MCID: ACN001
MIFTS: 49

Acinar Cell Carcinoma

Categories: Cancer diseases, Rare diseases

Aliases & Classifications for Acinar Cell Carcinoma

MalaCards integrated aliases for Acinar Cell Carcinoma:

Name: Acinar Cell Carcinoma 12 15 17 74
Acinic Cell Carcinoma 12 54
Carcinoma, Acinar Cell 45
Carcinoma Acinar Cell 56
Acinic Cell Tumor 54
Acinar Cell Tumor 74

Classifications:



External Ids:

Disease Ontology 12 DOID:3025
MeSH 45 D018267
NCIt 51 C3768
SNOMED-CT 69 45410002

Summaries for Acinar Cell Carcinoma

Disease Ontology : 12 A carcinoma that has material basis in abnormally proliferating cells, derives from spindle cells and/or derives from giant cells.

MalaCards based summary : Acinar Cell Carcinoma, also known as acinic cell carcinoma, is related to pancreatic acinar cell adenocarcinoma and adenoma. An important gene associated with Acinar Cell Carcinoma is CHGA (Chromogranin A), and among its related pathways/superpathways are Endometrial cancer and Pathways in cancer. The drugs leucovorin and Levoleucovorin have been mentioned in the context of this disorder. Affiliated tissues include pancreas, salivary gland and breast, and related phenotypes are Decreased viability in esophageal squamous lineage and embryo

Related Diseases for Acinar Cell Carcinoma

Diseases related to Acinar Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 192)
# Related Disease Score Top Affiliating Genes
1 pancreatic acinar cell adenocarcinoma 33.0 AFP BCL10 CHGA
2 adenoma 30.4 CTNNB1 SMAD4 TP53
3 pancreatoblastoma 30.3 AFP CHGA SERPINA1
4 carcinosarcoma 29.9 CTNNB1 KRT7 TP53
5 pancreas adenocarcinoma 29.6 BRCA2 CTNNB1 SMAD4 TP53
6 adenoid cystic carcinoma 29.2 CTNNB1 KRT7 SERPINA3 TP53
7 hepatocellular carcinoma 28.6 AFP CTNNB1 KRT7 SERPINA1 SMAD4 TP53
8 acinar cell carcinoma of pancreas 12.7
9 panniculitis 10.5
10 adenocarcinoma 10.4
11 cellular ependymoma 10.4 CHGA TP53
12 synchronous bilateral breast carcinoma 10.4 BRCA2 TP53
13 fibroepithelial basal cell carcinoma 10.4 CHGA TP53
14 familial colorectal cancer type x 10.4 BRCA2 SMAD4
15 atypical follicular adenoma 10.4 CHGA TP53
16 olfactory groove meningioma 10.3 CHGA TP53
17 adult teratoma 10.3 AFP CHGA
18 sclerosing hepatic carcinoma 10.3 AFP CHGA
19 anterior cranial fossa meningioma 10.3 CHGA TP53
20 gastric lymphoma 10.3 BCL10 TP53
21 pulmonary blastoma 10.3 CHGA TP53
22 mutyh-associated polyposis 10.3 SMAD4 TP53
23 pleomorphic xanthoastrocytoma 10.3 CHGA TP53
24 urethral benign neoplasm 10.3 CHGA SMAD4
25 orofaciodigital syndrome viii 10.3 AFP BCL10
26 colloid carcinoma of the pancreas 10.3 BRCA2 SMAD4
27 liver sarcoma 10.3 AFP CHGA
28 small cell carcinoma of the bladder 10.3 CHGA KRT7
29 malignant teratoma 10.3 AFP TP53
30 gallbladder small cell carcinoma 10.3 CHGA KRT7
31 malignant spiradenoma 10.3 KRT7 TP53
32 spiradenoma 10.3 KRT7 TP53
33 esophagus adenocarcinoma 10.3 SMAD4 TP53
34 vulvar intraepithelial neoplasia 10.3 KRT7 TP53
35 mature teratoma 10.3 AFP TP53
36 pancreatic serous cystadenoma 10.3 CHGA KRT7
37 cervix small cell carcinoma 10.3 CHGA TP53
38 clear cell adenofibroma 10.3 BRCA2 KRT7
39 peritoneum cancer 10.3 BRCA2 KRT7
40 pancreatitis 10.3
41 bladder carcinoma in situ 10.3 KRT7 TP53
42 ampulla of vater adenocarcinoma 10.3 BRCA2 KRT7
43 vulvar disease 10.3 KRT7 TP53
44 papillary serous adenocarcinoma 10.3 KRT7 TP53
45 gastric cardia carcinoma 10.3 CHGA SMAD4
46 nasal cavity adenocarcinoma 10.3 KRT7 TP53
47 intrahepatic bile duct adenoma 10.3 AFP KRT7
48 prostate squamous cell carcinoma 10.3 KRT7 TP53
49 cerebellar liponeurocytoma 10.2 CHGA TP53
50 pleomorphic carcinoma 10.2 KRT7 TP53

