Achenbach Syndrome disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Achenbach Syndrome

MalaCards integrated aliases for Achenbach Syndrome:

Name: Achenbach Syndrome ¹² ¹⁵ ¹⁷

Paroxysmal Hematoma of the Finger ¹²

Classifications:

MalaCards categories:
Anatomical: Skin diseases Blood diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:6687

NCIt ⁴⁹ C35467

SNOMED-CT ⁶⁷ 238824006

EFO ¹⁷ EFO_1000661

UMLS ⁷¹ C0473563

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Summaries for Achenbach Syndrome

MalaCards based summary : Achenbach Syndrome, also known as paroxysmal hematoma of the finger, is related to cyanosis, transient neonatal and critical illness polyneuropathy. An important gene associated with Achenbach Syndrome is F3 (Coagulation Factor III, Tissue Factor), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Complement and coagulation cascades. Affiliated tissues include skin.

Wikipedia : ⁷⁴ Paroxysmal hand hematoma is a skin condition characterized by spontaneous focal hemorrhage into the palm... more...

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Related Diseases for Achenbach Syndrome

Diseases related to Achenbach Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 208)

#	Related Disease	Score	Top Affiliating Genes
1	cyanosis, transient neonatal	10.1
2	critical illness polyneuropathy	10.0	F3 CRP
3	aspiration pneumonitis	10.0	F3 CRP
4	hantavirus hemorrhagic fever with renal syndrome	10.0	F3 CRP
5	multicentric castleman disease	10.0	F3 CRP
6	autoimmune disease of blood	10.0	F3 CRP
7	mycoplasma pneumoniae pneumonia	10.0	F3 CRP
8	angina pectoris	10.0	F3 CRP
9	scrub typhus	10.0	F3 CRP
10	intermediate coronary syndrome	10.0	F3 CRP
11	pyoderma	10.0	F3 CRP
12	carotid artery disease	9.9	F3 CRP
13	peripheral artery disease	9.9	F3 CRP
14	endocarditis	9.9	F2 CRP
15	orbital osteomyelitis	9.9	F2 CRP
16	small intestine diverticulitis	9.9	F2 CRP
17	hematocele of tunica vaginalis testis	9.9	F2 CRP
18	ascending cholangitis	9.9	F2 CRP
19	intracranial berry aneurysm	9.9	F3 CRP
20	splenic abscess	9.9	F2 CRP
21	acalculous cholecystitis	9.9	F2 CRP
22	cholesterol embolism	9.9	F2 CRP
23	abducens nerve disease	9.9	F2 CRP
24	branch retinal artery occlusion	9.9	F2 CRP
25	retinal artery occlusion	9.9	F2 CRP
26	acute cholangitis	9.9	F2 CRP
27	mastoiditis	9.9	F2 CRP
28	abdominal tuberculosis	9.9	F2 CRP
29	paralytic ileus	9.9	F2 CRP
30	ileus	9.9	F2 CRP
31	common bile duct disease	9.9	F2 CRP
32	bile duct disease	9.9	F2 CRP
33	pyuria	9.9	F2 CRP
34	toxic shock syndrome	9.9	F3 CRP
35	central retinal artery occlusion	9.9	F2 CRP
36	kwashiorkor	9.9	F2 CRP
37	pleural empyema	9.9	F2 CRP
38	hemorrhoid	9.9	F2 CRP
39	ischemic colitis	9.8	F2 CRP
40	retinal vascular occlusion	9.8	F2 CRP
41	choledocholithiasis	9.8	F2 CRP
42	plasma protein metabolism disease	9.8	F2 CRP
43	mitral valve insufficiency	9.8	F2 CRP
44	chronic venous insufficiency	9.8	F2 CRP
45	venous insufficiency	9.8	F2 CRP
46	portal vein thrombosis	9.8	F2 CRP
47	fournier gangrene	9.8	F3 F2
48	leptospirosis	9.8	F2 CRP
49	papillary adenofibroma	9.8	F3 F2
50	femoral neuropathy	9.8	F3 F2

Graphical network of the top 20 diseases related to Achenbach Syndrome:

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Symptoms & Phenotypes for Achenbach Syndrome

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Drugs & Therapeutics for Achenbach Syndrome

