MCID: ACN007
MIFTS: 23

Acinar Cell Cystadenocarcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Acinar Cell Cystadenocarcinoma

MalaCards integrated aliases for Acinar Cell Cystadenocarcinoma:

Name: Acinar Cell Cystadenocarcinoma 12 15 72
Pancreatic Acinar Cell Cystadenocarcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7729
NCIt 50 C3874 C5727
UMLS 72 C1266087

Summaries for Acinar Cell Cystadenocarcinoma

MalaCards based summary : Acinar Cell Cystadenocarcinoma, also known as pancreatic acinar cell cystadenocarcinoma, is related to cystadenocarcinoma and hypereosinophilic syndrome, and has symptoms including abdominal pain, pruritus and icterus. An important gene associated with Acinar Cell Cystadenocarcinoma is SERPINA3 (Serpin Family A Member 3). Affiliated tissues include pancreas.

Related Diseases for Acinar Cell Cystadenocarcinoma

Diseases related to Acinar Cell Cystadenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 94)
# Related Disease Score Top Affiliating Genes
1 cystadenocarcinoma 10.5
2 hypereosinophilic syndrome 10.2
3 tubular adenocarcinoma 10.1 SYP CHGA
4 ureter small cell carcinoma 10.1 SYP CHGA
5 small cell carcinoma 10.1 SYP CHGA
6 gastric cardia carcinoma 10.1 MUC5AC CHGA
7 esophageal neuroendocrine tumor 10.1 SYP CHGA
8 neuroendocrine tumor 10.1 SYP CHGA
9 urinary bladder small cell neuroendocrine carcinoma 10.1 SYP CHGA
10 ovarian large-cell neuroendocrine carcinoma 10.1 SYP CHGA
11 auditory system cancer 10.1 SYP CHGA
12 primary hepatic neuroendocrine carcinoma 10.1 SYP CHGA
13 cellular ependymoma 10.1 SYP CHGA
14 peritoneal serous adenocarcinoma 10.1 SYP CHGA
15 small cell carcinoma of the bladder 10.1 SYP CHGA
16 gastrointestinal neuroendocrine tumor 10.1 SYP CHGA
17 chordoid meningioma 10.1 SYP CHGA
18 atypical follicular adenoma 10.1 SYP CHGA
19 gallbladder small cell carcinoma 10.1 SYP CHGA
20 pulmonary large cell neuroendocrine carcinoma 10.1 SYP CHGA
21 large cell neuroendocrine carcinoma 10.1 SYP CHGA
22 olfactory groove meningioma 10.1 SYP CHGA
23 cauda equina neoplasm 10.1 SYP CHGA
24 panophthalmitis 10.1 SYP MUC5AC
25 conventional angiosarcoma 10.1 SYP CHGA
26 pancreatic serous cystadenoma 10.1 SYP CHGA
27 cystadenoma 10.1 SYP CHGA
28 olfactory nerve neoplasm 10.1 SYP CHGA
29 nodular ganglioneuroblastoma 10.1 SYP CHGA
30 autonomic nervous system benign neoplasm 10.1 SYP CHGA
31 pineocytoma 10.1 SYP CHGA
32 panniculitis 10.1
33 adenocarcinoma 10.1
34 pulmonary sclerosing hemangioma 10.1 SYP CHGA
35 sclerosing hemangioma 10.1 SYP CHGA
36 hemangioma 10.1 SYP CHGA
37 subependymoma 10.1 SYP CHGA
38 gastric small cell carcinoma 10.1 SYP CHGA
39 anterior cranial fossa meningioma 10.1 SYP CHGA
40 mucinous ovarian cystadenoma 10.1 SYP MUC5AC
41 respiratory system benign neoplasm 10.1 SYP CHGA
42 carcinoid tumors, intestinal 10.1 SYP CHGA
43 non-functioning pancreatic endocrine tumor 10.1 SYP CHGA
44 papillary ependymoma 10.1 SYP CHGA
45 tanycytic ependymoma 10.1 SYP CHGA
46 pleomorphic xanthoastrocytoma 10.1 SYP CHGA
47 pulmonary blastoma 10.1 SYP CHGA
48 ovarian mucinous neoplasm 10.1 SYP MUC5AC
49 carcinoid syndrome 10.1 SYP CHGA
50 binswanger's disease 10.0 SYP CHGA

Graphical network of the top 20 diseases related to Acinar Cell Cystadenocarcinoma:



Diseases related to Acinar Cell Cystadenocarcinoma

Symptoms & Phenotypes for Acinar Cell Cystadenocarcinoma

UMLS symptoms related to Acinar Cell Cystadenocarcinoma:


abdominal pain, pruritus, icterus

Drugs & Therapeutics for Acinar Cell Cystadenocarcinoma

Search Clinical Trials , NIH Clinical Center for Acinar Cell Cystadenocarcinoma

Genetic Tests for Acinar Cell Cystadenocarcinoma

Anatomical Context for Acinar Cell Cystadenocarcinoma

MalaCards organs/tissues related to Acinar Cell Cystadenocarcinoma:

41
Pancreas

Publications for Acinar Cell Cystadenocarcinoma

Articles related to Acinar Cell Cystadenocarcinoma:

# Title Authors PMID Year
1
Acinar Cell Cystadenocarcinoma of the Pancreas. 38
29033770 2017
2
Diagnostic challenge: intraductal neoplasms of the pancreatobiliary system. 38
23057996 2012
3
Acinar cell cystadenocarcinoma of the pancreas in a 4-year-old child. 38
17003655 2006
4
Acinar cell cystadenocarcinoma of the pancreas: report of rare case and review of the literature. 38
15619219 2004
5
Pancreatic panniculitis in a patient with an acinar cell cystadenocarcinoma of the pancreas. 38
15118385 2004
6
[Serous microcystic adenoma of the pancreas: cytologic and histologic features]. 38
14663926 2003
7
Cystic forms of typically solid pancreatic tumors. 38
10721809 2000
8
Acinar cell cystadenocarcinoma of the pancreas. 38
2444326 1987
9
Acinar cell cystadenocarcinoma of human pancreas. 38
7459828 1981

Variations for Acinar Cell Cystadenocarcinoma

Expression for Acinar Cell Cystadenocarcinoma

Search GEO for disease gene expression data for Acinar Cell Cystadenocarcinoma.

Pathways for Acinar Cell Cystadenocarcinoma

GO Terms for Acinar Cell Cystadenocarcinoma

Cellular components related to Acinar Cell Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.46 SERPINA3 SERPINA1 MUC5AC CHGA
2 extracellular space GO:0005615 9.26 SERPINA3 SERPINA1 MUC5AC CHGA
3 platelet alpha granule lumen GO:0031093 8.62 SERPINA3 SERPINA1

Biological processes related to Acinar Cell Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of endopeptidase activity GO:0010951 9.26 SERPINA3 SERPINA1
2 platelet degranulation GO:0002576 9.16 SERPINA3 SERPINA1
3 negative regulation of peptidase activity GO:0010466 8.96 SERPINA3 SERPINA1
4 acute-phase response GO:0006953 8.62 SERPINA3 SERPINA1

Molecular functions related to Acinar Cell Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase inhibitor activity GO:0030414 8.96 SERPINA3 SERPINA1
2 serine-type endopeptidase inhibitor activity GO:0004867 8.62 SERPINA3 SERPINA1

Sources for Acinar Cell Cystadenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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