Graphical network of the top 20 diseases related to Acinar Cell Carcinoma:



Diseases related to Acinar Cell Carcinoma

Symptoms & Phenotypes for Acinar Cell Carcinoma

GenomeRNAi Phenotypes related to Acinar Cell Carcinoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.23 AFP BCL10 BRCA2 CHGA CTNNB1 KRT7

MGI Mouse Phenotypes related to Acinar Cell Carcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 9.63 BCL10 BRCA2 CTNNB1 ETV6 SMAD4 TP53
2 endocrine/exocrine gland MP:0005379 9.56 AFP BCL10 BRCA2 CHGA CTNNB1 ETV6
3 neoplasm MP:0002006 9.1 AFP BRCA2 CTNNB1 ETV6 SMAD4 TP53

Drugs & Therapeutics for Acinar Cell Carcinoma

Drugs for Acinar Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 119)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
leucovorin Approved Phase 3,Phase 2,Phase 1,Early Phase 1 58-05-9 143 6006
2
Levoleucovorin Approved, Investigational Phase 3,Phase 2,Phase 1 68538-85-2
3
Pancrelipase Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 53608-75-6
4
Fluorouracil Approved Phase 3,Phase 2,Phase 1,Early Phase 1 51-21-8 3385
5
Gemcitabine Approved Phase 3,Phase 2,Phase 1,Early Phase 1 95058-81-4 60750
6
Histamine Approved, Investigational Phase 3 51-45-6 774
7
Doxepin Approved, Investigational Phase 3 1668-19-5 667468 667477
8
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
9
Promethazine Approved, Investigational Phase 3 60-87-7 4927
10
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
11
Capecitabine Approved, Investigational Phase 3,Phase 2,Early Phase 1 154361-50-9 60953
12
Calcium Approved, Nutraceutical Phase 3,Phase 2,Phase 1 7440-70-2 271
13
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
14 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
15 Hormones Phase 3,Phase 2,Phase 1
16 Trace Elements Phase 3,Phase 2,Phase 1
17 Antiviral Agents Phase 3,Phase 2,Phase 1,Early Phase 1
18 Immunosuppressive Agents Phase 3,Phase 2,Phase 1,Early Phase 1
19 Antidotes Phase 3,Phase 2,Phase 1
20 Vitamin B9 Phase 3,Phase 2,Phase 1
21 pancreatin Phase 3,Phase 2,Phase 1,Not Applicable
22 Anti-Infective Agents Phase 3,Phase 2,Phase 1,Early Phase 1
23 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1,Early Phase 1
24 Nutrients Phase 3,Phase 2,Phase 1
25 Protective Agents Phase 3,Phase 2,Phase 1
26 Vitamin B Complex Phase 3,Phase 2,Phase 1
27 Folate Phase 3,Phase 2,Phase 1
28 Vitamins Phase 3,Phase 2,Phase 1
29 Immunologic Factors Phase 3,Phase 2,Phase 1,Early Phase 1
30 Antimetabolites Phase 3,Phase 2,Phase 1,Early Phase 1
31 Calcium, Dietary Phase 3,Phase 2,Phase 1
32 Micronutrients Phase 3,Phase 2,Phase 1
33 Histamine Antagonists Phase 3
34 Psychotropic Drugs Phase 3
35 Neurotransmitter Agents Phase 3
36 Central Nervous System Depressants Phase 3
37 Antidepressive Agents, Tricyclic Phase 3
38 Antidepressive Agents Phase 3
39
Histamine Phosphate Phase 3 51-74-1 65513
40 Hypnotics and Sedatives Phase 3
41 Narcotics Phase 3
42 Adjuvants, Anesthesia Phase 3
43 Analgesics Phase 3
44 Anesthetics, Intravenous Phase 3
45 Liver Extracts Phase 3,Phase 1,Early Phase 1
46 Anesthetics, General Phase 3
47 Anesthetics Phase 3
48 Analgesics, Opioid Phase 3
49 Peripheral Nervous System Agents Phase 3
50 Cola Phase 3,Early Phase 1

