. ( 11386654 )
2001
18
Acquired unilateral visual loss attributed to an accommodative spasm. ( 11503937 )
2001
19
Accommodative microfluctuation in asthenopia caused by accommodative spasm. ( 11764414 )
2001
20
Accommodative spasm. ( 3209787 )
1988
21
Accommodative spasm: a study of 17 cases. ( 3403901 )
1988
22
Persistent accommodative spasm nine years after head trauma. ( 2958503 )
1987
23
The polyphasic fogging method for revealing spasm of accommodation [proceedings]. ( 184651 )
1975
24
Another approach to the treatment of accommodative spasm. ( 4710222 )
1973
25
Spasm of accommodation. ( 4706101 )
1973
26
RECURRENT UNILATERAL ACCOMMODATIVE SPASM AND MIOSIS. ( 14332866 )
1965
27
Functional spasm of accommodation. ( 13618523 )
1959
28
Functional Spasm of Accommodation [Summary]. ( 19993965 )
1958
29
Spasm of accommodation. ( 18896811 )
1947
30
A case of accommodative spasm, following neglected convergence insufficiency with exophoria. ( 18899714 )
1947
31
Spasm of accommodation in myopia. ( 21027074 )
1946
32
FUNCTIONAL SPASM OF ACCOMMODATION. ( 18167715 )
1917
33
FUNCTIONAL SPASM OF ACCOMMODATION. ( 18167736 )
1917
34
Spasm of accommodation in glaucoma relieved by eserine. ( 25259327 )
1900

Variations for Accommodative Spasm

Expression for Accommodative Spasm

Search GEO for disease gene expression data for Accommodative Spasm.

Pathways for Accommodative Spasm

GO Terms for Accommodative Spasm

Cellular components related to Accommodative Spasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 8.62 GABRR3 KANTR

Sources for Accommodative Spasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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