Search Clinical Trials , NIH Clinical Center for Achenbach Syndrome

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Genetic Tests for Achenbach Syndrome

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Anatomical Context for Achenbach Syndrome

MalaCards organs/tissues related to Achenbach Syndrome:

⁴⁰

Skin

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Publications for Achenbach Syndrome

Articles related to Achenbach Syndrome:

(show all 15)

#	Title	Authors	PMID	Year
1	Painful ecchymosis of the finger: a case of Achenbach syndrome. ⁶¹	Castillo SA...Werchniak AE	31353447	2020
2	Achenbach Syndrome: A Benign Painful Blue Finger with Tip Sparing. ⁶¹	Yie K	31915672	2019
3	[Spontaneous digital hematoma, Achenbach Sindrome.] ⁶¹	Picon Jaimes YA...Molina-Franky J	31833751	2019
4	Achenbach syndrome (paroxysmal finger hematoma). ⁶¹	Godoy A...Tabares AH	31159682	2019
5	Achenbach syndrome. ⁶¹	Notomi K...Harada T	31133606	2019
6	Analysis of 24 patients with Achenbach's syndrome. ⁶¹	Ada F...Kasimzade F	31183341	2019
7	Paroxysmal acral haematoma is a more appropriate name for Achenbach syndrome. ⁶¹	Pavlovic MD...Loubser MD	30430617	2019
8	Personal observations of Achenbach syndrome. ⁶¹	Cohen SN	29934997	2018
9	The Acutely Blue Finger: Cause for Concern? ⁶¹	Seifman MA...Johnstone BR	29734900	2018
10	[Paroxysmal finger haematoma (Achenbach syndrome)]. ⁶¹	Sigha B...Fardet L	26774542	2016
11	A case of spontaneous wrist haematoma in Achenbach syndrome. ⁶¹	Huikeshoven M...Engel AF	19675046	2009
12	[Raynaud phenomenon in dermatology. Part 1: Pathophysiology and diagnostic approach]. ⁶¹	Sunderkotter C...Riemekasten G	16902805	2006
13	[Recurrent painful cyanosis of fingers and palm. Recurrent paroxysmal finger hematoma (Achenbach syndrome)]. ⁶¹	Zimmerli L...Aschwanden M	12405037	2002
14	Achenbach syndrome. ⁶¹	Parslew R...Verbov JL	7888380	1995
15	[Paroxysmal finger hematoma (Achenbach syndrome)]. ⁶¹	Stieler W...Heinze-Werlitz C	2373612	1990

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Genes for Achenbach Syndrome

Genes related to Achenbach Syndrome (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	F3	Coagulation Factor III, Tissue Factor	Protein Coding	4.23	DISEASES inferred ¹⁵
2	F2	Coagulation Factor II, Thrombin	Protein Coding	4.1	DISEASES inferred ¹⁵
3	CRP	C-Reactive Protein	Protein Coding	3.44	DISEASES inferred ¹⁵

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Variations for Achenbach Syndrome

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Expression for Achenbach Syndrome

Search GEO for disease gene expression data for Achenbach Syndrome.

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Pathways for Achenbach Syndrome

Pathways related to Achenbach Syndrome according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Formation of Fibrin Clot (Clotting Cascade) ⁶⁵ Show member pathways Blood Clotting Cascade ¹ Blood Coagulation Signaling Pathways ⁶⁴ Common Pathway of Fibrin Clot Formation ⁶⁵ Extrinsic Pathway of Fibrin Clot Formation ⁶⁵ Extrinsic Prothrombin Activation Pathway ⁶³ Intrinsic Pathway of Fibrin Clot Formation ⁶⁵	11.16	F3 F2
2	Complement and coagulation cascades ³⁶ ¹	10.78	F3 F2

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GO Terms for Achenbach Syndrome

Biological processes related to Achenbach Syndrome according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	blood coagulation	GO:0007596	9.16	F3 F2
2	hemostasis	GO:0007599	8.96	F3 F2
3	acute-phase response	GO:0006953	8.62	F2 CRP

Molecular functions related to Achenbach Syndrome according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	serine-type endopeptidase activity	GO:0004252	8.62	F3 F2

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Sources for Achenbach Syndrome

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⁷⁴ Wikipedia