Interventional clinical trials:

(show all 47)
# Name Status NCT ID Phase Drugs
1 Two Chemotherapy Regimens Compared With Observation in Treating Patients With Completely Resected Pancreatic Cancer Completed NCT00058201 Phase 3 fluorouracil;gemcitabine hydrochloride;leucovorin calcium
2 Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy Completed NCT01156142 Phase 3 doxepin hydrochloride
3 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
4 Acelarin First Line Randomised Pancreatic Study Recruiting NCT03610100 Phase 2, Phase 3 Acelarin;Gemcitabine
5 Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery Active, not recruiting NCT01013649 Phase 3 Capecitabine;Chemotherapy;Erlotinib Hydrochloride;Fluorouracil;Gemcitabine Hydrochloride
6 Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy Completed NCT01658943 Phase 2 Akt Inhibitor MK2206;Fluorouracil;Oxaliplatin;Selumetinib
7 Carboplatin and Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Metastatic Pancreatic Cancer Completed NCT01280058 Phase 2 Carboplatin;Paclitaxel
8 Bortezomib and Carboplatin in Treating Patients With Metastatic Pancreatic Cancer Completed NCT00416793 Phase 2 bortezomib;carboplatin
9 Gemcitabine in Treating Patients With Advanced Salivary Gland Cancer That Cannot Be Removed During Surgery Completed NCT00003744 Phase 2 gemcitabine
10 Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer Completed NCT01666730 Phase 2 metformin hydrochloride;oxaliplatin;leucovorin calcium;fluorouracil
11 Sunitinib in Treating Patients With Metastatic Pancreatic Cancer That Progressed After First-Line Therapy With Gemcitabine Completed NCT00397787 Phase 2 sunitinib malate
12 Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas Completed NCT00085371 Phase 2 triapine
13 Paclitaxel and Bryostatin 1 in Treating Patients With Advanced Pancreatic Cancer Completed NCT00031694 Phase 2 paclitaxel;bryostatin 1
14 Dasatinib and Gemcitabine Hydrochloride or Gemcitabine Hydrochloride Alone in Treating Patients With Pancreatic Cancer Previously Treated With Surgery Completed NCT01234935 Phase 2 dasatinib;gemcitabine hydrochloride
15 Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary Gland Cancers Completed NCT00095563 Phase 2 lapatinib ditosylate
16 Trastuzumab in Treating Patients With Advanced Salivary Gland Cancer Completed NCT00004163 Phase 2 Trastuzumab
17 Cisplatin or Carboplatin Combined With Gemcitabine in Treating Patients With Locally Advanced, Recurrent, or Metastatic Malignant Salivary Gland Tumor Completed NCT00079079 Phase 2 carboplatin;cisplatin;gemcitabine hydrochloride
18 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
19 Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer Recruiting NCT02047474 Phase 2 oxaliplatin;leucovorin calcium;irinotecan hydrochloride;fluorouracil
20 Selinexor, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Metastatic Pancreatic Cancer Active, not recruiting NCT02178436 Phase 1, Phase 2 gemcitabine hydrochloride;paclitaxel albumin-stabilized nanoparticle formulation;selinexor
21 Mitomycin C and Ifosfamide in Treating Patients With Metastatic Pancreatic Cancer Terminated NCT00967291 Phase 2 ifosfamide;mitomycin C
22 Trastuzumab in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer Terminated NCT00126607 Phase 2
23 Title XELOX FOR SALIVARY GLAND CANCERS Terminated NCT00101075 Phase 2 Capecitabine;Oxaliplatin
24 Ultrasound-Guided Photodynamic Therapy With Photofrin & Gemcitabine for Patients With Locally Advanced Pancreatic Cancer Completed NCT01770132 Phase 1 porfimer sodium;gemcitabine hydrochloride
25 CPI-613 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer Completed NCT01839981 Phase 1 6,8-bis(benzylthio)octanoic acid
26 Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgery Completed NCT01537107 Phase 1 vismodegib;sirolimus
27 Sorafenib Tosylate and Everolimus in Treating Patients With Advanced Solid Tumors and Metastatic Pancreatic Cancer That Does Not Respond to Gemcitabine Hydrochloride Completed NCT00981162 Phase 1 sorafenib tosylate;everolimus
28 Vaccine Therapy and Sargramostim in Treating Patients With Pancreas Cancer That Cannot Be Removed By Surgery Active, not recruiting NCT00669734 Phase 1
29 CPI-613 and Combination Chemotherapy in Treating Patients With Metastatic Pancreatic Cancer Active, not recruiting NCT01835041 Phase 1 6,8-bis(benzylthio)octanoic acid;oxaliplatin;leucovorin calcium;irinotecan hydrochloride;fluorouracil
30 GDC-0449 and Erlotinib Hydrochloride With or Without Gemcitabine Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer or Solid Tumors That Cannot Be Removed by Surgery Active, not recruiting NCT00878163 Phase 1 Erlotinib Hydrochloride;Gemcitabine Hydrochloride;Vismodegib
31 Alisertib and Gemcitabine Hydrochloride in Treating Patients With Solid Tumors or Pancreatic Cancer Active, not recruiting NCT01924260 Phase 1 alisertib;gemcitabine
32 Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies Active, not recruiting NCT01643499 Phase 1 oxaliplatin;irinotecan hydrochloride;leucovorin calcium;fluorouracil
33 Chemoradiation and Radiosurgery Boost in Treating Patients With Locally Advance Pancreatic Cancer That May or May Not be Removed by Surgery Terminated NCT01739439 Phase 1 gemcitabine hydrochloride
34 Dynamic Contrast Enhanced MRI in Patients With Advanced Breast or Pancreatic Cancer With Metastases to the Liver or Lung Withdrawn NCT01741597 Phase 1
35 Chemotherapy and Radiation Therapy Before Surgery Followed by Gemcitabine in Treating Patients With Pancreatic Cancer Completed NCT01821612 Early Phase 1 oxaliplatin;irinotecan;leucovorin;5-fluorouracil;capecitabine;gemcitabine
36 MRI Mapping in Planning Radiation Therapy to the Base of Skull and Brain in Patients With Nonmetastatic Head and Neck Cancer Completed NCT00984074
37 Growth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial Cancer Completed NCT00897793
38 Stereotactic Radiosurgery in Treating Patients With Locally Advanced or Recurrent Head and Neck Cancer Completed NCT00851253 Not Applicable
39 Using Traditional Acupuncture in the Management of Cancer Treatment Related Lymphoedema Completed NCT00828516 Not Applicable
40 PET Scans in Patients With Head And Neck Cancer Who Are Undergoing 3-Dimensional Conformal Radiation Therapy And Intensity-Modulated Radiation Therapy Completed NCT00809016 Not Applicable
41 Head & Neck Cancer Survivorship: Physical and Functional Status Completed NCT00751816 systemic chemotherapy
42 Family Quality of Life Among Families With a Member Who is a Cancer Patient Completed NCT00544336
43 High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery Recruiting NCT02757859 Not Applicable
44 Incidence of POPF in the Resection of the Left Pancreas With RFAT Recruiting NCT03570502
45 Stereotactic Radiosurgery and Metformin in Patients With Borderline-Resectable or Locally-Advanced Pancreatic Cancer Active, not recruiting NCT02153450 Early Phase 1 metformin hydrochloride
46 Surgery for Pancreatic Tumors and Collection of Tumor Tissue for Study Terminated NCT00100321
47 Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer Terminated NCT00499733 Early Phase 1 cyclophosphamide

Search NIH Clinical Center for Acinar Cell Carcinoma

Cochrane evidence based reviews: carcinoma, acinar cell

Genetic Tests for Acinar Cell Carcinoma

Anatomical Context for Acinar Cell Carcinoma

MalaCards organs/tissues related to Acinar Cell Carcinoma:

42
Pancreas, Salivary Gland, Breast, Lung, Liver, Brain, Ovary

Publications for Acinar Cell Carcinoma

Articles related to Acinar Cell Carcinoma:

(show top 50) (show all 557)
# Title Authors Year
1
Nuclear NR4A3 Immunostaining is a Specific and Sensitive Novel Marker for Acinic Cell Carcinoma of the Salivary Glands. ( 31094928 )
2019
2
Metastatic acinic cell carcinoma of the parotid gland to the abdominal wall. ( 30967939 )
2019
3
Primary Pulmonary Acinic Cell Carcinoma: A Clinicopathological Study of 6 Cases and Literature Review. ( 30898020 )
2019
4
Surgery Alone Is Effective in the Management of Pediatric Salivary Gland Acinic Cell Carcinoma. ( 30825434 )
2019
5
Immunohistochemistry Using a Pan-TRK Antibody Distinguishes Secretory Carcinoma of Salivary Gland from Acinic Cell Carcinoma. ( 30801752 )
2019
6
The HTN3-MSANTD3 Fusion Gene Defines a Subset of Acinic Cell Carcinoma of the Salivary Gland. ( 30520817 )
2019
7
Mucoepidermoid carcinoma, acinic cell carcinoma, and adenoid cystic carcinoma on fine-needle aspiration biopsy and The Milan System: an international multi-institutional study. ( 31104944 )
2019
8
Acinar Cell Carcinoma of Pancreas: a Case Report and Review of Literature. ( 28660524 )
2019
9
MR imaging features of pancreatic acinar cell carcinoma. ( 30846400 )
2019
10
Mixed ductal-acinar cell carcinoma of the pancreas: A case report. ( 30967946 )
2019
11
Pancreatic acinar cell carcinoma is associated with BRCA2 germline mutations: a case report and literature review. ( 31002019 )
2019
12
Pancreatic Ductal Adenocarcinoma Development in the Remnant Pancreas after Pancreaticoduodenectomy for Acinar Cell Carcinoma: A Case Report. ( 31061255 )
2019
13
Acinic Cell Carcinoma of the Parotid Gland in Children and Adolescents. ( 29240035 )
2018
14
Papillary Pattern in Acinic Cell Carcinoma of Parotid Gland: A Potential Diagnostic Pitfall on FNAC. ( 29403174 )
2018
15
Synchronous Parotid (Mammary Analog) Secretory Carcinoma and Acinic Cell Carcinoma: Report of a Case. ( 29876739 )
2018
16
Primary acinic cell carcinoma of the esophagus. ( 30552027 )
2018
17
Acinic cell carcinoma of parotid gland with cavernous sinus metastasis: A case report. ( 30488869 )
2018
18
Primary acinic cell carcinoma of the breast: A case report with a clinicopathological and immunohistochemical study of a rare breast cancer subtype. ( 30305896 )
2018
19
Hemorrhage of MRI and Immunohistochemical Panels Distinguish Secretory Carcinoma From Acinic Cell Carcinoma. ( 30186957 )
2018
20
Acinic cell carcinoma of the parotid gland in pregnancy: an approach to cancer in pregnancy. ( 30042101 )
2018
21
Close Margins and Adjuvant Radiotherapy in Acinic Cell Carcinoma of the Parotid Gland. ( 29978180 )
2018
22
Four-Year Survival of a Patient With Spinal Metastatic Acinic Cell Carcinoma After a Total En Bloc Spondylectomy and Reconstruction With a Frozen Tumor-Bearing Bone Graft. ( 29913031 )
2018
23
Outcomes and prognostic factors for parotid acinic cell Carcinoma: A National Cancer Database study of 2362 cases. ( 29909902 )
2018
24
Central Acinic Cell Carcinoma of the Mandible Simulating as Benign Odontogenic Lesion: A Case Report. ( 29749993 )
2018
25
MR imaging features of mammary analogue secretory carcinoma and acinic cell carcinoma of the salivary gland: a preliminary report. ( 29493279 )
2018
26
Curative distal pancreatectomy in patients with acinar cell carcinoma of pancreas diagnosed by endoscopic aspiration via esophago-jejunostomy: A successful case report. ( 29331883 )
2018
27
BRAF gene rearrangements can be identified by FISH studies in pancreatic acinar cell carcinoma. ( 29506751 )
2018
28
Pancreatic panniculitis as a presentation symptom of acinar cell carcinoma. ( 29527901 )
2018
29
Hepatobiliary and Pancreatic: Primary acinar cell carcinoma of the liver showing good response to chemotherapy. ( 29659083 )
2018
30
EGFR amplification induces sensitivity to antiEGFR therapy in pancreatic acinar cell carcinoma. ( 29666669 )
2018
31
Surgical resection of hepatic and rectal metastases of pancreatic acinar cell carcinoma (PACC): a case report. ( 30075727 )
2018
32
Pancreatic Acinar Cell Carcinoma with Multiple Liver Metastases Effectively Treated by S-1 Chemotherapy. ( 30101903 )
2018
33
Pancreatic acinar cell carcinoma-induced panniculitis. ( 30128347 )
2018
34
Prevention of pancreatic acinar cell carcinoma by Roux-en-Y Gastric Bypass Surgery. ( 30305629 )
2018
35
Response of germline BRCA2-mutated advanced pancreatic acinar cell carcinoma to olaparib: A case report. ( 30407325 )
2018
36
Pancreatic acinar cell carcinoma-case report and literature review. ( 30409114 )
2018
37
Underutilization of surgical resection in patients with pancreatic acinar cell carcinoma. ( 30514625 )
2018
38
Nomogram to Predict Cancer-Specific Survival in Patients with Pancreatic Acinar Cell Carcinoma: A Competing Risk Analysis. ( 30519311 )
2018
39
Indolent T-lymphoblastic proliferation concomitant with acinic cell carcinoma mimicking T-lymphoblastic lymphoma: case report and literature review. ( 29143359 )
2018
40
Combined DOG1 and Mammaglobin Immunohistochemistry Is Comparable to ETV6-breakapart Analysis for Differentiating Between Papillary Cystic Variants of Acinic Cell Carcinoma and Mammary Analogue Secretory Carcinoma. ( 27670353 )
2017
41
Utility of Immunohistochemistry and ETV6 (12p13) Gene Rearrangement in Identifying Secretory Carcinoma of Salivary Gland among Previously Diagnosed Cases of Acinic Cell Carcinoma. ( 28484662 )
2017
42
High-Grade Transformation (Dedifferentiation) of Acinic Cell Carcinoma of the Parotid Gland: Report of an Unusual Variant. ( 28589053 )
2017
43
Two Cases of Acinic Cell Carcinoma of Parotid Gland - Rare Papillary Cystic Variant: One Unusual Presentation in Older Male Patient. ( 28900343 )
2017
44
So-called acinic cell carcinoma of the breast arises from microgladular adenosis and is not a distinct entity. ( 28972583 )
2017
45
Pure acinic cell carcinoma of the breast: A case report and literature review. ( 29382006 )
2017
46
Acinic cell carcinoma of minor salivary glands - case report. ( 29250681 )
2017
47
Metastatic Acinic Cell Carcinoma to the Vagina: A First Reported Case. ( 28800013 )
2017
48
Acinic Cell Carcinoma Papillary-Cystic Variant: Diagnostic Pitfalls in Fine Needle Aspiration Cytology. ( 28658776 )
2017
49
Ultrasound features of acinic cell carcinoma of the tongue: a rare case report. ( 28396757 )
2017
50
Primary acinic cell carcinoma of the lung with psammoma bodies: A case report and review of literature. ( 28214199 )
2017

Variations for Acinar Cell Carcinoma

Copy number variations for Acinar Cell Carcinoma from CNVD:

7
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 118120 17 7571720 7590868 Mutation TP53 Acinar cell carcinoma
2 107120 19 1205798 1228434 Amplification LKB1 Acinar cell carcinoma

Expression for Acinar Cell Carcinoma

Search GEO for disease gene expression data for Acinar Cell Carcinoma.

Pathways for Acinar Cell Carcinoma

GO Terms for Acinar Cell Carcinoma

Biological processes related to Acinar Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to gamma radiation GO:0010332 9.46 BRCA2 TP53
2 cell proliferation GO:0008283 9.46 BRCA2 CTNNB1 SMAD4 TP53
3 cell aging GO:0007569 9.43 BRCA2 TP53
4 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 9.4 BRCA2 TP53
5 female gonad development GO:0008585 9.37 BRCA2 SMAD4
6 gastrulation with mouth forming second GO:0001702 9.32 CTNNB1 SMAD4
7 positive regulation of histone H3-K4 methylation GO:0051571 9.26 CTNNB1 SMAD4
8 positive regulation of transcription, DNA-templated GO:0045893 9.02 BCL10 CTNNB1 BRCA2 SMAD4 TP53
9 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.96 BRCA2 TP53

Molecular functions related to Acinar Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.65 BCL10 BRCA2 SERPINA1 SMAD4 TP53
2 protein C-terminus binding GO:0008022 9.5 BCL10 BRCA2 CTNNB1
3 I-SMAD binding GO:0070411 9.16 CTNNB1 SMAD4
4 RNA polymerase II transcription factor binding GO:0001085 9.13 CTNNB1 SMAD4 TP53
5 protease binding GO:0002020 8.92 BCL10 BRCA2 SERPINA1 TP53

Sources for Acinar Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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